[ { "url": "https://psychonautwiki.org/wiki/1,4-Butanediol", "name": "1,4-Butanediol", "aliases": [ "1,4-B", "BD", "BDO", "Butylene Glycol", "One Comma Four", "One Four Bee", "or One Four B-D-O" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 0.5 mL" }, { "name": "Light", "value": "0.5 - 1 mL" }, { "name": "Common", "value": "1 - 2.5 mL" }, { "name": "Strong", "value": "2.5 - 4 mL" }, { "name": "Heavy", "value": "4 mL +", "note": "Warning: Doses above 4 mL can induce heavy sleep and doses above 6 mL can lead to poisoning" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "20 minutes - 60 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1.5 - 2 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Diol", "Alkanediol" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within several weeks of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately physically and psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/1B-LSD", "name": "1B-LSD", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 \u00b5g" }, { "name": "Light", "value": "25 - 75 \u00b5g" }, { "name": "Common", "value": "75 - 150 \u00b5g" }, { "name": "Strong", "value": "150 - 300 \u00b5g" }, { "name": "Heavy", "value": "300 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "45 - 120 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "3 - 5 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "extremely low toxicity relative to dose" ], "addictionPotential": "non-addictive with a low abuse potential", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/1P-ETH-LAD", "name": "1P-ETH-LAD", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 \u00b5g" }, { "name": "Light", "value": "30 - 60 \u00b5g" }, { "name": "Common", "value": "60 - 100 \u00b5g" }, { "name": "Strong", "value": "100 - 200 \u00b5g" }, { "name": "Heavy", "value": "200 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "6 - 12 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/1P-LSD", "name": "1P-LSD", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 \u00b5g" }, { "name": "Light", "value": "25 - 75 \u00b5g" }, { "name": "Common", "value": "75 - 150 \u00b5g" }, { "name": "Strong", "value": "150 - 300 \u00b5g" }, { "name": "Heavy", "value": "300 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "45 - 120 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "3 - 5 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "extremely low toxicity relative to dose" ], "addictionPotential": "non-addictive with a low abuse potential", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2-Aminoindane", "name": "2-Aminoindane", "aliases": [ "2-AI" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Aminoindane" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/2-FA", "name": "2-FA", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "15 - 30 mg" }, { "name": "Common", "value": "30 - 50 mg" }, { "name": "Strong", "value": "50 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 10 days" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/2-FEA", "name": "2-FEA", "aliases": [], "roas": [ { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "20 - 30 mg" }, { "name": "Common", "value": "30 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2.5 hours" }, { "name": "Onset", "value": "5 - 15 minutes" }, { "name": "Come up", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "30 - 60 minutes" }, { "name": "Offset", "value": "30 - 60 minutes" }, { "name": "After effects", "value": "1 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/2-FMA", "name": "2-FMA", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "7 - 9 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Come up", "value": "15 - 40 minutes" }, { "name": "Peak", "value": "2.5 - 4 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "4 - 12 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "10 - 20 minutes" }, { "name": "Peak", "value": "1 - 3 hours" }, { "name": "Offset", "value": "1.5 - 3 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/2-Fluorodeschloroketamine", "name": "2-Fluorodeschloroketamine", "aliases": [ "2-FDCK", "2-FK", "2-Fluoroketamine", "Fluoroketamine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 70 mg" }, { "name": "Strong", "value": "70 - 140 mg" }, { "name": "Heavy", "value": "140 mg+" } ], "duration": [ { "name": "Total", "value": "2.5 - 5.0 hours" }, { "name": "Onset", "value": "15 - 50 minutes" }, { "name": "Peak", "value": "50 - 100 minutes" }, { "name": "After effects", "value": "3 - 8 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 45 mg" }, { "name": "Common", "value": "45 - 100 mg" }, { "name": "Strong", "value": "100 - 175 mg" }, { "name": "Heavy", "value": "175 mg +" } ], "duration": [ { "name": "Total", "value": "1.5 - 3 hours" }, { "name": "Onset", "value": "1 - 3 minutes" }, { "name": "Come up", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "1 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/25B-NBOH", "name": "25B-NBOH", "aliases": [], "roas": [], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "1 week", "zero": "2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/25B-NBOMe", "name": "25B-NBOMe", "aliases": [], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "100 - 300 \u00b5g" }, { "name": "Common", "value": "300 - 500 \u00b5g" }, { "name": "Strong", "value": "500 - 700 \u00b5g" }, { "name": "Heavy", "value": null, "note": "25B-NBOMe can be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "25 \u00b5g" }, { "name": "Light", "value": "50 - 200 \u00b5g" }, { "name": "Common", "value": "200 - 350 \u00b5g" }, { "name": "Strong", "value": "350 - 500 \u00b5g" }, { "name": "Heavy", "value": null, "note": "25B-NBOMe can be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "2 - 5 minutes" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "1 week", "zero": "2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/25C-NBOH", "name": "25C-NBOH", "aliases": [], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "100 \u00b5g" }, { "name": "Light", "value": "250 - 500 \u00b5g" }, { "name": "Common", "value": "500 - 750 \u00b5g" }, { "name": "Strong", "value": "750 - 1000 \u00b5g" }, { "name": "Heavy", "value": null, "note": "25C-NBOH may be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "5 - 7 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "After effects", "value": "3 - 6 days" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "1 week", "zero": "2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/25C-NBOMe", "name": "25C-NBOMe", "aliases": [ "2C-C-NBOMe", "Cimbi-82", "NBOMe-2C-C" ], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "100 - 300 \u00b5g" }, { "name": "Common", "value": "300 - 700 \u00b5g" }, { "name": "Strong", "value": "700 - 1000 \u00b5g" }, { "name": "Heavy", "value": null, "note": "25C-NBOMe can be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "8 - 10 hours" }, { "name": "Onset", "value": "0 - 15 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "Offset", "value": "1 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "7 days", "zero": "14 days" }, "toxicity": [ "fatal at heavy dosages" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/25D-NBOMe", "name": "25D-NBOMe", "aliases": [], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "300 \u00b5g" }, { "name": "Light", "value": "300 - 800 \u00b5g" }, { "name": "Common", "value": "800 - 1000 \u00b5g" }, { "name": "Strong", "value": "1000 - 1200 \u00b5g" }, { "name": "Heavy", "value": null, "note": "The NBOMe series can be fatal at heavy doses.[4][5]" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "> 6 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Heavy", "value": null, "note": "The NBOMe series can be fatal when insufflated.[4][5][6] It is strongly discouraged." } ], "duration": null } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": [ "psychedelics" ] } }, { "url": "https://psychonautwiki.org/wiki/25I-NBOH", "name": "25I-NBOH", "aliases": [ "25i-NBOH", "Cimbi-27" ], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "200 - 500 \u00b5g" }, { "name": "Common", "value": "500 - 900 \u00b5g" }, { "name": "Strong", "value": "900 - 1400 \u00b5g" }, { "name": "Heavy", "value": null, "note": "25I-NBOH may be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "15 - 60 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "2 - 3.5 hours" }, { "name": "Offset", "value": "1.5 - 2.5 hours" }, { "name": "After effects", "value": "3 - 12 days" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "1 week", "zero": "2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/25I-NBOMe", "name": "25I-NBOMe", "aliases": [ "25i", "25i-NBOMe", "Cimbi-5" ], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "200 - 500 \u00b5g" }, { "name": "Common", "value": "500 - 700 \u00b5g" }, { "name": "Strong", "value": "700 - 1000 \u00b5g" }, { "name": "Heavy", "value": null, "note": "25I-NBOMe can be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "15 - 120 minutes" }, { "name": "Come up", "value": "30 - 120 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1 - 4 hours" }, { "name": "After effects", "value": "3 - 6 days" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "200 - 500 \u00b5g" }, { "name": "Common", "value": "500 - 700 \u00b5g" }, { "name": "Strong", "value": "700+ \u00b5g" }, { "name": "Heavy", "value": null, "note": "25I-NBOMe can be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Come up", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "60 - 120 minutes" }, { "name": "Offset", "value": "120 - 180 minutes" }, { "name": "After effects", "value": "1 - 7 days" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "1 week", "zero": "2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/25N-NBOMe", "name": "25N-NBOMe", "aliases": [], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "< 100 \u00b5g" }, { "name": "Light", "value": "100 - 300 \u00b5g" }, { "name": "Common", "value": "300 - 800 \u00b5g" }, { "name": "Strong", "value": "800 - 1300 \u03bcg" }, { "name": "Heavy", "value": null, "note": "The NBOMe series can be fatal at heavy doses.[4][5]" } ], "duration": [ { "name": "Total", "value": "5 - 10 hours" }, { "name": "Onset", "value": "45 - 75 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "5 - 10 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Heavy", "value": null, "note": "The NBOMe series can be fatal when insufflated.[4][5][6] It is strongly discouraged." } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "potentially fatal at heavy dosages" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-B", "name": "2C-B", "aliases": [ "Bees", "Nexus", "Tusi" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 45 mg" }, { "name": "Heavy", "value": "45 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "40 - 60 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1.5 - 3 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "non-addictive with a low potential for abuse", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/2C-B-FLY", "name": "2C-B-FLY", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 18 mg" }, { "name": "Strong", "value": "18 - 25 mg" }, { "name": "Heavy", "value": "25 mg +" } ], "duration": [ { "name": "Total", "value": "7 - 12 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines", "Substituted_benzofurans" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-C", "name": "2C-C", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "15 - 30 mg" }, { "name": "Common", "value": "30 - 50 mg" }, { "name": "Strong", "value": "50 - 90 mg" }, { "name": "Heavy", "value": "90 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "20 - 45 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "4 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/2C-D", "name": "2C-D", "aliases": [ "2C-M", "LE-25" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 50 mg" }, { "name": "Strong", "value": "50 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "0.5 - 1.5 hours" }, { "name": "After effects", "value": "1 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-E", "name": "2C-E", "aliases": [ "Aquarust", "Eternity" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "1 - 4 mg" }, { "name": "Common", "value": "4 - 7 mg" }, { "name": "Strong", "value": "7 - 14 mg" }, { "name": "Heavy", "value": "14 mg +" } ], "duration": [ { "name": "Onset", "value": "1 - 2 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-H", "name": "2C-H", "aliases": [ "DMPEA" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Common", "value": "??? -\u00a0???" } ], "duration": [ { "name": "Total", "value": "??? -\u00a0???" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Stimulants", "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3-5 days", "zero": "7-10 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-I", "name": "2C-I", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3-5 days", "zero": "7-10 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-P", "name": "2C-P", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 6 mg" }, { "name": "Common", "value": "6 - 10 mg" }, { "name": "Strong", "value": "10 - 16 mg" }, { "name": "Heavy", "value": "16 mg +" } ], "duration": [ { "name": "Total", "value": "10 - 20 hours" }, { "name": "Onset", "value": "1 - 3 hours" }, { "name": "Come up", "value": "2 - 4 hours" }, { "name": "Peak", "value": "4 - 8 hours" }, { "name": "Offset", "value": "3 - 6 hours" }, { "name": "After effects", "value": "8 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "low potential for abuse and dependence", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-T", "name": "2C-T", "aliases": [ "Tesseract" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 60 mg" }, { "name": "Common", "value": "60 - 100 mg" }, { "name": "Strong", "value": "100 - 120 mg" }, { "name": "Heavy", "value": "125 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "30 - 45 minutes" }, { "name": "Peak", "value": "30 - 115 minutes" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "no negative health effects attributed to trying this drug" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-T-2", "name": "2C-T-2", "aliases": [ "Rosy" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 30 mg" }, { "name": "Heavy", "value": "25 - 30 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2.5 - 5 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 25 mg" }, { "name": "Heavy", "value": "25+ mg" } ], "duration": [ { "name": "Total", "value": "3 - 7 hours" }, { "name": "Onset", "value": "5 - 15 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "no negative health effects attributed to trying this drug" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-T-21", "name": "2C-T-21", "aliases": [ "Aurora" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 12 mg" }, { "name": "Strong", "value": "12 - 15 mg" }, { "name": "Heavy", "value": "15 mg +" } ], "duration": [ { "name": "Total", "value": "10 - 12 hours" }, { "name": "Onset", "value": "90 - 120 minutes" }, { "name": "Peak", "value": "3 - 4 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": null, "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2C-T-7", "name": "2C-T-7", "aliases": [ "7th Heaven", "Beautiful", "Blue Mystic" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "60 - 90 minutes" }, { "name": "Come up", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "2 - 8 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 15 mg" }, { "name": "Heavy", "value": "15 - 25 mg", "note": "2C-T-7 has been fatal when insufflated at heavy doses of 30mg or higher." } ], "duration": [ { "name": "Total", "value": "3 - 7 hours" }, { "name": "Onset", "value": "5 - 15 minutes" }, { "name": "Come up", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": null, "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/2M2B", "name": "2M2B", "aliases": [ "2-methyl-2-butanol", "2m2b" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 mL" }, { "name": "Light", "value": "1 - 5 mL" }, { "name": "Common", "value": "5 - 10 mL" }, { "name": "Strong", "value": "10 - 15 mL" }, { "name": "Heavy", "value": "15 mL +", "note": "There have been unconsciousness and deaths reported at as low as 18 mL respective 29 mL." } ], "duration": [ { "name": "Total", "value": "8 - 14 hours" }, { "name": "Onset", "value": "10 - 50 minutes" }, { "name": "Peak", "value": "6 - 8 hours" }, { "name": "Offset", "value": "4 - 6 hours" }, { "name": "After effects", "value": "4 hours" } ] } ], "data": { "class": { "chemical": [ "Alcohol" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "GABA", "depressants" ] } }, { "url": "https://psychonautwiki.org/wiki/3,4-CTMP", "name": "3,4-CTMP", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 2 mg" }, { "name": "Light", "value": "2 - 4 mg" }, { "name": "Common", "value": "4 - 6 mg" }, { "name": "Heavy", "value": "6 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 18 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenidates" ], "psychoactive": [ "Stimulants" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/3-FA", "name": "3-FA", "aliases": [ "PAL-353" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "20 - 30 mg" }, { "name": "Common", "value": "30 - 50 mg" }, { "name": "Strong", "value": "50 - 70 mg" }, { "name": "Heavy", "value": "70 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 10 days" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/3-FEA", "name": "3-FEA", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "20 - 35 mg" }, { "name": "Common", "value": "35 - 70 mg" }, { "name": "Strong", "value": "70 - 90 mg" }, { "name": "Heavy", "value": "90 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 12 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "20 - 35 mg" }, { "name": "Common", "value": "35 - 60 mg" }, { "name": "Strong", "value": "50 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2 hours" }, { "name": "Onset", "value": "5 - 15 minutes" }, { "name": "Come up", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "30 - 60 minutes" }, { "name": "Offset", "value": "30 - 60 minutes" }, { "name": "After effects", "value": "1 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "2 - 3 days", "zero": "3-7 days" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "serotonin|serotonergic", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/3-FMA", "name": "3-FMA", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 35 mg" }, { "name": "Strong", "value": "35 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 7 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "6 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 10 days" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "serotonin|serotonergic", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/3-FPM", "name": "3-FPM", "aliases": [ "PAL-593" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "10 - 30 mg" }, { "name": "Common", "value": "30 - 60 mg" }, { "name": "Strong", "value": "60 - 90 mg" }, { "name": "Heavy", "value": "90 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "After effects", "value": "30 - 90 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 35 mg" }, { "name": "Strong", "value": "35 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "5 minutes" } ] } ], "data": { "class": { "chemical": [ "Phenylmorpholine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/3-HO-PCE", "name": "3-HO-PCE", "aliases": [ "Hydroxyeticyclidine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25 mg +", "note": "Redosing may result in dangerous cumulative effects." } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "4 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a moderate potential for adverse side effects such as psychosis", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/3-HO-PCP", "name": "3-HO-PCP", "aliases": [ "Hydroxyphencyclidine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 4 mg" }, { "name": "Common", "value": "4 - 6 mg" }, { "name": "Strong", "value": "6 - 8 mg" }, { "name": "Heavy", "value": "8 mg +", "note": "Redosing may result in dangerous cumulative effects." } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Come up", "value": "60 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "4 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for adverse side effects such as psychosis", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/3-MMC", "name": "3-MMC", "aliases": [ "Metaphedrone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "50 - 150 mg" }, { "name": "Common", "value": "150 - 250 mg" }, { "name": "Strong", "value": "250 - 350 mg" }, { "name": "Heavy", "value": "350 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "20 - 40 mg" }, { "name": "Common", "value": "40 - 60 mg" }, { "name": "Strong", "value": "60 - 120 mg" }, { "name": "Heavy", "value": "120 mg +" } ], "duration": [ { "name": "Total", "value": "2.5 - 4.5 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Come up", "value": "10 - 20 minutes" }, { "name": "Peak", "value": "1 - 1.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 1.5 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/3-MeO-PCE", "name": "3-MeO-PCE", "aliases": [ "Methoxyeticyclidine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "4 - 8 mg" }, { "name": "Common", "value": "8 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25+ mg", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "3 - 6 mg" }, { "name": "Common", "value": "6 - 12 mg" }, { "name": "Strong", "value": "12 - 20 mg" }, { "name": "Heavy", "value": "20 mg +", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "3 - 15 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "1.5 - 2 hours" }, { "name": "Offset", "value": "45 - 60 minutes" }, { "name": "After effects", "value": "4 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "toxic dosage is unknown" ], "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", "crossTolerances": [ "dissociatives" ] } }, { "url": "https://psychonautwiki.org/wiki/3-MeO-PCP", "name": "3-MeO-PCP", "aliases": [ "3-MeO" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 25 mg" }, { "name": "Heavy", "value": "25 mg +", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "45 - 120 minutes" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "4 - 8 mg" }, { "name": "Common", "value": "8 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25 mg +", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "45 - 120 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 15 mg" }, { "name": "Heavy", "value": "15 mg +", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "5 - 30 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "1.5 - 2 hours" }, { "name": "Offset", "value": "45 - 60 minutes" }, { "name": "After effects", "value": "4 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "toxic dosage is unknown" ], "addictionPotential": "produces dependence with chronic use and has a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/3C-E", "name": "3C-E", "aliases": [ "3C-Escaline" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "30 - 40 mg" }, { "name": "Common", "value": "40 - 60 mg" }, { "name": "Strong", "value": "60 - 80 mg" }, { "name": "Heavy", "value": "80 mg+" } ], "duration": [ { "name": "Total", "value": "10 - 16 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "Peak", "value": "4 - 8 hours" }, { "name": "Offset", "value": "3 - 6 hours" }, { "name": "After effects", "value": "3 - 6 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "20 - 35 mg" }, { "name": "Common", "value": "35 - 60 mg" }, { "name": "Strong", "value": "60 - 70 mg" }, { "name": "Heavy", "value": "70 mg+" } ], "duration": [ { "name": "Onset", "value": "5 - 90 minutes" }, { "name": "Peak", "value": "4 - 7 hours" }, { "name": "Offset", "value": "2 - 5 hours" }, { "name": "After effects", "value": "3 - 5 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-AcO-DET", "name": "4-AcO-DET", "aliases": [ "4-Acetoxy-DET", "Ethacetin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 20 mg" }, { "name": "Strong", "value": "20 - 35 mg" }, { "name": "Heavy", "value": "35 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 7 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "1 - 1.5 hours" }, { "name": "Peak", "value": "1.5 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-AcO-DMT", "name": "4-AcO-DMT", "aliases": [ "4-Acetoxy-DMT", "O-Acetylpsilocin", "Psilacetin", "Synthetic mushrooms" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "7.5 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 45 mg" }, { "name": "Heavy", "value": "45 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 7 hours" }, { "name": "Onset", "value": "15 - 40 minutes" }, { "name": "Come up", "value": "30 - 75 minutes" }, { "name": "Peak", "value": "2 - 3.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "5 - 25 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 hours - 1.5 hours" }, { "name": "After effects", "value": "2 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": null, "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "non-addictive with low potential for abuse", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-AcO-DiPT", "name": "4-AcO-DiPT", "aliases": [ "4-Acetoxy-DiPT", "Aces", "Ipracetin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 45 mg" }, { "name": "Heavy", "value": "45 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 4 hours" }, { "name": "Onset", "value": "15 - 40 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1.5 - 2 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-AcO-MET", "name": "4-AcO-MET", "aliases": [ "4-Acetoxy-MET", "Metacetin", "O-Acetylmetocin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "2 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-AcO-MiPT", "name": "4-AcO-MiPT", "aliases": [ "Mipracetin", "O-Acetylmiprocin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 20 mg" }, { "name": "Strong", "value": "20 - 35 mg" }, { "name": "Heavy", "value": "35 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "1.5 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-FA", "name": "4-FA", "aliases": [ "4-FMP", "Flux", "PAL-303" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "40 mg" }, { "name": "Light", "value": "40 - 100 mg" }, { "name": "Common", "value": "100 - 130 mg" }, { "name": "Strong", "value": "130 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "45 - 75 minutes" }, { "name": "Come up", "value": "30 - 75 minutes" }, { "name": "Peak", "value": "2.5 - 3.5 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulants" ] } }, { "url": "https://psychonautwiki.org/wiki/4-FMA", "name": "4-FMA", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "25 - 50 mg" }, { "name": "Common", "value": "50 - 75 mg" }, { "name": "Strong", "value": "100 - 125 mg" }, { "name": "Heavy", "value": "125 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "2 - 5 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "3 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/4-HO-DET", "name": "4-HO-DET", "aliases": [ "CZ-74", "Ethocin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "20 - 30 mg" }, { "name": "Strong", "value": "30 - 45 mg" }, { "name": "Heavy", "value": "45 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 7 hours" }, { "name": "Onset", "value": "20 - 45 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2.5 - 3.5 hours" }, { "name": "Offset", "value": "1.5 - 2 hours" }, { "name": "After effects", "value": "1 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-HO-DPT", "name": "4-HO-DPT", "aliases": [ "Procin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 60 mg" }, { "name": "Common", "value": "60 - 90 mg" }, { "name": "Strong", "value": "90 - 130 mg" }, { "name": "Heavy", "value": "130 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "45 - 60 minutes" }, { "name": "Come up", "value": "60 - 120 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 35 mg" }, { "name": "Heavy", "value": "35 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "30 - 45 minutes" }, { "name": "Peak", "value": "1 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-HO-DiPT", "name": "4-HO-DiPT", "aliases": [ "Iprocin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "3 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "30 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-HO-EPT", "name": "4-HO-EPT", "aliases": [ "Eprocin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Common", "value": "25 - 50 mg" } ], "duration": [ { "name": "Total", "value": "3 - 7 hours" }, { "name": "Onset", "value": "30 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-HO-MET", "name": "4-HO-MET", "aliases": [ "Colour", "Methylcybin", "Metocin" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 35 mg" }, { "name": "Strong", "value": "35 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "25 - 45 minutes" }, { "name": "Onset", "value": "15 - 120 seconds" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 45 mg" }, { "name": "Heavy", "value": "45 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "15 - 40 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-HO-MPT", "name": "4-HO-MPT", "aliases": [ "Meprocin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 7 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-HO-MiPT", "name": "4-HO-MiPT", "aliases": [ "Miprocin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 35 mg" }, { "name": "Heavy", "value": "35 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/4-MeO-PCP", "name": "4-MeO-PCP", "aliases": [ "Methoxydine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "75 - 100 mg" }, { "name": "Common", "value": "100 - 170 mg" }, { "name": "Strong", "value": "170 - 250 mg" }, { "name": "Heavy", "value": "250 mg +" } ], "duration": [ { "name": "Total", "value": "12 - 20 hours" }, { "name": "Onset", "value": "45 - 120 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "3 - 7 hours" }, { "name": "Offset", "value": "6 - 10 hours" }, { "name": "After effects", "value": "6+ hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "30 - 75 mg" }, { "name": "Common", "value": "75 - 150 mg" }, { "name": "Strong", "value": "150mg +" } ], "duration": [ { "name": "Total", "value": "12 - 18 hours" }, { "name": "Onset", "value": "5 - 15 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "3 - 6 hours" }, { "name": "Offset", "value": "3 hours" }, { "name": "After effects", "value": "3 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/4F-EPH", "name": "4F-EPH", "aliases": [ "4FEPH" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 6 hours" }, { "name": "Onset", "value": "10 - 25 minutes" }, { "name": "After effects", "value": "4 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenidates" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/4F-MPH", "name": "4F-MPH", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "5 - 10 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 8 mg" }, { "name": "Common", "value": "8 - 14 mg" }, { "name": "Strong", "value": "14 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenidates" ], "psychoactive": [ "Stimulants" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/5-APB", "name": "5-APB", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 60 mg" }, { "name": "Common", "value": "60 - 80 mg" }, { "name": "Strong", "value": "80 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1.5 - 3 hours" }, { "name": "After effects", "value": "6 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_benzofurans", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/5-Hydroxytryptophan", "name": "5-Hydroxytryptophan", "aliases": [ "5-HTP", "Cincofarm", "Levothym", "Levotonine", "Oxitriptan", "Oxyfan", "Telesol", "Tript-OH", "and Triptum" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 300 mg" }, { "name": "Strong", "value": "300 - 500 mg" }, { "name": "Heavy", "value": "500 mg +" } ], "duration": null } ], "data": { "class": { "chemical": [ "Amino_acid", "Substituted_tryptamines" ], "psychoactive": [ "Nootropic" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/5-MAPB", "name": "5-MAPB", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 60 mg" }, { "name": "Common", "value": "60 - 80 mg" }, { "name": "Strong", "value": "80 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1.5 - 3 hours" }, { "name": "After effects", "value": "6 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_benzofurans", "Substituted_amphetamines" ], "psychoactive": [ "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/5-MeO-DALT", "name": "5-MeO-DALT", "aliases": [ "Foxtrot" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Common", "value": "5 - 10 mg" } ], "duration": [ { "name": "Total", "value": "15 - 20 minutes" }, { "name": "Onset", "value": "15 - 60 seconds" }, { "name": "Peak", "value": "1 - 5 minutes" }, { "name": "Offset", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "5 - 10 minutes" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "4 mg" }, { "name": "Light", "value": "5 - 12 mg" }, { "name": "Common", "value": "12 - 25 mg" }, { "name": "Strong", "value": "25 - 35 mg" }, { "name": "Heavy", "value": "35 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/5-MeO-DMT", "name": "5-MeO-DMT", "aliases": [ "The God Molecule" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "3 - 6 mg" }, { "name": "Common", "value": "6 - 12 mg" }, { "name": "Strong", "value": "12 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "20 - 40 minutes" }, { "name": "Onset", "value": "5 - 60 seconds" }, { "name": "Come up", "value": "30 - 60 seconds" }, { "name": "Peak", "value": "5 - 15 minutes" }, { "name": "Offset", "value": "10 - 20 minutes" }, { "name": "After effects", "value": "15 - 60 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "5 - 8 mg" }, { "name": "Common", "value": "8 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25mg+" } ], "duration": [ { "name": "Total", "value": "2 - 3 hours" }, { "name": "Onset", "value": "1 - 10 minutes" }, { "name": "Peak", "value": "10 - 40 minutes" }, { "name": "Offset", "value": "30 - 60 minutes" }, { "name": "After effects", "value": "1 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "1 hour", "zero": "2 hours" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "non-addictive with a low abuse potential", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/5-MeO-DiBF", "name": "5-MeO-DiBF", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "50 - 80 mg" }, { "name": "Common", "value": "80 - 110 mg" }, { "name": "Strong", "value": "110 - 140 mg" }, { "name": "Heavy", "value": "140 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Peak", "value": "30 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_benzofurans" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/5-MeO-DiPT", "name": "5-MeO-DiPT", "aliases": [ "Foxy", "Foxy Methoxy" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "3 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/5-MeO-MiPT", "name": "5-MeO-MiPT", "aliases": [ "Moxy" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 3 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "3 - 7 mg" }, { "name": "Common", "value": "7 - 15 mg" }, { "name": "Strong", "value": "15 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics", "Entactogens" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/5F-AKB48", "name": "5F-AKB48", "aliases": [ "5F-APINACA" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "0.5 - 1 mg" }, { "name": "Common", "value": "1 - 2 mg" }, { "name": "Strong", "value": "2 - 4 mg" }, { "name": "Heavy", "value": "4 mg +" } ], "duration": [ { "name": "Total", "value": "30 - 60 minutes" }, { "name": "Onset", "value": "0 - 20 minutes" }, { "name": "Peak", "value": "10 - 30 minutes" }, { "name": "Offset", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "15 - 30 minutes" } ] } ], "data": { "class": { "chemical": [ "Adamantanes", "Indazolecarboxamide" ], "psychoactive": [ "Cannabinoid" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "cannabinoids" ] } }, { "url": "https://psychonautwiki.org/wiki/6-APB", "name": "6-APB", "aliases": [ "Benzofury" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "30 - 60 mg" }, { "name": "Common", "value": "60 - 90 mg" }, { "name": "Strong", "value": "90 - 120 mg" }, { "name": "Heavy", "value": "120 mg +" } ], "duration": [ { "name": "Total", "value": "7 - 10 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Come up", "value": "60 - 120 minutes" }, { "name": "Peak", "value": "3 - 4 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_benzofurans", "Substituted_amphetamines" ], "psychoactive": [ "Psychedelics", "Entactogens" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "3-4 weeks", "zero": "6-8 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/6-APDB", "name": "6-APDB", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "30 - 70 mg" }, { "name": "Common", "value": "70 - 100 mg" }, { "name": "Strong", "value": "100 - 130 mg" }, { "name": "Heavy", "value": "130 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 8 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "2 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines", "Substituted_benzofurans", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "21-30 days", "zero": "2-3 months" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/A-PHP", "name": "A-PHP", "aliases": [ "PV7", "alpha-PHP", "\u03b1-PHP" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 20 mg" }, { "name": "Heavy", "value": "20+ mg" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "2 - 8 minutes" }, { "name": "Peak", "value": "30 - 90 minutes" }, { "name": "Offset", "value": "1 - 4 hours" }, { "name": "After effects", "value": "1 - 8 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 8 hours" }, { "name": "Onset", "value": "2 - 20 minutes" }, { "name": "Peak", "value": "1 - 2.5 hours" }, { "name": "Offset", "value": "1 - 5 hours" }, { "name": "After effects", "value": "1 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "1 - 5 mg" }, { "name": "Common", "value": "5 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25+ mg" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "20 - 45 minutes" }, { "name": "Offset", "value": "30 - 90 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Pyrrolidinophenone", "Substituted_cathinones" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "highly addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/A-PVP", "name": "A-PVP", "aliases": [ "Flakka", "O-2387", "Prolintanone", "alpha-PVP", "\u03b1-PVP", "\u03b2-ketone-prolintane" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 5 mg" }, { "name": "Common", "value": "5 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25 mg +" } ], "duration": [ { "name": "Total", "value": "30 - 60 minutes" }, { "name": "Onset", "value": "20 - 60 seconds" }, { "name": "Peak", "value": "3 - 6 minutes" }, { "name": "Offset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "1 - 3 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 6 hours" }, { "name": "Onset", "value": "2 - 20 minutes" }, { "name": "Peak", "value": "1 - 2.5 hours" }, { "name": "Offset", "value": "1 - 5 hours" }, { "name": "After effects", "value": "4 - 12 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "1 - 5 mg" }, { "name": "Common", "value": "5 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "20 - 45 minutes" }, { "name": "Offset", "value": "30 - 90 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Pyrrolidinophenone", "Substituted_cathinones" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "highly addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/AB-FUBINACA", "name": "AB-FUBINACA", "aliases": [ "Ab-fubi" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "< 1 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 3 mg" }, { "name": "Strong", "value": "3 - 5 mg" }, { "name": "Heavy", "value": "5 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2 hours" }, { "name": "Onset", "value": "0 - 20 minutes" }, { "name": "Peak", "value": "30 - 60 minutes" }, { "name": "Offset", "value": "10 - 20 minutes" }, { "name": "After effects", "value": "15 - 30 minutes" } ] } ], "data": { "class": { "chemical": [ "Indazolecarboxamide" ], "psychoactive": [ "Cannabinoid" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "cannabinoids" ] } }, { "url": "https://psychonautwiki.org/wiki/AL-LAD", "name": "AL-LAD", "aliases": [ "Aladdin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 \u00b5g" }, { "name": "Light", "value": "50 - 100 \u00b5g" }, { "name": "Common", "value": "100 - 225 \u00b5g" }, { "name": "Strong", "value": "225 - 350 \u00b5g" }, { "name": "Heavy", "value": "350 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "7 - 10 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2.5 - 5 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "2 - 18 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "toxic dose is unknown", "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/ALD-52", "name": "ALD-52", "aliases": [ "1-Acetyl-LSD", "1A-LAD", "1A-LSD", "Orange Sunshine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "30 \u00b5g" }, { "name": "Light", "value": "30 - 100 \u00b5g" }, { "name": "Common", "value": "100 - 175 \u00b5g" }, { "name": "Strong", "value": "175 - 325 \u00b5g" }, { "name": "Heavy", "value": "325 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "8 - 14 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "3 - 5 hours" }, { "name": "After effects", "value": "4 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "toxic dose is unknown", "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/APICA", "name": "APICA", "aliases": [ "2NE1", "SDB-001" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "< 0.5 mg" }, { "name": "Light", "value": "0.5 - 1.5 mg" }, { "name": "Common", "value": "1.5 - 2 mg" }, { "name": "Strong", "value": "2 - 4 mg" }, { "name": "Heavy", "value": "4 mg +" } ], "duration": [ { "name": "Total", "value": "30 - 60 minutes" }, { "name": "Onset", "value": "0 - 20 seconds" }, { "name": "Peak", "value": "10 - 30 minutes" }, { "name": "Offset", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "15 - 35 minutes" } ] } ], "data": { "class": { "chemical": [ "Indole_cannabinoid", "Indolecarboxamide" ], "psychoactive": [ "Cannabinoid" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "cannabinoids" ] } }, { "url": "https://psychonautwiki.org/wiki/Acetylfentanyl", "name": "Acetylfentanyl", "aliases": [], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 4 hours" }, { "name": "Onset", "value": "20 - 40 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 4 hours" }, { "name": "Onset", "value": "7 - 10 minutes" } ] } ], "data": { "class": { "chemical": [ "Anilidopiperidine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages", "potentially lethal when mixed with depressants like alcohol or benzodiazepines", "unintentionally spilling a very small amount of acetylfentanyl on one's skin could result in a fatal overdose." ], "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Adrafinil", "name": "Adrafinil", "aliases": [ "Olmifon" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "100 mg" }, { "name": "Light", "value": "150 - 250 mg" }, { "name": "Common", "value": "250 - 400 mg" }, { "name": "Strong", "value": "400 - 600 mg" }, { "name": "Heavy", "value": "600 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 12 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "Come up", "value": "45 - 60 minutes" }, { "name": "Peak", "value": "4.5 - 6 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": null, "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "not addictive with a low potential for abuse", "crossTolerances": [ "benzhydryl", "nootropic|nootropics" ] } }, { "url": "https://psychonautwiki.org/wiki/Allylescaline", "name": "Allylescaline", "aliases": [ "AL" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "20 - 30 mg" }, { "name": "Common", "value": "30 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "45 - 240 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Alpha-GPC", "name": "Alpha-GPC", "aliases": [ "L-Alpha glycerylphosphorylcholine", "alpha-GPC", "choline alfoscerate" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "100 - 300 mg" }, { "name": "Common", "value": "300 - 500 mg" }, { "name": "Strong", "value": "500 - 1000 mg" }, { "name": "Heavy", "value": "1000 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "45 - 75 minutes" } ] } ], "data": { "class": { "chemical": [ "Choline_derivative" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "after prolonged and repeated usage", "half": "7 days", "zero": "14 days" }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [] } }, { "url": "https://psychonautwiki.org/wiki/Alprazolam", "name": "Alprazolam", "aliases": [ "Xanax" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.10 mg" }, { "name": "Light", "value": "0.25 - 0.5 mg" }, { "name": "Common", "value": "0.5 - 1.5 mg" }, { "name": "Strong", "value": "1.5 - 2 mg" }, { "name": "Heavy", "value": "2 - 3 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "2 - 6 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7-14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Amanita_muscaria", "name": "Amanita muscaria", "aliases": [ "Fly agaric", "Fly amanita" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Amphetamine", "name": "Amphetamine", "aliases": [ "Adderall", "Pep", "Speed" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "7.5 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 70 mg" }, { "name": "Heavy", "value": "70 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 8 hours" }, { "name": "Onset", "value": "30 - 45 minutes" }, { "name": "Come up", "value": "30 - 135 minutes" }, { "name": "Peak", "value": "2.5 - 4 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "3 - 6 hours" } ], "bioavailability": "75%+" }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "4 mg" }, { "name": "Light", "value": "6 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "1 - 5 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1.5 - 3 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "has a high abuse potential and can cause dependence with chronic use", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Anadenanthera_peregrina", "name": "Anadenanthera peregrina", "aliases": [ "Cohoba", "Jopo", "Yopo" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Aniracetam", "name": "Aniracetam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "350 mg" }, { "name": "Light", "value": "500 - 1200 mg" }, { "name": "Common", "value": "1200 - 1800 mg" }, { "name": "Strong", "value": "1800 - 2400 mg" }, { "name": "Heavy", "value": "2400 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "45 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Racetams" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "non-addictive with a low potential for abuse", "crossTolerances": [ "racetam", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Armodafinil", "name": "Armodafinil", "aliases": [ "Artvigil", "Neoresotyl", "Nuvigil", "R-Modawake", "Waklert" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 100 mg" }, { "name": "Common", "value": "100 - 200 mg" }, { "name": "Strong", "value": "200 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 15 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "1 - 2.5 hours" }, { "name": "Peak", "value": "4 - 7 hours" }, { "name": "Offset", "value": "2 - 5 hours" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Benzhydryl" ], "psychoactive": [ "Eugeroic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "The median lethal dose at which 50% of participants die (LD50) from either armodafinil or modafinil for human beings has never been reached" ], "addictionPotential": "mildly addictive with a low potential for abuse", "crossTolerances": [ "benzhydryl", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Atropa_belladonna", "name": "Atropa belladonna", "aliases": [ "Belladonna", "Deadly nightshade" ], "roas": [], "data": { "class": { "chemical": [ "Substituted_tropanes" ], "psychoactive": [ "Deliriant" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Ayahuasca", "name": "Ayahuasca", "aliases": [ "Aya", "Caapi", "Cip\u00f3", "Hoasca", "Natem", "Shori", "Vegetal", "Yag\u00e9", "Yaj\u00e9" ], "roas": [ { "name": "Oral", "dosage": null, "duration": [ { "name": "Total", "value": "5 - 10 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 8 hours" } ] } ], "data": { "class": { "chemical": null, "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": [ "LD50 is around 50 times a regular dose" ], "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Banisteriopsis_caapi", "name": "Banisteriopsis caapi", "aliases": [ "Ayahuasca", "Caapi or Yag\u00e9" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Bromantane", "name": "Bromantane", "aliases": [ "Bromantan", "Ladasten" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 10 mg" }, { "name": "Light", "value": "10 - 50 mg" }, { "name": "Common", "value": "50 - 100 mg" }, { "name": "Strong", "value": "100 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 4 hours" } ], "bioavailability": "42%" } ], "data": { "class": { "chemical": [ "Adamantanes" ], "psychoactive": null }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Bromo-DragonFLY", "name": "Bromo-DragonFLY", "aliases": [ "B-DFLY", "DOB-DragonFLY", "Dragonfly" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "75 \u00b5g" }, { "name": "Light", "value": "100 - 300 \u00b5g" }, { "name": "Common", "value": "300 - 500 \u00b5g" }, { "name": "Strong", "value": "500 - 750 \u00b5g" }, { "name": "Heavy", "value": "750 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "1 - 4 days" }, { "name": "Onset", "value": "2 - 7 hours" }, { "name": "Come up", "value": "3 - 6 hours" }, { "name": "Peak", "value": "6 - 12 hours" }, { "name": "Offset", "value": "3 - 8 hours" }, { "name": "After effects", "value": "12 - 36 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_benzofurans", "Substituted_amphetamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "6 days", "zero": "14 days" }, "toxicity": [ "extreme vasoconstrictive effects", "one can easily overdose if this substance is not measured correctly", "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Bufotenin", "name": "Bufotenin", "aliases": [ "5-HO-DMT" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "15 - 90 minutes" }, { "name": "Onset", "value": "15 - 60 seconds" }, { "name": "Peak", "value": "1 - 5 minutes" }, { "name": "Offset", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "10 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "1 hour", "zero": "2 hours" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Buprenorphine", "name": "Buprenorphine", "aliases": [ "Addnok", "Buprenex", "Butrans", "Cizdol", "Subutex", "Transtec" ], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "<0.3 mg" }, { "name": "Light", "value": "0.3 - 0.6 mg" }, { "name": "Common", "value": "0.6 - 1.3 mg" }, { "name": "Strong", "value": "1.3 - 2.4 mg" }, { "name": "Heavy", "value": "2.4 mg +" } ], "duration": [ { "name": "Total", "value": "10 - 18 hours" }, { "name": "Onset", "value": "40 - 80 minutes" }, { "name": "Peak", "value": "4 - 8 hours" }, { "name": "After effects", "value": "1 - 3 days" } ], "bioavailability": "30%" }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "< 0.2 mg" }, { "name": "Light", "value": "0.2 - 0.4 mg" }, { "name": "Common", "value": "0.4 - 0.8 mg" }, { "name": "Strong", "value": "0.8 - 1.5 mg" }, { "name": "Heavy", "value": "1.5 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 14 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "4 - 8 hours" }, { "name": "After effects", "value": "1 - 3 days" } ], "bioavailability": "48%" } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Butylone", "name": "Butylone", "aliases": [ "B1", "bk-MBDB" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 80 mg" }, { "name": "Common", "value": "80 - 125 mg" }, { "name": "Strong", "value": "125 - 225 mg" }, { "name": "Heavy", "value": "225 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "15 - 60 minutes" }, { "name": "Peak", "value": "60 - 120 minutes" }, { "name": "Offset", "value": "60 - 120 minutes" }, { "name": "After effects", "value": "4 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "MDxx", "Substituted_cathinones" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Caffeine", "name": "Caffeine", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "20 - 50 mg" }, { "name": "Common", "value": "50 - 150 mg" }, { "name": "Strong", "value": "150 - 500 mg" }, { "name": "Heavy", "value": "500 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Come up", "value": "10 - 60 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "6 - 10 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "2.5 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 40 mg" }, { "name": "Strong", "value": "40 - 80 mg" }, { "name": "Heavy", "value": "80 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2.5 hours" }, { "name": "Onset", "value": "0.5 - 2 minutes" }, { "name": "Come up", "value": "0.5 - 2 minutes" }, { "name": "Peak", "value": "0.5 - 1 hours" }, { "name": "Offset", "value": "6 - 10 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Xanthines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "The LD50 of caffeine in humans is dependent on individual sensitivity, but is estimated to be about 150 to 200 milligrams per kilogram of body mass or roughly 80 to 100 cups of coffee for an average adult" ], "addictionPotential": "produces dependence with chronic use and has a low abuse potential", "crossTolerances": [] } }, { "url": "https://psychonautwiki.org/wiki/Cake", "name": "Cake", "aliases": [ "Caky", "Cokoo" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25g-30g" }, { "name": "Light", "value": "30g-65g" }, { "name": "Common", "value": "65g-100g" }, { "name": "Strong", "value": "100g-300g" }, { "name": "Heavy", "value": "300g-500g" } ], "duration": null, "bioavailability": "90%" } ], "data": { "class": { "chemical": null, "psychoactive": [ "Depressant" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Cannabidiol", "name": "Cannabidiol", "aliases": [ "CBD", "Epidiolex" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "1.5 - 4 hours" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Offset", "value": "1 - 1.5 hours" } ] } ], "data": { "class": { "chemical": [ "Cannabinoid" ], "psychoactive": null }, "tolerance": null, "toxicity": [ "well-tolerated and shows little to no toxicity" ], "addictionPotential": "low abuse potential", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Cannabis", "name": "Cannabis", "aliases": [ "Bud", "Grass", "Green", "Herb", "Marijuana", "Mary Jane", "Pot", "Tree", "Weed" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "33 - 66 mg" }, { "name": "Common", "value": "66 - 100 mg" }, { "name": "Strong", "value": "100 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 4 hours" }, { "name": "Onset", "value": "0 - 10 minutes" }, { "name": "Come up", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "45 - 180 minutes" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg (THC)" }, { "name": "Light", "value": "2.5 - 5 mg (THC)" }, { "name": "Common", "value": "5 - 10 mg (THC)" }, { "name": "Strong", "value": "10 - 25 mg (THC)" }, { "name": "Heavy", "value": "25 mg + (THC)" } ], "duration": [ { "name": "Total", "value": "4 - 10 hours" }, { "name": "Onset", "value": "20 - 120 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "2 - 5 hours" }, { "name": "After effects", "value": "6 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Cannabinoid" ], "psychoactive": null }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "1 - 2 weeks", "zero": "2 - 3 weeks" }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "moderately habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Carisoprodol", "name": "Carisoprodol", "aliases": [ "Soma" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "100 - 325 mg" }, { "name": "Common", "value": "325 - 500 mg" }, { "name": "Strong", "value": "500 - 750 mg" }, { "name": "Heavy", "value": "750 mg +" } ], "duration": [ { "name": "Onset", "value": "15 - 60 minutes" }, { "name": "Peak", "value": "2 - 5 hours" }, { "name": "After effects", "value": "1 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Carbamate" ], "psychoactive": [ "Depressant" ] }, "tolerance": null, "toxicity": [ "moderate toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Choline_bitartrate", "name": "Choline bitartrate", "aliases": [ "Choline" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "100 - 250 mg" }, { "name": "Common", "value": "250 - 1000 mg" }, { "name": "Strong", "value": "1000 - 2000 mg" }, { "name": "Heavy", "value": "2000 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "45 - 75 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 8 hours" } ], "bioavailability": "40%" } ], "data": { "class": { "chemical": [ "Ammonium_salt" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "after prolonged and repeated usage", "half": "7 days", "zero": "14 days" }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [] } }, { "url": "https://psychonautwiki.org/wiki/Citicoline", "name": "Citicoline", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "100 - 250 mg" }, { "name": "Common", "value": "250 - 1000 mg" }, { "name": "Strong", "value": "1000 - 2000 mg" }, { "name": "Heavy", "value": "2000 mg +" } ], "duration": [ { "name": "Total", "value": "58 - 74 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "Come up", "value": "2 - 3 hours" }, { "name": "Peak", "value": "2.5 - 3.5 hours" }, { "name": "Offset", "value": "30 - 40 hours" }, { "name": "After effects", "value": "40 - 60 hours" } ], "bioavailability": "98%" } ], "data": { "class": { "chemical": [ "Ammonium_salt" ], "psychoactive": [ "Nootropic" ] }, "tolerance": null, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Clonazepam", "name": "Clonazepam", "aliases": [ "K-Pins", "Klonopin", "Rivotril" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.10 mg" }, { "name": "Light", "value": "0.25 - 0.5 mg" }, { "name": "Common", "value": "0.5 - 1 mg" }, { "name": "Strong", "value": "1 - 2 mg" }, { "name": "Heavy", "value": "2 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "After effects", "value": "8 - 48 hours" } ], "bioavailability": "90%" } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Clonazolam", "name": "Clonazolam", "aliases": [ "Clonitrazolam" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "75 - 200 \u00b5g" }, { "name": "Common", "value": "200 - 400 \u00b5g" }, { "name": "Strong", "value": "400 - 1 mg" }, { "name": "Heavy", "value": "1 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "10 - 30 minutes" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Clonidine", "name": "Clonidine", "aliases": [ "Catapres", "Catapres-TTS", "Kapvay", "Nexiclon XR" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 \u03bcg" }, { "name": "Light", "value": "50 - 75 \u03bcg" }, { "name": "Common", "value": "75 - 100 \u03bcg" }, { "name": "Strong", "value": "100 - 300 \u03bcg" }, { "name": "Heavy", "value": "300 \u03bcg +" } ], "duration": [ { "name": "Total", "value": "6 - 8 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "6 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Imidazoline" ], "psychoactive": [ "Depressant" ] }, "tolerance": null, "toxicity": null, "addictionPotential": "not addictive and has a low potential for abuse", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Cocaine", "name": "Cocaine", "aliases": [ "Blow", "Coke", "Crack", "Girl", "Nose Candy", "Snow", "White" ], "roas": [ { "name": "Inhaled", "dosage": null, "duration": null }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 30 mg" }, { "name": "Common", "value": "30 - 60 mg" }, { "name": "Strong", "value": "60 - 90 mg" }, { "name": "Heavy", "value": "90 mg +" } ], "duration": [ { "name": "Total", "value": "10 - 90 minutes" }, { "name": "Onset", "value": "1 - 10 minutes" }, { "name": "Come up", "value": "5 - 15 minutes" }, { "name": "Peak", "value": "15 - 30 minutes" }, { "name": "Offset", "value": "10 - 30 minutes" } ], "bioavailability": "60-80%" } ], "data": { "class": { "chemical": [ "Substituted_tropanes" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "individuals have died from as little as 30 mg applied to mucous membranes, whereas addicts may tolerate up to 5 grams daily" ], "addictionPotential": "highly addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Codeine", "name": "Codeine", "aliases": [], "roas": [ { "name": "Smoked", "dosage": null, "duration": null, "bioavailability": "49.9 - 59.7%" }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "30 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 150 mg" }, { "name": "Strong", "value": "150 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "30 - 45 minutes" }, { "name": "Come up", "value": "1 - 2 hours" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Coluracetam", "name": "Coluracetam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "3 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "15 - 30 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "1 - 5 minutes" } ] } ], "data": { "class": { "chemical": [ "Racetams" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "not addictive with a low potential for abuse", "crossTolerances": [ "racetam", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Creatine", "name": "Creatine", "aliases": [ "Methylguanidoacetic acid", "N-Carbamimidoyl-N-methylglycine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.25 g" }, { "name": "Light", "value": "1 - 5 g" }, { "name": "Common", "value": "5 - 10 g" }, { "name": "Strong", "value": "10 - 20 g" }, { "name": "Heavy", "value": "20 g +" } ], "duration": [ { "name": "Total", "value": "30 - 36 hours" }, { "name": "Onset", "value": "30 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Nitrogenous_organic_acid" ], "psychoactive": [ "Nootropic" ] }, "tolerance": null, "toxicity": null, "addictionPotential": "not habit-forming with a low potential for abuse", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Cyclazodone", "name": "Cyclazodone", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +", "note": "Liver damage may result from heavy or sustained usage." } ], "duration": [ { "name": "Total", "value": "5 - 7 hours" }, { "name": "Onset", "value": "20 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "4-oxazolidinone", "Substituted_aminorexes" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": null, "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/DET", "name": "DET", "aliases": [ "Diethyltryptamine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "20 - 40 mg" }, { "name": "Common", "value": "40 - 70 mg" }, { "name": "Strong", "value": "70 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "After effects", "value": "2 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/DMT", "name": "DMT", "aliases": [ "Dmitry", "N,N-DMT", "The Glory", "The Spirit Molecule" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60+ mg" } ], "duration": [ { "name": "Total", "value": "5 - 20 minutes" }, { "name": "Onset", "value": "20 - 40 seconds" }, { "name": "Come up", "value": "1 - 3 minutes" }, { "name": "Peak", "value": "2 - 8 minutes" }, { "name": "Offset", "value": "1 - 6 minutes" }, { "name": "After effects", "value": "10 - 60 minutes" } ] }, { "name": "Intravenous", "dosage": [ { "name": "Threshold", "value": "4 mg" }, { "name": "Light", "value": "4 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "15 - 30 minutes" }, { "name": "Onset", "value": "2 - 10 seconds" }, { "name": "Come up", "value": "-" }, { "name": "Peak", "value": "2 - 5 minutes" }, { "name": "Offset", "value": "-" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "does not appear to occur", "half": null, "zero": null }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "non-addictive with a low abuse potential", "crossTolerances": [ "psychedelics" ] } }, { "url": "https://psychonautwiki.org/wiki/DOB", "name": "DOB", "aliases": [ "Brolamfetamine", "Bromo-DMA" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.2 mg" }, { "name": "Light", "value": "0.2 - 0.75 mg" }, { "name": "Common", "value": "0.75 - 1.75 mg" }, { "name": "Strong", "value": "1.75 - 3 mg" }, { "name": "Heavy", "value": "3 mg +" } ], "duration": [ { "name": "Total", "value": "14 - 24 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "2 - 4 hours" }, { "name": "Peak", "value": "6 - 10 hours" }, { "name": "Offset", "value": "4 - 8 hours" }, { "name": "After effects", "value": "4 - 16 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "4-7 days", "zero": "7-10 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/DOC", "name": "DOC", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 4 mg" }, { "name": "Strong", "value": "4 - 6 mg" }, { "name": "Heavy", "value": "6 mg +" } ], "duration": [ { "name": "Total", "value": "12 - 24 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "Come up", "value": "2 - 3 hours" }, { "name": "Peak", "value": "6 - 12 hours" }, { "name": "Offset", "value": "2 - 8 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "0.25 mg" }, { "name": "Light", "value": "0.25 - 1 mg" }, { "name": "Common", "value": "1 - 2 mg" }, { "name": "Strong", "value": "2 - 3.5 mg" }, { "name": "Heavy", "value": "3.5 mg +" } ], "duration": [ { "name": "Onset", "value": "1 - 5 minutes" }, { "name": "Come up", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "2 - 6 hours" }, { "name": "Offset", "value": "2 - 8 hours" }, { "name": "After effects", "value": "2 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/DOI", "name": "DOI", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "0.5 - 1 mg" }, { "name": "Common", "value": "1 - 2 mg" }, { "name": "Strong", "value": "2 - 3 mg" }, { "name": "Heavy", "value": "3 mg +" } ], "duration": [ { "name": "Total", "value": "16 - 24 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "Come up", "value": "1.5 - 3 hours" }, { "name": "Peak", "value": "6 - 10 hours" }, { "name": "Offset", "value": "4 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "10-14 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/DOM", "name": "DOM", "aliases": [ "STP (Serenity", "Tranquility", "and Peace)" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "1 - 3 mg" }, { "name": "Common", "value": "3 - 5 mg" }, { "name": "Strong", "value": "5 - 10 mg" }, { "name": "Heavy", "value": "10 mg +" } ], "duration": [ { "name": "Total", "value": "12 - 16 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "Come up", "value": "2 - 3 hours" }, { "name": "Peak", "value": "6 - 8 hours" }, { "name": "Offset", "value": "3 - 5 hours" }, { "name": "After effects", "value": "4 - 16 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/DPT", "name": "DPT", "aliases": [ "Dipropyltryptamine", "The Light" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "15 - 20 mg" }, { "name": "Common", "value": "20 - 50 mg" }, { "name": "Strong", "value": "50 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Total", "value": "30 - 90 minutes" }, { "name": "Onset", "value": "0 - 1 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "75 - 150 mg" }, { "name": "Common", "value": "150 - 250 mg" }, { "name": "Strong", "value": "250 - 350 mg" }, { "name": "Heavy", "value": "350 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "After effects", "value": "2 - 3 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "20 - 50 mg" }, { "name": "Common", "value": "50 - 100 mg" }, { "name": "Strong", "value": "100 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "5 - 20 minutes" }, { "name": "Peak", "value": "30 - 46 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Datura", "name": "Datura", "aliases": [ "Jimson Weed" ], "roas": [ { "name": "Oral", "dosage": null, "duration": [ { "name": "Total", "value": "8 - 18 hours" }, { "name": "Onset", "value": "20 - 120 minutes" }, { "name": "Come up", "value": "60 - 120 minutes" }, { "name": "Peak", "value": "5 - 12 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": null, "psychoactive": [ "Deliriant" ] }, "tolerance": { "full": "with repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "toxic dosage is unknown" ], "addictionPotential": "mildly addictive with a high potential for adverse side effects such as psychosis", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Datura_(botany)", "name": "Datura (botany)", "aliases": [ "Jimsonweed", "angel's trumpets", "devil's trumpets", "devil's weed", "hell's bells", "moonflowers", "thorn-apple" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Deschloroetizolam", "name": "Deschloroetizolam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 4 mg" }, { "name": "Common", "value": "4 - 6 mg" }, { "name": "Strong", "value": "6 - 12 mg" }, { "name": "Heavy", "value": "12 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 10 hours" }, { "name": "Onset", "value": "1 - 5 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "3 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Thienodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepine", "thienodiazepine" ] } }, { "url": "https://psychonautwiki.org/wiki/Deschloroketamine", "name": "Deschloroketamine", "aliases": [ "DCK", "DXE", "O-PCM" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "30 - 90 minutes" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "3 - 24 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "5 - 15 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "3 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/Desomorphine", "name": "Desomorphine", "aliases": [ "Krok", "Krokodil" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 10 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 20 mg" }, { "name": "Strong", "value": "20 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Desoxypipradrol", "name": "Desoxypipradrol", "aliases": [ "2-DPMP", "Desoxypipradol", "Ivory Wave" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.25 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 6 mg" }, { "name": "Strong", "value": "6 - 8 mg" }, { "name": "Heavy", "value": "8 mg +", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "16 - 72 hours" }, { "name": "Onset", "value": "1 - 4 hours" }, { "name": "Peak", "value": "9 - 30 hours" }, { "name": "Offset", "value": "6 - 40 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "0.25 mg" }, { "name": "Light", "value": "0.5 - 1.5 mg" }, { "name": "Common", "value": "1.5 - 3.5 mg" }, { "name": "Strong", "value": "3.5 - 5 mg" }, { "name": "Heavy", "value": "5 mg +", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "10 - 72 hours" }, { "name": "Onset", "value": "15 - 240 minutes" }, { "name": "Come up", "value": "2 - 6 hours" }, { "name": "Peak", "value": "6 - 30 hours" }, { "name": "Offset", "value": "6 - 40 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_piperidines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Dextromethorphan", "name": "Dextromethorphan", "aliases": [ "DM", "DMO", "DXM", "Delsym", "Dex", "DexAlone", "Duract", "Robitussin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "75 mg" }, { "name": "Light", "value": "100 - 200 mg" }, { "name": "Common", "value": "200 - 400 mg" }, { "name": "Strong", "value": "400 - 700 mg" }, { "name": "Heavy", "value": "700 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "30 - 120 minutes" }, { "name": "Come up", "value": "60 - 120 minutes" }, { "name": "Peak", "value": "3 - 6 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "4 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "produces dependence with chronic use and has moderate abuse potential", "crossTolerances": [ "dissociatives" ] } }, { "url": "https://psychonautwiki.org/wiki/Dextropropoxyphene", "name": "Dextropropoxyphene", "aliases": [ "Darvon", "propoxyphene" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "30 - 65 mg" }, { "name": "Common", "value": "65 - 100 mg" }, { "name": "Strong", "value": "100 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Onset", "value": "20 - 30 minutes" }, { "name": "Peak", "value": "1 - 4 hours" }, { "name": "After effects", "value": "1 - 6 hours" } ], "bioavailability": "40%" } ], "data": { "class": { "chemical": [ "Phenylpropylamine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "high toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines", "known to cause potentially fatal heart arrhythmias" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/DiPT", "name": "DiPT", "aliases": [], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 20 mg" }, { "name": "Strong", "value": "20 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "15 - 60 minutes" }, { "name": "Onset", "value": "5 - 15 minutes" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "15 - 30 mg" }, { "name": "Common", "value": "30 - 75 mg" }, { "name": "Strong", "value": "75 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Diazepam", "name": "Diazepam", "aliases": [ "Apaurin", "Diastat", "Mother's Little Helper", "Valium" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2.5 - 5 mg" }, { "name": "Common", "value": "5 - 15 mg" }, { "name": "Strong", "value": "15 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "After effects", "value": "12 - 36 hours" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7-14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Dichloropane", "name": "Dichloropane", "aliases": [ "RTI-111" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "2.5 mg" }, { "name": "Light", "value": "2.5 - 7.5 mg" }, { "name": "Common", "value": "7.5 - 20 mg" }, { "name": "Strong", "value": "20 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "40 - 75 minutes" }, { "name": "Onset", "value": "15 - 60 seconds" }, { "name": "Come up", "value": "15 - 60 seconds" }, { "name": "Peak", "value": "15 - 30 minutes" }, { "name": "Offset", "value": "20 - 40 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "60 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_tropanes" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "2 - 4 days", "zero": "1 - 1.5 weeks" }, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Diclazepam", "name": "Diclazepam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "0.5 - 1 mg" }, { "name": "Common", "value": "1 - 3 mg" }, { "name": "Strong", "value": "3 - 4 mg" }, { "name": "Heavy", "value": "4 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "10 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within 3-4 days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "GABAergic" ] } }, { "url": "https://psychonautwiki.org/wiki/Dihydrocodeine", "name": "Dihydrocodeine", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 150 mg" }, { "name": "Strong", "value": "150 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 4 hours" }, { "name": "Onset", "value": "30 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Diphenhydramine", "name": "Diphenhydramine", "aliases": [ "Benadryl", "DPH", "Nytol", "Sominex", "Unisom SleepMelts", "ZzzQuil" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "100 - 200 mg" }, { "name": "Common", "value": "200 - 400 mg" }, { "name": "Strong", "value": "400 - 700 mg" }, { "name": "Heavy", "value": "700 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 10 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "1 - 4 hours" }, { "name": "Offset", "value": "2 - 6 hours" }, { "name": "After effects", "value": "up to 24 hours" } ], "bioavailability": "40-60%" } ], "data": { "class": { "chemical": [ "Ethanolamine" ], "psychoactive": [ "Deliriant", "Depressant" ] }, "tolerance": { "full": "with repeated use", "half": null, "zero": "1 - 2 weeks" }, "toxicity": [ "fatal at amounts close to or exceeding 2 grams" ], "addictionPotential": "produces dependence with chronic use", "crossTolerances": [ "deliriant" ] } }, { "url": "https://psychonautwiki.org/wiki/Diphenidine", "name": "Diphenidine", "aliases": [], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "?? mg", "note": "\"??\" is not a number." }, { "name": "Light", "value": "?? - 20 mg", "note": "\"??\" is not a number." }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 55 mg" }, { "name": "Heavy", "value": "> 55 mg" } ], "duration": [ { "name": "Total", "value": "1 - 3 hours" }, { "name": "Onset", "value": "30 - 90 seconds" }, { "name": "Peak", "value": "0.5 - 2 hours" }, { "name": "Offset", "value": "20 - 40 minutes" }, { "name": "After effects", "value": "2 - 5 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "30 mg" }, { "name": "Light", "value": "40 - 65 mg" }, { "name": "Common", "value": "65 - 100 mg" }, { "name": "Strong", "value": "100 - 130 mg" }, { "name": "Heavy", "value": "> 130 mg" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "4 - 24 Hours" } ] }, { "name": "Rectal", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 80 mg" }, { "name": "Heavy", "value": "80 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 7 hours" }, { "name": "Onset", "value": "10 - 30 minutes" } ] } ], "data": { "class": { "chemical": [ "Diarylethylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/EPT", "name": "EPT", "aliases": [], "roas": [ { "name": "Insufflated", "dosage": [ { "name": "Light", "value": "20 - 40 mg" }, { "name": "Common", "value": "40 - 80 mg" }, { "name": "Strong", "value": "80 - 110 mg" }, { "name": "Heavy", "value": "110 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "5 - 20 minutes" }, { "name": "After effects", "value": "1 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "does not produce dependence and has low abuse potential", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/ETH-CAT", "name": "ETH-CAT", "aliases": [ "Ethcathinone", "Ethylpropion" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "60 mg" }, { "name": "Light", "value": "100 - 150 mg" }, { "name": "Common", "value": "150 - 225 mg" }, { "name": "Strong", "value": "225 - 325 mg" }, { "name": "Heavy", "value": "325 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "15 - 40 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "60 - 120 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "15 - 35 mg" }, { "name": "Common", "value": "35 - 70 mg" }, { "name": "Strong", "value": "70 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 3 hours" }, { "name": "Onset", "value": "1 - 5 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "30 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "2 - 3 days", "zero": "3-5 days" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "mildly addictive with a comparatively low potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/ETH-LAD", "name": "ETH-LAD", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 \u00b5g" }, { "name": "Light", "value": "30 - 60 \u00b5g" }, { "name": "Common", "value": "60 - 150 \u00b5g" }, { "name": "Strong", "value": "150 - 225 \u00b5g" }, { "name": "Heavy", "value": "225 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "8 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Efavirenz", "name": "Efavirenz", "aliases": [ "Sustiva" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Common", "value": "600 - 1800 mg" } ], "duration": [ { "name": "Onset", "value": "1 - 5 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "After effects", "value": "6 - 12 hours" } ], "bioavailability": "50%" } ], "data": { "class": { "chemical": [ "Benzoxazine" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": [ "low toxicity", "may cause liver toxicity at high doses or after chronic use" ], "addictionPotential": "not known to be habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Ephenidine", "name": "Ephenidine", "aliases": [ "NEDPA" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "30 mg" }, { "name": "Light", "value": "30 - 70 mg" }, { "name": "Common", "value": "70 - 100 mg" }, { "name": "Strong", "value": "100 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 7 hours" }, { "name": "Onset", "value": "10 - 30 minutes" } ] } ], "data": { "class": { "chemical": [ "Diarylethylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/Ephylone", "name": "Ephylone", "aliases": [ "bk-EBDP", "bk-ethyl-K", "\u03b2k-EBDP" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 80 mg" }, { "name": "Heavy", "value": null, "note": "Ephylone may be fatal at heavy doses." } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": null, "zero": null }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Escaline", "name": "Escaline", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "30 - 50 mg" }, { "name": "Common", "value": "50 - 100 mg" }, { "name": "Strong", "value": "100 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "90 - 120 minutes" }, { "name": "After effects", "value": "3 - 5 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Ethylmorphine", "name": "Ethylmorphine", "aliases": [ "codethyline", "dionine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 50 mg" }, { "name": "Common", "value": "50 - 100 mg" }, { "name": "Strong", "value": "100 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 5 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "2 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "very addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Ethylone", "name": "Ethylone", "aliases": [ "MDEC", "bk-MDEA" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "75 mg" }, { "name": "Light", "value": "75 - 150 mg" }, { "name": "Common", "value": "150 - 225 mg" }, { "name": "Strong", "value": "225 - 325 mg" }, { "name": "Heavy", "value": "325 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "60 - 120 minutes" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": null, "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Ethylphenidate", "name": "Ethylphenidate", "aliases": [ "EPH" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "20 - 40 mg" }, { "name": "Common", "value": "40 - 80 mg" }, { "name": "Strong", "value": "80 - 120 mg" }, { "name": "Heavy", "value": "120 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 7 hours" }, { "name": "Onset", "value": "40 - 120 minutes" } ] }, { "name": "Rectal", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg+" } ], "duration": [ { "name": "Total", "value": "2 - 6 hours" }, { "name": "Onset", "value": "5 - 20 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenidates" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopaminergic", "stimulants" ] } }, { "url": "https://psychonautwiki.org/wiki/Etizolam", "name": "Etizolam", "aliases": [ "Etilaam", "Etizest" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.2 mg" }, { "name": "Light", "value": "0.5 - 1 mg" }, { "name": "Common", "value": "1 - 2 mg" }, { "name": "Strong", "value": "2 - 5 mg" }, { "name": "Heavy", "value": "5 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 7 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1.5 - 2.5 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ], "bioavailability": "93%" } ], "data": { "class": { "chemical": [ "Thienodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "highly addictive with a high potential for abuse", "crossTolerances": [ "benzodiazepine", "thienodiazepine" ] } }, { "url": "https://psychonautwiki.org/wiki/F-Phenibut", "name": "F-Phenibut", "aliases": [ "Fluorobut", "Fluorophenibut" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "100 - 150 mg" }, { "name": "Common", "value": "150 - 400 mg" }, { "name": "Strong", "value": "400 - 600 mg" }, { "name": "Heavy", "value": "600 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 8 hours" }, { "name": "Onset", "value": "20 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Gabapentinoids" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids", "exact toxic dosage is unknown" ], "addictionPotential": "moderately physically and psychologically addictive", "crossTolerances": [ "GABA" ] } }, { "url": "https://psychonautwiki.org/wiki/Fentanyl", "name": "Fentanyl", "aliases": [ "Abstral", "Actiq", "Duragesic", "Durogesic", "Fentora", "Haldid", "Instanyl", "Lazanda", "Matrifen", "Onsolis", "Sublimaze", "fentanil" ], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "5 - 10 \u03bcg" }, { "name": "Light", "value": "10 - 25 \u03bcg" }, { "name": "Common", "value": "25 - 50 \u03bcg" }, { "name": "Strong", "value": "50 - 75 \u03bcg" }, { "name": "Heavy", "value": "75 \u03bcg +" } ], "duration": [ { "name": "Total", "value": "1 - 4 hours" }, { "name": "Onset", "value": "15 - 30 minutes" } ], "bioavailability": "50%" }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 - 10 \u03bcg" }, { "name": "Light", "value": "10 - 25 \u03bcg" }, { "name": "Common", "value": "25 - 50 \u03bcg" }, { "name": "Strong", "value": "50 - 75 \u03bcg" }, { "name": "Heavy", "value": "75 \u03bcg +" } ], "duration": [ { "name": "Total", "value": "1 - 4 hours" }, { "name": "Onset", "value": "15 - 30 minutes" } ], "bioavailability": "89%" }, { "name": "Transdermal", "dosage": [ { "name": "Threshold", "value": "5 - 12 \u03bcg" }, { "name": "Light", "value": "12 - 25 \u03bcg" }, { "name": "Common", "value": "25 - 50 \u03bcg" }, { "name": "Strong", "value": "50 - 100 \u03bcg" }, { "name": "Heavy", "value": "100 \u03bcg +" } ], "duration": [ { "name": "Total", "value": "48 - 72 hours" }, { "name": "Onset", "value": "2 - 4 hours" } ], "bioavailability": "92%" } ], "data": { "class": { "chemical": [ "Substituted_piperidines", "Anilidopiperidine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages", "potentially lethal when mixed with depressants like alcohol or benzodiazepines", "unintentionally transporting the substance from the skin by touching the mouth, nose or eyes is dangerous" ], "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Flubromazepam", "name": "Flubromazepam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "3 - 5 mg" }, { "name": "Common", "value": "5 - 8 mg" }, { "name": "Strong", "value": "8 - 12 mg" }, { "name": "Heavy", "value": "12 - 16 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 12 hours" }, { "name": "Onset", "value": "40 - 90 minutes" }, { "name": "After effects", "value": "24 hours" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Flubromazolam", "name": "Flubromazolam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 \u03bcg" }, { "name": "Light", "value": "100 - 150 \u03bcg" }, { "name": "Common", "value": "150 - 250 \u03bcg" }, { "name": "Strong", "value": "250 - 400 \u03bcg" }, { "name": "Heavy", "value": "400 \u03bcg +" } ], "duration": [ { "name": "Total", "value": "12 - 18 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "After effects", "value": "24 hours +" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/GBL", "name": "GBL", "aliases": [ "gamma-Butyrolactone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.3 ml" }, { "name": "Light", "value": "0.3 - 0.9 ml" }, { "name": "Common", "value": "0.9 - 1.5 ml" }, { "name": "Strong", "value": "1.5 - 3 ml", "note": "Warning: Doses over 2 ml can induce heavy sleep." }, { "name": "Heavy", "value": "3+ ml" } ], "duration": [ { "name": "Total", "value": "1 - 2 hours" }, { "name": "Onset", "value": "3 - 10 minutes" }, { "name": "Come up", "value": "5 - 15 minutes" }, { "name": "Peak", "value": "30 - 45 minutes" }, { "name": "Offset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "1 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Tetrahydrofuran" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within several days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": null, "addictionPotential": "highly physically and moderately to highly psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/GHB", "name": "GHB", "aliases": [ "G", "Sodium oxybate", "Xyrem" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 g" }, { "name": "Light", "value": "0.5 - 1 g" }, { "name": "Common", "value": "1 - 2.5 g" }, { "name": "Strong", "value": "2.5 - 4 g" }, { "name": "Heavy", "value": "4 g +", "note": "Warning: Risk of death above 10 g" } ], "duration": [ { "name": "Total", "value": "1.5 - 2.5 hours" }, { "name": "Onset", "value": "5 - 30 minutes" }, { "name": "Come up", "value": "10 - 20 minutes" }, { "name": "Peak", "value": "45 - 90 minutes" }, { "name": "Offset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Butyric_acid" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within several days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "Doses above 10 grams are associated with a risk of death", "considered to be a safe and non-toxic substance when used responsibly or medically" ], "addictionPotential": "moderately to highly physically and moderately psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Gabapentin", "name": "Gabapentin", "aliases": [ "Gabarone", "Gralise", "Neurontin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "200 mg" }, { "name": "Light", "value": "200 - 600 mg" }, { "name": "Common", "value": "600 - 900 mg" }, { "name": "Strong", "value": "900 - 1200 mg" }, { "name": "Heavy", "value": "1200 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" } ], "bioavailability": "27% - 60%" } ], "data": { "class": { "chemical": [ "Gabapentinoids" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "with prolonged continuous usage", "half": null, "zero": "7-14 days" }, "toxicity": [ "low toxicity" ], "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Galantamine", "name": "Galantamine", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "4 - 8 mg" }, { "name": "Common", "value": "8 - 16 mg" }, { "name": "Strong", "value": "16 - 24 mg" }, { "name": "Heavy", "value": "24 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 12 hours" }, { "name": "Onset", "value": "20 - 60 minutes" } ], "bioavailability": "90%" } ], "data": { "class": { "chemical": [ "Benzazepine" ], "psychoactive": [ "Sedative", "Oneirogen" ] }, "tolerance": null, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [] } }, { "url": "https://psychonautwiki.org/wiki/Haloperidol", "name": "Haloperidol", "aliases": [ "Haldol" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.25 mg" }, { "name": "Light", "value": "0.25 - 1 mg" }, { "name": "Common", "value": "1 - 5 mg" }, { "name": "Strong", "value": "5 - 10 mg" }, { "name": "Heavy", "value": "10 mg +" } ], "duration": [ { "name": "Total", "value": "12 - 36 hours" }, { "name": "Onset", "value": "30 - 60 minutes" } ], "bioavailability": "60-70%" } ], "data": { "class": { "chemical": [ "Butyrophenone", "Substituted_piperidines" ], "psychoactive": [ "Antipsychotic" ] }, "tolerance": null, "toxicity": [ "can have serious side effects at higher dosages", "risk of having severe extrapyramidal symptoms and muscle rigidity" ], "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Heroin", "name": "Heroin", "aliases": [ "Brown", "H", "Junk", "Smack" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "5 - 10 seconds" }, { "name": "Come up", "value": "5 - 10 seconds" }, { "name": "Peak", "value": "15 - 30 minutes" }, { "name": "Offset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "10 - 30 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "7.5 - 20 mg" }, { "name": "Common", "value": "20 - 35 mg" }, { "name": "Strong", "value": "35 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 7 hours" }, { "name": "Onset", "value": "10 - 60 seconds" }, { "name": "Come up", "value": "10 - 60 seconds" }, { "name": "Peak", "value": "1 - 90 minutes" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "1.5 - 3 hours" } ] }, { "name": "Intravenous", "dosage": [ { "name": "Common", "value": "5 - 8 mg" }, { "name": "Strong", "value": "8 - 15 mg" }, { "name": "Heavy", "value": "15 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 5 hours" }, { "name": "Onset", "value": "0 - 5 seconds" }, { "name": "Come up", "value": "-" }, { "name": "Peak", "value": "1 - 4 hours" }, { "name": "Offset", "value": "-" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Hexedrone", "name": "Hexedrone", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "30 mg" }, { "name": "Light", "value": "50 - 70 mg" }, { "name": "Common", "value": "70 - 100 mg" }, { "name": "Strong", "value": "100 - 125 mg" }, { "name": "Heavy", "value": "125 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 4 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "1 - 12 hours" } ] } ], "data": { "class": { "chemical": null, "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Hydrocodone", "name": "Hydrocodone", "aliases": [ "Vicodin (with paracetamol)", "Zohydro ER (extended-release)" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "10 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "with prolonged use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "potentially fatal at heavy dosages" ], "addictionPotential": "moderately addictive", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Hydromorphone", "name": "Hydromorphone", "aliases": [ "Dilaudid", "Jurnista", "Palladone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 4 mg" }, { "name": "Strong", "value": "4 - 8 mg" }, { "name": "Heavy", "value": "8 mg +" } ], "duration": [ { "name": "Onset", "value": "20 - 45 minutes" }, { "name": "Peak", "value": "3 - 4 hours" } ] }, { "name": "Intravenous", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 4 mg" }, { "name": "Strong", "value": "4 - 6 mg" }, { "name": "Heavy", "value": "6 mg +" } ], "duration": [ { "name": "Onset", "value": "10 - 90 seconds" }, { "name": "Peak", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Hyoscyamus_niger_(botany)", "name": "Hyoscyamus niger (botany)", "aliases": [ "Henbane", "Stinking nightshade" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Ibogaine", "name": "Ibogaine", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Common", "value": "15 - 22 mg/kg of body weight" }, { "name": "Strong", "value": null, "note": "Strong doses may result in fatal heart complications." } ], "duration": [ { "name": "Onset", "value": "30 - 180 minutes" }, { "name": "Peak", "value": "18 - 36 hours" }, { "name": "After effects", "value": "24 - 72 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": null, "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Isopropylphenidate", "name": "Isopropylphenidate", "aliases": [ "IPH", "IPPH" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 45 mg" }, { "name": "Heavy", "value": "45 mg +" } ], "duration": [ { "name": "Total", "value": "3.5 - 6 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 35 mg" }, { "name": "Heavy", "value": "35 mg +" } ], "duration": [ { "name": "Total", "value": "2.5 - 4 hours" }, { "name": "Onset", "value": "2 - 5 minutes" }, { "name": "Come up", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenidates" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/JWH-073", "name": "JWH-073", "aliases": [ "Spice" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "< 3 mg" }, { "name": "Light", "value": "3 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 15 mg" }, { "name": "Heavy", "value": "15 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "60 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Naphthoylindole" ], "psychoactive": [ "Cannabinoid" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "cannabinoids" ] } }, { "url": "https://psychonautwiki.org/wiki/Ketamine", "name": "Ketamine", "aliases": [ "Cat Tranquilizer", "K", "Ket", "Ketalar", "Ketanest", "Ketaset", "Kitty", "Special K" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 300 mg" }, { "name": "Strong", "value": "300 - 450 mg" }, { "name": "Heavy", "value": "450 mg+" } ], "duration": [ { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Come up", "value": "5 - 20 minutes" }, { "name": "Peak", "value": "45 - 90 minutes" }, { "name": "Offset", "value": "3 - 6 hours" }, { "name": "After effects", "value": "4 - 8 hours" } ], "bioavailability": "17%" }, { "name": "Sublingual", "dosage": null, "duration": null, "bioavailability": "20% - 29%" }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 30 mg" }, { "name": "Common", "value": "30 - 75 mg" }, { "name": "Strong", "value": "75 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 1.5 hours" }, { "name": "Onset", "value": "2 - 5 minutes" }, { "name": "Come up", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "30 - 60 minutes" }, { "name": "Offset", "value": "3 - 6 hours" }, { "name": "After effects", "value": "2 - 12 hours" } ], "bioavailability": "45%" } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderate to high abuse potential and produces psychological dependence with chronic use", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/Kratom", "name": "Kratom", "aliases": [ "Mitragyna speciosa", "ketum", "kratom or kratum", "\u0e01\u0e23\u0e30\u0e17\u0e48\u0e2d\u0e21 (Thai)" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 g" }, { "name": "Light", "value": "2 - 3 g" }, { "name": "Common", "value": "3 - 5 g" }, { "name": "Strong", "value": "5 - 8 g" }, { "name": "Heavy", "value": "8 g +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "3 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Indole_alkaloids" ], "psychoactive": [ "Stimulants", "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity" ], "addictionPotential": "produces dependence with chronic use and has a high abuse potential", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/LSA", "name": "LSA", "aliases": [ "Ergine" ], "roas": [], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": null, "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "non-addictive with a low abuse potential", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/LSD", "name": "LSD", "aliases": [ "Acid", "Blotter", "Cid", "L", "LSD-25", "Lucy", "Tabs" ], "roas": [ { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "15 \u00b5g" }, { "name": "Light", "value": "25 - 75 \u00b5g" }, { "name": "Common", "value": "75 - 150 \u00b5g" }, { "name": "Strong", "value": "150 - 300 \u00b5g" }, { "name": "Heavy", "value": "300 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "3 - 5 hours" }, { "name": "After effects", "value": "12 - 48 hours" } ], "bioavailability": "71% - 71%" } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": null, "zero": "7 days" }, "toxicity": [ "extremely low toxicity relative to dose" ], "addictionPotential": "non-addictive with a low abuse potential", "crossTolerances": [ "psychedelics" ] } }, { "url": "https://psychonautwiki.org/wiki/LSM-775", "name": "LSM-775", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "250 \u00b5g" }, { "name": "Light", "value": "500 - 750 \u00b5g" }, { "name": "Common", "value": "750 - 1250 \u00b5g" }, { "name": "Strong", "value": "1250 - 1500 \u00b5g" }, { "name": "Heavy", "value": "1500 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "10 - 30 minutes" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelics" ] } }, { "url": "https://psychonautwiki.org/wiki/LSZ", "name": "LSZ", "aliases": [ "Diazedine", "LA-SS-Az", "Lambda" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "100 - 150 \u00b5g" }, { "name": "Common", "value": "150 - 300 \u00b5g" }, { "name": "Strong", "value": "300 - 400 \u00b5g" }, { "name": "Heavy", "value": "400 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Lisdexamfetamine", "name": "Lisdexamfetamine", "aliases": [ "Elvanse", "Vyvanse" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "20 - 30 mg" }, { "name": "Common", "value": "30 - 60 mg" }, { "name": "Strong", "value": "60 - 90 mg" }, { "name": "Heavy", "value": "90 mg +" } ], "duration": [ { "name": "Total", "value": "10 - 14 hours" }, { "name": "Onset", "value": "60 - 90 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "4 - 6 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Lorazepam", "name": "Lorazepam", "aliases": [ "Ativan", "Lorsilan", "Orfidal" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.10 mg" }, { "name": "Light", "value": "0.25 - 0.5 mg" }, { "name": "Common", "value": "0.5 - 1.5 mg" }, { "name": "Strong", "value": "1.5 - 2 mg" }, { "name": "Heavy", "value": "2 - 3 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "5 - 30 minutes" }, { "name": "Peak", "value": "2 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/MCPP", "name": "MCPP", "aliases": [ "mCPP" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "20 - 50 mg" }, { "name": "Common", "value": "50 - 120 mg" }, { "name": "Strong", "value": "120 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "3 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_piperazines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/MDA", "name": "MDA", "aliases": [ "Sally", "Sass", "Tenamfetamine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "40 - 60 mg" }, { "name": "Common", "value": "60 - 100 mg" }, { "name": "Strong", "value": "100 - 145 mg" }, { "name": "Heavy", "value": "145 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "15 - 45 minutes" }, { "name": "Peak", "value": "2.5 - 4 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine" ], "psychoactive": [ "Stimulants", "Psychedelics", "Entactogens" ] }, "tolerance": { "full": "repeated and heavy usage", "half": "3 days", "zero": "7 days" }, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "psychedelic", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/MDAI", "name": "MDAI", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "40 mg" }, { "name": "Light", "value": "40 - 100 mg" }, { "name": "Common", "value": "100 - 175 mg" }, { "name": "Strong", "value": "175 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 2.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Aminoindane" ], "psychoactive": [ "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "somewhat habit-forming with a low potential for abuse", "crossTolerances": [ "entactogens" ] } }, { "url": "https://psychonautwiki.org/wiki/MDEA", "name": "MDEA", "aliases": [ "Eve", "MDE" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "40 mg" }, { "name": "Light", "value": "70 - 120 mg" }, { "name": "Common", "value": "120 - 180 mg" }, { "name": "Strong", "value": "180 - 225 mg" }, { "name": "Heavy", "value": "225 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "1.5 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "12 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "MDxx", "Substituted_amphetamines" ], "psychoactive": [ "Entactogens" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "1-1.5 months", "zero": "2-3 months" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "serotonin|serotonergic", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/MDMA", "name": "MDMA", "aliases": [ "Beans", "E", "Ecstasy", "Emma", "MD", "Mandy", "Molly", "Rolls", "X", "XTC" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "15 - 55 mg" }, { "name": "Common", "value": "55 - 125 mg" }, { "name": "Strong", "value": "125 - 180 mg" }, { "name": "Heavy", "value": "180 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" }, { "name": "After effects", "value": "12 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "MDxx", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "1 month", "zero": "2.5 months" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopaminergic", "serotonergic", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/MDPV", "name": "MDPV", "aliases": [ "Bath Salts", "NRG-1" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "4 - 8 mg" }, { "name": "Common", "value": "8 - 14 mg" }, { "name": "Strong", "value": "14 - 25 mg" }, { "name": "Heavy", "value": "25 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 7 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "1 - 4 hours" }, { "name": "Offset", "value": "0.5 - 2 hours" }, { "name": "After effects", "value": "2 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "MDxx", "Pyrrolidinophenone", "Substituted_cathinones" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/MET", "name": "MET", "aliases": [ "Methylethyltryptamine" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "20 - 40 mg" }, { "name": "Common", "value": "40 - 60 mg" }, { "name": "Strong", "value": "60 - 90 mg" }, { "name": "Heavy", "value": "90 mg +" } ], "duration": [ { "name": "Total", "value": "30 - 75 minutes" }, { "name": "Onset", "value": "30 - 60 seconds" }, { "name": "Peak", "value": "10 - 20 minutes" }, { "name": "Offset", "value": "20 - 40 minutes" }, { "name": "After effects", "value": "20 - 60 minutes" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "40 mg" }, { "name": "Light", "value": "60 - 120 mg" }, { "name": "Common", "value": "120 - 150 mg" }, { "name": "Strong", "value": "150 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "1 - 2 hours" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 25 mg" }, { "name": "Strong", "value": "25 - 35 mg" }, { "name": "Heavy", "value": "35 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "2 - 5 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1 - 1.5 hours" }, { "name": "Offset", "value": "1 - 2.5 hours" }, { "name": "After effects", "value": "4 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": null, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/MPT", "name": "MPT", "aliases": [ "Methylpropyltryptamine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Common", "value": "??? -\u00a0??? mg", "note": "\"???\" is not a number." } ], "duration": [ { "name": "Total", "value": "??? -\u00a0???" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/MXiPr", "name": "MXiPr", "aliases": [ "MXiP", "MXiPR" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "1.5 - 4 hours" }, { "name": "Onset", "value": "2 - 5 minutes" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/Mandragora", "name": "Mandragora", "aliases": [ "Mandrake" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Mandragora_officinarum_(botany)", "name": "Mandragora officinarum (botany)", "aliases": [ "Mandrake" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Melatonin", "name": "Melatonin", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.25 mg" }, { "name": "Light", "value": "0.5 - 1 mg" }, { "name": "Common", "value": "1 - 3 mg" }, { "name": "Strong", "value": "3 - 6 mg" }, { "name": "Heavy", "value": "6 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "5 - 20 minutes" } ], "bioavailability": "15% - 15%" } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Oneirogen" ] }, "tolerance": { "full": "after prolonged and repeated usage", "half": "7 days", "zero": "14 days" }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [] } }, { "url": "https://psychonautwiki.org/wiki/Memantine", "name": "Memantine", "aliases": [ "Ebixa", "Memaxa", "Namenda", "Namenda XR", "Namzaric (with donepezil", "both extended-release)" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "30 - 70 mg" }, { "name": "Common", "value": "70 - 110 mg" }, { "name": "Strong", "value": "110 - 170 mg" }, { "name": "Heavy", "value": "170 mg +" } ], "duration": [ { "name": "Total", "value": "~ 24 - 72 hours" }, { "name": "Onset", "value": "2 - 3 hours" }, { "name": "Come up", "value": "2 - 3 hours" }, { "name": "Peak", "value": "3 - 12 hours" }, { "name": "Offset", "value": "5 - 24 hours" }, { "name": "After effects", "value": "24 - 48 hours" } ], "bioavailability": "41 - 63%" } ], "data": { "class": { "chemical": [ "Adamantanes" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": null, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "unknown", "crossTolerances": [ "dissociatives" ] } }, { "url": "https://psychonautwiki.org/wiki/Mephedrone", "name": "Mephedrone", "aliases": [ "4-MMC", "Drone", "M-CAT", "Meow Meow" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "15 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 200 mg" }, { "name": "Strong", "value": "200 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "30 - 90 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "15 - 45 mg" }, { "name": "Common", "value": "45 - 80 mg" }, { "name": "Strong", "value": "80 - 125 mg" }, { "name": "Heavy", "value": "125 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "30 - 60 minutes" }, { "name": "Offset", "value": "30 - 90 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Mescaline", "name": "Mescaline", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "100 - 200 mg" }, { "name": "Common", "value": "200 - 400 mg" }, { "name": "Strong", "value": "400 - 800 mg" }, { "name": "Heavy", "value": "800 mg+" } ], "duration": [ { "name": "Total", "value": "8 - 14 hours" }, { "name": "Onset", "value": "45 - 90 minutes" }, { "name": "Come up", "value": "60 - 120 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "6 - 36 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Methadone", "name": "Methadone", "aliases": [ "Dolophine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "3 - 5 mg" }, { "name": "Common", "value": "5 - 15 mg" }, { "name": "Strong", "value": "15 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Onset", "value": "20 - 90 minutes" }, { "name": "Peak", "value": "6 - 8 hours" }, { "name": "After effects", "value": "1 - 24 hours" } ], "bioavailability": "40-99%" } ], "data": { "class": { "chemical": [ "Diphenylpropylamine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "moderate toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Methallylescaline", "name": "Methallylescaline", "aliases": [ "MAL" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "15 - 25 mg" }, { "name": "Common", "value": "25 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 12 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "4 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Methamphetamine", "name": "Methamphetamine", "aliases": [ "Crank", "Glass", "Ice", "Meth", "Shard", "Speed", "Tina" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 6 hours", "note": "Up to 12h for irregular users." }, { "name": "Onset", "value": "7 - 10 seconds" }, { "name": "Come up", "value": "5 - 10 seconds" }, { "name": "Peak", "value": "1 - 3 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "2 - 24 hours" } ], "bioavailability": ">90%" }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 60 mg" }, { "name": "Heavy", "value": "60 - 150 mg +" } ], "duration": [ { "name": "Total", "value": "7 - 12 hours", "note": "Up to 24h for irregular users." }, { "name": "Onset", "value": "20 - 45 minutes" }, { "name": "Come up", "value": "2.6 - 3.6 hours" }, { "name": "Peak", "value": "3 - 5 hours" }, { "name": "Offset", "value": "3 - 4 hours" }, { "name": "After effects", "value": "12 - 24 hours" } ], "bioavailability": "~70%" }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 30 mg" }, { "name": "Strong", "value": "30 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 7", "note": "Up to 12h for irregular users." }, { "name": "Onset", "value": "3 - 5" }, { "name": "Come up", "value": "3 - 5" }, { "name": "Peak", "value": "1.5 - 3 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ], "bioavailability": ">90%" }, { "name": "Rectal", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 30 mg" }, { "name": "Strong", "value": "30 - 40 mg" }, { "name": "Heavy", "value": "40 mg+" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours", "note": "Up to 18h for irregular users." }, { "name": "Onset", "value": "5 - 15 minutes" }, { "name": "Come up", "value": "-" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "-" }, { "name": "After effects", "value": "-" } ], "bioavailability": "~99%" }, { "name": "Intravenous", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 30 mg" }, { "name": "Strong", "value": "30 - 40 mg" }, { "name": "Heavy", "value": "40 - 80 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours", "note": "Up to 18h for irregular users." }, { "name": "Onset", "value": "15 - 30 seconds" }, { "name": "Come up", "value": "-" }, { "name": "Peak", "value": "1 - 3 hours" }, { "name": "Offset", "value": "-" }, { "name": "After effects", "value": "-" } ], "bioavailability": "~100%" } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "rapidly develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulants" ] } }, { "url": "https://psychonautwiki.org/wiki/Methaqualone", "name": "Methaqualone", "aliases": [ "Ludes", "Mandrax", "Quaaludes", "Sopor" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 200 mg" }, { "name": "Strong", "value": "200 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "75 - 150 mg" }, { "name": "Light", "value": "150 - 300 mg" }, { "name": "Common", "value": "300 - 500 mg" }, { "name": "Strong", "value": "500 - 600 mg" }, { "name": "Heavy", "value": "600 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "30 minutes" }, { "name": "Come up", "value": "30 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "6 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Quinazolinone" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of repeated administration", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "doses of over 300mg can be dangerous for first time users", "safe at appropriate dosages" ], "addictionPotential": "extremely addictive", "crossTolerances": [ "GABA|gabaergic", "depressants" ] } }, { "url": "https://psychonautwiki.org/wiki/Methiopropamine", "name": "Methiopropamine", "aliases": [ "MPA" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "20 - 30 mg" }, { "name": "Common", "value": "30 - 50 mg" }, { "name": "Strong", "value": "50 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 4 hours" }, { "name": "Offset", "value": "2 - 3 hours" }, { "name": "After effects", "value": "1 - 2 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Come up", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "30 - 60 minutes" }, { "name": "Offset", "value": "30 - 120 minutes" }, { "name": "After effects", "value": "6 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Thiophene" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Methoxetamine", "name": "Methoxetamine", "aliases": [ "MXE", "Mexxy" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 45 mg" }, { "name": "Strong", "value": "45 - 70 mg" }, { "name": "Heavy", "value": "70 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" }, { "name": "After effects", "value": "6 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 35 mg" }, { "name": "Strong", "value": "35 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "5 - 20 minutes" }, { "name": "Come up", "value": "30 - 75 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 1.5 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/Methoxphenidine", "name": "Methoxphenidine", "aliases": [ "2-MXP", "MXP", "Methoxyphenidine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "30 mg" }, { "name": "Light", "value": "50 - 75 mg" }, { "name": "Common", "value": "75 - 120 mg" }, { "name": "Strong", "value": "120 - 150 mg" } ], "duration": [ { "name": "Total", "value": "6 - 8 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "After effects", "value": "1 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Diarylethylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/Methylnaphthidate", "name": "Methylnaphthidate", "aliases": [ "HDMP-28" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "4 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "1 - 10 minutes" }, { "name": "Peak", "value": "1.5 - 2 hours" }, { "name": "Offset", "value": "1.5 - 2 hours" }, { "name": "After effects", "value": "1 - 8 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "< 4 mg" }, { "name": "Light", "value": "4 - 8 mg" }, { "name": "Common", "value": "8 - 14 mg" }, { "name": "Strong", "value": "14 - 28 mg" }, { "name": "Heavy", "value": "28 mg +" } ], "duration": [ { "name": "Total", "value": "90 - 180 minutes" }, { "name": "Onset", "value": "3 - 6 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenidates" ], "psychoactive": [ "Stimulants" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Methylone", "name": "Methylone", "aliases": [ "M1", "MDMC", "bk-MDMA" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "75 mg" }, { "name": "Light", "value": "75 - 150 mg" }, { "name": "Common", "value": "150 - 225 mg" }, { "name": "Strong", "value": "225 - 325 mg" }, { "name": "Heavy", "value": "325 mg +" } ], "duration": [ { "name": "Total", "value": "2.5 - 4 hours" }, { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Come up", "value": "15 - 45 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "60 - 90 minutes" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants", "Entactogens" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "1 - 3 weeks", "zero": "3 - 6 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Methylphenidate", "name": "Methylphenidate", "aliases": [ "Concerta", "Equasym XL", "Methylin", "Ritalin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "1.5 - 2.5 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ], "bioavailability": "11-52%" }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "5 - 20 minutes" }, { "name": "Come up", "value": "15 - 40 minutes" }, { "name": "Peak", "value": "30 - 45 minutes" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "1 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenidates" ], "psychoactive": [ "Stimulants" ] }, "tolerance": null, "toxicity": null, "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Metizolam", "name": "Metizolam", "aliases": [ "Desmethyletizolam" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 1 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 4 mg" }, { "name": "Strong", "value": "4 - 6 mg" }, { "name": "Heavy", "value": "6 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "After effects", "value": "10 - 30 hours" } ] } ], "data": { "class": { "chemical": [ "Thienodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of repeated administration", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "large therapeutic index and margin of safety" ], "addictionPotential": "extremely addictive", "crossTolerances": [ "thienzodiazepines", "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Mexedrone", "name": "Mexedrone", "aliases": [ "4-MMC-MeO" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "100 - 150 mg" }, { "name": "Common", "value": "150 - 250 mg" }, { "name": "Strong", "value": "250 - 350 mg" }, { "name": "Heavy", "value": "350 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/MiPLA", "name": "MiPLA", "aliases": [ "Lamide" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "100 - 150 \u00b5g" }, { "name": "Common", "value": "150 - 200 \u00b5g" }, { "name": "Strong", "value": "200 - 250 \u00b5g" }, { "name": "Heavy", "value": "300 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Come up", "value": "45 - 90 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "low potential for abuse and dependence", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/MiPT", "name": "MiPT", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Common", "value": "10 - 25 mg" }, { "name": "Strong", "value": "25 - 75 mg" }, { "name": "Heavy", "value": "- mg" } ], "duration": [ { "name": "Total", "value": "3 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Mirtazapine", "name": "Mirtazapine", "aliases": [ "Avanza", "Axit", "Mirtaz", "Mirtazon", "Remeron", "Zispin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3.5 mg" }, { "name": "Light", "value": "70 - 130 mg" }, { "name": "Common", "value": "130 - 190 mg" }, { "name": "Strong", "value": "190 - 250 mg" }, { "name": "Heavy", "value": "250 mg +" } ], "duration": [ { "name": "Total", "value": "14 - 24 hours" }, { "name": "Onset", "value": "15 - 30 min" }, { "name": "Peak", "value": "90 - 180 min" }, { "name": "Offset", "value": "2 - 6 hours" }, { "name": "After effects", "value": "up to 24 hours" } ], "bioavailability": "50%" } ], "data": { "class": { "chemical": [ "Piperazinoazepine" ], "psychoactive": [ "Deliriant", "Antidepressant", "Depressant" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": null, "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Modafinil", "name": "Modafinil", "aliases": [ "Alertec", "Modalert", "Modavigil", "Modiodal", "Provigil" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 200 mg" }, { "name": "Strong", "value": "200 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 10 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "3.5 - 5 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Benzhydryl" ], "psychoactive": [ "Eugeroic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "The median lethal dose at which 50% of participants die (LD50) from modafinil for human beings has never been reached" ], "addictionPotential": "not addictive with a low potential for abuse", "crossTolerances": [ "benzhydryl", "nootropic|nootropics" ] } }, { "url": "https://psychonautwiki.org/wiki/Morphine", "name": "Morphine", "aliases": [ "MSContin", "Oramorph", "Sevredol", "Zomorph" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 10 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 20 mg" }, { "name": "Strong", "value": "20 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Myristicin", "name": "Myristicin", "aliases": [ "Nutmeg" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Light", "value": "50 - 200 mg" }, { "name": "Common", "value": "200 - 500 mg" }, { "name": "Strong", "value": "500 - 800 mg" }, { "name": "Heavy", "value": "800 mg +" } ], "duration": [ { "name": "Total", "value": "12 - 72 hours" }, { "name": "Onset", "value": "3 - 8 hours" }, { "name": "Come up", "value": "1 - 4 hours" }, { "name": "Peak", "value": "9 - 12 hours" }, { "name": "Offset", "value": "12 - 48 hours" }, { "name": "After effects", "value": "24 - 72 hours" } ] } ], "data": { "class": { "chemical": [ "Phenylpropenes" ], "psychoactive": [ "Deliriant" ] }, "tolerance": null, "toxicity": [ "is neurotoxic", "can be fatal in extremely high doses" ], "addictionPotential": "is not known to be addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/N-Acetylcysteine", "name": "N-Acetylcysteine", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "100 mg" }, { "name": "Light", "value": "400 - 600 mg" }, { "name": "Common", "value": "600 - 1000 mg" }, { "name": "Strong", "value": "1000 - 1500 mg" }, { "name": "Heavy", "value": "1500 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "20 - 60 minutes" } ], "bioavailability": "4%" } ], "data": { "class": { "chemical": [ "Substituted_amino_acid", "Cysteine" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "develops quickly with repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/N-Ethylhexedrone", "name": "N-Ethylhexedrone", "aliases": [ "Ethyl-Hexedrone", "Hex-en", "Hexen", "NEH" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 4 hours" }, { "name": "Onset", "value": "2 - 10 minutes" }, { "name": "Peak", "value": "10 - 30 minutes" }, { "name": "Offset", "value": "15 - 30 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "15 - 30 mg" }, { "name": "Common", "value": "30 - 40 mg" }, { "name": "Strong", "value": "40 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "2 - 8 minutes" }, { "name": "Peak", "value": "30 - 90 minutes" }, { "name": "Offset", "value": "1 - 4 hours" }, { "name": "After effects", "value": "1 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "norepinephrine|noradrenergic", "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/NEP", "name": "NEP", "aliases": [ "Ethyl-Pentedrone", "N-Ethylpentedrone" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "5 - 15 mg" }, { "name": "Common", "value": "15 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "1.5 - 3 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/NM-2-AI", "name": "NM-2-AI", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 150 mg" }, { "name": "Strong", "value": "150 - 200 mg" }, { "name": "Heavy", "value": "200 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "30 - 60 minutes" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Aminoindane" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Naloxone", "name": "Naloxone", "aliases": [ "Evzio", "Narcan" ], "roas": [ { "name": "Insufflated", "dosage": [ { "name": "Common", "value": "1 - 4 mg" } ], "duration": [ { "name": "Total", "value": "30 - 60 minutes" }, { "name": "Onset", "value": "0 - 10 minutes" } ] }, { "name": "Intramuscular", "dosage": [ { "name": "Common", "value": "0.4 - 2 mg" } ], "duration": [ { "name": "Total", "value": "30 - 60 minutes" }, { "name": "Onset", "value": "0.25 - 2 minutes" } ] }, { "name": "Intravenous", "dosage": [ { "name": "Common", "value": "0.4 - 2 mg" } ], "duration": [ { "name": "Total", "value": "30 - 60 minutes" }, { "name": "Onset", "value": "0.25 - 2 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": null, "toxicity": null, "addictionPotential": "not habit-forming", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Nicotine", "name": "Nicotine", "aliases": [], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "0.2 mg" }, { "name": "Light", "value": "0.3 - 0.8 mg" }, { "name": "Common", "value": "0.8 - 1.5 mg" }, { "name": "Strong", "value": "1.5 - 3.5 mg" }, { "name": "Heavy", "value": "3.5 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 3 hours" }, { "name": "Onset", "value": "5 - 20 seconds" }, { "name": "Come up", "value": "5 - 10 seconds" }, { "name": "Peak", "value": "2 - 5 minutes" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 3 hours" } ] }, { "name": "Buccal", "dosage": [ { "name": "Threshold", "value": "" }, { "name": "Light", "value": "- mg" }, { "name": "Common", "value": "- mg" }, { "name": "Strong", "value": "- mg" }, { "name": "Heavy", "value": "mg +" } ], "duration": [ { "name": "Total", "value": "-" }, { "name": "Onset", "value": "-" }, { "name": "Come up", "value": "-" }, { "name": "Peak", "value": "-" }, { "name": "Offset", "value": "-" }, { "name": "After effects", "value": "-" } ] } ], "data": { "class": { "chemical": [ "Pyridine", "Substituted_pyrrolidines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "rapidly develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Nifoxipam", "name": "Nifoxipam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.10 mg" }, { "name": "Light", "value": "0.25 - 0.5 mg" }, { "name": "Common", "value": "0.5 - 1 mg" }, { "name": "Strong", "value": "1 - 2 mg" }, { "name": "Heavy", "value": "2 mg +" } ], "duration": [ { "name": "Total", "value": "10 - 75 hours" }, { "name": "Onset", "value": "45 - 120 minutes" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/O-Desmethyltramadol", "name": "O-Desmethyltramadol", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 50 mg" }, { "name": "Strong", "value": "50 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "2 - 5 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "1 - 3 hours" } ] }, { "name": "Sublingual", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 50 mg" }, { "name": "Strong", "value": "50 - 80 mg" }, { "name": "Heavy", "value": "80 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 10 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "2 - 5 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "1 - 3 hours" } ] } ], "data": { "class": { "chemical": [ "Phenylpropylamine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "moderate potential toxicity relative to its dose due to its potency", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/O-PCE", "name": "O-PCE", "aliases": [ "Eticyclidone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "3 - 5 mg" }, { "name": "Common", "value": "5 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "3 - 6 mg" }, { "name": "Common", "value": "6 - 12 mg" }, { "name": "Strong", "value": "12 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "2 - 5 minutes" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/Omberacetam", "name": "Omberacetam", "aliases": [ "GVS-111", "Noopept", "\u041d\u043e\u043e\u043f\u0435\u043f\u0442" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "2 hours" }, { "name": "Offset", "value": "3 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "1 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 5 hours" }, { "name": "Onset", "value": "0 - 5 minutes" }, { "name": "Peak", "value": "2 hours" }, { "name": "Offset", "value": "3 hours" } ] } ], "data": { "class": { "chemical": [ "Peptide" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "develops over several weeks of prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "non-addictive with a low potential for abuse", "crossTolerances": [ "racetam", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Oxiracetam", "name": "Oxiracetam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "250 mg" }, { "name": "Light", "value": "500 - 1200 mg" }, { "name": "Common", "value": "1200 - 1800 mg" }, { "name": "Strong", "value": "1800 - 2400 mg" }, { "name": "Heavy", "value": "2400 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 10 hours" }, { "name": "Onset", "value": "30 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Racetams" ], "psychoactive": [ "Stimulants", "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "safe even when high doses are consumed for a long period of time", "exact toxic dosage is unknown" ], "addictionPotential": "non-addictive with a low potential for abuse", "crossTolerances": [ "racetam", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Oxycodone", "name": "Oxycodone", "aliases": [ "Codilek", "Endone", "Oxecta", "Oxy", "OxyContin", "OxyIR", "Oxydor", "Oxygesic", "Oxynor", "Redocam", "Roxicodone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2.5 - 10 mg" }, { "name": "Common", "value": "10 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 40 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2.5 - 7.5 mg" }, { "name": "Common", "value": "7.5 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 5 hours" }, { "name": "Onset", "value": "2 - 5 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Oxymorphone", "name": "Oxymorphone", "aliases": [ "Opana" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2.5 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 20 mg" }, { "name": "Strong", "value": "20 - 30 mg" }, { "name": "Heavy", "value": "30 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_morphinans" ], "psychoactive": [ "Opioids" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/PARGY-LAD", "name": "PARGY-LAD", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 \u00b5g" }, { "name": "Light", "value": "125 - 275 \u00b5g" }, { "name": "Common", "value": "275 - 500 \u00b5g" }, { "name": "Strong", "value": "500 - 700 \u00b5g" }, { "name": "Heavy", "value": "700 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "6 - 8 hours" }, { "name": "Onset", "value": "30 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/PCE", "name": "PCE", "aliases": [ "Eticyclidine" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 4 mg" }, { "name": "Common", "value": "4 - 8 mg" }, { "name": "Strong", "value": "8 - 12 mg" }, { "name": "Heavy", "value": "12 mg+", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "2 - 20 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "3 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 15 mg" }, { "name": "Heavy", "value": "15mg+", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "40 - 120 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 4 mg" }, { "name": "Common", "value": "4 - 8 mg" }, { "name": "Strong", "value": "8 - 15 mg" }, { "name": "Heavy", "value": "15mg+", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "3 - 30 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", "crossTolerances": [ "dissociative" ] } }, { "url": "https://psychonautwiki.org/wiki/PCP", "name": "PCP", "aliases": [ "Angel Dust", "Sernyl", "Sherman", "Wet" ], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 4 mg" }, { "name": "Common", "value": "4 - 8 mg" }, { "name": "Strong", "value": "8 - 12 mg" }, { "name": "Heavy", "value": "12 mg+", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "2 - 20 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "3 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 15 mg" }, { "name": "Heavy", "value": "15mg+", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "40 - 120 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 4 mg" }, { "name": "Common", "value": "4 - 8 mg" }, { "name": "Strong", "value": "8 - 15 mg" }, { "name": "Heavy", "value": "15mg+", "note": "Heavy doses may result in psychosis and mania." } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "3 - 30 minutes" }, { "name": "Come up", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "4 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Arylcyclohexylamines" ], "psychoactive": [ "Dissociatives" ] }, "tolerance": { "full": "with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", "crossTolerances": [ "dissociative|dissociatives" ] } }, { "url": "https://psychonautwiki.org/wiki/PMA", "name": "PMA", "aliases": [ "4-MA", "Death" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 10 mg" }, { "name": "Light", "value": "20 - 40 mg" }, { "name": "Common", "value": "40 - 60 mg" }, { "name": "Strong", "value": null, "note": "Higher dosages can result in serious hyperthermia and eventually death." } ], "duration": [ { "name": "Total", "value": "short" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Entactogens" ] }, "tolerance": null, "toxicity": [ "can be considered extremely toxic when compared to other substances such as Methamphetamine or MDMA", "Ingestion of PMA has been associated with severe tachycardia (abnormally high heart rate), seizures, hyperthermia, and death" ], "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/PMMA", "name": "PMMA", "aliases": [ "4-MMA", "PMA" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Common", "value": "100 - 120 mg" }, { "name": "Strong", "value": null, "note": "Higher dosages can result in serious hyperthermia and eventually death." } ], "duration": [ { "name": "Total", "value": "short" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Entactogens" ] }, "tolerance": null, "toxicity": [ "can be considered extremely toxic when compared to other substances such as Methamphetamine or MDMA", "Ingestion of PMMA has been associated with severe tachycardia (abnormally high heart rate), seizures, hyperthermia, and death" ], "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/PRO-LAD", "name": "PRO-LAD", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 \u00b5g" }, { "name": "Light", "value": "50 - 100 \u00b5g" }, { "name": "Common", "value": "100 - 200 \u00b5g" }, { "name": "Strong", "value": "200 - 350 \u00b5g" }, { "name": "Heavy", "value": "350 \u00b5g +" } ], "duration": [ { "name": "Total", "value": "6 - 8 hours" }, { "name": "Onset", "value": "30 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "Lysergamides" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "5-7 days", "zero": "14 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Peganum_harmala", "name": "Peganum harmala", "aliases": [ "Esfand", "Espand", "Syrian rue" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Pentedrone", "name": "Pentedrone", "aliases": [ "Drone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 15 mg" }, { "name": "Strong", "value": "15 - 25 mg" }, { "name": "Heavy", "value": "25 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 6 hours" }, { "name": "Onset", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 10 hours" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "2 - 5 mg" }, { "name": "Common", "value": "5 - 10 mg" }, { "name": "Strong", "value": "10 - 20 mg" }, { "name": "Heavy", "value": "20 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 4 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "30 - 90 minutes" }, { "name": "Offset", "value": "30 - 90 minutes" }, { "name": "After effects", "value": "1 - 8 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_cathinones" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Pentobarbital", "name": "Pentobarbital", "aliases": [ "Nembutal", "pentobarbitone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 200 mg" }, { "name": "Strong", "value": "200 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "15 - 60 minutes" }, { "name": "Peak", "value": "1 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "1 - 36 hours" } ] } ], "data": { "class": { "chemical": [ "Barbiturates" ], "psychoactive": [ "Depressant" ] }, "tolerance": null, "toxicity": [ "moderate toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Pethidine", "name": "Pethidine", "aliases": [ "Demerol", "Dolantin", "Dolcontral", "Meperidine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 - 50 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 200 mg" }, { "name": "Strong", "value": "200 - 400 mg" }, { "name": "Heavy", "value": "400 mg +" } ], "duration": [ { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "After effects", "value": "2 - 10 hours" } ], "bioavailability": "50-60%" } ], "data": { "class": { "chemical": [ "Substituted_piperidines" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "high toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Phenibut", "name": "Phenibut", "aliases": [ "Fenibut", "PhGABA", "Phenybut" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.25 g" }, { "name": "Light", "value": "0.5 - 1 g" }, { "name": "Common", "value": "1 - 2 g" }, { "name": "Strong", "value": "2 - 3.5 g" }, { "name": "Heavy", "value": "3.5 g +" } ], "duration": [ { "name": "Total", "value": "10 - 16 hours" }, { "name": "Onset", "value": "1.5 - 3 hours" }, { "name": "Come up", "value": "1.5 - 3 hours" }, { "name": "Peak", "value": "3 - 4 hours" }, { "name": "Offset", "value": "4 - 6 hours" }, { "name": "After effects", "value": "6 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Gabapentinoids" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids" ], "addictionPotential": "moderately physically and psychologically addictive", "crossTolerances": [ "GABA" ] } }, { "url": "https://psychonautwiki.org/wiki/Phenobarbital", "name": "Phenobarbital", "aliases": [ "Luminal", "phenobarb", "phenobarbitone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 150 mg" }, { "name": "Strong", "value": "150 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Onset", "value": "15 - 60 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "After effects", "value": "1 - 48 hours" } ] } ], "data": { "class": { "chemical": [ "Barbiturates" ], "psychoactive": [ "Depressant" ] }, "tolerance": null, "toxicity": [ "moderate toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Phenylpiracetam", "name": "Phenylpiracetam", "aliases": [ "Carphedon", "Phenotropil" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "< 50 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 200 mg" }, { "name": "Strong", "value": "200 - 400 mg" }, { "name": "Heavy", "value": "400 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 3 hours (some users have reported effects lasting an entire day)" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "1 hour" } ] } ], "data": { "class": { "chemical": [ "Racetams" ], "psychoactive": [ "Stimulants", "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "safe even when high doses are consumed for a long period of time", "exact toxic dosage is unknown" ], "addictionPotential": "non-addictive with a low potential for abuse", "crossTolerances": [ "racetam", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Piper_nigrum_(botany)", "name": "Piper nigrum (botany)", "aliases": [ "Black pepper", "Green pepper", "White pepper", "peppercorn" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Piracetam", "name": "Piracetam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.25 - 0.5g" }, { "name": "Light", "value": "0.5 - 2g" }, { "name": "Common", "value": "2 - 3g" }, { "name": "Strong", "value": "3 - 5g" }, { "name": "Heavy", "value": "5g +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "30 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Racetams" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "not addictive with a low potential for abuse", "crossTolerances": [ "racetam", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Pramiracetam", "name": "Pramiracetam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "100 mg" }, { "name": "Light", "value": "250 - 500 mg" }, { "name": "Common", "value": "500 - 800 mg" }, { "name": "Strong", "value": "800 - 1200 mg" }, { "name": "Heavy", "value": "1200 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 7 hours" }, { "name": "Onset", "value": "30 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Racetams" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "not addictive with a low potential for abuse", "crossTolerances": [ "racetam", "nootropic" ] } }, { "url": "https://psychonautwiki.org/wiki/Prochlorperazine", "name": "Prochlorperazine", "aliases": [ "Buccastem", "Compazine", "Phenotil", "Stemetil", "Stemzine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "2.5 - 5 mg" }, { "name": "Common", "value": "5 - 20 mg" }, { "name": "Strong", "value": "20 - 40 mg" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "30 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "Phenothiazine" ], "psychoactive": [ "Antipsychotic" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Prolintane", "name": "Prolintane", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "15 - 25 mg" }, { "name": "Common", "value": "25 - 45 mg" }, { "name": "Strong", "value": "45 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Come up", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_pyrrolidines", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Propylhexedrine", "name": "Propylhexedrine", "aliases": [ "Benzedrex" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "31.25 - 62.5 mg" }, { "name": "Common", "value": "62.5 - 125 mg" }, { "name": "Strong", "value": "125 - 187.5 mg" }, { "name": "Heavy", "value": "187.5 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 10 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Come up", "value": "15 - 90 minutes" }, { "name": "Peak", "value": "2 - 5 hours" }, { "name": "Offset", "value": "1 - 3 hours" }, { "name": "After effects", "value": "2 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Cycloalkylamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "rapidly develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": null, "crossTolerances": [ "dopamine", "stimulant" ] } }, { "url": "https://psychonautwiki.org/wiki/Proscaline", "name": "Proscaline", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "15 - 30 mg" }, { "name": "Common", "value": "30 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "After effects", "value": "3 - 5 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "no negative health effects attributed to trying this drug" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Psilocin", "name": "Psilocin", "aliases": [ "4-HO-DMT", "4-OH-DMT", "Psilocine", "Psilocyn", "Psilotsin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 15 mg" }, { "name": "Common", "value": "15 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 6 hours" }, { "name": "Onset", "value": "20 - 45 minutes" }, { "name": "Come up", "value": "1.5 - 3 hours" }, { "name": "Peak", "value": "2 - 3 hours" }, { "name": "Offset", "value": "1.5 - 2 hours" }, { "name": "After effects", "value": "4 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Psilocybe_cubensis", "name": "Psilocybe cubensis", "aliases": [ "Shrooms", "magic mushroom" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Pyrazolam", "name": "Pyrazolam", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.5 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 3 mg" }, { "name": "Strong", "value": "3 - 4 mg" }, { "name": "Heavy", "value": "4 mg +" } ], "duration": [ { "name": "Total", "value": "5 - 8 hours" }, { "name": "Onset", "value": "10 - 15 minutes" } ] } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Quetiapine", "name": "Quetiapine", "aliases": [ "Seroquel" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "10 mg" }, { "name": "Light", "value": "25 - 50 mg" }, { "name": "Common", "value": "50 - 150 mg" }, { "name": "Strong", "value": "150 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "4 - 8 hours" }, { "name": "Onset", "value": "20 - 40 minutes" }, { "name": "Peak", "value": "1.5 - 6 hours" }, { "name": "Offset", "value": "6 - 7 hours" }, { "name": "After effects", "value": "24 - 48 hours" } ], "bioavailability": "100% - 100%" } ], "data": { "class": { "chemical": [ "Dibenzothiazepine" ], "psychoactive": [ "Antipsychotic" ] }, "tolerance": { "full": "within a week of continuous use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity" ], "addictionPotential": "moderately physically and psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Risperidone", "name": "Risperidone", "aliases": [ "Risperdal" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "0.25 mg" }, { "name": "Light", "value": "0.5 - 1 mg" }, { "name": "Common", "value": "1 - 3 mg" }, { "name": "Strong", "value": "3 - 6 mg" }, { "name": "Heavy", "value": "6 mg +" } ], "duration": [ { "name": "Total", "value": "12 - 20 hours" }, { "name": "Onset", "value": "20 - 60 minutes" }, { "name": "Peak", "value": "2 - 8 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "12 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Benzisoxazole" ], "psychoactive": [ "Antipsychotic" ] }, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/SAM-e", "name": "SAM-e", "aliases": [ "Methylguanidoacetic acid", "S-Adenosyl methionine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "200 mg" }, { "name": "Light", "value": "400 - 800 mg" }, { "name": "Common", "value": "800 - 1200 mg" }, { "name": "Strong", "value": "1200 - 1600 mg" }, { "name": "Heavy", "value": "1600 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "100 - 180 minutes" } ], "bioavailability": "2-10%" } ], "data": { "class": { "chemical": [ "Nitrogenous_organic_acid" ], "psychoactive": [ "Nootropic" ] }, "tolerance": null, "toxicity": null, "addictionPotential": "not habit-forming with a low potential for abuse", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/STS-135", "name": "STS-135", "aliases": [], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "< 0.5 mg" }, { "name": "Light", "value": "0.5 - 1.5 mg" }, { "name": "Common", "value": "1.5 - 2 mg" }, { "name": "Strong", "value": "2 - 4 mg" }, { "name": "Heavy", "value": "4 mg +" } ], "duration": [ { "name": "Total", "value": "30 - 60 minutes" }, { "name": "Onset", "value": "10 - 45 seconds" }, { "name": "Come up", "value": "10 - 45 minutes" }, { "name": "Peak", "value": "10 - 30 minutes" }, { "name": "Offset", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "15 - 45 minutes" } ] } ], "data": { "class": { "chemical": [ "Adamantanes", "Indolecarboxamide" ], "psychoactive": [ "Cannabinoid" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "cannabinoids" ] } }, { "url": "https://psychonautwiki.org/wiki/Salvia_divinorum", "name": "Salvia divinorum", "aliases": [ "Sage of the Diviners", "Sally", "Salvia", "seer's sage", "ska mar\u00eda pastora", "yerba de la pastora" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Salvinorin_A", "name": "Salvinorin A", "aliases": [ "Diviner's Sage", "Sally", "Salvia", "Salvia divinorum", "Seer's Sage", "Ska Mar\u00eda Pastora" ], "roas": [ { "name": "Smoked", "dosage": null, "duration": [ { "name": "Total", "value": "15 - 90 minutes" }, { "name": "Onset", "value": "15 - 60 seconds" }, { "name": "After effects", "value": "15 - 60 minutes" } ] }, { "name": "Sublingual", "dosage": null, "duration": [ { "name": "Total", "value": "30 - 90 minutes" }, { "name": "Onset", "value": "10 - 20 minutes" }, { "name": "After effects", "value": "30 - 120 minutes" } ] } ], "data": { "class": { "chemical": [ "Terpenoid", "Salvinorin" ], "psychoactive": [ "Hallucinogens" ] }, "tolerance": null, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "hallucinogen" ] } }, { "url": "https://psychonautwiki.org/wiki/Secobarbital", "name": "Secobarbital", "aliases": [ "Seconal", "secobarbitone" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "20 mg" }, { "name": "Light", "value": "25 - 50 mg" }, { "name": "Common", "value": "50 - 150 mg" }, { "name": "Strong", "value": "150 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "15 - 60 minutes" }, { "name": "Peak", "value": "4 - 8 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "1 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Barbiturates" ], "psychoactive": [ "Depressant" ] }, "tolerance": null, "toxicity": [ "moderate toxicity" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Sufentanil", "name": "Sufentanil", "aliases": [ "Chronogesic,", "Sufenta", "sufentanyl" ], "roas": [ { "name": "Intravenous", "dosage": [ { "name": "Threshold", "value": "0.1 \u03bcg" }, { "name": "Light", "value": "1 - 5 \u03bcg" }, { "name": "Common", "value": "5 - 10 \u03bcg" }, { "name": "Strong", "value": "10 - 25 \u03bcg" }, { "name": "Heavy", "value": "25 \u03bcg +" } ], "duration": [ { "name": "Onset", "value": "1 - 2 minutes" }, { "name": "Peak", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "1 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Anilidopiperidine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": null, "zero": null }, "toxicity": [ "potentially fatal at heavy dosages", "potentially lethal when mixed with depressants like alcohol or benzodiazepines", "unintentionally spilling a very small amount of sufentanil on one's skin could result in a fatal overdose." ], "addictionPotential": "extremely addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/THJ-018", "name": "THJ-018", "aliases": [], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "< 1 mg" }, { "name": "Light", "value": "1 - 2 mg" }, { "name": "Common", "value": "2 - 3 mg" }, { "name": "Strong", "value": "3 - 5 mg" }, { "name": "Heavy", "value": "5 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 3 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "5 - 10 minutes" }, { "name": "After effects", "value": "60 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Naphthoylindazole" ], "psychoactive": [ "Cannabinoid" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "cannabinoids" ] } }, { "url": "https://psychonautwiki.org/wiki/THJ-2201", "name": "THJ-2201", "aliases": [], "roas": [ { "name": "Smoked", "dosage": [ { "name": "Threshold", "value": "< 0.5 mg" }, { "name": "Light", "value": "0.5 - 1 mg" }, { "name": "Common", "value": "1 - 2 mg" }, { "name": "Strong", "value": "2 - 5 mg" }, { "name": "Heavy", "value": "5 mg +" } ], "duration": [ { "name": "Total", "value": "1 - 2 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Peak", "value": "30 - 45 minutes" }, { "name": "Offset", "value": "0 - 0 minutes (Abrupt)" }, { "name": "After effects", "value": "60 - 90 minutes" } ] } ], "data": { "class": { "chemical": [ "Naphthoylindazole" ], "psychoactive": [ "Cannabinoid" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "exact toxic dosage is unknown" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "cannabinoids" ] } }, { "url": "https://psychonautwiki.org/wiki/TMA-2", "name": "TMA-2", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "20 - 120 minutes" }, { "name": "Come up", "value": "1.5 - 3 hours" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "Offset", "value": "2 - 4 hours" }, { "name": "After effects", "value": "4 - 24 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/TMA-6", "name": "TMA-6", "aliases": [], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 35 mg" }, { "name": "Strong", "value": "35 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "10 - 16 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Come up", "value": "1.5 - 3 hours" }, { "name": "Peak", "value": "5 - 8 hours" }, { "name": "Offset", "value": "3 - 5 hours" }, { "name": "After effects", "value": "6 - 18 hours" } ] } ], "data": { "class": { "chemical": [ "Amphetamine", "Substituted_amphetamines" ], "psychoactive": [ "Stimulants", "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } }, { "url": "https://psychonautwiki.org/wiki/Tabernanthe_iboga_(botany)", "name": "Tabernanthe iboga (botany)", "aliases": [ "Iboga" ], "roas": [], "data": { "class": null, "tolerance": null, "toxicity": null, "addictionPotential": null, "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Tapentadol", "name": "Tapentadol", "aliases": [ "Nucynta", "Palexia", "Yantil", "Yantil SR" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "12.5 mg" }, { "name": "Light", "value": "25 - 50 mg" }, { "name": "Common", "value": "50 - 75 mg" }, { "name": "Strong", "value": "75 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Onset", "value": "15 - 45 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "After effects", "value": "1 - 6 hours" } ] } ], "data": { "class": { "chemical": [ "Phenylpropylamine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Temazepam", "name": "Temazepam", "aliases": [ "Normison", "Restoril" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "5 - 10 mg" }, { "name": "Common", "value": "10 - 25 mg" }, { "name": "Strong", "value": "25 - 40 mg" }, { "name": "Heavy", "value": "40 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "20 - 90 minutes" }, { "name": "After effects", "value": "6 - 12 hour" } ], "bioavailability": "96%" } ], "data": { "class": { "chemical": [ "Benzodiazepines" ], "psychoactive": [ "Depressant" ] }, "tolerance": { "full": "within a couple of days of continuous use", "half": null, "zero": "7-14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/Theacrine", "name": "Theacrine", "aliases": [ "Temorine", "Temurin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 150 mg" }, { "name": "Strong", "value": "150 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "30 - 60 minutes" } ] }, { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Common", "value": "25 - 100 mg" } ], "duration": [ { "name": "Total", "value": "1 - 3 hours" }, { "name": "Onset", "value": "5 - 30 minutes" } ] } ], "data": { "class": { "chemical": [ "Xanthines", "Purine_alkaloid" ], "psychoactive": [ "Stimulants", "Nootropic" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": null, "addictionPotential": "produces dependence with chronic use and has a low abuse potential", "crossTolerances": [] } }, { "url": "https://psychonautwiki.org/wiki/Theanine", "name": "Theanine", "aliases": [ "L-Theanine", "L-\u03b3-glutamylethylamide and N5-ethyl-L-glutamine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "75 - 175 mg" }, { "name": "Common", "value": "175 - 300 mg" }, { "name": "Strong", "value": "300 - 500 mg" }, { "name": "Heavy", "value": "500 mg +" } ], "duration": [ { "name": "Total", "value": "3 - 6 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "1 - 3 hours" }, { "name": "After effects", "value": "6 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Amino_acid_analogue" ], "psychoactive": [ "Nootropic" ] }, "tolerance": { "full": "after prolonged and repeated usage", "half": "5 days", "zero": "10 days" }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "not habit-forming", "crossTolerances": [] } }, { "url": "https://psychonautwiki.org/wiki/Tianeptine", "name": "Tianeptine", "aliases": [ "Coaxil", "Stablon", "Tatinol" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "3 mg" }, { "name": "Light", "value": "6 - 12 mg" }, { "name": "Common", "value": "12 - 35 mg" }, { "name": "Strong", "value": "35 - 100 mg" }, { "name": "Heavy", "value": "100 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 3 hours" }, { "name": "Onset", "value": "30 - 60 minutes" }, { "name": "Come up", "value": "15 - 30 minutes" }, { "name": "Peak", "value": "60 - 90 minutes" }, { "name": "Offset", "value": "30 - 60 minutes" } ], "bioavailability": "99%" } ], "data": { "class": { "chemical": [ "Dibenzothiazepine", "Tricyclic_antidepressant" ], "psychoactive": [ "Nootropic", "Opioids" ] }, "tolerance": { "full": "with prolonged use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "large therapeutic index and margin of safety" ], "addictionPotential": "mildly addictive", "crossTolerances": [ "trycyclic antidepressants", "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Tramadol", "name": "Tramadol", "aliases": [ "Tadol", "Tramacur", "Tramal", "Tramundin" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "25 mg" }, { "name": "Light", "value": "50 - 100 mg" }, { "name": "Common", "value": "100 - 250 mg" }, { "name": "Strong", "value": "250 - 300 mg" }, { "name": "Heavy", "value": "300 mg +" } ], "duration": [ { "name": "Total", "value": "6 - 10 hours" }, { "name": "Onset", "value": "15 - 60 minutes" }, { "name": "Come up", "value": "30 - 60 minutes" }, { "name": "Peak", "value": "2 - 6 hours" }, { "name": "Offset", "value": "2 - 4 hours" } ], "bioavailability": "70 - 90%" } ], "data": { "class": { "chemical": [ "Phenylpropylamine" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Tyrosine", "name": "Tyrosine", "aliases": [ "L-Tyrosine or 4-hydroxyphenylalanine" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "300 mg" }, { "name": "Light", "value": "500 - 1000 mg" }, { "name": "Common", "value": "1000 - 2000 mg" }, { "name": "Strong", "value": "2000 - 3000 mg" }, { "name": "Heavy", "value": "3000 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 4 hours" }, { "name": "Onset", "value": "30 - 90 minutes" }, { "name": "Peak", "value": "1 - 3 hours" }, { "name": "After effects", "value": "6 - 12 hours" } ] } ], "data": { "class": { "chemical": [ "Amino_acid", "Substituted_phenethylamines" ], "psychoactive": [ "Stimulants" ] }, "tolerance": { "full": "after repeated and frequent usage", "half": "7 days", "zero": "14 days" }, "toxicity": [ "extremely low toxicity" ], "addictionPotential": "mildly habit forming", "crossTolerances": [ "dopamine" ] } }, { "url": "https://psychonautwiki.org/wiki/U-47700", "name": "U-47700", "aliases": [], "roas": [ { "name": "Insufflated", "dosage": [ { "name": "Threshold", "value": "1 mg" }, { "name": "Light", "value": "4 - 6 mg" }, { "name": "Common", "value": "6 - 8 mg" }, { "name": "Strong", "value": "8 - 10 mg" }, { "name": "Heavy", "value": "10 mg +" } ], "duration": [ { "name": "Total", "value": "2 - 3 hours" }, { "name": "Onset", "value": "5 - 10 minutes" }, { "name": "Come up", "value": "15 - 20 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Benzamide" ], "psychoactive": [ "Opioids" ] }, "tolerance": { "full": "develops with prolonged and repeated use", "half": "3 - 7 days", "zero": "1 - 2 weeks" }, "toxicity": [ "high toxicity relative to its dose due to its extreme potency", "potentially lethal when mixed with depressants like alcohol or benzodiazepines" ], "addictionPotential": "moderately addictive with a high potential for abuse", "crossTolerances": [ "opioids" ] } }, { "url": "https://psychonautwiki.org/wiki/Zolpidem", "name": "Zolpidem", "aliases": [ "Ambien", "Edluar", "Intermezzo", "Zolpimist" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 20 mg" }, { "name": "Common", "value": "20 - 30 mg" }, { "name": "Strong", "value": "30 - 50 mg" }, { "name": "Heavy", "value": "50 mg +" } ], "duration": [ { "name": "Total", "value": "60 - 120 minutes" }, { "name": "Onset", "value": "5 - 30 minutes" }, { "name": "Peak", "value": "1 - 2 hours" }, { "name": "Offset", "value": "5 - 15 minutes" }, { "name": "After effects", "value": "2 - 4 hours" } ] } ], "data": { "class": { "chemical": [ "Imidazopyridine" ], "psychoactive": [ "Hallucinogens", "Depressant" ] }, "tolerance": null, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like alcohol or opioids" ], "addictionPotential": "moderately addictive", "crossTolerances": null } }, { "url": "https://psychonautwiki.org/wiki/Zopiclone", "name": "Zopiclone", "aliases": [ "Imovane", "Zimovane" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "2 mg" }, { "name": "Light", "value": "3.5 - 5 mg" }, { "name": "Common", "value": "5 - 7.5 mg" }, { "name": "Strong", "value": "7.5 - 15 mg" }, { "name": "Heavy", "value": "15 mg +" } ], "duration": [ { "name": "Total", "value": "3.5 - 9 hours" }, { "name": "Onset", "value": "10 - 30 minutes" }, { "name": "Peak", "value": "3 - 4 hours" } ], "bioavailability": "52 - 59%" } ], "data": { "class": { "chemical": [ "Cyclopyrrolone" ], "psychoactive": [ "Hallucinogens", "Depressant" ] }, "tolerance": { "full": "within a couple of weeks of daily use", "half": null, "zero": "7 - 14 days" }, "toxicity": [ "low toxicity", "potentially lethal when mixed with depressants like benzodiazepines, alcohol or opioids" ], "addictionPotential": "extremely physically and psychologically addictive", "crossTolerances": [ "benzodiazepines" ] } }, { "url": "https://psychonautwiki.org/wiki/%CE%91MT", "name": "\u0391MT", "aliases": [ "AMT", "Indopan", "\u03b1MT" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "5 mg" }, { "name": "Light", "value": "10 - 25 mg" }, { "name": "Common", "value": "25 - 40 mg" }, { "name": "Strong", "value": "40 - 60 mg" }, { "name": "Heavy", "value": "60 - 80 mg" } ], "duration": [ { "name": "Total", "value": "13 - 15 hours" }, { "name": "Onset", "value": "60 - 180 minutes" }, { "name": "Peak", "value": "4 - 6 hours" }, { "name": "After effects", "value": "1 - 5 hours" } ] } ], "data": { "class": { "chemical": [ "Substituted_tryptamines" ], "psychoactive": [ "Psychedelics", "Entactogens" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "14 days", "zero": "1 month" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "moderately habit-forming", "crossTolerances": [ "psychedelics" ] } }, { "url": "https://psychonautwiki.org/wiki/%CE%92k-2C-B", "name": "\u0392k-2C-B", "aliases": [ "beta-keto 2C-B", "bk-2C-B", "\u03b2k-2C-B" ], "roas": [ { "name": "Oral", "dosage": [ { "name": "Threshold", "value": "50 mg" }, { "name": "Light", "value": "60 - 80 mg" }, { "name": "Common", "value": "80 - 100 mg" }, { "name": "Strong", "value": "100 - 150 mg" }, { "name": "Heavy", "value": "150 mg +" } ], "duration": [ { "name": "Total", "value": "8 - 12 hours" }, { "name": "Onset", "value": "20 - 70 minutes" } ] } ], "data": { "class": { "chemical": [ "Substituted_phenethylamines" ], "psychoactive": [ "Psychedelics" ] }, "tolerance": { "full": "almost immediately after ingestion", "half": "3 days", "zero": "7 days" }, "toxicity": [ "toxic dose is unknown" ], "addictionPotential": "not habit-forming", "crossTolerances": [ "psychedelic" ] } } ]