diff --git a/requirements.txt b/requirements.txt index dbad53d..9795b27 100644 --- a/requirements.txt +++ b/requirements.txt @@ -1,2 +1,4 @@ rasa -pandas \ No newline at end of file +pandas +beautifulsoup4 +python-graphql-client diff --git a/tripsit/getAllDrugs.json b/tripsit/getAllDrugs.json deleted file mode 100644 index 590f895..0000000 --- a/tripsit/getAllDrugs.json +++ /dev/null @@ -1,35201 +0,0 @@ -{ - "yopo": { - "name": "yopo", - "properties": { - "summary": "Anadenanthera peregrina, also known as yopo, is a perennial tree native to the Caribbean and South America. It is an entheogen containing 5-MeO-DMT and DMT, and is used in healing ceremonies and rituals. It is also a source of dietary calcium.", - "aliases": [ - "anadenanthera", - "\"anadenanthera" - ], - "categories": [ - "empathogen", - "psychedelic" - ] - }, - "pretty_name": "YOPO", - "aliases": [ - "anadenanthera", - "\"anadenanthera" - ], - "categories": [ - "empathogen", - "psychedelic" - ], - "id": 0 - }, - "pyrazolam": { - "name": "pyrazolam", - "properties": { - "summary": "RC benzodiazepine discovered by Hoffman-LaRoche in the 1970s. Came to the RC market in the early 2010s. At lower doses it is mainly an anxiolytic compound, yet at higher doses can be quite sedating, hypnotic, amnesic, and can cause loss of inhibitions. Structurally similar to Alprazolam, Bromazepam, and Triazolam. Is 12x as potent as Diazepam.", - "duration": "Oral: 5-8 hours. | Insufflated: 3-5 hours.", - "dose": "Oral Light: 1-2mg Common: 2-3mg Strong: 3-4mg's.", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "onset": "Oral: 10-15 minutes. | Insufflated: 5 minutes.", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia.", - "after-effects": "1-12 hours.", - "dose_to_diazepam": "Pyrazolam - 10-20mg ~=10mg Diazepam." - }, - "pretty_name": "Pyrazolam", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "1-2mg", - "Common": "2-3mg", - "Strong": "3-4mg" - } - }, - "formatted_duration": { - "Oral": "5-8", - "Insufflated": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-15", - "Insufflated": "5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Pyrazolam.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 1 - }, - "1b-lsd": { - "name": "1b-lsd", - "properties": { - "summary": "1B-LSD (1-butanoyl-lysergic acid diethylamide) is an LSD analogue which appears to be about as potent as 1P-LSD (slightly more potent than LSD) and has a slightly shorter duration than that of LSD, again thought to be about the same as 1P-LSD. Released in late 2018, and marketed agressively as a replacement for 1P-LSD. 1B-LSD does not yet have a clearly established safety profile,", - "aliases": [ - "1b" - ], - "dose": "Oral Light: 25-50ug Common: 50-125ug's Strong: 125-250ug's. | NOTE: At the time of this chemical's release, the manufacturers claimed 1B-LSD was expected to be slightly less potent than 1P-LSD, supposedly owing to the increased mass of the butanoyl group over the propionyl group, however anecdotes seem to indicate approximate equipotency to 1P-LSD.", - "duration": "8-12 hours", - "onset": "45-90 minutes", - "after-effects": "6-24 hours", - "categories": [ - "tentative", - "research-chemical", - "psychedelic" - ] - }, - "pretty_name": "1B-LSD", - "aliases": [ - "1b" - ], - "categories": [ - "tentative", - "research-chemical", - "psychedelic" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50ug", - "Common": "50-125ug", - "Strong": "125-250ug" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "dose_note": " NOTE: At the time of this chemical's release, the manufacturers claimed 1B-LSD was expected to be slightly less potent than 1P-LSD, supposedly owing to the increased mass of the butanoyl group over the propionyl group, however anecdotes seem to indicate approximate equipotency to 1P-LSD.", - "id": 2 - }, - "3-fmc": { - "name": "3-fmc", - "properties": { - "dose": "Light: 25-50mg Common: 50-100mg Strong: 100-150mg | NOTE: 3-fmc is very harsh on the nasal membranes", - "duration": "2-4 hours.", - "summary": "A stimulant drug related to mephedrone. A member of the cathinone class, it is also an amphetamine. Effects similar to other drugs of its class, may possess high addiction potential. May be a monoamine releaser, reuptake inhibitor or both.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "onset": "Rapid.", - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness." - }, - "pretty_name": "3-FMC", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Light:": { - "Light": "25-50mg", - "Common": "50-100mg", - "Strong": "100-150mg" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Rapid." - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "dose_note": " NOTE: 3-fmc is very harsh on the nasal membranes", - "sources": { - "_general": [ - "3-FMC is a monoamine releaser - International Review of Neurobiology - The Neuropsychiatric Complications of Stimulant Abuse Vol. 20" - ] - }, - "id": 3 - }, - "ibuprofen": { - "name": "ibuprofen", - "properties": { - "summary": "A ubiquitously available pain reliever/fever reducer. Ibuprofen is a nonsteroidal anti-inflammatory drug, available in many forms. It is sometimes used to reduce the body-load caused by certain drugs, such as stimulants.", - "duration": "4-6 hours. ER forumulations up to 12 hours.", - "onset": "within an hour.", - "avoid": "Alcoholic beverages.", - "dose": "Common: 400-800mg's.", - "categories": [ - "common" - ] - }, - "pretty_name": "Ibuprofen", - "categories": [ - "common" - ], - "formatted_dose": { - "Oral": { - "Common": "400-800mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "within" - }, - "sources": { - "_general": [ - "Ibuprofen: pharmacology, efficacy and safety - http://www.ncbi.nlm.nih.gov/pubmed/19949916", - "Coronary arterial vasodilator effect of ibuprofen - http://www.ncbi.nlm.nih.gov/pubmed/7053413" - ] - }, - "id": 4 - }, - "fluorolintane": { - "name": "fluorolintane", - "properties": { - "summary": "A dissociative anaesthetic also known as 2-FPPP, very little is known about this obscure and rare drug. Reported by some to be stimulating, having effects similar to other dissociative drugs such as PCP and ketamine.", - "dose": "Oral Light: 75-100mg Common: 100-150mg Strong: 150-250mg Heavy: 250mg+.", - "duration": "3-6 hours", - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "dissociative" - ], - "onset": "15-45 minutes.", - "after-effects": "2-6 hours." - }, - "pretty_name": "Fluorolintane", - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "dissociative" - ], - "formatted_dose": { - "Oral": { - "Light": "75-100mg", - "Common": "100-150mg", - "Strong": "150-250mg", - "Heavy": "250mg+." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "id": 5 - }, - "clonitazene": { - "name": "clonitazene", - "properties": { - "summary": "An opioid that is roughly three times as potent as Morphine. Is related to Etonitazene, which is about 1000-1500x the potency of Morphine.", - "dose": "Oral Light: 2.5-5mg Commong: 5-10mg Strong: 10-15mg+", - "onset": "Oral: 10-30 minutes.", - "duration": "Oral: 4-8 hours.", - "after-effects": "1-8 hours.", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "research-chemical" - ] - }, - "pretty_name": "Clonitazene", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Commong": "5-10mg", - "Strong": "10-15mg+" - } - }, - "formatted_duration": { - "Oral": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 6 - }, - "mephedrone": { - "name": "mephedrone", - "properties": { - "summary": "A shortlived euphoric stimulant, developed as an analogue of MDMA, which was extremely popular in the research chemical scene before being banned. Commonly seen on street markets but rarer online. Very strong urge to redose compulsively.", - "dose": "Oral Light: 50-100mg Common: 100-200mg Strong: 150-300mg Heavy: 300mg+ | Insufflated Light: 15-25mg Common: 20-80mg Strong: 75-125mg Heavy: 125mg+", - "effects": "Generally described as being more intense of a stimulant than MDMA but with somewhat less of an empathogenic feel.", - "onset": "15-45 minutes", - "duration": "2-3 hours", - "detection": "Mixed reports on whether the drug shows positive on standard drug tests.", - "aliases": [ - "4-mmc", - "meow", - "m-cat", - "4-methylmethcathinone", - "4mmc" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ], - "after-effects": "6-24 hours" - }, - "pretty_name": "Mephedrone", - "aliases": [ - "4-mmc", - "meow", - "m-cat", - "4-methylmethcathinone", - "4mmc" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-200mg", - "Strong": "150-300mg", - "Heavy": "300mg+" - }, - "Insufflated": { - "Light": "15-25mg", - "Common": "20-80mg", - "Strong": "75-125mg", - "Heavy": "125mg+" - } - }, - "formatted_duration": { - "value": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Generally described as being more intense of a stimulant than MDMA but with somewhat less of an empathogenic feel", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4Methylmethcathinone.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Body odor alteration": "https://psychonautwiki.org/wiki/Body_odor_alteration", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Ego inflation": "https://psychonautwiki.org/wiki/Ego_inflation", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Vibrating vision": "https://psychonautwiki.org/wiki/Vibrating_vision", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Mephedrone toxicity has been clinically associated with seizures - http://emj.bmj.com/content/28/4/280.short" - ] - }, - "id": 7 - }, - "valerylfentanyl": { - "name": "valerylfentanyl", - "properties": { - "summary": "Opioid that is a higher homologue of Butyrfentanyl with greatly reduced potency.", - "categories": [ - "opioid", - "depressant", - "research-chemical", - "tentative", - "habit-forming" - ], - "dose": "Light: 50+mg", - "aliases": [ - "vf" - ] - }, - "pretty_name": "Valerylfentanyl", - "aliases": [ - "vf" - ], - "categories": [ - "opioid", - "depressant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50+mg" - } - }, - "id": 8 - }, - "4-ho-dipt": { - "name": "4-ho-dipt", - "properties": { - "summary": "A psychedelic tryptamine also known as iprocin. A homologue of psilocin, this drug likely has similar effects to psychedelic mushrooms. Said to have a rapid onset and relatively short duration for a drug of its class.", - "aliases": [ - "iprocin" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "dose": "Threshold: 3-5mg Light: 5-10mg Common: 10-20mg Strong: 20-30mg+", - "onset": "20-60 minutes.", - "duration": "2-4 hours.", - "after-effects": "1-6 hours." - }, - "pretty_name": "4-HO-DiPT", - "aliases": [ - "iprocin" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3-5mg", - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-30mg+" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4HODiPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal17.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 9 - }, - "deschloroketamine": { - "name": "deschloroketamine", - "properties": { - "summary": "A novel analogue of Ketamine which is much more potent and has a longer duration.", - "dose": "Light: 5-15mg Common: 15-25mg Strong: 25-40mg Heavy: 40+mg.", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "2'-oxo-pcm", - "dxe", - "dck", - "o-pcm", - "opcm", - "2-oxo-pcm" - ], - "duration": "3-6 hours", - "onset": "Insufflated: 2-20 minutes.", - "after-effects": "1-8 hours." - }, - "pretty_name": "Deschloroketamine", - "aliases": [ - "2'-oxo-pcm", - "dxe", - "dck", - "o-pcm", - "opcm", - "2-oxo-pcm" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-25mg", - "Strong": "25-40mg", - "Heavy": "40+mg." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "2-20", - "_unit": "minutes" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection", - "Visual sliding": "https://psychonautwiki.org/wiki/Visual_sliding" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 10 - }, - "dmt": { - "name": "dmt", - "properties": { - "summary": "A popular and powerful psychedelic, typically used in two ways; either it is vapourised for a short 'breakthrough' experience, or it is taken in combination with an enzyme inhibitor for a long, intense trip (this is also known as ayahuasca or pharmahuasca).", - "onset": "Vaporized/smoked: 0-2 minutes | Oral_MAOI: 20-45 minutes | Insufflated: 3-5 minutes", - "dose": "Vapourised Threshold: 5-10mg Light: 10-15mg Common: 15-25mg Strong: 25-35mg Heavy: 35mg+ | Insufflated Light: 10-25mg Common: 25-50mg Strong: 50-125mg+ | Intravenous Light: 10-15mg Common: 15-25mg Strong: 25-40mg", - "duration": "Vaporized/smoked: 3-10 minutes | Oral_MAOI: 180-420 minutes | Insufflated: 45-60 minutes", - "effects": "immersive experience, open eye visuals, radical perspective shifting, profound life-changing spiritual experiences, powerful rushing of sensation, change in perception of time, auditory hallucinations, color shifting, hard on lungs when smoking, stomach discomfort, difficulty integrating experiences, overwhelming fear", - "after-effects": "15-60 minutes", - "aliases": [ - "n,n-dmt", - "dimethyltryptamine" - ], - "molecule": "http://www.erowid.org/chemicals/dmt/images/archive/dmt_3d_mid.jpg", - "marquis": "Orange", - "categories": [ - "psychedelic", - "common" - ], - "vaporization": "60-80C (140-176F)", - "half-life": "10-20 minutes" - }, - "pretty_name": "DMT", - "aliases": [ - "n,n-dmt", - "dimethyltryptamine" - ], - "categories": [ - "psychedelic", - "common" - ], - "formatted_dose": { - "Vapourised": { - "Threshold": "5-10mg", - "Light": "10-15mg", - "Common": "15-25mg", - "Strong": "25-35mg", - "Heavy": "35mg+" - }, - "Insufflated": { - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-125mg+" - }, - "Intravenous": { - "Light": "10-15mg", - "Common": "15-25mg", - "Strong": "25-40mg" - } - }, - "formatted_duration": { - "Vaporized/smoked": "3-10", - "Oral_MAOI": "180-420", - "Insufflated": "45-60", - "_unit": "minutes" - }, - "formatted_onset": { - "Vaporized/smoked": "0-2", - "Oral_MAOI": "20-45", - "Insufflated": "3-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "immersive experience", - "open eye visuals", - "radical perspective shifting", - "profound life-changing spiritual experiences", - "powerful rushing of sensation", - "change in perception of time", - "auditory hallucinations", - "color shifting", - "hard on lungs when smoking", - "stomach discomfort", - "difficulty integrating experiences", - "overwhelming fear" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DMT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal06.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour replacement": "https://psychonautwiki.org/wiki/Colour_replacement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/Exposure_to_inner_mechanics_of_consciousness", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Feelings of impending doom": "https://psychonautwiki.org/wiki/Feelings_of_impending_doom", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Machinescapes": "https://psychonautwiki.org/wiki/Machinescapes", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Recursion": "https://psychonautwiki.org/wiki/Recursion", - "Rejuvenation": "https://psychonautwiki.org/wiki/Rejuvenation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness" - }, - "formatted_aftereffects": { - "value": "15-60", - "_unit": "minutes" - }, - "dose_note": " NOTE: These figures are for 100% effective vaporization methods. Most methods are not 100% effective. Likelyhood of having a \"breakthrough\" experience increases with dose.", - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Low Risk & Synergy" - }, - "nbomes": { - "status": "Low Risk & Synergy" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Low Risk & Synergy" - }, - "amt": { - "status": "Low Risk & Synergy" - }, - "5-meo-xxt": { - "status": "Low Risk & Synergy" - }, - "cannabis": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & Synergy" - }, - "pcp": { - "status": "Low Risk & Synergy" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "mdma": { - "status": "Low Risk & Synergy" - }, - "cocaine": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "caffeine": { - "status": "Low Risk & No Synergy" - }, - "alcohol": { - "status": "Low Risk & Decrease" - }, - "ghb/gbl": { - "status": "Low Risk & Decrease" - }, - "opioids": { - "status": "Low Risk & No Synergy" - }, - "tramadol": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures." - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Low Risk & Synergy" - }, - "ssris": { - "status": "Low Risk & Decrease" - } - }, - "id": 11 - }, - "morphine": { - "name": "morphine", - "properties": { - "summary": "The prototypical opioid drug, a powerful analgesic with euphoric qualities, found in the seeds and wax of the plant papaver somniferum (opium poppy). First isolated by Friedrich Sertürner in 1805, named for its sleep-inducing qualities. Do not combine with other depressants, may cause dangerous respiratory depression in overdose.", - "onset": "Oral_IR: 10-30 minutes | Oral_ER: 40-80 minutes | Insufflated: 10-30 minutes | Plugged: 10-30 minutes | IV/IM: 0-1 minutes.", - "duration": "Oral_IR: 4-6 hours | Oral_ER: 4-10 hours | Insufflated: 4-5 hours | Plugged: 3-4 hours | IV/IM: 2-4 hours.", - "categories": [ - "opioid", - "habit-forming", - "common", - "depressant" - ], - "dose": "Oral Light: 5mg-10mg Common: 15-20mg Strong: 30mg+", - "bioavailability": "Oral 30% | Insufflated 15-20% | Rectal 30% NOTE: Chitosan (A linear polysaccharide that helps absorb drugs better) increases the insufflated bioavailabilty to around 60%. Ratio used was 1.3 grams : 6.7 grams (Morphine:Chitosan) Use with caution.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Morphine", - "categories": [ - "opioid", - "habit-forming", - "common", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "5mg-10mg", - "Common": "15-20mg", - "Strong": "30mg+" - } - }, - "formatted_duration": { - "Oral_IR": "4-6", - "Oral_ER": "4-10", - "Insufflated": "4-5", - "Plugged": "3-4", - "IV/IM": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral_IR": "10-30", - "Oral_ER": "40-80", - "Insufflated": "10-30", - "Plugged": "10-30", - "IV/IM": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Morphine.shtml" - }, - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Codeine analgesia is due to codeine-6-glucuronide, not morphine. - https://www.ncbi.nlm.nih.gov/pubmed/11092114", - "Dextromethorphan potentiates the antinociceptive effects of morphine and the delta-opioid agonist SNC80 in squirrel monkeys. - http://www.ncbi.nlm.nih.gov/pubmed/11805202", - "Magnesium increases morphine analgesic effect in different experimental models of pain. - http://www.ncbi.nlm.nih.gov/pubmed/11873038", - "Identification of CYP3A4 and CYP2C8 as the major cytochrome P450 s responsible for morphine N-demethylation in human liver microsomes. - http://www.ncbi.nlm.nih.gov/pubmed/12936704", - "4-Caffeoyl-1,5-quinide in roasted coffee inhibits [3H]naloxone binding and reverses anti-nociceptive effects of morphine in mice. - http://www.ncbi.nlm.nih.gov/pubmed/15088081", - "Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice. - http://www.ncbi.nlm.nih.gov/pubmed/18819620", - "Enhancement by grapefruit juice of morphine antinociception. - http://www.ncbi.nlm.nih.gov/pubmed/19043223", - "Low-Dose Cannabinoid Type 2 Receptor Agonist Attenuates Tolerance to Repeated Morphine Administration via Regulating μ-Opioid Receptor Expression i... - http://www.ncbi.nlm.nih.gov/pubmed/26720619", - "Influence of a high-fat meal on the absorption of morphine from oral solutions. - http://www.ncbi.nlm.nih.gov/pubmed/2791448", - "Discriminative stimulus effects of reversible and irreversible opiate agonists: morphine, oxymorphazone and buprenorphine. - http://www.ncbi.nlm.nih.gov/pubmed/6206224", - "Endogenous codeine and morphine in poor and extensive metabolisers of the CYP2D6 (debrisoquine/sparteine) polymorphism. - http://www.ncbi.nlm.nih.gov/pubmed/8113966", - "The effect of food intake on the pharmacokinetics of sustained-release morphine sulfate capsules. - http://www.ncbi.nlm.nih.gov/pubmed/9152568" - ] - }, - "id": 12 - }, - "4-fma": { - "name": "4-fma", - "properties": { - "summary": "A stimulant with some empathogenic properties, and analogue of Methamphetamine with similar effects. Reported to be less effective than 2-FMA and related compounds. Little is known about the pharmacological effects of this compound. Not to be confused with 4-FA, which has a different effect profile, despite similar potency.", - "duration": "3-5 hours.", - "dose": "Oral Light: 50-75mg's Common: 75-125mg's Heavy: 125-200mg+", - "onset": "Oral: 20-40 minutes | Insufflated: 5-10 minutes", - "after-effects": "1-6 hours.", - "aliases": [ - "4-fluromethamphetamine", - "4fma" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness." - }, - "pretty_name": "4-FMA", - "aliases": [ - "4-fluromethamphetamine", - "4fma" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "50-75mg", - "Common": "75-125mg", - "Heavy": "125-200mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-40", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 13 - }, - "5-iai": { - "name": "5-iai", - "properties": { - "summary": "A monoamine triple releaser first synthesised by David Nichols, possesses similar properties to MDMA. Probably neurotoxic in humans, however the extent of this is unclear.", - "aliases": [ - "5iai" - ], - "warning": "Note: It seems /most/ of the market for this drug is infact largely falsified.", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "after-effects": "1-24 hours." - }, - "pretty_name": "5-IAI", - "aliases": [ - "5iai" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen" - ], - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 14 - }, - "cialis": { - "name": "cialis", - "properties": { - "summary": "Tadalafil, a PDE5 inhibitor used to combat erectile disfunction. Dangerous in combination with other drugs which lower blood pressure.", - "dose": "Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg.", - "duration": "4-6 hours." - }, - "pretty_name": "Tadalafil", - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg." - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "id": 15 - }, - "methaqualone": { - "name": "methaqualone", - "properties": { - "summary": "A pharmaceutical depressant and sedative phased out due to the better safety profile of benzodiazepines, part of the Qualone group of substances. Now very rare, except in South Africa.", - "dose": "Oral Light: 75-150mg Common: 150-300mg Strong: 300mg+ | NOTE: Do not take more than 300mg without a tolerance.", - "onset": "30-45 minutes", - "duration": "5-8 hours.", - "after-effects": "4-6 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "depressant", - "habit-forming" - ], - "aliases": [ - "ludes", - "quaaludes", - "qualudes", - "mandrax" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic." - }, - "pretty_name": "Methaqualone", - "aliases": [ - "ludes", - "quaaludes", - "qualudes", - "mandrax" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "75-150mg", - "Common": "150-300mg", - "Strong": "300mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methaqualone.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection" - }, - "formatted_aftereffects": { - "value": "4-6", - "_unit": "hours" - }, - "dose_note": " NOTE: Do not take more than 300mg without a tolerance.", - "id": 16 - }, - "aspirin": { - "name": "aspirin", - "properties": { - "summary": "A widely used anti-inflammatory and blood-thinner produced by acetylation of the naturally occurring salicyclic acid. Part of the nonsteroidal antiinflammatory class of drugs, a cyclooxygenase inhibitor. Very common over-the-counter pain reliever and fever reducer. Also used in smaller doses to lower risk of heart attack.", - "onset": "30-90 minutes.", - "duration": "(Dose-Dependent) 2-3h (for low doses), 15-30h (for large doses)", - "effects": "Analgesia, Antipyresis, Anti-inflammation, Antiaggregation", - "avoid": "Acetazolamide, Ammonium Chloride, Alcohol, Tolbutamide, Chlorpropamide, Warfarin, Methotrexate, Phenytoin, Probenecid, Valproic Acid, Other NSAIDs, Corticosteroids, Spironolactone, Penicillin G, Vitamin C", - "dose": "Oral Threshold: 50mg Light: 75mg-81mg Common: 325mg-650mg Heavy: 1.6g | NOTE: Aspirin is known to be dangerous in dosages of 4g and above", - "aliases": [ - "acetylsalicylate" - ], - "categories": [ - "common" - ], - "bioavailability": "Oral: 55.8-74%." - }, - "pretty_name": "Aspirin", - "aliases": [ - "acetylsalicylate" - ], - "categories": [ - "common" - ], - "formatted_dose": { - "Oral": { - "Threshold": "50mg", - "Light": "75mg-81mg", - "Common": "325mg-650mg", - "Heavy": "1.6g" - } - }, - "formatted_duration": { - "value": "Dose-Dependent" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Analgesia", - "Antipyresis", - "Anti-inflammation", - "Antiaggregation" - ], - "dose_note": " NOTE: Aspirin is known to be dangerous in dosages of 4g and above", - "id": 17 - }, - "dimemebfe": { - "name": "dimemebfe", - "properties": { - "summary": "Related in structure to 5-MeO-DMT, yet much less potent. Described as feeling somewhat similar to mushrooms, with some empathogenic effects.", - "dose": "Light: 25-50mg Common: 50-75mg Strong: 75-125mg.", - "duration": "4-6 hours.", - "onset": "10-40 minutes.", - "categories": [ - "research-chemical", - "psychedelic", - "empathogen", - "tentative" - ], - "aliases": [ - "5-meo-bfe" - ] - }, - "pretty_name": "Dimemebfe", - "aliases": [ - "5-meo-bfe" - ], - "categories": [ - "research-chemical", - "psychedelic", - "empathogen", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50mg", - "Common": "50-75mg", - "Strong": "75-125mg." - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-40", - "_unit": "minutes" - }, - "id": 18 - }, - "naphyrone": { - "name": "naphyrone", - "properties": { - "summary": "A drug derived from pyrovalerone which acts as a TRI, producing stimulating effects. Had been sold in a blend called \"NRG-1\" Little information exists about the safety profile of this drug.", - "onset": "Within 30 minutes.", - "duration": "6-12 hours (Very dependant on dose)", - "dose": "(Tentative) Oral: Light: 10-20mg Common: 20-35mg Strong: 35-50mg+", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ] - }, - "pretty_name": "Naphyrone", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "(Tentative)": { - "Oral": "Light", - "Common": "20-35mg", - "Strong": "35-50mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Within", - "_unit": "minutes" - }, - "id": 19 - }, - "librium": { - "name": "librium", - "properties": { - "summary": "Chlordiazepoxide, a medium-acting benzodiazepine drug prescribed mostly for sleep purposes. Sedative and hypnotic, it may cause lowered inhibitions and amnesia in high doses.", - "dose": "Light: 5-10mg Common: 10-20mg Heavy: 20-40mg+ | NOTE: 25mg of Librium is approximately equal to 10mg of Diazepam", - "onset": "20-40 minutes", - "duration": "6-10 hours", - "avoid": "All other CNS depressants", - "aliases": [ - "chlordiazepoxide" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "bioavailability": "Oral 100% | Intramuscular 90-95%", - "after-effects": "1-14 hours.", - "dose_to_diazepam": "25mg ~=10mg Diazepam" - }, - "pretty_name": "Librium", - "aliases": [ - "chlordiazepoxide" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Light:": { - "Light": "5-10mg", - "Common": "10-20mg", - "Heavy": "20-40mg+" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-14", - "_unit": "hours" - }, - "dose_note": " NOTE: 25mg of Librium is approximately equal to 10mg of Diazepam", - "sources": { - "_general": [ - "Alcohol and benzodiazepines in fatal poisonings. - https://www.ncbi.nlm.nih.gov/pubmed/12170103" - ] - }, - "id": 20 - }, - "3-meo-pcp": { - "name": "3-meo-pcp", - "properties": { - "summary": "A potent dissociative often compared to MXE but with a longer duration, much less sedating effects and causing an overall different experience. Users have reported effects as being similar to PCP. Roughtly ten times more potent than 4-MeO-PCP.", - "dose": "Oral Threshold: 1.5-3mg Light: 3-5mg Common: 5-10mg. Strong: 10-15mg Heavy: 15-18mg+ | Insufflated Threshold: 1-2mg Light: 2-5mg Common: 5-8mg Strong: 8-12mg Heavy: 12-15mg+", - "duration": "Oral: 3-5 hours +/- an hour dependant on dose. | Insufflated: 2-4 hours +/- ~30 minutes, dependant on dose.", - "onset": "Oral: 20-90 minutes. | Insufflated: 10-30 minutes. | IM: 3-7 minutes.", - "after-effects": "2-48 hours.", - "aliases": [ - "3meopcp" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "common" - ] - }, - "pretty_name": "3-MeO-PCP", - "aliases": [ - "3meopcp" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Threshold": "1.5-3mg", - "Light": "3-5mg", - "Common": "5-10mg.", - "Strong": "10-15mg", - "Heavy": "15-18mg+" - }, - "Insufflated": { - "Threshold": "1-2mg", - "Light": "2-5mg", - "Common": "5-8mg", - "Strong": "8-12mg", - "Heavy": "12-15mg+" - } - }, - "formatted_duration": { - "Oral": "3-5", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-90", - "Insufflated": "10-30", - "IM": "3-7", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_3MeOPCP.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "Feelings of impending doom": "https://psychonautwiki.org/wiki/Feelings_of_impending_doom", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Mania": "https://psychonautwiki.org/wiki/Mania", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Psychosis": "https://psychonautwiki.org/wiki/Psychosis", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement" - }, - "formatted_aftereffects": { - "value": "2-48", - "_unit": "hours" - }, - "id": 21 - }, - "eth-lad": { - "name": "eth-lad", - "properties": { - "summary": "A psychedelic drug and slightly more potent analogue of LSD, first synthesised by Alexander Shulgin - sometimes described as being less 'abrasive' than LSD. Less common than the associated AL-LAD, though has seen some popularity since its release on the Internet research chemical scene in 2015.", - "dose": "Oral Threshold: 20-30ug Light: 30-60ug Common: 60-100ug Strong: 100-200ug+", - "duration": "6-14 hours", - "onset": "15-90 minutes", - "categories": [ - "research-chemical", - "psychedelic" - ], - "after-effects": "1-12 hours.", - "aliases": [ - "ethlad" - ] - }, - "pretty_name": "ETH-LAD", - "aliases": [ - "ethlad" - ], - "categories": [ - "research-chemical", - "psychedelic" - ], - "formatted_dose": { - "Oral": { - "Threshold": "20-30ug", - "Light": "30-60ug", - "Common": "60-100ug", - "Strong": "100-200ug+" - } - }, - "formatted_duration": { - "value": "6-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-90", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_ETHLAD.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal12.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 22 - }, - "3-fa": { - "name": "3-fa", - "properties": { - "summary": "A stimulant that is close to equipotent with methamphetamine and acts as a monoamine releasing agent , but has more selectivity for dopamine/noradrenaline over serotonin.", - "onset": "30-90 minutes (oral) depending on stomach contents.", - "duration": "4-6 hours", - "dose": "Oral Light: 5-15mg Common: 15-30mg Strong: 30-60mg+", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "after-effects": "1-6 hours.", - "aliases": [ - "3fa" - ] - }, - "pretty_name": "3-FA", - "aliases": [ - "3fa" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-60mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 23 - }, - "aet": { - "name": "aet", - "properties": { - "aliases": [ - "alpha-ethyl-tryptamine", - "a-et", - "a-ethyltryptamine" - ], - "onset": "60-120 minutes.", - "duration": "5-10 hours.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "tentative", - "empathogen" - ], - "summary": "A quite rare substance of the tryptamine class, was first made by Upjohn as an antidepressant. Please use extreme caution if you get the pleasure of trying this drug.", - "dose": "Light: 80-100mg Common: 100-125mg Strong: 125-150mg+", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-efects": "1-6 hours.", - "after-effects": "1-24 hours.", - "avoid": "It can induce serotonergic neurotoxicity similar to the likes of MDMA. Do not combine this drug if you take an MAOi." - }, - "pretty_name": "αET", - "aliases": [ - "alpha-ethyl-tryptamine", - "a-et", - "a-ethyltryptamine" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "tentative", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "80-100mg", - "Common": "100-125mg", - "Strong": "125-150mg+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_AET.shtml" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 24 - }, - "tetrahydrofuran-fentanyl": { - "name": "tetrahydrofuran-fentanyl", - "properties": { - "summary": "An analogue of fentanyl that is unknown in literature. Is most likely less potent than most other analogues. Yet very few reports are around. Be careful.", - "aliases": [ - "thf-f", - "thff" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant", - "research-chemical" - ] - }, - "pretty_name": "TETRAHYDROFURAN-FENTANYL", - "aliases": [ - "thf-f", - "thff" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant", - "research-chemical" - ], - "id": 25 - }, - "bromantane": { - "name": "bromantane", - "properties": { - "summary": "An unusual stimulant and anxiolytic drug with dopamine and serotonin reuptake inhibition properties. Infamously used as a doping agent in the 1996 Olympics. There are some concerns it may exacerbate the underlying causes of Alzheimer's disease.", - "dose": "Oral Light: 50-100mg Common: 100-200mg Strong: 200-400mg+ | NOTE: Anticholinergic effects at high doses (around 500mg)", - "onset": "Oral: 10-30 minutes.", - "duration": "4-8 hours.", - "categories": [ - "depressant", - "stimulant", - "research-chemical", - "nootropic" - ], - "bioavailabity": "Oral: 42%.", - "after-effects": "1-10 hours." - }, - "pretty_name": "Bromantane", - "categories": [ - "depressant", - "stimulant", - "research-chemical", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-200mg", - "Strong": "200-400mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "_unit": "minutes" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Stamina enhancement": "https://psychonautwiki.org/wiki/Stamina_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "dose_note": " NOTE: Anticholinergic effects at high doses (around 500mg)", - "id": 26 - }, - "ephedrine": { - "name": "ephedrine", - "properties": { - "summary": "Ephedrine is a sympathomimetic amine commonly used as a stimulant, concentration aid, decongestant, appetite suppressant, and to treat hypotension associated with anaesthesia. A methamphetamine analogue and commonly used in the production of methamphetamine.", - "duration": "3 - 6 hours", - "adverse-effects": "Tachycardia, cardiac arrhythmias, angina pectoris, vasoconstriction with hypertension, flushing, sweating, acne vulgaris, nausea, decreased urination, difficulty urinating, restlessness, confusion, insomnia, mild euphoria, mania/hallucinations, delusions, formication, dyspnea, pulmonary edema, dizziness, headache, tremor, hyperglycemic reactions, and dry mouth", - "contraindictions": "Closed-angle glaucoma, phaeochromocytoma, asymmetric septal hypertrophy (idiopathic hypertrophic subaortic stenosis), concomitant or recent (previous 14 days) monoamine oxidase inhibitor (MAOI) therapy, general anaesthesia with halogenated hydrocarbons (particularly halothane), tachyarrhythmias or ventricular fibrillation, and hypersensitivity to ephedrine", - "pharmacology": "NDRA (Norepinephrine-Dopamine Releasing Agent)", - "pharmacokinetics": "Bioavailability: 85% | Metabolism: minimal hepatic | Excretion: 22 - 99% renal", - "legal": "Australia: Prescription Only (S4) | Canada: Schedule VI | United Kingdom: P | United States: List I OTC", - "category": "Stimulant", - "categories": [ - "stimulant", - "habit-forming" - ], - "dose": "Oral Threshold: 5-10mg Light: 10-20mg Common: 20-30mg Strong: 30-50mg Heavy: 50mg+", - "onset": "5-20 minutes.", - "after-effects": "1-8 hours." - }, - "pretty_name": "Ephedrine", - "categories": [ - "stimulant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Light": "10-20mg", - "Common": "20-30mg", - "Strong": "30-50mg", - "Heavy": "50mg+" - } - }, - "formatted_duration": { - "value": "3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-20", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ephedrine.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 27 - }, - "methyprylon": { - "name": "methyprylon", - "properties": { - "summary": "Sedative of the pipeidinedone family. Was used for treating insomnia, yet is rarely used today due to substances with fewer side effects, such as benzodiazepines.", - "dose": "Light: 150-200mg Common: 200-300mg Strong: 300mg+", - "duration": "6-12 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "after-effects": "1-16 hours.", - "aliases": [ - "noludar" - ] - }, - "pretty_name": "Methyprylon", - "aliases": [ - "noludar" - ], - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "150-200mg", - "Common": "200-300mg", - "Strong": "300mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "id": 28 - }, - "bupropion": { - "name": "bupropion", - "properties": { - "summary": "A frequently prescribed atypical antidepressant. Occasionally prescribed as an aid to smoking cessation. May lower seizure threshold in predisposed individuals. Poorly understood mechanism of action, probably an NDRI. Avoid combination with other drugs.", - "duration": "Parent: 11-21 hours | Metabolites: 20-37 hours", - "general-effects": "Mild - moderate increase in motor activity and agitation/excitement", - "adverse-effects": "Agitation, dry mouth, insomnia, headache/migraine, nausea/vomiting, constipation, tremor, dizziness, excessive sweating, blurred vision, tachycardia, confusion, rash, hostility, cardiac arrhythmia, and auditory disturbance", - "overdose-symptoms": "Seizure, hallucinations, loss of consciousness, sinus tachycardia, ECG changes, bradycardia, cardiac failure, cardiac arrest, and death", - "warning": "Bupropion lowers the seizure threshold and can induce seizures when excessive doses are used and/or when combined with CNS stimulants or other drugs that also lower the threshold, such as theophylline, steroids, some tricyclic antidepressants, and alcohol", - "chemistry": "IUPAC: (±)-2-(tert-Butylamino)-1-(3-chlorophenyl)propan-1-one | Formula: C13H18ClNO | Molecular Mass: 239.74 g/mol", - "pharmacology": "NDRI (Norepinephrine-Dopamine Reuptake Inhibitor); NDRA (Norepinephrine-Dopamine Releasing Agent); α3β2, α3β4, α4β2, and α7 nACh receptor antagonist", - "pharmacokinetics": "Protein Binding: 84% (bupropion), 77% [hydroxybupropion (active metabolite)], 42% [threohydrobupropion (active metabolite)] | Metabolism: hepatic, primarily CYP2B6-mediated hydroxylation; both bupropion and hydroxybupropion (active metabolite) are CYP2D6 inhibitors | Excretion: renal (87%; 0.5% unchanged) and faecal (10%)", - "legal": "Australia: Prescription Only (S4) | Canada: ℞-only | United Kingdom: POM | United States: ℞-only", - "categories": [ - "stimulant", - "habit-forming" - ], - "aliases": [ - "wellbutrin", - "zyban", - "amfebutamone" - ], - "onset": "15-90 minutes.", - "contradictions": "Seizure disorder, current or prior diagnosis of bulimia or anorexia nervosa, abrupt discontinuation of alcohol, benzodiazepines, barbiturates, and anti-epileptic drugs, and MAOIs,", - "after-effects": "1-6 hours." - }, - "pretty_name": "Bupropion", - "aliases": [ - "wellbutrin", - "zyban", - "amfebutamone" - ], - "categories": [ - "stimulant", - "habit-forming" - ], - "formatted_dose": { - "none": { - "NOTE": "Highly" - } - }, - "formatted_duration": { - "Parent": "11-21", - "Metabolites": "20-37", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Evaluation of a Potential Metabolism-Mediated Drug-Drug Interaction Between Atomoxetine and Bupropion in Healthy Volunteers. http://www.ncbi.nlm.nih.gov/pubmed/27518170" - ] - }, - "id": 29 - }, - "4-ho-mpt": { - "name": "4-ho-mpt", - "properties": { - "summary": "Psychedelic drug of the tryptamine class. Higher homologue of Psilocin, and is the 4-hydroxy analogue of N-Methyl-N-Propyltryptamine.", - "onset": "Oral: 30-60 minutes. | Vapourized: 1-2 minutes.", - "duration": "Oral: 3-6 hours. | Vapourized: 45-90 minutes.", - "dose": "Oral Light: 5-10mg Common: 10-15mg Strong: 15-25mg | Vapourized Light: 3-5mg Common: 5-10mg Strong: 10-15mg | Note: I couldn't find a report that taking this substance rectally produced any effects.", - "after-effects": "1-6 hours.", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "aliases": [ - "4hompt" - ] - }, - "pretty_name": "4-HO-MPT", - "aliases": [ - "4hompt" - ], - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-25mg" - }, - "Vapourized": { - "Light": "3-5mg", - "Common": "5-10mg", - "Strong": "10-15mg" - } - }, - "formatted_duration": { - "Oral": "3-6", - "Vapourized": "45-90", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60", - "Vapourized": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "dose_note": " Note: I couldn't find a report that taking this substance rectally produced any effects.", - "id": 30 - }, - "rolicyclidine": { - "name": "rolicyclidine", - "properties": { - "summary": "Rolicyclidine, also known as PCPy, is a dissociative with effects similar to PCP. While this dissociative anesthetic has hallucinogenic and sedative effects, it is said to be much less stimulating than PCP. In this sense it is more similar to opioids, or other central nervous system depressants.", - "dose": "Light: 2-4mg Common: 4-8mg Strong: 8mg+", - "onset": "Oral: 30-60 minutes | Nasal 30 minutes.", - "duration": "2-6 hours", - "avoid": "All CNS depressants.", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "pcpy" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Rolicyclidine", - "aliases": [ - "pcpy" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "2-4mg", - "Common": "4-8mg", - "Strong": "8mg+" - } - }, - "formatted_duration": { - "value": "2-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60", - "Nasal": "30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 31 - }, - "halothane": { - "name": "halothane", - "properties": { - "summary": "A powerful inhalant anaesthetic generally used in a medical setting to induce unconsciousness, as a supplement with ketamine or fentanyl.", - "categories": [ - "depressant", - "tentative" - ] - }, - "pretty_name": "Halothane", - "categories": [ - "depressant", - "tentative" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Halothane.shtml" - }, - "id": 32 - }, - "prl-8-53": { - "name": "prl-8-53", - "properties": { - "summary": "A nootropic research chemical first synthesized in the 70s. One study shows a drastic improvement in mid-term memory among users, but otherwise it is severely lacking in information surrounding it. It has no recreational potential.", - "onset": "Oral: Within 30 minutes. | Sublingual: Within 15 minutes. | Intranasally: Within 5 minutes.", - "duration": "Oral: 4-6 hours | Sublingual: 3-5 hours | Intranasally: 2-4 hours.", - "dose": "Threshold: 2-3mg Low: 3-5mg Common: 5-10mg Strong: 10-20mg+ | NOTE: start low and work your way up.", - "categories": [ - "research-chemical", - "nootropic", - "tentative" - ], - "aliases": [ - "prl853" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "PRL-8-53", - "aliases": [ - "prl853" - ], - "categories": [ - "research-chemical", - "nootropic", - "tentative" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "2-3mg", - "Low": "3-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "Oral": "4-6", - "Sublingual": "3-5", - "Intranasally": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "Within", - "Sublingual": "Within", - "Intranasally": "Within", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_PRL853.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: start low and work your way up.", - "id": 33 - }, - "oxymorphone": { - "name": "oxymorphone", - "properties": { - "summary": "A powerful semisynthetic opioid analgesic also known as opana. A derivative of morphine it is approximately ten times as potent. Has a low oral bioavailability, and as such it is usually insufflated or taken rectally.", - "onset": "Oral_IR: 20-40 minutes | Oral_ER: 60-90 minutes. | Insufflated: 1-5 minutes | Plugged: 15-30 minutes. | IV: 0-1 minutes", - "duration": "Oral_IR: 4-8 hours | Oral_ER: 6-14 hours | Insufflated 5-8 hours | Plugged: 4-7 hours | IV: 2-4 hours. | Note: Tolerance + contents in your stomach can cause this to be quite different.", - "dose": "Oral Low: 5-7.5mg Common: 10-20mg Heavy: 20mg+ | Insufflated Low: 2-4mg Common: 4-6mg Heavy: 6-10mg+", - "avoid": "All other CNS depressants.", - "warning": "NOTE: There has been reports of a rare blood disorder from Intravenous use of Oxymorphone ER. Take this into consideration before taking the drug this way.", - "aliases": [ - "opana", - "stopsigns" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "bioavailability": "Intranasal: 43%, Oral: 10-20%, Rectal: 10%", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Oxymorphone", - "aliases": [ - "opana", - "stopsigns" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Low": "5-7.5mg", - "Common": "10-20mg", - "Heavy": "20mg+" - }, - "Insufflated": { - "Low": "2-4mg", - "Common": "4-6mg", - "Heavy": "6-10mg+" - } - }, - "formatted_duration": { - "Oral_IR": "4-8", - "Oral_ER": "6-14", - "Insufflated": "5-8", - "Plugged": "4-7", - "IV": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral_IR": "20-40", - "Oral_ER": "60-90", - "Insufflated": "1-5", - "Plugged": "15-30", - "IV": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 34 - }, - "pce": { - "name": "pce", - "properties": { - "duration": "2-5 hours.", - "onset": "Insufflated 5-15 minutes.", - "dose": "Insufflated Light: 1-3mg Common: 3-7mg Strong: 7-15mg+", - "aliases": [ - "eticyclidine" - ], - "categories": [ - "dissociative", - "tentative", - "habit-forming" - ], - "summary": "Eticyclidine (PCE) is a Dissociative anesthetic that has hallucinogenic effects. Slightly more potent than Phencyclidine.", - "after-effects": "1-4 hours." - }, - "pretty_name": "PCE", - "aliases": [ - "eticyclidine" - ], - "categories": [ - "dissociative", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Insufflated": { - "Light": "1-3mg", - "Common": "3-7mg", - "Strong": "7-15mg+" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Insufflated", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 35 - }, - "4-aco-dmt": { - "name": "4-aco-dmt", - "properties": { - "dose": "Oral Light: 5-10mg Common: 10-25mg Heavy: 25-40mg", - "duration": "4-8 hours.", - "summary": "A prodrug for Psilocin with extremely similar effects as Mushrooms.", - "comeup": "Slow comeup, some users report it taking nearly 2 hours until first effects are felt.", - "effects": "4-aco-dmt is a psilocin analog, so effects are very similar to mushrooms. Some users report very little difference between 4-aco-dmt and mushrooms.", - "aliases": [ - "4acodmt", - "psilacetin", - "4-aco", - "4-acetoxy-dmt" - ], - "onset": "20-90 minutes. (dependant on form and stomach contents)", - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "4-AcO-DMT", - "aliases": [ - "4acodmt", - "psilacetin", - "4-aco", - "4-acetoxy-dmt" - ], - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-25mg", - "Heavy": "25-40mg" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "4-aco-dmt is a psilocin analog", - "so effects are very similar to mushrooms", - "Some users report very little difference between 4-aco-dmt and mushrooms", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4AcODMT.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Enhancement and suppression cycles": "https://psychonautwiki.org/wiki/Enhancement_and_suppression_cycles", - "Excessive yawning": "https://psychonautwiki.org/wiki/Excessive_yawning", - "Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/Exposure_to_inner_mechanics_of_consciousness", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Feelings of impending doom": "https://psychonautwiki.org/wiki/Feelings_of_impending_doom", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Feelings of predeterminism": "https://psychonautwiki.org/wiki/Feelings_of_predeterminism", - "Feelings of self-design": "https://psychonautwiki.org/wiki/Feelings_of_self-design", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Machinescapes": "https://psychonautwiki.org/wiki/Machinescapes", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Personal meaning enhancement": "https://psychonautwiki.org/wiki/Personal_meaning_enhancement", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Rejuvenation": "https://psychonautwiki.org/wiki/Rejuvenation", - "Runny nose": "https://psychonautwiki.org/wiki/Runny_nose", - "Salivation": "https://psychonautwiki.org/wiki/Salivation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 36 - }, - "flualprazolam": { - "name": "flualprazolam", - "properties": { - "summary": "Fluorinated alprazolam, that likely has a longer half-life and higher potency than its parent compound.", - "duration": "6-14 hours.", - "onset": "10-30 minutes.", - "avoid": "All other CNS depressants.", - "dose": "Oral Light: 0.125-0.25mg Common: 0.25-0.5mg Strong: 0.5-1mg Heavy: 1-2mg", - "categories": [ - "benzodiazepine", - "habit-forming", - "tentative", - "research-chemical" - ], - "after-effects": "1-36 hours." - }, - "pretty_name": "Flualprazolam", - "categories": [ - "benzodiazepine", - "habit-forming", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "0.125-0.25mg", - "Common": "0.25-0.5mg", - "Strong": "0.5-1mg", - "Heavy": "1-2mg" - } - }, - "formatted_duration": { - "value": "6-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-36", - "_unit": "hours" - }, - "id": 37 - }, - "flurazepam": { - "name": "flurazepam", - "properties": { - "summary": "Benzodiazepine with an extremely long half life, between 40 and 250 hours. Mainly used for general anxiety disorder. Sedating, hypnotic, anxiolytic. Potential for amnesia and reduced inhibitions in overdose.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "dose": "Light: 5-10mg Common: 15-30mg Strong: 30-60mg.", - "duration": "12-16 hours.", - "onset": "45-90 minutes.", - "avoid": "All other CNS depressants.", - "after-effects": "2-48 hours.", - "aliases": [ - "dalmane" - ], - "bioavailability": "Oral 83%", - "dose_to_diazepam": "Flurazepam - 15-30mg's ~=10mg Diazepam." - }, - "pretty_name": "Flurazepam", - "aliases": [ - "dalmane" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "15-30mg", - "Strong": "30-60mg." - } - }, - "formatted_duration": { - "value": "12-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "2-48", - "_unit": "hours" - }, - "id": 38 - }, - "2c-t-2": { - "name": "2c-t-2", - "properties": { - "summary": "An unusual psychedelic with similar effects to 2C-B and a slightly longer duration, but maligned because of some deaths in the 2000s. Also similar to 2c-t-7, but with a shorter duration. Potentially unsafe with stimulants and empathogens.", - "dose": "Oral Threshold: 5mg Light: 5-10mg Common: 10-20mg Strong: 20-25mg+", - "onset": "45-90 minutes.", - "duration": "5-8 hours.", - "avoid": "MAOI's as the dangers with 2C-T-7 could also fall into this substance as well (Serotonin Syndrome)", - "aliases": [ - "2ct2" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-6 hours.", - "test-kits": "Marquis: Fizzes Pale Orange. | Mecke: Orange > Purple. | Mandelin: Purple. | Froehde: Orange > Purple | Liebermann: Red or Purple. | Ehrlich: No colour change." - }, - "pretty_name": "2C-T-2", - "aliases": [ - "2ct2" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5mg", - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-25mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CT2.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal040.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Stomach cramps": "https://psychonautwiki.org/wiki/Stomach_cramps", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 39 - }, - "det": { - "name": "det", - "properties": { - "onset": "Vaporized: 1-5 minutes. | Oral: 30-90 minutes.", - "summary": "A surprisingly uncommon analogue of DMT with similar effects and reported oral activity without the aid of an MAOI.", - "aliases": [ - "diethyltryptamine" - ], - "duration": "2-4 hours.", - "after-effects": "1-6 hours.", - "dosage": "Vaporized (using a 100% success method) Light: 15-25mg's Common: 30-50mg's Strong: 50mg+ Orally Light: 20-40mg's Common: 50-80mg's Strong: 80mg+", - "dose": "Vapourized Light: 15-25mg Common: 30-50mg Strong: 50mg+ | Oral Light: 20-40mg Common: 50-80mg Strong: 80mg+", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "DET", - "aliases": [ - "diethyltryptamine" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Vapourized": { - "Light": "15-25mg", - "Common": "30-50mg", - "Strong": "50mg+" - }, - "Oral": { - "Light": "20-40mg", - "Common": "50-80mg", - "Strong": "80mg+" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Vaporized": "1-5", - "Oral": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DET.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal03.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 40 - }, - "nimetazepam": { - "name": "nimetazepam", - "properties": { - "summary": "A pharmaceutical benzodiazepine with hypnotic and sedative effects. Rarely seen in the West but reportedly very frequently abused in Malaysia.", - "onset": "15-30 minutes.", - "duration": "5-8 hours", - "after-effects": "12-24 hours", - "avoid": "All other CNS depressants.", - "dose": "Oral Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg+", - "aliases": [ - "erimin" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic." - }, - "pretty_name": "Nimetazepam", - "aliases": [ - "erimin" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "12-24", - "_unit": "hours" - }, - "id": 41 - }, - "ronlax": { - "name": "ronlax", - "properties": { - "summary": "A benzodiazepine derivative that posses the standard benzodiazepine effects. It has a very long half life (51-103 hours) it metabolizes into an active compound. (Descarboxyloflazepate) Is sold in Mexico.", - "aliases": [ - "ethyl-loflazepate", - "meilax", - "victan" - ], - "onset": "45-90 minutes.", - "duration": "8-16 hours.", - "after-effects": "1-24 hours.", - "dose": "Oral Light: 0.5-1mg Common: 1-2mg Strong: 2-4mg.", - "avoid": "All CNS depressants. Also if using the antidepressant Fluvoxamine may potentiate the adverse effects.", - "categories": [ - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Ronlax", - "aliases": [ - "ethyl-loflazepate", - "meilax", - "victan" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg." - } - }, - "formatted_duration": { - "value": "8-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 42 - }, - "a-pihp": { - "name": "a-pihp", - "properties": { - "dose": "Oral Threshold: 3-5mg Light: 5-15mg Common: 15-30mg Strong: 30-50mg | Insufflated Threshold: 1-3mg Light: 3-10mg Common: 10-25mg Strong: 25-40mg | Vapourized Threshold: 1-2mg Light: 2-10mg Common: 10-20mg Strong: 20-30mg.", - "summary": "Quite new Pyrrolidine based stimulant of the cathinone class. Not very many reports. Probably has a very fast tolerance raise, and lack of effects over time.", - "onset": "Oral: 30-60 minutes. | Insufflated: 1-2 minutes. | Vapourized: 1 minute.", - "duration": "Oral: 2-5 hours | Insufflated: 2-4 hours. | Vapourized: 1-3 hours.", - "after-effects": "6-12 hours.", - "categories": [ - "stimulant", - "empathogen", - "habit-forming", - "research-chemical", - "tentative" - ], - "avoid": "Other stimulants, pretty much everything that can raise your blood pressure.", - "aliases": [ - "pihp" - ] - }, - "pretty_name": "A-PIHP", - "aliases": [ - "pihp" - ], - "categories": [ - "stimulant", - "empathogen", - "habit-forming", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3-5mg", - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg" - }, - "Insufflated": { - "Threshold": "1-3mg", - "Light": "3-10mg", - "Common": "10-25mg", - "Strong": "25-40mg" - }, - "Vapourized": { - "Threshold": "1-2mg", - "Light": "2-10mg", - "Common": "10-20mg", - "Strong": "20-30mg." - } - }, - "formatted_duration": { - "Oral": "2-5", - "Insufflated": "2-4", - "Vapourized": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60", - "Insufflated": "1-2", - "Vapourized": "1", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "6-12", - "_unit": "hours" - }, - "id": 43 - }, - "melatonin": { - "name": "melatonin", - "properties": { - "summary": "A naturally occurring hormone produced in the body, which promotes sleep at certain times in the day based on the circadian rhythm. It is also commonly available as a drug to treat insomnia and promote a proper sleep cycle. It can be used to promote sleepfulness at the tail-end of drug experiences, though it is not particularly hypnotic.", - "onset": "Within an hour.", - "duration": "6-8 hours.", - "dose": "Common: .3-1mg", - "categories": [ - "nootropic", - "common", - "supplement" - ] - }, - "pretty_name": "Melatonin", - "categories": [ - "nootropic", - "common", - "supplement" - ], - "formatted_dose": { - "Oral": { - "Common": ".3-1mg" - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Within" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Melatonin.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal35.shtml" - }, - "pweffects": { - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation" - }, - "sources": { - "_general": [ - "Intranasal absorption of melatonin in vivo bioavailability study. - http://www.ncbi.nlm.nih.gov/pubmed/10332069", - "Solubility and stability of melatonin in propylene glycol and 2-hydroxypropyl-beta-cyclodextrin vehicles. - http://www.ncbi.nlm.nih.gov/pubmed/18982260", - "Melatonin, a potential therapeutic agent for smooth muscle-related pathological conditions and aging. - http://www.ncbi.nlm.nih.gov/pubmed/20939818", - "Anxiolytic-like effects of a new 1-N substituted analog of melatonin in pinealectomized rats. - http://www.ncbi.nlm.nih.gov/pubmed/24495777", - "Sleep-inducing effects of low doses of melatonin ingested in the evening. - http://www.ncbi.nlm.nih.gov/pubmed/7768078", - "Anxiolytic activity of melatonin in mice: involvement of benzodiazepine receptors. - http://www.ncbi.nlm.nih.gov/pubmed/7905658" - ], - "dose": [ - "http://news.mit.edu/2001/melatonin-1017" - ] - }, - "id": 44 - }, - "ketazolam": { - "name": "ketazolam", - "properties": { - "summary": "Benzodiazepine derivative that has most of the common benzodiazepine effects. Has been seen to have similar effectiveness when compared to Diazepam, with milder side-effects. Is marketed in few countries.", - "avoid": "All other CNS depressants.", - "dose": "Light: 5-15mg Common: 15-30mg Strong: 30-60mg+", - "onset": "30-90 minutes.", - "duration": "8-12 hours.", - "after-effects": "2-12 hours.", - "categories": [ - "depressant", - "habit-forming" - ], - "dose_to_diazepam": "Ketazolam - 15-30mg's ~=10mg Diazepam." - }, - "pretty_name": "Ketazolam", - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-60mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 45 - }, - "sonata": { - "name": "sonata", - "properties": { - "dose": "Oral Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg.", - "duration": "3-6 hours.", - "onset": "10-30 minutes.", - "summary": "Sedative-Hypnotic of the nonbenzodiazepine from the Pyrazolopyramide class. It is used mostly for short term insomnia.", - "avoid": "All other CNS depressants.", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "aliases": [ - "zaleplon" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Sonata", - "aliases": [ - "zaleplon" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 46 - }, - "4-ho-ept": { - "name": "4-ho-ept", - "properties": { - "summary": "The 4-Hydroxy version of EPT. Slightly more potent than the prior.", - "categories": [ - "psychedelic", - "tentative" - ], - "dose": "Light: 10-20mg Common: 20-30mg Strong: 30-50mg+", - "onset": "30-45 minutes.", - "duration": "4-8 hours.", - "after-effects": "1-12 hours." - }, - "pretty_name": "4-HO-EPT", - "categories": [ - "psychedelic", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-30mg", - "Strong": "30-50mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 47 - }, - "citalopram": { - "name": "citalopram", - "properties": { - "summary": "Citalopram is an SSRI that is used to treat depression. It does not lead to a high and causes a wide range of negative psychological and physical effects when people attempt to abuse it and can lead to serotonin syndrome and cause suicidal ideation. Those with bipolar disorder tend to go into a mixed state or manic states when trying SSRI's.", - "dose": "20-40mg Once a day.", - "categories": [ - "common", - "ssri" - ], - "aliases": [ - "celexa", - "cipramil" - ] - }, - "pretty_name": "Citalopram", - "aliases": [ - "celexa", - "cipramil" - ], - "categories": [ - "common", - "ssri" - ], - "formatted_dose": { - "20-40mg": {} - }, - "id": 48 - }, - "alpha-php": { - "name": "alpha-php", - "properties": { - "duration": "2-8 hours dependant on ROA.", - "dose": "Light: 5-10mg Common: 10-20mg Strong: 20-40mg+", - "summary": "A powerful stimulant cathinone, analogue of alpha-PVP and related to pyrovalerone. Said to have high addictive potential, compulsive redosing and relatively short duration. Often insufflated or vapourised.", - "onset": "1-10 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "pv-7", - "a-php", - "aphp", - "α-php", - "αphp" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "after-effects": "1-48 hours." - }, - "pretty_name": "α-PHP", - "aliases": [ - "pv-7", - "a-php", - "aphp", - "α-php", - "αphp" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg+" - } - }, - "formatted_duration": { - "value": "2-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_alphaPHP.shtml" - }, - "formatted_aftereffects": { - "value": "1-48", - "_unit": "hours" - }, - "id": 49 - }, - "bentazepam": { - "name": "bentazepam", - "properties": { - "2-6": "hours.", - "summary": "Thienodiazepine that is an effective anxiolyric. Liver damage among other nasty things have been reported.", - "aliases": [ - "thiadipone", - "tiadipona" - ], - "avoid": "All other CNS depressants.", - "onset": "15-45 minutes.", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "dose": "Light: 15-30mg Common: 30-50mg Strong: 50-75mg+ | NOTE: Liver damage has been reported a fair amount, so get your livers checked out regularly if using this substance over a prolonged amount of time.", - "duration": "3-6 hours.", - "after-effects": "1-8 hours." - }, - "pretty_name": "Bentazepam", - "aliases": [ - "thiadipone", - "tiadipona" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Light:": { - "Light": "15-30mg", - "Common": "30-50mg", - "Strong": "50-75mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " NOTE: Liver damage has been reported a fair amount, so get your livers checked out regularly if using this substance over a prolonged amount of time.", - "sources": { - "_general": [ - "Bentazepam versus Clorazepate in the treatment of anxiety disorders. http://www.sciencedirect.com/science/article/pii/S0011393X05804357" - ] - }, - "id": 50 - }, - "2c-d": { - "name": "2c-d", - "properties": { - "dose": "Oral Threshold: 3-4mg Light: 5-15mg Common: 20-50mg Strong: 50-100mg", - "duration": "3-5 hours", - "onset": "15-45 minutes", - "effects": "comparable to 2C-B, mental and physical stimulation, mood lift, euphoria, cognitive enhancement, increased mental clarity and interest, feelings of empathy, enhanced tactile sensation, sensory enhancement, brightened colors, sociability, introspection, giggling, pupil dilation, increased heart rate, changes in perception of time, stomach discomfort, headache, dizziness, anxiety", - "summary": "A fairly generic psychedelic famed for being usable as \"psychedelic tofu\". Little character of its own but pleasant in combinations.", - "aliases": [ - "2cd", - "2c-m", - "2cm" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "after-effects": "1-8 hours.", - "test-kits": "Marquis: Yellow > Brown. | Mecke: Green > Brown. | Mandelin: Green/Yellow. | Simon's Brown > Red. | Ehrlich: No colour change." - }, - "pretty_name": "2C-D", - "aliases": [ - "2cd", - "2c-m", - "2cm" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3-4mg", - "Light": "5-15mg", - "Common": "20-50mg", - "Strong": "50-100mg" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "comparable to 2C-B", - "mental and physical stimulation", - "mood lift", - "euphoria", - "cognitive enhancement", - "increased mental clarity and interest", - "feelings of empathy", - "enhanced tactile sensation", - "sensory enhancement", - "brightened colors", - "sociability", - "introspection", - "giggling", - "pupil dilation", - "increased heart rate", - "changes in perception of time", - "stomach discomfort", - "headache", - "dizziness", - "anxiety" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CD.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal023.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 51 - }, - "cannabis": { - "name": "cannabis", - "properties": { - "summary": "A common and widely used psychoactive plant, which is beginning to enjoy legal status for medical and even recreational use in some parts of the world. Usually smoked or eaten, primary effects are relaxation and an affinity towards food - a state described as being 'stoned.'", - "detection": "Single Use: blood 1-3 days, saliva 12-24 hrs, urine 1-3 days, hair 0 to 90 days. Regular use: blood 1-2 weeks, saliva 15-50 days, urine 15-50 days, hair 0 to 90 days. Oral single use: blood: 2-7 days", - "duration": "Smoked: 1-4 hours | Oral: 4-10 hours", - "onset": "Smoked: 1-10 minutes | Oral: 30-120 minutes", - "after-effects": "Smoked: 2-24 hours | Oral: 6-24 hours", - "aliases": [ - "weed", - "thc", - "marijuana", - "dagga", - "hash" - ], - "categories": [ - "depressant", - "stimulant", - "psychedelic", - "habit-forming", - "common" - ], - "dose": "Smoked Light: 33mg Common: 66mg Strong: 100mg. Oral Light: 10-20mg Common: 20-60mg Strong: 60-100mg+", - "effects": "Sedation, Appetite enhancement, Muscle relaxation, Muscle spasms, Nausea, Pain relief, Vasodilation, Creativity Enhancement, Anxiety suppression, Anxiety, Dream suppression, Emotion enhancement, Mindfulness, Paranoia, Sleepiness." - }, - "pretty_name": "Cannabis", - "aliases": [ - "weed", - "thc", - "marijuana", - "dagga", - "hash" - ], - "categories": [ - "depressant", - "stimulant", - "psychedelic", - "habit-forming", - "common" - ], - "formatted_dose": { - "Smoked": { - "Light": "10-20mg", - "Common": "20-60mg", - "Strong": "60-100mg+" - } - }, - "formatted_duration": { - "Smoked": "1-4", - "Oral": "4-10", - "_unit": "hours" - }, - "formatted_onset": { - "Smoked": "1-10", - "Oral": "30-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Sedation", - "Appetite enhancement", - "Muscle relaxation", - "Muscle spasms", - "Nausea", - "Pain relief", - "Vasodilation", - "Creativity Enhancement", - "Anxiety suppression", - "Anxiety", - "Dream suppression", - "Emotion enhancement", - "Mindfulness", - "Paranoia", - "Sleepiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Cannabis.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Appetite enhancement": "https://psychonautwiki.org/wiki/Appetite_enhancement", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Brightness alteration": "https://psychonautwiki.org/wiki/Brightness_alteration", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Dream suppression": "https://psychonautwiki.org/wiki/Dream_suppression", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Feelings of impending doom": "https://psychonautwiki.org/wiki/Feelings_of_impending_doom", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Laughter": "https://psychonautwiki.org/wiki/Laughter", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Nausea suppression": "https://psychonautwiki.org/wiki/Nausea_suppression", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Paranoia": "https://psychonautwiki.org/wiki/Paranoia", - "Perception of increased weight": "https://psychonautwiki.org/wiki/Perception_of_increased_weight", - "Personal meaning enhancement": "https://psychonautwiki.org/wiki/Personal_meaning_enhancement", - "Psychosis": "https://psychonautwiki.org/wiki/Psychosis", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Seizure suppression": "https://psychonautwiki.org/wiki/Seizure_suppression", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Suggestibility enhancement": "https://psychonautwiki.org/wiki/Suggestibility_enhancement", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Vasodilation": "https://psychonautwiki.org/wiki/Vasodilation" - }, - "formatted_aftereffects": { - "Smoked": "2-24", - "Oral": "6-24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Cannabis use and risk of lung cancer: a case-control study. - http://www.ncbi.nlm.nih.gov/pubmed/18238947", - "Cannabis smoking and risk of lung cancer in men: a pooled analysis of three studies in Maghreb. - http://www.ncbi.nlm.nih.gov/pubmed/19057263", - "Cannabis induces a clinical response in patients with Crohn's disease: a prospective placebo-controlled study. - http://www.ncbi.nlm.nih.gov/pubmed/23648372", - "Effects of cannabis on the adolescent brain. - http://www.ncbi.nlm.nih.gov/pubmed/23829363", - "Is cannabis neurotoxic for the healthy brain? A meta-analytical review of structural brain alterations in non-psychotic users. - http://www.ncbi.nlm.nih.gov/pubmed/24118193", - "A controlled family study of cannabis users with and without psychosis. - http://www.ncbi.nlm.nih.gov/pubmed/24309013", - "How cannabis causes paranoia: using the intravenous administration of ∆9-tetrahydrocannabinol (THC) to identify key cognitive mechanisms leading to... - http://www.ncbi.nlm.nih.gov/pubmed/25031222", - "The impact of marijuana use on glucose, insulin, and insulin resistance among US adults. - https://www.ncbi.nlm.nih.gov/pubmed/23684393", - "Marijuana and lung diseases. - https://www.ncbi.nlm.nih.gov/pubmed/24384575", - "Neuroprotective antioxidants from marijuana. - http://www.ncbi.nlm.nih.gov/pubmed/10863546", - "Decreased depression in marijuana users. - http://www.ncbi.nlm.nih.gov/pubmed/15964704", - "Self-reported anal sex practice and sexual risk-taking after marijuana use among a sample of Georgia inmates. - http://www.ncbi.nlm.nih.gov/pubmed/16820076", - "Effects of marijuana extract and tetrahydrocannabinol on electroencephalographic sleep patterns. - http://www.ncbi.nlm.nih.gov/pubmed/178475", - "Association of marijuana use and the incidence of testicular germ cell tumors. - http://www.ncbi.nlm.nih.gov/pubmed/19204904", - "The effects of combinations of intranasal cocaine, smoked marijuana, and task performance on heart rate and blood pressure. - http://www.ncbi.nlm.nih.gov/pubmed/2162543", - "Ischemic stroke after use of the synthetic marijuana \"spice\". - http://www.ncbi.nlm.nih.gov/pubmed/24212384", - "Marijuana's effects on human cognitive functions, psychomotor functions, and personality. - http://www.ncbi.nlm.nih.gov/pubmed/3009708", - "Effects of marijuana on human reaction time and motor control. - http://www.ncbi.nlm.nih.gov/pubmed/600655", - "Effects of marijuana on testosterone in male subjects. - http://www.ncbi.nlm.nih.gov/pubmed/6316036", - "Detection times of marijuana metabolites in urine by immunoassay and GC-MS. - http://www.ncbi.nlm.nih.gov/pubmed/8926739", - "Medical/therapeutic value of cannabis literature review - http://bjp.rcpsych.org/content/178/2/107.short" - ] - }, - "combos": { - "mushrooms": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "lsd": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "dmt": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "mescaline": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "dox": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "nbomes": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "2c-x": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "2c-t-x": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "amt": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Small amounts can reduce nausea with aMT but take care." - }, - "5-meo-xxt": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & Synergy" - }, - "pcp": { - "status": "Low Risk & Synergy" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "mdma": { - "status": "Low Risk & Synergy", - "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible." - }, - "cocaine": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "caffeine": { - "status": "Low Risk & No Synergy" - }, - "alcohol": { - "status": "Low Risk & Synergy", - "note": "In excess, this combination can cause nausea." - }, - "ghb/gbl": { - "status": "Low Risk & Synergy" - }, - "opioids": { - "status": "Low Risk & Synergy" - }, - "tramadol": { - "status": "Low Risk & Synergy" - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Low Risk & Synergy" - }, - "ssris": { - "status": "Low Risk & No Synergy" - } - }, - "id": 52 - }, - "salvia": { - "name": "salvia", - "properties": { - "summary": "A plant which, when smoked, causes short but very intense psychedelic experiences. It is considered physically safe, though users of high dosages often experience bizarre other-worldly scenarios which may be confusing or terrifying.", - "duration": "Sublingual: 30-60 minutes | Smoked: 5-30 minutes", - "onset": "Sublingual: 10-20 minutes | Smoked: 0-2 minutes", - "after-effects": "15-20 minutes", - "effects": "radical shift in perspective and perception, creative dreamlike experience, increase in sensual and aesthetic appreciation, introspective insight, powerful closed/open eye visuals, general change in consciousness, dissociation, panic, perspiration, inability to control muscles", - "categories": [ - "dissociative", - "deliriant", - "depressant", - "common" - ] - }, - "pretty_name": "Salvia", - "categories": [ - "dissociative", - "deliriant", - "depressant", - "common" - ], - "formatted_duration": { - "Sublingual": "30-60", - "Smoked": "5-30", - "_unit": "minutes" - }, - "formatted_onset": { - "Sublingual": "10-20", - "Smoked": "0-2", - "_unit": "minutes" - }, - "formatted_effects": [ - "radical shift in perspective and perception", - "creative dreamlike experience", - "increase in sensual and aesthetic appreciation", - "introspective insight", - "powerful closed/open eye visuals", - "general change in consciousness", - "dissociation", - "panic", - "perspiration", - "inability to control muscles" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Changes in felt bodily form": "https://psychonautwiki.org/wiki/Changes_in_felt_bodily_form", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Cognitive dysphoria": "https://psychonautwiki.org/wiki/Cognitive_dysphoria", - "Depth perception distortions": "https://psychonautwiki.org/wiki/Depth_perception_distortions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Feelings of impending doom": "https://psychonautwiki.org/wiki/Feelings_of_impending_doom", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Laughter": "https://psychonautwiki.org/wiki/Laughter", - "Machinescapes": "https://psychonautwiki.org/wiki/Machinescapes", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Visual disconnection#Structures": "https://psychonautwiki.org/wiki/Visual_disconnection#Structures" - }, - "formatted_aftereffects": { - "value": "15-20", - "_unit": "minutes" - }, - "id": 53 - }, - "trazodone": { - "name": "trazodone", - "properties": { - "onset": "20-40 minutes.", - "duration": "6-10 hours.", - "summary": "A novel antidepressant of the SARI class, a serotonin antagonist and reuptake inhibitor. Often used to treat depression and anxiety. It has anxiolytic and hypnotic effects.", - "categories": [ - "depressant" - ], - "aliases": [], - "dose": "Light: 25-50mg Common: 50-100mg Strong: 100-150 | Note: Please do not take this drug unless prescribed." - }, - "pretty_name": "Trazodone", - "aliases": [], - "categories": [ - "depressant" - ], - "formatted_dose": { - "Light:": { - "Light": "25-50mg", - "Common": "50-100mg", - "Strong": "100-150" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "dose_note": " Note: Please do not take this drug unless prescribed.", - "id": 54 - }, - "camazepam": { - "name": "camazepam", - "properties": { - "summary": "A benzodiazepine drug that is stronger in terms of anxiety relief than it is in terms of how hypnotic it is. It is a metabolite of diazepam and has limited anticonvulsant properties.", - "dose": "Light: 10-20mg Moderate: 20-40mg Heavy: 40+ mg", - "aliases": [ - "albego", - "limpidon", - "paxor" - ], - "duration": "8-12 hours. Dose and tolerance dependent.", - "categories": [ - "benzodiazepine", - "habit-forming", - "tentative", - "depressant" - ], - "onset": "45-90 minutes.", - "avoid": "Avoid all other CNS depressants.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Camazepam", - "aliases": [ - "albego", - "limpidon", - "paxor" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Moderate": "20-40mg", - "Heavy": "40+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 55 - }, - "4-aco-mipt": { - "name": "4-aco-mipt", - "properties": { - "summary": "A quite potent tryptamine that has be related to having \"shroom-like\" visuals. Yet without much bodyload. Very hydroscopic. Seems to be quite safe in dosing. Similar to the likes of 2C-B.", - "duration": "Oral: 4-9 hours. | Duration: 1-2 hours.", - "aliases": [ - "mipracetin", - "4acomipt" - ], - "onset": "Oral: 15-45 minutes. | Vapourized: 1-2 minutes.", - "dose": "Oral Light: 5-10mg Common: 10-20mg Strong: 20-40mg. | Vapourized Light: 2-5mg Common: 5-10mg Strong: 10-15 mg.", - "categories": [ - "tentative", - "psychedelic", - "empathogen", - "research-chemical" - ], - "1-6": "hours." - }, - "pretty_name": "4-AcO-MiPT", - "aliases": [ - "mipracetin", - "4acomipt" - ], - "categories": [ - "tentative", - "psychedelic", - "empathogen", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg." - }, - "Vapourized": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10-15" - } - }, - "formatted_duration": { - "Oral": "4-9", - "Duration": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Vapourized": "1-2", - "_unit": "minutes" - }, - "id": 56 - }, - "doip": { - "name": "doip", - "properties": { - "summary": "A rare psychedelic ampthetamine of the same class as the likes of DOM. Is a quite powerful and potent psychedelic that has very strong amphetamine effects. Not for the faint of heart.", - "onset": "45-120 minutes.", - "duration": "18-30 hours.", - "dose": "Threshold: 800ug Light: 800-1500ug Common: 1.5-3mg Strong: 3mg+ || Note: This is based on personal experience as no trip reports have surfaced in the three years it's been on the market, so take with caution.", - "after-effects": "1-48 hours.", - "avoid": "Double dosing as it has a fairly long onset. Also any stimulant that's stronger than caffeine, and even then it can get quite uncomfortable.", - "categories": [ - "tentative", - "psychedelic", - "stimulant", - "research-chemical" - ] - }, - "pretty_name": "DOIP", - "categories": [ - "tentative", - "psychedelic", - "stimulant", - "research-chemical" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "800ug", - "Light": "800-1500ug", - "Common": "1.5-3mg", - "Strong": "3mg+" - }, - "": {} - }, - "formatted_duration": { - "value": "18-30", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-48", - "_unit": "hours" - }, - "dose_note": " Note: This is based on personal experience as no trip reports have surfaced in the three years it's been on the market, so take with caution.", - "id": 57 - }, - "escitalopram": { - "name": "escitalopram", - "properties": { - "categories": [ - "ssri" - ], - "aliases": [ - "lexapro", - "cipralex" - ] - }, - "pretty_name": "Escitalopram", - "aliases": [ - "lexapro", - "cipralex" - ], - "categories": [ - "ssri" - ], - "id": 58 - }, - "tma-6": { - "name": "tma-6", - "properties": { - "summary": "A rarely seen Psychedelic Amphetamine and Mescaline analogue. First synthesised by Alexander Shulgin, who descrived it as \"one of the most rewarding and pleasurable of the methoxylated amphetamines.\"", - "dose": "Threshold: 15-20mg Light: 20-30mg Common: 30-40mg Heavy: 40-50mg+", - "duration": "10-18 hours", - "onset": ">60 minutes.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "TMA-6", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "15-20mg", - "Light": "20-30mg", - "Common": "30-40mg", - "Heavy": "40-50mg+" - } - }, - "formatted_duration": { - "value": "10-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_TMA6.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal162.shtml" - }, - "formatted_aftereffects": { - "value": "Possibility", - "_unit": "hours" - }, - "id": 59 - }, - "2-fdck": { - "name": "2-fdck", - "properties": { - "summary": "Dissociative anesthetic of the arylcyclohexylamine class. Seemingly on par with ketamine in dosage. Longer onset than the prior.", - "dose": "Insufflated Light: 20-50mg Common: 50-100mg Strong: 100-175mg+", - "onset": "20-40 minutes.", - "duration": "1-3 hours.", - "categories": [ - "tentative", - "dissociative", - "habit-forming" - ], - "aliases": [ - "2f-ketamine", - "2f-ket", - "2-fluorodeschloroketamine", - "2-fl-2'-oxo-pcm", - "2f-dck", - "2fket", - "2fdck" - ], - "after-effects": "1-3 hours." - }, - "pretty_name": "2-FDCK", - "aliases": [ - "2f-ketamine", - "2f-ket", - "2-fluorodeschloroketamine", - "2-fl-2'-oxo-pcm", - "2f-dck", - "2fket", - "2fdck" - ], - "categories": [ - "tentative", - "dissociative", - "habit-forming" - ], - "formatted_dose": { - "Insufflated": { - "Light": "20-50mg", - "Common": "50-100mg", - "Strong": "100-175mg+" - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-3", - "_unit": "hours" - }, - "id": 60 - }, - "doet": { - "name": "doet", - "properties": { - "summary": "A potent and long acting psychedelic stimulant and substituted amphetamine, similar in effects to other DOx compounds. First synthesised by Alexander Shulgin.", - "duration": "12-30 hours (Dependant on dose)", - "dose": "Oral Threshold: 1mg Light: 2-4mg Common: 4-6mg Strong: 6-10mg | NOTE: These doses are tentative and may need further research.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "aliases": [ - "doe" - ], - "after-effects": "12-72 hours", - "onset": "1-3 hours.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "DOET", - "aliases": [ - "doe" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "1mg", - "Light": "2-4mg", - "Common": "4-6mg", - "Strong": "6-10mg" - } - }, - "formatted_duration": { - "value": "12-30", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DOET.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal066.shtml" - }, - "formatted_aftereffects": { - "value": "12-72", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 61 - }, - "tramadol": { - "name": "tramadol", - "properties": { - "dose": "Oral Light: 50-100mg Common: 100-250mg Heavy: 250-400mg | NOTE: Tramadol has a ceiling dose, where recreational effects are not increased. Risk of seizure at doses over 300mg. Tramadol decreases the seizure threshold, use extreme caution. Dosing insufflated is ineffective.", - "duration": "5-7 hours", - "effects": "euphoria, elevated mood, overall feeling of contentedness, itching, drowsiness, vomiting, urinary retention, nausea, constipation, risk of seizure above 300mg", - "onset": "1 hour first effects, reaching peak blood concentration at 4 hours.", - "avoid": "benzos, alcohol, and other opiates", - "summary": "A synthetic opioid analgesic, tramadol is used to treat moderate pain and can be considered a medium-strength opioid. Tramadol also has the unusual effect of being a serotonin releasing agent and a serotonin reuptake inhibitor, and as a consequence should not be taken in excess due to the risk of serotonin syndrome. Risk of seizures above 300mg doses.", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "bioavailability": "Oral 68-72% | Rectal 77%", - "aliases": [ - "tram" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Tramadol", - "aliases": [ - "tram" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-250mg", - "Heavy": "250-400mg" - } - }, - "formatted_duration": { - "value": "5-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1", - "_unit": "hours" - }, - "formatted_effects": [ - "euphoria", - "elevated mood", - "overall feeling of contentedness", - "itching", - "drowsiness", - "vomiting", - "urinary retention", - "nausea", - "constipation", - "risk of seizure above 300mg" - ], - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Tramadol has a ceiling dose, where recreational effects are not increased. Risk of seizure at doses over 300mg. Tramadol decreases the seizure threshold, use extreme caution. Dosing insufflated is ineffective.", - "sources": { - "_general": [ - "High-concentration tramadol-induced vasodilation in rabbit aorta is mediated by both endothelium-dependent and -independent mechanisms - http://www.ncbi.nlm.nih.gov/pubmed/12740170", - "Supra-additive effects of tramadol and acetaminophen in a human pain model - http://www.ncbi.nlm.nih.gov/pubmed/17709207", - "Opioid and nonopioid components independently contribute to the mechanism of action of tramadol making it 'atypical' - http://jpet.aspetjournals.org/content/260/1/275.short" - ] - }, - "combos": { - "mushrooms": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures." - }, - "lsd": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures." - }, - "dmt": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures." - }, - "mescaline": { - "status": "Unsafe", - "note": "This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures." - }, - "dox": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures." - }, - "nbomes": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and NBOMes have also shown a tendency to cause severe seizures" - }, - "2c-x": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics raise the risk of seizures." - }, - "2c-t-x": { - "status": "Unsafe" - }, - "amt": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Unsafe" - }, - "cannabis": { - "status": "Low Risk & Synergy" - }, - "ketamine": { - "status": "Dangerous" - }, - "mxe": { - "status": "Dangerous" - }, - "dxm": { - "status": "Dangerous" - }, - "pcp": { - "status": "Dangerous" - }, - "nitrous": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely." - }, - "amphetamines": { - "status": "Dangerous", - "note": "Tramadol and stimulants both increase the risk of seizures." - }, - "mdma": { - "status": "Dangerous", - "note": "Tramadol and stimulants both increase the risk of seizures." - }, - "cocaine": { - "status": "Dangerous", - "note": "Tramadol and stimulants both increase the risk of seizures." - }, - "caffeine": { - "status": "Low Risk & No Synergy" - }, - "alcohol": { - "status": "Dangerous", - "note": "Heavy CNS depressants, risk of seizures. Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely." - }, - "ghb/gbl": { - "status": "Dangerous", - "note": "The sedative effects of this combination can lead to dangerous respiratory depression." - }, - "opioids": { - "status": "Dangerous", - "note": "Concomitant use of tramadol increases the seizure risk in patients taking other opioids. These agents are often individually epileptogenic and may have additive effects on seizure threshold during coadministration. Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present" - }, - "benzodiazepines": { - "status": "Dangerous", - "note": "Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present. Vomit aspiration a risk when passed out, lay down in recovery position if ingested." - }, - "benzos": { - "status": "Dangerous", - "note": "Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present. Vomit aspiration a risk when passed out, lay down in recovery position if ingested." - }, - "maois": { - "status": "Dangerous" - }, - "ssris": { - "status": "Dangerous" - } - }, - "id": 62 - }, - "2-fea": { - "name": "2-fea", - "properties": { - "summary": "Stimulant closely related to 2-FMA. Presumably slightly less potent than the prior. Toxicology and the likes are pretty much completely unknown. Tread with caution.", - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ], - "aliases": [ - "2-fluoroethylamphetamine" - ] - }, - "pretty_name": "2-FEA", - "aliases": [ - "2-fluoroethylamphetamine" - ], - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ], - "id": 63 - }, - "diethyl-ether": { - "name": "diethyl-ether", - "properties": { - "onset": "Rapid", - "duration": "Short.", - "summary": "An industrial solvent which is sometimes used recreationally as a dissociative anaesthetic, with a short length of action. Effects are similar to alcohol. Leaves one's breath tasting and smelling strongly of ether for much longer than the experience lasts.", - "avoid": "Avoid CNS depressants and smoking.", - "obtain": "Air.", - "aliases": [ - "ether" - ], - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "after-effects": "1-6 hours | NOTE: The smell will linger for days afterwards." - }, - "pretty_name": "Diethyl ether", - "aliases": [ - "ether" - ], - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "formatted_duration": { - "value": "Short." - }, - "formatted_onset": { - "value": "Rapid" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ether.shtml" - }, - "formatted_aftereffects": { - "6": "hours", - "_unit": "hours" - }, - "id": 64 - }, - "cyclopropylmescaline": { - "name": "cyclopropylmescaline", - "properties": { - "duration": "12-18 hours", - "onset": "10-30 minutes", - "summary": "Cyclopropylmescaline, AKA CPM, is a psychedelic/hallucinogenic that was produced by Alexander Shulgin. It causes visual and auditory hallucinations and lasts quite a long time. Little is known about it so caution must be used when trying out this substance.", - "aliases": [ - "cpm", - "4-cyclopropylmethoxy-3" - ], - "dose": "Light: 50-60mg Common: 60-70mg: Strong: 70-80mg", - "warning": "Caution: not much is known about how CPM affects the body, be cautious with doses and how you use it.", - "after-effects": "6-8 hours.", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "Cyclopropylmescaline", - "aliases": [ - "cpm", - "4-cyclopropylmethoxy-3" - ], - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "50-60mg", - "Common": "60-70mg", - "Strong": "70-80mg" - } - }, - "formatted_duration": { - "value": "12-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "6-8", - "_unit": "hours" - }, - "id": 65 - }, - "5-apb": { - "name": "5-apb", - "properties": { - "summary": "A triple monoamine reuptake inhibitor. This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA.", - "effects": "Users describe effects ranging from total incapacitation and paranoia to euphoria. Largely, effects reported were similar to that of the drug MDA, with euphoria, empathy, sedative, sometimes stimulating effects", - "dose": "Oral Light: 40-60mg Common: 70-100mg Strong: 100mg+", - "onset": "45 -60 minutes", - "duration": "7-8 hours", - "after-effects": "smooth come down/afterglow", - "wiki": "http://wiki.tripsit.me/wiki/5apb", - "detection": "May cause false positives for MDA (1-5 days)", - "aliases": [ - "5apb" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "empathogen", - "habit-forming" - ] - }, - "pretty_name": "5-APB", - "aliases": [ - "5apb" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "40-60mg", - "Common": "70-100mg", - "Strong": "100mg+" - } - }, - "formatted_duration": { - "value": "7-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Users describe effects ranging from total incapacitation and paranoia to euphoria", - "Largely", - "effects reported were similar to that of the drug MDA", - "with euphoria", - "empathy", - "sedative", - "sometimes stimulating effects" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5APB.shtml" - }, - "formatted_aftereffects": { - "value": "smooth" - }, - "id": 66 - }, - "fentanyl": { - "name": "fentanyl", - "properties": { - "dose": "Intranasal Light: 10-25ug Common: 25-50ug Strong: 50-75ug+ | Transdermal Light: 12.5ug/hr Common: 25-50ug/hr Strong: 50-100ug/hr | NOTE: Due to Fentanyl's high potency, it is incredibly difficult to measure safely, and so can easily lead to overdose.", - "onset": "Transdermal: 90-180 minutes. | Buccal: 15-30 ninutes | Insufflated: 5-15 minutes.", - "effects": "Analgesia, euphoria, feelings of relaxation, sedative effects, changes in focus, attention, respiratory depression, nausea, constipation, dry mouth, somnolence, confusion, weakness, sweating, fatigue, dizziness, anxiety", - "duration": "Transdermal: 48-72 hours. | Buccal: 1-4 hours. | Insufflated: 1-4 hours.", - "summary": "Fentanyl is a synthetic opiate analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors and is historically used to treat breakthrough pain. Fentanyl is approximately 100 times more potent than Morphine, and is commonly used as a patch. Sometimes used as an adulterant for heroin, which has led to many overdose deaths.", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "aliases": [ - "fent" - ], - "bioavailability": "Sublingual/Buccal 50% | Insufflated 70% | Transdermal 92%", - "warning": "Risk of post-acute withdrawal effects, including depression, anxiety disorder, psychosis, suicidal ideation in extreme cases." - }, - "pretty_name": "Fentanyl", - "aliases": [ - "fent" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Intranasal": { - "Light": "10-25ug", - "Common": "25-50ug", - "Strong": "50-75ug+" - }, - "Transdermal": { - "Light": "12.5ug/hr", - "Common": "25-50ug/hr", - "Strong": "50-100ug/hr" - } - }, - "formatted_duration": { - "Transdermal": "48-72", - "Buccal": "1-4", - "Insufflated": "1-4", - "_unit": "hours" - }, - "formatted_onset": { - "Transdermal": "90-180", - "Buccal": "15-30", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Analgesia", - "euphoria", - "feelings of relaxation", - "sedative effects", - "changes in focus", - "attention", - "respiratory depression", - "nausea", - "constipation", - "dry mouth", - "somnolence", - "confusion", - "weakness", - "sweating", - "fatigue", - "dizziness", - "anxiety" - ], - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation" - }, - "formatted_aftereffects": { - "value": "Risk" - }, - "dose_note": " NOTE: Due to Fentanyl's high potency, it is incredibly difficult to measure safely, and so can easily lead to overdose.", - "id": 67 - }, - "pv-10": { - "name": "pv-10", - "properties": { - "summary": "Inactive.", - "categories": [ - "inactive" - ] - }, - "pretty_name": "PV-10", - "categories": [ - "inactive" - ], - "id": 68 - }, - "25c-nbome": { - "name": "25c-nbome", - "properties": { - "summary": "A relatively new and popular research chemical. A short acting psychedelic related to 2C-C with similar effects to LSD, though more visual with less of a 'head-trip.' Frequently mis-sold as LSD. Causes an uncomfortable body load and has caused several deaths even within regular dose ranges.", - "dose": "Sublingual Threshold: 50-250ug Light: 250-500ug Common: 500-750ug Strong: 750-1250ug+ | Note: Do not exceed 1500ug.", - "onset": "45-90 minutes.", - "effects": "Mild OEV's, strong CEV's, A sense of well being and contentedness.", - "tolerance": "25c has an extremely prevalent tolerence, with users reporting a strong cross tolerence with LSD, mushrooms, 2c-X, 25x, and DOx chemicals. Tolerence lasts roughly 2 weeks, depending on the user.", - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "aliases": [ - "25c", - "2c-nbome" - ], - "duration": "4-10 hours.", - "after-effects": "1-24 hours.", - "test-kits": "Marquis: Slow Purple. | Mecke: Brown. | Mandelin: No colour change. | Froehde: Yellow. | Liebermann: Yellow > Black. | Ehrlich's Reagent: No colour change." - }, - "pretty_name": "25C-NBOMe", - "aliases": [ - "25c", - "2c-nbome" - ], - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "50-250ug", - "Light": "250-500ug", - "Common": "500-750ug", - "Strong": "750-1250ug+" - } - }, - "formatted_duration": { - "value": "4-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Mild OEV's", - "strong CEV's", - "A sense of well being and contentedness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_25CNBOMe.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Diffraction": "https://psychonautwiki.org/wiki/Diffraction", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Recursion": "https://psychonautwiki.org/wiki/Recursion", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Sublingual numbing": "https://psychonautwiki.org/wiki/Sublingual_numbing", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile hallucinations": "https://psychonautwiki.org/wiki/Tactile_hallucinations", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " Note: Do not exceed 1500ug.", - "sources": { - "_general": [ - "Two cases of severe intoxication associated with analytically confirmed use of the novel psychoactive substances 25B-NBOMe and 25C-NBOMe - http://www.ncbi.nlm.nih.gov/pubmed/24779864" - ] - }, - "id": 69 - }, - "mescaline": { - "name": "mescaline", - "properties": { - "summary": "A psychedelic of the phenethylamine family. Found in psychedelic cacti that have long been used by peoples native to the Southwestern US and Mexico, including Peyote and San Pedro cacti, among others. Can be found as cactus pulp, as an extract from cacti, or as a synthetic substance created in a lab.", - "dose": "Oral Threshold: 100mg Light: 100-200mg Common: 200-300mg Strong: 300-500mg Heavy: 500-700mg+ | NOTE: Doses are for Mescaline HCl", - "onset": "60-180 minutes, sometimes longer.", - "duration": "6-12 hours.", - "after-effects": "3-5 hours.", - "aliases": [ - "buttons", - "mesc", - "san", - "san-pedro" - ], - "marquis": "Strong orange", - "categories": [ - "psychedelic", - "common" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Mescaline", - "aliases": [ - "buttons", - "mesc", - "san", - "san-pedro" - ], - "categories": [ - "psychedelic", - "common" - ], - "formatted_dose": { - "Oral": { - "Threshold": "100mg", - "Light": "100-200mg", - "Common": "200-300mg", - "Strong": "300-500mg", - "Heavy": "500-700mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-180", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Mescaline.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Personal meaning enhancement": "https://psychonautwiki.org/wiki/Personal_meaning_enhancement", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Suggestibility enhancement": "https://psychonautwiki.org/wiki/Suggestibility_enhancement", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "3-5", - "_unit": "hours" - }, - "dose_note": " NOTE: Doses are for Mescaline HCl", - "sources": { - "_general": [ - "CLINICAL SYNDROMES AND BIOCHEMICAL ALTERATIONS FOLLOWING MESCALINE, LYSERGIC ACID DIETHYLAMIDE, PSILOCYBIN AND A COMBINATION OF THE THREE PSYCHOTOM.. - http://www.ncbi.nlm.nih.gov/pubmed/14156873" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Caution" - }, - "nbomes": { - "status": "Caution" - }, - "2c-x": { - "status": "Caution" - }, - "2c-t-x": { - "status": "Caution" - }, - "amt": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Caution", - "note": "The 5-MeO class of tryptamines can be unpredictable in their interactions" - }, - "cannabis": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & Synergy" - }, - "pcp": { - "status": "Low Risk & Synergy" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops" - }, - "mdma": { - "status": "Low Risk & Synergy" - }, - "cocaine": { - "status": "Caution", - "note": "The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops" - }, - "caffeine": { - "status": "Low Risk & No Synergy", - "note": "High doses of caffeine are uncomfortable and this will be magnified by psychedelics" - }, - "alcohol": { - "status": "Low Risk & Decrease" - }, - "ghb/gbl": { - "status": "Low Risk & Decrease" - }, - "opioids": { - "status": "Low Risk & No Synergy" - }, - "tramadol": { - "status": "Unsafe", - "note": "This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures." - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Caution" - }, - "ssris": { - "status": "Low Risk & Decrease" - } - }, - "id": 70 - }, - "flunitrazepam": { - "name": "flunitrazepam", - "properties": { - "dose": "Oral Light: 0.5-1mg Common: 1-2mg Heavy: 2-4mg+", - "summary": "Known as Rohypnol or 'roofies,' this infamous drug has similar qualities to most other benzodiazepines; sedating with strong hypnotic effects. Despite being known as a 'date rape drug' has only been implicated in a small number of such crimes. Danger of respiratory depression in combination with other depressants. May cause amnesia and lowered inhibitions in overdose.", - "aliases": [ - "roofies", - "rohypnol" - ], - "duration": "4-8 hours.", - "onset": "15-30 minutes.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "2-24 hours.", - "dose_to_diazepam": "Flunitrazepam - 1mg ~=10mg Diazepam." - }, - "pretty_name": "Flunitrazepam", - "aliases": [ - "roofies", - "rohypnol" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Heavy": "2-4mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 71 - }, - "4,4-dmar": { - "name": "4,4-dmar", - "properties": { - "summary": "Very closely related stimulant to Aminorex and Pemoline. Was sold as a designer drug for quite awhile under the brand name \"Serotoni\" has been linked to at least 31 deaths. It is a potent SNDRA.", - "dose": "Light: 30-60mg Common: 60-120mg Strong: 120-200mg.", - "onset": "Oral: 15-30 minutes. || Insufflated: 5-15 minutes.", - "after-effects": "1-12 hours.", - "categories": [ - "stimulant", - "empathogen", - "habit-forming", - "tentative" - ], - "aliases": [ - "serotoni", - "4,4-dmap" - ] - }, - "pretty_name": "4,4-DMAR", - "aliases": [ - "serotoni", - "4,4-dmap" - ], - "categories": [ - "stimulant", - "empathogen", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "30-60mg", - "Common": "60-120mg", - "Strong": "120-200mg." - } - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 72 - }, - "dihydrocodeine": { - "name": "dihydrocodeine", - "properties": { - "summary": "A weak semi-synthetic opioid analgesic and antitussive (anti-cough) drug. Often sold as a syrup in combination with aspirin or paracetamol. Not to be confused with the slightly less potent codeine.", - "dose": "Light: 50-100mg Common: 100-150mg Heavy: 150-200mg+ | NOTE: Cold Water Extract the DHC out if the pills are in combination with other substances", - "onset": "30-45 minutes.", - "aliases": [ - "dhc" - ], - "duration": "3-4 hours.", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "bioavailability": "Oral 20%", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-8 hours." - }, - "pretty_name": "Dihydrocodeine", - "aliases": [ - "dhc" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Light:": { - "Light": "50-100mg", - "Common": "100-150mg", - "Heavy": "150-200mg+" - } - }, - "formatted_duration": { - "value": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " NOTE: Cold Water Extract the DHC out if the pills are in combination with other substances", - "id": 73 - }, - "flutazolam": { - "name": "flutazolam", - "properties": { - "summary": "A benzodiazepine derivative. It was invented in Japan, and has mainly stayed in that area. Similar potency to Diazepam, yet produces a more marked sedation and impaired coordination. Usually used as a treatment for Insomnia. A hypnotic and sedative which may cause amnesia and lowered inhibitions in high doses.", - "dose": "Oral Light: 2.5-5mg Common: 5-10mg Strong: 10-15mg.", - "duration": "3-8 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "onset": "10-30 minutes.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Flutazolam", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-15mg." - } - }, - "formatted_duration": { - "value": "3-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 74 - }, - "adrafinil": { - "name": "adrafinil", - "properties": { - "summary": "A prodrug to modafinil, this compound is often used to increase wakefulness and alertness. Due to hepatic metabolism it has a slower onset than modafinil and may cause liver damage in excess. Some users have reported acne as an adverse effect. Unregulated in the US.", - "dose": "Threshold: 100-150mg Light: 150-250mg Common: 250-400mg Strong:400-600mg Heavy: 600mg+", - "onset": "45-120 minutes depending on stomach contents/ect.", - "duration": "8-12 hours.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "nootropic" - ], - "effects": "Stimulation, Dehydration, Headaches, Photophobia, Appetite suppression, Increased heart rate, Dizziness, Nausea, Body odor alteration, Wakefulness, Irritability, Focus enhancement, Thought acceleration, Memory enhancement, Motivation enhancement, Emotion enhancement, Anxiety, Time distortion, Increased music appreciation", - "bioavailability": "Oral: 75-80%.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Adrafinil", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Threshold": "100-150mg", - "Light": "150-250mg", - "Common": "250-400mg", - "Heavy": "600mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Stimulation", - "Dehydration", - "Headaches", - "Photophobia", - "Appetite suppression", - "Increased heart rate", - "Dizziness", - "Nausea", - "Body odor alteration", - "Wakefulness", - "Irritability", - "Focus enhancement", - "Thought acceleration", - "Memory enhancement", - "Motivation enhancement", - "Emotion enhancement", - "Anxiety", - "Time distortion", - "Increased music appreciation" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Adrafinil.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 75 - }, - "etizolam": { - "name": "etizolam", - "properties": { - "summary": "A thienodiazepine anxiolytic. Similar in action to benzodiazepine drugs. Relieves anxiety, causes sedation and mild euphoria. High doses can lead to losing memory of what happened while on the drug. Users often compulsively re-dose frequently leading to accidental blackouts. Can be found in pressed pharmaceutical pills from various countries, clandestine pill presses, or as a powder", - "dose": "Oral Light: 0.5-1mg Common: 1-2mg Strong: 2-4mg+", - "onset": "10-40 minutes", - "duration": "5-8 hours.", - "avoid": "Other depressants such as Alcohol and Opioids.", - "after-effects": "6-24 hours", - "effects": "anxiolytic, hypnotic, sedative, muscle relaxant, amnesia, dystaxia", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "aliases": [ - "etiz", - "etizest", - "etilaam", - "sedekopan", - "depas", - "etizola", - "inxity", - "zoly", - "lamet", - "towa" - ], - "tolerance": "Slower than other benzos, also observed to have reverse-tolerance effect.", - "dose_to_diazepam": "Etizolam - 1mg ~=10mg Diazepam." - }, - "pretty_name": "Etizolam", - "aliases": [ - "etiz", - "etizest", - "etilaam", - "sedekopan", - "depas", - "etizola", - "inxity", - "zoly", - "lamet", - "towa" - ], - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "anxiolytic", - "hypnotic", - "sedative", - "muscle relaxant", - "amnesia", - "dystaxia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Etizolam.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Temporary erectile dysfunction": "https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Etizolam in the treatment of generalized anxiety disorder: a controlled clinical trial. - https://www.ncbi.nlm.nih.gov/pubmed/2572494", - "Molecular and neurochemical evaluation of the effects of etizolam on GABAA receptors under normal and stress conditions. - http://www.ncbi.nlm.nih.gov/pubmed/10083975", - "[A patient with Parkinson's disease complicated by hypothyroidism who developed malignant syndrome after discontinuation of etizolam]. - http://www.ncbi.nlm.nih.gov/pubmed/12424963", - "Low tolerance and dependence liabilities of etizolam: molecular, functional, and pharmacological correlates. - http://www.ncbi.nlm.nih.gov/pubmed/16107249", - "Effects of treatment with etizolam 0.5 mg BID on cognitive performance: a 3-week, multicenter, randomized, double-blind, placebo-controlled, two-tr... - http://www.ncbi.nlm.nih.gov/pubmed/20110024", - "[Comparison of four immunoassay screening devices for detection of benzodiazepine and its metabolites in urine: mainly detection of etizolam, thien... - http://www.ncbi.nlm.nih.gov/pubmed/21485120", - "Etizolam in the treatment of generalized anxiety disorder: a controlled clinical trial. - http://www.ncbi.nlm.nih.gov/pubmed/2572494" - ] - }, - "id": 76 - }, - "zolazepam": { - "name": "zolazepam", - "properties": { - "summary": "A substance that is structurally related to benzodiazepines. Is only used in Veterinary medicine. It is usually used in tandem with either the potent NMDA antagonist Tiletamine (at a 1:1 ratio) or with the α2 adrenergic receptor agonist Xylazine. Is roughly around four times the potency of Diazepam. Yet is water soluable.", - "onset": "Oral: 10-30 minutes. | Insufflated: 5-10 minutes. | Intramuscular: 1-5 minutes.", - "duration": "Oral: 4-6 hours. | Insufflated: 2-3 hours. | Intramuscular: 2-4 hours.", - "dose": "Oral Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg+ | Insufflated Light: 1-3mg Common: 3-6mg Strong: 6-12mg+ | Intramuscular Light: 1-3mg Common: 3-5mg Strong: 5-10mg+", - "after-effects": "Oral: 1-6 hours. | Insufflated: 1-4 hours. | Intramuscular: 1-3 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Zolazepam", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - }, - "Insufflated": { - "Light": "1-3mg", - "Common": "3-6mg", - "Strong": "6-12mg+" - }, - "Intramuscular": { - "Light": "1-3mg", - "Common": "3-5mg", - "Strong": "5-10mg+" - } - }, - "formatted_duration": { - "Oral": "4-6", - "Insufflated": "2-3", - "Intramuscular": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "Insufflated": "5-10", - "Intramuscular": "1-5", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "1-6", - "Insufflated": "1-4", - "Intramuscular": "1-3", - "_unit": "hours" - }, - "id": 77 - }, - "barbital": { - "name": "barbital", - "properties": { - "summary": "The first commercially available barbiturate. Was used commonly as a sleeping aid until the 1950s.", - "dose": "Common: 650-970mg.", - "onset": "15-30 minutes.", - "duration": "6-12 hours.", - "categories": [ - "barbiturate", - "habit-forming", - "depressant" - ], - "avoid": "All other CNS depressants." - }, - "pretty_name": "Barbital", - "categories": [ - "barbiturate", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Common": "650-970mg." - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "id": 78 - }, - "25i-nbf": { - "name": "25i-nbf", - "properties": { - "summary": "Is a derivate of the psychedelic 2C-I. Was sold breifly in a few countries before being banned. Based purely on the pharmacological evidence it'll be between 6-8x less potent than it's parent compound 25I-NBOMe.", - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ], - "test-kits": "Marquis: Dark Green. | Mecke: Orange > Black. | Mandelin: Orange > Black. | Froehde: Orange > Black. | Liebermann: Orange > Black. | Ehrlich: No colour change. | Gallic Acid: Orange > Black." - }, - "pretty_name": "25I-NBF", - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ], - "id": 79 - }, - "oxazepam": { - "name": "oxazepam", - "properties": { - "summary": "A prescription benzodiazepine with intermediate duration and half life. A sedative and hypnotic which may cause lowered inhibitions and amnesia in higher doses.", - "duration": "4-6 hours.", - "onset": "60-120 minutes.", - "dose": "Light: 5-10mg Common: 10-30mg Strong: 30-45mg+", - "effects": "Typical benzodiazepine effects. Amnesic, anxiolytic, anticonvulsant, hypnotic, sedative.", - "after-effects": "1-10 hours.", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "avoid": "All other CNS depressants.", - "aliases": [ - "serax" - ], - "dose_to_diazepam": "Oxazepam - 20mg ~=10mg Diazepam." - }, - "pretty_name": "Oxazepam", - "aliases": [ - "serax" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-30mg", - "Strong": "30-45mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Typical benzodiazepine effects", - "Amnesic", - "anxiolytic", - "anticonvulsant", - "hypnotic", - "sedative", - "" - ], - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "id": 80 - }, - "mebroqualone": { - "name": "mebroqualone", - "properties": { - "duration": "Oral: 60-120 minutes. | Sublingual: 45-90 minutes. | Insufflated: 30-60 minutes. | Vapourized: 20-40 minutes.", - "dose": "Sublingual Threshold: 3-5mg Light: 5-8mg Common: 8-15mg Strong: 15-20mg. | Vaporized Threshold: 2-3mg Light: 3-5mg Common: 5-10mg Strong: 10-20mg+", - "summary": "A short acting analogue of Methaqualone, that is much more potent.", - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "mbq" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-4 hours.", - "onset": "Oral: 10-20 minutes. | Sublingual: 5-15 minutes. | Insufflated: 5-10 minutes. | Vapourized: 1-2 minutes." - }, - "pretty_name": "Mebroqualone", - "aliases": [ - "mbq" - ], - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "3-5mg", - "Light": "5-8mg", - "Common": "8-15mg", - "Strong": "15-20mg." - }, - "Vaporized": { - "Threshold": "2-3mg", - "Light": "3-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "Oral": "60-120", - "Sublingual": "45-90", - "Insufflated": "30-60", - "Vapourized": "20-40", - "_unit": "minutes" - }, - "formatted_onset": { - "Oral": "10-20", - "Sublingual": "5-15", - "Insufflated": "5-10", - "Vapourized": "1-2", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 81 - }, - "aleph-2": { - "name": "aleph-2", - "properties": { - "summary": "A very rare Phenethylamine, also known as DOT-2, it is the DOx analogue of 2C-T-2. Very little human use recorded. Described as being quite long and highly visual. Likely to be potent, with a reported threshold dose of 3mg.", - "onset": "40-120 minutes", - "duration": "6-18 hours.", - "after-effects": "12-24 hours", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "aliases": [ - "dot-2", - "dot2", - "aleph2" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "ALEPH-2", - "aliases": [ - "dot-2", - "dot2", - "aleph2" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "none": { - "NOTE": "Varies" - } - }, - "formatted_duration": { - "value": "6-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "40-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "12-24", - "_unit": "hours" - }, - "id": 82 - }, - "pramiracetam": { - "name": "pramiracetam", - "properties": { - "summary": "A CNS stimulant that is a nootropic, that belongs to the racetam family of compounds. Much more potent than Piracetam while appearing to work on similar mechanisms.", - "dose": "Common: 400-1200mg | Note: Usually taken two or three times a day. So 400mg taken three times a day. Or 600mg three times a day.", - "onset": "15-30 minutes.", - "duration": "4-6 hours.", - "after-effects": "1-2 hours.", - "categories": [ - "nootropic" - ] - }, - "pretty_name": "Pramiracetam", - "categories": [ - "nootropic" - ], - "formatted_dose": { - "Common:": { - "Common": "400-1200mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "dose_note": " Note: Usually taken two or three times a day. So 400mg taken three times a day. Or 600mg three times a day.", - "id": 83 - }, - "25i-nbome": { - "name": "25i-nbome", - "properties": { - "dose": "Sublingual Threshold: 50-250ug Light: 200-500ug Common: 500-750ug Strong: 700-1000ug+ | Note: Do not exceed 1500ug.", - "duration": "5-10 hours.", - "summary": "A relatively new and popular research chemical with psychedelic properties. Users report an uncomfortable body load with very strong visuals, though with less of a mental aspect than most psychedelics. Commonly mis-sold as LSD, since it is much cheaper to produce. Is considered quite unsafe, and has caused several deaths at 'regular' doses.", - "onset": "45-90 minutes.", - "after-effects": "6-24 hours", - "tolerance": "25i-nbome has an extremely prevalent tolerance, with users reporting a strong cross tolerance with LSD, mushrooms, 2C-*, DO* and other 25* chemicals. Tolerance lasts roughly 2 weeks depending on the user.", - "wiki": "http://wiki.tripsit.me/wiki/NBOMes", - "aliases": [ - "25i", - "2-c-i-nbome", - "25-i" - ], - "marquis": "Orange", - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "test-kits": "Marquis: Orange > Black. | Mecke: Brown > Black. | Mandelin: Brown > Black. | Froehde: Yellow | Ehrlich: No colour change." - }, - "pretty_name": "25I-NBOMe", - "aliases": [ - "25i", - "2-c-i-nbome", - "25-i" - ], - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "50-250ug", - "Light": "200-500ug", - "Common": "500-750ug", - "Strong": "700-1000ug+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_25INBOMe.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Feelings of impending doom": "https://psychonautwiki.org/wiki/Feelings_of_impending_doom", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Laughter": "https://psychonautwiki.org/wiki/Laughter", - "Magnification": "https://psychonautwiki.org/wiki/Magnification", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Sublingual numbing": "https://psychonautwiki.org/wiki/Sublingual_numbing", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "dose_note": " Note: Do not exceed 1500ug.", - "sources": { - "_general": [ - "Severe clinical toxicity associated with analytically confirmed recreational use of 25I-NBOMe: case series - http://www.ncbi.nlm.nih.gov/pubmed/23731373" - ] - }, - "id": 84 - }, - "flubromazepam": { - "name": "flubromazepam", - "properties": { - "dose": "Light: 2-4mg Common: 4-8mg Strong: 8-12mg+", - "summary": "A somewhat common benzodiazepine drug known for its extreme duration, with effects for larger doses reaching up to three days. Sedative, hypnotic and anxiolytic, this compound is an analogue of Phenazepam. First discovered in the 1960s, it was never marketed as a licit drug, but has recently become available as an RC. Not to be confused with Flubromazolam.", - "onset": "15-90 minutes", - "duration": "12-18 hours", - "after-effects": "36+ hours", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "dose_to_diazepam": "Flubromazepam - 6-8mg ~=10mg Diazepam." - }, - "pretty_name": "Flubromazepam", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2-4mg", - "Common": "4-8mg", - "Strong": "8-12mg+" - } - }, - "formatted_duration": { - "value": "12-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "36+", - "_unit": "hours" - }, - "id": 85 - }, - "5-bpdi": { - "name": "5-bpdi", - "properties": { - "summary": "An analogue of a-PHP, which has been described as having an extremely similar effect profile, with some users noting that it may be slightly lighter and with less of an urge to redose. However, little record of the safety of human use exists.", - "categories": [ - "habit-forming", - "research-chemical", - "stimulant", - "tentative" - ], - "dose": "Light: 7.5-10mg Common: 10-25mg Strong: 25-45mg Heavy: 45+mg.", - "onset": "Oral: 15-30 minutes. Insufflated: 5-10 minutes.", - "duration": "Oral: 4-8 hours. Insufflated: 2-5 hours.", - "after-effects": "3-8 hours." - }, - "pretty_name": "5-BPDI", - "categories": [ - "habit-forming", - "research-chemical", - "stimulant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "7.5-10mg", - "Common": "10-25mg", - "Strong": "25-45mg", - "Heavy": "45+mg." - } - }, - "formatted_duration": { - "Oral": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "3-8", - "_unit": "hours" - }, - "id": 86 - }, - "ab-fubinaca": { - "name": "ab-fubinaca", - "properties": { - "summary": "Arguably the most common synthetic cannabinoid, AB-FUBINACA was originally developed by Pfizer as an analgesic, but has since abandoned for medical use. It has since found a following in the RC community, however it's extremely high potency and inclusion in synthetic blends makes it dangerous, and it has killed in overdose. Exercise caution.", - "duration": "Vaporized: 1-2 hours | Oral: 5-15 hours", - "dose": "Vaporized Light: 0.25-0.5mg Common: 0.5-1.5mg Strong: 1.5-3mg Heavy: 3+mg | Oral Light: 0.25-0.5mg Common: 0.5-1.5mg Strong: 1.5-3mg Heavy: 3+mg", - "onset": "Vaporized: 1-5 minutes | Oral: 30-240 minutes", - "effects": "Euphoric, stimulating high, increases creativity and appetite, also short term memory deficits, similar to Cannabis", - "after-effects": "Vaporized: 1-2 hours | Oral: 2-10 hours", - "aliases": [ - "ab-fub" - ], - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "common" - ] - }, - "pretty_name": "AB-FUBINACA", - "aliases": [ - "ab-fub" - ], - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "common" - ], - "formatted_dose": { - "Vaporized": { - "Light": "0.25-0.5mg", - "Common": "0.5-1.5mg", - "Strong": "1.5-3mg", - "Heavy": "3+mg" - }, - "Oral": { - "Light": "0.25-0.5mg", - "Common": "0.5-1.5mg", - "Strong": "1.5-3mg", - "Heavy": "3+mg" - } - }, - "formatted_duration": { - "Vaporized": "1-2", - "Oral": "5-15", - "_unit": "hours" - }, - "formatted_onset": { - "Vaporized": "1-5", - "Oral": "30-240", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoric", - "stimulating high", - "increases creativity and appetite", - "also short term memory deficits", - "similar to Cannabis" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_ABFUBINACA.shtml" - }, - "formatted_aftereffects": { - "Vaporized": "1-2", - "Oral": "2-10", - "_unit": "hours" - }, - "id": 87 - }, - "3-ho-pce": { - "name": "3-ho-pce", - "properties": { - "summary": "A rare and very potent PCP analogue, eight times more potent than PCP as NMDA receptor antagonist and also a μ-opioid receptor agonist. Similar in structure to methoxetamine.", - "duration": "3-4 hours.", - "onset": "20-40 minutes.", - "aliases": [ - "3hopce" - ], - "dose": "Oral Threshold 1-2mg Light: 2-5mg Common: 5-10mg's Strong: 10-15mg's", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "after-effects": "2 hours to a month." - }, - "pretty_name": "3-HO-PCE", - "aliases": [ - "3hopce" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10-15mg" - } - }, - "formatted_duration": { - "value": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2", - "_unit": "hours" - }, - "id": 88 - }, - "4-benzylpiperidine": { - "name": "4-benzylpiperidine", - "properties": { - "summary": "A dopamine releasing agent with weak serotonin releasing properties. Little evidence of human use. Potentially dangerous in overdose given MAOI + monoamine releasing properties.", - "dose": "Oral Light: 75-125mg Common: 125-200mg Strong: 200-350mg Heavy: 350mg+.", - "duration": "2-5 hours", - "aliases": [ - "4-pmpd" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "onset": "10-45 minutes." - }, - "pretty_name": "4-Benzylpiperidine", - "aliases": [ - "4-pmpd" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "75-125mg", - "Common": "125-200mg", - "Strong": "200-350mg", - "Heavy": "350mg+." - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "id": 89 - }, - "eszopiclone": { - "name": "eszopiclone", - "properties": { - "summary": "The d-isomer of Zopiclone, this drug is a potent hypnotic 'Z' drug often used to treat insomnia. High doses may cause amnesia, delirium and lowered inhibitions. Should not be combined with any depressants. Limited recreational value.", - "categories": [ - "depressant", - "habit-forming" - ], - "effects": "anxiolytic, sedative, muscle relaxant, amnesia, dystaxia, hypnotic", - "dose": "Light: 0.5-1mg Common: 1-2mg Strong: 2-4mg+", - "onset": "15-30 minutes.", - "duration": "6-10 hours.", - "after-effects": "1-12 hours.", - "avoid": "All other CNS depressants." - }, - "pretty_name": "Eszopiclone", - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg+" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "anxiolytic", - "sedative", - "muscle relaxant", - "amnesia", - "dystaxia", - "hypnotic" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 90 - }, - "tianeptine": { - "name": "tianeptine", - "properties": { - "onset": "15-45 minutes.", - "duration": "4-6 hours.", - "summary": "A Tricyclic antidepressant, that has quite unique pharmacological properties than others in its class. Such as the possible indirect action on NMDA/AMPA and a full agonist at the μ-opioid receptor. While abuse of this substance is uncommon, it has been shown in a few countries.", - "categories": [ - "habit-forming", - "depressant", - "opioid" - ], - "dose": "Light: 7.5mg Common: 12.5mg Strong: 17mg Note: Tianeptine is reported to have opioid-like effects at high doses, but this is offset by an increased risk of liver damage", - "after-effects": "1-8 hours." - }, - "pretty_name": "Tianeptine", - "categories": [ - "habit-forming", - "depressant", - "opioid" - ], - "formatted_dose": { - "Oral": { - "Light": "7.5mg", - "Common": "12.5mg", - "Strong": "17mg", - "Note": "Tianeptine" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Bronchodilation": "https://psychonautwiki.org/wiki/Bronchodilation", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Physical fatigue": "https://psychonautwiki.org/wiki/Physical_fatigue", - "Rejuvenation": "https://psychonautwiki.org/wiki/Rejuvenation", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 91 - }, - "6-mddm": { - "name": "6-mddm", - "properties": { - "summary": "Semisynthetic opioid that is a derivative of Hydromorphone with little history of human use. Roughly around ~80x the potency of Morphine. Structurally related to Desomorphine.", - "onset": "1-15 minutes.", - "duration": "4-6 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "opioid", - "habit-forming", - "tentative", - "depressant" - ], - "aliases": [ - "6-methylenedihydrodesoxymorphine" - ], - "dose": "Light: 125ug Common: 187-250ug Strong: 375ug+ | NOTE: These dosages are based off the potency and converted to what we have with Morphine's dose. Further research is required.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-10 hours." - }, - "pretty_name": "6-MDDM", - "aliases": [ - "6-methylenedihydrodesoxymorphine" - ], - "categories": [ - "opioid", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Light:": { - "Light": "125ug", - "Common": "187-250ug", - "Strong": "375ug+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1-15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "dose_note": " NOTE: These dosages are based off the potency and converted to what we have with Morphine's dose. Further research is required.", - "id": 92 - }, - "yerba-mate": { - "name": "yerba-mate", - "properties": { - "summary": "Is marketed for its ability to suppress appetite and burn fat. Yet only with high doses. It has a quite high ratio of caffeine. It has anti-inflammatory properties.", - "dose": "Common: 1000-1500mg | This is spread out over a day.", - "onset": "10-30 minutes.", - "duration": "4-6 hours.", - "after-effects": "1-4 hours.", - "categories": [ - "common", - "stimulant", - "habit-forming", - "nootropic" - ] - }, - "pretty_name": "YERBA-MATE", - "categories": [ - "common", - "stimulant", - "habit-forming", - "nootropic" - ], - "formatted_dose": { - "Common:": { - "Common": "1000-1500mg" - }, - "This": {} - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 93 - }, - "4-ho-mcpt": { - "name": "4-ho-mcpt", - "properties": { - "summary": "Novel synthetic tryptamine that is the cyclopropyl homologue of Psilocin. Not much is known about anything.", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "onset": "20-40 minutes." - }, - "pretty_name": "4-HO-MCPT", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "id": 94 - }, - "mbzp": { - "name": "mbzp", - "properties": { - "summary": "A stimulant drug which is a derivative of BZP.", - "onset": "30-45 minutes.", - "duration": "4-6 hours", - "after-effects": "2-4 hours, yet can be much long with extended doses/ect.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "aliases": [ - "methylbenylpiperazine" - ], - "dose": "Oral Light: 50-80mg Common: 80-120mg Strong: 120-160mg Heavy: 160-200mg+" - }, - "pretty_name": "MBZP", - "aliases": [ - "methylbenylpiperazine" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-80mg", - "Common": "80-120mg", - "Strong": "120-160mg", - "Heavy": "160-200mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 95 - }, - "25e-nbome": { - "name": "25e-nbome", - "properties": { - "duration": "5-10 hours.", - "aliases": [ - "25e" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "summary": "A potent psychedelic phenethylamine and derivative of 2C-E, usually sold on blotters. May be mis-sold as LSD. Effects include vivid hallucinations, stimulation, heavy body load and vasoconstriction. At high doses vasoconstriction can endanger life, exercise caution.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "dose": "Sublingual Threshold: 50-100ug Light: 150-300ug Common: 300-600ug Strong: 600-1000ug. Insufflated Light: 50-200ug Common: 200-400ug Strong: 400-800ug.", - "onset": "15-60 minutes.", - "after-effects": "2-10 hours.", - "warning": "Do not exceed 2mg+ of this compound.", - "test-kits": "Marquis: Red > Yellow. | Mecke: Green. | Mandelin: Red. | Ehrlich: No colour change." - }, - "pretty_name": "25E-NBOMe", - "aliases": [ - "25e" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "50-100ug", - "Light": "50-200ug", - "Common": "200-400ug", - "Strong": "400-800ug." - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "2-10", - "_unit": "hours" - }, - "id": 96 - }, - "5-meo-malt": { - "name": "5-meo-malt", - "properties": { - "summary": "A new and uncommon psychedelic tryptamine related to 5-MeO-DALT. Little is known about it, but its effects are probably similar to other psychedelic tryptamines.", - "dose": "Oral Light: 15-25mg Common: 25-50mg Strong: 50mg+ | Insufflated Light: 5-10mg Common: 10-20mg Strong: 20mg+ | Vapourized Light: 5-10mg Common: 10-15mg Strong: 15-20mg | Note: Due to the massive amount of reports not correlating to the others please start very low and titrate up.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "onset": "Oral: 5-30 minutes. | Insufflated: 5-15 minutes. | Vapourized: 1-5 minutes.", - "duration": "Oral: 2-4 hours. | Insufflated: 1-3 hours. | Vapourized: 0.5-1.5 hours." - }, - "pretty_name": "5-MeO-MALT", - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "15-25mg", - "Common": "25-50mg", - "Strong": "50mg+" - }, - "Insufflated": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20mg+" - }, - "Vapourized": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-20mg" - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "1-3", - "Vapourized": "0.5-1.5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "5-30", - "Insufflated": "5-15", - "Vapourized": "1-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "dose_note": " Note: Due to the massive amount of reports not correlating to the others please start very low and titrate up.", - "id": 97 - }, - "mdma": { - "name": "mdma", - "properties": { - "dose": "Oral Light: 40-75mg Common: 75-125mg Strong: 125-175mg Heavy: 175mg+ | Insufflated/Rectal Light: 30-70mg Common: 70-120mg Strong: 120-165mg Heavy: 165mg+ | NOTE: Higher doses increase neurotoxic effects", - "onset": "20-70 minutes", - "duration": "3-5 hours", - "after-effects": "1-72 hours.", - "summary": "The world's most popular empathogen with powerful pro-social effects. Has been strongly linked to cognitive decline in excess. Popular at parties, it is often sold in powder or in pills, and may be adulterated with other similar chemicals.", - "detection": "1-3 days single use, 3-5 days heavy use", - "aliases": [ - "molly", - "ecstasy", - "adam", - "xtc", - "mandy", - "x", - "md" - ], - "marquis": "Black (may have purple tint)", - "categories": [ - "stimulant", - "psychedelic", - "empathogen", - "habit-forming", - "common" - ], - "general-advice": "Only roll every 2-3 months.", - "wiki": "http://wiki.tripsit.me/wiki/MDMA" - }, - "pretty_name": "MDMA", - "aliases": [ - "molly", - "ecstasy", - "adam", - "xtc", - "mandy", - "x", - "md" - ], - "categories": [ - "stimulant", - "psychedelic", - "empathogen", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "40-75mg", - "Common": "75-125mg", - "Strong": "125-175mg", - "Heavy": "175mg+" - }, - "Insufflated/Rectal": { - "Light": "30-70mg", - "Common": "70-120mg", - "Strong": "120-165mg", - "Heavy": "165mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-70", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MDMA.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal109.shtml" - }, - "formatted_aftereffects": { - "value": "1-72", - "_unit": "hours" - }, - "dose_note": " NOTE: Higher doses increase neurotoxic effects", - "sources": { - "_general": [ - "Alpha-lipoic acid prevents 3,4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity - http://www.ncbi.nlm.nih.gov/pubmed/10619665", - "Involvement of free radicals in MDMA-induced neurotoxicity in mice. - http://www.ncbi.nlm.nih.gov/pubmed/11435997", - "Methamphetamine and MDMA (ecstasy) neurotoxicity: 'of mice and men'. - http://www.ncbi.nlm.nih.gov/pubmed/15370888", - "The neurotoxic effects of 3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine on serotonin, dopamine, and GABA-ergic terminals - http://www.ncbi.nlm.nih.gov/pubmed/15474609", - "MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment. - http://www.ncbi.nlm.nih.gov/pubmed/16220332", - "Pharmacological aspects of the combined use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and gamma-hydroxybutyric acid (GHB) - http://www.ncbi.nlm.nih.gov/pubmed/16234132", - "3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings. - http://www.ncbi.nlm.nih.gov/pubmed/16541247", - "The effects of fluoxetine on the subjective and physiological effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans - http://www.ncbi.nlm.nih.gov/pubmed/17047932", - "Neurogenic bladder and chronic urinary retention associated with MDMA abuse. - http://www.ncbi.nlm.nih.gov/pubmed/18570171", - "THC Prevents MDMA Neurotoxicity in Mice - http://www.ncbi.nlm.nih.gov/pubmed/20174577", - "Effects of a beta-blocker on the cardiovascular response to MDMA (Ecstasy). - http://www.ncbi.nlm.nih.gov/pubmed/20378736", - "Neurotoxicity of ecstasy (MDMA): an overview - http://www.ncbi.nlm.nih.gov/pubmed/20420572", - "MDMA: interactions with other psychoactive drugs - http://www.ncbi.nlm.nih.gov/pubmed/21756931", - "MDMA and temperature: a review of the thermal effects of 'Ecstasy' in humans. - http://www.ncbi.nlm.nih.gov/pubmed/21924843", - "MDMA (ecstasy) effects on actual driving performance before and after sleep deprivation, as function of dose and concentration in blood and oral... - http://www.ncbi.nlm.nih.gov/pubmed/21952668", - "MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. - http://www.ncbi.nlm.nih.gov/pubmed/23179355", - "MDMA Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner. - http://www.ncbi.nlm.nih.gov/pubmed/23457892", - "Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: implications for the pathogenesis of free radical - http://www.ncbi.nlm.nih.gov/pubmed/23681166", - "MDMA-induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurons. - http://www.ncbi.nlm.nih.gov/pubmed/2452449", - "MDMA, cortisol, and heightened stress in recreational ecstasy users. - http://www.ncbi.nlm.nih.gov/pubmed/25014666", - "A study of the mechanism of MDMA ('ecstasy')-induced neurotoxicity of 5-HT neurones using chlormethiazole, dizocilpine and other protective compounds. - http://www.ncbi.nlm.nih.gov/pubmed/7516800", - "Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum. - http://www.ncbi.nlm.nih.gov/pubmed/7542394", - "MDMA (ecstasy) inhibition of MAO type A and type B: comparisons with fenfluramine and fluoxetine (Prozac). - http://www.ncbi.nlm.nih.gov/pubmed/7945733", - "Ecstasy use and serotonin syndrome: a neglected danger to adolescents and young adults prescribed selective serotonin reuptake inhibitors. - https://www.ncbi.nlm.nih.gov/pubmed/24006318", - "3,4-Methylenedioxymethamphetamine (ecstasy) and alcohol interactions in humans: psychomotor performance, subjective effects, and pharmacokinetics. - http://www.ncbi.nlm.nih.gov/pubmed/11752122", - "Putting an Ecstasy test kit to the test: harm reduction or harm induction? - http://www.ncbi.nlm.nih.gov/pubmed/14594341", - "MDMA Vasopressin and oxytocin secretion in response to the consumption of ecstasy in a clubbing population. - http://www.ncbi.nlm.nih.gov/pubmed/16574714", - "Monoamine oxidase-B mediates ecstasy-induced neurotoxic effects to adolescent rat brain mitochondria. - http://www.ncbi.nlm.nih.gov/pubmed/17881526", - "Increased oxytocin concentrations and prosocial feelings in humans after ecstasy (3,4-methylenedioxymethamphetamine) administration. - http://www.ncbi.nlm.nih.gov/pubmed/19562632", - "Neurotoxicity of ecstasy (MDMA): an overview. - http://www.ncbi.nlm.nih.gov/pubmed/20420572", - "Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats - http://www.ncbi.nlm.nih.gov/pubmed/21615721", - "Neurotoxicity of ecstasy and its metabolites in human dopaminergic differentiated SH-SY5Y cells. - http://www.ncbi.nlm.nih.gov/pubmed/23194825", - "Neuroprotective properties of melissa officinalis L. Extract against ecstasy-induced neurotoxicity. - http://www.ncbi.nlm.nih.gov/pubmed/23671824", - "Ecstasy use and serotonin syndrome: a neglected danger to adolescents and young adults prescribed selective serotonin reuptake inhibitors. - http://www.ncbi.nlm.nih.gov/pubmed/24006318", - "MDMA, cortisol, and heightened stress in recreational ecstasy users - http://www.ncbi.nlm.nih.gov/pubmed/25014666", - "History of MDMA - http://www.mdma.net/merck/history-ecstasy.html", - "Study associating long-term serotonergic injury from use of MDMA - http://www.ncbi.nlm.nih.gov/pubmed/7643196", - "Even after abstaining as long as 2.5 years, verbal memory deficits were still present in ex-mdma abuserd, indicating that the neurotoxicity may have some permanent damage features - http://m.jop.sagepub.com/content/20/2/211.short", - "http://onlinelibrary.wiley.com/doi/10.1002/nrc.20023/abstract Potentiation of (DL)-3,4-methylenedioxymethamphetamine (MDMA)-induced toxicity by the serotonin 2A receptior partial agonist d-lysergic acid diethylamide (LSD), and the protection of same by the serotonin 2A/2C receptor antagonist MDL 11,939" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Caution", - "note": "The combined stimulating effects of the two can be uncomfortable. Coming down on the MDMA while the DOx is still active can be quite anxiogenic. " - }, - "nbomes": { - "status": "Caution" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Caution" - }, - "amt": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Caution", - "note": "Some of the 5-MeO tryptamines are a bit unpredictable and should be mixed with MDMA with care" - }, - "cannabis": { - "status": "Low Risk & Synergy", - "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible." - }, - "ketamine": { - "status": "Low Risk & Synergy", - "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury." - }, - "mxe": { - "status": "Caution", - "note": "There have been reports of risky serotonergic interactions when the two are taken at the same time, but MXE taken to the end of an MDMA experience does not appear to cause the same issues." - }, - "dxm": { - "status": "Dangerous" - }, - "pcp": { - "status": "Unsafe", - "note": "This combination can easily lead to hypermanic states" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Low Risk & Synergy", - "note": "Amphetamines increase the neurotoxic effects of MDMA" - }, - "cocaine": { - "status": "Caution", - "note": "Cocaine blocks some of the desirable effects of MDMA while increasing the risk of heart attack." - }, - "caffeine": { - "status": "Caution", - "note": "Caffiene is not really necessary with MDMA and increases any neurotoxic effects from MDMA" - }, - "alcohol": { - "status": "Caution", - "note": "Both MDMA and alcohol cause dehydration. Approach this combination with caution, moderation and sufficient hydration. More than a small amount of alcohol will dull the euphoria of MDMA" - }, - "ghb/gbl": { - "status": "Caution", - "note": "Large amounts of GHB/GBL may overwhelm the effects of MDMA on the comedown." - }, - "opioids": { - "status": "Low Risk & No Synergy" - }, - "tramadol": { - "status": "Dangerous", - "note": "Tramadol and stimulants both increase the risk of seizures." - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Dangerous", - "note": "MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably. MAO-A inhibitors with MDMA will lead to hypertensive crises." - }, - "ssris": { - "status": "Low Risk & Decrease" - } - }, - "id": 98 - }, - "3-oh-phenazepam": { - "name": "3-oh-phenazepam", - "properties": { - "dose": "Light: 0.5-1mg Common: 1-2mg Heavy: 2-4mg", - "summary": "The 3-OH analogue of Phenazepam, which cuts the half life down quite a bit. Psychoactive effects are mostly lead by its metabolites, rather than the drug itself.", - "onset": "30-90 minutes.", - "duration": "10-24 hours.", - "avoid": "All other CNS depressants.", - "after-effects": "2-24 hours.", - "aliases": [ - "3-ho-phenazepam", - "3hophenazepam", - "3ohphenazepam", - "3-ho-p", - "3hop", - "3-oh-p", - "3ohp", - "3-hydroxyphenazepam" - ], - "categories": [ - "tentative", - "research-chemical", - "benzodiazepine", - "habit-forming", - "depressant" - ] - }, - "pretty_name": "3-OH-PHENAZEPAM", - "aliases": [ - "3-ho-phenazepam", - "3hophenazepam", - "3ohphenazepam", - "3-ho-p", - "3hop", - "3-oh-p", - "3ohp", - "3-hydroxyphenazepam" - ], - "categories": [ - "tentative", - "research-chemical", - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Heavy": "2-4mg" - } - }, - "formatted_duration": { - "value": "10-24", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 99 - }, - "nefiracetam": { - "name": "nefiracetam", - "properties": { - "summary": "Nootropic compound of the racetam family. Seems to enhance both GABAergic and cholinergic signalling. Long term use appears to be neuroprotective. Fat soluble.", - "dose": "Common: 150-450mg. | NOTE: Usually divided into three doses. Roughly around 0.5mg-1.6mg/kg.", - "onset": "30-60 minutes.", - "duration": "6-12 hours.", - "categories": [ - "nootropic", - "tentative", - "research-chemical" - ], - "after-effects": "1-8 hours.", - "aliases": [ - "nerfiracetam" - ] - }, - "pretty_name": "Nefiracetam", - "aliases": [ - "nerfiracetam" - ], - "categories": [ - "nootropic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Common:": { - "Common": "150-450mg." - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " NOTE: Usually divided into three doses. Roughly around 0.5mg-1.6mg/kg.", - "id": 100 - }, - "mdea": { - "name": "mdea", - "properties": { - "summary": "A quite rare empathogen closely related to MDMA. Yet is less potent than the prior.", - "onset": "30-60 minutes.", - "duration": "3-6 hours.", - "dose": "Light: 80-100mg Common: 100-150mg Strong: 150-200mg.", - "categories": [ - "stimulant", - "empathogen", - "tentative" - ], - "aliases": [ - "mde", - "eve" - ], - "after-effects": "1-36 hours." - }, - "pretty_name": "MDEA", - "aliases": [ - "mde", - "eve" - ], - "categories": [ - "stimulant", - "empathogen", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "80-100mg", - "Common": "100-150mg", - "Strong": "150-200mg." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-36", - "_unit": "hours" - }, - "id": 101 - }, - "cyclopentyl-fentanyl": { - "name": "cyclopentyl-fentanyl", - "properties": { - "summary": "An analogue of fentanyl that is unknown in literature, seems to be less potent than its former being Acetyl-Fentanyl. Yet reports have yet to surface. Be careful.", - "aliases": [ - "cp-f", - "cpf" - ], - "categories": [ - "opioid", - "tentative", - "research-chemical", - "depressant", - "habit-forming" - ] - }, - "pretty_name": "CYCLOPENTYL-FENTANYL", - "aliases": [ - "cp-f", - "cpf" - ], - "categories": [ - "opioid", - "tentative", - "research-chemical", - "depressant", - "habit-forming" - ], - "id": 102 - }, - "dibutylone": { - "name": "dibutylone", - "properties": { - "summary": "Inactive.", - "categories": [ - "inactive" - ] - }, - "pretty_name": "Dibutylone", - "categories": [ - "inactive" - ], - "id": 103 - }, - "pentazocine": { - "name": "pentazocine", - "properties": { - "summary": "A synthetic opioid used as an analgesic. It is only used IM and IV in the medical field and has respiratory depressant effects. It is pregnancy category C and schedule IV in the US.", - "aliases": [ - "talwin" - ], - "dose": "IM Light: 10-20mg Common: 20mg-30mg Strong: 30-60mg ( Do NOT Exceed 60mg) | IV Light: 5-10mg Common: 10-20mg Strong: 30mg (Do NOT Exceed 30mg)", - "duration": "IM: 2-3 hours | IV: 2-3 hours", - "avoid": "All other CNS depressants", - "onset": "IM 15-20 minutes | IV 2-3 minutes", - "categories": [ - "habit-forming", - "depressant", - "opioid" - ], - "warning": "When mixed with a barbituate in a syringe it will crystallize which can be fatal.", - "bioavailability": "Oral 20%", - "after-effects": "1-12 hours." - }, - "pretty_name": "Pentazocine", - "aliases": [ - "talwin" - ], - "categories": [ - "habit-forming", - "depressant", - "opioid" - ], - "formatted_dose": { - "IM": { - "Light": "10-20mg", - "Common": "20mg-30mg", - "Strong": "30-60mg" - }, - "IV": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "30mg" - } - }, - "formatted_duration": { - "IM": "2-3", - "IV": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "IM": "15-20", - "IV": "2-3", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "sources": { - "_general": [ - "information for dose duration onset warning and summary - Book - 2015 Jones and Bartlett Nurse's drug handbook fourteenth edition - page 929" - ] - }, - "id": 104 - }, - "3-mec": { - "name": "3-mec", - "properties": { - "summary": "Another cathinone based stimulant, that is weaker than 4-MEC. Very few reports since it is quite unpopular.", - "dose": "Oral Light: 50-100mg Common: 100-175mg Strong: 175-250mg+ | Insufflated: Light: 25-50mg Common: 50-100mg Strong: 100-150mg+", - "onset": "Oral: 45-90 minutes. Insufflated: 5-15 minutes.", - "duration": "Oral: 2-5 hours. | Insufflated: 1-1.5 hours.", - "after-effects": "Oral: 2-5 hours. | Insufflated: 1-3 hours.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ] - }, - "pretty_name": "3-MEC", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-175mg", - "Strong": "175-250mg+" - }, - "Insufflated:": { - "Insufflated": "Light", - "Common": "50-100mg", - "Strong": "100-150mg+" - } - }, - "formatted_duration": { - "Oral": "2-5", - "Insufflated": "1-1.5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "45-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "2-5", - "Insufflated": "1-3", - "_unit": "hours" - }, - "id": 105 - }, - "zopiclone": { - "name": "zopiclone", - "properties": { - "effects": "Lethargy, tiredness, a dreamlike state while awake, can induce heavy sleep.", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "dose": "Oral Threshold: 3.5mg Light: 3.5-5mg Common: 5-7.5mg Strong: 7.5-15mg Heavy: 15-22.5mg", - "onset": "15 - 30 minutes (on empty stomach)", - "duration": "3.5-9 hours", - "aliases": [ - "imovane", - "zimovane" - ], - "summary": "A nonbenzodiazepine sedative sleep aid (Z-drug), which can have hallucinogenic effects if taken while awake. Often causes users to have a metallic taste in the mouth for ~12h. Has been reported in some cases to cause certain users to black out, redose excessively and undertake dangerous activities such as driving.", - "contraindictions": "Liver disease, myasthenia gravis, severe chronic bronchitis, emphysema, sleep apnea, thyroid gland abnormalities, trimipramine, caffeine, alcohol, erythromycin, itraconazole, rifampicin, phenytoin, carbamazepine, ketoconazole, sulfaphenazole, and nefazodone", - "chemistry": "IUPAC: (RS)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate | Formula: C17H17ClN6O3 | Molecular Mass: 388.808 g/mol", - "pharmacology": "GABA-A receptor positive allosteric modulator; Benzodiazepine receptor agonist", - "pharmacokinetics": "Protein Binding: 45 - 80% | Metabolism: various cytochrome P450 liver enzymes | Excretion: respiration (~50%) and urine (7 - 10 %)", - "legal": "Australia: Prescription Only (S4) | United Kingdom: Controlled Drug (POM) | United States: Schedule IV", - "after-effects": "1-12 hours." - }, - "pretty_name": "Zopiclone", - "aliases": [ - "imovane", - "zimovane" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3.5mg", - "Light": "3.5-5mg", - "Common": "5-7.5mg", - "Strong": "7.5-15mg", - "Heavy": "15-22.5mg" - } - }, - "formatted_duration": { - "value": "3.5-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Lethargy", - "tiredness", - "a dreamlike state while awake", - "can induce heavy sleep", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Dependence potential of zopiclone studied in monkeys - http://www.ncbi.nlm.nih.gov/pubmed/6892368" - ] - }, - "id": 106 - }, - "u-47700": { - "name": "u-47700", - "properties": { - "summary": "A µ-opioid receptor agonist that is related to AH-7921. Having a very short duration.", - "duration": "Oral: 5-7 hours. | Insufflated/Plugged: 3-4 hours. | Intravenous: 1-2 hours.", - "dose": "Oral Light: 5-7.5mg Common: 7.5-15mg Strong: 15-25mg Heavy: 25+mg.", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "avoid": "All other CNS depressants", - "onset": "Oral: 15 minutes. | Insufflated/Plugged: 15 minutes | Intravenous: 0-1 minutes.", - "aliases": [ - "u47700" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-4 hours." - }, - "pretty_name": "U-47700", - "aliases": [ - "u47700" - ], - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "5-7.5mg", - "Common": "7.5-15mg", - "Strong": "15-25mg", - "Heavy": "25+mg." - } - }, - "formatted_duration": { - "Oral": "5-7", - "Insufflated/Plugged": "3-4", - "Intravenous": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15", - "Insufflated/Plugged": "15", - "Intravenous": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_U47700.shtml" - }, - "pweffects": { - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 107 - }, - "25t-4-nbome": { - "name": "25t-4-nbome", - "properties": { - "dose": "Sublingual Light: 150-300ug Common: 300-750ug Strong: 750-1200ug.", - "duration": "5-9 hours.", - "after-effects": "2-12 hours.", - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ], - "onset": "20-45 minutes.", - "aliases": [ - "25t4-nbome" - ], - "summary": "A psychedelic RC of the NBOMe class of drugs that is expected to cause hallucinations. Limited human use has been recorded on this drug and caution should be used with dosing." - }, - "pretty_name": "25T-4-NBOMe", - "aliases": [ - "25t4-nbome" - ], - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Sublingual": { - "Light": "150-300ug", - "Common": "300-750ug", - "Strong": "750-1200ug." - } - }, - "formatted_duration": { - "value": "5-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 108 - }, - "5-meo-dalt": { - "name": "5-meo-dalt", - "properties": { - "summary": "A strange drug with an unknown mechanism of action. Some psychedelic effects alongside some effects non-characteristic of psychedelics like appetite enhancement. Reported as having rapid, intense and short acting entheogenic effects.", - "dose": "Oral Threshold: 4-5mg Light: 5-12mg Common: 12-20mg Strong: 20+mg | Vaporized Light: 2-5mg Common: 5-15mg Strong: 15+mg", - "onset": "oral: 15-30 minutes. Smoked: 1-2 minutes.", - "duration": "Oral: 2-4 hours. Smoked: 20-30 minutes.", - "after-effects": "Oral: 1-2 hours. Smoked: 5-10 minutes.", - "avoid": "MAOI's.", - "aliases": [ - "5meodalt" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "5-MeO-DALT", - "aliases": [ - "5meodalt" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "4-5mg", - "Light": "5-12mg", - "Common": "12-20mg", - "Strong": "20+mg" - }, - "Vaporized": { - "Light": "2-5mg", - "Common": "5-15mg", - "Strong": "15+mg" - } - }, - "formatted_duration": { - "Oral": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "oral": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeODALT.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "Oral": "1-2", - "_unit": "hours" - }, - "id": 109 - }, - "memantine": { - "name": "memantine", - "properties": { - "summary": "An NMDA-antagonist that if used recreationally can cause to a very prolonged \"hole\" lasting up to 16+ hours.", - "onset": "30-90 minutes.", - "duration": "12-72 hours", - "dose": "Oral Low: 10-20mg Common: 20-40mg Heavy: 40-80mg+", - "categories": [ - "dissociative", - "tentative" - ], - "after-effects": "1-72 hours." - }, - "pretty_name": "Memantine", - "categories": [ - "dissociative", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Low": "10-20mg", - "Common": "20-40mg", - "Heavy": "40-80mg+" - } - }, - "formatted_duration": { - "value": "12-72", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-72", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Memantine prevents aluminum-induced cognitive deficit in rats. - https://www.ncbi.nlm.nih.gov/pubmed/21741993" - ] - }, - "id": 110 - }, - "aniracetam": { - "name": "aniracetam", - "properties": { - "summary": "An anxiolytic nootropic which modulates the AMPA receptor. Significantly more potent than racetam. May have positive effects on memory and cognition. Little recreational value. Sold in Europe as a prescription drug, but not approved by the FDA in the US.", - "dose": "Oral Common: 1500mg", - "duration": "2-4 hours.", - "categories": [ - "research-chemical", - "nootropic" - ], - "onset": "Rapid", - "bioavaiability": "Oral: 8.6-11.4% (This is due to the extensive first pass hepatic metabolism) Presumably higher when taken with fatty acids.", - "after-effects": "1-4 hours." - }, - "pretty_name": "Aniracetam", - "categories": [ - "research-chemical", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Common": "1500mg" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Rapid" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Aniracetam.shtml" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 111 - }, - "fluoxetine": { - "name": "fluoxetine", - "properties": { - "categories": [ - "ssri" - ], - "aliases": [ - "prozac", - "sarafem" - ] - }, - "pretty_name": "Fluoxetine", - "aliases": [ - "prozac", - "sarafem" - ], - "categories": [ - "ssri" - ], - "id": 112 - }, - "a-pvt": { - "name": "a-pvt", - "properties": { - "summary": "A rare stimulant drug related to a-PVP, very uncommon. Probably less potent than a-PVP, however little data exists on this compound or its effects on humans.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "onset": "Oral 10-30 minutes. | Insufflated 1-10 minutes. | Vapourized 1-2 minutes.", - "duration": "Oral 2-4 hours. | Insufflated 2-4 hours. | Vapourized 1-2 hours.", - "after-effects": "1-4 hours.", - "aliases": [ - "apvt" - ] - }, - "pretty_name": "α-PVT", - "aliases": [ - "apvt" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "2-4", - "Vapourized": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "Insufflated": "1-10", - "Vapourized": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 113 - }, - "bzp": { - "name": "bzp", - "properties": { - "onset": "30-45 minutes.", - "duration": "4-6 hours.", - "after-effects": "2-4 hours.", - "summary": "A stimulant that was sold as \"legal ecstasy\" in the late 2000s, and was one of the first drugs widely marketed as a \"research chemical.\" It has a much less favourable effect profile and has fallen out of popularity greatly since it was banned in many countries.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "dose": "Oral Light: 40-70mg Common: 70-100mg Strong: 100-130mg Heavy: 130mg+" - }, - "pretty_name": "BZP", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "40-70mg", - "Common": "70-100mg", - "Strong": "100-130mg", - "Heavy": "130mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 114 - }, - "2c-ip": { - "name": "2c-ip", - "properties": { - "onset": "45-90 minutes.", - "duration": "12-16 hours.", - "after-effects": "4-8 hours.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "summary": "Isopropyl analog (branched analog) of 2C-P with a slightly shorter duration and lower potency.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "test-kits": "Marquis: Orange > Red. | Mecke: Yellow > Brown. | Mandelin: Green. | Ehrlich: No colour change." - }, - "pretty_name": "2C-IP", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "none": { - "Threshold": "5mg", - "Light": "5-15mg", - "Common": "15-30mg", - "Heavy": "30-45mg" - } - }, - "formatted_duration": { - "value": "12-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "4-8", - "_unit": "hours" - }, - "id": 115 - }, - "doc": { - "name": "doc", - "properties": { - "summary": "A potent stimulating psychedelic with a long action, a phenethylamine and substituted amphetamine. Sometimes sold as LSD but also enjoyed on its own merits by many. Usually sold on blotters slightly larger than those LSD is found on, but can also be bought in powder form.", - "dose": "Oral Light: 1-1.5mg Common: 1.5-2mg Strong: 2-4mg Heavy: 4mg+", - "onset": "30-150 minutes (Highly dependant on dose)", - "duration": "10-20 hours. (Dependant on dose)", - "after-effects": "6-12 hours.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "common" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "DOC", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "1-1.5mg", - "Common": "1.5-2mg", - "Strong": "2-4mg", - "Heavy": "4mg+" - } - }, - "formatted_duration": { - "value": "10-20", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-150", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DOC.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal064.shtml" - }, - "formatted_aftereffects": { - "value": "6-12", - "_unit": "hours" - }, - "id": 116 - }, - "4-ho-mpmi": { - "name": "4-ho-mpmi", - "properties": { - "summary": "A rare tryptamine derivative first synthesised by David Nichols. This drug, also known as lucigenol, has rarely been documented outside the lab. It is known to be a psychedelic similar to other psychoactive tryptamines, with a potency similar to DOI, but little else is known.", - "duration": "6-8 hours.", - "dose": "Oral Threshold: 500-750ug. Light: 750ug-1mg Common: 1-2mg. | Note, this substance has never been reported on past 2mg's. Use you're judgement; It's near eqipotent to DOI.", - "aliases": [ - "lucigenol" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "onset": "15-60 minutes." - }, - "pretty_name": "4-HO-MPMI", - "aliases": [ - "lucigenol" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "500-750ug.", - "Light": "750ug-1mg", - "Common": "1-2mg." - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "dose_note": " Note, this substance has never been reported on past 2mg's. Use you're judgement; It's near eqipotent to DOI.", - "id": 117 - }, - "dpt": { - "name": "dpt", - "properties": { - "dose": "Oral Light: 75-125mg Common: 125-200mg Strong: 200-250mg | Insufflated Light: 20-50 Common: 50-100mg Strong: 100-150mg | IM Threshold: 5-10mg Light: 10-35mg Common: 35-60mg Strong: 60-100mg | Smoked Threshold: 5-10mg Light: 15-30mg Common: 30-50mg Strong: 50-100mg", - "onset": "Oral: 20-60 minutes | Insufflated: 5-20 minutes | IM: 2-10 minutes | Smoked: 0-1 minutes", - "duration": "Oral: 2-4 hours | Insufflated: 3-4 hours. | IM: 3-4 hours. | Smoked: 0.5-1.5 hours.", - "after-effects": "Oral: 2-3 hours | Insufflated: 3-4 hours | IM: 2-4 hours | Smoked: 2-4 hours", - "effects": "A psychedelic tryptamine with \"a wide range of effects at any particular dose depending on the individual\"", - "aliases": [ - "dipropyltryptamine" - ], - "summary": "N,N-Dipropyltryptamine, a psychedelic tryptamine compound and lesser-known analogue of DMT, with similar psychedelic effects. Like DMT it is a partial serotonin receptor agonist.", - "categories": [ - "psychedelic", - "research-chemical" - ] - }, - "pretty_name": "DPT", - "aliases": [ - "dipropyltryptamine" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "75-125mg", - "Common": "125-200mg", - "Strong": "200-250mg" - }, - "Insufflated": { - "Light": "20-50", - "Common": "50-100mg", - "Strong": "100-150mg" - }, - "IM": { - "Threshold": "5-10mg", - "Light": "10-35mg", - "Common": "35-60mg", - "Strong": "60-100mg" - }, - "Smoked": { - "Threshold": "5-10mg", - "Light": "15-30mg", - "Common": "30-50mg", - "Strong": "50-100mg" - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "3-4", - "IM": "3-4", - "Smoked": "0.5-1.5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-60", - "Insufflated": "5-20", - "IM": "2-10", - "Smoked": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "A psychedelic tryptamine with \"a wide range of effects at any particular dose depending on the individual\"" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal09.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour replacement": "https://psychonautwiki.org/wiki/Colour_replacement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Machinescapes": "https://psychonautwiki.org/wiki/Machinescapes", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Recursion": "https://psychonautwiki.org/wiki/Recursion", - "Rejuvenation": "https://psychonautwiki.org/wiki/Rejuvenation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "Oral": "2-3", - "Insufflated": "3-4", - "IM": "2-4", - "Smoked": "2-4", - "_unit": "hours" - }, - "id": 118 - }, - "dexedrine": { - "name": "dexedrine", - "properties": { - "summary": "A highly abusable stimulant. It is rarely prescribed in the US to treat ADHD, and is very similar in effects to Adderall, as its main ingredient is 75% of what adderall is.", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "dose": "Light: 5-10mg Common: 10-20mg Strong: 20-30mg.", - "onset": "20-60 minutes.", - "duration": "3-6 hours.", - "after-effects": "2-24 hours.", - "avoid": "Other stimulants.", - "aliases": [ - "dextroamphetamine", - "dexamfetamine" - ] - }, - "pretty_name": "Dexedrine", - "aliases": [ - "dextroamphetamine", - "dexamfetamine" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-30mg." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "pregnancy category C according to the FDA - http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017078s042lbl.pdf" - ] - }, - "id": 119 - }, - "methoxypiperamide": { - "name": "methoxypiperamide", - "properties": { - "summary": "Drug of the Piperazine class. The 4-Methoxy-α-keto analogue of Methylbenzylpiperazine. Seemingly inactive on its own. Was sold in tandem with Mephtetramine.", - "categories": [ - "inactive", - "research-chemical" - ] - }, - "pretty_name": "Methoxypiperamide", - "categories": [ - "inactive", - "research-chemical" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 120 - }, - "buprenorphine": { - "name": "buprenorphine", - "properties": { - "summary": "A semi-synthetic opioid analgesic also known as subutex. Often administered as Butrans patches, or in combination with Naloxone as Suboxone, a heroin replacement therapy drug. Will cause withdrawals if you have an opioid tolerance and don't wait long enough (typically around 48 hours) before taking this.", - "duration": "Low Dose: 8-12 hours High Dose: 24-72 hours", - "onset": "60-90 minutes", - "bioavailability": "Oral 22% | Sublingual 30% | Intramuscular 90-100%", - "dose": "\u000303Light\u0003: 1-2mg \u000308Common\u0003: 3-6mg \u000304Strong\u0003: 6-8mg \u000305Heavy\u0003: 8mg+ | \u0002WARNING\u0003: These doses are for tolerant users, new users can require as little as 0.1mg.", - "aliases": [ - "suboxone", - "subs", - "bupe" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-16 hours." - }, - "pretty_name": "Buprenorphine", - "aliases": [ - "suboxone", - "subs", - "bupe" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "\u000303Light\u0003:": {}, - "\u0002WARNING\u0003:": {} - }, - "formatted_duration": { - "Low": "Dose", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "dose_note": " NOTE: The ceiling dose for Buprenorphine is usually between 16mg and 32mg, anything above this will not produce any increase in effects. Also, after dosing 4mg your opioid receptors are completely covered.", - "sources": { - "_general": [ - "https://www.ncbi.nlm.nih.gov/pubmed/10928310-Effects of buprenorphine versus buprenorphine/naloxone tablets in non-dependent opioid abusers." - ] - }, - "id": 121 - }, - "u-49900": { - "name": "u-49900", - "properties": { - "summary": "A substance that is an analogue of U-47700, yet doesn't share much with it. If you are interested in trying it, I recommend reading this. https://www.reddit.com/r/researchchemicals/comments/5gbo3e/u49900_experiment_and_warning/", - "categories": [ - "opioid", - "dissociative", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "U-49900", - "categories": [ - "opioid", - "dissociative", - "research-chemical", - "tentative" - ], - "id": 122 - }, - "mdpa": { - "name": "mdpa", - "properties": { - "summary": "An obscure substituted methylenedioxyphenethylamine with practically no history of human use. Its pharmacological profile is largely unknown, but potentially exhibits similar properties to other MDxx compounds. May be a monoamine releaser, reuptake inhibitor or both.", - "duration": "2-4 hours", - "dose": "Oral Light: 75-125mg Common: 125-175mg Strong: 175-250mg Heavy: 250+mg.", - "categories": [ - "empathogen", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "methylenedioxyphenylacetamide" - ], - "onset": "15-45 minutes." - }, - "pretty_name": "MDPA", - "aliases": [ - "methylenedioxyphenylacetamide" - ], - "categories": [ - "empathogen", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "75-125mg", - "Common": "125-175mg", - "Strong": "175-250mg", - "Heavy": "250+mg." - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "id": 123 - }, - "tetrazepam": { - "name": "tetrazepam", - "properties": { - "summary": "A benzodiazepine that has most of the properties of more common benzodiazepines. Yet was taken off the market in 2013. Has been noted to be more euphoric than most others.", - "onset": "Oral: 15-35 minutes.", - "duration": "Oral: 6-10 hours.", - "dose": "Light: 25-50mg Common: 50-100mg Strong: 100-200mg+", - "after-effects": "1-12 hours.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "avoid": "All other CNS depressants." - }, - "pretty_name": "Tetrazepam", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50mg", - "Common": "50-100mg", - "Strong": "100-200mg+" - } - }, - "formatted_duration": { - "Oral": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-35", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 124 - }, - "25h-nbome": { - "name": "25h-nbome", - "properties": { - "summary": "A rare psychedelic stimulant and bomamine. A derivative of 2C-H, but many times more potent. Likely to have hallucinogenic, stimulant and vasoconstrictive properties which may be dangerous at high doses. A heavy body load is to be expected.", - "duration": "3-5 hours.", - "onset": "30-90 minutes.", - "dose": "NOTE: This chemical has an extremely odd response curve. Some get effects from 2mg while other don't until around the 7mg range. If you plan to use this chemical start with a low dose and work your way up.", - "after-effects": "2-3 hours.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "25h", - "25-h-nbome" - ], - "test-kits": "Marquis: Light Brown > Brown. | Mecke: Yellow > Green/Brown. | Mandelin: Green/Brown > Orange. | Simon's: Orange > Black." - }, - "pretty_name": "25H-NBOMe", - "aliases": [ - "25h", - "25-h-nbome" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "NOTE": "This" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "2-3", - "_unit": "hours" - }, - "id": 125 - }, - "eflea": { - "name": "eflea", - "properties": { - "summary": "Prodrug for EDMA. May be inactive.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "inactive" - ] - }, - "pretty_name": "EFLEA", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "inactive" - ], - "id": 126 - }, - "mexedrone": { - "name": "mexedrone", - "properties": { - "summary": "Mexedrone is a stimulant drug of the cathinone class. It alters the reuptake of serotonin, dopamine, and norepinephrine to cause euphoria, and is similar in effects to mephedrone. It is considered a designer drug and is in a legally grey area globally.", - "categories": [ - "empathogen", - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "dose": "Oral Light: 75-150mg Common: 150-200 Strong: 200-300mg+ | Insufflated Light: 50-80mg Common: 80-120mg Strong: 120-200mg+", - "duration": "1-3 hours.", - "after-effects": "Oral: 2-6 | Insufflated: 1-4 hours.", - "warning": "Caution: not much is known about how mexedrone affects the body as it is relatively new, be cautious with doses and how you use it.", - "onset": "Oral: 30-60 minutes. | Insufflated: 3-10 minutes.", - "aliases": [ - "4-mmeoc" - ] - }, - "pretty_name": "Mexedrone", - "aliases": [ - "4-mmeoc" - ], - "categories": [ - "empathogen", - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "75-150mg", - "Common": "150-200", - "Strong": "200-300mg+" - }, - "Insufflated": { - "Light": "50-80mg", - "Common": "80-120mg", - "Strong": "120-200mg+" - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60", - "Insufflated": "3-10", - "_unit": "minutes" - }, - "pweffects": { - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Vibrating vision": "https://psychonautwiki.org/wiki/Vibrating_vision" - }, - "formatted_aftereffects": { - "Oral": "2-6", - "Insufflated": "1-4", - "_unit": "hours" - }, - "id": 127 - }, - "dob": { - "name": "dob", - "properties": { - "summary": "DOB is a relatively uncommon synthetic psychedelic. It is best known for its very low doses and long duration. Historically it has rarely been taken deliberately, but in place of LSD, however it has recently found its own place in the research chemical scene.", - "onset": "30-120 minutes.", - "duration": "8-24 hours.", - "dose": "Oral Threshold: 500ug Light: 750ug Common: 750-1100ug Heavy: 1100-1500ug Dangerous: 3000ug", - "after-effects": "2-12 hours", - "marquis": "Olive Green - Yellow", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "DOB", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "500ug", - "Light": "750ug", - "Common": "750-1100ug", - "Heavy": "1100-1500ug", - "Dangerous": "3000ug" - } - }, - "formatted_duration": { - "value": "8-24", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DOB.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal062.shtml" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 128 - }, - "pemoline": { - "name": "pemoline", - "properties": { - "summary": "A stimulant of the 4-oxazolidinone class. Was used as a medication for ADHD and Narcolepsy, yet was pulled from most markets due to liver failures among children.", - "dose": "Low: 10-20mg Common: 20-40mg Strong: 40-80mg.", - "onset": "15-30 minutes.", - "duration": "4-6 hours.", - "after-effects": "1-6 hours.", - "categories": [ - "stimulant", - "habit-forming" - ] - }, - "pretty_name": "Pemoline", - "categories": [ - "stimulant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Low": "10-20mg", - "Common": "20-40mg", - "Strong": "40-80mg." - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 129 - }, - "4-ho-met": { - "name": "4-ho-met", - "properties": { - "summary": "A lesser known psychedelic tryptamine. Functional analogue of Psilocin. Very poorly soluble in water and alcohol.", - "effects": "A trip similar to mushrooms, hallucination and general shift in consciousness.", - "onset": "Oral: 5-60 minutes | Insufflated: 5-25 minutes | Intravenous: 2-10 minutes", - "duration": "3-7 hours Intravenous 2-4 Hours", - "after-effects": "2-8 hours.", - "detection": "Not known to be tested for in any standard drug tests", - "dose": "Oral Light: 10mg Common: 10-15mg Strong: 20mg+ | Intravenous Light: 5mg Common: 10-15mg Strong: 20mg+", - "aliases": [ - "4homet", - "homet", - "metocin", - "ethocin" - ], - "categories": [ - "psychedelic", - "research-chemical", - "common" - ] - }, - "pretty_name": "4-HO-MET", - "aliases": [ - "4homet", - "homet", - "metocin", - "ethocin" - ], - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "10mg", - "Common": "10-15mg", - "Strong": "20mg+" - }, - "Intravenous": { - "Light": "5mg", - "Common": "10-15mg", - "Strong": "20mg+" - } - }, - "formatted_duration": { - "value": "3-7", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "5-60", - "Insufflated": "5-25", - "Intravenous": "2-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "A trip similar to mushrooms", - "hallucination and general shift in consciousness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4HOMET.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal21.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depth perception distortions": "https://psychonautwiki.org/wiki/Depth_perception_distortions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "2-8", - "_unit": "hours" - }, - "id": 130 - }, - "methamnetamine": { - "name": "methamnetamine", - "properties": { - "onset": "10-30 minutes.", - "duration": "3-6 hours.", - "dose": "Oral Light: 60-80mg Common: 80-120mg Strong: 120-150mg Heavy: 150mg+", - "aliases": [ - "methylnaphetamine", - "mnt", - "n-methyl-pal-287" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "tentative", - "empathogen", - "habit-forming" - ], - "summary": "A selective serotonin releaser, which also shows some light psychedelic activity. Almost always taken with a stimulant, to cause euphoric effects.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Methamnetamine", - "aliases": [ - "methylnaphetamine", - "mnt", - "n-methyl-pal-287" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "tentative", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "60-80mg", - "Common": "80-120mg", - "Strong": "120-150mg", - "Heavy": "150mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 131 - }, - "centrophenoxine": { - "name": "centrophenoxine", - "properties": { - "summary": "Cholinergic compound with a DMAE compotent. Is thought to help in reversing some signs of aging. Naturally found substance, most notably in fish.", - "aliases": [ - "lucidril", - "meclofenoxate" - ], - "dose": "250mg 1-6x a day.", - "duration": "4-8 hours.", - "categories": [ - "nootropic", - "tentative", - "stimulant" - ] - }, - "pretty_name": "Centrophenoxine", - "aliases": [ - "lucidril", - "meclofenoxate" - ], - "categories": [ - "nootropic", - "tentative", - "stimulant" - ], - "formatted_dose": { - "250mg": {} - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "id": 132 - }, - "4-cma": { - "name": "4-cma", - "properties": { - "summary": "The stimulant that is the N-Methyl Derivative and prodrug of the neurotoxic para-Chloroamphetamine.", - "warning": "Prodrug of the Neurotoxic para-Chloroamphetamine.", - "categories": [ - "research-chemical" - ] - }, - "pretty_name": "4-CMA", - "categories": [ - "research-chemical" - ], - "id": 133 - }, - "ketobemidone": { - "name": "ketobemidone", - "properties": { - "onset": "Oral: 45-60 minutes. Insufflated: 5-15 minutes. Plugged: 15-30 minutes.", - "summary": "An opioid analgesic drug that also acts as an NDMA antagonist. Found to be as potent as morphine in physical side effects, and has high potential for addiction like all opioids do. Overdose may lead to respiratory depression/death. Do not mix with CNS depressants or stimulants. Caution should be used for asthmatic users.", - "duration": "Oral: 4-8 hours Insufflated: 2-4 hours. Plugged: 5-10 hours. Intravenious: 2-4 hours.", - "avoid": "All other CNS depressants.", - "aliases": [ - "kbd" - ], - "dose": "Oral Light: 5mg Common: 5-10mg Strong: 10-15mg.", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "Bioavailability": "Oral: 34% Insufflated ~30-40% Plugged: 44% Intravenous: 99%+", - "half-life": "2.25-2.45 Hours.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "bioavailability": "Oral 34% +/- 10% | Rectal 44% +/- 9%", - "after-effects": "1-8 hours." - }, - "pretty_name": "Ketobemidone", - "aliases": [ - "kbd" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "5mg", - "Common": "5-10mg", - "Strong": "10-15mg." - } - }, - "formatted_duration": { - "Oral": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "45-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 134 - }, - "1cp-lsd": { - "name": "1cp-lsd", - "properties": { - "summary": "1cP-LSD (1-cyclopropionyl-lysergic acid diethylamide) is a novel lysergamide with little to no history of use. It is said to be a less pushy and shorter lasting version of LSD. Described as having a more gradual onset than 1P-LSD, with a less visual more meditative headspace when compared with LSD.*NOTE: This is a very new research chemical - take all info with a grain of salt.*", - "duration": "8-10 hours", - "onset": "30-90 minutes", - "after-effects": "6-24 hours", - "dose": "Oral Light: 25-50ug Common: 50-100ug Strong: 100-200ug", - "aliases": [ - "1cplsd", - "curie", - "1cp" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "1CP-LSD", - "aliases": [ - "1cplsd", - "curie", - "1cp" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50ug", - "Common": "50-100ug", - "Strong": "100-200ug" - } - }, - "formatted_duration": { - "value": "8-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "id": 135 - }, - "dopr": { - "name": "dopr", - "properties": { - "summary": "A rare psychedelic amphetamine of the same class as DOM. This is a powerful and potent psychedelic with all the effects you would expect from an amphetamine. Described by Shulgin as a 'heavy duty psychedelic'. Analogue of 2C-P.", - "duration": "18-30 hours", - "onset": "90-240 minutes", - "dose": "Threshold: 1.25mg Light: 2.5mg Common: 2.5-3.5mg Heavy: 3.5-5mg. ", - "avoid": "Double dosing, as it is a DOx compound, and any other amphetamine related drug.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-24 hours." - }, - "pretty_name": "DOPR", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "1.25mg", - "Light": "2.5mg", - "Common": "2.5-3.5mg", - "Heavy": "3.5-5mg." - } - }, - "formatted_duration": { - "value": "18-30", - "_unit": "hours" - }, - "formatted_onset": { - "value": "90-240", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DOPR.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal071.shtml" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 136 - }, - "chloroform": { - "name": "chloroform", - "properties": { - "onset": "Rapid.", - "duration": "Short.", - "summary": "A naturally occurring organic compound once used as an anaesthetic. Has practically disappeared in this usage due to numerous harmful effects including danger of sudden death through cardiac arrhythmia. Has been implicated in numerous murders. Highly unsafe.", - "avoid": "Avoid CNS depressants and smoking if you do decide to take this chemical.", - "obtain": "Air.", - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "Chloroform", - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "formatted_duration": { - "value": "Short." - }, - "formatted_onset": { - "value": "Rapid." - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Chloroform.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 137 - }, - "pinazepam": { - "name": "pinazepam", - "properties": { - "summary": "Benzodiazepine that is solely an anxiolytic drug that lacks the hypnotic and motor impairment that most benzodiazepines do. The main metabolite of this is Nordazepam and to a lesser effect Oxazepam, which is where it gets most of its effects", - "dose": "Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg+", - "onset": "15-90 minutes.", - "avoid": "All CNS depressants.", - "after-effects": "2-10 hours.", - "duration": "6-16 hours.", - "aliases": [ - "domar" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Pinazepam", - "aliases": [ - "domar" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "value": "6-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-10", - "_unit": "hours" - }, - "id": 138 - }, - "bk-ivp": { - "name": "bk-ivp", - "properties": { - "summary": "The beta-ketone analogue of IVP, this is a rare RC stimulant in the same family as MDPV. Little is known but effects are probably similar to MDPV or more generally amphetamine or high dose caffeine.", - "onset": "Rapid.", - "duration": "1-3 hours.", - "dose": "Light: 60-100mg Common: 100-150mg Strong: 150-200mg+", - "categories": [ - "stimulant", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "βk-IVP", - "categories": [ - "stimulant", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "60-100mg", - "Common": "100-150mg", - "Strong": "150-200mg+" - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Rapid." - }, - "id": 139 - }, - "oxycodone": { - "name": "oxycodone", - "properties": { - "dose": "Oral Light: 2.5-10mg Common: 10-25mg Strong: 25-40mg | Insufflated Light: 2.5-7.5mg Common: 7.5-15mg Strong: 15-25mg", - "onset": "Oral_IR: 20 minutes | Oral_ER: 40 minutes | Insufflated: 2-5 minutes | IV: 0-1 minutes", - "potentiators": "Avoid grapefruit juice, alcohol, and diphenhydramine. These products may react negatively and cause an overdose. Also do not consume more than 4g APAP (acetaminophen) in a day.", - "detection": "3-5 days for minimal use, 5-8 for regular use.", - "summary": "A semisynthetic opioid analgesic developed in 1917, prescribed primarily for pain management. It has become extremely popular as a recreational drug in some areas, and carries a high potential for addiction. Reported as being a little more 'stimulating' than other opioids.", - "aliases": [ - "oxy", - "oxycontin", - "percocet", - "oxynorm" - ], - "marquis": "Pale violet", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "duration": "Oral_IR: 4-6 hours | Oral_ER: 6-8 hours. | Insufflated: 3-5 hours. | IV: 3-5 hours.", - "bioavailability": "Oral 60-87% | Insufflated 55-70%", - "half-life": "2-4 hours", - "after-effects": "1-24 hours.", - "effects": "Pain relief, Respiratory depression, Sedation, Constipation, Cough suppression, Decreased libido, Difficulty urinating, Itchiness, Nausea, Pupil constriction, Stomach cramps, Appetite suppression, Euphoria, Anxiety suppression, Dream potentiation." - }, - "pretty_name": "Oxycodone", - "aliases": [ - "oxy", - "oxycontin", - "percocet", - "oxynorm" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-10mg", - "Common": "10-25mg", - "Strong": "25-40mg" - }, - "Insufflated": { - "Light": "2.5-7.5mg", - "Common": "7.5-15mg", - "Strong": "15-25mg" - } - }, - "formatted_duration": { - "Oral_IR": "4-6", - "Oral_ER": "6-8", - "Insufflated": "3-5", - "IV": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral_IR": "20", - "Oral_ER": "40", - "Insufflated": "2-5", - "IV": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Pain relief", - "Respiratory depression", - "Sedation", - "Constipation", - "Cough suppression", - "Decreased libido", - "Difficulty urinating", - "Itchiness", - "Nausea", - "Pupil constriction", - "Stomach cramps", - "Appetite suppression", - "Euphoria", - "Anxiety suppression", - "Dream potentiation", - "" - ], - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Stomach cramps": "https://psychonautwiki.org/wiki/Stomach_cramps" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Controlled-release oxycodone-induced seizures. - http://www.ncbi.nlm.nih.gov/pubmed/16368452", - "Grapefruit juice enhances the exposure to oral oxycodone. - http://www.ncbi.nlm.nih.gov/pubmed/20406214", - "Oxycodone/paracetamol: a low-dose synergic combination useful in different types of pain. - http://www.ncbi.nlm.nih.gov/pubmed/20670044", - "Pharmacokinetics and pharmacodynamics of oxycodone when given intravenously and rectally to adult patients with cancer pain. - http://www.ncbi.nlm.nih.gov/pubmed/7818116", - "Differential effects of food on the bioavailability of controlled-release oxycodone tablets and immediate-release oxycodone solution. - http://www.ncbi.nlm.nih.gov/pubmed/8901078", - "Oxycodone is found to suppress sodium currents in the thalamic regions of the brain at high doses and is an effect that is independent of the MOR/u-opioid recepter and therefore this mechanism is not blocked by the use of naloxone - http://www.sciencedirect.com/science/article/pii/S0304394009001268", - "Oxycodone is found to have longer lasting more efficient effects on pain due to neuropathy because of having GABA-B agonist properties -http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091297", - "Oxycodone when paired with an ultra low dose of naltrexone, an opioid antagonist, oxycodone has a longer duration of pain relief - http://www.sciencedirect.com/science/article/pii/S1526590005004128", - "Oxycodone has been found to be an effective treatment for restless leg syndrome - http://europepmc.org/abstract/med/8341893", - "Pharmacokinetics of oxycodone done orally and intramuscularly http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.1992.tb04090.x/abstract" - ] - }, - "id": 140 - }, - "nifoxipam": { - "name": "nifoxipam", - "properties": { - "summary": "An uncommon and relatively new RC benzodiazepine, and metabolite of the hypnotic benzodiazepine flunitrazepam. Little information about the pharmacological properties of this drug exists. Likely to be a strong sedative and hypnotic.", - "dose": "Oral Light: 250ug-500ug. Common: 500ug-1000ug Heavy: 1000ug-2000ug+ | NOTE: Higher doses will increase the likelihood of blacking out", - "onset": "10-75 minutes.", - "duration": "10-18 hours. ", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-24 hours." - }, - "pretty_name": "Nifoxipam", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "250ug-500ug.", - "Common": "500ug-1000ug", - "Heavy": "1000ug-2000ug+" - } - }, - "formatted_duration": { - "value": "10-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-75", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Higher doses will increase the likelihood of blacking out", - "id": 141 - }, - "alcohol": { - "name": "alcohol", - "properties": { - "detection": "12 hrs blood, 6-12 hrs saliva, 6-24 hrs urine", - "duration": "1.5-3 hours", - "onset": "15-30 minutes", - "effects": "relaxation, mood lift, happiness, sociability, lowered inhibitions, analgesia, slurred speech, flushed skin, drowsiness, tolerance, euphoria, amnesia", - "summary": "Alcohol is a CNS depressant that acts through the GABAₐ receptor, and is one of the most common strong psychoactives used by humans. It has a long history of use and its intoxicating effects are well-studied and documented. It remains legal in most parts of the world.", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "after-effects": "6-48 hours", - "dose": "Oral Light: 1-2units Common: 2-4units Heavy: 5-6units | NOTE: Alcohol consumption should be spread out over a few hours and ideally separated by water breaks. Check the label on alcohol for unit content", - "aliases": [ - "etoh", - "beer", - "ethanol", - "booze", - "hooch" - ] - }, - "pretty_name": "Alcohol", - "aliases": [ - "etoh", - "beer", - "ethanol", - "booze", - "hooch" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "1-2units", - "Common": "2-4units", - "Heavy": "5-6units" - } - }, - "formatted_duration": { - "value": "1.5-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "relaxation", - "mood lift", - "happiness", - "sociability", - "lowered inhibitions", - "analgesia", - "slurred speech", - "flushed skin", - "drowsiness", - "tolerance", - "euphoria", - "amnesia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Alcohol.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Creativity suppression": "https://psychonautwiki.org/wiki/Creativity_suppression", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Ego inflation": "https://psychonautwiki.org/wiki/Ego_inflation", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Temporary erectile dysfunction": "https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization" - }, - "formatted_aftereffects": { - "value": "6-48", - "_unit": "hours" - }, - "dose_note": " NOTE: Alcohol consumption should be spread out over a few hours and ideally separated by water breaks. Check the label on alcohol for unit content", - "sources": { - "_general": [ - "Alcohol and benzodiazepines in fatal poisonings. - https://www.ncbi.nlm.nih.gov/pubmed/12170103", - "Drinking while pregnant creates and strengthens many risks associated with childbirth. It will also increase the chances of premature labour, which can be incredibly dangerous for both the baby and mother. -" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Decrease" - }, - "lsd": { - "status": "Low Risk & Decrease" - }, - "dmt": { - "status": "Low Risk & Decrease" - }, - "mescaline": { - "status": "Low Risk & Decrease" - }, - "dox": { - "status": "Low Risk & Decrease", - "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk." - }, - "nbomes": { - "status": "Low Risk & Decrease" - }, - "2c-x": { - "status": "Low Risk & Decrease" - }, - "2c-t-x": { - "status": "Low Risk & Decrease", - "note": "Both these classes of compound can interact unpredictably. Caution should be exercised." - }, - "amt": { - "status": "Caution", - "note": "aMT has a broad mechanism of action in the brain and so does alcohol so the combination can be unpredictable" - }, - "5-meo-xxt": { - "status": "Low Risk & Decrease" - }, - "cannabis": { - "status": "Low Risk & Synergy", - "note": "In excess, this combination can cause nausea." - }, - "ketamine": { - "status": "Dangerous", - "note": "Both substances cause ataxia and bring a very high risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position." - }, - "mxe": { - "status": "Dangerous", - "note": "There is a high risk of memory loss, vomiting and severe ataxia from this combination." - }, - "dxm": { - "status": "Dangerous", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Additionally CNS depression can lead to difficulty breathing. Avoid on anything higher than 1st plateau." - }, - "pcp": { - "status": "Unsafe", - "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner." - }, - "nitrous": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely." - }, - "amphetamines": { - "status": "Caution", - "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol and the stimulant less. Extended release formulations may severely impede sleep, further worsening the hangover." - }, - "mdma": { - "status": "Caution", - "note": "Both MDMA and alcohol cause dehydration. Approach this combination with caution, moderation and sufficient hydration. More than a small amount of alcohol will dull the euphoria of MDMA" - }, - "cocaine": { - "status": "Unsafe", - "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol less. Cocaine is potentiated somewhat by alcohol because of the formation of cocaethylene." - }, - "caffeine": { - "status": "Low Risk & No Synergy" - }, - "ghb/gbl": { - "status": "Dangerous", - "note": "Even in very low doses this combination rapidly leads to memory loss, severe ataxia and unconsciousness. There is a high risk of vomit aspiration while unconscious." - }, - "opioids": { - "status": "Dangerous", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely" - }, - "tramadol": { - "status": "Dangerous", - "note": "Heavy CNS depressants, risk of seizures. Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely." - }, - "benzodiazepines": { - "status": "Dangerous", - "note": "Ethanol ingestion may potentiate the CNS effects of many benzodiazepines. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Blacking out and memory loss is almost certain." - }, - "benzos": { - "status": "Dangerous", - "note": "Ethanol ingestion may potentiate the CNS effects of many benzodiazepines. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Blacking out and memory loss is almost certain." - }, - "maois": { - "status": "Unsafe", - "note": "Tyramine found in many alcoholic beverages can have dangerous reactions with MAOIs, causing an increase in blood pressure." - }, - "ssris": { - "status": "Caution", - "note": "Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills." - } - }, - "id": 142 - }, - "5f-akb48": { - "name": "5f-akb48", - "properties": { - "summary": "A synthetic cannabanoid that is a Indazole. Produces subjective effects somehwat similar to that of Cannabis, yet with a very short duration. Analogue of STS-135, in which the core indole structure is subbed with an indazole base.", - "dose": "Vapourized Threshold: 500ug Light: 500-1000ug Strong: 1000-2500ug.", - "duration": "Vapourized: 30-60 minutes.", - "after-effects": "Vapourized: 15-45 minutes.", - "onset": "Vapourized: 5-30 seconds.", - "aliases": [ - "5f-apinaca", - "5fapinaca", - "5fakb48" - ], - "categories": [ - "research-chemical", - "tentative", - "habit-forming" - ] - }, - "pretty_name": "5F-AKB48", - "aliases": [ - "5f-apinaca", - "5fapinaca", - "5fakb48" - ], - "categories": [ - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Vapourized": { - "Threshold": "500ug", - "Light": "500-1000ug", - "Strong": "1000-2500ug." - } - }, - "formatted_duration": { - "Vapourized": "30-60", - "_unit": "minutes" - }, - "formatted_onset": { - "Vapourized": "5-30" - }, - "formatted_aftereffects": { - "Vapourized": "15-45", - "_unit": "minutes" - }, - "id": 143 - }, - "glutethimide": { - "name": "glutethimide", - "properties": { - "summary": "Is a hypnotic sedative that was introduced in 1954, as a \"safe\" alternative to barbiturates to treat insomnia. Anecdotally long term use has had effects similar to withdrawal, while still on a stable dose of the drug.", - "dose": "Light: 250mg Common: 500mg Strong: 750mg+", - "onset": "30-45 minutes.", - "duration": "2-8 hours.", - "after-effects": "1-12 hours.", - "avoid": "All other CNS depressants.", - "aliases": [ - "doriden", - "elrodorm", - "noxyron", - "glimid" - ], - "categories": [ - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Glutethimide", - "aliases": [ - "doriden", - "elrodorm", - "noxyron", - "glimid" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "250mg", - "Common": "500mg", - "Strong": "750mg+" - } - }, - "formatted_duration": { - "value": "2-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 144 - }, - "diclazepam": { - "name": "diclazepam", - "properties": { - "dose": "Light: 0.25-1mg Common: 1-2mg's Strong: 2mg+", - "summary": "A benzodiazepine drug and analogue of diazepam first synthesised by Leo Sternbach at Hoffman-LaRoche in 1960, it has become prominent as an RC benzodiazepine on the grey market in recent years, particularly with the decline in etizolam availability. A sedative and hypnotic it is of intermediate to long half life with similar effects to diazepam, though 10x more potent.", - "onset": "15-90 minutes.", - "duration": "8-12 hours (~42 hour half-life)", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-24 hours.", - "dose_to_diazepam": "Diclazepam - 1mg ~=10mg Diazepam." - }, - "pretty_name": "Diclazepam", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.25-1mg", - "Common": "1-2mg", - "Strong": "2mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Diclazepam.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 145 - }, - "3-meo-pcpy": { - "name": "3-meo-pcpy", - "properties": { - "onset": "Oral: 15-45 minutes. Insufflated: 5-20 minutes.", - "duration": "Oral: 3-5 hours. Insufflated: 2-4 hours.", - "dose": "Oral Light: 2-4mg Common: 4-8mg Strong: 8-15mg+ | Insufflated Light: 1-3mg Common: 3-6mg Strong: 6-10mg+", - "avoid": "All other CNS depressants.", - "summary": "3-Methoxy analogue of Rolicyclidine (PCPy) less opioid effects than Phenylcyclidine (PCP) Yet still prominent.", - "categories": [ - "dissociative", - "habit-forming", - "tentative", - "research-chemical" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "3-MeO-PCPY", - "categories": [ - "dissociative", - "habit-forming", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "2-4mg", - "Common": "4-8mg", - "Strong": "8-15mg+" - }, - "Insufflated": { - "Light": "1-3mg", - "Common": "3-6mg", - "Strong": "6-10mg+" - } - }, - "formatted_duration": { - "Oral": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 146 - }, - "methoxphenidine": { - "name": "methoxphenidine", - "properties": { - "summary": "A dissociative from the diarylethylamine class, a more potent analogue of diphenidine. Known to be unpredictable, and can cause blackouts.", - "categories": [ - "dissociative", - "research-chemical", - "tentative", - "habit-forming" - ], - "after-effects": "1-3 hours, but all the time in the world young padawan.", - "onset": "30-60 minutes.", - "aliases": [ - "2-meo-diphenidine", - "methoxyphenidine", - "2-mxp", - "mxp" - ], - "duration": "6-8 hours", - "dose": "Threshold: 30-50mg Light: 50-75mg Common: 75-120mg Strong: 120-150mg+" - }, - "pretty_name": "Methoxphenidine", - "aliases": [ - "2-meo-diphenidine", - "methoxyphenidine", - "2-mxp", - "mxp" - ], - "categories": [ - "dissociative", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "30-50mg", - "Light": "50-75mg", - "Common": "75-120mg", - "Strong": "120-150mg+" - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methoxphenidine.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection" - }, - "formatted_aftereffects": { - "value": "1-3", - "_unit": "hours" - }, - "id": 147 - }, - "isoproscaline": { - "name": "isoproscaline", - "properties": { - "summary": "A analogue of mescaline, and more closely related to proscaline.", - "duration": "10-20 hours", - "dose": "Oral Threshold: 30mg Light: 40-50mg Common: 50-60mg Strong: 60-80mg+", - "onset": "60-180 minutes.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "aliases": [ - "ip" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Isoproscaline", - "aliases": [ - "ip" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "30mg", - "Light": "40-50mg", - "Common": "50-60mg", - "Strong": "60-80mg+" - } - }, - "formatted_duration": { - "value": "10-20", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-180", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 148 - }, - "dph": { - "name": "dph", - "properties": { - "summary": "An antihistamine which, when taken in smaller doses relieves allergies and insomnia. In larger doses works as a deliriant and can actually keep the user awake. Generally the 'high' of this drug is reported as dysphoric, potentially causing hallucinations indistinguishable from reality.", - "avoid": "Many oral diphenhydramine preparations contain analgesics such as acetaminophen/paracetamol or aspirin, which can be toxic to the liver in high doses.", - "effects": "Delirium, dream-like experiences, paranoia, visual and audio distortions, dry mouth, muscle cramps, nausea, dysphoria, tremors. Often described as a pretty negative experience.", - "dose": "Oral Light: 100-250mg Common: 200-500mg Strong: 450-700mg NOTE: The doses provided are for recreational usage. For use as a sleep aid the dose ranges from 25-75mg, or as specified on the product packaging. For medical allergy use doses tend to range from 25-50mg, or as specified on the product packaging.", - "duration": "6-8 hours", - "onset": "60-120 minutes", - "categories": [ - "depressant", - "deliriant", - "common" - ], - "aliases": [ - "diphenhydramine", - "benadryl" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "DPH", - "aliases": [ - "diphenhydramine", - "benadryl" - ], - "categories": [ - "depressant", - "deliriant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "100-250mg", - "Common": "200-500mg", - "Strong": "450-700mg", - "NOTE": "The" - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Delirium", - "dream-like experiences", - "paranoia", - "visual and audio distortions", - "dry mouth", - "muscle cramps", - "nausea", - "dysphoria", - "tremors", - "Often described as a pretty negative experience", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Diphenhydramine.shtml" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Brightness alteration": "https://psychonautwiki.org/wiki/Brightness_alteration", - "Cognitive dysphoria": "https://psychonautwiki.org/wiki/Cognitive_dysphoria", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Feelings of impending doom": "https://psychonautwiki.org/wiki/Feelings_of_impending_doom", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle cramps": "https://psychonautwiki.org/wiki/Muscle_cramps", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Paranoia": "https://psychonautwiki.org/wiki/Paranoia", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Peripheral information misinterpretation": "https://psychonautwiki.org/wiki/Peripheral_information_misinterpretation", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Photophobia": "https://psychonautwiki.org/wiki/Photophobia", - "Physical fatigue": "https://psychonautwiki.org/wiki/Physical_fatigue", - "Psychosis": "https://psychonautwiki.org/wiki/Psychosis", - "Restless leg syndrome": "https://psychonautwiki.org/wiki/Restless_leg_syndrome", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Shadow people": "https://psychonautwiki.org/wiki/Shadow_people", - "Tactile hallucinations": "https://psychonautwiki.org/wiki/Tactile_hallucinations", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unspeakable horrors": "https://psychonautwiki.org/wiki/Unspeakable_horrors", - "Vibrating vision": "https://psychonautwiki.org/wiki/Vibrating_vision", - "Visual haze": "https://psychonautwiki.org/wiki/Visual_haze" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: The doses provided are for recreational usage. For use as a sleep aid the dose ranges from 25-100mg, or as specified on the product packaging.", - "sources": { - "_general": [ - "Dose-dependent toxicity of diphenhydramine overdose - http://www.ncbi.nlm.nih.gov/pubmed/11204550" - ] - }, - "id": 149 - }, - "methylmorphenate": { - "name": "methylmorphenate", - "properties": { - "summary": "Stimulant of the phenylmorpholine class, an analogue of Methylphenidate where the piperidine ring has been replaced by a morpholine one, with ~1/10 potency.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ] - }, - "pretty_name": "Methylmorphenate", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "id": 150 - }, - "4f-pvp": { - "name": "4f-pvp", - "properties": { - "summary": "Fluornated analogue of a-PVP. Seems to be slightly less weaker than it's parent compound.", - "duration": "Insufflated: 2-4 hours.", - "onset": "Insufflated: 15-20 minutes.", - "dose": "Insufflated Light: 5-10mg Common: 10-20mg Strong: 20-25mg+", - "categories": [ - "tentative", - "stimulant", - "habit-forming" - ], - "aliases": [ - "4f-a-pvp", - "pfpvp" - ] - }, - "pretty_name": "4F-PVP", - "aliases": [ - "4f-a-pvp", - "pfpvp" - ], - "categories": [ - "tentative", - "stimulant", - "habit-forming" - ], - "formatted_dose": { - "Insufflated": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-25mg+" - } - }, - "formatted_duration": { - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "15-20", - "_unit": "minutes" - }, - "id": 151 - }, - "6-apb": { - "name": "6-apb", - "properties": { - "dose": "Light: 50-75mg Common: 75-125mg Heavy: 125mg+ | NOTE: Do not exceed 200mg in a night", - "duration": "8-14 hours", - "summary": "A stimulant, empathogen and analog of MDA. Typically more visual than MDMA or MDA, as well as having a much longer onset and duration. Users often report a slightly more psychedelic headspace as well. Commonly sold as an alternative to MDMA and MDA.", - "onset": "45-90 minutes.", - "effects": "Feelings of empathy, euphoria, and a general sense of well being. Light to moderate visuals are also reported with most users.", - "after-effects": "6-apb is reported to have a 'hangover' similar to MDMA.", - "aliases": [ - "6apb" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ] - }, - "pretty_name": "6-APB", - "aliases": [ - "6apb" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Light:": { - "Light": "50-75mg", - "Common": "75-125mg", - "Heavy": "125mg+" - } - }, - "formatted_duration": { - "value": "8-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Feelings of empathy", - "euphoria", - "and a general sense of well being", - "Light to moderate visuals are also reported with most users", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_6APB.shtml" - }, - "formatted_aftereffects": { - "value": "6-apb" - }, - "dose_note": " NOTE: Do not exceed 200mg in a night", - "id": 152 - }, - "25g-nbome": { - "name": "25g-nbome", - "properties": { - "summary": "A rare psychedelic stimulant and bomamine. A derivative of 2C-G, but far more potent. Likely to have hallucinogenic, stimulant and vasoconstrictive properties which may be dangerous at high doses. A heavy body load is to be expected.", - "dose": "Buccal/Sublingual Threshold: 500ug Light: 1000-1500ug Common: 1500-2000ug Strong: 2000ug+ | NOTE: Users report wildly varying reactions to the same doses. Start low and work your way up.", - "duration": "5-7 hours.", - "onset": "30-50 minutes", - "after-effects": "1-2 hours", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "aliases": [ - "25g", - "25gnbome" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "25G-NBOMe", - "aliases": [ - "25g", - "25gnbome" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Buccal/Sublingual": { - "Threshold": "500ug", - "Light": "1000-1500ug", - "Common": "1500-2000ug", - "Strong": "2000ug+" - } - }, - "formatted_duration": { - "value": "5-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-50", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_25GNBOMe.shtml" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "dose_note": " NOTE: Users report wildly varying reactions to the same doses. Start low and work your way up.", - "id": 153 - }, - "5-meo-dibf": { - "name": "5-meo-dibf", - "properties": { - "summary": "An uncommon and new psychedelic drug related to tryptamine; the Benzofuran analogue of 5-MeO-DiPT. Probably a serotonin receptor partial agonist. Little history of human use.", - "onset": "Oral: 20-90 minutes. | Insufflated: 5-45 minutes.", - "dose": "Oral Light: 10-20mg Common: 20-40mg Strong: 40-60mg+ | Insufflated Light: 5-10mg Common: 10-15mg Strong: 15-20mg+", - "duration": "Oral 8-12 hours. | Insufflated 6-8 hours.", - "categories": [ - "empathogen", - "research-chemical", - "tentative" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "5-MeO-DIBF", - "categories": [ - "empathogen", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-40mg", - "Strong": "40-60mg+" - }, - "Insufflated": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-20mg+" - } - }, - "formatted_duration": { - "Oral": "8-12", - "Insufflated": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-90", - "Insufflated": "5-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeODiBF.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 154 - }, - "aminorex": { - "name": "aminorex", - "properties": { - "summary": "Is an anorectic stimulant drug that was taken of the market after it was found to cause pulmonary hypertension. Potency wise it has been found to be roughly 2.5 times more potent than dextroamphetamine.", - "onset": "10-30 minutes.", - "duration": "4-8 hours.", - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ] - }, - "pretty_name": "Aminorex", - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "none": { - "Light": "1-3mg", - "Common": "3-10mg", - "Strong": "10-25mg." - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "id": 155 - }, - "hexedrone": { - "name": "hexedrone", - "properties": { - "summary": "A rare mephedrone analogue also known as MACP, a cathinone stimulant with similar effects to pentedrone.", - "duration": "1-4 hours.", - "onset": "15-30 minutes.", - "dose": "Threshold: 30-50mg Light: 50-70mg Common: 70-100mg Strong: 100-125mg+ | NOTE: These doses are tentative and may need further research.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "avoid": "Other stimulants. ", - "after-effects": "1-12 hours." - }, - "pretty_name": "Hexedrone", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "30-50mg", - "Light": "50-70mg", - "Common": "70-100mg", - "Strong": "100-125mg+" - } - }, - "formatted_duration": { - "value": "1-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 156 - }, - "2c-b": { - "name": "2c-b", - "properties": { - "dose": "Oral Light: 5-15mg Common: 15-30mg Strong: 30-50mg Heavy: 50mg+ | Insufflated/Plugged Light: 5-10mg Common: 10-20mg Strong: 20-30mg Heavy: 30mg+", - "onset": "Oral: 20-75 minutes | Insufflated: 1-10 minutes | Plugged: 5-20 minutes", - "duration": "Oral: 4-8 hours | Insufflated: 2-4 hours | Plugged: 3-5 hours", - "after-effects": "2-4 hours", - "effects": "euphoria, giggling, empathy, insight, brightened color, closed/open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception of time, ego softening, nausea, sweating/chills, muscle tension, confusion, insomnia", - "aliases": [ - "bees", - "nexus", - "2cb", - "2cb", - "2-cb" - ], - "summary": "A popular psychedelic in the phenethylamine family. Provides empathic experiences at lower doses and strong visual and psychedelic experiences at higher doses. Commonly used as a party drug as it is more clear-headed than most psychedelics. 2C-B has been in use since the early 1990s", - "categories": [ - "psychedelic", - "empathogen", - "common" - ], - "test-kits": "Marquis: Yellow > Green. | Mecke: Yellow > Green/Brown. | Mandelin: Green. | Froehde: Yellow > Green. | Liebermann: Yellow > Black. | Simon's No colour change or Purple. | Ehrlich: No colour change." - }, - "pretty_name": "2C-B", - "aliases": [ - "bees", - "nexus", - "2cb", - "2cb", - "2-cb" - ], - "categories": [ - "psychedelic", - "empathogen", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg", - "Heavy": "50mg+" - }, - "Insufflated/Plugged": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-30mg", - "Heavy": "30mg+" - } - }, - "formatted_duration": { - "Oral": "4-8", - "Insufflated": "2-4", - "Plugged": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-75", - "Insufflated": "1-10", - "Plugged": "5-20", - "_unit": "minutes" - }, - "formatted_effects": [ - "euphoria", - "giggling", - "empathy", - "insight", - "brightened color", - "closed/open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception of time", - "ego softening", - "nausea", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CB.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal020.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depth perception distortions": "https://psychonautwiki.org/wiki/Depth_perception_distortions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Feelings of predeterminism": "https://psychonautwiki.org/wiki/Feelings_of_predeterminism", - "Feelings of self-design": "https://psychonautwiki.org/wiki/Feelings_of_self-design", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Rejuvenation": "https://psychonautwiki.org/wiki/Rejuvenation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Visual haze": "https://psychonautwiki.org/wiki/Visual_haze" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "sources": { - "_general": [ - "In vivo metabolism of 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in the rat: identification of urinary metabolites - http://www.ncbi.nlm.nih.gov/pubmed/11916016" - ] - }, - "id": 157 - }, - "ethylmorphine": { - "name": "ethylmorphine", - "properties": { - "onset": "15-30 minutes.", - "duration": "4-5 hours.", - "dose": "Light: 40-50mg Common: 50-100mg Strong: 100-200mg+", - "Avoid": "All CNS depressants.", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "summary": "A medium-strength opioid analgesic and analogue of morphine. Considered less potent than morphine but more potent than codeine, and has been used in Germany for this reason. Said to have a 'ceiling' effect where no more euphoria occurs with increased dosage. Under investigation as a maintainance drug in opioid dependence therapy.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Ethylmorphine", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "40-50mg", - "Common": "50-100mg", - "Strong": "100-200mg+" - } - }, - "formatted_duration": { - "value": "4-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Stomach cramps": "https://psychonautwiki.org/wiki/Stomach_cramps" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 158 - }, - "2-methyl-2-butanol": { - "name": "2-methyl-2-butanol", - "properties": { - "summary": "A tertiary alcohol that has sedative, hypnotic, and anxiolytic effects. It is also roughly 20x more potent than Ethanol by weight.", - "categories": [ - "habit-forming", - "depressant", - "tentative" - ], - "aliases": [ - "2m2b" - ], - "onset": "5-25 minutes.", - "duration": "4-8 hours.", - "dose": "Oral Light: 2.5-5g Common: 5-7.5g Strong: 7.5-15g+", - "avoid": "All other CNS depressants.", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "2-6 hours." - }, - "pretty_name": "2-methyl-2-butanol", - "aliases": [ - "2m2b" - ], - "categories": [ - "habit-forming", - "depressant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5g", - "Common": "5-7.5g", - "Strong": "7.5-15g+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-25", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2Methyl2Butanol.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "id": 159 - }, - "pseudoephedrine": { - "name": "pseudoephedrine", - "properties": { - "summary": "Widely sold as a decongestant, and one isomer of Ephedrine. It is not generally considered to have any recreational value. Is also used in the synthesis of Methcathinone and Methamphetamine.", - "onset": "10-90 minutes.", - "duration": "2-12 hours.", - "dose": "Oral Light: 30-60mg. Common: 60-90mg. Strong: 90-120mg.", - "avoid": "If you're prone to a pre-exisiting condition regarding your heart.", - "categories": [ - "stimulant", - "common" - ] - }, - "pretty_name": "Pseudoephrine", - "categories": [ - "stimulant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "30-60mg.", - "Common": "60-90mg.", - "Strong": "90-120mg." - } - }, - "formatted_duration": { - "value": "2-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-90", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Pseudoephedrine.shtml" - }, - "id": 160 - }, - "phenethylamine": { - "name": "phenethylamine", - "properties": { - "summary": "Organic compound, which is a name of a class of chemicals that are quite well known for psychoactive and/or stimulant effects. Normally not used as a supplement as it is rapidly broken down into inactive compounds. Is found in many foods.", - "dose": "Common: 300-500mg.", - "duration": "1-4 hours.", - "onset": "15-30 minutes.", - "after-effects": "10-60 minutes.", - "categories": [ - "supplement", - "nootropic" - ], - "aliases": [ - "pea" - ] - }, - "pretty_name": "Phenethylamine", - "aliases": [ - "pea" - ], - "categories": [ - "supplement", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Common": "300-500mg." - } - }, - "formatted_duration": { - "value": "1-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "10-60", - "_unit": "minutes" - }, - "id": 161 - }, - "ah-7921": { - "name": "ah-7921", - "properties": { - "summary": "Opioid analgesic that is selective for the μ-opioid receptor. It has around 80% the potency of Morphine when taken orally.", - "dose": "Oral Light: 10-20mg Common: 20-40mg Strong: 40mg+ Vapourized Light: 5-10mg Common: 10-25mg Strong: 25mg+", - "onset": "Oral: 15-45 minutes. | Vaporized: 2-10 minutes.", - "duration": "Oral: 6-8 hours | Vaporized 3-4 hours.", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "aliases": [ - "ah7921" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-6 hours." - }, - "pretty_name": "AH-7921", - "aliases": [ - "ah7921" - ], - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-25mg", - "Strong": "25mg+" - } - }, - "formatted_duration": { - "Oral": "6-8", - "Vaporized": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Vaporized": "2-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_AH7921.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 162 - }, - "4-cmc": { - "name": "4-cmc", - "properties": { - "onset": "Oral: 20-60 minutes. Insufflated: 10-40 minutes.", - "duration": "Oral: 2-4 hours Insufflated 1-3 hours.", - "dose": "Oral Threshold: 20-30mg Light: 30-50mg Common: 50mg-100mg Strong: 100mg+", - "summary": "(Note this work is going off just a few users inputs, so take all of this with a grain of salt) The cathinone analogue of 4-CMA which is highly neurotoxic. It is not known if the cathinone family holds the same neurotoxicity problem as with the parent compound.", - "after-effects": "Few hours like most stimulants.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "aliases": [ - "4cmc" - ] - }, - "pretty_name": "4-CMC", - "aliases": [ - "4cmc" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "20-30mg", - "Light": "30-50mg", - "Common": "50mg-100mg", - "Strong": "100mg+" - } - }, - "formatted_duration": { - "Oral": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "Few", - "_unit": "hours" - }, - "id": 163 - }, - "dextropropoxyphene": { - "name": "dextropropoxyphene", - "properties": { - "dose": "Light: 30-65mg Common: 65-100mg Strong: 100-200mg NOTE: It was taken off the market in some countries due to issues relating to the Kidney, Liver, Heart and Respiratory Disorders.", - "aliases": [ - "darvocet", - "co-proxamol", - "coproxamol", - "capadex", - "di-gesic" - ], - "summary": "An opioid analgesic that is an optical isomer of levopropoxyphene. Used to treat mild pain and often used for its antitussive properties. It has been taken off the market in Europe and US due to concerns of health issues relating to the Kidney, Liver, Heart and Respiratory Disorders. Just a bit stronger than Tramadol.", - "onset": "20-30 minutes.", - "duration": "1-3 hours.", - "after-effects": "1-6 hours.", - "avoid": "All CNS depressants. And all together if you have a history of issues with your Kidneys, Liver, Heart and any Respiratory Disorders.", - "categories": [ - "opioid", - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Dextropropoxyphene", - "aliases": [ - "darvocet", - "co-proxamol", - "coproxamol", - "capadex", - "di-gesic" - ], - "categories": [ - "opioid", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "30-65mg", - "Common": "65-100mg", - "Strong": "100-200mg", - "NOTE": "It" - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 164 - }, - "pipt": { - "name": "pipt", - "properties": { - "onset": "Vaped: 5 minutes. | Oral: 1 hour.", - "dose": "Vapourized Threshold: 10mg Light: 15mg Common: 15-20mg Heavy: 20mg+", - "duration": "Oral: 3-4 hours | Vaped: 2 hours", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "summary": "A rare psychedelic tryptamine related to DPT. Little is known about the effects or safety profile of this compound.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-4 hours." - }, - "pretty_name": "PiPT", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Vapourized": { - "Threshold": "10mg", - "Light": "15mg", - "Common": "15-20mg", - "Heavy": "20mg+" - } - }, - "formatted_duration": { - "Oral": "3-4", - "Vaped": "2", - "_unit": "hours" - }, - "formatted_onset": { - "Vaped": "5", - "Oral": "1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 165 - }, - "dimethylone": { - "name": "dimethylone", - "properties": { - "summary": "Inactive.", - "categories": [ - "inactive" - ] - }, - "pretty_name": "Dimethylone", - "categories": [ - "inactive" - ], - "id": 166 - }, - "25p-nbome": { - "name": "25p-nbome", - "properties": { - "summary": "A rare potent psychedelic drug with similar effects and risks to others in the NBOMe class. Yet no trip reports... when the substance was first sold in mid-late 2012, and resurfaced in early 2015.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "onset": "25-40 minutes.", - "duration": "7-14 hours.", - "dose": "Threshold: 100-250ug Light: 250-450ug Common: 450-700ug Strong: 700-1500ug", - "after-effects": "1-16 hours." - }, - "pretty_name": "25P-NBOMe", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "100-250ug", - "Light": "250-450ug", - "Common": "450-700ug", - "Strong": "700-1500ug" - } - }, - "formatted_duration": { - "value": "7-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "25-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "id": 167 - }, - "deschloroetizolam": { - "name": "deschloroetizolam", - "properties": { - "summary": "A Thienodiazepine which is close to its parent compound, Etizolam, whilst being significantly weaker and longer lasting.", - "onset": "1-5 minutes", - "duration": "8-10 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "dose": "Oral Light: 2-4mg Common: 4-6mg Strong: 6-12mg | NOTE: Non-oral ROAs are ineffective.", - "aliases": [ - "etizolam-2" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-8 hours." - }, - "pretty_name": "Deschloroetizolam", - "aliases": [ - "etizolam-2" - ], - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2-4mg", - "Common": "4-6mg", - "Strong": "6-12mg" - } - }, - "formatted_duration": { - "value": "8-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " NOTE: Non-oral ROAs are ineffective.", - "id": 168 - }, - "bromo-dragonfly": { - "name": "bromo-dragonfly", - "properties": { - "summary": "A psychedelic phenethylamine and benzofuran that is very potent and has a long duration. Was briefly sold as \"2C-B-FLY\" in 2005/6 and has lead to multiple deaths.", - "dose": "Oral Threshold: 100ug Common: 100-400ug Strong: 500-750ug+", - "onset": "Up to 6 hours.", - "duration": "16-30 hours.", - "after-effects": "Up to many days.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "aliases": [ - "bromo-d-fly", - "bdfly", - "bromo-dragon-fly", - "dob-dragonfly" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Bromo-DragonFLY", - "aliases": [ - "bromo-d-fly", - "bdfly", - "bromo-dragon-fly", - "dob-dragonfly" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "100ug", - "Common": "100-400ug", - "Strong": "500-750ug+" - } - }, - "formatted_duration": { - "value": "16-30", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Up", - "_unit": "hours" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_BromoDragonfly.shtml" - }, - "formatted_aftereffects": { - "value": "Up" - }, - "id": 169 - }, - "cloxazolam": { - "name": "cloxazolam", - "properties": { - "summary": "Benzodiazepine derivate that is metabolised into Delorazepam. Which is where most of its effects come from.", - "dose": "Light: 1.5-3mg Common: 3-6mg Strong: 6-12mg+", - "onset": "15-45 minutes.", - "duration": "7-12 hours.", - "after-effects": "4-12 hours.", - "categories": [ - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Cloxazolam", - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "1.5-3mg", - "Common": "3-6mg", - "Strong": "6-12mg+" - } - }, - "formatted_duration": { - "value": "7-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "4-12", - "_unit": "hours" - }, - "id": 170 - }, - "tiletamine": { - "name": "tiletamine", - "properties": { - "onset": "Oral: 15-45 minutes. | Insufflated: 2-10 minutes. | Intramuscular: 1-5 minutes.", - "summary": "A relatively rare dissociative anesthetic, pharmacologically classified as an NMDA receptor antagonist. It is related to other anesthetics in this family such as Ketamine and phencyclidine. Has been used to cut Ketamine, in which case it may cause additional nausea. In Veterinary practice it is mixed with Zolazolam, a potent anaesthetic at a 1:1 ratio.", - "categories": [ - "dissociative", - "research-chemical", - "tentative", - "habit-forming" - ], - "duration": "Oral: 6-12 hours. | Insufflated: 2-5 hours. | Intramuscular: 1-4 hours.", - "aliases": [ - "telazol" - ], - "dose": "Oral Light: 10-25mg Common: 25-50mg Strong: 50-100mg+ | Intramuscular Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg+", - "after-effects": "1-72 hours." - }, - "pretty_name": "Tiletamine", - "aliases": [ - "telazol" - ], - "categories": [ - "dissociative", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-100mg+" - }, - "Intramuscular": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "Oral": "6-12", - "Insufflated": "2-5", - "Intramuscular": "1-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Insufflated": "2-10", - "Intramuscular": "1-5", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-72", - "_unit": "hours" - }, - "id": 171 - }, - "butylone": { - "name": "butylone", - "properties": { - "summary": "Empathogen and stimulant of the cathinone class.", - "aliases": [ - "bk-mbdb", - "b1", - "bk-methyl-j" - ], - "onset": "25-45 minutes", - "duration": "3-5 hours.", - "dose": "Oral Threshold: 20-40mg Light: 40-70mg Common: 70-100mg Strong: 150-200mg Heavy: 200mg+", - "after-effects": "2-12 hours.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ] - }, - "pretty_name": "Butylone", - "aliases": [ - "bk-mbdb", - "b1", - "bk-methyl-j" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Threshold": "20-40mg", - "Light": "40-70mg", - "Common": "70-100mg", - "Strong": "150-200mg", - "Heavy": "200mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "25-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_bkMBDB.shtml" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 172 - }, - "jenkem": { - "name": "jenkem", - "properties": { - "summary": "A hoax which began in online communities of a non-existent drug which was claimed to result from a process involving human waste. http://www.snopes.com/crime/warnings/jenkem.asp", - "categories": [ - "deliriant", - "tentative" - ] - }, - "pretty_name": "Jenkem", - "categories": [ - "deliriant", - "tentative" - ], - "id": 173 - }, - "ketamine": { - "name": "ketamine", - "properties": { - "dose": "Insufflated Threshold: 5-10mg Light: 20-50mg Common: 50-125mg Strong: 125-175mg Heavy: 175-250mg | NOTE: Ketamine is based on weight. These are figures for the average 150 pound male There is no concrete dose for the \"K-Hole\" as each user is different.", - "duration": "1-2 hours", - "summary": "A short acting dissociative anaesthetic and hallucinogen commonly used in emergency medicine. It is the prototypical dissociative, and is widely used at sub-anesthetic doses recreationally. Small doses are comparable with alcohol, while larger doses are immobilising and lead to psychedelic experiences: the \"K-Hole.\"", - "onset": "Insufflated: 7.5-20 minutes | Oral: 10-75 minutes | Intramuscular: 2-7.5 minutes | Intravenous: 0-2 minutes", - "avoid": "Driving. Moving and walking if possible. Mixing with other depressants like alcohol, benzos and opiates.", - "effects": "A feeling of drunkenness and well being at low doses. As dose increases the user may begin to feel a disconnection from their body. At 'khole' doses the user may become completely disconnected from both body and mind.", - "aliases": [ - "k", - "ket", - "kitty", - "kittens" - ], - "molecule": "http://wiki.tripsit.me/images/7/76/Ketamine.png", - "categories": [ - "dissociative", - "habit-forming", - "common" - ], - "after-effects": "1-2 hours" - }, - "pretty_name": "Ketamine", - "aliases": [ - "k", - "ket", - "kitty", - "kittens" - ], - "categories": [ - "dissociative", - "habit-forming", - "common" - ], - "formatted_dose": { - "Insufflated": { - "Threshold": "5-10mg", - "Light": "20-50mg", - "Common": "50-125mg", - "Strong": "125-175mg", - "Heavy": "175-250mg" - } - }, - "formatted_duration": { - "value": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "7.5-20", - "Oral": "10-75", - "Intramuscular": "2-7.5", - "Intravenous": "0-2", - "_unit": "minutes" - }, - "formatted_effects": [ - "A feeling of drunkenness and well being at low doses", - "As dose increases the user may begin to feel a disconnection from their body", - "At 'khole' doses the user may become completely disconnected from both body and mind", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ketamine.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Suggestibility enhancement": "https://psychonautwiki.org/wiki/Suggestibility_enhancement", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection", - "Visual sliding": "https://psychonautwiki.org/wiki/Visual_sliding" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "dose_note": " NOTE: Ketamine is based on weight. These are figures for the average 150 pound male There is no concrete dose for the \"K-Hole\" as each user is different.", - "sources": { - "_general": [ - "Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model ps.. - https://www.ncbi.nlm.nih.gov/pubmed/16143730", - "The effect of ketamine on opioid-induced acute tolerance: can it explain reduction of opioid consumption with ketamine-opioid analgesic combinations - http://www.ncbi.nlm.nih.gov/pubmed/11094005", - "Subanesthetic ketamine infusion therapy: a retrospective analysis of a novel therapeutic approach to complex regional pain syndrome - http://www.ncbi.nlm.nih.gov/pubmed/15367304", - "Effects of ketamine on precipitated opiate withdrawal - http://www.ncbi.nlm.nih.gov/pubmed/16963828", - "Low-dose ketamine with multimodal postcesarean delivery analgesia: a randomized controlled trial - http://www.ncbi.nlm.nih.gov/pubmed/21224020", - "Chronic ketamine exposure induces permanent impairment of brain functions in adolescent cynomolgus monkeys - http://www.ncbi.nlm.nih.gov/pubmed/23145560", - "GLYX-13, a NMDA receptor glycine-site functional partial agonist, induces antidepressant-like effects without ketamine-like side effects - http://www.ncbi.nlm.nih.gov/pubmed/23303054", - "From \"Special K\" to \"Special M\": the evolution of the recreational use of ketamine and methoxetamine - http://www.ncbi.nlm.nih.gov/pubmed/23421859", - "Daily oral ketamine for the treatment of depression and anxiety in patients receiving hospice care: a 28-day open-label proof-of-concept trial - http://www.ncbi.nlm.nih.gov/pubmed/23805864", - "Brain damages in ketamine addicts as revealed by magnetic resonance imaging - http://www.ncbi.nlm.nih.gov/pubmed/23882190", - "Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial - http://www.ncbi.nlm.nih.gov/pubmed/23982301", - "Are sexes affected differently by ketamine? An exploratory study in ketamine users - http://www.ncbi.nlm.nih.gov/pubmed/24106975", - "Therapeutic infusions of ketamine: do the psychoactive effects matter - http://www.ncbi.nlm.nih.gov/pubmed/24480515", - "The absolute bioavailability of racemic ketamine from a novel sublingual formulation - http://www.ncbi.nlm.nih.gov/pubmed/24977293", - "The mood stabilizer lithium potentiates the antidepressant-like effects and ameliorates oxidative stress induced by acute ketamine in a mouse model.. - http://www.ncbi.nlm.nih.gov/pubmed/25548109", - "The promise of ketamine for treatment-resistant depression: current evidence and future directions - http://www.ncbi.nlm.nih.gov/pubmed/25649308", - "Antidepressants do not increase the lethality of ketamine in mice - http://www.ncbi.nlm.nih.gov/pubmed/6849728", - "Effect of ketamine, an NMDA receptor inhibitor, in acute and chronic orofacial pain - http://www.ncbi.nlm.nih.gov/pubmed/7659431", - "Ketamine and norketamine plasma concentrations after i.v., nasal and rectal administration in children - http://www.ncbi.nlm.nih.gov/pubmed/8881626", - "Tissue distribution of ketamine in a mixed drug fatality - http://www.ncbi.nlm.nih.gov/pubmed/9397567", - "[From the racemate to the eutomer: (S)-ketamine. Renaissance of a substance?] - http://www.ncbi.nlm.nih.gov/pubmed/9451486", - "Chronic abuse has led to a case of kidney and liver damage http://www.ncbi.nlm.nih.gov/pubmed/24982568", - "ketamine in the hospital setting can raise blood pressure and is something to be considered when using it: \"Emergency care in the streets\"", - "Ketamine shows promise in treating suicidal ideation in patients with depression - http://www.biologicalpsychiatryjournal.com/article/S0006-3223(09)00519-8/abstract" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Low Risk & Synergy", - "note": "Ketamine and psychedelics tend to potentiate each other - go slowly." - }, - "nbomes": { - "status": "Low Risk & Synergy" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Low Risk & Synergy" - }, - "amt": { - "status": "Low Risk & Synergy" - }, - "5-meo-xxt": { - "status": "Low Risk & Synergy" - }, - "cannabis": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & No Synergy" - }, - "pcp": { - "status": "Low Risk & Synergy" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury." - }, - "mdma": { - "status": "Low Risk & Synergy", - "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury." - }, - "cocaine": { - "status": "Caution", - "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury." - }, - "caffeine": { - "status": "Low Risk & No Synergy", - "note": "No unexpected interactions." - }, - "alcohol": { - "status": "Dangerous", - "note": "Both substances cause ataxia and bring a very high risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position." - }, - "ghb/gbl": { - "status": "Dangerous", - "note": "Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position." - }, - "opioids": { - "status": "Dangerous", - "note": "Both substances bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position." - }, - "tramadol": { - "status": "Dangerous" - }, - "benzodiazepines": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position." - }, - "benzos": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position." - }, - "maois": { - "status": "Caution", - "note": "MAO-B inhibitors appear to increase the potency of Ketamine. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available" - }, - "ssris": { - "status": "Low Risk & No Synergy" - } - }, - "id": 174 - }, - "diclofensine": { - "name": "diclofensine", - "properties": { - "summary": "A triple monoamine reuptake inhibitor developed by Hoffman-LaRoche in the 1970s as an antidepressant but discontinued, probably due to high abuse potential. Has not become popular as a recreational drug at this time. Acts as an SNDRI, mostly inhibits dopamine and noradrenaline.", - "aliases": [ - "ro8-4650" - ], - "dose": "Threshold: 12-15mg Low: 30-40mg Common: 40-60mg Heavy: 60-80mg | NOTE: These doses are tentative and may need further research.", - "duration": "4-6 hours", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ] - }, - "pretty_name": "Diclofensine", - "aliases": [ - "ro8-4650" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "12-15mg", - "Low": "30-40mg", - "Common": "40-60mg", - "Heavy": "60-80mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 175 - }, - "6-apdb": { - "name": "6-apdb", - "properties": { - "summary": "A stimulant and entactogen related to MDMA and an analogue of MDA. Reported as being fairly psychedlic at higher doses. It is a triple monoamine reuptake inhibitor. Potent full agonist of serotonin 2B receptors.", - "dose": "Oral Threshold: 25-30mg Low: 30-40mg Medium: 40-75mg Heavy: 75-100+mg", - "onset": "60-90 minutes.", - "duration": "7-9 hours, up to 12 reported", - "after-effects": "Some users report feeling drained the next day lasting a few days. Varies person to person.", - "aliases": [ - "4-desoxy-mda" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "6-APDB", - "aliases": [ - "4-desoxy-mda" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "25-30mg", - "Low": "30-40mg", - "Medium": "40-75mg", - "Heavy": "75-100+mg" - } - }, - "formatted_duration": { - "value": "7-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_6APDB.shtml" - }, - "formatted_aftereffects": { - "value": "Some" - }, - "id": 176 - }, - "lsa": { - "name": "lsa", - "properties": { - "dose": "HBWR Light: 1-2seeds Common: 2-6seeds Strong: 6-14seeds Heavy: 14seeds+ | Morning_Glory Light: 50-100seeds Common: 100-250seeds Strong: 250-400seeds Heavy: 400seeds+", - "onset": "30-180 minutes", - "duration": "4-10 hours", - "after-effects": "Some users report a hangover, characterized by a feeling of mental sluggishness and dulled emotions.", - "summary": "A chemical found in Morning Glory and Hawaiian Baby Woodrose seeds, which are often legally available. Has mental effects similar to LSD, although with almost no visual effects. It is famous for being very nauseating, and for causing excessive time dilation at higher doses.", - "aliases": [ - "hbwr", - "morningglory", - "hbmg", - "Morning", - "ololiuqui", - "morning_glory", - "hbw" - ], - "categories": [ - "psychedelic", - "common" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "LSA", - "aliases": [ - "hbwr", - "morningglory", - "hbmg", - "Morning", - "ololiuqui", - "morning_glory", - "hbw" - ], - "categories": [ - "psychedelic", - "common" - ], - "formatted_dose": { - "HBWR": { - "Light": "1-2seeds", - "Common": "2-6seeds", - "Strong": "6-14seeds", - "Heavy": "14seeds+" - }, - "Morning_Glory": { - "Light": "50-100seeds", - "Common": "100-250seeds", - "Strong": "250-400seeds", - "Heavy": "400seeds+" - } - }, - "formatted_duration": { - "value": "4-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-180", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_LSA.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Perception of increased weight": "https://psychonautwiki.org/wiki/Perception_of_increased_weight", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "Some" - }, - "id": 177 - }, - "focalin": { - "name": "focalin", - "properties": { - "summary": "The psychoactive isomer of methylphenidate, mostly used to treat ADHD. Twice as potent as methylphenidate, and is said to have cleaner psychostimulant effects with fewer side effects.", - "aliases": [ - "dexmethylphenidate", - "dextromethylphenidate" - ], - "dose": "Oral Light: 10-20mg Common: 20-30mg Strong: 30-40mg Heavy: 40-50mg", - "onset": "45-90 mintues.", - "duration": "9-12 hours", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Dexmethylphenidate", - "aliases": [ - "dexmethylphenidate", - "dextromethylphenidate" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-30mg", - "Strong": "30-40mg", - "Heavy": "40-50mg" - } - }, - "formatted_duration": { - "value": "9-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 178 - }, - "psilocin": { - "name": "psilocin", - "properties": { - "summary": "Psilocin is a substutued tryptamine alkaloid, that is present in most psychedelic mushrooms. It is relatively unstable in solution due to the -OH group.", - "dose": "Oral Light: 5-10mg Common: 10-15mg Strong: 15-25mg | Insufflated Light: 2.5-5mg Common: 5-10mg Strong: 10-15mg", - "duration": "Oral: 3-6 hours | Insufflated: 2-4 hours.", - "onset": "Oral: 15-30 minutes. | Insufflated: 5-10 minutes.", - "after-effects": "3-12 hours.", - "aliases": [ - "4-ho-dmt", - "4-oh-dmt" - ], - "categories": [ - "psychedelic", - "tentative", - "empathogen", - "research-chemical" - ] - }, - "pretty_name": "Psilocin", - "aliases": [ - "4-ho-dmt", - "4-oh-dmt" - ], - "categories": [ - "psychedelic", - "tentative", - "empathogen", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-25mg" - }, - "Insufflated": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-15mg" - } - }, - "formatted_duration": { - "Oral": "3-6", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "3-12", - "_unit": "hours" - }, - "id": 179 - }, - "4-aco-det": { - "name": "4-aco-det", - "properties": { - "dose": "Oral Threshold: 2-5mg's Light: 5-15mg's Common: 10-15mg's. Strong: 15-30mg's+\"", - "duration": "Oral: 2-6 hours.", - "after-effects": "1-6 hours.", - "onset": "15-60 minutes (Dependant on form and stomach contents)", - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ], - "aliases": [ - "ethacetin", - "ethylacybin", - "4-acetoxy-det" - ], - "summary": "Rare drug that is of the tryptamine family, can be comparable to Psilocybin. Expected to quickly hydrolyzed into the free phenolic 4-HO-DET." - }, - "pretty_name": "4-AcO-DET", - "aliases": [ - "ethacetin", - "ethylacybin", - "4-acetoxy-det" - ], - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "2-5mg", - "Light": "5-15mg", - "Common": "10-15mg", - "Strong": "15-30mg" - } - }, - "formatted_duration": { - "Oral": "2-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4AcODET.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 180 - }, - "2-mppp": { - "name": "2-mppp", - "properties": { - "summary": "A novel stimulant that is similar to methcathinone.", - "duration": "2-4 hours", - "dose": "Oral Light: 25-50mg Common: 50-100mg Strong: 100-150mg Heavy: 150mg+. | Insufflated Light: 15-30mg Common: 30-60mg Strong: 60-110mg Heavy: 110mg+", - "onset": "Oral: 10-20 minutes | Rectal 10-15 minutes", - "aliases": [ - "n-piperidinecathinone" - ], - "categories": [ - "research-chemical", - "habit-forming", - "stimulant", - "tentative" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "after-effects": "1-12 hours." - }, - "pretty_name": "2-MPPP", - "aliases": [ - "n-piperidinecathinone" - ], - "categories": [ - "research-chemical", - "habit-forming", - "stimulant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50mg", - "Common": "50-100mg", - "Strong": "100-150mg", - "Heavy": "150mg+." - }, - "Insufflated": { - "Light": "15-30mg", - "Common": "30-60mg", - "Strong": "60-110mg", - "Heavy": "110mg+" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-20", - "Rectal": "10-15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 181 - }, - "5-meo-met": { - "name": "5-meo-met", - "properties": { - "dose": "Oral Threshold 5-7mg Light: 13-15mg Common: 15-25mg Strong: 25mg+ | Vapourized Threshold: ~1mg Light: 1-5mg Common: 5-8mg Strong: 8-12mg+", - "duration": "Oral: 2-3 hours. Vapourized 60-90 minutes.", - "summary": "An obscure psychedelic drug similar in structure to 5-MeO-DMT. Possibly first synthesised by Alexander Shulgin. Likely to have similar effects to other tryptamine psychedelics.", - "after-effects": "1-2 hours.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "onset": "Oral: 10-45 minutes. | Vapourized: 1-5 minutes." - }, - "pretty_name": "5-MeO-MET", - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "13-15mg", - "Common": "15-25mg", - "Strong": "25mg+" - }, - "Vapourized": { - "Light": "1-5mg", - "Common": "5-8mg", - "Strong": "8-12mg+" - } - }, - "formatted_duration": { - "Oral": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-45", - "Vapourized": "1-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "id": 182 - }, - "oxazolam": { - "name": "oxazolam", - "properties": { - "summary": "A benzodiazepine derivative that is a prodrug for desmethyldiazepam.", - "dose": "Light: 5-10mg Common: 10-15mg Strong: 15-30mg+", - "duration": "6-12 hours.", - "onset": "30-90 minutes.", - "after-effects": "6-12 hours.", - "categories": [ - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Oxazolam", - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-30mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "6-12", - "_unit": "hours" - }, - "id": 183 - }, - "scopolamine": { - "name": "scopolamine", - "properties": { - "avoid": "Yes. Just avoid it. One of the active substances in Datura.", - "summary": "The main active compound in datura, medium and high doses have serious side effects and cause extremely unpleasant deleriant hallucinations. Avoid it.", - "categories": [ - "deliriant", - "tentative" - ] - }, - "pretty_name": "Scopolamine", - "categories": [ - "deliriant", - "tentative" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Scopolamine.shtml" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive dysphoria": "https://psychonautwiki.org/wiki/Cognitive_dysphoria", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Muscle cramps": "https://psychonautwiki.org/wiki/Muscle_cramps", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Paranoia": "https://psychonautwiki.org/wiki/Paranoia", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of increased weight": "https://psychonautwiki.org/wiki/Perception_of_increased_weight", - "Peripheral information misinterpretation": "https://psychonautwiki.org/wiki/Peripheral_information_misinterpretation", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Photophobia": "https://psychonautwiki.org/wiki/Photophobia", - "Psychosis": "https://psychonautwiki.org/wiki/Psychosis", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Restless leg syndrome": "https://psychonautwiki.org/wiki/Restless_leg_syndrome", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Shadow people": "https://psychonautwiki.org/wiki/Shadow_people", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unspeakable horrors": "https://psychonautwiki.org/wiki/Unspeakable_horrors", - "Vibrating vision": "https://psychonautwiki.org/wiki/Vibrating_vision", - "Visual haze": "https://psychonautwiki.org/wiki/Visual_haze" - }, - "id": 184 - }, - "3c-e": { - "name": "3c-e", - "properties": { - "duration": "8-14 hours", - "dose": "Threshold: 15-25mg Light: 25-35mg Common: 35-50mg Strong: 50-70mg+", - "summary": "Three-Carbon Analog of Escaline. Substituted Amphetamine.", - "categories": [ - "psychedelic", - "research-chemical", - "stimulant" - ], - "onset": "30-60 minutes.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "2-16 hours." - }, - "pretty_name": "3C-E", - "categories": [ - "psychedelic", - "research-chemical", - "stimulant" - ], - "formatted_dose": { - "Oral": { - "Threshold": "15-25mg", - "Light": "25-35mg", - "Common": "35-50mg", - "Strong": "50-70mg+" - } - }, - "formatted_duration": { - "value": "8-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_3CE.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal025.shtml" - }, - "formatted_aftereffects": { - "value": "2-16", - "_unit": "hours" - }, - "id": 185 - }, - "pv-8": { - "name": "pv-8", - "properties": { - "summary": "Stimulant of the pyrrolidinophenone class that is a higher homologue of α-PHP and generally less potent and less effective.", - "dose": "Light: 10-20mg Common: 20-40mg Strong: 40-60mg Heavy: 60+mg.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "aliases": [ - "a-phpp" - ], - "after-effects": "Oral: 6-12 hours | Insufflated: 4-8 hours | Vapourized: 2-5 hours.", - "onset": "Oral: 15-45 minutes. | Insufflated: 5-10 minutes | Vapourized: 1-2 minutes.", - "duration": "Oral: 3-6 hours | Insufflated: 2-5 hours. | Vapourized: 0.5-1.5 hours." - }, - "pretty_name": "PV-8", - "aliases": [ - "a-phpp" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-40mg", - "Strong": "40-60mg", - "Heavy": "60+mg." - } - }, - "formatted_duration": { - "Oral": "3-6", - "Insufflated": "2-5", - "Vapourized": "0.5-1.5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Insufflated": "5-10", - "Vapourized": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "6-12", - "Insufflated": "4-8", - "Vapourized": "2-5", - "_unit": "hours" - }, - "id": 186 - }, - "25ip-nbome": { - "name": "25ip-nbome", - "properties": { - "summary": "Almost unheard-of bomamine analogue of 2C-iP. Extremely potent psychedelic with stimulating qualities. May cause potentially dangerous vasoconstriction at high doses. May induce uncomfortable body load.", - "duration": "5-7 hours.", - "dose": "Sublingual Threshold: 250ug Light: 300-750ug Common: 750-1000ug Strong: 1000-1500ug", - "onset": "30-60 minutes.", - "aliases": [ - "25ip" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "test-kits": "Marquis: Red. | Mecke: Green. | Mandelin: Red and Green. | Froehde: Green. | Liebermann: Yellow > Brown. | Ehrlich: No colour change.", - "after-effects": "1-12 hours." - }, - "pretty_name": "25iP-NBOMe", - "aliases": [ - "25ip" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "250ug", - "Light": "300-750ug", - "Common": "750-1000ug", - "Strong": "1000-1500ug" - } - }, - "formatted_duration": { - "value": "5-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 187 - }, - "adinazolam": { - "name": "adinazolam", - "properties": { - "duration": "2-5 hours.", - "summary": "Benzodiazepine derivative that has some antidepressant properties. Never FDA approved, yet however has been sold as a research chemical.", - "onset": "10-25 minutes.", - "avoid": "All other CNS depressants.", - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "aliases": [ - "deracyn" - ], - "dose": "Light: 5-15mg Common: 15-30mg Strong: 30-50mg+", - "after-effects": "1-16 hours." - }, - "pretty_name": "Adinazolam", - "aliases": [ - "deracyn" - ], - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg+" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-25", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "id": 188 - }, - "pro-lad": { - "name": "pro-lad", - "properties": { - "summary": "A very rare lysergamide that is slightly less potent than LSD, yet with a shorter duration of action.", - "dose": "Light: 50-100ug Common: 100-150ug Strong: 150-200ug.", - "duration": "6-10 hours.", - "onset": "30-45 minutes.", - "categories": [ - "tentative", - "psychedelic" - ] - }, - "pretty_name": "PRO-LAD", - "categories": [ - "tentative", - "psychedelic" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100ug", - "Common": "100-150ug", - "Strong": "150-200ug." - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "id": 189 - }, - "5-meo-amt": { - "name": "5-meo-amt", - "properties": { - "duration": "Oral: 12-18 hours. | Insufflated: 8-12 hours.", - "dose": "Oral Threshold: 0.5-1mg Light: 1-2mg Common: 2-4mg Strong: 4-6mg | NOTE: Hospitalizations have occured with as doses as low as 8mg", - "onset": "30-120 minutes.", - "after-effects": "4-24+ hours.", - "summary": "A long-acting psychedelic and entactogenic tryptamine, related to aMT. Very potent and may be sold on blotters. Possibly has been missold as LSD in the past, however this is uncommon. Possibly an MAOI.", - "aliases": [ - "5meoamt" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "5-MeO-αMT", - "aliases": [ - "5meoamt" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Threshold": "0.5-1mg", - "Light": "1-2mg", - "Common": "2-4mg", - "Strong": "4-6mg" - } - }, - "formatted_duration": { - "Oral": "12-18", - "Insufflated": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeOAMT.shtml" - }, - "formatted_aftereffects": { - "value": "4-24+", - "_unit": "hours" - }, - "dose_note": " NOTE: Hospitalizations have occured with as doses as low as 8mg", - "id": 190 - }, - "methylone": { - "name": "methylone", - "properties": { - "summary": "βk-MDMA is a cathinone stimulant and empathogen, similar in structure to MDMA, though more stimulating and less empathogenic in comparison. Was very commonly mis-sold as MDMA on the street until it was banned in 2013. The Marquis reagent can differentiate βk-MDMA from MDMA. Less potent than MDMA with a slightly shorter duration.", - "duration": "2-4 hours", - "dose": "Oral Light: 100-150mg Common: 150-250mg Strong: 200-300mg Heavy: 300+mg", - "onset": "15-60 minutes", - "aliases": [ - "bk-mdma", - "m1", - "mdmc" - ], - "after-effects": "6-24 hours", - "marquis": "Yellow", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen", - "common" - ] - }, - "pretty_name": "Methylone", - "aliases": [ - "bk-mdma", - "m1", - "mdmc" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "100-150mg", - "Common": "150-250mg", - "Strong": "200-300mg", - "Heavy": "300+mg" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methylone.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal110.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Vibrating vision": "https://psychonautwiki.org/wiki/Vibrating_vision", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "id": 191 - }, - "2c-t-4": { - "name": "2c-t-4", - "properties": { - "summary": "A psychedelic phenethylamine that has a longer onset and duration compared to the more common 2C-T-x (2 and 7).", - "dose": "Oral Threshold: 5-6mg Light: 6-10mg Common: 10-15mg Strong: 15-20mg", - "onset": "30-120 minutes.", - "duration": "10-18 hours.", - "after-effects": "4-8 hours.", - "avoid": "MAOI's as the dangers with 2C-T-7 could also fall into this substance as well. (Serotonin Syndrome)", - "aliases": [ - "2ct4", - "2c-t4", - "2-ct4", - "2ct-4" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "test-kits": "Marquis: Pale Orange. | Mandelin: Orange (Or Purple). | Liebermann: Purple. | Ehrlich: Purple." - }, - "pretty_name": "2C-T-4", - "aliases": [ - "2ct4", - "2c-t4", - "2-ct4", - "2ct-4" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-6mg", - "Light": "6-10mg", - "Common": "10-15mg", - "Strong": "15-20mg" - } - }, - "formatted_duration": { - "value": "10-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CT4.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal041.shtml" - }, - "formatted_aftereffects": { - "value": "4-8", - "_unit": "hours" - }, - "id": 192 - }, - "4-aco-met": { - "name": "4-aco-met", - "properties": { - "onset": "20-40 minutes.", - "duration": "4-6 hours", - "after-effects": "2-12 hours.", - "dose": "Oral Light: 12-18mg Common: 20-25mg Heavy: 25-35+mg", - "aliases": [ - "metacetin", - "4-acetoxy-met", - "4acomet" - ], - "summary": "A rare psychedelic tryptamine which is thought to be metabolised into 4-HO-MET. Onset and duration, intensity will vary but effect profile is largely the same.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "4-AcO-MET", - "aliases": [ - "metacetin", - "4-acetoxy-met", - "4acomet" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "12-18mg", - "Common": "20-25mg", - "Heavy": "25-35+mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4AcOMET.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 193 - }, - "flunitrazolam": { - "name": "flunitrazolam", - "properties": { - "summary": "A very potent hypnotic Benzodiazepine. Triazolo version of Flunitrazepam.", - "duration": "4-5 hours", - "dose": "Threshold: 30-40ug Light: 40-80ug Common: 80-150ug Strong: 150-300ug.", - "avoid": "All other CNS depressants.", - "onset": "Oral: 10-30 minutes. | Sublingual: 5-15 minutes.", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming", - "tentative" - ], - "after-effects": "Oral: 1-16 hours. | Sublingual: 1-12 hours. | Note: This can be much longer on higher doses (Between 0.5-1mg after-effects can last up to around 36 hours)", - "aliases": [ - "fln" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Blackouts." - }, - "pretty_name": "Flunitrazolam", - "aliases": [ - "fln" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "30-40ug", - "Light": "40-80ug", - "Common": "80-150ug", - "Strong": "150-300ug." - } - }, - "formatted_duration": { - "value": "4-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "Sublingual": "5-15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Blackouts", - "" - ], - "formatted_aftereffects": { - "Oral": "1-16", - "Sublingual": "1-12", - "_unit": "hours" - }, - "id": 194 - }, - "indapex": { - "name": "indapex", - "properties": { - "summary": "5-MEO-TMT, one of Shulgin's lesser known creations. A psychedelic tryptamine little heard of outside of TiHKaL with very little known information about its effects on humans. May be particularly given to causing nausea.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "aliases": [ - "5-meo-tmt" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "duration": "5-10 hours.", - "onset": "20-50 minutes.", - "after-effects": "1-8 hours.", - "dose": "Oral Light: 60-75mg Common: 75-100mg Strong: 100-150mg. | Note: Very odd dosing curve. So be careful." - }, - "pretty_name": "Indapex", - "aliases": [ - "5-meo-tmt" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "60-75mg", - "Common": "75-100mg", - "Strong": "100-150mg." - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-50", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeOTMT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal45.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " Note: Very odd dosing curve. So be careful.", - "id": 195 - }, - "4-meo-mipt": { - "name": "4-meo-mipt", - "properties": { - "summary": "A rare psychedelic tryptamine first synthesised by Alexander Shulgin, said to the be \"little brother\" of 5-MeO-MiPT. Said to be relatively mild with lighter visual effects than most tryptamines.", - "duration": "3-7 hours", - "onset": "20-60 minutes", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "dose": "Oral Light: 10mg Common: 10-20mg Strong: 20+mg", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-4 hours." - }, - "pretty_name": "4-MeO-MiPT", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10mg", - "Common": "10-20mg", - "Strong": "20+mg" - } - }, - "formatted_duration": { - "value": "3-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4MeOMiPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal39.shtml" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 196 - }, - "paroxetine": { - "name": "paroxetine", - "properties": { - "categories": [ - "ssri" - ], - "aliases": [ - "paxil", - "seroxat" - ] - }, - "pretty_name": "Paroxetine", - "aliases": [ - "paxil", - "seroxat" - ], - "categories": [ - "ssri" - ], - "id": 197 - }, - "sinicuichi": { - "name": "sinicuichi", - "properties": { - "summary": "A perennial shrub with small narrow leaves and yellow flowers growing up to ~1.5 meters. Known under many different names. Has been used for Shamanic purposes by natives in Central America and Mexico. Mostly auditory based.", - "onset": "1-5 minutes.", - "duration": "15-45 minutes.", - "warning": "A fair amount of people after smoking this compound have reported to have fairly bad side-effects such as night fever, night sweats, and muscle pains.", - "aliases": [ - "sini", - "shrubby-yellowcrest", - "sun-opener", - "heimia-salicifolia", - "willow-leaf-heimia" - ], - "categories": [ - "psychedelic", - "tentative" - ] - }, - "pretty_name": "Sinicuichi", - "aliases": [ - "sini", - "shrubby-yellowcrest", - "sun-opener", - "heimia-salicifolia", - "willow-leaf-heimia" - ], - "categories": [ - "psychedelic", - "tentative" - ], - "formatted_duration": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "1-5", - "_unit": "minutes" - }, - "id": 198 - }, - "pentobarbital": { - "name": "pentobarbital", - "properties": { - "summary": "A CNS depressant drug that is of the barbituate class. Typically not used often as it is easier to OD on than benzodiazepines, the new alternative to barbituates. Used often for insomnia, to cause sedation.", - "dose": "Oral Light: 50-100mg Common: 100-200mg Heavy: 200-300mg | IM Light: 100-150mg Common: 150-200mg Heavy: 200mg+ | IV Light: 50-60mg Common: 60-100mg Heavy: 100mg+", - "aliases": [ - "nembutal", - "novopentobarb" - ], - "duration": "Oral 3-4 hours | IM 3-4 hours | IV 15-20 minutes", - "onset": "Oral 15-60 minutes | IM 10-25 minutes | IV 1 minute", - "avoid": "All other CNS depressants, also avoid if you have respiratory issues or liver issues as barbiturates are harsh on the liver.", - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "after-effects": "1-36 hours." - }, - "pretty_name": "Pentobarbital", - "aliases": [ - "nembutal", - "novopentobarb" - ], - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-200mg", - "Heavy": "200-300mg" - }, - "IM": { - "Light": "100-150mg", - "Common": "150-200mg", - "Heavy": "200mg+" - }, - "IV": { - "Light": "50-60mg", - "Common": "60-100mg", - "Heavy": "100mg+" - } - }, - "formatted_duration": { - "Oral": "3-4", - "IM": "3-4", - "IV": "15-20", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-60", - "IM": "10-25", - "IV": "1", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-36", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Information on summary duration onset and dosage: Page 930 - Nurse's drug handbook 14th edition Jones and Bartlett 2015" - ] - }, - "id": 199 - }, - "mexamine": { - "name": "mexamine", - "properties": { - "summary": "5-Methoxytryptamine, a tryptamine derivative that naturally occurs in the body at low levels. No evidence of recreational use. Apparently enhances dreams.", - "categories": [ - "psychedelic", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Mexamine", - "categories": [ - "psychedelic", - "tentative" - ], - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "id": 200 - }, - "3-fpm": { - "name": "3-fpm", - "properties": { - "onset": "Oral: 20-30 minutes | Insufflated: 1-5 minutes", - "duration": "Oral: 5-8 hours | Insufflated: 3-6 hours.", - "summary": "A functional stimulant related to phenmetrazine. Effects similar to amphetamine, but longer and more focused. Observed as being relatively benign in low doses, but seems to cause worrying health effects for heavy users. Pain from insufflation is eye-wateringly intense, but short.", - "dose": "Oral Threshold: 5-10mg Light: 10-25mg Common: 25-50mg Strong: 50-70mg. Heavy: 70-100mg | Insufflated Light: 10-20mg Common: 20-35mg Strong: 35-50mg Heavy: 50mg-70mg | NOTE: Repeated dosing appears to lengthen after-effects of sleeplessness / insomnia.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "aliases": [ - "3fpm", - "3-fph", - "3f-phenmetrazine", - "3f-p", - "3fp", - "pal-593" - ], - "effects": "increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "after-effects": "1-12 hours." - }, - "pretty_name": "3-FPM", - "aliases": [ - "3fpm", - "3-fph", - "3f-phenmetrazine", - "3f-p", - "3fp", - "pal-593" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-70mg.", - "Heavy": "70-100mg" - }, - "Insufflated": { - "Light": "10-20mg", - "Common": "20-35mg", - "Strong": "35-50mg", - "Heavy": "50mg-70mg" - } - }, - "formatted_duration": { - "Oral": "5-8", - "Insufflated": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-30", - "Insufflated": "1-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_3FPhenmetrazine.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Repeated dosing appears to lengthen after-effects of sleeplessness / insomnia.", - "id": 201 - }, - "phentermine": { - "name": "phentermine", - "properties": { - "dose": "Low: 15-20mg Common: 20-40mg Strong: 40-70mg's.", - "summary": "Psychostimulant of the substituted amphetamine class. Used in medicine as an appetite suppressant.", - "onset": "4-6 hours.", - "after-effects": "1-10 hours.", - "categories": [ - "stimulant", - "tentative" - ] - }, - "pretty_name": "Phentermine", - "categories": [ - "stimulant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Low": "15-20mg", - "Common": "20-40mg", - "Strong": "40-70mg" - } - }, - "formatted_onset": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "id": 202 - }, - "3c-p": { - "name": "3c-p", - "properties": { - "dose": "Oral Threshold: 5-10mg Light: 10-20mg Common: 20-40mg Heavy: 40+mg", - "duration": "10-18 hours", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "summary": "Rather new and uncommon stimulant, psychedelic and amphetamine with properties similar to the 2Cx class of drugs. 3-carbon homologue of proscaline.", - "onset": "60-150 minutes.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "3cp" - ], - "after-effects": "2-24 hours." - }, - "pretty_name": "3C-P", - "aliases": [ - "3cp" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Light": "10-20mg", - "Common": "20-40mg", - "Heavy": "40+mg" - } - }, - "formatted_duration": { - "value": "10-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-150", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_3CP.shtml" - }, - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 203 - }, - "3,4-ctmp": { - "name": "3,4-ctmp", - "properties": { - "summary": "A strong stimulant, NDRI and analogue of methylphenidate. Has increased in popularity in recent years. Said to be seven times more potent than methylphenidate but with a slower onset, however discrimination studies have found it to be more addictive than cocaine.", - "aliases": [ - "34ctmp", - "3,4-dichloromethylphenidate" - ], - "duration": "4-18 hours", - "onset": "30-90 minutes.", - "dose": "Oral Threshold: 1-2mg Light: 2-4mg Common: 4-6mg Heavy: 6-10mg", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "after-effects": "2-24 hours." - }, - "pretty_name": "3,4-CTMP", - "aliases": [ - "34ctmp", - "3,4-dichloromethylphenidate" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "1-2mg", - "Light": "2-4mg", - "Common": "4-6mg", - "Heavy": "6-10mg" - } - }, - "formatted_duration": { - "value": "4-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_34Dichloromethylphenidate.shtml" - }, - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 204 - }, - "4-mpd": { - "name": "4-mpd", - "properties": { - "summary": "Stimulant of the cathinone class. Higher homologue of Mephedrone, and the p-Methyl analogue of Pentedrone.", - "categories": [ - "tentative", - "stimulant", - "habit-forming" - ] - }, - "pretty_name": "4-MPD", - "categories": [ - "tentative", - "stimulant", - "habit-forming" - ], - "id": 205 - }, - "hydromorphone": { - "name": "hydromorphone", - "properties": { - "summary": "An opioid that is roughly 5x the potency of IV Morphine. Only comes in IR tablets in the US, and is given mostly as XR in other countries. It is frequently used in hospitals for short, but immediate pain relief during procedures requiring the patient to be awake. Also frequently used as a recreational opiate.", - "onset": "Oral 30-60 minutes | Insufflated 5-10 minutes | Intravenous 0-1 minutes", - "duration": "Oral: 3-4 hours | Insufflated: 2-3 hours | Intravenous: 1-2 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "dose": "Oral Light: 1-2mg Common: 3-4 Strong: 4-8mg+ | Insufflated Light: 1-2mg Common: 3-4mg Strong: 4-8mg+ | Intravenous Light: 1-2mg Common: 2-4mg Strong: 4-6mg+", - "aliases": [ - "dilaudid", - "diluadid" - ], - "bioavailability": "Oral 51.35% +/- 29.29% | Insufflated 52.4% | Rectal 36.33% +/- 29.6%", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil Constriction, Analgesia.", - "after-effects": "1-6 hours.", - "dose:": "Oral Light: 1-2mg Common: 3-4 Strong: 4-8mg+ | Insufflated Light: 1-2mg Common: 3-4mg Strong: 4-8mg+ | Intravenous Light: 1-2mg Common: 2-4mg Strong: 4-6mg+" - }, - "pretty_name": "Hydromorphone", - "aliases": [ - "dilaudid", - "diluadid" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "1-2mg", - "Common": "3-4", - "Strong": "4-8mg+" - }, - "Insufflated": { - "Light": "1-2mg", - "Common": "3-4mg", - "Strong": "4-8mg+" - }, - "Intravenous": { - "Light": "1-2mg", - "Common": "2-4mg", - "Strong": "4-6mg+" - } - }, - "formatted_duration": { - "Oral": "3-4", - "Insufflated": "2-3", - "Intravenous": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60", - "Insufflated": "5-10", - "Intravenous": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil Constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Hydromorphone.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 206 - }, - "5-methyl-bk-mdea": { - "name": "5-methyl-bk-mdea", - "properties": { - "summary": "Also known as 5-methyl ethylone or 5-ME, this is a cathinone drug and analogue of ethylone. Little is known about this obscure compound but it is reasonable to assume it has an effect profile similar to other stimulants of the cathionone class, with a slightly higher potency than ethylone. Potentially entactogenic and a monoamine releasing agent.", - "aliases": [ - "5-methyl-ethylone", - "5-me" - ], - "categories": [ - "stimulant", - "research-chemical" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "onset": "Oral: 20-40 minutes.", - "dose": "Oral Light: 50-100mg Common: 100-250mg Strong: 250-400mg+ | Insufflated Light: 30-60mg Common: 60-150mg Strong: 150-300mg+", - "duration": "Oral: 2-4 hours. | Insufflated: 2-3 hours." - }, - "pretty_name": "5-Methylethylone", - "aliases": [ - "5-methyl-ethylone", - "5-me" - ], - "categories": [ - "stimulant", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-250mg", - "Strong": "250-400mg+" - }, - "Insufflated": { - "Light": "30-60mg", - "Common": "60-150mg", - "Strong": "150-300mg+" - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "id": 207 - }, - "prazepam": { - "name": "prazepam", - "properties": { - "summary": "Benzodiazepine dervative. Has all the normal benzodiazepine-like quality (Anxiolytic/anticonvulsant/sedative/Skeletal muscle relaxant) It is also a prodrug for Desmethyldiazepam which is responsible for most if not all of the effects of Prazepam.", - "avoid": "All other CNS depressants, and Cimetidine", - "dose": "Light: 5-10mg Common: 10-20mg Strong: 20-40mg.", - "onset": "45-120 minutes.", - "after-effects": "8-24 hours.", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "aliases": [ - "centrac", - "centrax", - "demetrin", - "lysanxia", - "pozapam", - "prasepine", - "prazene", - "reapam", - "trepidan" - ], - "duration": "8-20 hours.", - "dose_to_diazepam": "Prazepam - 15mg ~=10mg Diazepam.", - "effects": "Anxiolytic, Anticonvulsant, Sedative, Skeletal Muscle Relaxant" - }, - "pretty_name": "Prazepam", - "aliases": [ - "centrac", - "centrax", - "demetrin", - "lysanxia", - "pozapam", - "prasepine", - "prazene", - "reapam", - "trepidan" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg." - } - }, - "formatted_duration": { - "value": "8-20", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Anticonvulsant", - "Sedative", - "Skeletal Muscle Relaxant" - ], - "formatted_aftereffects": { - "value": "8-24", - "_unit": "hours" - }, - "id": 208 - }, - "mephtetramine": { - "name": "mephtetramine", - "properties": { - "categories": [ - "research-chemical", - "tentative" - ], - "aliases": [ - "mtta" - ], - "summary": "Has a Phenpropylamine backbone like Methylphenidate. Seems barely active past negative physical effects. Only reports that include activity past the prior were mixing it with another substance.", - "warning": "Probably inactive. Please pm \"Hypnos\" if you have a trip report saying otherwise." - }, - "pretty_name": "Mephtetramine", - "aliases": [ - "mtta" - ], - "categories": [ - "research-chemical", - "tentative" - ], - "id": 209 - }, - "4-ho-det": { - "name": "4-ho-det", - "properties": { - "summary": "A rare compound first produced by Albert Hoffman, also known as ethocin. Structurally related to 4-HO-MET (metocin) and psilocin (4-HO-DMT), this drug has similar psychedelic effects but little recorded human usage. Probably similar to mushrooms. Potentially stimulating.", - "onset": "30-60 minutes.", - "dose": "Light: 10-15mg Common: 15-20mg Strong: 20-30mg+", - "duration": "3-7 hours.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "4hodet", - "4-hydroxy-det" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "4-HO-DET", - "aliases": [ - "4hodet", - "4-hydroxy-det" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "10-15mg", - "Common": "15-20mg", - "Strong": "20-30mg+" - } - }, - "formatted_duration": { - "value": "3-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4HODET.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal16.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 210 - }, - "4-fluoropentedrone": { - "name": "4-fluoropentedrone", - "properties": { - "summary": "An obscure analogue of pentedrone, little information exists about this cathinone. It is likely that it has the same general effects as pentedrone, mephedrone and other related stimulants.", - "aliases": [ - "4-fpd", - "4-f-pentedrone", - "4f-pentedrone" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ] - }, - "pretty_name": "4-Fluoropentedrone", - "aliases": [ - "4-fpd", - "4-f-pentedrone", - "4f-pentedrone" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "id": 211 - }, - "nicomorphine": { - "name": "nicomorphine", - "properties": { - "summary": "Opioid agonist that is 2-3x the potency of Morphine. Is used in few countries. Rapid onset of effects, due to the increased lipid solubility.", - "onset": "Oral: 15-30 minutes | Intravenously: 1-2 minutes.", - "duration": "Oral: 4-6 hours | Intravenously: 2-4 hours.", - "dose": "Oral Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg+", - "after-effects": "1-6 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ] - }, - "pretty_name": "Nicomorphine", - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "Oral": "4-6", - "Intravenously": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Intravenously": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 212 - }, - "don": { - "name": "don", - "properties": { - "summary": "A very rare psychedelic Amphetamine. That is more rough on the body then other DOx compounds. Making it physically painful in some cases.", - "onset": "30-120 minutes.", - "dose": "Threshold: 2mg Light: 3mg Common: 3-5mg Heavy: 5mg+ | NOTE: These doses are tentative and may need further research.", - "duration": "14-22 hours.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "after-effects": "12-24 hours", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "DON", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "2mg", - "Light": "3mg", - "Common": "3-5mg", - "Heavy": "5mg+" - } - }, - "formatted_duration": { - "value": "14-22", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DON.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal070.shtml" - }, - "formatted_aftereffects": { - "value": "12-24", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 213 - }, - "2-fa": { - "name": "2-fa", - "properties": { - "summary": "Stimulant drug of the amphetamine family. Reported as having effects similar to those of Dextroamphetamine, but with a milder euphoria and a comparatively smoother comedown. Has a shorter duration and less empathogenic effect-profile as compared with 4-FA. Thought to produce less neurotoxic metabolites compared to amphetamine.", - "dose": "Oral Light: 5-15mg Common: 15-30mg Strong: 30-50mg Heavy: 50mg+ | Note: Insufflating does not appear to raise the bioavailability than oral ingestion, and can cause damage to nasal cavities.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "onset": "Oral: 15-20 minutes | Insufflated: 2-5 minutes", - "duration": "Oral: 3-5 hours | Insufflated: 1-2 hours", - "aliases": [ - "2-fluoroamphetamine", - "2-fmp", - "2fa" - ], - "after-effects": "2-12 hours." - }, - "pretty_name": "2-FA", - "aliases": [ - "2-fluoroamphetamine", - "2-fmp", - "2fa" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg", - "Heavy": "50mg+" - } - }, - "formatted_duration": { - "Oral": "3-5", - "Insufflated": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-20", - "Insufflated": "2-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2Fluoroamphetamine.shtml" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "dose_note": " Note: Insufflating does not appear to raise the bioavailability than oral ingestion, and can cause damage to nasal cavities.", - "id": 214 - }, - "secobarbital": { - "name": "secobarbital", - "properties": { - "summary": "A Barbiturate derivative that possesses all the classic effects of todays Benzodiazepines, and the old Barbiturates. It's used in the treatment of Epilepsy, short term treatment for insomnia, and a preoperative medication for anaesthesia and anxiolysis for short surgical/diagnostic/therapeutic procedures.", - "aliases": [ - "seconal" - ], - "onset": "15-30 minutes.", - "duration": "6-10 hours.", - "after-effects": "1-24 hours.", - "dose": "Oral Light: 25-50mg Common: 50-150mg Strong: 150-300mg", - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "avoid": "All other CNS depressants." - }, - "pretty_name": "Secobarbital", - "aliases": [ - "seconal" - ], - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50mg", - "Common": "50-150mg", - "Strong": "150-300mg" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 215 - }, - "4-cbc": { - "name": "4-cbc", - "properties": { - "summary": "Is a potentially very neurotoxic Cathinone. Obviously no scientic reports have been noted on the neurotoxicity or cardiotoxicity, so please move on with extreme caution.", - "dose": "Oral Light: 40-70mg Common: 70-100mg Strong: 100-130mg | Insufflated: Light: 30-50mg Common: 50-80mg Strong: 80-100mg. | Note: Be careful and read the summary before ingesting this substance.", - "onset": "Oral: 30-60mg | Insufflated: 5-20 minutes.", - "duration": "Oral: 2-4 hours. | Insufflated: 1-3 hours.", - "after-effects": "2-6 hours.", - "categories": [ - "stimulant", - "research-chemical", - "empathogen", - "habit-forming" - ], - "avoid": "Other stimulants, pretty much everything that can raise your blood pressure." - }, - "pretty_name": "4-CBC", - "categories": [ - "stimulant", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "40-70mg", - "Common": "70-100mg", - "Strong": "100-130mg" - }, - "Insufflated:": { - "Insufflated": "Light", - "Common": "50-80mg", - "Strong": "80-100mg." - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60mg", - "Insufflated": "5-20", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "dose_note": " Note: Be careful and read the summary before ingesting this substance.", - "id": 216 - }, - "6-eapb": { - "name": "6-eapb", - "properties": { - "summary": "A rare entactogen benzofuran structurally related to MDMA and 6-APB, though weaker in effects. the pharmacology of this compound is unclear. Likely to be a monoamine releaser, monoamine reuptake inhibitor or both.", - "onset": "20-40 minutes.", - "duration": "4-7~ hours.", - "after-effects": "1-10 hours.", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "dose": "Light: 50-75mg Common: 75-100mg Strong: 100-150mg+" - }, - "pretty_name": "6-EAPB", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-75mg", - "Common": "75-100mg", - "Strong": "100-150mg+" - } - }, - "formatted_duration": { - "value": "4-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "id": 217 - }, - "isophenmetrazine": { - "name": "isophenmetrazine", - "properties": { - "dose": "Oral Light: 5-10mg Common: 10-20mg Strong: 20-50mg+ | Insufflated Light: 2-5mg Common: 5-15mg Strong: 20-40mg+", - "duration": "Oral: 3-5 hours. Insufflated: 2-4 hours.", - "onset": "Oral: 15-30 minutes. Insufflated: 5-10 minutes.", - "avoid": "Other stimulants.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "summary": "Rare and little known analogue of phenmetrazine, which is slightly more potent than other analogues. Probably a stimulating, appetite supressing drug with high addiction potential. Potentially a dopamine and/or norepinephrine releasing agent.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Isophenmetrazine", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-50mg+" - }, - "Insufflated": { - "Light": "2-5mg", - "Common": "5-15mg", - "Strong": "20-40mg+" - } - }, - "formatted_duration": { - "Oral": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 218 - }, - "5-ppdi": { - "name": "5-ppdi", - "properties": { - "summary": "An obscure analogue of α-PBP, which is itself an analogue of α-PVP. This rare compound has little history of human usage. Some trip reports suggest it is inactive. If it is active it likely has a similar effect profile to other pyrovalerone stimulants.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "dose": "Light: 15-30mg Common: 30-50mg Strong: 50-70mg Heavy: 70+mg.", - "onset": "Oral: 10-30 minutes. Insufflated 5-10 minutes.", - "duration": "Oral: 3-6 hours. Insufflated 1-4 hours.", - "after-effects": "3-6 hours." - }, - "pretty_name": "5-PPDI", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "15-30mg", - "Common": "30-50mg", - "Strong": "50-70mg", - "Heavy": "70+mg." - } - }, - "formatted_duration": { - "Oral": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "3-6", - "_unit": "hours" - }, - "id": 219 - }, - "methylphenidate": { - "name": "methylphenidate", - "properties": { - "dose": "Oral Light: 20-40mg Common: 40-60mg Strong: 60-80mg Heavy: 80-100mg+ | Insufflated Light: 5-15mg Common: 15-40mg Strong: 40-60mg Heavy: 60-75mg+", - "aliases": [ - "mph", - "ritalin", - "concerta", - "biphentin" - ], - "summary": "A psychostimulant commonly used in the treatment of ADHD, narcolepsy and obesity, particularly in the EU instead of Adderall. Methylphenidate is also a 5HT1A receptor agonist. Sometimes prescribed off-label to help the withdrawals from cocaine and other stimulants.", - "effects": "Increased alertness, Euphoria, Increased motivation, Reduced appetite, Flushing of the face, Increased body temperature, Tachycardia (Increased heart rate) Paranoia, Insomnia.", - "onset": "Oral-IR: 30-120 minutes | Oral-XR: 30-120 minutes | Insufflated-XR: 5-10 minutes | Insufflated-IR: 5-10 minutes", - "marquis": "Moderate orange yellow ", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "duration": "Oral-IR: 3-6 hours. | Oral-XR: 8-12 hours. | Insufflated: 2-4 hours. | Note: XR formulations become IR before they can be insufflated, so duration should be mostly the same.", - "after-effects": "1-24 hours." - }, - "pretty_name": "Methylphenidate", - "aliases": [ - "mph", - "ritalin", - "concerta", - "biphentin" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "20-40mg", - "Common": "40-60mg", - "Strong": "60-80mg", - "Heavy": "80-100mg+" - }, - "Insufflated": { - "Light": "5-15mg", - "Common": "15-40mg", - "Strong": "40-60mg", - "Heavy": "60-75mg+" - } - }, - "formatted_duration": { - "Oral-IR": "3-6", - "Oral-XR": "8-12", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral-IR": "30-120", - "Oral-XR": "30-120", - "Insufflated-XR": "5-10", - "Insufflated-IR": "5-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Increased alertness", - "Euphoria", - "Increased motivation", - "Reduced appetite", - "Flushing of the face", - "Increased body temperature", - "Tachycardia (Increased heart rate) Paranoia", - "Insomnia", - "" - ], - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought organization": "https://psychonautwiki.org/wiki/Thought_organization", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "A chemical ionization selected ion monitoring assay for methylphenidate and ritalinic acid - http://www.ncbi.nlm.nih.gov/pubmed/526558", - "Panlobular pulmonary emphysema caused by i.v. injection of methylphenidate (Ritalin): findings on chest radiographs and CT scans. - http://www.ncbi.nlm.nih.gov/pubmed/8109495", - "Ethylphenidate formation in human subjects after the administration of a single dose of methylphenidate and ethanol. - https://www.ncbi.nlm.nih.gov/pubmed/10820132", - "A comparison of methylphenidate-, amphetamine-, and methamphetamine-induced hyperthermia and neurotoxicity in male Sprague-Dawley rats during... - https://www.ncbi.nlm.nih.gov/pubmed/22289608", - "Methylphenidate and brain dopamine neurotoxicity. - http://www.ncbi.nlm.nih.gov/pubmed/9365033", - "Methylphenidate treatment induces oxidative stress in young rat brain. - http://www.ncbi.nlm.nih.gov/pubmed/16494852", - "A comprehensive in vitro screening of d-, l-, and dl-threo-methylphenidate: an exploratory study. - http://www.ncbi.nlm.nih.gov/pubmed/17201613", - "Methylphenidate and its ethanol transesterification metabolite ethylphenidate: brain disposition, monoamine transporters and motor activity. - http://www.ncbi.nlm.nih.gov/pubmed/17218796", - "The psychostimulant d-threo-(R,R)-methylphenidate binds as an agonist to the 5HT(1A) receptor. - http://www.ncbi.nlm.nih.gov/pubmed/19322953", - "Methylphenidate combined with aripiprazole in children and adolescents with bipolar disorder and attention-deficit/hyperactivity disorder - http://www.ncbi.nlm.nih.gov/pubmed/19877980", - "Isopropylphenidate: an ester homolog of methylphenidate with sustained and selective dopaminergic activity and reduced drug interaction - http://www.ncbi.nlm.nih.gov/pubmed/24261661", - "Object memory impairment at post-drug Day 15 but not at Day 1 after a regimen of repeated treatment with oral methylphenidate. - http://www.ncbi.nlm.nih.gov/pubmed/24631430", - "Long Withdrawal of Methylphenidate Induces a Differential Response of the Dopaminergic System and Increases Sensitivity to Cocaine in the Prefrontal Cortex of Spontaneously Hypertensive Rats. - http://www.ncbi.nlm.nih.gov/pubmed/26509840", - "A chemical ionization selected ion monitoring assay for methylphenidate and ritalinic acid. - http://www.ncbi.nlm.nih.gov/pubmed/526558", - "A comparison of methylphenidate-, amphetamine-, and methamphetamine-induced hyperthermia and neurotoxicity in male Sprague-Dawley rats during the w... - https://www.ncbi.nlm.nih.gov/pubmed/22289608", - "Methylphenidate and brain dopamine neurotoxicity. - https://www.ncbi.nlm.nih.gov/pubmed/9365033", - "Methylphenidate combined with aripiprazole in children and adolescents with bipolar disorder and attention-deficit/hyperactivity disorder: a random... - http://www.ncbi.nlm.nih.gov/pubmed/19877980", - "Long Withdrawal of Methylphenidate Induces a Differential Response of the Dopaminergic System and Increases Sensitivity to Cocaine in the Prefronta... - http://www.ncbi.nlm.nih.gov/pubmed/26509840", - "IV use of methylphenidate can lead to infections and abscesses due to the fillers in the medication - http://onlinelibrary.wiley.com/doi/10.1002/hed.2890060409/full", - "Pregnancy category C according to the FDA - http://www.accessdata.fda.gov/drugsatfda_docs/label/2007/010187s069,018029s040,021284s011lbl.pdf" - ] - }, - "id": 220 - }, - "2-dpmp": { - "name": "2-dpmp", - "properties": { - "aliases": [ - "desoxypipradrol", - "2dpmp", - "2-desoxypiperadol", - "desoxypipradol" - ], - "dose": "Oral Threshold: 1-2mg Light: 2-4mg Common: 4-6mg Strong: 6-8mg | Insufflated Threshold: 1-2mg Light: 2-3mg Common: 3-4mg Strong: 4-6mg | NOTE: This drug is extremely potent and extremely long lasting, even at 'common' doses. Be sure to start low and avoid redosing.", - "duration": "16-72 hours", - "onset": "60-120 minutes.", - "summary": "A very potent stimulant that is a NDRI. Developed by Novartis in the 1950s, to treat narcolepsy and ADHD, however dropped when Methylphenidate was produced a few years later, which was seen as superior due to its shorter T½. 2-DPMP Half life 16-20 hours. Warning: subjective reports suggest this drug is caustic to the nasal mucosa and may cause damage to the nasal cavity.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "warning": "Due to the long half life (16-20 hours) redosing is strongly recommended against.", - "half-life": "16-20 hours.", - "after-effects": "1-72 hours." - }, - "pretty_name": "2-DPMP", - "aliases": [ - "desoxypipradrol", - "2dpmp", - "2-desoxypiperadol", - "desoxypipradol" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "1-2mg", - "Light": "2-4mg", - "Common": "4-6mg", - "Strong": "6-8mg" - }, - "Insufflated": { - "Threshold": "1-2mg", - "Light": "2-3mg", - "Common": "3-4mg", - "Strong": "4-6mg" - } - }, - "formatted_duration": { - "value": "16-72", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Desoxypipradrol_.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal052.shtml" - }, - "formatted_aftereffects": { - "value": "1-72", - "_unit": "hours" - }, - "dose_note": " NOTE: This drug is extremely potent and extremely long lasting, even at 'common' doses. Be sure to start low and avoid redosing.", - "id": 221 - }, - "4-fluoromethylphenidate": { - "name": "4-fluoromethylphenidate", - "properties": { - "summary": "A relatively uncommon, more serotonergic RC derivative of methylphenidate. A dopamine reuptake inhibitor possessing similar effects to associated stimulant compounds.", - "dose": "Oral Threshold: 1-5mg Light: 5-10mg Common: 10-15mg Strong: 15-20mg Heavy: 20-25mg | Note: There has been a range of different reactions to similar doses, particularly some users have reported 15mg being too intense. It is advisable to start low with this drug.", - "duration": "4-8 hours", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "4f-mph", - "4-fmph", - "4fmph", - "4-fl-mph", - "4-fluoro-mph" - ], - "after-effects": "5-10 hours", - "onset": "25-40 minutes" - }, - "pretty_name": "4-Fluoromethylphenidate", - "aliases": [ - "4f-mph", - "4-fmph", - "4fmph", - "4-fl-mph", - "4-fluoro-mph" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "1-5mg", - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-20mg", - "Heavy": "20-25mg" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "25-40", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "5-10", - "_unit": "hours" - }, - "dose_note": " Note: There has been a range of different reactions to similar doses, particularly some users have reported 15mg being too intense. It is advisable to start low with this drug.", - "id": 222 - }, - "5-mapb": { - "name": "5-mapb", - "properties": { - "onset": "45-60 minutes", - "dose": "Oral Light: 40-60mg Common: 60-80mg Heavy: 80-100mg+", - "duration": "5-8 hours", - "after-effects": "2-4 hours", - "summary": "An empathogen structurally similar to MDMA. Typically more visual than MDMA. Often reported to be much less stimulating and more relaxing than most other stimulating empathogens. Less psychedelic than 6-APB. Much longer lasting than MDMA.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "empathogen", - "habit-forming" - ], - "aliases": [ - "5mapb" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "5-MAPB", - "aliases": [ - "5mapb" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "40-60mg", - "Common": "60-80mg", - "Heavy": "80-100mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MAPB.shtml" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 223 - }, - "doi": { - "name": "doi", - "properties": { - "dose": "Oral Threshold: 500-750ug. Light: 750ug-1mg. Common: 1mg-3mg. Heavy: 3mg+", - "onset": "60-90 minutes", - "summary": "A potent, long-acting psychedelic stimulant. Historically, it has rarely been consumed deliberately, but occasionally sold as LSD. However, it has recently found its own little nest in the research chemical community.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "duration": "12-18 hours (widely dependant on dose)", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-24 hours." - }, - "pretty_name": "DOI", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "500-750ug.", - "Light": "750ug-1mg.", - "Common": "1mg-3mg.", - "Heavy": "3mg+" - } - }, - "formatted_duration": { - "value": "12-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DOI.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal067.shtml" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 224 - }, - "metaclazepam": { - "name": "metaclazepam", - "properties": { - "summary": "A benzodiazepine derivative. Which is mostly an anxiolytic substance, without strong hypnotic properties that most benzodiazepines have. Its active metabolite is N-desmethylmetaclazepam, which is the main metabolite. Slightly more effective as an anxiolytic than Bromazepam.", - "dose": "Oral Light: 9.5mg-18.75mg's. Common: 18.75mg's-35mg Strong: 35-50mg+", - "onset": "duration 6-16 hours.", - "after-effects": "1-24 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "habit-forming", - "tentative", - "depressant" - ] - }, - "pretty_name": "Metaclazepam", - "categories": [ - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "9.5mg-18.75mg", - "Common": "18.75mg", - "Strong": "35-50mg+" - } - }, - "formatted_onset": { - "value": "duration", - "_unit": "hours" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 225 - }, - "3-ho-pcp": { - "name": "3-ho-pcp", - "properties": { - "duration": "3-4 hours", - "onset": "20-40 minutes", - "aliases": [ - "3hopcp" - ], - "summary": "An arylcyclohexamine dissociative analogue of PCP, this drug is relatively uncommon, and little information is available. It is reported to not only have dissociative activity but also be an opioid. Some trip reports suggest very negative side-effects including intense muscle tension.", - "dose": "Oral Threshold: ~2mg Light: 2-4mg Common: 4-5mg Strong: 5+mg", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "after-effects": "2 hours to a month." - }, - "pretty_name": "3-HO-PCP", - "aliases": [ - "3hopcp" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "2-4mg", - "Common": "4-5mg", - "Strong": "5+mg" - } - }, - "formatted_duration": { - "value": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2", - "_unit": "hours" - }, - "id": 226 - }, - "dipt": { - "name": "dipt", - "properties": { - "summary": "A rare tryptamine psychedelic closely related to DMT, with the interesting property of having little visual hallucinations, but strong auditory effects.", - "aliases": [ - "diisopropyltryptamine" - ], - "dose": "Threshold: 15mg Light: 15-25mg Common: 30-50mg Heavy: 50mg+ | NOTE: This is a very new substance with very little history of human use. Start low and work your way up, doses are not to be taken as reccomended values.", - "onset": "30-60 minutes.", - "duration": "3-5 hours", - "after-effects": "12-24 hours", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "DiPT", - "aliases": [ - "diisopropyltryptamine" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "15mg", - "Light": "15-25mg", - "Common": "30-50mg", - "Heavy": "50mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DiPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal04.shtml" - }, - "pweffects": { - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Inner ear pressure": "https://psychonautwiki.org/wiki/Inner_ear_pressure", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Stomach bloating": "https://psychonautwiki.org/wiki/Stomach_bloating", - "Thought suppression": "https://psychonautwiki.org/wiki/Thought_suppression" - }, - "formatted_aftereffects": { - "value": "12-24", - "_unit": "hours" - }, - "dose_note": " NOTE: This is a very new substance with very little history of human use. Start low and work your way up, doses are not to be taken as reccomended values.", - "id": 227 - }, - "25n-nbome": { - "name": "25n-nbome", - "properties": { - "dose": "Sublingual/Buccal Light: 100-300ug Common: 300-800ug Strong: 800-1300ug+", - "summary": "A rare, highly potent and yellow psychedelic phenethylamine and derivative of 2C-N. Effects are similar to other NBOMe compounds, with hallucinations, intense body load, stimulation and vasoconstriction. At high doses vasoconstriction can be dangerous, exercise caution.", - "duration": "5-10 hours.", - "onset": "45-75 minutes.", - "aliases": [ - "2-c-n-nbome", - "25n" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-12 hours.", - "test-kits": "Marquis: Red > Brown. | Mecke: Blue > Black. | Mandelin: Blue > Black. | Froehde: Brown. | Liebermann: Brown. | Simon's: Red > Brown. | Ehrlich: No colour change." - }, - "pretty_name": "25N-NBOMe", - "aliases": [ - "2-c-n-nbome", - "25n" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Sublingual/Buccal": { - "Light": "100-300ug", - "Common": "300-800ug", - "Strong": "800-1300ug+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-75", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 228 - }, - "prolintane": { - "name": "prolintane", - "properties": { - "summary": "A stimulant drug which is a dopamine reuptake inhibitor, related to MDPV and Pyrovalerone. It was first developed in the 1950s, and has seen some light usage in rave culture, though it remains relatively uncommon. Believed to have a relatively forgiving safety profile.", - "dose": "Threshold: 5-10mg Light: 10-15 Common: 15-30mg Strong: 30-50mg+", - "onset": "15-30 minutes.", - "duration": "3-6 hours (Highly dependant on dose)", - "avoid": "Other stimulants.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "after-effects": "1-4 hours.", - "aliases": [ - "catovit", - "promotil", - "villescon" - ] - }, - "pretty_name": "Prolintane", - "aliases": [ - "catovit", - "promotil", - "villescon" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Light": "10-15", - "Common": "15-30mg", - "Strong": "30-50mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 229 - }, - "nitemazepam": { - "name": "nitemazepam", - "properties": { - "summary": "A new RC benzodiazepine based off the chemical structure of Nimetazepam. It is relatively new and not many experience reports exist on it. It is expected to feel similar to temazepam.", - "aliases": [ - "3-hydroxynimetazepam" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming", - "tentative" - ], - "onset": "15-45 minutes.", - "duration": "6-12 hours.", - "after-effects": "1-12 hours.", - "dose": "Light: 1-1.5mg Common: 1.5-3mg Strong: 3-5mg+" - }, - "pretty_name": "Nitemazepam", - "aliases": [ - "3-hydroxynimetazepam" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "1-1.5mg", - "Common": "1.5-3mg", - "Strong": "3-5mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 230 - }, - "lormetazepam": { - "name": "lormetazepam", - "properties": { - "summary": "Relatively rare prescription benzodiazepine. Short acting with a short half life. Generally only seen in the Netherlands. Sedative, hypnotic and anxiolytic.", - "onset": "10-30 minutes.", - "duration": "4-8 hours. (Dependant on dose)", - "after-effects": "1-24 hours (Heavily dependant on dose)", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "avoid": "All other CNS depressants.", - "dose": "Light: 0.5-1mg Common: 1-2mg Strong: 2-4mg.", - "bioavailability": "Oral: 80%.", - "dose_to_diazepam": "Lormetazepam - 1-2mg's ~=10mg Diazepam.", - "aliases": [ - "noctamid" - ] - }, - "pretty_name": "Lormetazepam", - "aliases": [ - "noctamid" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg." - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 231 - }, - "picamilon": { - "name": "picamilon", - "properties": { - "summary": "An analogue of GABA that does pass the brain blood barrier, which is then hydrolyzed into GABA and Niacin. In which the GABA could produce an anxiolytic effect. The Niacin as a vasodilator. And is usually used as part of a nootropic stack.", - "onset": "10-45 minutes.", - "duration": "2-4 hours.", - "dose": "Oral Light: 40-80mg Common: 80-140mg Strong: 140-250mg.", - "categories": [ - "nootropic", - "depressant", - "habit-forming" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Picamilon", - "categories": [ - "nootropic", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "40-80mg", - "Common": "80-140mg", - "Strong": "140-250mg." - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Picamilon.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 232 - }, - "methamphetamine": { - "name": "methamphetamine", - "properties": { - "effects": "increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness, fatal kidney disorder, possible brain damage liver damage.", - "dose": "Oral Light: 5-10mg Common: 10-30mg Strong: 20-40mg Heavy: 40-100mg | Insufflated Light: 5-10mg Common: 10-30mg Strong: 30-50mg Heavy: 50mg+ | Smoked Light: 5-10mg Common: 10-20mg Strong: 30-60mg Heavy: 50mg+ | IV Light: 5-10mg Common: 10-20mg Strong: 20-40mg Heavy: 40mg+", - "onset": "Oral: 20-70 minutes | Insufflated: 5-10 minutes | Smoked: 0-2 minutes | IV: 0-2 minutes", - "duration": "Oral: 10-12 hours | Insufflated: 8-10 hours | Smoked: 3-8 hours | IV: 6-10 hours *NOTE: Check ~after-effects*", - "after-effects": "24 hours for all routes of administration. After effects may last longer if a user redoses.", - "summary": "A fairly common and very strong CNS stimulant. It is sometimes prescribed in the form of desoxyn for ADHD and severe obesity. In low doses, methamphetamine can elevate mood, increase alertness, concentration, energy and reduces appetite. At higher doses, it can induce mania, psychosis and muscle degeneration among other issues. Tolerant users may report much higher doses than new users.", - "aliases": [ - "meth", - "desoxyn", - "tik" - ], - "marquis": "Deep reddish orange - Dark reddish brown", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "avoid": "Rinsing mouth with mouthwash high in alcohol due to drying effects; using sugar filled chewing gum; usage within 14 days of MAOI - Also: Just avoid meth in the first place. Please.", - "bioavailability": "Oral 55-62.7% | Insufflated 75-80% | Vapourized 67-90.3%." - }, - "pretty_name": "Methamphetamine", - "aliases": [ - "meth", - "desoxyn", - "tik" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-30mg", - "Strong": "20-40mg", - "Heavy": "40-100mg" - }, - "Insufflated": { - "Light": "5-10mg", - "Common": "10-30mg", - "Strong": "30-50mg", - "Heavy": "50mg+" - }, - "Smoked": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "30-60mg", - "Heavy": "50mg+" - }, - "IV": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg", - "Heavy": "40mg+" - } - }, - "formatted_duration": { - "Oral": "10-12", - "Insufflated": "8-10", - "Smoked": "3-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-70", - "Insufflated": "5-10", - "Smoked": "0-2", - "IV": "0-2", - "_unit": "minutes" - }, - "formatted_effects": [ - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "fatal kidney disorder", - "possible brain damage liver damage", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methamphetamine.shtml" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Body odor alteration": "https://psychonautwiki.org/wiki/Body_odor_alteration", - "Bronchodilation": "https://psychonautwiki.org/wiki/Bronchodilation", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Ego inflation": "https://psychonautwiki.org/wiki/Ego_inflation", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temporary erectile dysfunction": "https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought organization": "https://psychonautwiki.org/wiki/Thought_organization", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Comparison of intranasal methamphetamine and d-amphetamine self-administration by humans. -https://www.ncbi.nlm.nih.gov/pubmed/22050030", - "Methamphetamine or desoxyn should not be used within 14 days of using a MAOI drug - Mosby's Dental Drug Reference Ninth Edition 2010", - "Meth/desoxyn usage for long periods of time in children or people who have not finished growing will cause temporary suppression of weight and height growth - Mosby's Dental Drug Reference 9th Ed. 2010" - ] - }, - "id": 233 - }, - "o-pce": { - "name": "o-pce", - "properties": { - "summary": "Dissociative of the Arylcyclohexylamine class. Structurally related to Deschloroketamine.", - "duration": "Oral 3-6 hours. | Insufflated 2-5 hours.", - "onset": "Oral 25-75 minutes. | Insufflated 15-45 minutes.", - "dose": "Oral Light: 3-6mg Common: 6-11mg Strong: 10-20mg. Insufflated Light: 3-5mg Common: 5-10mg Strong: 10-20mg.", - "after-effects": "2-48 hours.", - "avoid": "CNS depressants.", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "2'-oxo-pce", - "eticyclidone", - "opce", - "2-oxo-pce" - ] - }, - "pretty_name": "O-PCE", - "aliases": [ - "2'-oxo-pce", - "eticyclidone", - "opce", - "2-oxo-pce" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "3-5mg", - "Common": "5-10mg", - "Strong": "10-20mg." - } - }, - "formatted_duration": { - "Oral": "3-6", - "Insufflated": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "25-75", - "Insufflated": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-48", - "_unit": "hours" - }, - "id": 234 - }, - "4-aco-dalt": { - "name": "4-aco-dalt", - "properties": { - "dosage": "(Very Tentative)Orally Threshold: 20mg Light: 40-50mg Common: 50-70mg Heavy: 100mg+ Smoked Threshold: 2-4mg Light: 5-8mg Common: 10-15mg Strong: 15mg+", - "onset": "30-90 minutes.", - "duration": "5-9 hours.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "summary": "An uncommon tryptamine derivative first reported in the mid 2000s, likely a psychedelic. Little is known about the pharmacology or effects of this compound.", - "dose": "Oral Threshold: 20mg Light: 40-50mg Common: 50-70mg Heavy: 100+mg | Vaporized Threshold: 2-4mg Light: 5-8mg Common: 10-15mg Strong: 15+mg", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "4acodalt" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "4-AcO-DALT", - "aliases": [ - "4acodalt" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "20mg", - "Light": "40-50mg", - "Common": "50-70mg", - "Heavy": "100+mg" - }, - "Vaporized": { - "Threshold": "2-4mg", - "Light": "5-8mg", - "Common": "10-15mg", - "Strong": "15+mg" - } - }, - "formatted_duration": { - "value": "5-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4AcODALT.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 235 - }, - "amt": { - "name": "amt", - "properties": { - "summary": "A long-acting psychedelic-empathogen with a broad method of action in the brain. Not suitable for combination with many other substances. Used as an anti-depressant in the Soviet Union, but later found popularity in the RC scene, mainly in the UK.", - "aliases": [ - "Alpha-methyltryptamine", - "alpha-methyltryptamine", - "alphamethyltryptamine", - "indopan", - "monase" - ], - "dose": "Oral Light: 15-25mg Common: 25-40mg Strong: 40-60mg Heavy: 60mg+", - "onset": "30-90 minutes", - "duration": "10-16 hours", - "avoid": "Other MAOIs http://www.erowid.org/chemicals/maois/maois_info3.shtml", - "detection": "Not tested for in standard drug tests.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "after-effects": "6-12 hours", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "αMT", - "aliases": [ - "Alpha-methyltryptamine", - "alpha-methyltryptamine", - "alphamethyltryptamine", - "indopan", - "monase" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "15-25mg", - "Common": "25-40mg", - "Strong": "40-60mg", - "Heavy": "60mg+" - } - }, - "formatted_duration": { - "value": "10-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_AMT.shtml" - }, - "formatted_aftereffects": { - "value": "6-12", - "_unit": "hours" - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Dangerous" - }, - "dox": { - "status": "Dangerous" - }, - "nbomes": { - "status": "Dangerous" - }, - "2c-x": { - "status": "Dangerous" - }, - "2c-t-x": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Dangerous" - }, - "cannabis": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Small amounts can reduce nausea with aMT but take care." - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Dangerous" - }, - "dxm": { - "status": "Dangerous" - }, - "pcp": { - "status": "Dangerous" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Dangerous" - }, - "mdma": { - "status": "Dangerous" - }, - "cocaine": { - "status": "Dangerous" - }, - "caffeine": { - "status": "Caution", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort." - }, - "alcohol": { - "status": "Caution", - "note": "aMT has a broad mechanism of action in the brain and so does alcohol so the combination can be unpredictable" - }, - "ghb/gbl": { - "status": "Low Risk & Decrease" - }, - "opioids": { - "status": "Low Risk & No Synergy", - "note": "No unexpected interactions" - }, - "tramadol": { - "status": "Dangerous" - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Dangerous", - "note": "aMT is an MAOI on its own. Using enzyme inhibitors can greatly reduce predictability of effects." - }, - "ssris": { - "status": "Dangerous" - } - }, - "id": 236 - }, - "isopropylphenidate": { - "name": "isopropylphenidate", - "properties": { - "summary": "IPPH (or incorrectly IPH) is a novel piperidine based methylphenidate analogue and NDRI stimulant, but comes with much less physical side effects.", - "duration": "3-6 hours", - "onset": "<30 minutes.", - "dose": "Light: 7-10mg Common: 10-15mg Strong: 15-30mg+", - "aliases": [ - "iph", - "ipph", - "ippd", - "ipp" - ], - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "stimulant" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Isopropylphenidate", - "aliases": [ - "iph", - "ipph", - "ippd", - "ipp" - ], - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "stimulant" - ], - "formatted_dose": { - "Oral": { - "Light": "7-10mg", - "Common": "10-15mg", - "Strong": "15-30mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Isopropylphenidate.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Isopropylphenidate: an ester homolog of methylphenidate with sustained and selective dopaminergic activity and reduced drug interaction liability. - http://www.ncbi.nlm.nih.gov/pubmed/24261661" - ] - }, - "id": 237 - }, - "methoxyketamine": { - "name": "methoxyketamine", - "properties": { - "summary": "An arylcyclohexylamine drug and analogue of ketamine, though slightly less potent. Produces similar dissociative and anaesthetic effects. Very rare.", - "aliases": [ - "2-meo-ketamine" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "dose": "Insufflated Threshold: 5-15mg Light: 15-60mg Common: 60-130mg Strong: 130-200mg+", - "onset": "10-20 minutes", - "duration": "1-2 hours", - "after-effects": "2-4 hours" - }, - "pretty_name": "Methoxyketamine", - "aliases": [ - "2-meo-ketamine" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Insufflated": { - "Threshold": "5-15mg", - "Light": "15-60mg", - "Common": "60-130mg", - "Strong": "130-200mg+" - } - }, - "formatted_duration": { - "value": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-20", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methoxyketamine.shtml" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 238 - }, - "4f-neb": { - "name": "4f-neb", - "properties": { - "summary": "The 4-Fluoro analogue of N-Ethylbuphedrone (NEB) is a part of the cathinone class.", - "dose": "Oral Light: 75-100mg Common: 100-150mg Strong: 150-300mg | Insufflated Light: 50-75 Common: 75-150mg Strong: 150-250mg.", - "onset": "Oral: 15-30 minutes. | Insufflated: 5-10 minutes.", - "duration": "Oral: 90-180 minutes. | Insufflated: 50-100 minutes.", - "after-effects": "1-12 hours." - }, - "pretty_name": "4F-NEB", - "formatted_dose": { - "Oral": { - "Light": "75-100mg", - "Common": "100-150mg", - "Strong": "150-300mg" - }, - "Insufflated": { - "Light": "50-75", - "Common": "75-150mg", - "Strong": "150-250mg." - } - }, - "formatted_duration": { - "Oral": "90-180", - "Insufflated": "50-100", - "_unit": "minutes" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 239 - }, - "brotizolam": { - "name": "brotizolam", - "properties": { - "summary": "Benzodiazepine analogue which is sedating, hypnotic and anxiolytic. It is available as prescription medicine in much of Europe, and is an extremely potent drug active at only 80ug. May cause amnesia and lowered inhibitions in overdose. Danger of respiratory depression when combined with other depressants. Short half life.", - "dose": "Oral Threshold: 80ug Light: 100ug-200ug Common: 200-400ug Strong: 400ug-600ug+", - "avoid": "All other CNS depressants.", - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming", - "depressant" - ], - "onset": "Oral: 10-30 minutes. Insufflated: 2-10 minutes.", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia.", - "duration": "Oral: 4-8 hours. Insufflated: 2-6 hours.", - "bioavailabity": "Oral 70% +/- 24%.", - "after-effects": "1-4 hours.", - "dose_to_diazepam": "Brotizolam - 0.25mg ~=10mg Diazepam.", - "aliases": [ - "lendormin" - ] - }, - "pretty_name": "Brotizolam", - "aliases": [ - "lendormin" - ], - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Threshold": "80ug", - "Light": "100ug-200ug", - "Common": "200-400ug", - "Strong": "400ug-600ug+" - } - }, - "formatted_duration": { - "Oral": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "" - ], - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Pharmacokinetics of brotizolam in healthy subjects following intravenous and oral administration. http://www.ncbi.nlm.nih.gov/pubmed/6661374" - ] - }, - "id": 240 - }, - "zolpidem": { - "name": "zolpidem", - "properties": { - "summary": "Commonly prescribed for insomnia, Ambien (zolpidem) can cause realistic hallucinations similar to those of deliriants, and is very likely to cause amnesia at higher doses. Take care when using this drug, as it tends to lower inhibitions to a level which causes the user to do things they might not normally do when sober.", - "aliases": [ - "ambien", - "stilnox" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "dose": "Light: 2.5-5mg Common: 5-10mg Strong: 10-20mg Heavy: 20-30mg+", - "onset": "15-45 minutes.", - "effects": "Helps with insomnia/sleep, hallucinations through all physical senses, increased or decreased libido, delusions", - "avoid": "All other CNS depressants", - "duration": "5-10 hours.", - "after-effects": "1-24 hours.", - "bioavailability": "Oral: 70%" - }, - "pretty_name": "Zolpidem", - "aliases": [ - "ambien", - "stilnox" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg", - "Heavy": "20-30mg+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Helps with insomnia/sleep", - "hallucinations through all physical senses", - "increased or decreased libido", - "delusions" - ], - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Appetite enhancement": "https://psychonautwiki.org/wiki/Appetite_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Irreversible ischemic hand following intraarterial injection of zolpidem powder - http://www.ncbi.nlm.nih.gov/pubmed/14705853", - "Clinical pharmacokinetics and pharmacodynamics of zolpidem. Therapeutic implications - http://www.ncbi.nlm.nih.gov/pubmed/8521677" - ] - }, - "id": 241 - }, - "dalt": { - "name": "dalt", - "properties": { - "summary": "Psychedelic drug of the tryptamine class.", - "aliases": [ - "n,n-diallyltryptamine", - "diallyltryptamine" - ], - "duration": "3-6 hours.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "onset": "15-45 minutes.", - "after-effects": "1-4 hours." - }, - "pretty_name": "DALT", - "aliases": [ - "n,n-diallyltryptamine", - "diallyltryptamine" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "none": { - "Light": "20-40mg", - "Common": "40-60mg", - "Strong": "60mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 242 - }, - "bromazolam": { - "name": "bromazolam", - "properties": { - "summary": "A rather novel Benzodiazepine that is structurally quite close to Alprazolam.", - "duration": "5-8 hours.", - "onset": "15-45 minutes.", - "after-effects": "1-12 hours.", - "categories": [ - "benzodiazepine", - "research-chemical", - "tentative", - "habit-forming" - ], - "avoid": "All other CNS depressants.", - "dose": "Oral Light: 0.5-1mg Common: 1-2mg Strong: 2-4mg+", - "aliases": [ - "xli-268", - "xli268" - ] - }, - "pretty_name": "Bromazolam", - "aliases": [ - "xli-268", - "xli268" - ], - "categories": [ - "benzodiazepine", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 243 - }, - "chloral-betaine": { - "name": "chloral-betaine", - "properties": { - "summary": "Sedative-hypnotic drug that was introduced into the United States in the 60's. Betaine complex with Chloral hydrate, thus makes it act as an extended version of Chloral hydrate then to Trichloroethanol, which is responsible for most of its effects.", - "onset": "15-30 minutes.", - "duration": "3-7 hours.", - "dose": "Oral Light: 125-250mg Common: 250-500mg. Strong: 500-1000mg.", - "categories": [ - "depressant", - "habit-forming" - ], - "after-effects": "2-8 hours." - }, - "pretty_name": "Chloral betaine", - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "125-250mg", - "Common": "250-500mg.", - "Strong": "500-1000mg." - } - }, - "formatted_duration": { - "value": "3-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-8", - "_unit": "hours" - }, - "id": 244 - }, - "tuinal": { - "name": "tuinal", - "properties": { - "summary": "Brand name of a combination drug of two barbiturate salts (Secobarbital/Amobarbital) in equal amounts. It was introduced in the late 1940's.", - "dose": "Oral Light: 25-75mg Common: 75-150mg. Strong: 150-300mg.", - "onset": "10-45 minutes.", - "duration": "5-12 hours.", - "avoid": "All other CNS depressants.", - "aliases": [ - "tuinol", - "chirstmas-trees", - "rainbows", - "beans", - "nawls", - "jeebs" - ], - "categories": [ - "barbiturate", - "depressant", - "habit-forming" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Tuinal", - "aliases": [ - "tuinol", - "chirstmas-trees", - "rainbows", - "beans", - "nawls", - "jeebs" - ], - "categories": [ - "barbiturate", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "25-75mg", - "Common": "75-150mg.", - "Strong": "150-300mg." - } - }, - "formatted_duration": { - "value": "5-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 245 - }, - "noctec": { - "name": "noctec", - "properties": { - "summary": "Chloral Hydrate, a sedative drug discovered in 1832 with a history of recreational use going back to the 19th century. Sometimes prescribed for extreme insomnia. For such an old drug, relatively little is known about its long-term term effects on the body. Produces intoxication comparable to alcohol or benzodiazepines.", - "aliases": [ - "chloral-hydrate", - "aquachloral", - "somnos" - ], - "onset": "20-60 minutes.", - "duration": "5-10 hours", - "avod": "All other CNS depressants.", - "dose": "Light: 200mg's Common: 200-500mg's Strong: 500-1000mg's.", - "categories": [ - "depressant", - "habit-forming" - ], - "after-effects": "2-6 hours." - }, - "pretty_name": "Chloral hydrate", - "aliases": [ - "chloral-hydrate", - "aquachloral", - "somnos" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "200mg", - "Common": "200-500mg", - "Strong": "500-1000mg" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "id": 246 - }, - "5-meo-eipt": { - "name": "5-meo-eipt", - "properties": { - "summary": "A little known and little studied tryptamine and analogue of EiPT, also related to DiPT and DET. Probably a psychedelic. Few reports of effects.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "onset": "Oral: 15-45 minutes. | Insufflated: 1-10 minutes.", - "dose": "Oral Threshold: 2-5mg Light: 5-10mg Common: 10-20mg Strong: 20-25mg+ | Insufflated Threshold: 1-3mg Light: 3-7mg Common: 7-15mg Strong: 15-20mg+", - "duration": "Oral: 5-10 hours. | Insufflated: 3-6 hours.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "5meoeipt" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "5-MeO-EiPT", - "aliases": [ - "5meoeipt" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "2-5mg", - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-25mg+" - }, - "Insufflated": { - "Threshold": "1-3mg", - "Light": "3-7mg", - "Common": "7-15mg", - "Strong": "15-20mg+" - } - }, - "formatted_duration": { - "Oral": "5-10", - "Insufflated": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Insufflated": "1-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 247 - }, - "ethylone": { - "name": "ethylone", - "properties": { - "summary": "A euphoric stimulant often sold in place of MDMA since methylone was banned. Slightly less potent and empathogenic than methylone, it is often described as more of a 'straight stimulant.'", - "aliases": [ - "bk-mdea" - ], - "onset": "30-45 minutes.", - "duration": "2-4 hours.", - "after-effects": "6-24 hours.", - "dose": "Oral Light: 125-175mg Common: 200-250mg Strong: 250-400mg", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen" - ] - }, - "pretty_name": "Ethylone", - "aliases": [ - "bk-mdea" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "125-175mg", - "Common": "200-250mg", - "Strong": "250-400mg" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_bkMDEA.shtml" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "id": 248 - }, - "pentedrone": { - "name": "pentedrone", - "properties": { - "onset": "Oral: 15-30 minutes. | Insufflated: 5-10 minutes.", - "summary": "A potent NDRI cathinone-type stimulant with more-ish effects but not thought to be especially enjoyable.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "dose": "Oral Light: 5-10mg Common: 10-15mg Strong: 15-25mg | Insufflated Light: 2-5mg Common: 5-10mg Strong: 10-20mg | Rectal Light: 2-5mg Common: 5-10mg strong: 10-20mg.", - "duration": "Oral: 2-6 hours. | Insufflated: 1-4 hours.", - "after-effects": "1-12 hours.", - "avoid": "All other stimulants." - }, - "pretty_name": "Pentedrone", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-25mg" - }, - "Insufflated": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10-20mg" - }, - "Rectal": { - "Light": "2-5mg", - "Common": "5-10mg", - "strong": "10-20mg." - } - }, - "formatted_duration": { - "Oral": "2-6", - "Insufflated": "1-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Pentedrone.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 249 - }, - "2-mec": { - "name": "2-mec", - "properties": { - "summary": "Cathinone which some users report to feel like a weaker MDMA with a shorter onset.", - "dose": "Oral Light: 50-100mg Common: 100-200mg Strong: 200-350mg+ | Insufflated Light: 25-50mg Common: 50-100mg Strong: 100-250mg+", - "duration": "Oral: 3-5 hours. | Insufflated: 2-4 hours.", - "after-effects": "1-6 hours.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ] - }, - "pretty_name": "2-MEC", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-200mg", - "Strong": "200-350mg+" - }, - "Insufflated": { - "Light": "25-50mg", - "Common": "50-100mg", - "Strong": "100-250mg+" - } - }, - "formatted_duration": { - "Oral": "3-5", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 250 - }, - "opium": { - "name": "opium", - "properties": { - "summary": "Opium is a naturally occurring analgesic harvested as a latex from ripe Papaver somniferum (opium poppy) pods. The sap of the poppy plant primarily contains codeine and morphine with the amounts varying by plant, which can be made into a tea and consumed raw, or further processed.", - "aliases": [ - "O" - ], - "avoid": "Easy to overdose. Don't smoke from aluminum foil.", - "marquis": "Dark grayish reddish Brown", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Opium", - "aliases": [ - "O" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral_Tea": { - "Common": "333-500mg.", - "Fatal": "2000mg" - }, - "Smoked": { - "Common": "100mg" - } - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Opium.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 251 - }, - "morpheridine": { - "name": "morpheridine", - "properties": { - "summary": "Is a 4-Phenylpiperidine derivative that is related to Pehidine. It is roughly 4x as potent as the parent compound, does not cause convulsions such as Pethidine.", - "dose": "Oral Light: 5-10mg. Common: 10-20mg Strong: 20-35mg's.", - "onset": "Oral 15-35 minutes.", - "duration": "Oral 4-6 hours.", - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ], - "warning": "Do not mix with any other CNS depressants.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Morpheridine", - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg.", - "Common": "10-20mg", - "Strong": "20-35mg" - } - }, - "formatted_duration": { - "value": "Oral", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Oral", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 252 - }, - "2-fma": { - "name": "2-fma", - "properties": { - "summary": "A long-acting stimulant often compared to lisdexamphetamine. Thought to lack some of amphetamine's neurotoxic metabolites. Very functional, and for this reason it is commonly used for studying.", - "dose": "Oral Light: 15-25mg Common: 25-35mg Strong: 35-65mg Heavy: 65-80mg+ | NOTE: Sensitivity varies from| person-to-person and with usage factors. Higher doses can often result in long crashes and sleepless nights. Always start low and titrate slowly.", - "aliases": [ - "2fma" - ], - "marquis": "Light yellow", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "onset": "20-60 minutes", - "duration": "6-8 hours", - "after-effects": "1-24 hours." - }, - "pretty_name": "2-FMA", - "aliases": [ - "2fma" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "15-25mg", - "Common": "25-35mg", - "Strong": "35-65mg", - "Heavy": "65-80mg+" - }, - "person-to-person": {} - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Sensitivity varies from", - "id": 253 - }, - "3-mmc": { - "name": "3-mmc", - "properties": { - "onset": "Within an hour.", - "duration": "4-7 hours (dependent on dose/ROA/lots of stuff)", - "summary": "A euphoric stimulant similar to mephedrone but said to lack much of the \"magic.\" Never gained the same popularity. Slightly less potent.", - "after-effects": "3-4 hours.", - "dose": "Light: 25-75mg Common: 75-150mg Strong: 150mg-300mg+", - "categories": [ - "stimulant", - "habit-forming", - "empathogen" - ], - "aliases": [ - "3mmc", - "3-methylmethcathinone", - "3methylmethcathinone", - "3-meph", - "3-mephedrone" - ], - "effects": "increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "3-MMC", - "aliases": [ - "3mmc", - "3-methylmethcathinone", - "3methylmethcathinone", - "3-meph", - "3-mephedrone" - ], - "categories": [ - "stimulant", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "25-75mg", - "Common": "75-150mg", - "Strong": "150mg-300mg+" - } - }, - "formatted_duration": { - "value": "4-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Within" - }, - "formatted_effects": [ - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "3-4", - "_unit": "hours" - }, - "id": 254 - }, - "cocaine": { - "name": "cocaine", - "properties": { - "detection": "Saliva: 1 day, Urine: 4-5 days, Hair: up to 90 days", - "dose": "Insufflated Light: 20-50mg Common: 50-100mg Strong: 100-150mg Heavy: 150mg+ | NOTE: Depending on purity, dosage will vary", - "summary": "A highly popular, short acting CNS stimulant that works by blocking the reuptake of dopamine, serotonin, and norepinephrine. It is known to increase euphoria, confidence, sex-drive, focus, body temperature, and heart rate. Cocaine can cause severe vasoconstriction and is known to be cardiotoxic and have a high potential for compulsive redosing and addiction.", - "duration": "1-1.5 hours", - "marquis": "Clear (No change)", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "effects": "Elevated mood. Increase in irritability, hyper-inflated ego, euphoria, stimulation, raised heartrate, numbing effects depending on ROA, nausea (particularly at high doses)", - "aliases": [ - "coke" - ], - "onset": "Rapid.", - "bioavailability": "Cocaine Oral 25-35% | Insufflated 40-60%. NOTE: This is for Cocaine HCl.", - "after-effects": "1-4 hours." - }, - "pretty_name": "Cocaine", - "aliases": [ - "coke" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Insufflated": { - "Light": "20-50mg", - "Common": "50-100mg", - "Strong": "100-150mg", - "Heavy": "150mg+" - } - }, - "formatted_duration": { - "value": "1-1.5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Rapid." - }, - "formatted_effects": [ - "Elevated mood", - "Increase in irritability", - "hyper-inflated ego", - "euphoria", - "stimulation", - "raised heartrate", - "numbing effects depending on ROA", - "nausea (particularly at high doses)" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Cocaine.shtml" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Bronchodilation": "https://psychonautwiki.org/wiki/Bronchodilation", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Ego inflation": "https://psychonautwiki.org/wiki/Ego_inflation", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temporary erectile dysfunction": "https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought organization": "https://psychonautwiki.org/wiki/Thought_organization", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "dose_note": " NOTE: Depending on purity, dosage will vary", - "sources": { - "_general": [ - "Rhabdomyolysis associated with cocaine abuse. -https://www.ncbi.nlm.nih.gov/pubmed/1743698", - "Rhabdomyolysis associated with cocaine abuse. - https://www.ncbi.nlm.nih.gov/pubmed/1743698", - "The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, a... - https://www.ncbi.nlm.nih.gov/pubmed/18342307", - "Effects of concurrent use of alcohol and cocaine. - http://www.ncbi.nlm.nih.gov/pubmed/12133112", - "Cocaine-like neurochemical effects of antihistaminic medications. - http://www.ncbi.nlm.nih.gov/pubmed/18363822", - "Cocaine cardiotoxicity: a review of the pathophysiology, pathology, and treatment options. - http://www.ncbi.nlm.nih.gov/pubmed/19463023", - "Citalopram enhances cocaine's subjective effects in rats. - http://www.ncbi.nlm.nih.gov/pubmed/20195220", - "Role of voltage-gated sodium, potassium and calcium channels in the development of cocaine-associated cardiac arrhythmias. - http://www.ncbi.nlm.nih.gov/pubmed/20573078", - "High cocaine dosage decreases neurogenesis in the hippocampus and impairs working memory. - http://www.ncbi.nlm.nih.gov/pubmed/20731634", - "The effects of combinations of intranasal cocaine, smoked marijuana, and task performance on heart rate and blood pressure. - http://www.ncbi.nlm.nih.gov/pubmed/2162543", - "Lack of cocaine-like discriminative-stimulus effects of σ-receptor agonists in rats. - http://www.ncbi.nlm.nih.gov/pubmed/21808192", - "Pregabalin reduces cocaine self-administration and relapse to cocaine seeking in the rat. - http://www.ncbi.nlm.nih.gov/pubmed/22734646", - "Cocaine potentiates MDMA-induced oxidative stress but not dopaminergic neurotoxicity in mice: implications for the pathogenesis of free radical-ind... - http://www.ncbi.nlm.nih.gov/pubmed/23681166", - "Effects of escitalopram on attentional bias to cocaine-related stimuli and inhibitory control in cocaine-dependent subjects. - http://www.ncbi.nlm.nih.gov/pubmed/23761390", - "Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. - http://www.ncbi.nlm.nih.gov/pubmed/24296074", - "Long Withdrawal of Methylphenidate Induces a Differential Response of the Dopaminergic System and Increases Sensitivity to Cocaine in the Prefronta... - http://www.ncbi.nlm.nih.gov/pubmed/26509840", - "Cocaine tolerance and cross-tolerance. - http://www.ncbi.nlm.nih.gov/pubmed/8093724", - "Cocaethylene is as cardiotoxic as cocaine but is less toxic than cocaine plus ethanol. - http://www.ncbi.nlm.nih.gov/pubmed/8761012", - "Differential potentiation of L-tryptophan-induced head-twitch response in mice by cocaine and sertraline. - http://www.ncbi.nlm.nih.gov/pubmed/8831798", - "Cocaine contamination of United States paper currency. - http://www.ncbi.nlm.nih.gov/pubmed/8835657", - "A study suggests that having a history of cocaine and poly drug abuse can lead to acute open-angle glaucoma - http://journals.lww.com/glaucomajournal/Abstract/2011/09000/Substance_Use_Disorder_and_the_Risk_of_Open_angle.9.aspx", - "using cocaine while pregnant is dangerous for the fetus's health - https://www.drugabuse.gov/publications/research-reports/cocaine/what-are-effects-maternal-cocaine-use" - ] - }, - "combos": { - "mushrooms": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "lsd": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "dmt": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "mescaline": { - "status": "Caution", - "note": "The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops" - }, - "dox": { - "status": "Unsafe", - "note": "The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of cocaine can easily lead to thought loops. Coming down from cocaine while the DOx is still active can be quite anxiogenic" - }, - "nbomes": { - "status": "Unsafe", - "note": "Cocaine and NBOMes both provide considerable stimulation. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure." - }, - "2c-x": { - "status": "Caution", - "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics. Combination of the stimulating effects may be uncomfortable." - }, - "2c-t-x": { - "status": "Unsafe", - "note": "Cocaine and 2c-t-x both provide considerable stimulation. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure." - }, - "amt": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Unsafe", - "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics. " - }, - "cannabis": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "ketamine": { - "status": "Caution", - "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury." - }, - "mxe": { - "status": "Caution", - "note": "Stimulants taken with MXE can lead to hypermanic states much more easily, especially if sleep is avoided." - }, - "dxm": { - "status": "Unsafe", - "note": "Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues" - }, - "pcp": { - "status": "Unsafe", - "note": "This combination can easily lead to hypermanic states" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "This combination of stimulants will increase strain on the heart. It is not generally worth it as cocaine has a mild blocking effect on dopamine releasers like amphetamine" - }, - "mdma": { - "status": "Caution", - "note": "Cocaine blocks some of the desirable effects of MDMA while increasing the risk of heart attack." - }, - "caffeine": { - "status": "Caution", - "note": "Both stimulants, risk of tachycardia, hypertension, and in extreme cases heart failure." - }, - "alcohol": { - "status": "Unsafe", - "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol less. Cocaine is potentiated somewhat by alcohol because of the formation of cocaethylene." - }, - "ghb/gbl": { - "status": "Caution", - "note": "Stimulants increase respiration rate allowing a higher dose of sedatives. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest. Likewise the G can wear off and leave a dangerous concentration of cocaine behind" - }, - "opioids": { - "status": "Dangerous", - "note": "Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest." - }, - "tramadol": { - "status": "Dangerous", - "note": "Tramadol and stimulants both increase the risk of seizures." - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Dangerous", - "note": "This combination is poorly explored" - }, - "ssris": { - "status": "Low Risk & No Synergy", - "note": "May reduce each others' effectiveness. Cocaine can reduce mental stability and therefore exacerbate conditions which SSRIs are used to treat." - } - }, - "id": 255 - }, - "ethylphenidate": { - "name": "ethylphenidate", - "properties": { - "dose": "Oral Light: 20-40mg Common: 40-100mg Strong: 100-150mg Heavy: 150-200mg | Plugged/Rectal Light: 5-15mg Common: 15-30mg Strong: 30-50mg Heavy: 50-75mg | NOTE: Ethylphenidate should NOT be insufflated (see summary for more details). This drug reacts with users in varying ways, so start low and work your way up.", - "effects": "Focus/mental clarity, Abstract thinking, Euphoria, Stimulation, Increased music appreciation, Warm fuzzy body high, Increased desire to talk, Wakefulness, increased sex drive, Chest pain, Vasoconstriction, Jaw Tension, Restlessness, high blood pressure, compulsion to redose, paranoia", - "duration": "Oral: 4-10 hours. | Insufflated: 2-6 hours. | Plugged: 2-6 hours.", - "onset": "Insufflated: 1-10 minutes | Plugged: 5-20 minutes | Oral: 45-120 minutes", - "summary": "Potent psychostimulant, similar to Methylphenidate. \u0002Note: Ethylphenidate should \u0016NOT\u0016 be insufflated as it is known to be highly caustic and will cause serious harm to your nasal septum, even with light usage.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "common" - ], - "aliases": [ - "eph" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Ethylphenidate", - "aliases": [ - "eph" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "20-40mg", - "Common": "40-100mg", - "Strong": "100-150mg", - "Heavy": "150-200mg" - }, - "Plugged/Rectal": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg", - "Heavy": "50-75mg" - } - }, - "formatted_duration": { - "Oral": "4-10", - "Insufflated": "2-6", - "Plugged": "2-6", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "1-10", - "Plugged": "5-20", - "Oral": "45-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Focus/mental clarity", - "Abstract thinking", - "Euphoria", - "Stimulation", - "Increased music appreciation", - "Warm fuzzy body high", - "Increased desire to talk", - "Wakefulness", - "increased sex drive", - "Chest pain", - "Vasoconstriction", - "Jaw Tension", - "Restlessness", - "high blood pressure", - "compulsion to redose", - "paranoia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ethylphenidate.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Ethylphenidate should NOT be insufflated (see summary for more details). This drug reacts with users in varying ways, so start low and work your way up.", - "sources": { - "_general": [ - "https://www.ncbi.nlm.nih.gov/pubmed/10820132", - "Ethylphenidate formation in human subjects after the administration of a single dose of methylphenidate and ethanol - https://www.ncbi.nlm.nih.gov/pubmed/10820132", - "Methylphenidate and its ethanol transesterification metabolite ethylphenidate: brain disposition, monoamine transporters and motor activity - http://www.ncbi.nlm.nih.gov/pubmed/17218796" - ] - }, - "id": 256 - }, - "clotiazepam": { - "name": "clotiazepam", - "properties": { - "summary": "Is a thienodiazepine substance. It differs from most other benzodiazepines in which the benzene ring has been replaced by a thiophene ring.", - "dose": "Oral Light: 2.5-5mg Common: 5-10mg Strong: 10-15mg+", - "onset": "10-30 minutes.", - "duration": "4-8 hours.", - "after-effects": "4-8 hours.", - "categories": [ - "benzodiazepine", - "habit-forming", - "tentative", - "depressant" - ], - "aliases": [ - "clozan", - "distensan", - "trecalmo", - "rize", - "rizen", - "veratran" - ] - }, - "pretty_name": "Clotiazepam", - "aliases": [ - "clozan", - "distensan", - "trecalmo", - "rize", - "rizen", - "veratran" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-15mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "4-8", - "_unit": "hours" - }, - "id": 257 - }, - "homomazindol": { - "name": "homomazindol", - "properties": { - "summary": "A potent analogue of mazindol, a rare, atypical stimulant drug and appetite suppressant occasionally prescribed in cases of severe obesity.", - "categories": [ - "stimulant", - "tentative", - "research-chemical", - "habit-forming" - ] - }, - "pretty_name": "Homomazindol", - "categories": [ - "stimulant", - "tentative", - "research-chemical", - "habit-forming" - ], - "id": 258 - }, - "triazolam": { - "name": "triazolam", - "properties": { - "summary": "An uncommon and very short acting benzodiazepine. Sedating and hypnotic, and may induce amnesia and lowered inhibitions at high doses.", - "dose": "Light: 0.125-0.25mg Common: 0.25-0.5mg Strong: 0.5-1.5mg+", - "onset": "10-20 minutes.", - "duration": "Oral: 4-7 hours. | Insufflated: 3-5 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, but primarily sedative or hypnotic.", - "after-effects": "1-6 hours.", - "alias": "Halcion", - "dose_to_diazepam": "Triazolam - 0.5mg ~=10mg Diazepam.", - "aliases": [ - "halcion" - ] - }, - "pretty_name": "Triazolam", - "aliases": [ - "halcion" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.125-0.25mg", - "Common": "0.25-0.5mg", - "Strong": "0.5-1.5mg+" - } - }, - "formatted_duration": { - "Oral": "4-7", - "Insufflated": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-20", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "but primarily sedative or hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 259 - }, - "mephenmetrazine": { - "name": "mephenmetrazine", - "properties": { - "dose": "Oral Light: 5-15mg Common: 15-25mg Strong: 25-40mg. | Insufflated Light: 5-10mg Common: 10-20mg Strong: 20-25mg's.", - "duration": "Oral: 3-5 hours. | Insufflated 2-3 hours.", - "avoid": "Other stimulants.", - "summary": "4-Methylphenmetrazine is an empathogen of the phenylmorpholine class that seems to have a very rapid tolerance build up.", - "onset": "Oral: 15-30 minutes. | Insufflated: 5-10 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming", - "empathogen" - ], - "aliases": [ - "4-mpm", - "4-methylphenmetrazine" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "4-MPM", - "aliases": [ - "4-mpm", - "4-methylphenmetrazine" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-25mg", - "Strong": "25-40mg." - }, - "Insufflated": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-25mg" - } - }, - "formatted_duration": { - "Oral": "3-5", - "Insufflated": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 260 - }, - "nm-2-ai": { - "name": "nm-2-ai", - "properties": { - "summary": "Stimulant that is in the aminoindane class. Is it quite close to it's bigger brother 2-AI. Yet this has a lower potency, has a longer duration though.", - "onset": "15-45 minutes.", - "duration": "3-5 hours.", - "categories": [ - "stimulant", - "empathogen" - ], - "note": "Most of the reports are in pellets that have more than one drug in them (Namely MPA). So start slow and work your way up.", - "dose": "Oral Light: 50-100mg Common: 100-150 Strong: 150mg-200mg+", - "after-effects": "1-8 hours." - }, - "pretty_name": "NM-2-AI", - "categories": [ - "stimulant", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-150", - "Strong": "150mg-200mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 261 - }, - "4-cic": { - "name": "4-cic", - "properties": { - "summary": "Inactive.", - "categories": [ - "inactive" - ] - }, - "pretty_name": "4-CIC", - "categories": [ - "inactive" - ], - "id": 262 - }, - "baclofen": { - "name": "baclofen", - "properties": { - "dose": "Oral Light: 10-20mg Common: 20-50 Strong: 50-75 Heavy: 75-125mg | NOTE: Past 125mg's you may run into the issue of blacking out.", - "duration": "3-6 hours.", - "onset": "15-45 minutes.", - "avoid": "All other CNS depressants.", - "summary": "Also known as Lioresal, Baclofen is a GABAb receptor agonist and central nervous system depressant used to treat spasticity, and holds promise as a treatment for alcoholism. It exhibits mild intoxicating effects similar to phenibut or pregabalin.", - "aliases": [ - "gablofen" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "bioavailability": "Oral: 74%.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Baclofen", - "aliases": [ - "gablofen" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-50", - "Strong": "50-75", - "Heavy": "75-125mg" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "dose_note": " NOTE: Past 125mg's you may run into the issue of blacking out.", - "sources": { - "_general": [ - "A pilot study assessing pharmacokinectics and tolerability of Oral and intravenous Baclofen in healthy adult volunteers. http://www.ncbi.nlm.nih.gov/pubmed/25028414" - ] - }, - "id": 263 - }, - "demerol": { - "name": "demerol", - "properties": { - "summary": "A phenylpiperidine opioid first synthesised by Otto Eisleb in 1939, better known by the names meperidine and pethidine. An analgesic, once widely prescribed it has since declined in usage due to the discovery of a toxic metabolite - norpethidine. Also reacts dangerously with many drugs.", - "onset": "30-60 minutes", - "duration": "4-6 hours.", - "aliases": [ - "pethidine", - "meperidine" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "dose": "Light: 50-100mg Common: 100-200mg Strong: 200-400mg+", - "after-effects": "2-10 hours.", - "avoid": "All other CNS depressants.", - "bioavailability": "Oral 50-60% | Rectal 55% | Intramuscular 80-85%" - }, - "pretty_name": "Pethidine", - "aliases": [ - "pethidine", - "meperidine" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-200mg", - "Strong": "200-400mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "2-10", - "_unit": "hours" - }, - "id": 264 - }, - "3-cmc": { - "name": "3-cmc", - "properties": { - "duration": "Oral: 2-4 hours. | Insufflated: 1-2 hours.", - "onset": "Oral: 30-90 minutes. | Insufflated: 10-30 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "summary": "A rarely seen halogenated cathinone drug. Likely to be a stimulant, possibly an entactogen. (Note: The amphetamine analogue of this drug, 4-CA, is a highly dangerous neurotoxin, no data about the safety of this one, but should likely be avoided)", - "dose": "Oral Light: 30-60mg Common: 60-100mg Strong: 100-180mg. | Insufflated Light: 20-40mg Common: 40-80mg Strong: 80-100mg.", - "after-effects": "Oral: 4-12 hours. | Insufflated: 3-6 hours.", - "aliases": [ - "3cmc" - ] - }, - "pretty_name": "3-CMC", - "aliases": [ - "3cmc" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "30-60mg", - "Common": "60-100mg", - "Strong": "100-180mg." - }, - "Insufflated": { - "Light": "20-40mg", - "Common": "40-80mg", - "Strong": "80-100mg." - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-90", - "Insufflated": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "Oral": "4-12", - "Insufflated": "3-6", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 265 - }, - "acetylfentanyl": { - "name": "acetylfentanyl", - "properties": { - "summary": "Acetyl-Fentanyl is an opioid analgesic substance that is an analogue of Fentanyl. It's potency is roughly ~6.67 times that of Morphine. Making it ~15 times less potent than its parent compound Fentanyl.", - "duration": "1-4 hours.", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "aliases": [ - "acetyl-fentanyl", - "a-f" - ], - "dose": "Oral Light: 2-4mg Common: 4-6mg Strong: 6-10mg+ Insufflated Light: 1-3mg Common: 3-5mg Strong: 5-7mg+ NOTE: ~3.75mg Freebase = ~125ug Fentanyl IV = ~10mg Morphine IV'd.", - "onset": "5-20 minutes.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-8 hours." - }, - "pretty_name": "Acetylfentanyl", - "aliases": [ - "acetyl-fentanyl", - "a-f" - ], - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "1-3mg", - "Common": "3-5mg", - "Strong": "5-7mg+" - } - }, - "formatted_duration": { - "value": "1-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-20", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Acetylfentanyl.shtml" - }, - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " NOTE: ~3.75mg Freebase = ~125ug Fentanyl IV = ~10mg Morphine IV'd.", - "sources": { - "_general": [ - "Acetylfentanyl in extreme toxicity has caused Cerebral hemorrhage - http://www.tandfonline.com/doi/abs/10.3109/15563650.2016.1139715" - ] - }, - "id": 266 - }, - "propofol": { - "name": "propofol", - "properties": { - "summary": "A very short acting sedative that is usually given at the start of general anesthesia, and for maintenance of the prior. It should never be used outside of a medical setting. With that in mind, if you do plan to use this drug recreational, please have a very experienced friend with you that has the skills to insert a cannula, and monitor you very closely.", - "duration": "Intravenous: 10-20 minutes.", - "onset": "Intravenous: 0-2 minutes.", - "experiences": "https://www.reddit.com/r/Drugs/comments/56n5vq/michael_jackson_the_addict/d8l0qe7 (PM Sleep/Hypnos if you'd like more information)", - "avoid": "If in a non-hospital setting, nearly all substances should be avoided. If you use this drug outside of a medical setting, have your partner or a friend monitor your pulse/breathing/etc. If your pulse drops below 50, or if you are taking less than 10 breaths per minute, call an ambulance. In some cases the user's body may be discoloured, in which case they are likely unconscious.", - "aliases": [ - "milk-of-amnesia", - "diprivan" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "after-effects": "Intravenous: 1-3 hours.", - "dose": "Intravenously Light: 10-30mg Common: 30-60mg Strong: 60-100mg | Note: Do not take this as gospel. Please read ~experiences if you use this substance outside of a hospital setting." - }, - "pretty_name": "Propofol", - "aliases": [ - "milk-of-amnesia", - "diprivan" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Intravenously": { - "Light": "10-30mg", - "Common": "30-60mg", - "Strong": "60-100mg" - } - }, - "formatted_duration": { - "Intravenous": "10-20", - "_unit": "minutes" - }, - "formatted_onset": { - "Intravenous": "0-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Intravenous": "1-3", - "_unit": "hours" - }, - "dose_note": " Note: Do not take this as gospel. Please read ~experiences if you use this substance outside of a hospital setting.", - "id": 267 - }, - "tma-2": { - "name": "tma-2", - "properties": { - "dose": "Threshold: 5-10mg Light: 10-20mg Common: 20-40mg Strong: 40-60mg+", - "onset": "20-120 minutes.", - "duration": "6-12 hours.", - "summary": "Trimethoxyamphetamine-2, a psychedelic amphetamine and stimulant first synthesised by Alexander Shulgin. An uncommon compound of similar activity to other psychedelic amphetamines. Short history of human use.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "TMA-2", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Light": "10-20mg", - "Common": "20-40mg", - "Strong": "40-60mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_TMA2.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal158.shtml" - }, - "formatted_aftereffects": { - "value": "Possibility", - "_unit": "hours" - }, - "id": 268 - }, - "4-meo-pcp": { - "name": "4-meo-pcp", - "properties": { - "summary": "An arylcyclohexamine dissociative anaesthetic related to PCP. First discovered in the 1960s by Parke-Davis, it was introduced to the RC market in 2008. Reported to be less potent than PCP. It is not commonly seen, but has seen some increase in popularity with the inavailability of other dissociatives.", - "aliases": [ - "4meopcp" - ], - "dose": "Oral Threshold: 25-50mg Light: 50-100mg Common: 100-150mg Strong: 150mg+ | NOTE: These doses are tentative and may need further research.", - "duration": "8-15 hours.", - "onset": "45-90 minutes.", - "after-effects": "1-24 hours.", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ] - }, - "pretty_name": "4-MeO-PCP", - "aliases": [ - "4meopcp" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "25-50mg", - "Light": "50-100mg", - "Common": "100-150mg", - "Strong": "150mg+" - } - }, - "formatted_duration": { - "value": "8-15", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4MeOPCP.shtml" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 269 - }, - "lorazepam": { - "name": "lorazepam", - "properties": { - "summary": "An intermediate acting benzodiazepine commonly known as Ativan, commonly prescribed as an alternative to Xanax. Sedating, hypnotic and anxiolytic. Potential to induce amnesia and lowered inhibitions in overdose. Do not combine with other depressants.", - "dose": "Oral Light: 0.5mg-1mg Common: 1-2mg Strong: 2-4mg's. | Intramuscular Light: 0.25-0.5mg Common: 0.5-1mg Strong: 1-2mg's.", - "onset": "5-30 minutes", - "duration": "4-8 hours", - "effects": "Anxiolytic, sedative, high muscle relaxant properties.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "aliases": [ - "ativan" - ], - "after-effects": "1-12 hours.", - "bioavailability": "Oral 85-90% | Insufflated 76-80%", - "dose_to_diazepam": "Lorazepam - 1mg ~=10mg Diazepam." - }, - "pretty_name": "Lorazepam", - "aliases": [ - "ativan" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5mg-1mg", - "Common": "1-2mg", - "Strong": "2-4mg" - }, - "Intramuscular": { - "Light": "0.25-0.5mg", - "Common": "0.5-1mg", - "Strong": "1-2mg" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "sedative", - "high muscle relaxant properties", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Nausea suppression": "https://psychonautwiki.org/wiki/Nausea_suppression", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Seizure suppression": "https://psychonautwiki.org/wiki/Seizure_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Warning - higher doses increase the chances of blacking out. Also 1mg Lorazepam ~= 10mg Diazepam.", - "sources": { - "_general": [ - "Role of dopaminergic and serotonergic systems on behavioral stimulatory effects of low-dose alprazolam and lorazepam. - https://www.ncbi.nlm.nih.gov/pubmed/11226811" - ] - }, - "id": 270 - }, - "marinol": { - "name": "marinol", - "properties": { - "duration": "Oral: 4-12 hours, depending on dose", - "summary": "Synthetically created Δ9-THC, the main psychoactive ingredient in cannabis.", - "half-life": "1.6–59 h,[3] 25–36 h (orally administered dronabinol)", - "categories": [ - "depressant", - "tentative" - ], - "aliases": [ - "dronabinol", - "syndros", - "cesamet", - "δ9-thc", - "δ9--tetrahydrocannabinol", - "delta9-tetrahydrocannabinol", - "delta9-thc" - ], - "onset": "Oral 30-90 minutes, with effects peaking at 2-3 hours", - "warning": "At higher doses, anxiety and panic attacks are common.", - "dose": "Light: 10-20mg Common: 20-30mg Strong: 30-50mg+", - "after-effects": "1-4 hours." - }, - "pretty_name": "Marinol", - "aliases": [ - "dronabinol", - "syndros", - "cesamet", - "δ9-thc", - "δ9--tetrahydrocannabinol", - "delta9-tetrahydrocannabinol", - "delta9-thc" - ], - "categories": [ - "depressant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-30mg", - "Strong": "30-50mg+" - } - }, - "formatted_duration": { - "Oral": "4-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Oral", - "_unit": "hours" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 271 - }, - "5-apdi": { - "name": "5-apdi", - "properties": { - "summary": "Also commonly known as IAP. A selective serotonin releasing agent with psychedelic and empathogenic properties. Users have often reported issues with the drug causing overheating and unwelcome bowel movements.", - "aliases": [ - "iap" - ], - "duration": "Oral: 8-14 hours.", - "onset": "Oral: 30-90 minutes.", - "dose": "Oral Light: 15-25mg Common: 25-50mg Strong: 50-75mg+", - "after-effects": "1-6 hours.", - "categories": [ - "empathogen", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "5-APDI", - "aliases": [ - "iap" - ], - "categories": [ - "empathogen", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "15-25mg", - "Common": "25-50mg", - "Strong": "50-75mg+" - } - }, - "formatted_duration": { - "Oral": "8-14", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_IAP.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 272 - }, - "ethyl-pentedrone": { - "name": "ethyl-pentedrone", - "properties": { - "summary": "A stimulant that came out around the same time as Ethyl-Hexedrone, not much information on it. Is in the cathinone family of substances. Related to Pentedrone.", - "aliases": [ - "nep", - "n-ethylpentedrone" - ], - "dose": "Insufflated Light: 10-20mg Common: 20-40 Strong: 40-60mg.", - "duration": "Oral: 3-6 hours. | Insufflated: 2-4 hours.", - "onset": "Oral: 10-20 minutes. | Insufflated: 5-10 minutes.", - "after-effects": "1-24 hours.", - "categories": [ - "stimulant", - "empathogen", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "ETHYL-PENTEDRONE", - "aliases": [ - "nep", - "n-ethylpentedrone" - ], - "categories": [ - "stimulant", - "empathogen", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Insufflated": { - "Light": "10-20mg", - "Common": "20-40", - "Strong": "40-60mg." - } - }, - "formatted_duration": { - "Oral": "3-6", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-20", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 273 - }, - "clonazepam": { - "name": "clonazepam", - "properties": { - "summary": "A medium-length common prescription benzodiazepine, often used to treat panic attacks because of its relatively fast sublingual onset. Primarily anxiolytic, but also possessing of other benzo traits.", - "onset": "20-45 minutes", - "duration": "8-12 hours.", - "avoid": "All other CNS depressants", - "aliases": [ - "klonopin", - "kpin" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "dose": "Oral Light: 0.25-0.5mg Common: 0.5-1mg Strong: 1-2mg+ | NOTE: 0.5mg of Clonazepam is approximately equal to 10mg Diazepam.", - "after-effects": "8-48 hours.", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "bioavailability": "Oral 90%", - "onset:": "20-45 minutes.", - "dose_to_diazepam": "Clonazepam - 0.5mg ~=10mg Diazepam." - }, - "pretty_name": "Clonazepam", - "aliases": [ - "klonopin", - "kpin" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "0.25-0.5mg", - "Common": "0.5-1mg", - "Strong": "1-2mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Seizure suppression": "https://psychonautwiki.org/wiki/Seizure_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "8-48", - "_unit": "hours" - }, - "dose_note": " NOTE: 0.5mg of Clonazepam is approximately equal to 10mg Diazepam.", - "sources": { - "_general": [ - "Mechanism of action of clonazepam in myoclonus in relation to effects on GABA and 5-HT. - https://www.ncbi.nlm.nih.gov/pubmed/2418652", - "Central effects in man of the novel schistosomicidal benzodiazepine meclonazepam. - https://www.ncbi.nlm.nih.gov/pubmed/4054198", - "Serum clonazepam concentrations in children with absence seizures. - http://www.ncbi.nlm.nih.gov/pubmed/1089913", - "Tapering clonazepam in patients with panic disorder after at least 3 years of treatment. - http://www.ncbi.nlm.nih.gov/pubmed/20473065" - ] - }, - "id": 274 - }, - "diazepam": { - "name": "diazepam", - "properties": { - "summary": "A very common and widely prescribed benzodiazepine with hypnotic and sedative qualities. The metre by which other benzodiazepines are compared. May cause amnesia and lowered inhibitions in excess. Has a relatively long half-life in comparison with other benzodiazepines.", - "dose": "Light: 2.5-5mg Common: 5-15mg Heavy: 15-30mg.", - "onset": "30-90 minutes.", - "duration": "10-24 hours.", - "after-effects": "1-120 hours.", - "avoid": "All other CNS depressants", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "aliases": [ - "valium" - ], - "effects": "Memory loss, Blackout potential, Motor skill impairment, Dizziness, Depression, Irritability, Aggression, Rage, Personality changes, Drowsiness, Appetite fluctuation, Euphoria, Relaxation, Anxiety suppression, Muscle relaxation, Emotional and social dissociation or de-realization (normally seen with long term use).", - "bioavailability": "Oral 85-100%", - "dose_to_diazepam": "Diazepam - 10mg ~=10mg Diazepam." - }, - "pretty_name": "Diazepam", - "aliases": [ - "valium" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-15mg", - "Heavy": "15-30mg." - } - }, - "formatted_duration": { - "value": "10-24", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Memory loss", - "Blackout potential", - "Motor skill impairment", - "Dizziness", - "Depression", - "Irritability", - "Aggression", - "Rage", - "Personality changes", - "Drowsiness", - "Appetite fluctuation", - "Euphoria", - "Relaxation", - "Anxiety suppression", - "Muscle relaxation", - "Emotional and social dissociation or de-realization (normally seen with long term use)", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Seizure suppression": "https://psychonautwiki.org/wiki/Seizure_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-120", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Alcohol and benzodiazepines in fatal poisonings. - https://www.ncbi.nlm.nih.gov/pubmed/12170103", - "NMDA receptor antagonists potently suppress the spontaneous withdrawal signs induced by discontinuation of long-term diazepam treatment in Fischer ... - http://www.ncbi.nlm.nih.gov/pubmed/9593834", - "Dual intoxication with diazepam and amphetamine: this drug interaction probably potentiates myocardial ischemia. - http://www.ncbi.nlm.nih.gov/pubmed/17320309", - "Effect of omeprazole and cimetidine on plasma diazepam levels. - http://www.ncbi.nlm.nih.gov/pubmed/2276389", - "Bioavailability of intranasal vs. rectal diazepam. - http://www.ncbi.nlm.nih.gov/pubmed/22981338", - "Dosing feasibility and tolerability of intranasal diazepam in adults with epilepsy. - http://www.ncbi.nlm.nih.gov/pubmed/25154625" - ] - }, - "id": 275 - }, - "phenetrazine": { - "name": "phenetrazine", - "properties": { - "dose": "Oral Threshold: 5-10mg Light: 10-25mg Common: 25-50mg Strong: 50-70mg. Heavy: 70mg+ | Insufflated Light: 10-20mg Common: 20-35mg Strong: 35-50mg Heavy: 50mg+", - "summary": "A rare phenethylamine stimulant related to 3-FPM. Virtually nothing is known about the pharmacology or effects of this compound but it is likely to have similar properties to other stimulants of its type. Not to be confused with phenmetrazine.", - "category": "tentative", - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ] - }, - "pretty_name": "Phenetrazine", - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-70mg.", - "Heavy": "70mg+" - }, - "Insufflated": { - "Light": "10-20mg", - "Common": "20-35mg", - "Strong": "35-50mg", - "Heavy": "50mg+" - } - }, - "id": 276 - }, - "loprazolam": { - "name": "loprazolam", - "properties": { - "summary": "Is an Imidazolobenzidazepine derivative that has all the classic benzodiazepine effects. Is usually only prescribed for a short amount of time for insomnia.", - "dose": "Light: 0.25-0.5mg Common: 0.5-1.5mg Strong: 1.5-3mg+", - "onset": "30-50 minutes.", - "duration": "6-10 hours.", - "after-effects": "1-8 hours.", - "categories": [ - "depressant", - "habit-forming" - ], - "dose_to_diazepam": "Lopazolam - 1-2mg's ~=10mg Diazepam.", - "aliases": [ - "dormonoct" - ] - }, - "pretty_name": "Loprazolam", - "aliases": [ - "dormonoct" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "0.25-0.5mg", - "Common": "0.5-1.5mg", - "Strong": "1.5-3mg+" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-50", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 277 - }, - "moclobemide": { - "name": "moclobemide", - "properties": { - "summary": "A reversible MAOI which is prescribed to treat depression and anxiety. Its reversibility and short-acting length of effects often means it is used in \"pharmahuasca\" preparations.", - "duration": "2-6 hours.", - "dose": "Light: 150mg Common: 300mg Strong: 600mg.", - "onset": "30-90 minutes." - }, - "pretty_name": "Moclobemide", - "formatted_dose": { - "Oral": { - "Light": "150mg", - "Common": "300mg", - "Strong": "600mg." - } - }, - "formatted_duration": { - "value": "2-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Moclobemide.shtml" - }, - "id": 278 - }, - "quazepam": { - "name": "quazepam", - "properties": { - "bioavailability": "Oral 29-35%", - "summary": "Benzodiazepine derivate drug, noral is prescribed for short term treatment of insomnia, and sleep maintenance. its MOA is very similar to Ambien and Sonata and substitutes for those in animal studies.", - "onset": "10-30 minutes.", - "duration": "6-12 hours.", - "after-effects": "1-24 hours.", - "dose": "Light: 7.5-10mg Common: 10-15mg. Strong: 15-30mg.", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "dose_to_diazepam": "Quazepam - 20mg ~=10mg Diazepam.", - "aliases": [ - "doral" - ] - }, - "pretty_name": "Quazepam", - "aliases": [ - "doral" - ], - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "7.5-10mg", - "Common": "10-15mg.", - "Strong": "15-30mg." - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 279 - }, - "dom": { - "name": "dom", - "properties": { - "dose": "Oral Light: 1-2.5mg Common: 2.5-5mg Strong: 5-7.5mg Heavy: 7.5mg+", - "duration": "8-30 hours.", - "summary": "The most popular psychedelic amphetamine due to its pleasant effects, lower potency and shorter duration. Effects have been described as 'sillier' than LSD and related DOX chemicals", - "avoid": "marijuana (Can potentiate effects)", - "onset": "2-4 hours", - "effects": "visual distortions, a 'stoned' feeling, sense of well being.", - "detection": "DOM is a substituted amphetamine, so it can cause you to test positive for amphetamines 3 to 7 days after dosing.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "common" - ], - "after-effects": "12-24 hours.", - "aliases": [ - "stp" - ] - }, - "pretty_name": "DOM", - "aliases": [ - "stp" - ], - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "1-2.5mg", - "Common": "2.5-5mg", - "Strong": "5-7.5mg", - "Heavy": "7.5mg+" - } - }, - "formatted_duration": { - "value": "8-30", - "_unit": "hours" - }, - "formatted_onset": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_effects": [ - "visual distortions", - "a 'stoned' feeling", - "sense of well being", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DOM.shtml" - }, - "formatted_aftereffects": { - "value": "12-24", - "_unit": "hours" - }, - "id": 280 - }, - "nitracaine": { - "name": "nitracaine", - "properties": { - "dose": "Oral Low: 100mg Common: 100-150mg Strong: 150-175mg+ | Insufflated Light: 20-30mg Common: 30-40mg Strong: 50mg+", - "duration": "Insufflated: 2-4 hours | Oral: 3-5 hours.", - "summary": "An analogue of dimethocaine with local anaesthetic and stimulant properties, marketed in the RC scene as a Cocaine replacement. Has not seen widespread popularity.", - "onset": "Oral: 10-30 minutes. | Insufflated: 5-10 minutes", - "categories": [ - "stimulant", - "tentative", - "habit-forming" - ] - }, - "pretty_name": "Nitracaine", - "categories": [ - "stimulant", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Low": "100mg", - "Common": "100-150mg", - "Strong": "150-175mg+" - }, - "Insufflated": { - "Light": "20-30mg", - "Common": "30-40mg", - "Strong": "50mg+" - } - }, - "formatted_duration": { - "Insufflated": "2-4", - "Oral": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "id": 281 - }, - "2c-n": { - "name": "2c-n", - "properties": { - "aliases": [ - "2cn" - ], - "duration": "4-6 hours.", - "onset": "15-45 minutes.", - "after-effects": "2-4 hours.", - "dose": "Light: 100mg Common: 100-125mg Strong: 125-150mg+", - "summary": "A relatively uncommon and short-acting psychedelic phenethylamine of the 2C-x family. It behaves much like other 2C-x drugs, but is unique in that it is a yellowish golden-coloured salt. Described by some, namely Shulgin, as being quite underwhelming.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "2C-N", - "aliases": [ - "2cn" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "100mg", - "Common": "100-125mg", - "Strong": "125-150mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CN.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal034.shtml" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 282 - }, - "afloqualone": { - "name": "afloqualone", - "properties": { - "dose": "Low: 50-75mg Common: 75-100mg Strong: 100-200mg+", - "onset": "<60 minutes.", - "duration": "3-5 hours.", - "summary": "A rare analogue of methaqualone, a sedative, intoxicating drug. Similar effects to benzodiazepines, barbiturates and alcohol. Never widely used due to photosensitivity and skin irritation issues, though it has seem some popularity in Japan.", - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-3 hours." - }, - "pretty_name": "Afloqualone", - "categories": [ - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Low": "50-75mg", - "Common": "75-100mg", - "Strong": "100-200mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-3", - "_unit": "hours" - }, - "id": 283 - }, - "nitrous": { - "name": "nitrous", - "properties": { - "summary": "Nitrous oxide, also known as laughing gas, often inhaled through balloons filled with canisters of the gas.. A short-acting dissociative inhalant with strong visual, mental and auditory effects. Extremely popular especially in combination with other drugs.", - "duration": "1-5 minutes", - "onset": "0-1 minutes", - "after-effects": "15-30 minutes", - "effects": "giggling, mood lift, euphoria, sound distortion, dream like state, minor to strong hallucinations, reduction of external stimuli, analgesia, buzzing sensation in nerve, clumsiness, nausea, headaches, numbness in extremities", - "aliases": [ - "laughing_gas", - "n20", - "n2o", - "nos" - ], - "categories": [ - "dissociative", - "habit-forming", - "common" - ] - }, - "pretty_name": "N2O", - "aliases": [ - "laughing_gas", - "n20", - "n2o", - "nos" - ], - "categories": [ - "dissociative", - "habit-forming", - "common" - ], - "formatted_duration": { - "value": "1-5", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "giggling", - "mood lift", - "euphoria", - "sound distortion", - "dream like state", - "minor to strong hallucinations", - "reduction of external stimuli", - "analgesia", - "buzzing sensation in nerve", - "clumsiness", - "nausea", - "headaches", - "numbness in extremities" - ], - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Changes in felt bodily form": "https://psychonautwiki.org/wiki/Changes_in_felt_bodily_form", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Laughter": "https://psychonautwiki.org/wiki/Laughter", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Suggestibility enhancement": "https://psychonautwiki.org/wiki/Suggestibility_enhancement", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness" - }, - "formatted_aftereffects": { - "value": "15-30", - "_unit": "minutes" - }, - "sources": { - "_general": [ - "Ketamine potentiates cerebrocortical damage induced by the common anaesthetic agent nitrous oxide in adult rats - http://www.ncbi.nlm.nih.gov/pubmed/10928976", - "Severe neurotoxicity following intrathecal methotrexate with nitrous oxide sedation in a child with acute lymphoblastic leukemia - http://www.ncbi.nlm.nih.gov/pubmed/25360802", - "Neurologic degeneration associated with nitrous oxide anesthesia in patients with vitamin B12 deficiency - http://www.ncbi.nlm.nih.gov/pubmed/8250714" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Low Risk & Synergy" - }, - "nbomes": { - "status": "Low Risk & Synergy" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Low Risk & Synergy" - }, - "amt": { - "status": "Low Risk & Synergy" - }, - "5-meo-xxt": { - "status": "Low Risk & Synergy" - }, - "cannabis": { - "status": "Low Risk & Synergy" - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & Synergy" - }, - "pcp": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Low Risk & Synergy" - }, - "mdma": { - "status": "Low Risk & Synergy" - }, - "cocaine": { - "status": "Low Risk & Synergy" - }, - "caffeine": { - "status": "Low Risk & No Synergy" - }, - "alcohol": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely." - }, - "ghb/gbl": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely." - }, - "opioids": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely." - }, - "tramadol": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely." - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Low Risk & No Synergy" - }, - "ssris": { - "status": "Low Risk & No Synergy" - } - }, - "id": 284 - }, - "mxe": { - "name": "mxe", - "properties": { - "summary": "A popular dissociative drug which is an analogue of ketamine, though less sedating and more potent by weight, with a subjectively more 'complicated' set of effects.", - "dose": "Insufflated Threshold: 5-10mg Light: 10-20mg Common: 20-35mg Strong: 35-60mg Heavy: 60mg+ M-Hole: 70mg+ | Oral Threshold: 10-15mg Light: 15-25mg Common: 25-35 Strong: 40-65mg M-Hole: 75mg+ | Sublingual Threshold: 5-10mg Low: 10-20mg Common: 40-60mg Strong: 60-75mg M-Hole: 75-100mg | NOTE: Bodyweight plays a slight factor in MXE dosing, these are values for a 175lb (80kg) male", - "onset": "Insufflated: 5-20 minutes | Oral: 30-60 minutes | Sublingual: 15-45 minutes", - "duration": "3-6 hours", - "after-effects": "2-48 hours", - "avoid": "Alcohol, Benzodiazepines, Opioids, Other CNS depressants, including substances that have an effect on Serotonin (For example, yet not limited to MDMA, Amphetamine, and other stimulants)", - "aliases": [ - "methoxetamine", - "3-meo-2'oxo-pce" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "legality": "Methoxetamine is illegal in the US states Arizona, Florida, Indiana, Louisiana, Minnesota, North Dakota, Ohio and Virginia. It is also banned in Brazil, France, Germany, Japan, Russia and the UK." - }, - "pretty_name": "MXE", - "aliases": [ - "methoxetamine", - "3-meo-2'oxo-pce" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Insufflated": { - "Threshold": "5-10mg", - "Light": "10-20mg", - "Common": "20-35mg", - "Strong": "35-60mg", - "Heavy": "60mg+", - "M-Hole": "70mg+" - }, - "Oral": { - "Threshold": "10-15mg", - "Light": "15-25mg", - "Common": "25-35", - "Strong": "40-65mg", - "M-Hole": "75mg+" - }, - "Sublingual": { - "Threshold": "5-10mg", - "Low": "10-20mg", - "Common": "40-60mg", - "Strong": "60-75mg", - "M-Hole": "75-100mg" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "5-20", - "Oral": "30-60", - "Sublingual": "15-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methoxetamine_.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Mania": "https://psychonautwiki.org/wiki/Mania", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection", - "Visual sliding": "https://psychonautwiki.org/wiki/Visual_sliding" - }, - "formatted_aftereffects": { - "value": "2-48", - "_unit": "hours" - }, - "dose_note": " NOTE: Bodyweight plays a slight factor in MXE dosing, these are values for a 175lb (80kg) male", - "sources": { - "legality": [ - "http://www.azleg.gov/DocumentsForBill.asp?Session_ID=112&Bill_Number=HB2453", - "http://www.leg.state.fl.us/Statutes/index.cfm?App_mode=Display_Statute&URL=0800-0899/0893/0893.html", - "http://www.in.gov/legislative/ic/2010/title35/ar31.5/ch2.html", - "http://www.legis.la.gov/legis/ViewDocument.aspx?d=850979&n=HB10%20Act", - "https://www.revisor.mn.gov/statutes/?id=152.02", - "http://www.legis.nd.gov/cencode/t19c03-1.pdf?20140721032549", - "http://www.legislature.state.oh.us/BillText130/130_HB_315_RH_N.html", - "http://www.legislation.gov.uk/uksi/2013/239/contents/made" - ], - "_general": [ - "Methoxetamine associated reversible cerebellar toxicity: three cases with analytical confirmation. - http://www.ncbi.nlm.nih.gov/pubmed/22578175", - "Methoxetamine: from drug of abuse to rapid-acting antidepressant. - http://www.ncbi.nlm.nih.gov/pubmed/22819129", - "From Special K to Special M: the evolution of the recreational use of ketamine and methoxetamine. - http://www.ncbi.nlm.nih.gov/pubmed/23421859", - "Ketamine-derived designer drug methoxetamine: metabolism including isoenzyme kinetics and toxicological detectability using GC-MS and LC-(HR-)MSn - http://www.ncbi.nlm.nih.gov/pubmed/23774830", - "Three months of methoxetamine administration is associated with significant bladder and renal toxicity in mice. - http://www.ncbi.nlm.nih.gov/pubmed/24580056", - "Analytical findings of an acute intoxication after inhalation of methoxetamine. - http://www.ncbi.nlm.nih.gov/pubmed/24904014", - "Acute methoxetamine and amphetamine poisoning with fatal outcome: a case report - http://www.ncbi.nlm.nih.gov/pubmed/25060403", - "From \"Special K\" to \"Special M\": the evolution of the recreational use of ketamine and methoxetamine. - http://www.ncbi.nlm.nih.gov/pubmed/23421859", - "Ketamine-derived designer drug methoxetamine: metabolism including isoenzyme kinetics and toxicological detectability using GC-MS and LC-(HR-)MSn. - http://www.ncbi.nlm.nih.gov/pubmed/23774830", - "Acute methoxetamine and amphetamine poisoning with fatal outcome: a case report. - http://www.ncbi.nlm.nih.gov/pubmed/25060403~adddrugsource cannabis general Cannabis use in relation to obesity and insulin resistance in the Inuit population. - https://www.ncbi.nlm.nih.gov/pubmed/25557382", - "3 case reports of toxicity due to recreational use of MXE - http://link.springer.com/article/10.1007/s00228-011-1199-9" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Caution", - "note": "As an NMDA antagonist MXE potentiates DOx which can be unpleasantly intense" - }, - "nbomes": { - "status": "Caution", - "note": "As an NMDA antagonist MXE potentiates NBOMes which can be unpleasantly intense" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Caution" - }, - "amt": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Low Risk & Synergy", - "note": "Little information exists about this combination." - }, - "cannabis": { - "status": "Low Risk & Synergy" - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & No Synergy" - }, - "pcp": { - "status": "Caution", - "note": "There are no reports available about this combination" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "Risk of tachycardia, hypertension, and manic states" - }, - "mdma": { - "status": "Caution", - "note": "There have been reports of risky serotonergic interactions when the two are taken at the same time, but MXE taken to the end of an MDMA experience does not appear to cause the same issues." - }, - "cocaine": { - "status": "Caution", - "note": "Stimulants taken with MXE can lead to hypermanic states much more easily, especially if sleep is avoided." - }, - "caffeine": { - "status": "Low Risk & No Synergy", - "note": "No likely interactions" - }, - "alcohol": { - "status": "Dangerous", - "note": "There is a high risk of memory loss, vomiting and severe ataxia from this combination." - }, - "ghb/gbl": { - "status": "Dangerous", - "note": "Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the patient falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position." - }, - "opioids": { - "status": "Dangerous", - "note": "This combination can potentiate the effects of the opioid" - }, - "tramadol": { - "status": "Dangerous" - }, - "benzodiazepines": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess." - }, - "benzos": { - "status": "Caution", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess." - }, - "maois": { - "status": "Unsafe", - "note": "MAO-B inhibitors appear to increase the potency of MXE. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available" - }, - "ssris": { - "status": "Caution", - "note": "Depending on the SSRI this combination can be unpredictable" - } - }, - "id": 285 - }, - "a-pvp": { - "name": "a-pvp", - "properties": { - "dose": "Light: 5-10mg Common: 10-25mg Heavy: 25-50mg+", - "aliases": [ - "alpha-pvp", - "apvp", - "alpha-Pyrrolidinopentiophenone", - "flocka", - "flakka", - "α-pvp", - "αpvp" - ], - "summary": "A potent, short-lasting pyrovalerone-type stimulant which became popular despite often being said to not be particularly euphoric, perhaps due to its propensity to cause compulsive redosing. Effects should be similar to MDPV.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "duration": "2-5 hours.", - "onset": "5-15 minutes.", - "after-effects": "1-48 hours." - }, - "pretty_name": "α-PVP", - "aliases": [ - "alpha-pvp", - "apvp", - "alpha-Pyrrolidinopentiophenone", - "flocka", - "flakka", - "α-pvp", - "αpvp" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-25mg", - "Heavy": "25-50mg+" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_aPVP.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Ego inflation": "https://psychonautwiki.org/wiki/Ego_inflation", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Vibrating vision": "https://psychonautwiki.org/wiki/Vibrating_vision", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-48", - "_unit": "hours" - }, - "id": 286 - }, - "4-fpm": { - "name": "4-fpm", - "properties": { - "summary": "Seems to be a substance, that was just made to get money. High doses needed to feel any effects. Would avoid.", - "categories": [ - "research-chemical" - ] - }, - "pretty_name": "4-FPM", - "categories": [ - "research-chemical" - ], - "formatted_onset": { - "Oral": "60-90", - "Insufflated": "20-40", - "_unit": "minutes" - }, - "id": 287 - }, - "α-pbp": { - "name": "α-pbp", - "properties": { - "summary": "Stimulant that is the homologue between α-PPP and α-PVP.", - "dose": "Oral Light: 10-25mg Common: 25-50mg Strong: 50mg+", - "onset": "20-35 minutes", - "duration": "3-4 hours", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "a-pbp", - "alpha-pbp" - ], - "after-effects": "1-24 hours." - }, - "pretty_name": "α-PBP", - "aliases": [ - "a-pbp", - "alpha-pbp" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50mg+" - } - }, - "formatted_duration": { - "value": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-35", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 288 - }, - "atomoxetine": { - "name": "atomoxetine", - "properties": { - "summary": "A NRI that is used for ADHD. With a quite odd pharmacological background.", - "categories": [ - "tentative" - ], - "aliases": [ - "strattera" - ], - "dose": "Oral Light: 10-18mg Common: 18-40mg Strong: 40-80mg+", - "onset": "15-45 minutes.", - "duration": "8-12 hours.", - "after-effects": "2-24 hours.", - "bioavailability": "Oral: 63-94%." - }, - "pretty_name": "Atomoxetine", - "aliases": [ - "strattera" - ], - "categories": [ - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-18mg", - "Common": "18-40mg", - "Strong": "40-80mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 289 - }, - "theacrine": { - "name": "theacrine", - "properties": { - "summary": "Small alkaloid which can be seen as a structurally modified version of caffeine, with similar stimulating effects. It also shares anti-inflammatory and analgesic effects with caffeine.", - "onset": "15-30 minutes.", - "dose": "Oral Light: 10-25mg Common: 25-50mg Strong: 50-100mg+", - "duration": "2-6 hours.", - "categories": [ - "stimulant", - "nootropic" - ] - }, - "pretty_name": "Theacrine", - "categories": [ - "stimulant", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-100mg+" - } - }, - "formatted_duration": { - "value": "2-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "id": 290 - }, - "dehydroxyfluorafinil": { - "name": "dehydroxyfluorafinil", - "properties": { - "summary": "Nootropic of the benzhydryl class. Closely related to Adrafinil and Modafinil. Was branded as \"Modafiendz\" through some research chemical vendors.", - "aliases": [ - "modafiendz" - ], - "dose": "Threshold 25-50mg Light: 50-100mg Common: 100-150mg Strong: 150-200mg+", - "duration": "5-8 hours.", - "onset": "30-60 minutes.", - "after-effects": "2-24 hours.", - "categories": [ - "stimulant", - "nootropic", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "Dehydroxyfluorafinil", - "aliases": [ - "modafiendz" - ], - "categories": [ - "stimulant", - "nootropic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Threshold": { - "Light": "50-100mg", - "Common": "100-150mg", - "Strong": "150-200mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 291 - }, - "homosildenafil": { - "name": "homosildenafil", - "properties": { - "summary": "An analogue of sildenafil (viagra) with similar effects. Has been missold in certain 'herbal' blends and dietary supplements for sexual potency. Little is known about the pharmacology or safety profile of this drug in humans, potentially less potent than sildenafil.", - "dose": "Oral Light: 10-25mg Common: 25-50mg Strong: 50-100mg", - "duration": "5-9 hours.", - "oral": "Light: 10-25mg Common: 25-50mg Strong: 50-100mg.", - "categories": [ - "research-chemical" - ] - }, - "pretty_name": "Homosildenafil", - "categories": [ - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-100mg" - } - }, - "formatted_duration": { - "value": "5-9", - "_unit": "hours" - }, - "id": 292 - }, - "6-mapb": { - "name": "6-mapb", - "properties": { - "summary": "Empathogen drug that is structurally related to 6-APB and MDMA.", - "dose": "Oral Light: 20-40mg Common: 40-80mg Strong: 80-100mg | Insufflated Light: 10-20mg Common: 20-40mg Strong: 40-100mg+", - "onset": "Orally: Within an hour. | Insufflated: Within 15 minutes.", - "duration": "5-10 hours. Dependant on dose.", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "after-effects": "2-4 hours.", - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "6-MAPB", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "20-40mg", - "Common": "40-80mg", - "Strong": "80-100mg" - }, - "Insufflated": { - "Light": "10-20mg", - "Common": "20-40mg", - "Strong": "40-100mg+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "Orally": "Within", - "Insufflated": "Within", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_6MAPB.shtml" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 293 - }, - "l-theanine": { - "name": "l-theanine", - "properties": { - "summary": "An Amino acid that is structural similar to Glutamine. Most report it as a relaxing agent without much sedation. Most commonly found tea. Usually mixed with Caffeine.", - "dose": "Common: 100-200mg.", - "onset": "10-30 minutes.", - "duration": "3-6 hours.", - "categories": [ - "common", - "supplement" - ], - "aliases": [ - "theanine" - ], - "after-effects": "1-2 hours." - }, - "pretty_name": "L-THEANINE", - "aliases": [ - "theanine" - ], - "categories": [ - "common", - "supplement" - ], - "formatted_dose": { - "Oral": { - "Common": "100-200mg." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "id": 294 - }, - "promethazine": { - "name": "promethazine", - "properties": { - "summary": "A first generation antihistamine, which also possesses anticholinergic, strong sedative and antipsychotic properties. Once commonly used as a treatment for psychosis, it is now more commonly seen as a component of codeine cough syrups as an anti-nausea agent.", - "dose": "Common: 25-75mg's. | NOTE: This is what is normally used in medicinal settings, and is usually what is prescribed to you, since it has anticholinergic properties; IE; Delirant.", - "onset": "15-30 minutes.", - "duration": "4-8 hours.", - "after-effects": "0-3 hours.", - "categories": [ - "common" - ] - }, - "pretty_name": "Promethazine", - "categories": [ - "common" - ], - "formatted_dose": { - "Common:": { - "Common": "25-75mg" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "0-3", - "_unit": "hours" - }, - "dose_note": " NOTE: This is what is normally used in medicinal settings, and is usually what is prescribed to you, since it has anticholinergic properties; IE; Delirant.", - "id": 295 - }, - "mcpp": { - "name": "mcpp", - "properties": { - "summary": "A phenylpiperazine stimulant first developed in the 1970s before being sold in the RC market, often mislabelled as MDMA. Said to have very unpleasant effects such as anxiogenesis and headaches.", - "onset": "Oral: >60 minutes. Insufflated: >30 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "MCPP", - "categories": [ - "stimulant", - "research-chemical", - "tentative" - ], - "formatted_onset": { - "60": "minutes.", - "_unit": "minutes" - }, - "id": 296 - }, - "dramamine": { - "name": "dramamine", - "properties": { - "summary": "A combination of diphenhydramine and a mild stimulant to counteract the drowsiness accompanied by typical medical use of diphenhydramine. Roughly half the potency of DPH. Small doses can relieve motion sickness, reduce body load from opioids or DXM. Becomes a deliriant in high doses, keeping the user awake and often causing dysphoric, realistic hallucinations.", - "dose": "Oral Light: 100-250mg Common: 250mg-400mg Strong: 400mg-600mg+ | NOTE: since this is a delirant, we advise against taking it, yet we can't stop you from ingesting it.", - "onset": "30-90 minutes", - "duration": "5-8 hours.", - "categories": [ - "depressant", - "deliriant", - "common" - ], - "effects": "Delirium, Dream-Like-Experiences, Paranoia, Visual and audio distortions, dry mouth, muscle cramps, Nausea, Dysphoria, Tremors.", - "avoid": "A fair amount of oral dramamine preparations contain NSAID's Which can be toxic to your liver at high doses.", - "aliases": [ - "dimenhydrinate", - "gravol" - ] - }, - "pretty_name": "Dimenhydrinate", - "aliases": [ - "dimenhydrinate", - "gravol" - ], - "categories": [ - "depressant", - "deliriant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "100-250mg", - "Common": "250mg-400mg", - "Strong": "400mg-600mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Delirium", - "Dream-Like-Experiences", - "Paranoia", - "Visual and audio distortions", - "dry mouth", - "muscle cramps", - "Nausea", - "Dysphoria", - "Tremors", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Dimenhydrinate.shtml" - }, - "dose_note": " NOTE: since this is a delirant, we advise against taking it, yet we can't stop you from ingesting it.", - "id": 297 - }, - "etodesnitazene": { - "name": "etodesnitazene", - "properties": { - "draft": "draft", - "aliases": [ - "etazene" - ] - }, - "pretty_name": "Etodesnitazene", - "aliases": [ - "etazene" - ], - "id": 298 - }, - "fluclotizolam": { - "name": "fluclotizolam", - "properties": { - "summary": "A derivative of Etizolam. There are conflicting reports on its dosage, though claims have been made that it is approximately 3x the potency of Etizolam, with a shorter half-life.", - "onset": "10-30 minutes.", - "dose": "Oral Light: 250ug Common: 250-500ug Strong: 500-750ug Heavy: 750ug+ | Note: These doses are extremely tentative and will vary from user to user depending on many factors including but not limited to tolerance.", - "categories": [ - "benzodiazepine", - "tentative", - "research-chemical", - "habit-forming" - ], - "duration": "3-6 hours.", - "after-effects": "1-14 hours." - }, - "pretty_name": "Fluclotizolam", - "categories": [ - "benzodiazepine", - "tentative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "250ug", - "Common": "250-500ug", - "Strong": "500-750ug", - "Heavy": "750ug+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-14", - "_unit": "hours" - }, - "dose_note": " Note: These doses are extremely tentative and will vary from user to user depending on many factors including but not limited to tolerance.", - "id": 299 - }, - "phenibut": { - "name": "phenibut", - "properties": { - "onset": "30-120 mins to feel it, peak around t+3-4h", - "duration": "9-16 hours.", - "dose": "Light: 300-600mg's Common: 600-1200mg Strong: 1200-1800mg+ | NOTE: This substance has a very fast tolerance raise, and also seems to vary a lot person to person. Start low and work your way up. We would recommend starting with a low dose and working it up every 50-100mg's every two weeks.", - "summary": "A derivative of GABA with the addition of a phenyl ring which allows it to cross the Blood Brain Barrier. Is mostly used as an anti-anxiety and anti-insomnia medication. Tolerance and physical dependency builds very quickly.", - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "nootropic" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-24 hours.", - "avoid": "Other CNS depressants such as alcohol" - }, - "pretty_name": "Phenibut", - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "nootropic" - ], - "formatted_dose": { - "Light:": { - "Light": "300-600mg", - "Common": "600-1200mg", - "Strong": "1200-1800mg+" - } - }, - "formatted_duration": { - "value": "9-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle cramps": "https://psychonautwiki.org/wiki/Muscle_cramps", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Stomach cramps": "https://psychonautwiki.org/wiki/Stomach_cramps", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " NOTE: This substance has a very fast tolerance raise, and also seems to vary a lot person to person. Start low and work your way up. We would recommend starting with a low dose and working it up every 50-100mg's every two weeks.", - "id": 300 - }, - "truffles": { - "name": "truffles", - "properties": { - "summary": "Truffles (magic truffles, sclerotium) are the thickened root sections of magic mushrooms. Like magic mushrooms, Truffles contain the psycho-active chemicals psilocybin and psilocin. See mushrooms for more information.", - "onset": "30-60 minutes", - "duration": "3-6 hours", - "dose": "Wet Light: 5g, Common: 10g, Heavy: 15g+ | Dry Light: 0.5-1.5g Common: 1.5-4g Heavy: 4g+", - "categories": [ - "psychedelic" - ], - "effects": "visual distortion, color enhancement, sense of conection with nature, sense of well being, sense of wonder, closed eye visuals, tactile enhancement", - "after-effect": "1-12 hours." - }, - "pretty_name": "Truffles", - "categories": [ - "psychedelic" - ], - "formatted_dose": { - "Wet": { - "Light": "5g", - "Common": "10g", - "Heavy": "15g+" - }, - "Dry": { - "Light": "0.5-1.5g", - "Common": "1.5-4g", - "Heavy": "4g+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "visual distortion", - "color enhancement", - "sense of conection with nature", - "sense of well being", - "sense of wonder", - "closed eye visuals", - "tactile enhancement" - ], - "dose_note": " NOTE: Dry truffles will be several times more potent", - "id": 301 - }, - "methylmethaqualone": { - "name": "methylmethaqualone", - "properties": { - "summary": "A more potent analogue of methaqualone with a short duration. Thought to be potentially neurotoxic. Has pro-convulsive effects.", - "after-effects": "1-2 hours.", - "dose": "Vapourized/Sublingual Threshold: 2-3mg Light: 3-5mg Common: 5-10mg. Strong: 10-20mg+ | NOTE: Remember this substance is known to cause seizures, take much caution with this.", - "onset": "Sublingual: 10 minutes | Vapourized: 0-1 minutes.", - "categories": [ - "depressant", - "research-chemical", - "habit-forming" - ], - "aliases": [ - "mmq" - ], - "duration": "1-2 hours", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic." - }, - "pretty_name": "Methylmethaqualone", - "aliases": [ - "mmq" - ], - "categories": [ - "depressant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Vapourized/Sublingual": { - "Threshold": "2-3mg", - "Light": "3-5mg", - "Common": "5-10mg.", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "value": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Sublingual": "10", - "Vapourized": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methylmethaqualone.shtml" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "dose_note": " NOTE: Remember this substance is known to cause seizures, take much caution with this.", - "id": 302 - }, - "gbl": { - "name": "gbl", - "properties": { - "summary": "A pro-drug to GHB whose rapid absorption leads it to have a faster onset and shorter duration. Used in a similar manner to GHB, as a less-toxic alternative to alcohol. Consume slowly instead of as a \"shot\" to hugely improve safety and reduce overdose risk.", - "duration": "1-2 hours", - "avoid": "Alcohol, other depressants.", - "effects": "relaxation, mood lift, happiness, sociability, increased sex drive, lowered inhibitions, analgesia, dystaxia, drowsiness, sleep, amnesia", - "onset": "10-30 minutes", - "dose": "Oral Light: 0.3-0.9ml Common: 0.6-1.5ml Strong: 1.2-2ml Heavy: 2-3ml Dangerous: 5ml+ | NOTE: 1ml = 1.6g GHB. Tends to induce heavy sleep as you pass the 2ml mark.", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "after-effects": "1-2 hours" - }, - "pretty_name": "GBL", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "0.3-0.9ml", - "Common": "0.6-1.5ml", - "Strong": "1.2-2ml", - "Heavy": "2-3ml", - "Dangerous": "5ml+" - } - }, - "formatted_duration": { - "value": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "relaxation", - "mood lift", - "happiness", - "sociability", - "increased sex drive", - "lowered inhibitions", - "analgesia", - "dystaxia", - "drowsiness", - "sleep", - "amnesia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_GBL.shtml" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "dose_note": " NOTE: 1ml = 1.6g GHB. Tends to induce heavy sleep as you pass the 2ml mark.", - "id": 303 - }, - "4-fluoroethylphenidate": { - "name": "4-fluoroethylphenidate", - "properties": { - "summary": "A more potent and longer lasting analogue of Ethylphenidate.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "4f-eph", - "4-feph" - ], - "dose": "Light: 5-10mg Common: 10-30mg Strong: 30-50mg+", - "duration": "5-6 hours.", - "after-effects": "1-12 hours.", - "onset": "10-25 minutes." - }, - "pretty_name": "4-Fluoroethylphenidate", - "aliases": [ - "4f-eph", - "4-feph" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-30mg", - "Strong": "30-50mg+" - } - }, - "formatted_duration": { - "value": "5-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-25", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 304 - }, - "3-meomc": { - "name": "3-meomc", - "properties": { - "summary": "A cathinone that has a short history of human use.", - "dose": "Insufflated Light: 25-50mg Common: 50-100mg Strong: 100-150mg+", - "onset": "Insufflated: 10-20 minutes.", - "duration": "5-7 hours.", - "avoid": "Other stimulants.", - "categories": [ - "stimulant", - "habit-forming", - "empathogen" - ] - }, - "pretty_name": "3-MeOMC", - "categories": [ - "stimulant", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Insufflated": { - "Light": "25-50mg", - "Common": "50-100mg", - "Strong": "100-150mg+" - } - }, - "formatted_duration": { - "value": "5-7", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "10-20", - "_unit": "minutes" - }, - "id": 305 - }, - "4-chlorodiazepam": { - "name": "4-chlorodiazepam", - "properties": { - "summary": "A benzodiazepine derivative of Diazepam, yet lacks affinity for GABA(a) receptors, yet is still a sedative, that has pro-convulsant effects. Yet at lower doses it has been proven to be neuroprotective.", - "aliases": [ - "ro5-4864", - "4'-chlorodiazepam" - ], - "categories": [ - "research-chemical", - "tentative" - ] - }, - "pretty_name": "4-CHLORODIAZEPAM", - "aliases": [ - "ro5-4864", - "4'-chlorodiazepam" - ], - "categories": [ - "research-chemical", - "tentative" - ], - "id": 306 - }, - "hydroxyzine": { - "name": "hydroxyzine", - "properties": { - "summary": "An antihistamine drug commonly prescribed for anxiety, itchiness, nausea, and insomnia. Hydroxyzine has also been used to potentiate the analgesia of opioids as well as diminishing the negative effects of opioids, such as itchiness.", - "aliases": [ - "vistaril", - "atarax" - ], - "onset": "20-60 minutes.", - "duration": "3-5 hours.", - "dose": "Oral Common: 25-100mg", - "categories": [ - "depressant", - "deliriant" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Hydroxyzine", - "aliases": [ - "vistaril", - "atarax" - ], - "categories": [ - "depressant", - "deliriant" - ], - "formatted_dose": { - "Oral": { - "Common": "25-100mg" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Hydroxyzine.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 307 - }, - "4-meo-butryfentanyl": { - "name": "4-meo-butryfentanyl", - "properties": { - "summary": "Rare and basically unknown opioid and fentanyl analogue (not to be confused with Butyrfentanyl). Virtually no reliable information exists, safe dosages are unknown. Exercise extreme caution. Overdose may result in respiratory depression. Do not mix with stimulants or depressants.", - "onset": "Oral: 5-15 minutes. | Insufflated: 1-2 minutes.", - "duration": "Oral: 45-120 minutes. | Insufflated: 30-75 minutes.", - "aliases": [ - "4-meo-bf" - ], - "categories": [ - "tentative", - "research-chemical", - "opioid", - "habit-forming" - ], - "after-effects": "1-2 hours." - }, - "pretty_name": "4-MeO-Butyrfentanyl", - "aliases": [ - "4-meo-bf" - ], - "categories": [ - "tentative", - "research-chemical", - "opioid", - "habit-forming" - ], - "formatted_duration": { - "Oral": "45-120", - "Insufflated": "30-75", - "_unit": "minutes" - }, - "formatted_onset": { - "Oral": "5-15", - "Insufflated": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "id": 308 - }, - "25b-nbome": { - "name": "25b-nbome", - "properties": { - "summary": "Psychedelic Phenethylamine, active in the lower microgram range, that is not active orally.", - "dose": "Sublingual Threshold: 100ug Light: 100-300ug Common: 350-500ug Strong: 500-700ug+ | Insufflated Threshold: 50ug Light: 50-200ug Common: 200-350ug Strong: 350-500+ | Note: Do not exceed 1500ug.", - "onset": "Sublingual: 20-40 minutes. | Insufflated 2-5 minutes.", - "duration": "8-12 hours.", - "after-effects": "2-6 hours.", - "marquis": "Dark Green.", - "aliases": [ - "25b" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "a": "common bomamine analogue of 2C-B. Extremely potent psychedelic with stimulating qualities. May cause potentially dangerous vasoconstriction at high doses. May induce uncomfortable body load.", - "test-kits": "Marquis: Dark Green. | Mecke: Dark Green. | Mandelin: Red and Green. | Froehde: Yellow | Liebermann: Yellow > Black. | Ehrlich's Reagent: No colour change." - }, - "pretty_name": "25B-NBOMe", - "aliases": [ - "25b" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "100ug", - "Light": "100-300ug", - "Common": "350-500ug", - "Strong": "500-700ug+" - }, - "Insufflated": { - "Threshold": "50ug", - "Light": "50-200ug", - "Common": "200-350ug", - "Strong": "350-500+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "Sublingual": "20-40", - "Insufflated": "2-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_25BNBOMe.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Sublingual numbing": "https://psychonautwiki.org/wiki/Sublingual_numbing", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "dose_note": " Note: Do not exceed 1500ug.", - "id": 309 - }, - "3-fea": { - "name": "3-fea", - "properties": { - "summary": "A novel fluorinated amphetamine with serotonergic properties. Effects are similar to 4-FA, in that it provides slight dopamine and norepinephrine release or reuptake inhibition, as well as serotonin release and reuptake inhibition. Effects on the serotonin side are more pronounced than dopamine and norepinephrine, the latter two being almost negligibly.", - "dose": "Oral Light: 10-30mg Common: 30-50mg Strong: 50-70mg+", - "onset": "20-50 minutes.", - "duration": "4-6 hours.", - "after-effects": "1-12 hours.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ] - }, - "pretty_name": "3-FEA", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-30mg", - "Common": "30-50mg", - "Strong": "50-70mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-50", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 310 - }, - "ept": { - "name": "ept", - "properties": { - "summary": "Ethylpropyltryptamine a novel tryptamine, that is the structural homologue of DMT.", - "onset": "Oral: 20-60 minutes. | Insufflated: 5-20 minutes.", - "duration": "Oral: 2-4 hours. | Insufflated: 1-3 hours.", - "dose": "Oral Light: 50-75mg Common: 75-100mg Strong: 100mg+", - "after-effects": "Oral: 1-6 hours. | Insufflated: 1-4 hours.", - "aliases": [ - "ethylpropyltryptamine", - "n,n-ethylpropyltryptamine" - ], - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "EPT", - "aliases": [ - "ethylpropyltryptamine", - "n,n-ethylpropyltryptamine" - ], - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "50-75mg", - "Common": "75-100mg", - "Strong": "100mg+" - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-60", - "Insufflated": "5-20", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "1-6", - "Insufflated": "1-4", - "_unit": "hours" - }, - "id": 311 - }, - "5-meo-mipt": { - "name": "5-meo-mipt", - "properties": { - "dose": "Threshold: 0.5mg-1mg Light: 1-3mg Common: 4-8mg Strong: 8-12mg+.", - "onset": "<30 minutes.", - "duration": "3-7 hours.", - "summary": "A potent, stimulating psychedelic tryptamine, sometimes compared to 5-MeO-DiPT. Has an unusually strong body component and weak visual effects. Often said to be very empathogenic.", - "after-effects": "2-10 hours", - "categories": [ - "psychedelic", - "research-chemical", - "empathogen", - "common" - ], - "aliases": [ - "5meomipt", - "moxy", - "5meo-mipt" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "5-MeO-MiPT", - "aliases": [ - "5meomipt", - "moxy", - "5meo-mipt" - ], - "categories": [ - "psychedelic", - "research-chemical", - "empathogen", - "common" - ], - "formatted_dose": { - "Oral": { - "Threshold": "0.5mg-1mg", - "Light": "1-3mg", - "Common": "4-8mg", - "Strong": "8-12mg+." - } - }, - "formatted_duration": { - "value": "3-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeOMIPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal40.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Stomach bloating": "https://psychonautwiki.org/wiki/Stomach_bloating", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "2-10", - "_unit": "hours" - }, - "id": 312 - }, - "25d-nbome": { - "name": "25d-nbome", - "properties": { - "summary": "Uncommon analogue of 2C-D. Extremely potent psychedelic with stimulating qualities. Could cause dangerous vasoconstriction at high doses. May induce uncomfortable body load.", - "dose": "Sublingual Threshold: 100-300ug. Light: 300-500ug. Common: 500-1000ug Strong: 1000-1250ug+ | Note: Do not exceed 1500ug.", - "duration": "4-6 hours.", - "aliases": [ - "2c-d-nbome", - "25d" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "onset": "20-40 minutes.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "6-24 hours.", - "test-kits": "Marquis: Orange > Red. | Mecke: Brown > Green. | Mandelin: Red and Green. | Liebermann: Yellow > Black. | Simon's: Red > Brown. | Ehrlich: No colour change." - }, - "pretty_name": "25D-NBOMe", - "aliases": [ - "2c-d-nbome", - "25d" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "100-300ug.", - "Light": "300-500ug.", - "Common": "500-1000ug", - "Strong": "1000-1250ug+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_25DNBOMe.shtml" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "dose_note": " Note: Do not exceed 1500ug.", - "id": 313 - }, - "5-it": { - "name": "5-it", - "properties": { - "duration": "8-12 hours.", - "aliases": [ - "5-api" - ], - "summary": "An empathogenic stimulant with a very long duration, prone to cause overheating and potentially quite dangerous. Related to αMT, though described as being less psychedelic and with much stronger stimulating effects.", - "onset": "90-120 minutes.", - "dose": "Oral Light: 50mg Common: 50-100mg Strong: 100-150mg+", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "after-effects": "1-48 hours." - }, - "pretty_name": "5-IT", - "aliases": [ - "5-api" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "50mg", - "Common": "50-100mg", - "Strong": "100-150mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "90-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5IT.shtml" - }, - "formatted_aftereffects": { - "value": "1-48", - "_unit": "hours" - }, - "id": 314 - }, - "parafluorobutyrfentanyl": { - "name": "parafluorobutyrfentanyl", - "properties": { - "onset": "Insufflated <5 minutes.", - "aliases": [ - "pfbf", - "4-fluorobutyrfentanyl", - "4-fbf" - ], - "duration": "30-60 minutes.", - "dose": "Low: 300ug Common: 600-900ug Strong: 900-1200ug.", - "summary": "Rare, little known and extremely potent RC analogue of Fentanyl. This powerful opioid is generally only dispensed as a nasal spray. Handle with extreme caution and never mix with other depressants.", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia." - }, - "pretty_name": "4-Fluorobutyrfentanyl", - "aliases": [ - "pfbf", - "4-fluorobutyrfentanyl", - "4-fbf" - ], - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Low": "300ug", - "Common": "600-900ug", - "Strong": "900-1200ug." - } - }, - "formatted_duration": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "Insufflated", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4Fluorobutyrfentanyl.shtml" - }, - "id": 315 - }, - "4-aco-dpt": { - "name": "4-aco-dpt", - "properties": { - "summary": "Research chemical of the Tryptamine class. First noted being sold in 2012, yet never recieved much attention. Conflicting reports. Doesn't dissolve well at all in nearly all solutions it was tested in.", - "onset": "Insufflated: 5-10 minutes.", - "duration": "Insufflated 60-120 minutes.", - "after-effects": "2-8 hours.", - "note": "It seems that everyone is in favour of taking this substance intranasally, due to a quite poor oral BA.", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "aliases": [ - "4acodpt" - ], - "avoid": "Please, don't mix this substance with another psychedelic/dissociative/stimulant. Respect drugs especially ones that have very few reports and may interact differently than the more common 4-subbed tryptamines.", - "dose": "Insufflated Light: 10-15mg Common: 15-25mg Strong: 25-35mg+" - }, - "pretty_name": "4-AcO-DPT", - "aliases": [ - "4acodpt" - ], - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Insufflated": { - "Light": "10-15mg", - "Common": "15-25mg", - "Strong": "25-35mg+" - } - }, - "formatted_duration": { - "value": "Insufflated", - "_unit": "minutes" - }, - "formatted_onset": { - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-8", - "_unit": "hours" - }, - "id": 316 - }, - "oxiracetam": { - "name": "oxiracetam", - "properties": { - "summary": "Oxiracetam is a racetam nootropic, having a hydroxyl group being the only difference between this and Piracetam. It used as a nootropic, namely for increased cognitive function. It is usually used two to three times a day. This substance is normally taken with Choline, can cause headaches without the addition of Choline.", - "dose": "Common: 1200-2400mg", - "duration": "4-6 hours.", - "onset": "15-30 minutes.", - "after-effects": "1-6 hours.", - "note": "The doses listed are for over the course of a 24 hour period. 2-3x daily, such as 400-800mg three times a day.", - "experiences": "https://erowid.org/experiences/subs/exp_Smarts_Oxiracetam.shtml", - "aliases": [ - "neuractiv", - "neuromet", - "hydroxypiracetam" - ] - }, - "pretty_name": "Oxiracetam", - "aliases": [ - "neuractiv", - "neuromet", - "hydroxypiracetam" - ], - "formatted_dose": { - "Oral": { - "Common": "1200-2400mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "dose_note": " Note: This is for the course over a 24 hour period. 2-3x times daily, such as 400mg-800mg/3x day.", - "id": 317 - }, - "bromadol": { - "name": "bromadol", - "properties": { - "summary": "A very potent opioid that has an arylcyclohexylamine structure. Intial studies estimated that it was ~10,000x Morphine in animal studies. However that value has since decreased to ~504 times the potency of morphine for the trans-isomer.", - "onset": "Insufflated: 5-15 minutes. | Intramuscular: 1-5 minutes. | Intravenous: 1-2 minutes.", - "duration": "Insufflated: 3-6 hours. | Intramuscular: 2-4 hours. | Intravenous: 1-3 hours.", - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ], - "aliases": [ - "bdpc" - ], - "avoid": "All other CNS depressants." - }, - "pretty_name": "Bromadol", - "aliases": [ - "bdpc" - ], - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_duration": { - "Insufflated": "3-6", - "Intramuscular": "2-4", - "Intravenous": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "5-15", - "Intramuscular": "1-5", - "Intravenous": "1-2", - "_unit": "minutes" - }, - "id": 318 - }, - "coronaridine": { - "name": "coronaridine", - "properties": { - "summary": "Alkaloid found in Tabernanthe iboga and related species. Persistently reduces the self-administration of Cocaine and Morphine in rats.", - "categories": [ - "psychedelic", - "tentative" - ] - }, - "pretty_name": "Coronaridine", - "categories": [ - "psychedelic", - "tentative" - ], - "sources": { - "_general": [ - "Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum. http://www.sciencedirect.com/science/article/pii/0006899394909482" - ] - }, - "id": 319 - }, - "pagoclone": { - "name": "pagoclone", - "properties": { - "summary": "An anxiolytic drug related to zopiclone with no sedative or hypnotic qualities. Has been investigated as a possible alcohol replacement. Related in structure and effect to Zopiclone and Zolpidem.", - "categories": [ - "depressant", - "habit-forming", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "Pagoclone", - "categories": [ - "depressant", - "habit-forming", - "tentative", - "research-chemical" - ], - "id": 320 - }, - "methadone": { - "name": "methadone", - "properties": { - "summary": "A synthetic opioid drug used as an analgesic and is often used in detoxification off of other opioids. As it has a much longer half-life.", - "onset": "45-120 minutes.", - "duration": "Oral 6-12 hours. NOTE: Can last much longer. Mostly dependant if using Chronically or not.", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "dose": "Light: 5-10mg Common: 10-20mg Strong: 20-35mg+ NOTE: these doses are not intended for opioid-naïve users. 40mg could be lethal for a naïve user. Always start low and titrate /slowly/", - "avoid": "All other CNS depressants", - "bioavailability": "Oral 75-97% (Mean 86%) | Rectal 70-81% (Mean 76%)", - "half-life": "12-18 hours on the first dose 13-47 on concurrent", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-48 hours." - }, - "pretty_name": "Methadone", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-35mg+", - "NOTE": "these" - } - }, - "formatted_duration": { - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methadone.shtml" - }, - "formatted_aftereffects": { - "value": "1-48", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Methadone trials have proven successful in treating Heroin addiction - http://jamanetwork.com/journals/jama/article-abstract/656315" - ] - }, - "id": 321 - }, - "delorazepam": { - "name": "delorazepam", - "properties": { - "summary": "Also known as chlordesmethyldiazepam, this uncommon benzodiazepine compound is primarily used for treatment of anxiety and alcohol withdrawal, due to its long half-life (60-140 hours). It is also the active metabolite of diclazepam and cloxazolam.", - "dose": "Oral Light: 0.25-0.5mg Common: 0.5-1.5mg Strong: 1.5-2mg Heavy: 2-3mg | NOTE: Higher doses increase the chances of blacking out. 1mg Delorazepam is approximately equal to 10mg Diazepam.", - "onset": "30-60 minutes.", - "after-effects": "72 hours", - "duration": "12-16 hours", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "aliases": [ - "nordiclazepam" - ] - }, - "pretty_name": "Delorazepam", - "aliases": [ - "nordiclazepam" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.25-0.5mg", - "Common": "0.5-1.5mg", - "Strong": "1.5-2mg", - "Heavy": "2-3mg" - } - }, - "formatted_duration": { - "value": "12-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "72", - "_unit": "hours" - }, - "dose_note": " NOTE: Higher doses increase the chances of blacking out. 1mg Delorazepam is approximately equal to 10mg Diazepam.", - "id": 322 - }, - "tilidine": { - "name": "tilidine", - "properties": { - "summary": "Synthetic opioid, used mainly for treatment of moderate to severe pain. In some countries it's mixed with Naloxone to lower the abuse liability. Though in some only Tilidine. Roughly 0.2 - 1 on the potency scale to Morphine. (So 20mg's of Morphine to 100mg's Tilidine)", - "onset": "10-20 minutes.", - "duration": "3-6 hours.", - "avoid": "All other CNS depressants.", - "dose": "Tilidine dose Oral Light: 25-50mg Common: 50-100mg Strong: 100-200mg.", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "aliases": [ - "tilidate", - "tilidin", - "valoron", - "valtran" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Tilidine", - "aliases": [ - "tilidate", - "tilidin", - "valoron", - "valtran" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Tilidine": { - "Light": "25-50mg", - "Common": "50-100mg", - "Strong": "100-200mg." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-20", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 323 - }, - "u-51754": { - "name": "u-51754", - "properties": { - "summary": "A very potent opioid, that seems to have a fair bit of κ-opioid action. So Dyshopria, Auditory hallucinations can be an effect. Is an analogue of U-47700.", - "onset": "Oral: 15-30 minutes. | Insufflated: 5-10 minutes. | Plugged: 5-10 minutes.", - "duration": "Oral: 2-4 hours. | Insufflated: 1-2 hours. | Plugged: 1-2 hours.", - "categories": [ - "tentative", - "opioid", - "dissociative", - "depressant", - "research-chemical" - ], - "aliases": [ - "methene-u47700", - "methene-u-47700" - ], - "after-effects": "3-6 hours.", - "dose": "Rectal Light: 1-3mg Common: 3-5mg Strong: 5-10mg" - }, - "pretty_name": "U-51754", - "aliases": [ - "methene-u47700", - "methene-u-47700" - ], - "categories": [ - "tentative", - "opioid", - "dissociative", - "depressant", - "research-chemical" - ], - "formatted_dose": { - "Rectal": { - "Light": "1-3mg", - "Common": "3-5mg", - "Strong": "5-10mg" - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "1-2", - "Plugged": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-10", - "Plugged": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "3-6", - "_unit": "hours" - }, - "id": 324 - }, - "crl-40-940": { - "name": "crl-40-940", - "properties": { - "summary": "Bisfluoro analogue Modafinil. Has been sold online as a research chemical. Was patented in 2013. Is slightly more potent than Armodafinil.", - "aliases": [ - "flmodafinil", - "lauflumide", - "bisfluoromodafinil" - ], - "dose": "Light: 20-40mg Common: 40-75mg Strong: 75-150mg.", - "onset": "30-45 minutes.", - "duration": "6-12 hours.", - "categories": [ - "stimulant", - "tentative", - "nootropic", - "research-chemical" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "CRL-40-940", - "aliases": [ - "flmodafinil", - "lauflumide", - "bisfluoromodafinil" - ], - "categories": [ - "stimulant", - "tentative", - "nootropic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "20-40mg", - "Common": "40-75mg", - "Strong": "75-150mg." - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 325 - }, - "noopept": { - "name": "noopept", - "properties": { - "summary": "A common nootropic often attributed with temporarily increasing intelligence, concentration, focus and memory recall. Daily use can lead to dependency with withdrawals which make the user feel 'stupid.' Often taken daily in a 'stack' with other nootropics.", - "onset": "Oral: 15-30 minutes | Sublingual: 5-10 minutes | Intranasal: 0-5 minutes.", - "duration": "3-6 hours depending on stomach contents/ROA/ect.", - "dose": "Oral Light: 5mg Common: 10mg Strong: 10-20mg+ | Sublingual/Insufflated Light: 2-5mg Common: 5-10mg Strong: 10mg+", - "avoid": "Because Noopept modulates AMPA and NMDA receptors dissociative drugs like Ketamine, MXE,etc. will have diminished effects with Noopept. It can also have unpredictable potentiating effects on Psychedelics, Alcohol, Cannabis and some Stimulants. Use caution when combining with drugs.", - "categories": [ - "research-chemical", - "nootropic" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Noopept", - "categories": [ - "research-chemical", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Light": "5mg", - "Common": "10mg", - "Strong": "10-20mg+" - }, - "Sublingual/Insufflated": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Sublingual": "5-10", - "Intranasal": "0-5", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Noopept_.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Rejuvenation": "https://psychonautwiki.org/wiki/Rejuvenation", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 326 - }, - "fluvoxamine": { - "name": "fluvoxamine", - "properties": { - "categories": [ - "ssri" - ], - "aliases": [ - "luvox", - "faverin" - ] - }, - "pretty_name": "Fluvoxamine", - "aliases": [ - "luvox", - "faverin" - ], - "categories": [ - "ssri" - ], - "id": 327 - }, - "metaxalone": { - "name": "metaxalone", - "properties": { - "dose": "Oral Light: 400-800mg. Common: 800-1600mg. Strong: 1600-2400mg.", - "onset": "15-45 minutes.", - "duration": "4-8 hours.", - "summary": "Muscle relaxant, that is used to relieve pain from general pain, and other musculoskeletal conditions.", - "aliases": [ - "skelaxin" - ], - "categories": [ - "depressant" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Metaxalone", - "aliases": [ - "skelaxin" - ], - "categories": [ - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "400-800mg.", - "Common": "800-1600mg.", - "Strong": "1600-2400mg." - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Metaxalone.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 328 - }, - "4-emc": { - "name": "4-emc", - "properties": { - "summary": "A stimulant that is a structural isomer of 4-MEC.", - "aliases": [ - "4-ethylmethcathinone" - ], - "onset": "20-60 minutes.", - "duration": "3-5 hours", - "after-effects": "2-8 hours.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "dose": "Light: 50-100mg Common: 100-200mg Strong: 200mg+" - }, - "pretty_name": "4-EMC", - "aliases": [ - "4-ethylmethcathinone" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-200mg", - "Strong": "200mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4Ethylmethcathinone.shtml" - }, - "formatted_aftereffects": { - "value": "2-8", - "_unit": "hours" - }, - "id": 329 - }, - "clobazam": { - "name": "clobazam", - "properties": { - "Summary": "A long acting half life benzo that focues on Anxiolytic and/or Anticonvulsant.", - "dose": "Light: 5-10mg Common: 10-15mg Heavy: 15-30mg+ | NOTE: 20mg of Clobazam is approximately equal to 10mg of Diazepam", - "onset": "20-40 minutes", - "duration": "6-12 hours.", - "avoid": "All other CNS depressants", - "aliases": [ - "frisium" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "summary": "A long acting benzodiazepine which focuses primarily on anxiolytic and anticonvulsant properties. It is used medically to treat epilepsy, and this along with its relatively many negative side-effects and contraindications in comparison with other benzodiazepines means it isn't frequently used recreationally.", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia.", - "bioavailability": "Oral 85-90%", - "after-effects": "1-12 hours.", - "dose_to_diazepam": "Clobazam - 20mg ~=10mg Diazepam." - }, - "pretty_name": "Clobazam", - "aliases": [ - "frisium" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Light:": { - "Light": "5-10mg", - "Common": "10-15mg", - "Heavy": "15-30mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: 20mg of Clobazam is approximately equal to 10mg of Diazepam", - "sources": { - "_general": [ - "clobazam dosage equivalence to diazepam being 2:1 - The royal society of medicine International Congress and Symposium Series number 43: Clobazam ( Z. subhan study)", - "Clobazam at doses under 40mg is found to not significantly alter memory or learning tasks compared to placebo as opposed to diazepam which had strong negative effects on memory and learning tasks in a comparitive study done by Z. Subhan found in: The royal society of medicine International Congress and Symposium Series no. 43" - ] - }, - "id": 330 - }, - "4-fea": { - "name": "4-fea", - "properties": { - "summary": "Stimulant that is the ethyl analogue of 4-FMA.", - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ], - "aliases": [ - "4-fluoroethylamphetamine" - ], - "duration": "4-6 hours.", - "dose": "Light: 25-50mg Common: 50-75mg Strong: 75-150mg+ | Note: Tentative data as of writing.", - "onset": "40-60 minutes.", - "after-effects": "1-12 hours." - }, - "pretty_name": "4-FEA", - "aliases": [ - "4-fluoroethylamphetamine" - ], - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Light:": { - "Light": "25-50mg", - "Common": "50-75mg", - "Strong": "75-150mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "40-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " Note: Tentative data as of writing.", - "id": 331 - }, - "clonidine": { - "name": "clonidine", - "properties": { - "summary": "Is a medication that is used to treat high blood pressure, anxiety, withdrawal (Typically from Alcohol, Opioids, Smoking) and many other uses.", - "dose": "Oral Light: 25-50ug Common: 50-100ug Strong: 100-250ug.", - "onset": "15-45 minutes.", - "duration": "8-16 hours.", - "avoid": "All CNS depressants.", - "categories": [ - "depressant", - "common" - ], - "aliases": [ - "catapres", - "kapvay", - "duraclon" - ], - "after-effects": "1-4 hours." - }, - "pretty_name": "Clonidine", - "aliases": [ - "catapres", - "kapvay", - "duraclon" - ], - "categories": [ - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50ug", - "Common": "50-100ug", - "Strong": "100-250ug." - } - }, - "formatted_duration": { - "value": "8-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Effect of magnesium chloride on psychomotor activity, emotional status, and acute behavioural responses to clonidine, d-amphetamine, arecoline, nic.. - https://www.ncbi.nlm.nih.gov/pubmed/21535917" - ] - }, - "id": 332 - }, - "cloniprazepam": { - "name": "cloniprazepam", - "properties": { - "onset": "15-45 minutes.", - "duration": "6-9 hours.", - "avoid": "All other CNS depressants.", - "dose": "Oral Light: .5-1mg Common: 1-2mg Strong: 2-4mg+", - "summary": "Prodrug for Clonazepam.", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming", - "tentative" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Cloniprazepam", - "categories": [ - "benzodiazepine", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": ".5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg+" - } - }, - "formatted_duration": { - "value": "6-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 333 - }, - "mk-801": { - "name": "mk-801", - "properties": { - "summary": "Dissociative research chemical similar to PCP, and Ketamine. Dizocilpine, also known as MK-801, is a non-competitive antagonist of the NMDA receptor.", - "aliases": [ - "dizocilpine", - "mk801" - ], - "dose": "Oral Common: 50-100ug", - "avoid": "Driving. Moving and walking if possible. Mixing with other depressants like alcohol, benzos and opiates.", - "duration": "20-36 hours.", - "onset": "Oral 15-30mins | IM 45mins", - "categories": [ - "dissociative", - "research-chemical", - "tentative", - "habit-forming" - ], - "after-effects": "1-72 hours." - }, - "pretty_name": "MK-801", - "aliases": [ - "dizocilpine", - "mk801" - ], - "categories": [ - "dissociative", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Common": "50-100ug" - } - }, - "formatted_duration": { - "value": "20-36", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30mins", - "IM": "45mins" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Dizocilpine.shtml" - }, - "formatted_aftereffects": { - "value": "1-72", - "_unit": "hours" - }, - "id": 334 - }, - "indapyrophenidone": { - "name": "indapyrophenidone", - "properties": { - "summary": "Indane analogue of Pyrophenidone, a NDRI stimulant with a short duration.", - "dose": "Vaporized Light: 5-10mg Common: 10-25mg Strong: 25-50mg Heavy: 50mg+. | Insufflated Light: 20-40mg Common: 40-60mg Strong: 60-90mg Heavy: 90mg+", - "duration": "Vaporized: 1-1.5 hours | Insufflated: 1-3 hours", - "categories": [ - "stimulant", - "tentative", - "research-chemical", - "habit-forming" - ], - "smmary": "Rare or new pyrovalerone drug also known as Thymergix and Centroton, with effectively no history of human use. Likely to have a similar effect profile to MDPV.", - "after-effects": "1-4 hours." - }, - "pretty_name": "Indapyrophenidone", - "categories": [ - "stimulant", - "tentative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Vaporized": { - "Light": "5-10mg", - "Common": "10-25mg", - "Strong": "25-50mg", - "Heavy": "50mg+." - }, - "Insufflated": { - "Light": "20-40mg", - "Common": "40-60mg", - "Strong": "60-90mg", - "Heavy": "90mg+" - } - }, - "formatted_duration": { - "Vaporized": "1-1.5", - "Insufflated": "1-3", - "_unit": "hours" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 335 - }, - "ghb": { - "name": "ghb", - "properties": { - "dose": "Oral Light: 0.5-1.5g Common: 1-2.5g Strong: 2-3.5g Heavy: 3.5-5g Dangerous: 7g+ | NOTE: Tends to induce heavy sedation from about the 3g mark.", - "duration": "1.5-2.5 hours", - "summary": "A euphoric depressant which is prescribed as a sleep aid and sometimes to help with Alcohol detox. Also used as a recreational depressant, as a non-toxic alternative to Alcohol. Despite not having Alcohol's toxicity it is risky due to among other things inconsistent concentration in commonly sold solution form, and can be very dangerous if taken with other depressants.", - "avoid": "Alcohol, benzos and other depressants", - "onset": "20-60 minutes", - "after-effects": "2-4 hours", - "effects": "Similar to alcohol, but subjectively 'cleaner'", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "summary=a": "euphoric depressant which is prescribed as a sleep aid and sometimes to help with Alcohol detox. Also used as a recreational depressant, as a non-toxic alternative to Alcohol. Despite not having Alcohol's toxicity it is risky due to among other things inconsistent concentration in commonly sold solution form, and can be very dangerous if taken with other depressants." - }, - "pretty_name": "GHB", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1.5g", - "Common": "1-2.5g", - "Strong": "2-3.5g", - "Heavy": "3.5-5g", - "Dangerous": "7g+" - } - }, - "formatted_duration": { - "value": "1.5-2.5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Similar to alcohol", - "but subjectively 'cleaner'" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_GHB.shtml" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "dose_note": " NOTE: Tends to induce heavy sedation from about the 3g mark.", - "sources": { - "_general": [ - "The presence of gamma-hydroxybutyric acid (GHB) and gamma-butyrolactone (GBL) in alcoholic and non-alcoholic beverages - http://www.ncbi.nlm.nih.gov/pubmed/15939164", - "Pharmacological aspects of the combined use of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) and gamma-hydroxybutyric acid (GHB): a review of t.. - http://www.ncbi.nlm.nih.gov/pubmed/16234132" - ] - }, - "id": 336 - }, - "mt-45": { - "name": "mt-45", - "properties": { - "summary": "A synthetic opioid drug that was rumoured to be roughly 80% the potency of Morphine orally. Was created by Dainippon Pharmaceutical in the 1970's. It has been used as a lead compound for the design of related substances. It has been associated with hearing loss and hair loss. Structurally unrelated to most other opioid drugs. Treat with caution, especially long term use.", - "aliases": [ - "ic-6", - "mt45" - ], - "onset": "30-45 minutes", - "duration": "4-6 hours", - "after-effects": "2-3 hours.", - "dose": "Oral Threshold: 30mg Light: 30-45mg's Common: 45-60mg Strong: 60mg+", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia." - }, - "pretty_name": "MT-45", - "aliases": [ - "ic-6", - "mt45" - ], - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Threshold": "30mg", - "Light": "30-45mg", - "Common": "45-60mg", - "Strong": "60mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MT45.shtml" - }, - "formatted_aftereffects": { - "value": "2-3", - "_unit": "hours" - }, - "id": 337 - }, - "2-ai": { - "name": "2-ai", - "properties": { - "onset": "10-30 minutes", - "summary": "Short acting stimulant that is sometimes compared to the likes of Methamphetamine. It is a rigid analogue of Amphetamine, and also partially substitutes for the prior in rat discrimination studies. ", - "duration": "1-2 hours.", - "dose": "Oral Threshold: 3-5mg Light: 5-10mg Common: 10-20mg Strong: 20-40mg+", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "half-life": "1-2 hours.", - "aliases": [ - "2ai", - "2-aminoindan" - ], - "after-effects": "2-4 hours", - "experiences": "https://www.erowid.org/experiences/subs/exp_2Aminoindan.shtml", - "test-kits": "Marquis: Orange > Brown. | Mecke: Yellow. | Mandelin: Blue. | Liebermann: Yellow Brown. | Ehrlich: No colour change." - }, - "pretty_name": "2-AI", - "aliases": [ - "2ai", - "2-aminoindan" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3-5mg", - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg+" - } - }, - "formatted_duration": { - "value": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2Aminoindan.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temporary erectile dysfunction": "https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 338 - }, - "βh-2c-b": { - "name": "βh-2c-b", - "properties": { - "summary": "β-Hydroxy-2C-B is a novel analogue of 2C-B that is a bit less potent and has a longer duration. It's thought to be the active metabolite of βk-2C-B.", - "onset": "30-50 minutes", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "aliases": [ - "beta-hydroxy-2c-b", - "bh-2c-b", - "bh-2cb", - "bohb", - "boh-2c-b", - "boh-2cb" - ], - "dose": "Light: 25-40mg Common: 40-60mg Strong: 60-75mg Heavy: 75mg+", - "duration": "7-10 hours", - "after-effects": "1-12 hours." - }, - "pretty_name": "βH-2C-B", - "aliases": [ - "beta-hydroxy-2c-b", - "bh-2c-b", - "bh-2cb", - "bohb", - "boh-2c-b", - "boh-2cb" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "25-40mg", - "Common": "40-60mg", - "Strong": "60-75mg", - "Heavy": "75mg+" - } - }, - "formatted_duration": { - "value": "7-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-50", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 339 - }, - "2-pa": { - "name": "2-pa", - "properties": { - "summary": "Amphetamine with the alpha-methyl replaced by ketone. Very few reports. Also no information on the safety of this compound. As always treat with caution.", - "duration": "3-5 hours.", - "dose": "Oral Light: 10-25mg Common: 25-50mg Strong: 50-100mg Heavy: 100+mg.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "2-phenylacetamide" - ], - "onset": "15-45 minutes.", - "after-effects": "1-10 hours." - }, - "pretty_name": "2-PA", - "aliases": [ - "2-phenylacetamide" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-100mg", - "Heavy": "100+mg." - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "id": 340 - }, - "25i-nbmd": { - "name": "25i-nbmd", - "properties": { - "summary": "A psychedelic phenethylamine that is related to the 25X-NBOMe series which in turn makes it related to the 2C-X series. Quite potent substance.", - "dose": "Sublingual Light: 800-1500ug Common: 1500-2000ug Strong: 2000-3000ug+", - "duration": "4-6 hours.", - "onset": "20-40 minutes.", - "avoid": "Other psychedelics, stimulants, and double dosing.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "25I-NBMD", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Sublingual": { - "Light": "800-1500ug", - "Common": "1500-2000ug", - "Strong": "2000-3000ug+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 341 - }, - "5-meo-pyr-t": { - "name": "5-meo-pyr-t", - "properties": { - "summary": "A very odd acting tryptamine, that is very potent. With doses as low as 3mg vapourised causing complete blocks of memory loss.", - "dose": "Oral Light: 0.5-1mg Common: 1-1.5mg Strong: 1.5-2mg's. | Vapourised Light: 0.5-1.5mg Common: 1.5-2mg Strong: 2-3mg's.", - "onset": "Oral: 5-20 minutes. | Vapourised: 1-2 minutes.", - "duration": "Oral: 2-6 hours. | Vapourised: 1-5 hours.", - "after-effects": "1-36 hours.", - "note": "Please have a tripsitter with you in person if you do indeed to consume this substance. Some may feel better the next morning and feel fine, and in some accounts, week plus until all the residual effects wore off. Be extremely cautious with this substance.", - "categories": [ - "tentative", - "research-chemical", - "psychedelic" - ] - }, - "pretty_name": "5-MeO-PYR-T", - "categories": [ - "tentative", - "research-chemical", - "psychedelic" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-1.5mg", - "Strong": "1.5-2mg" - }, - "Vapourised": { - "Light": "0.5-1.5mg", - "Common": "1.5-2mg", - "Strong": "2-3mg" - } - }, - "formatted_duration": { - "Oral": "2-6", - "Vapourised": "1-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "5-20", - "Vapourised": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-36", - "_unit": "hours" - }, - "id": 342 - }, - "nicotine": { - "name": "nicotine", - "properties": { - "summary": "A chemical found in tobacco, aubergines and tomatoes which is considered one of the most addictive drugs in existence. It is a mild stimulant, with stress relieving effects. It is widely used in the form of cigarettes, the use of which carries a high risk of causing cancer or heart issues over time. Increasingly, it is 'vaped' as a purportedly safer alternative to smoking.", - "categories": [ - "habit-forming", - "nootropic", - "common" - ] - }, - "pretty_name": "Nicotine", - "categories": [ - "habit-forming", - "nootropic", - "common" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Nicotine.shtml" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction" - }, - "sources": { - "_general": [ - "Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. -https://www.ncbi.nlm.nih.gov/pubmed/22232050", - "Nicotine treatment of mild cognitive impairment: a 6-month double-blind pilot clinical trial. - https://www.ncbi.nlm.nih.gov/pubmed/22232050", - "Site of nicotine absorption from a vapour inhaler--comparison with cigarette smoking - http://www.ncbi.nlm.nih.gov/pubmed/10663452", - "Brand differences of free-base nicotine delivery in cigarette smoke: the view of the tobacco industry documents - http://www.ncbi.nlm.nih.gov/pubmed/16728749", - "Exposure to nicotine produces an increase in dopamine D2(High) receptors: a possible mechanism for dopamine hypersensitivity. - http://www.ncbi.nlm.nih.gov/pubmed/20942582", - "Tobacco leaf, smoke and smoking, MAO inhibitors, Parkinson's disease and neuroprotection are there links? - http://www.ncbi.nlm.nih.gov/pubmed/14697903", - "Brand differences of free-base nicotine delivery in cigarette smoke: the view of the tobacco industry documents. - http://www.ncbi.nlm.nih.gov/pubmed/16728749", - "Do electronic cigarettes impart a lower potential disease burden than conventional tobacco cigarettes? Review on E-cigarette vapor versus tobacco s... - http://www.ncbi.nlm.nih.gov/pubmed/25302452", - "The impact of caffeine use on tobacco cessation and withdrawal. - http://www.ncbi.nlm.nih.gov/pubmed/9022872" - ] - }, - "id": 343 - }, - "mdoh": { - "name": "mdoh", - "properties": { - "duration": "4-6 hours", - "onset": "20-40 minutes.", - "summary": "An entactogen, stimulant and psychedelic first synthesised by Alexander Shulgin, MDOH is an analogue of MDA. Described as highly psychedelic, it is likely a serotonin releasing agent. It has not seen widespread use, perhaps due to a number of reported negative side effects such as urinary retention and a heavy comedown.", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "tentative", - "empathogen", - "habit-forming" - ], - "dose": "Threshold: 80mg Light: 100-120mg Common: 120-150mg Heavy: 150mg+ (Tentative)", - "after-effects": "1-6 hours." - }, - "pretty_name": "MDOH", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "tentative", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "80mg", - "Light": "100-120mg", - "Common": "120-150mg", - "Heavy": "150mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MDOH.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal114.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 344 - }, - "ayahuasca": { - "name": "ayahuasca", - "properties": { - "summary": "A concoction made of two or more plants that contain at least an MAOI and DMT, the combination of which allows the DMT to work orally. Typically associated to south american cultures. Also, sometimes approximated synthetically by taking an external MAOI with extracted DMT. Causes intense, spiritually orientated hallucinogenic experiences.", - "duration": "4-8 hours", - "onset": "20-60 minutes", - "avoid": "combining with any medications or substance contraindicated with MAOI's particuarly ssri's, mdxx compounds and amphetamines. Refer to http://wiki.tripsit.me/images/d/d6/TripSitDrugComboChart.gif for more info.", - "aliases": [ - "pharmahuasca", - "yage" - ], - "categories": [ - "psychedelic", - "empathogen" - ], - "after-effects": "1-8 hours", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Ayahuasca", - "aliases": [ - "pharmahuasca", - "yage" - ], - "categories": [ - "psychedelic", - "empathogen" - ], - "formatted_dose": { - "none": { - "NOTE": "Dosage" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ayahuasca.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Diarrhea": "https://psychonautwiki.org/wiki/Diarrhea", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/Exposure_to_inner_mechanics_of_consciousness", - "Feelings of eternalism": "https://psychonautwiki.org/wiki/Feelings_of_eternalism", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Feelings of self-design": "https://psychonautwiki.org/wiki/Feelings_of_self-design", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Magnification": "https://psychonautwiki.org/wiki/Magnification", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Personal meaning enhancement": "https://psychonautwiki.org/wiki/Personal_meaning_enhancement", - "Personality regression": "https://psychonautwiki.org/wiki/Personality_regression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Rejuvenation": "https://psychonautwiki.org/wiki/Rejuvenation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Thought organization": "https://psychonautwiki.org/wiki/Thought_organization" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 345 - }, - "sulbutiamine": { - "name": "sulbutiamine", - "properties": { - "summary": "A thiamine derivative nootropic and stimulant drug. Caution should be used as sulbutiamine reduces dopamine output over time with consistant usage.", - "onset": "20-40 minutes", - "duration": "6-10 hours. Dose and tolerance dependent.", - "experiences": "https://drugs-forum.com/forum/showthread.php?t=101258", - "aliases": [ - "sulbut", - "arcalion", - "enerion", - "bisibuthiamine", - "youvitan" - ], - "categories": [ - "tentative", - "stimulant", - "habit-forming", - "supplement" - ], - "dose": "Common: 200-400mg." - }, - "pretty_name": "Sulbutiamine", - "aliases": [ - "sulbut", - "arcalion", - "enerion", - "bisibuthiamine", - "youvitan" - ], - "categories": [ - "tentative", - "stimulant", - "habit-forming", - "supplement" - ], - "formatted_dose": { - "Oral": { - "Common": "200-400mg." - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "id": 346 - }, - "ephenidine": { - "name": "ephenidine", - "properties": { - "dose": "Oral Light: 50-75mg Common: 75-110mg Strong: 110-150mg Heavy: 150mg+", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "duration": "3-6 hours", - "summary": "A dissociative drug which is less potent and less confusing than MXE but with otherwise similar properties. Reported as causing light stimulant effects at lower doses.", - "onset": "10-30 minutes.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Ephenidine", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "50-75mg", - "Common": "75-110mg", - "Strong": "110-150mg", - "Heavy": "150mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ephenidine.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Ego inflation": "https://psychonautwiki.org/wiki/Ego_inflation", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 347 - }, - "nitrazolam": { - "name": "nitrazolam", - "properties": { - "summary": "Hypnotic benzodiazepine that is the triazolo analogue of Nitrazepam and about 4x more potent compared to the parent compound. Also the dechlorinated derivative of Clonazolam with roughly 1/10 potency.", - "onset": "15-30 minutes.", - "duration": "5-10 hours.", - "after-effects": "2-24 hours (Very dose dependant)", - "dose": "Oral Light: 0.5-1mg Common: 1-2mg Strong: 2-3mg+", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "tentative" - ] - }, - "pretty_name": "Nitrazolam", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-3mg+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 348 - }, - "placdyl": { - "name": "placdyl", - "properties": { - "summary": "Sedative Hypnotic medication made in the 50's. It was used for short term help for insomnia (No longer than two weeks)", - "aliases": [ - "placidyl", - "ethchlorvnol" - ], - "onset": "15-45 minutes.", - "duration": "6-9 hours", - "avoid": "All other CNS depressants", - "dose": "Oral Light: 100-200mg Common: 200-500mg Strong: 500-750mg +", - "categories": [ - "depressant", - "habit-forming" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "Ethchlorvynol", - "aliases": [ - "placidyl", - "ethchlorvnol" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "100-200mg", - "Common": "200-500mg", - "Strong": "500-750mg" - } - }, - "formatted_duration": { - "value": "6-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 349 - }, - "5-mapdb": { - "name": "5-mapdb", - "properties": { - "summary": "An entactogenic drug with similar effects to MDMA, it is related to 5-MAPB. Likely to release serotonin and show neurotoxicity in the same way as MDMA", - "duration": "5-8 hours.", - "dose": "Oral Light: 50-75mg Common: 75-120mg Strong: 120-150mg+", - "onset": "45-70 minutes.", - "after-effects": "2-4 hours. (dependant on dose)", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen" - ], - "aliases": [ - "5mapdb" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "5-MAPDB", - "aliases": [ - "5mapdb" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Light": "50-75mg", - "Common": "75-120mg", - "Strong": "120-150mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-70", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 350 - }, - "meclonazepam": { - "name": "meclonazepam", - "properties": { - "summary": "A benzodiazepine related to clonazepam discovered by Hoffman-LaRoche in the 1960s. Potentially useful in treating schistosomiasis. Has been sold on the grey market as a recreational drug but has not seen widespread popularity.", - "onset": "20-60 minutes", - "duration": "9-15 hours.", - "avoid": "All other CNS depressants.", - "dose": "Oral Light:1.50-3mg Common: 3-6mg Heavy: 6-12mg", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "tentative" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Meclonazepam", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Common": "3-6mg", - "Heavy": "6-12mg" - } - }, - "formatted_duration": { - "value": "9-15", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 351 - }, - "nordazepam": { - "name": "nordazepam", - "properties": { - "dose_to_diazepam": "Nordazepam - 10mg ~=10mg Diazepam.", - "summary": "Has all the normal benzodiazepine effects. Such as being an anti-convulsant, muscle relaxant, sedative effects, and anxiolytic. Active metabolite of Diazepam, Chlordiazepoxide, Clorazepate, among many others, which is where most of its effects come from. Has one of the longest lasting half-lifes in the class.", - "onset": "45-120 minutes.", - "duration": "10-20 hours.", - "after-effects": "1-120 hours.", - "dose": "Light: 2.5-5mg Common: 5-15mg Strong: 15-30mg+", - "aliases": [ - "nordaz", - "nordiazepam", - "desmethyldiazepam" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "avoid": "All other CNS depressants." - }, - "pretty_name": "Nordazepam", - "aliases": [ - "nordaz", - "nordiazepam", - "desmethyldiazepam" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-15mg", - "Strong": "15-30mg+" - } - }, - "formatted_duration": { - "value": "10-20", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-120", - "_unit": "hours" - }, - "id": 352 - }, - "2c-g": { - "name": "2c-g", - "properties": { - "summary": "Extremely rare drug of the 2C-X family. An extremely long lasting substance. Is nearly as potent as its amphetamine counter-part, Ganesha. Yet is said to have very little visual activity.", - "onset": "30-120 minutes.", - "duration": "15-35 hours (greatly dependant on dose)", - "dose": "Light: 20-25mg Common: 25-30mg Strong: 30mg+", - "warning": "Note this is a very long lasting compound that can be very hard on the body.", - "aliases": [ - "2cg" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-72 hours." - }, - "pretty_name": "2C-G", - "aliases": [ - "2cg" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "20-25mg", - "Common": "25-30mg", - "Strong": "30mg+" - } - }, - "formatted_duration": { - "value": "15-35", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-72", - "_unit": "hours" - }, - "id": 353 - }, - "db-mdbp": { - "name": "db-mdbp", - "properties": { - "summary": "Inactive.", - "categories": [ - "inactive" - ] - }, - "pretty_name": "DB-MDBP", - "categories": [ - "inactive" - ], - "id": 354 - }, - "bod": { - "name": "bod", - "properties": { - "summary": "Beta-methoxy analogue of 2C-D, seems to be more \"mild\" than the likes of 2C-X and DOX compounds. Is 50/50 whether the body load is barely there, or overpowering the experience.", - "duration": "8-14~ hours.", - "onset": "60-120 minutes", - "after-effects": "3-6 hours.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "dose": "Threshold: 12-15mg's Light: 15-20mg Common: 20-30mg Heavy: 30-40mg+", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "BOD", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "12-15mg", - "Light": "15-20mg", - "Common": "20-30mg", - "Heavy": "30-40mg+" - } - }, - "formatted_duration": { - "value": "8-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_BOD.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal014.shtml" - }, - "formatted_aftereffects": { - "value": "3-6", - "_unit": "hours" - }, - "id": 355 - }, - "ethylcathinone": { - "name": "ethylcathinone", - "properties": { - "summary": "Ethylcathinone is a synthetic stimulant. It is similar to ecstasy in the sense that it provides euphoria, feelings of empathy and openness, and a desire to talk with others. It also carries over to some of the negative effects of ecstasy, such as insomnia, tightened jaw muscles, and grinding of the teeth.", - "dose": "Oral Threshold: 30-50mg Light: 50-80mg Common: 80-150mg Strong: 150-300mg+ | Insufflated Threshold: 5-20mg Light: 15-30mg Common: 35-70mg Strong: 75-100mg+", - "onset": "Oral: 15-60 minutes. | Insufflated: 5-15 minutes.", - "duration": "Oral: 2-5 hours | Insufflated: 1-2 hours.", - "after-effects": "Oral: 2-3 hours. | Insufflated: 30-90 minutes.", - "aliases": [ - "ethcathinone", - "e-cat", - "eth-cat" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming" - ] - }, - "pretty_name": "Ethylcathinone", - "aliases": [ - "ethcathinone", - "e-cat", - "eth-cat" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "30-50mg", - "Light": "50-80mg", - "Common": "80-150mg", - "Strong": "150-300mg+" - }, - "Insufflated": { - "Threshold": "5-20mg", - "Light": "15-30mg", - "Common": "35-70mg", - "Strong": "75-100mg+" - } - }, - "formatted_duration": { - "Oral": "2-5", - "Insufflated": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-60", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ethylcathinone.shtml" - }, - "formatted_aftereffects": { - "Oral": "2-3", - "Insufflated": "30-90", - "_unit": "hours" - }, - "id": 356 - }, - "kanna": { - "name": "kanna", - "properties": { - "summary": "A South African plant containing numerous psychoactive alkaloids, including mesembrine and mesembrenone. The first written account of the substance was in 1662. The pharmacology of these compounds is poorly understood, but they are suspected to be serotonin uptake inhibitors and potentially monoamine releasers. Said to suppress appetite, produce mild euphoria and reduce anxiety.", - "onset": "Oral: 30-90 minutes. | Smoking: 1-2 minutes. | Insufflated: 5-10 minutes.", - "duration": "Oral 180-360 minutes. | Insufflated: 60-150 minutes. | Vapourized: 90-150 minutes", - "dose": "Oral Light: 250-500mg Common: 500-1000mg Strong: 1000-2000mg | Insufflated Light: 10-20mg Common: 20-50mg Strong: 50-150mg+ | Vapourized Light: 30-50mg Common: 50-100mg Strong: 100-250mg. | Note: We recommend against insufflating this substance, it is extremely painful and damaging to the nasal cavity.", - "avoid": "Other CNS depressants.", - "categories": [ - "habit-forming", - "depressant" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Kanna", - "categories": [ - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "250-500mg", - "Common": "500-1000mg", - "Strong": "1000-2000mg" - }, - "Insufflated": { - "Light": "10-20mg", - "Common": "20-50mg", - "Strong": "50-150mg+" - }, - "Vapourized": { - "Light": "30-50mg", - "Common": "50-100mg", - "Strong": "100-250mg." - } - }, - "formatted_duration": { - "Oral": "180-360", - "Insufflated": "60-150", - "Vapourized": "90-150", - "_unit": "minutes" - }, - "formatted_onset": { - "Oral": "30-90", - "Smoking": "1-2", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " Note: We recommend against insufflating this substance, it is extremely painful and damaging to the nasal cavity.", - "id": 357 - }, - "4-methylmethylphenidate": { - "name": "4-methylmethylphenidate", - "properties": { - "summary": "A stimulant drug related to methylphenidate and also known as 4-Me-TMP, it has demonstrated lower dopamine reuptake inhibition properties and is potentially less potent. Has been subjectively described as very similar in feel to MPH.", - "duration": "Oral: 4-6 hours | Insufflated: 2-5 hours", - "dose": "Oral Light: 25-40mg Common: 40-60mg Strong: 60-90mg Heavy: 90-125mg+ | Insufflated Light: 10-20mg Common: 20-45mg Strong: 45-70mg Heavy: 70mg+", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "onset": "Oral: 15-35 minutes. | Insufflated: 5-20 minutes.", - "aliases": [ - "4-mmph", - "4-me-tmp", - "4-metmp" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness." - }, - "pretty_name": "4-Methylmethylphenidate", - "aliases": [ - "4-mmph", - "4-me-tmp", - "4-metmp" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "25-40mg", - "Common": "40-60mg", - "Strong": "60-90mg", - "Heavy": "90-125mg+" - }, - "Insufflated": { - "Light": "10-20mg", - "Common": "20-45mg", - "Strong": "45-70mg", - "Heavy": "70mg+" - } - }, - "formatted_duration": { - "Oral": "4-6", - "Insufflated": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-35", - "Insufflated": "5-20", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "id": 358 - }, - "hexen": { - "name": "hexen", - "properties": { - "summary": "A cathinone based stimulant. Hexen (aka Ethyl-Hexedrone) acts as an NDRI to produce it's effects, and as with most cathinones has a fast onset and short duration. This drug has very little history of human consumption and next to no research/data, and therefor should be treated with caution as a research chemical.", - "categories": [ - "tentative", - "stimulant", - "habit-forming", - "research-chemical" - ], - "duration": "1-4 hours", - "dose": "Threshold: 5-15mg Light: 15-25mg Common: 25-40mg Strong: 40-50mg+", - "onset": "15-30 minutes.", - "effects": "Stimulation, Dehydration, Hypertension, Tachychardia, Increased alertness, Euphoria, Bruxism, Loss of Inhibition, Increase in energy", - "after-effects": "2-6 hours.", - "avoid": "Other stimulants. 2C-X compounds. All CNS depressants. Tramadol. DXM. MXE.", - "aliases": [ - "ethyl-hexedrone", - "n-ethylhexedrone", - "hex-en", - "n-ethyl-hexedrone" - ] - }, - "pretty_name": "Hexen", - "aliases": [ - "ethyl-hexedrone", - "n-ethylhexedrone", - "hex-en", - "n-ethyl-hexedrone" - ], - "categories": [ - "tentative", - "stimulant", - "habit-forming", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-15mg", - "Light": "15-25mg", - "Common": "25-40mg", - "Strong": "40-50mg+" - } - }, - "formatted_duration": { - "value": "1-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Stimulation", - "Dehydration", - "Hypertension", - "Tachychardia", - "Increased alertness", - "Euphoria", - "Bruxism", - "Loss of Inhibition", - "Increase in energy" - ], - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "id": 359 - }, - "rti-111": { - "name": "rti-111", - "properties": { - "summary": "Stimulant of the Phenyltropane class that acts as a SNDRI. Presumably it will have a slightly slower onset and bit longer duration than its parent compound Cocaine. Yet being the Tropane analogue of 3,4-CTMP.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "aliases": [ - "dichloropane" - ], - "dose": "Oral Light: 10-15mg Common: 15-30mg Strong: 30-50mg | Insufflated Light: 5-10mg Common: 10-20mg Strong: 20-40mg. | Note, this is not nice on the nose, and the duration between Oral and Insufflated are roughly around the same length.", - "duration": "Oral: 2-4 hours. | Insufflated: 2-4 hours.", - "onset": "Oral: 10-30 minutes. | Insufflated 5-15 minutes.", - "after-effects": "1-6 hours." - }, - "pretty_name": "RTI-111", - "aliases": [ - "dichloropane" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "10-15mg", - "Common": "15-30mg", - "Strong": "30-50mg" - }, - "Insufflated": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg." - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-30", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "dose_note": " Note, this is not nice on the nose, and the duration between Oral and Insufflated are roughly around the same length.", - "id": 360 - }, - "methoxyacetyl-fentanyl": { - "name": "methoxyacetyl-fentanyl", - "properties": { - "summary": "A quite potent fentanyl analogue.", - "dose": "Light: 0.25-0.5mg Common: 0.5-1.5mg Strong: 1.5mg+", - "aliases": [ - "maf", - "desfluoroocfentanil" - ], - "duration": "Insufflated: 10-20 minutes.", - "onset": "Insufflated: 10-20 minutes.", - "after-effects": "1-4 hours.", - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "opioid" - ] - }, - "pretty_name": "METHOXYACETYL-FENTANYL", - "aliases": [ - "maf", - "desfluoroocfentanil" - ], - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "opioid" - ], - "formatted_dose": { - "Oral": { - "Light": "0.25-0.5mg", - "Common": "0.5-1.5mg", - "Strong": "1.5mg+" - } - }, - "formatted_duration": { - "Insufflated": "10-20", - "_unit": "minutes" - }, - "formatted_onset": { - "Insufflated": "10-20", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 361 - }, - "hexobarbital": { - "name": "hexobarbital", - "properties": { - "summary": "Is a barbiturate that was once used for inducing anesthesia for surgery. It has a very rapid onset, and a short duration of effects.", - "onset": "1-2 minutes.", - "duration": "30-45 minutes.", - "categories": [ - "barbiturate", - "depressant", - "habit-forming", - "tentative" - ], - "avoid": "All other CNS depressants.", - "after-effects": "1-4 hours.", - "dose": "Light: 10-15mg Common: 15-20mg Strong: 20-30mg | Note: Take this with a grain of salt maybe." - }, - "pretty_name": "Hexobarbital", - "categories": [ - "barbiturate", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Light:": { - "Light": "10-15mg", - "Common": "15-20mg", - "Strong": "20-30mg" - } - }, - "formatted_duration": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "dose_note": " Note: Take this with a grain of salt maybe.", - "id": 362 - }, - "2c-b-fly-nbome": { - "name": "2c-b-fly-nbome", - "properties": { - "dose": "Insufflated Threshold: 100-200ug | Note: More research needs to be done with this chemical. Stay safe.", - "onset": "Insufflated: 5-10 minutes.", - "aliases": [ - "2cbflynbome" - ], - "categories": [ - "tentative", - "psychedelic", - "empathogen", - "research-chemical" - ] - }, - "pretty_name": "2C-B-FLY-NBOMe", - "aliases": [ - "2cbflynbome" - ], - "categories": [ - "tentative", - "psychedelic", - "empathogen", - "research-chemical" - ], - "formatted_dose": { - "Insufflated": { - "Threshold": "100-200ug" - } - }, - "formatted_onset": { - "Insufflated": "5-10", - "_unit": "minutes" - }, - "dose_note": " Note: More research needs to be done with this chemical. Stay safe.", - "id": 363 - }, - "pentylone": { - "name": "pentylone", - "properties": { - "onset": "Oral: 20-40 minutes | Insufflated: 10 minutes", - "duration": "3-4 hours.", - "summary": "A stimulant, empathogen and substituted cathinone. It was first synthesised in the 1960s, and re-appeared on the research chemical scene in 2010. Still, very little is known about the pharmacology or effects of this compound.", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming" - ], - "aliases": [ - "4-meppp", - "bk-mbdp", - "bk-methyl-k" - ], - "dose": "Light: 10-20mg Common: 20-40mg Strong: 40-80mg+", - "after-effects": "1-6 hours." - }, - "pretty_name": "Pentylone", - "aliases": [ - "4-meppp", - "bk-mbdp", - "bk-methyl-k" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-40mg", - "Strong": "40-80mg+" - } - }, - "formatted_duration": { - "value": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-40", - "Insufflated": "10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 364 - }, - "2c-c": { - "name": "2c-c", - "properties": { - "dose": "Oral Light: 15-25mg Common: 25-35mg Strong: 35-55mg Insufflated/Plugged Light: 5-15mg Common: 15-25mg Strong: 25-30mg Heavy: 30-40mg+", - "duration": "4-8 hours", - "onset": "30-120 minutes", - "aliases": [ - "2cc" - ], - "summary": "A short-acting psychedelic research chemical of the 2c-x family. Often described as being less stimulating than the other 2c-x, and is a relatively unique psychedelic in this respect.", - "effects": "euphoria, giggling, empathy, insight, brightened color, closed/open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception of time, ego softening, nausea, sweating/chills, muscle tension, confusion, insomnia", - "categories": [ - "psychedelic", - "research-chemical" - ], - "after-effects": "1-12 hours.", - "test-kits": "Marquis: Yellow > Green Brown. | Mecke: Yellow Green > Brown. | Mandelin: Orange > Yellow. | Froehde: Yellow > Green. | Liebermann: Yellow > Black > Clear. | Simon's: Pink > Brown. | Ehrlich: No colour change." - }, - "pretty_name": "2C-C", - "aliases": [ - "2cc" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-25mg", - "Strong": "25-30mg", - "Heavy": "30-40mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "euphoria", - "giggling", - "empathy", - "insight", - "brightened color", - "closed/open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception of time", - "ego softening", - "nausea", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CC.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal022.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Machinescapes": "https://psychonautwiki.org/wiki/Machinescapes", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 365 - }, - "cinolazepam": { - "name": "cinolazepam", - "properties": { - "dose": "Light: 10-30mg Common: 30-60mg Strong: 60-120mg+", - "aliases": [ - "geroderm" - ], - "summary": "A benzodiazepine derivative drug with anxiolytic effects but mainly hypnotic effects. It is extremely effective for sleep aid but has mild euphoria compared to other benzos", - "duration": "8-12 hours", - "categories": [ - "depressant", - "habit-forming" - ], - "after-effects": "12-20 hours", - "avoid": "Caution: Do not mix with alcohol or opioids/opiates, ambien or any CNS depressants in general. The combination can prove to be fatal and also increases likelihood of blacking out if you survive", - "onset": "30-90 minutes.", - "bioavailability": "Oral 90-100%" - }, - "pretty_name": "Cinolazepam", - "aliases": [ - "geroderm" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "10-30mg", - "Common": "30-60mg", - "Strong": "60-120mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "12-20", - "_unit": "hours" - }, - "id": 366 - }, - "estazolam": { - "name": "estazolam", - "properties": { - "summary": "A rarely prescribed medium-duration prescription benzodiazepine. Mainly used as a hypnotic, it can cause amnesia and lowered inhibitions in excess.", - "aliases": [ - "prosom", - "eurodin", - "elprazolam" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "dose": "Light: 0.5-1mg Common: 1-2mg Strong: 2-4mg+", - "onset": "30-60 minutes.", - "duration": "7-12 hours.", - "after-effects": "2-24 hours.", - "avoid": "All other CNS depressants.", - "bioavailability": "Oral 93%", - "dose_to_diazepam": "Estazolam - 1-2mg's ~=10mg Diazepam." - }, - "pretty_name": "Estazolam", - "aliases": [ - "prosom", - "eurodin", - "elprazolam" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg+" - } - }, - "formatted_duration": { - "value": "7-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "2-24", - "_unit": "hours" - }, - "id": 367 - }, - "alprazolam": { - "name": "alprazolam", - "properties": { - "summary": "An extremely common benzodiazepine better known as Xanax, frequently prescribed for the treatment of anxiety and panic disorders. Alprazolam is short-lasting and primarily anxiolytic, though also possesses hypnotic properties. At high doses amnesia and loss of inhibition are common. Do not mix with other depressants.", - "aliases": [ - "xanax", - "prazolam", - "ksalol", - "niravam" - ], - "avoid": "When taken for a long period of time, abrupt discontinuation is highly unadvised. Avoid combining other depressants such as Alcohol.", - "onset": "15-40 minutes", - "dose": "Oral Light: 0.25-0.5mg Common: 0.5-1.5mg Strong: 1.5-2mg Heavy: 2mg + | NOTE: Warning - higher doses increase the chances of blacking out", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hiccups, Loss of time, Loss of motor skills.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "duration": "5-8 hours", - "after-effects": "6-24 hours", - "bioavailability": "Oral 80-90%", - "dose_to_diazepam": "Alprazolam - 0.5mg ~=10mg Diazepam." - }, - "pretty_name": "Alprazolam", - "aliases": [ - "xanax", - "prazolam", - "ksalol", - "niravam" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "0.25-0.5mg", - "Common": "0.5-1.5mg", - "Strong": "1.5-2mg", - "Heavy": "2mg" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hiccups", - "Loss of time", - "Loss of motor skills", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Seizure suppression": "https://psychonautwiki.org/wiki/Seizure_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Warning - higher doses increase the chances of blacking out", - "sources": { - "_general": [ - "Role of dopaminergic and serotonergic systems on behavioral stimulatory effects of low-dose alprazolam and lorazepam. - https://www.ncbi.nlm.nih.gov/pubmed/11226811", - "tability of alprazolam, chloroquine phosphate, cisapride, enalapril maleate, and hydralazine hydrochloride in extemporaneously compounded oral liquids. - http://www.ncbi.nlm.nih.gov/pubmed/9784772", - "Alprazolam-related deaths in Palm Beach County. -http://www.ncbi.nlm.nih.gov/pubmed/15725773", - "Alprazolam kinetics following sublingual and oral administration. - http://www.ncbi.nlm.nih.gov/pubmed/3680603", - "A fatal case of Benzodiazepine withdrawal. - https://www.ncbi.nlm.nih.gov/pubmed/19465812", - "Pregnancy category D according to the FDA with potential to do genetic damage. - http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018276s044,021434s006lbl.pdf" - ] - }, - "id": 368 - }, - "midazolam": { - "name": "midazolam", - "properties": { - "summary": "A common hypnotic, sedative and anxiolytic benzodiazepine. High doses may cause amnesia and loss of inhibitions. Unusually, it is water soluble, and commonly used as a premedication for sedation as the solubility makes it better for IV use than other benzodiazepines.", - "onset": "oral 10-40 minutes | Insufflated: 1-5 minutes | Rectal: 15-25 minutes. | IV: 0-1 minutes | IM: 10-20 minutes.", - "duration": "4-8 hours.", - "dose": "Oral Low: 5-10mg's Common: 10-15mg's Strong: 15-30mg. | Insufflated Low: 3-7mg's Common: 7-15mg Strong: 15-25mg's. | Rectal Low: 3-7mg's Common: 7-15mg's Strong:15-25mg's | Intravenous Low: 2.5-5mg's Common: 5-10mg's Strong: 10-20mg's | Intramuscular Low: 3-5mg's Common: 5-12mg's Strong: 12-25mg's.", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "bioavailability": "Oral [variable - significant first-pass metabolism] | Insufflated 55% | Intramuscular 90%", - "after-effects": "1-12 hours.", - "bioavailability:": "Oral [Highly variable] | Insufflated 55% | Intramuscular 90%", - "dose_to_diazepam": "Midazolam - 10mg ~=10mg Diazepam." - }, - "pretty_name": "Midazolam", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Low": "5-10mg", - "Common": "10-15mg", - "Strong": "15-30mg." - }, - "Insufflated": { - "Low": "3-7mg", - "Common": "7-15mg", - "Strong": "15-25mg" - }, - "Rectal": { - "Low": "3-7mg", - "Common": "7-15mg" - }, - "Intravenous": { - "Low": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-20mg" - }, - "Intramuscular": { - "Low": "3-5mg", - "Common": "5-12mg", - "Strong": "12-25mg" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "oral": "10-40", - "Insufflated": "1-5", - "Rectal": "15-25", - "IV": "0-1", - "IM": "10-20", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "sources": { - "bioavailability": [ - "https://www.openanesthesia.org/midazolam_bioavailability_versus_route/" - ] - }, - "id": 369 - }, - "lsm-775": { - "name": "lsm-775", - "properties": { - "summary": "Psychedelic of the lysergamide class, less potent by weight and produces a rather mild, dreamy and even sedating trip compared to its bigger brother LSD.", - "dose": "Light: 0.5-0.75mg Common: 0.75-1mg Strong: 1-1.5mg Heavy: 1.5+mg.", - "duration": "8-13 hours", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "onset": "25-45 minutes", - "aliases": [ - "lsm" - ], - "after-effects": "1-16 hours." - }, - "pretty_name": "LSM-775", - "aliases": [ - "lsm" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-0.75mg", - "Common": "0.75-1mg", - "Strong": "1-1.5mg", - "Heavy": "1.5+mg." - } - }, - "formatted_duration": { - "value": "8-13", - "_unit": "hours" - }, - "formatted_onset": { - "value": "25-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "id": 370 - }, - "25c-nboh": { - "name": "25c-nboh", - "properties": { - "dose": "Sublingual Threshold: 100-200ug Light: 300-600ug Common: 600-1400ug Heavy: 1400-2000ug+", - "onset": "20-40 minutes", - "summary": "A phenethylamine psychedelic and stimulant derivative of 2C-C, this compound is related and has similar effects to 25c-NBOMe. It is significantly more potent than 2C-C but less potent than 25c-NBOMe. Overdoses of NBOH compounds may cause dangerous vasoconstriction. May induce uncomfortable body load.", - "duration": "4-6 hours", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-10 hours.", - "avoid": "Other psychedelics, stimulants, and double dosing." - }, - "pretty_name": "25C-NBOH", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Sublingual": { - "Threshold": "100-200ug", - "Light": "300-600ug", - "Common": "600-1400ug", - "Heavy": "1400-2000ug+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "id": 371 - }, - "5-meo-dmt": { - "name": "5-meo-dmt", - "properties": { - "summary": "A powerful psychedelic tryptamine found in many species of plants and some toad venom, with a history of use by native South Americans spanning thousands of years. Has similar qualities to DMT and related tryptamines. Very potent. Orally active in combination with an MAOI.", - "dose": "Smoked Light: 2-5mg Common 5-10mg Strong: 10-20mg | Insufflated Light: 3-5mg Common: 5-10mg Strong: 8-15mg", - "onset": "Smoked: 0-1 minutes | Insufflated: 1-5 minutes", - "duration": "Smoked: 5-15 minutes | Insufflated: 15-45 minutes", - "aliases": [ - "5meodmt", - "toads", - "5-meo", - "5meo", - "5-medmt" - ], - "effects": "Smoked: short duration, powerful rushing of sensation, overwhelming fear, panic, experience of \"the void\", ego death", - "after-effects": "Smoked: 1-2 hours | Insufflated: 1-3 hours", - "categories": [ - "psychedelic", - "research-chemical" - ] - }, - "pretty_name": "5-MeO-DMT", - "aliases": [ - "5meodmt", - "toads", - "5-meo", - "5meo", - "5-medmt" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Smoked": { - "Light": "2-5mg", - "Strong": "10-20mg" - }, - "Insufflated": { - "Light": "3-5mg", - "Common": "5-10mg", - "Strong": "8-15mg" - } - }, - "formatted_duration": { - "Smoked": "5-15", - "Insufflated": "15-45", - "_unit": "minutes" - }, - "formatted_onset": { - "Smoked": "0-1", - "Insufflated": "1-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Smoked: short duration", - "powerful rushing of sensation", - "overwhelming fear", - "panic", - "experience of \"the void\"", - "ego death" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeODMT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal38.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Bodily pressures": "https://psychonautwiki.org/wiki/Bodily_pressures", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Perception of increased weight": "https://psychonautwiki.org/wiki/Perception_of_increased_weight", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Recursion": "https://psychonautwiki.org/wiki/Recursion", - "Skin flushing": "https://psychonautwiki.org/wiki/Skin_flushing", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "Smoked": "1-2", - "Insufflated": "1-3", - "_unit": "hours" - }, - "id": 372 - }, - "aminotadalafil": { - "name": "aminotadalafil", - "properties": { - "summary": "An analogue of tadafinil, better known as Cialis (Viagra). Infamous for being missold in the 'Alpha Male' sexual enhancement supplement.", - "dose": "Light: 5-10mg Common: 10-20mg Strong: 20-30mg", - "duration": "4-8 hours." - }, - "pretty_name": "Aminotadalafil", - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-30mg" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "id": 373 - }, - "troparil": { - "name": "troparil", - "properties": { - "summary": "A stimulant and dopamine reuptake inhibitor developed in the 1970s, it is frequently used in scientific research but has seen little usage outside of the lab. Similar effects to cocaine, though much longer and without any local anaesthetic action. Probably hard on the nose.", - "dose": "Low: 15-20mg Common: 20-30mg Strong: 30-60mg+", - "onset": "<10 minutes.", - "duration": "45-70 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "after-effects": "1-2 hours." - }, - "pretty_name": "Troparil", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Low": "15-20mg", - "Common": "20-30mg", - "Strong": "30-60mg+" - } - }, - "formatted_duration": { - "value": "45-70", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "id": 374 - }, - "allobarbital": { - "name": "allobarbital", - "properties": { - "summary": "Is a barbiturate that was first made in 1912. It was primilary used as an anticonvulsant. Yet it has pretty much been outclassed by a newer generation of safer ones. Still in use in Poland.", - "duration": "6-10 hours.", - "onset": "15-30 minutes.", - "categories": [ - "barbiturate", - "tentative", - "depressant", - "habit-forming" - ], - "avoid": "All other CNS depressants.", - "dose": "Light: 500-1000mg Common: 1000-1500mg Strong: 1500-2000mg+", - "after-effects": "1-12 hours" - }, - "pretty_name": "Allobarbital", - "categories": [ - "barbiturate", - "tentative", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "500-1000mg", - "Common": "1000-1500mg", - "Strong": "1500-2000mg+" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 375 - }, - "g-130": { - "name": "g-130", - "properties": { - "summary": "Stimulant that is related to Phenmetrazine. Nearly no information on dose or effects.", - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "G-130", - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ], - "id": 376 - }, - "cyclizine": { - "name": "cyclizine", - "properties": { - "summary": "First generation antihistamine and anticholinergic drug used to combat nausea and vomiting. Causes drowsiness. Like most antihistamines in high doses it induces delirium and vivid realistic hallucinations. Probably uncomfortable and not enjoyable.", - "side-effects": "drowsiness, dry mouth, headache, psychomotor impairment, urinary retention, blurred vision, dermatitis, and gastrointestinal disturbances", - "onset": "10-30 minutes.", - "duration": "Oral 4-8 hours.", - "after-effects": "14 - 16 hours", - "dose": "Common: 25-50mg's.", - "chemistry": "IUPAC: 1-benzhydryl-4-methyl-piperazine | Formula: C18H22N2 | Molecular Mass: 266.381 g/mol | Water Solubility: 1000 mg/L (25 °C)", - "pharmacodynamics": "H1 receptor inverse agonist; mACh receptor antagonist", - "categories": [ - "depressant" - ] - }, - "pretty_name": "Cyclizine", - "categories": [ - "depressant" - ], - "formatted_dose": { - "Oral": { - "Common": "25-50mg" - } - }, - "formatted_duration": { - "value": "Oral", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Side-effects: drowsiness", - "dry mouth", - "headache", - "psychomotor impairment", - "urinary retention", - "blurred vision", - "dermatitis", - "and gastrointestinal disturbances" - ], - "formatted_aftereffects": { - "value": "14", - "_unit": "hours" - }, - "dose_note": " NOTE: The provided dosages are intended for therapeutic use.", - "id": 377 - }, - "w-15": { - "name": "w-15", - "properties": { - "summary": "A potent opioid that is 5.4x more potent than Morphine. Has a distinct structure unrelated to nearly all other opioid compounds.", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "onset": "15-40 minutes.", - "dose": "Light: 2-5mg Common: 5-10mg Strong: 10-15mg+", - "duration": "4-6 hours.", - "avoid": "All other CNS depressants.", - "after-effects": "2-4 hours." - }, - "pretty_name": "W-15", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10-15mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 378 - }, - "2c-b-an": { - "name": "2c-b-an", - "properties": { - "summary": "2C-B-AN is a novel prodrug for 2C-B.", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "dose": "Oral Light: 30-45mg Common: 45-70mg Strong: 70-100mg Heavy: 100+mg", - "duration": "5-9 hours", - "onset": "40-75 minutes", - "after-effects": "1-6 hours." - }, - "pretty_name": "2C-B-AN", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "30-45mg", - "Common": "45-70mg", - "Strong": "70-100mg", - "Heavy": "100+mg" - } - }, - "formatted_duration": { - "value": "5-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "40-75", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 379 - }, - "25t-2-nbome": { - "name": "25t-2-nbome", - "properties": { - "dose": "Sublingual Light: 100-300ug Common: 300-600ug Strong: 600-1000ug.", - "duration": "6-10 hours.", - "after-effects": "2-10 hours.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "onset": "30-45 minutes.", - "summary": "A potent serotonin receptor agonist at the 5-HT2a receptor that is of the NBOMe drug class. It is a hallucinogenic and psychedelic with limited recorded human use.", - "aliases": [ - "25t2-nbome" - ] - }, - "pretty_name": "25T-2-NBOMe", - "aliases": [ - "25t2-nbome" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Sublingual": { - "Light": "100-300ug", - "Common": "300-600ug", - "Strong": "600-1000ug." - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-10", - "_unit": "hours" - }, - "id": 380 - }, - "bk-2c-b": { - "name": "bk-2c-b", - "properties": { - "dose": "Oral Threshold: 50-60mg Common: 80-100mg Strong: 100-150mg Heavy: 150mg+", - "onset": "20-70 minutes.", - "duration": "8-12 hours.", - "aliases": [ - "bk-2cb", - "bk-2-cb", - "b-k-2cb", - "b-k2cb", - "b-k2-cb", - "b-k2-c-b", - "b-k-2-c-b", - "bk2cb" - ], - "summary": "A long-acting psychedelic and empathogen with unpredictable effectiveness. Roughly double the duration of 2c-b. Inactivated by high pH.", - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "βk-2C-B", - "aliases": [ - "bk-2cb", - "bk-2-cb", - "b-k-2cb", - "b-k2cb", - "b-k2-cb", - "b-k2-c-b", - "b-k-2-c-b", - "bk2cb" - ], - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "formatted_dose": { - "Oral": { - "Threshold": "50-60mg", - "Common": "80-100mg", - "Strong": "100-150mg", - "Heavy": "150mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-70", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_BK2CB.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 381 - }, - "pst": { - "name": "pst", - "properties": { - "summary": "Poppy Tea can be made from poppy pods, stalks and seeds, and contains various opium alkaloids including primarily Morphine, as well as Codeine and others. There is great variation in Poppy Tea potency and therefor doses are indicated for opioid naive users.", - "onset": "30-90 minutes.", - "duration": "Oral: 8-24 hours. | Note: Higher doses, usually will last around 18-24 hours. Yet, on the other side, lower doses last a fair bit shorter.", - "avoid": "All other CNS depressants.", - "aliases": [ - "poppy-seed-tea", - "poppy-tea" - ], - "note": "The doses of this are very inconsistent. Use with caution.", - "categories": [ - "opioid", - "depressant", - "habit-forming" - ], - "after-effects": "1-30 hours." - }, - "pretty_name": "PST", - "aliases": [ - "poppy-seed-tea", - "poppy-tea" - ], - "categories": [ - "opioid", - "depressant", - "habit-forming" - ], - "formatted_duration": { - "Oral": "8-24", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-30", - "_unit": "hours" - }, - "id": 382 - }, - "carisoprodol": { - "name": "carisoprodol", - "properties": { - "summary": "A skeletal muscle relaxant drug also known as Soma, carisoprodol has limited recreational value, however its main metabolite meprobamate has some moderate tranquilising properties. Sometimes found in concoctions with codeine or caffeine.", - "aliases": [ - "soma" - ], - "onset": "15-30 minutes", - "duration": "2-4 hours", - "dose": "Oral Threshold: 100mg's Light: 100-325mg's Common: 325-500mg's Strong: 500-750mg's | NOTE: Tolerance raises very fast", - "categories": [ - "depressant", - "habit-forming" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-3 hours." - }, - "pretty_name": "Carisoprodol", - "aliases": [ - "soma" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "100mg", - "Light": "100-325mg", - "Common": "325-500mg", - "Strong": "500-750mg" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-3", - "_unit": "hours" - }, - "dose_note": " NOTE: Tolerance raises very fast", - "id": 383 - }, - "2c-t": { - "name": "2c-t", - "properties": { - "summary": "A very rare psychedelic phenylethylamine, that is quite lovely.", - "dose": "Light: 50-60mg Common: 60-90mg Strong: 90-120mg", - "onset": "25-60 minutes.", - "duration": "2-6 hours.", - "categories": [ - "psychedelic", - "empathogen", - "research-chemical", - "tentative" - ], - "aliases": [ - "2ct" - ], - "after-effects": "1-4 hours." - }, - "pretty_name": "2C-T", - "aliases": [ - "2ct" - ], - "categories": [ - "psychedelic", - "empathogen", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "50-60mg", - "Common": "60-90mg", - "Strong": "90-120mg" - } - }, - "formatted_duration": { - "value": "2-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "25-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 384 - }, - "quetiapine": { - "name": "quetiapine", - "properties": { - "summary": "An atypical antipsychotic medication under the brand name Seroquel. Also used to treat insomnia and mood swings. This drug is very sedating and can stop/slow down psychedelic drug trips. Infrequently abused.", - "after-effects": "Can last up to 24 hours after one use.", - "adverse-effects": "dizziness, fatigue, extrapyramidal symptoms, increased diastolic blood pressure, increased triglycerides, increased total cholesterol, increased appetite, constipation, dry mouth, headache, and somnolence", - "drug-contradictions": "apomorphine, bromocriptine, cabergoline, carbamazepine, cimetidine, clarithromycin, dabrafenib, dopamine, erythromycin, idelalisib, itraconazole, ivacaftor, ketoconazole, levodopa, lisuride, mefloquine, methyldopa, nefazodone, ondansetron, panobinostat, pramipexole, rifabutin, rifampin, ropinirole, sodium oxybate, st. john's wort, vilanterol, and vemurafenib", - "overdose-symptoms": "sedation, hypotension, tachycardia, cardiac arrhythmia, coma, and death", - "pharmacology": "D1, D2, D3, and D4 receptor antagonist; 5-HT1A receptor partial agonist; 5-HT2A, 5-HT2C, and 5-HT7 receptor antagonist; α1-adrenergic and α2-adrenergic receptor antagonist; H1 receptor antagonist; mACh receptor antagonist", - "aliases": [ - "seroquel" - ], - "categories": [ - "depressant" - ], - "dose": "Oral Light: 25mg-50mg Common: 50mg-150mg Strong: 150mg-300mg Heavy: 300mg-800mg", - "effects": "sedation, dizziness, fatigue, constipation, dry mouth, headache, appetite change, increased blood pressure", - "chemistry": "IUPAC: 2-(2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy)ethanol | Formula: C21H25N3O2S | Molecular Mass: 383.5099 g/mol | Solubility in Water: 3.29 mg/mL (20 °C)", - "legal": "Australia: Prescription Only (S4) | United Kingdom: POM | United States: ?-only", - "onset": "Oral IR: 15-30 minutes. Oral XR: 30-60 minutes.", - "duration": "7-12 hours." - }, - "pretty_name": "Quetiapine", - "aliases": [ - "seroquel" - ], - "categories": [ - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "25mg-50mg", - "Common": "50mg-150mg", - "Strong": "150mg-300mg", - "Heavy": "300mg-800mg" - } - }, - "formatted_duration": { - "value": "7-12", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "IR", - "_unit": "minutes" - }, - "formatted_effects": [ - "sedation", - "dizziness", - "fatigue", - "constipation", - "dry mouth", - "headache", - "appetite change", - "increased blood pressure" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Creativity suppression": "https://psychonautwiki.org/wiki/Creativity_suppression", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "Can", - "_unit": "hours" - }, - "id": 385 - }, - "met": { - "name": "met", - "properties": { - "summary": "A rare psychedelic tryptamine, related to DMT and DET. Little information exists about the effects or pharmacology of this drug.", - "aliases": [ - "methylethyltryptamine" - ], - "onset": "Oral: 60-90 minutes. | Insufflated: 10-15 minutes. | Smoked: 5-10 minutes.", - "duration": "Oral: 4-6 hours. | Insufflated: 2-3 hours. | Smoked: 0.5-1 hours.", - "dose": "Oral Light: 60-80mg Common: 80-120mg Strong: 120mg+ Insufflated Light: 10-15mg Common: 15-20mg Strong: 20-25mg+ Vaporized Light: 10-20mg Common: 20-25mg Strong: 25-30mg+", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-6 hours." - }, - "pretty_name": "MET", - "aliases": [ - "methylethyltryptamine" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-25mg", - "Strong": "25-30mg+" - } - }, - "formatted_duration": { - "Oral": "4-6", - "Insufflated": "2-3", - "Smoked": "0.5-1", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "60-90", - "Insufflated": "10-15", - "Smoked": "5-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MET.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 386 - }, - "desmethylflunitrazepam": { - "name": "desmethylflunitrazepam", - "properties": { - "summary": "Benzodiazepine that is a metabolite of Flunitrazepam, and has been sold as a research chemical.", - "aliases": [ - "fonazepam", - "ro05-4435", - "norflunitrazepam" - ], - "duration": "5-10 hours.", - "onset": "30-60 minutes.", - "avoid": "All other CNS depressants.", - "after-effects": "2-12 hours.", - "dose": "Light: 0.5-1mg Common: 1-2mg Strong: 2-4mg+", - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming", - "research-chemical" - ] - }, - "pretty_name": "Desmethylflunitrazepam", - "aliases": [ - "fonazepam", - "ro05-4435", - "norflunitrazepam" - ], - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 387 - }, - "2c-b-fly": { - "name": "2c-b-fly", - "properties": { - "summary": "Psychedelic phenethylamine that is the dihydrodifuran analog of 2C-B.", - "dose": "Oral Light: 5-10mg Common: 10-18mg Strong: 18-25mg Heavy: 25mg+", - "categories": [ - "psychedelic", - "research-chemical" - ], - "onset": "30-90 minutes.", - "duration": "6-12 hours", - "aliases": [ - "2cb-fly", - "2cbfly" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-24 hours.", - "test-kits": "Marquis: Yellow > Brown Green. | Mecke: Yellow > Brown Green. | Mandelin: Brown." - }, - "pretty_name": "2C-B-FLY", - "aliases": [ - "2cb-fly", - "2cbfly" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-18mg", - "Strong": "18-25mg", - "Heavy": "25mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CBFly.shtml" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 388 - }, - "2-me-dmt": { - "name": "2-me-dmt", - "properties": { - "duration": "3-8 hours", - "onset": "Oral: 60-90 minutes. | Insufflated: 15-40 minutes.", - "dose": "Oral Light: 30-50mg Common: 50-75mg Strong: 75-100mg", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "summary": "Also known as 2,N,N-TMT, this drug was first synthesised by Alexander Shulgin. Described as a very mild psychedelic of similar subjective effects to other tryptamines. Reported as having an unusual and unpredictable dose curve, it is recommended to start low with this drug.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-5 hours." - }, - "pretty_name": "2-Me-DMT", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "30-50mg", - "Common": "50-75mg", - "Strong": "75-100mg" - } - }, - "formatted_duration": { - "value": "3-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "60-90", - "Insufflated": "15-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2MeDMT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal34.shtml" - }, - "formatted_aftereffects": { - "value": "1-5", - "_unit": "hours" - }, - "id": 389 - }, - "cyclo-methiodrone": { - "name": "cyclo-methiodrone", - "properties": { - "summary": "Empathogen with strong stimulant effects, very loosely related to benzylpiperidine.", - "categories": [ - "empathogen", - "stimulant", - "habit-forming", - "research-chemical", - "tentative" - ], - "dose": "Oral Light: 30-45mg Common: 45-65mg Strong: 65-90mg Heavy: 90+mg.", - "duration": "3-5 hours", - "onset": "25-45 minutes" - }, - "pretty_name": "Cyclo-Methiodrone", - "categories": [ - "empathogen", - "stimulant", - "habit-forming", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "30-45mg", - "Common": "45-65mg", - "Strong": "65-90mg", - "Heavy": "90+mg." - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "25-45", - "_unit": "minutes" - }, - "id": 390 - }, - "mda": { - "name": "mda", - "properties": { - "dose": "Oral Light: 30-40mg Common: 40-80mg Strong: 80-120mg Heavy: 120mg+", - "duration": "2-5 hours", - "onset": "20-90 minutes", - "summary": "A stimulant and empathogen. Similar to MDMA but typically produces more visuals than MDMA. Known to be more neurotoxic than MDMA, and is a minor metabolite of MDMA. Duration and onset similar to MDMA. The common Marquis reagent test cannot differentiate MDA and MDMA.", - "marquis": "Black", - "categories": [ - "psychedelic", - "stimulant", - "empathogen", - "habit-forming", - "common" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "MDA", - "categories": [ - "psychedelic", - "stimulant", - "empathogen", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "30-40mg", - "Common": "40-80mg", - "Strong": "80-120mg", - "Heavy": "120mg+" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-90", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MDA.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal100.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Synthesis of fluoro analogues of 3,4-(methylenedioxy)amphetamine (MDA) and its derivatives - http://www.ncbi.nlm.nih.gov/pubmed/17193269" - ] - }, - "id": 391 - }, - "pma": { - "name": "pma", - "properties": { - "warning": "A deadly neurotoxin found in some MDMA presses.", - "summary": "An empathogen with a slow onset and very strong serotonin release. This, combined with its lack of dopamine release, often leads users to dose more for the pleasurable effects which never come, leading to hospitalisations and deaths. Sometimes mis-sold as MDMA.", - "categories": [ - "stimulant", - "tentative" - ] - }, - "pretty_name": "PMA", - "categories": [ - "stimulant", - "tentative" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_PMA.shtml" - }, - "id": 392 - }, - "cyclobenzaprine": { - "name": "cyclobenzaprine", - "properties": { - "summary": "Muscle relaxant and CNS depressant used to relieve skeletal muscle spasms and associated pain in acute musculoskeletal conditions. Sometimes prescribed off-label for treatment of fibromyalgia or as a sleep aid. Has little recreational value alone, but may potentiate some opioids. May cause drowsiness, dry mouth and dizziness.", - "warning": "Do not mix with other CNS depressants, or within two weeks of a MAOI. ", - "onset": "15-45 minutes. ", - "duration": "6-12 hours", - "dose": "Light: 2-5mg Common: 5-10mg Strong: 10-15mg Heavy: 15mg+", - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "aliases": [ - "flexeril", - "apo-cyclobenzaprin", - "fexmid", - "novo-cycloprine" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "Cyclobenzaprine", - "aliases": [ - "flexeril", - "apo-cyclobenzaprin", - "fexmid", - "novo-cycloprine" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10-15mg", - "Heavy": "15mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 393 - }, - "propylhexedrine": { - "name": "propylhexedrine", - "properties": { - "summary": "A relatively common CNS stimulant sold over the counter in benzedrex inhalers.", - "aliases": [ - "benzedrex", - "propylhexadrine", - "hexahdromethamphetamine" - ], - "duration": "4-8 hours", - "avoid": "Other stimulants, it is known to raise heart rate much higher than what is safe.", - "dose": "Oral(Pure) Light: 10-20mg Common: 20-50mg Strong: 50mg+ | Insufflated(Pure) Light: 5-15mg Common: 15-30mg Strong: 30-50mg+ | Oral(Benzedrex) Light: 20-60mg Common: 60-125mg Strong: 125-250mg Heavy: 250mg+ | Insufflated (Benzedrex) Light: 10-30mg's Common: 30-75mg's Strong: 75-100mg+ | Note: Be aware of potency difference between pure HCl substance and cottons.", - "onset": "Oral: 5-15 minutes | Insufflated: 5-10 minutes.", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "after-effects": "1-16 hours." - }, - "pretty_name": "Propylhexedrine", - "aliases": [ - "benzedrex", - "propylhexadrine", - "hexahdromethamphetamine" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral(Pure)": { - "Light": "10-20mg", - "Common": "20-50mg", - "Strong": "50mg+" - }, - "Insufflated(Pure)": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg+" - }, - "Oral(Benzedrex)": { - "Light": "20-60mg", - "Common": "60-125mg", - "Strong": "125-250mg", - "Heavy": "250mg+" - }, - "Insufflated": { - "Light": "10-30mg", - "Common": "30-75mg", - "Strong": "75-100mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "5-15", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "dose_note": " Note: Be aware of potency difference between pure HCl substance and cottons.", - "sources": { - "_general": [ - "A drug toxicity death involving propylhexedrine and mitragynine. - https://www.ncbi.nlm.nih.gov/pubmed/21219704", - "A drug toxicity death involving propylhexedrine and mitragynine - https://www.ncbi.nlm.nih.gov/pubmed/21219704" - ] - }, - "id": 394 - }, - "5-apdb": { - "name": "5-apdb", - "properties": { - "summary": "An entactogenic amphetamine stimulant with similar structure and effects to MDMA. An analogue of MDA, it is a highly selective serotonin releaser but inhibits reuptake of serotonin (weakly), dopamine and norepinephrine.", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "onset": "20-60 minutes", - "duration": "4-8 hours", - "dose": "Oral Light: 50-75mg Common: 75-125mg Heavy: 125-200mg+", - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "5-APDB", - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-75mg", - "Common": "75-125mg", - "Heavy": "125-200mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5APDB.shtml" - }, - "id": 395 - }, - "mpa": { - "name": "mpa", - "properties": { - "summary": "An analogue of methamphetamine with effects close to amphetamine. Some users report negative side effects including stomach discomfort and sweating. Acts as a selective NDRI.", - "duration": "Oral: 4-6 hours | Insufflated 3-4 hours.", - "after-effects": "3-5 hours", - "dose": "Oral Threshold: 10mg Light: 20-40mg Common: 40-60mg Strong:60-80mg+ Insufflated Threshold: 5mg Light: 5-15mg Common: 20-40mg Strong: 40-60mg+", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "aliases": [ - "methiopropamine" - ], - "onset": "Oral: 30-60 minutes. | Insufflated: 15-30 minutes." - }, - "pretty_name": "MPA", - "aliases": [ - "methiopropamine" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5mg", - "Light": "5-15mg", - "Common": "20-40mg", - "Strong": "40-60mg+" - } - }, - "formatted_duration": { - "Oral": "4-6", - "Insufflated": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60", - "Insufflated": "15-30", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methiopropamine.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought organization": "https://psychonautwiki.org/wiki/Thought_organization", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "3-5", - "_unit": "hours" - }, - "id": 396 - }, - "2-pta": { - "name": "2-pta", - "properties": { - "summary": "4-Methylamphetamine with the alpha-methyl replaced by ketone. Very few reports. Also no information of the safety of this compound. As always treat with caution.", - "duration": "1-3 hours.", - "dose": "Oral Light: 10-20mg Common: 20-40mg Strong: 40-80mg Heavy: 80+mg.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "4-methyl-2-pa", - "2-(p-tolyl)acetamide" - ], - "onset": "10-25 minutes.", - "after-effects": "1-6 hours." - }, - "pretty_name": "2-PTA", - "aliases": [ - "4-methyl-2-pa", - "2-(p-tolyl)acetamide" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-40mg", - "Strong": "40-80mg", - "Heavy": "80+mg." - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-25", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 397 - }, - "phenobarbital": { - "name": "phenobarbital", - "properties": { - "summary": "CNS depressant that is used mostly for insomnia (In older patients) and epliepsy (in younger patients) And it a very strong narcotic, that can be taken most ways. It's used less as \"safer\" alternatives have been made (Benzodiazepines).", - "aliases": [ - "pheno", - "phenobarbitone", - "luminal" - ], - "onset": "Oral: 15-45 minutes. | Intravenous: 1-5 minutes.", - "duration": "Oral: 5-8 hours. | Intravenous: 4-6 hours.", - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "avoid": "All other CNS depressants.", - "after-effects": "1-24 hours.", - "dose": "Oral Light: 50-100mg's Common: 100-150mg's Strong: 150-300mg's+" - }, - "pretty_name": "Phenobarbital", - "aliases": [ - "pheno", - "phenobarbitone", - "luminal" - ], - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-150mg", - "Strong": "150-300mg" - } - }, - "formatted_duration": { - "Oral": "5-8", - "Intravenous": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Intravenous": "1-5", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 398 - }, - "3-fma": { - "name": "3-fma", - "properties": { - "summary": "Stimulant drug in the amphetamine family", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "aliases": [ - "3fma" - ], - "dose": "Oral Light: 5-15mg Common: 15-30mg Strong: 30-60mg+", - "onset": "20-40 minutes.", - "duration": "4-8 hours.", - "after-effects": "1-12 hours." - }, - "pretty_name": "3-FMA", - "aliases": [ - "3fma" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-60mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 399 - }, - "escaline": { - "name": "escaline", - "properties": { - "summary": "First synthesised in the 50s, this uncommon drug was reexamined by David Nichols in the 1990s. It is an analogue of mescaline which is roughly six times more potent, and is thus a powerful psychedelic phenethylamine. Subjective effects may include stimulation and hallucinations.", - "duration": "8-12 hours", - "after-effects": "3-5 hours", - "onset": "1.5-2 hours", - "categories": [ - "psychedelic", - "research-chemical" - ], - "dose": "Oral Threshold: 20-30mg Light: 30-45mg Common: 45-60mg Strong: 60mg+", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Escaline", - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "20-30mg", - "Light": "30-45mg", - "Common": "45-60mg", - "Strong": "60mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1.5-2", - "_unit": "hours" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Escaline.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "3-5", - "_unit": "hours" - }, - "id": 400 - }, - "o-desmethyltramadol": { - "name": "o-desmethyltramadol", - "properties": { - "summary": "A opioid analgesic which is the main active metabolite of Tramadol. Alone, it is a few times more potent than Tramadol and has additional affinity for δ and κ-opioid receptors. Has proven popular when sold, but these occasions have been rare due to patent rights.", - "onset": "Oral: 20-40 minutes | Insufflated: 20 minutes.", - "dose": "Oral Light: 10-25mg Common: 25-50mg Strong: 50-100mg+ | NOTE: Insufflation considered extremely painful.", - "duration": "3-6 hours", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "aliases": [ - "odt", - "o-smt", - "o-dsmt" - ], - "avoid": "All other CNS depressants.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-8 hours." - }, - "pretty_name": "O-Desmethyltramadol", - "aliases": [ - "odt", - "o-smt", - "o-dsmt" - ], - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "10-25mg", - "Common": "25-50mg", - "Strong": "50-100mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-40", - "Insufflated": "20", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " NOTE: Insufflation considered extremely painful.", - "id": 401 - }, - "5-meo-dipt": { - "name": "5-meo-dipt", - "properties": { - "aliases": [ - "foxy", - "foxy-methoxy", - "5meodipt" - ], - "summary": "5-methoxy-di isopropyl tryptamine, also known as 'foxy', a psychedelic tryptamine related to DMT, which distorts visual and audio perception. Reported to have a heavy body load at high doses, it behaves similarly to other drugs of its class.", - "dose": "Oral Threshold: 3mg Light: 5-10mg Common: 8-15mg Strong: 15-25mg+", - "onset": "20-40 minutes", - "duration": "4-8 hours", - "after-effects": "2-3 hours", - "categories": [ - "psychedelic", - "research-chemical", - "empathogen" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "5-MeO-DiPT", - "aliases": [ - "foxy", - "foxy-methoxy", - "5meodipt" - ], - "categories": [ - "psychedelic", - "research-chemical", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3mg", - "Light": "5-10mg", - "Common": "8-15mg", - "Strong": "15-25mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeODiPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal37.shtml" - }, - "formatted_aftereffects": { - "value": "2-3", - "_unit": "hours" - }, - "id": 402 - }, - "apap": { - "name": "apap", - "properties": { - "summary": "A common, over the counter, fever reducer and painkiller. It is mixed with many common opiates. Can cause liver damage and failure in higher doses. No recreational value.", - "aliases": [ - "acetaminophen", - "paracetamol", - "tylenol" - ], - "dose": "Pain-relief Common: 200-400mg | Fever Common: 300-500mg | NOTE: Maximum daily dose is 4g", - "categories": [ - "common" - ], - "onset": "60-60 minutes", - "duration": "4-6 hours", - "bioavailabity": "Oral: 70-90% | Rectal: 30-70%", - "after-effects": "1-2 hours." - }, - "pretty_name": "Paracetamol", - "aliases": [ - "acetaminophen", - "paracetamol", - "tylenol" - ], - "categories": [ - "common" - ], - "formatted_dose": { - "Pain-relief": { - "Common": "200-400mg" - }, - "Fever": { - "Common": "300-500mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Acetaminophen.shtml" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "dose_note": " NOTE: Maximum daily dose is 4g", - "sources": { - "dose": [ - "http://ceaccp.oxfordjournals.org/content/early/2013/10/10/bjaceaccp.mkt049.full" - ], - "duration": [ - "http://ceaccp.oxfordjournals.org/content/early/2013/10/10/bjaceaccp.mkt049.full" - ], - "_general": [] - }, - "id": 403 - }, - "4-fpp": { - "name": "4-fpp", - "properties": { - "summary": "A piperazine derivative that has been reported to have mild pyschedelic effects, and also empathogen qualities. It has been sold in many branded legal highs.", - "dose": "Light: 20-40mg Common: 40-80mg Strong: 80-150mg+", - "duration": "4-8 hours.", - "onset": "15-45 minutes.", - "categories": [ - "psychedelic", - "empathogen", - "tentative", - "stimulant" - ] - }, - "pretty_name": "4-FPP", - "categories": [ - "psychedelic", - "empathogen", - "tentative", - "stimulant" - ], - "formatted_dose": { - "Oral": { - "Light": "20-40mg", - "Common": "40-80mg", - "Strong": "80-150mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "id": 404 - }, - "1p-lsd": { - "name": "1p-lsd", - "properties": { - "duration": "8-12 hours", - "onset": "45-90 minutes.", - "dose": "Oral Light: 25-50ug Common: 50-125ug Strong: 125-200ug", - "summary": "An LSD analogue which appears to be slightly more potent with a shorter duration. Its effects are reported to be extremely similar to LSD, and thus far seems to be similarly safe. Released in late 2014, It has quickly become a highly popular research chemical due to its implicit legality, similarity to LSD and wide availability on the Internet.", - "after-effects": "6-24 hours", - "categories": [ - "psychedelic", - "research-chemical" - ], - "aliases": [ - "1plsd", - "1p" - ], - "test-kits": "Marquis: Slow Purple. | Mecke: Brown. | Mandelin: No colour change. | Froehde: No colour change. | Liebermann: No colour change. | Ehrlich's Reagent: No colour change. | Gallic Acid: Brown." - }, - "pretty_name": "1P-LSD", - "aliases": [ - "1plsd", - "1p" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50ug", - "Common": "50-125ug", - "Strong": "125-200ug" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_1PLSD.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depth perception distortions": "https://psychonautwiki.org/wiki/Depth_perception_distortions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Feelings of self-design": "https://psychonautwiki.org/wiki/Feelings_of_self-design", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "id": 405 - }, - "hot-2": { - "name": "hot-2", - "properties": { - "summary": "A rather rare psychedelic phenylethylamine that is the hydroxylated version and prodrug for 2C-T-2.", - "onset": "20-40 minutes", - "dose": "Threshold: 8mg Light: 10-12mg Common: 12-15mg Strong: 15-20mg+", - "duration": "5-12 hours", - "avoid": "It will have some 2C-T-2 in it unless the synth went perfectly and went in your body quite fast, thus you will most likely have some 2C-T-2 in your concoction which might hold the same MAOI properties of 2C-T-7.", - "aliases": [ - "hot2" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "HOT-2", - "aliases": [ - "hot2" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "8mg", - "Light": "10-12mg", - "Common": "12-15mg", - "Strong": "15-20mg+" - } - }, - "formatted_duration": { - "value": "5-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_HOT2.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal087.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 406 - }, - "4-aco-dipt": { - "name": "4-aco-dipt", - "properties": { - "summary": "An uncommon psychedelic tryptamine with a short history of human use, also known as Ipracetin. Possibly first synthesised by Alexander Shulgin. Some reports of heavy nausea, with effects comparable to 2c-b and mushrooms.", - "duration": "2-5 hours.", - "dose": "Oral Threshold: 3-5mg Light: 5-10mg Common: 10-20mg Strong: 20-35mg | NOTE: The freebase salt form of 4-AcO-DiPT is 10% more potent than the HCl salt form. These dosages are provided for the freebase salt", - "onset": "20-90 minutes. (Dependant on form and stomach contents)", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "4-acetoxy-dipt", - "4acodipt", - "ipracetin", - "iprocetyl", - "aces" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "4-AcO-DiPT", - "aliases": [ - "4-acetoxy-dipt", - "4acodipt", - "ipracetin", - "iprocetyl", - "aces" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3-5mg", - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-35mg" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4AcODiPT.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "dose_note": " NOTE: The freebase salt form of 4-AcO-DiPT is 10% more potent than the HCl salt form. These dosages are provided for the freebase salt", - "id": 407 - }, - "4f-php": { - "name": "4f-php", - "properties": { - "summary": "4-Fluoro analogue of a-PHP, yet seems to have less mania attachted to it. Dose is near on par.", - "dose": "Insufflated Light: 5-15mg Common: 15-30mg Strong: 30-50mg+", - "onset": "Insufflated 5-10 minutes.", - "duration": "3-6 hours.", - "after-effects": "1-24 hours.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ] - }, - "pretty_name": "4F-PHP", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Insufflated": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Insufflated", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 408 - }, - "gabapentin": { - "name": "gabapentin", - "properties": { - "summary": "An analogue of GABA also known as Neurontin, originally developed to treat epilepsy. Commonly prescribed for neuropathic pain, it also has pronounced anxiolytic effects leading to its use in treating anxiety disorders.", - "aliases": [ - "neurontin" - ], - "duration": "5-12 hours.", - "dose": "Oral Light: 300-600mg Common: 600-900mg Strong: 1200mg+", - "onset": "30-90 minutes", - "categories": [ - "depressant", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-6 hours." - }, - "pretty_name": "Gabapentin", - "aliases": [ - "neurontin" - ], - "categories": [ - "depressant", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "300-600mg", - "Common": "600-900mg", - "Strong": "1200mg+" - } - }, - "formatted_duration": { - "value": "5-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Seizure suppression": "https://psychonautwiki.org/wiki/Seizure_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 409 - }, - "2c-t-21": { - "name": "2c-t-21", - "properties": { - "onset": "15-40 minutes.", - "summary": "A rare psychedelic phenethylamine.", - "duration": "6-12 hours.", - "dose": "Threshold: 3mg Light: 3-5mg Common: 5-8mg Heavy: 8-12mg", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "avoid": "It is likely that this also has the MAO-A properties of the likes of 2c-t-7.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "2-12 hours.", - "test-kits": "Marquis: Fizzes Light Orange. | Mecke: Dark Purple. | Simon's: Greenish Blue." - }, - "pretty_name": "2C-T-21", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "3mg", - "Light": "3-5mg", - "Common": "5-8mg", - "Heavy": "8-12mg" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CT21.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal049.shtml" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 410 - }, - "acetildenafil": { - "name": "acetildenafil", - "properties": { - "dose": "Oral Light: 5-15mg's Common: 15-30mg's Strong: 30-40mg's.", - "summary": "An RC analogue of sildenafil (viagra) often missold as a hidden ingredient in many 'natural' sexual potency blends and supplements.", - "categories": [ - "research-chemical" - ], - "duration": "3-7 hours.", - "onset": "10-45 minutes." - }, - "pretty_name": "Acetildenafil", - "categories": [ - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-40mg" - } - }, - "formatted_duration": { - "value": "3-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "id": 411 - }, - "phenazepam": { - "name": "phenazepam", - "properties": { - "summary": "A very long acting, potent and subtle benzodiazepine. Infamous for the calamitous experiences it tends to produce in people dosing unknown amounts. Prescribed in certain countries for epilepsy and alcohol withdrawal.", - "dose": "Light: 0.5-1mg Common: 1-2mg Heavy: 2-4mg WARNING Blacking out is very likely past 4mg's, don't tempt this one.", - "onset": "15-60 minutes", - "duration": "18+ hours", - "after-effects": "36+ hours", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "dose_to_diazepam": "Phenazepam - ~1mg ~=10mg Diazepam." - }, - "pretty_name": "Phenazepam", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1-2mg", - "Heavy": "2-4mg" - } - }, - "formatted_duration": { - "value": "18+", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "36+", - "_unit": "hours" - }, - "id": 412 - }, - "3,6-dmpm": { - "name": "3,6-dmpm", - "properties": { - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ], - "summary": "Stimulant that is related to Phenmetrazine. Nearly no information on dose or effects." - }, - "pretty_name": "3,6-DMPM", - "categories": [ - "stimulant", - "tentative", - "research-chemical" - ], - "id": 413 - }, - "5f-pb-22": { - "name": "5f-pb-22", - "properties": { - "summary": "Synthetic cannabinoid, agonist of the cannabinoid receptors which has a strong sedating aspect. Being a synthetic cannabinoid it has a very fast onset.", - "dose": "Threshold: 1mg Light: 1-3mg Common: 3-5mg Strong: 5-8mg. | Note: As with all research chemicals, start with a low dose, and work your way up.", - "onset": "5-10 seconds.", - "duration": "60-90 minutes.", - "after-effects": "30-60 minutes.", - "categories": [ - "tentative", - "research-chemical", - "habit-forming" - ] - }, - "pretty_name": "5F-PB-22", - "categories": [ - "tentative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "1mg", - "Light": "1-3mg", - "Common": "3-5mg", - "Strong": "5-8mg." - } - }, - "formatted_duration": { - "value": "60-90", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "5-10" - }, - "formatted_aftereffects": { - "value": "30-60", - "_unit": "minutes" - }, - "dose_note": " Note: As with all research chemicals, start with a low dose, and work your way up.", - "id": 414 - }, - "temazepam": { - "name": "temazepam", - "properties": { - "dose": "Oral Light: 5-10mg's Common: 10-20mg Strong: 20-40mg+", - "summary": "Temazepam's brand name is Restoril. It is a hypnotic benzodiazepine with effects similar to clonazepam, frequently prescribed as a sleep aid. Some users report mild euphoria alongside the hypnotic effects.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "onset": "20-90 minutes", - "duration": "6-10 hours", - "after-effects": "6-12 hours", - "avoid": "All other CNS depressants.", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "bioavailability": "Oral 96%", - "dose_to_diazepam": "Temazepam - 20mg ~=10mg Diazepam.", - "aliases": [ - "restoril" - ] - }, - "pretty_name": "Temazepam", - "aliases": [ - "restoril" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg+" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "6-12", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Alcohol and benzodiazepines in fatal poisonings. - https://www.ncbi.nlm.nih.gov/pubmed/12170103" - ] - }, - "id": 415 - }, - "th-pvp": { - "name": "th-pvp", - "properties": { - "summary": "A pyrovalerone stimulant related to a-PVP and naphyrone. Very little information about effects or safety profile, virtually no evidence of human use.", - "dose": "Oral Light: 20-30mg Common: 30-50mg Strong: 50-70mg | Insufflated Light: 10-15mg Common: 15-25mg Strong: 25-35mg+ | Vapourized Light: 10-15mg Common: 15-25mg Strong: 25-35mg", - "onset": "Oral: 20-30 minutes. | Insufflated: 5-15 minutes. | Vapourized: 1-2 minutes.", - "duration": "Oral: 3-5 hours. | Insufflated: 2-3 hours. | Vapourized: 1 hour.", - "categories": [ - "tentative", - "research-chemical", - "stimulant", - "habit-forming" - ] - }, - "pretty_name": "TH-PVP", - "categories": [ - "tentative", - "research-chemical", - "stimulant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "20-30mg", - "Common": "30-50mg", - "Strong": "50-70mg" - }, - "Insufflated": { - "Light": "10-15mg", - "Common": "15-25mg", - "Strong": "25-35mg+" - }, - "Vapourized": { - "Light": "10-15mg", - "Common": "15-25mg", - "Strong": "25-35mg" - } - }, - "formatted_duration": { - "Oral": "3-5", - "Insufflated": "2-3", - "Vapourized": "1", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-30", - "Insufflated": "5-15", - "Vapourized": "1-2", - "_unit": "minutes" - }, - "id": 416 - }, - "rilmazafone": { - "name": "rilmazafone", - "properties": { - "summary": "Unique to Japan, this drug, also known as Rhythmy, is a benzodiazepine pro-drug which while inactive itself, is metabolised into the active compound in-vivo. Soluble in water.", - "onset": "30-60 minutes", - "duration": "6-8 hours. ", - "after-effects": "6-12 hours", - "dose": "Light: .5-1mg Common: 1-2mg Strong: 2-4mg+", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia.", - "aliases": [ - "rhythmy" - ] - }, - "pretty_name": "Rilmazafone", - "aliases": [ - "rhythmy" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": ".5-1mg", - "Common": "1-2mg", - "Strong": "2-4mg+" - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "" - ], - "formatted_aftereffects": { - "value": "6-12", - "_unit": "hours" - }, - "id": 417 - }, - "5-dbfpv": { - "name": "5-dbfpv", - "properties": { - "summary": "Stimulant of the cathinone class. Analogue of MDPV where the methylenedioxyphenyl group was replaced with a dihydrobenzofuran.", - "categories": [ - "tentative", - "stimulant", - "habit-forming", - "research-chemical" - ], - "dose": "Oral Threshold: 2-5mg Light: 5-15mg Common: 15-30mg Strong: 30-60mg.", - "onset": "Oral: 15-45 minutes. | Insufflated: 5-15 minutes.", - "after-effects": "4-12 hours." - }, - "pretty_name": "5-DBFPV", - "categories": [ - "tentative", - "stimulant", - "habit-forming", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "2-5mg", - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-60mg." - } - }, - "formatted_onset": { - "Oral": "15-45", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "4-12", - "_unit": "hours" - }, - "id": 418 - }, - "5-htp": { - "name": "5-htp", - "properties": { - "summary": "The precursor to serotonin. In some countries it is sold OTC as a supplement for mood stabilisation and insomnia. It is frequently used as a recovery supplement following the use of MDMA or any other drug that depletes serotonin. Do not mix this drug with anything serotonergic, as this can cause serotonin syndrome.", - "dose": "Therapeutic Common: 50-100mg | Sleep Common: 100-200mg | Recovery Common: 200-300mg | NOTE: Do not take this while on a serotonergic drug, only afterwards. Wait at least 12 hours following the last dose in the case of MDMA.", - "duration": "4-6 hours", - "onset": "30-60 minutes", - "effects": "sleep aid, antidepressant, appetite suppressant, nausea, mood stabilising", - "avoid": "Anything which interacts with serotonin. Including SSRIs, MAOIs, DXm, MDMA (during or before)", - "aliases": [ - "5htp", - "5-hydroxytryptophan", - "tryptophan", - "l-tryptophan", - "oxitriptan" - ], - "mdma": "5-HTP should only be taken at least 12 hours following an MDMA dose. Do not take it during or before MDMA - this can cause serotonin syndrome.", - "categories": [ - "common", - "supplement" - ] - }, - "pretty_name": "5-HTP", - "aliases": [ - "5htp", - "5-hydroxytryptophan", - "tryptophan", - "l-tryptophan", - "oxitriptan" - ], - "categories": [ - "common", - "supplement" - ], - "formatted_dose": { - "Therapeutic": { - "Common": "50-100mg" - }, - "Sleep": { - "Common": "100-200mg" - }, - "Recovery": { - "Common": "200-300mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "sleep aid", - "antidepressant", - "appetite suppressant", - "nausea", - "mood stabilising" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Tryptophan.shtml" - }, - "dose_note": " NOTE: Do not take this while on a serotonergic drug, only afterwards. Wait at least 12 hours following the last dose in the case of MDMA.", - "id": 419 - }, - "methedrone": { - "name": "methedrone", - "properties": { - "summary": "BK-PMMA Closely related to PMMA and others. Stimulant.", - "aliases": [ - "bk-pmma" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ] - }, - "pretty_name": "Methedrone", - "aliases": [ - "bk-pmma" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "id": 420 - }, - "huperzine-a": { - "name": "huperzine-a", - "properties": { - "summary": "A compound that is extracted from the herbs of Huperziceae family. Is known as an acetylcholinesterase inhibitor, which stops an enzyme from breaking down acetylcholine which results in increases in acetylcholine. Is currently in preliminary trials for Alzheimer's.", - "dose": "Insufflted Light: 50-75ug Common: 75-150ug Strong: 150ug-200ug. | Note: This substance is usually taken once a day, and is usually \"cycled\" off after 2-4 weeks. The optimal amount of time to break for in unknown as of yet. The doses are the same as for Oral.", - "onset": "Oral: 10-20 minutes. | Insufflated: 1-2 minutes.", - "duration": "Oral: 8-14 hours. | Insufflated: 6-12 hours.", - "aliases": [ - "h-a" - ], - "categories": [ - "nootropic", - "tentative" - ], - "after-effects": "1-14 hours.", - "avoid": "Anticholinergic drugs, which include many first generation antihistamines. Acetylcholinesterase inhibitors. Cholinergic drugs. As it may add to the negative side-effects." - }, - "pretty_name": "HUPERZINE-A", - "aliases": [ - "h-a" - ], - "categories": [ - "nootropic", - "tentative" - ], - "formatted_dose": { - "Insufflted": { - "Light": "50-75ug", - "Common": "75-150ug", - "Strong": "150ug-200ug." - } - }, - "formatted_duration": { - "Oral": "8-14", - "Insufflated": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "10-20", - "Insufflated": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-14", - "_unit": "hours" - }, - "dose_note": " Note: This substance is usually taken once a day, and is usually \"cycled\" off after 2-4 weeks. The optimal amount of time to break for in unknown as of yet. The doses are the same as for Oral.", - "id": 421 - }, - "propylphenidate": { - "name": "propylphenidate", - "properties": { - "dose": "Oral Light: 15-25mg Common: 25-60mg Strong: 60-100mg Heavy: 100mg+", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "summary": "Propylphenidate is a short acting stimulant.", - "duration": "1.5-3 hours.", - "onset": "15-25 minutes.", - "aliases": [ - "pph" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Propylphenidate", - "aliases": [ - "pph" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "15-25mg", - "Common": "25-60mg", - "Strong": "60-100mg", - "Heavy": "100mg+" - } - }, - "formatted_duration": { - "value": "1.5-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-25", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 422 - }, - "piracetam": { - "name": "piracetam", - "properties": { - "summary": "A racetam nootropic claimed by many to have cognitive benefits however this has never been strongly supported in healthy individuals. Prescribed in the UK as a treatment for myoclonus. Potentially an ampakine. One of the first popular 'nootropics.'", - "dose": "Common: 1200-4800mg | Note: Doses are normally split up to be taken 3x a day.", - "onset": "15-35 minutes.", - "categories": [ - "nootropic" - ], - "duration": "3-6 hours.", - "after-effects": "1-6 hours.", - "aliases": [ - "nootropil", - "lucetam", - "noostan", - "breinox", - "oikamid", - "geratam", - "biotropil" - ] - }, - "pretty_name": "Piracetam", - "aliases": [ - "nootropil", - "lucetam", - "noostan", - "breinox", - "oikamid", - "geratam", - "biotropil" - ], - "categories": [ - "nootropic" - ], - "formatted_dose": { - "Common:": { - "Common": "1200-4800mg" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-35", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Piracetam.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "dose_note": " Note: Doses are normally split up to be taken 3x a day.", - "id": 423 - }, - "mdpv": { - "name": "mdpv", - "properties": { - "summary": "MDPV is a potent, and extremely compulsive synthetic euphoric stimulant, which shares some empathogenic effects with MDMA. Has a reputation for causing psychosis. MDPV has been found in products sold as \"bath salts\", \"plant food/fertilizer\", and in some \"ecstasy.\"", - "dose": "Insufflated Threshold: 1-3mg Light: 2-5mg Common: 5-11mg Strong: 10-20mg | Oral Threshold: 2-6mg Light: 4-10mg Common: 8-15mg Strong: 12-25mg | Rectal Threshold: 1-5mg Light: 3-8mg Common: 6-12mg Strong: 10-25mg", - "aliases": [ - "bath_salts" - ], - "duration": "Oral: 2-7 hours | Insufflated: 2-4 hours", - "onset": "Oral: 15-30 minutes | Insufflated: 5-20 minutes", - "after-effects": "2-48 hours", - "effects": "stimulation (mental and physical), euphoria, increased mental clarity, elevated heart rate, headache, confusion, paranoia, loss of apetite, muscle tension", - "marquis": "Yellow", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ] - }, - "pretty_name": "MDPV", - "aliases": [ - "bath_salts" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Insufflated": { - "Threshold": "1-3mg", - "Light": "2-5mg", - "Common": "5-11mg", - "Strong": "10-20mg" - }, - "Oral": { - "Threshold": "2-6mg", - "Light": "4-10mg", - "Common": "8-15mg", - "Strong": "12-25mg" - }, - "Rectal": { - "Threshold": "1-5mg", - "Light": "3-8mg", - "Common": "6-12mg", - "Strong": "10-25mg" - } - }, - "formatted_duration": { - "Oral": "2-7", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-20", - "_unit": "minutes" - }, - "formatted_effects": [ - "stimulation (mental and physical)", - "euphoria", - "increased mental clarity", - "elevated heart rate", - "headache", - "confusion", - "paranoia", - "loss of apetite", - "muscle tension" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MDPV.shtml" - }, - "formatted_aftereffects": { - "value": "2-48", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Effect of synthetic cathinones: mephedrone, butylone and 3,4 methylene-dioxypyrovalerone (MDPV) on social separation induced distress vocalization,.. - http://www.ncbi.nlm.nih.gov/pubmed/25107736" - ] - }, - "id": 424 - }, - "2-mmc": { - "name": "2-mmc", - "properties": { - "summary": "A cathinone, yet the effects are noted more of the likes of 2-FA or amphetamine. Which apparently left people dissapointed.", - "dose": "Oral Light: 20-50mg Common: 50-100mg Strong: 100-135mg. | Insufflated Light: 5-15mg Common: 15-40mg Strong: 40-80mg.", - "onset": "Oral: 15-45 minutes. | Insufflated: 2-15 minutes.", - "duration": "Oral: 3-5 hours. | Insufflated: 2-4 hours.", - "after-effects": "Oral: 2-8 hours. | Insufflated: 2-4 hours.", - "categories": [ - "stimulant", - "habit-forming", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "2-MMC", - "categories": [ - "stimulant", - "habit-forming", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "20-50mg", - "Common": "50-100mg", - "Strong": "100-135mg." - }, - "Insufflated": { - "Light": "5-15mg", - "Common": "15-40mg", - "Strong": "40-80mg." - } - }, - "formatted_duration": { - "Oral": "3-5", - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Insufflated": "2-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "2-8", - "Insufflated": "2-4", - "_unit": "hours" - }, - "id": 425 - }, - "flubromazolam": { - "name": "flubromazolam", - "properties": { - "dose": "Oral Threshold: 80ug Light: 100-200ug Common: 200-400ug Strong: 400-600ug+ | NOTE: These doses are tentative and may need further research.", - "summary": "A very potent benzodiazepine derivative that is related to Triazolam and Pyrazolam. Popular in the research chemical scene, it is a potent sedative, hypnotic and anxiolytic. Potential for amnesia and reduced inhibitions in higher dose. Not to be confused with Flubromazepam, which is much less potent and has a much longer half-life.", - "onset": "20-45 minutes.", - "duration": "6-12 hours", - "after-effects": "6-24 hours", - "avoid": "All other CNS depressants.", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "aliases": [ - "f-lam", - "flam" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "dose_to_diazepam": "Flubromazolam - 0.25mg ~=10mg Diazepam." - }, - "pretty_name": "Flubromazolam", - "aliases": [ - "f-lam", - "flam" - ], - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Threshold": "80ug", - "Light": "100-200ug", - "Common": "200-400ug", - "Strong": "400-600ug+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Flubromazolam.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 426 - }, - "thiopental": { - "name": "thiopental", - "properties": { - "summary": "Barbiturate that kicks in very quickly, that is used to Anesthesia, Medical induced comas among other things.", - "onset": "Intravenous: 0-2 minutes.", - "duration": "Intravenous: 6-10 hours.", - "categories": [ - "barbiturate", - "habit-forming", - "depressant" - ], - "avoid": "All other CNS depressants.", - "after-effects": "1-24 hours." - }, - "pretty_name": "Thiopental", - "categories": [ - "barbiturate", - "habit-forming", - "depressant" - ], - "formatted_duration": { - "Intravenous": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "Intravenous": "0-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 427 - }, - "ethketamine": { - "name": "ethketamine", - "properties": { - "summary": "Ethketamine is a research chemical with properties similar to ketamine. While ketamine is a dissociative anesthetic producing hallucinogenic and sedative effects, recreational users have reported euphoria and dissociation when using NENK.", - "aliases": [ - "n-ethyl-norketamine", - "nek", - "n-ethylnorketamine" - ], - "duration": "Oral: 2-4 hours | Insufflated: 1-3 hours.", - "onset": "Oral: 15-30 minutes. | Insufflated: 5-15 minutes.", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "dose": "Light: 15-40mg Common: 40-90mg Strong: 90-160mg.", - "after-effects": "Oral: 1-3 hours. | Insufflated 1-2 hours." - }, - "pretty_name": "Ethketamine", - "aliases": [ - "n-ethyl-norketamine", - "nek", - "n-ethylnorketamine" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "15-40mg", - "Common": "40-90mg", - "Strong": "90-160mg." - } - }, - "formatted_duration": { - "Oral": "2-4", - "Insufflated": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "1-3", - "Insufflated": "1-2", - "_unit": "hours" - }, - "id": 428 - }, - "viloxazine": { - "name": "viloxazine", - "properties": { - "summary": "NRI that was used as an antidepressant in some European countries, and had a pronouced stimulant effect similar to amphetamines without any signs of dependence. Withdrawn in the early 2000s.", - "duration": "3-6 hours.", - "onset": "15-30 minutes.", - "categories": [ - "stimulant", - "tentative" - ], - "dose": "Light: 50-75mg Common: 75-150mg Strong: 150mg+" - }, - "pretty_name": "Viloxazine", - "categories": [ - "stimulant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "50-75mg", - "Common": "75-150mg", - "Strong": "150mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "id": 429 - }, - "proscaline": { - "name": "proscaline", - "properties": { - "duration": "6-12 hours.", - "onset": "30-60 minutes", - "summary": "A very uncommon psychedelic stimulant and phenethylamine and analogue on mescaline with similar effects. Roughly 5-7 times more potent than mescaline by weight.", - "dose": "Oral Threshold: 15mg's Light: 15-30mg's Common: 30-40mg's Strong: 40-60mg's", - "after-effects": "3-5 hours.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Proscaline", - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "15mg", - "Light": "15-30mg", - "Common": "30-40mg", - "Strong": "40-60mg" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "3-5", - "_unit": "hours" - }, - "id": 430 - }, - "5-meo-nipt": { - "name": "5-meo-nipt", - "properties": { - "summary": "A little known and little studied tryptamine and analogue of NiPT, also related to DiPT and DET. Psychedelic, that is generally regarded as not worth the time.", - "dose": "Threshold: 2-4mg Common: 4-8mg Common: 8-15mg Strong: 15-25mg", - "onset": "30-60 minutes.", - "duration": "4-6 hours.", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "aliases": [ - "5meonipt" - ], - "after-effects": "1-16 hours." - }, - "pretty_name": "5-MeO-NIPT", - "aliases": [ - "5meonipt" - ], - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "2-4mg", - "Common": "8-15mg", - "Strong": "15-25mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "id": 431 - }, - "mbdb": { - "name": "mbdb", - "properties": { - "summary": "A rare entactogenic drug and analogue of MDMA possibly first synthesised by David Nichols. Potentially less potent than related drugs of its type. Sometimes referred to as a 'watered down MDMA.'", - "duration": "3-8 hours", - "dose": "Light: 150-180mg Common: 180-210mg Strong: 210-250mg+", - "onset": "30-120 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "empathogen", - "habit-forming" - ], - "after-effects": "1-12 hours.", - "aliases": [ - "eden", - "methyl-j" - ] - }, - "pretty_name": "MBDB", - "aliases": [ - "eden", - "methyl-j" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "150-180mg", - "Common": "180-210mg", - "Strong": "210-250mg+" - } - }, - "formatted_duration": { - "value": "3-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MBDB.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 432 - }, - "tolibut": { - "name": "tolibut", - "properties": { - "summary": "Analogue of GABA, and the 4-methyl analogue of Phenibut. Has similar effects, acts on GABA(B).", - "categories": [ - "depressant", - "habit-forming", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "Tolibut", - "categories": [ - "depressant", - "habit-forming", - "research-chemical", - "tentative" - ], - "id": 433 - }, - "4-epd": { - "name": "4-epd", - "properties": { - "onset": "Insufflated: 10-30 minutes.", - "duration": "1-3 hours.", - "summary": "An obscure analogue of Pentedrone, which means very little information on this chemical. It is likely is shares the same general effects of the other Pentedrone family.", - "after-effects": "1-6 hours.", - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ], - "dose": "Insufflated Light: 10-20mg Common: 20-30mg Strong: 30-50mg's.", - "aliases": [ - "4-ethylpentedrone" - ] - }, - "pretty_name": "4-EPD", - "aliases": [ - "4-ethylpentedrone" - ], - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Insufflated": { - "Light": "10-20mg", - "Common": "20-30mg", - "Strong": "30-50mg" - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 434 - }, - "lsz": { - "name": "lsz", - "properties": { - "dose": "Threshold: 80ug Light: 100-150ug Common: 150-300ug Heavy: 300ug+", - "duration": "7-10 hours", - "onset": "90-120 minutes.", - "summary": "A lysergamide very similar to LSD usually distinguishable only by its shorter duration, though some subjective reports have noted it may be slightly more introspective and slightly less confusing.", - "after-effects": "1-24 hours.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "LSZ", - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "80ug", - "Light": "100-150ug", - "Common": "150-300ug", - "Heavy": "300ug+" - } - }, - "formatted_duration": { - "value": "7-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "90-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_LSZ.shtml" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 435 - }, - "aleph": { - "name": "aleph", - "properties": { - "summary": "The first sulphur-containing Phenethylamine to have been evaluated for CNS activity for Stimulant or Psychedelic purposes.", - "dose": "Oral Light: 2-4mg Common: 4-6mg Strong: 6-12mg.", - "duration": "5-10 hours.", - "onset": "30-90 minutes.", - "after-effects": "1-24 hours.", - "avoid": "All other drugs as this is a one of kind.", - "aliases": [ - "dot", - "para-dot" - ], - "categories": [ - "psychedelic", - "empathogen", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "Aleph", - "aliases": [ - "dot", - "para-dot" - ], - "categories": [ - "psychedelic", - "empathogen", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "2-4mg", - "Common": "4-6mg", - "Strong": "6-12mg." - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 436 - }, - "3-meo-pcmo": { - "name": "3-meo-pcmo", - "properties": { - "dose": "Oral Light: 50-80mg Common: 80-125mg Strong: 125-150mg+", - "duration": "3-5 hours.", - "onset": "30-60 minutes.", - "avoid": "All other CNS depressants.", - "categories": [ - "dissociative", - "research-chemical", - "tentative" - ], - "summary": "A less common dissociative anaesthetic compound related to PCP. An analogue of 3-meo-pcp, but far less potent. Possibly an antitussive and antidepressant. Very little history of human use or pharmacological information.", - "after-effects": "2-8 hours." - }, - "pretty_name": "3-MeO-PCMO", - "categories": [ - "dissociative", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "50-80mg", - "Common": "80-125mg", - "Strong": "125-150mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_3MeOPCMo.shtml" - }, - "formatted_aftereffects": { - "value": "2-8", - "_unit": "hours" - }, - "id": 437 - }, - "2-methylamphetamine": { - "name": "2-methylamphetamine", - "properties": { - "summary": "Also known as Ortetamine, this rarely seen amphetamine is approximately 1/10th as potent as dextroamphetamine. Little information exists regarding its safety or effects.", - "dose": "Insufflated Light: 10-30mg Common: 30-50mg Strong: 50-70mg+", - "duration": "Insufflated 3-6 hours.", - "onset": "Insufflated 10-30 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "2-ma" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "after-effects": "Insufflated: 1-10 hours." - }, - "pretty_name": "2-MA", - "aliases": [ - "2-ma" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Insufflated": { - "Light": "10-30mg", - "Common": "30-50mg", - "Strong": "50-70mg+" - } - }, - "formatted_duration": { - "value": "Insufflated", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Insufflated", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "Insufflated": "1-10", - "_unit": "hours" - }, - "id": 438 - }, - "doxylamine": { - "name": "doxylamine", - "properties": { - "summary": "A first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.", - "onset": "20-30 minutes", - "duration": "6-8 hours", - "dose": "Threshold: 6.25mg Common: 10-20mg Heavy: 20-50mg.", - "warning": "As with other first generation antihistamines, if you take too much you could have a delirant like experience.", - "categories": [ - "depressant", - "deliriant" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "Doxylamine", - "categories": [ - "depressant", - "deliriant" - ], - "formatted_dose": { - "Oral": { - "Threshold": "6.25mg", - "Common": "10-20mg", - "Heavy": "20-50mg." - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 439 - }, - "khat": { - "name": "khat", - "properties": { - "summary": "A shrub whose leaves contain Cathinone and Cathine, they are mostly chewed for the stimulant effect they provide. Very long history of human use.", - "onset": "Chewed: 10-15 minutes", - "duration": "30-120 minutes.", - "avoid": "Other stimulants", - "categories": [ - "habit-forming", - "stimulant" - ], - "after-effects": "1-10 hours." - }, - "pretty_name": "Khat", - "categories": [ - "habit-forming", - "stimulant" - ], - "formatted_duration": { - "value": "30-120", - "_unit": "minutes" - }, - "formatted_onset": { - "Chewed": "10-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "id": 440 - }, - "25b-nboh": { - "name": "25b-nboh", - "properties": { - "summary": "A phenethylamine psychedelic and stimulant derivative of 2C-B, this compound is related to and has similar effects to 25b-NBOMe. It is significantly more potent than 2C-B but less potent than 25B-NBOMe. Overdoses of NBOH compounds may cause dangerous vasoconstriction. May induce uncomfortable body load.", - "aliases": [ - "25bnboh", - "nboh-2cb", - "2cb-nboh", - "2c-b-nboh" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "duration": "4-10 hours.", - "onset": "20-40 minutes.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "dose": "Sublingually Light: 200-400ug Common: 400-800ug Strong: 800ug-1mg. | NOTE: Do not play around with this substance as there is very little data around.", - "after-effects": "1-12 hours.", - "avoid": "Other psychedelics, stimulants, and double dosing." - }, - "pretty_name": "25B-NBOH", - "aliases": [ - "25bnboh", - "nboh-2cb", - "2cb-nboh", - "2c-b-nboh" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Sublingually": { - "Light": "200-400ug", - "Common": "400-800ug", - "Strong": "800ug-1mg." - } - }, - "formatted_duration": { - "value": "4-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Do not play around with this substance as there is very little data around.", - "id": 441 - }, - "parafluorofentanyl": { - "name": "parafluorofentanyl", - "properties": { - "summary": "Rare, little known and extremely potent analogue of Fentanyl developed by Janssen Pharmaceutica in the 1960s. Use with extreme caution and never mix with other depressants.", - "dose": "Insufflated Light: 10-25ug Common: 25-40ug Strong: 40-65ug+", - "onset": "Oral: 5-10 minutes. | Insufflated: 0-1 minute.", - "after-effects": "Oral: 1-4 hours. | Insufflated: 1-2 hours.", - "duration": "Oral: 3-4 hours. | Insufflated: 2-3 hours.", - "aliases": [ - "pff", - "4-fluorofentanyl" - ], - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ] - }, - "pretty_name": "Parafluorofentanyl", - "aliases": [ - "pff", - "4-fluorofentanyl" - ], - "categories": [ - "opioid", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Insufflated": { - "Light": "10-25ug", - "Common": "25-40ug", - "Strong": "40-65ug+" - } - }, - "formatted_duration": { - "Oral": "3-4", - "Insufflated": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "5-10", - "Insufflated": "0-1", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "1-4", - "Insufflated": "1-2", - "_unit": "hours" - }, - "id": 442 - }, - "peyote": { - "name": "peyote", - "properties": { - "summary": "Peyote is a small, spineless cactus that contains mescaline as its primary active chemical. It has a long history of use among the natives of northern Mexico and SW United States.", - "duration": "4-8 hrs", - "onset": "60-120 minutes", - "after-effects": "6-8 hours", - "effects": "feelings of insight, brightening of colors, mood lift, closed and open eye visuals, giggling, increase in energy happy feelings, change in consciousness, loss of appettite, unusla thoughts and speech, mild to extreme distractability, changes in time and reality, changes in self control, ego softening, pupil dialation, body tremors, nausea, chest and neck pain, shortness of", - "dose": "Fresh Light: 50-100g Common: 100-150g Strong 150-200g Heavy: 200g+ | Dried Light: 10-20g Common: 20-30g Strong: 30-40g Heavy: 40g+", - "categories": [ - "psychedelic", - "common" - ] - }, - "pretty_name": "Peyote", - "categories": [ - "psychedelic", - "common" - ], - "formatted_dose": { - "Fresh": { - "Light": "50-100g", - "Common": "100-150g", - "Heavy": "200g+" - }, - "Dried": { - "Light": "10-20g", - "Common": "20-30g", - "Strong": "30-40g", - "Heavy": "40g+" - } - }, - "formatted_duration": { - "value": "4-8" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "feelings of insight", - "brightening of colors", - "mood lift", - "closed and open eye visuals", - "giggling", - "increase in energy happy feelings", - "change in consciousness", - "loss of appettite", - "unusla thoughts and speech", - "mild to extreme distractability", - "changes in time and reality", - "changes in self control", - "ego softening", - "pupil dialation", - "body tremors", - "nausea", - "chest and neck pain", - "shortness of" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Peyote.shtml" - }, - "formatted_aftereffects": { - "value": "6-8", - "_unit": "hours" - }, - "id": 443 - }, - "codeine": { - "name": "codeine", - "properties": { - "summary": "Codeine is a weaker opioid used to treat mild to moderate pain and to relieve cough. In many countries it is available over the counter in combination with paracetamol, which can easily be extracted to retrieve near-pure codeine. For this reason, it is used widely as a recreational opioid. It is metabolised into morphine in the body at a rate of 5% mg for mg.", - "avoid": "People seeking codeine experiences from medications that contain acetaminophen (paracetamol) may be putting themselves at risk for acetaminophen-related complications such as liver damage.", - "dose": "Oral Light: 50-100mg Common: 100-150mg Heavy: 150-200mg | NOTE: The ceiling effect differs from person to person, but it seems to fall between 400-600mg", - "duration": "3-6 hours", - "onset": "30-45 minutes", - "marquis": "Very dark purple", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "bioavailability": "Oral 90% | Rectal 90%", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "warning": "You must only use this drug orally due to the risk of severe immune system responses. It needs to pass through the liver to be activated anyway so IV, nasal, plugging etc do not offer an advantage", - "after-effects": "1-12 hours." - }, - "pretty_name": "Codeine", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-150mg", - "Heavy": "150-200mg" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Codeine.shtml" - }, - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: The ceiling effect differs from person to person, but it seems to fall between 400-600mg", - "sources": { - "_general": [ - "Codeine analgesia is due to codeine-6-glucuronide, not morphine. - https://www.ncbi.nlm.nih.gov/pubmed/11092114", - "Nod and wave: an Internet study of the codeine intoxication phenomenon. - https://www.ncbi.nlm.nih.gov/pubmed/25052240", - "Trends and characteristics of accidental and intentional codeine overdose deaths in Australia. - http://www.ncbi.nlm.nih.gov/pubmed/26424067", - "Rectal versus oral absorption of codeine phosphate in man. - http://www.ncbi.nlm.nih.gov/pubmed/6683976", - "Endogenous codeine and morphine in poor and extensive metabolisers of the CYP2D6 (debrisoquine/sparteine) polymorphism. - http://www.ncbi.nlm.nih.gov/pubmed/8113966" - ] - }, - "id": 444 - }, - "kava": { - "name": "kava", - "properties": { - "dose": "Oral Light: 50-70mg Common: 70-150mg Strong: 150-200mg Heavy: 300mg+ | NOTE: Doses are given for pure kavalactones, usually 5-20% of kava.", - "onset": "20-30 minutes", - "duration": "3-6 hours", - "after-effects": "9-18 hours.", - "summary": "Tropical evergreen shrub with large heart-shaped leaves and woody stems. Its thick roots are mashed or ground and made into a cold and bitter-tasting beverage used similarly to alcohol. It has a long history of ritual and recreational use in Pacific Polynesia and is now a common herbal product, used widely by those in certain societies as part of a 'Kava Culture.'", - "categories": [ - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Kava", - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-70mg", - "Common": "70-150mg", - "Strong": "150-200mg", - "Heavy": "300mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-30", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Kava.shtml" - }, - "formatted_aftereffects": { - "value": "9-18", - "_unit": "hours" - }, - "dose_note": " NOTE: Doses are given for pure kavalactones, usually 5-20% of kava.", - "sources": { - "_general": [ - "clinical trials show that Kava significantly lowers anxiety compared to placebo - Mosby's Dental Drug Reference Ninth Edition 2010" - ] - }, - "id": 445 - }, - "bromazepam": { - "name": "bromazepam", - "properties": { - "summary": "A benzodiazepine drug with a medium-long duration, developed by Roche in the 1960s. Has primarily anxiolytic properties. May cause lowered inhibitions and amnesia in high doses.", - "dose": "Oral Light: 2.5-5mg Common: 5-10mg Heavy: 10-15mg+ | NOTE: 6mg of Bromazepam is approximately equivelant to 10mg Diazepam", - "onset": "10-20 minutes.", - "duration": "4-8 hours.", - "avoid": "All other CNS depressants.", - "aliases": [ - "lectopam", - "lexilium", - "lexotan", - "brazepam", - "lexotanil" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia.", - "bioavailability": "Oral: 84%.", - "after-effects": "1-16 hours.", - "dose_to_diazepam": "Bromazepam - 5-6mg's ~=10mg Diazepam." - }, - "pretty_name": "Bromazepam", - "aliases": [ - "lectopam", - "lexilium", - "lexotan", - "brazepam", - "lexotanil" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-10mg", - "Heavy": "10-15mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-20", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "" - ], - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "dose_note": " NOTE: 6mg of Bromazepam is approximately equivelant to 10mg Diazepam", - "sources": { - "_general": [ - "Bioavailability of bromazepam in man after single administration of an oral solution. http://www.ncbi.nlm.nih.gov/pubmed/6142717" - ] - }, - "id": 446 - }, - "nitrazepam": { - "name": "nitrazepam", - "properties": { - "dose": "Light: 2-5mg Common: 5-15mg Strong: 15-20mg Heavy: 20-30mg+", - "summary": "Hypnotic Benzodiazepine, that is used for short term relief of anxiety and insomnia. It has a pronouced affect on respritory action.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "duration": "5-8 hours.", - "after-effects": "6-12 hours", - "onset": "10-40 minutes", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "aliases": [ - "mogadon", - "baronite", - "dormin", - "dreem", - "enzed", - "gentravit", - "hypnonex", - "hypnoril", - "hypnotex", - "konit", - "nicare", - "nigap", - "nipam", - "nirosun", - "nitavan", - "nithra" - ], - "dose_to_diazepam": "Nitrazepam - 10mg ~=10mg Diazepam." - }, - "pretty_name": "Nitrazepam", - "aliases": [ - "mogadon", - "baronite", - "dormin", - "dreem", - "enzed", - "gentravit", - "hypnonex", - "hypnoril", - "hypnotex", - "konit", - "nicare", - "nigap", - "nipam", - "nirosun", - "nitavan", - "nithra" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2-5mg", - "Common": "5-15mg", - "Strong": "15-20mg", - "Heavy": "20-30mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "6-12", - "_unit": "hours" - }, - "id": 447 - }, - "norflurazepam": { - "name": "norflurazepam", - "properties": { - "summary": "Benzodiazepine analogue that is an active metabolite to many other benzodiazepines, such as Flurazepam, Flutoprazepam, and Midazolam.", - "onset": "45-120 minutes.", - "duration": "10-16 hours.", - "avoid": "All other CNS depressants.", - "dose": "Light: 2-5mg Common: 5-10mg Strong: 10-20mg+", - "aliases": [ - "n-desalkylflurazepam" - ], - "categories": [ - "benzodiazepine", - "depressant", - "tentative", - "habit-forming" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Norflurazepam", - "aliases": [ - "n-desalkylflurazepam" - ], - "categories": [ - "benzodiazepine", - "depressant", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "value": "10-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 448 - }, - "fluorophenibut": { - "name": "fluorophenibut", - "properties": { - "summary": "An anxiolytic analogue of GABA and Phenibut, with similar activity to the latter. Expected to be 5-10 times as potent as phenibut, some preliminary reports suggest tolerance builds more slowly.", - "dose": "Light: 50-100mg Common: 100-150mg Strong: 200-250mg+", - "duration": "8-12 hours.", - "onset": "60-120 minutes.", - "categories": [ - "tentative", - "depressant", - "habit-forming" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Fluorophenibut", - "categories": [ - "tentative", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-150mg", - "Strong": "200-250mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 449 - }, - "ethaqualone": { - "name": "ethaqualone", - "properties": { - "dose": "Oral Light: 100-175mg Common: 175-300mg Strong: 300-450mg", - "duration": "Oral: 4-6 hours.", - "onset": "Oral: 30-45 minutes.", - "avoid": "All other CNS depressants.", - "after-effects": "Oral: 2-6 hours.", - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "depressant" - ], - "summary": "Analogue of Methaqualone that was mostly marketed in France. Slightly weaker and shorter acting than the prior.", - "aliases": [ - "etaqualone" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic." - }, - "pretty_name": "Ethaqualone", - "aliases": [ - "etaqualone" - ], - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "100-175mg", - "Common": "175-300mg", - "Strong": "300-450mg" - } - }, - "formatted_duration": { - "Oral": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Etaqualone.shtml" - }, - "formatted_aftereffects": { - "Oral": "2-6", - "_unit": "hours" - }, - "id": 450 - }, - "3-meo-pcpr": { - "name": "3-meo-pcpr", - "properties": { - "summary": "This is the N-Propyl homologue of 3-MeO-PCE. It is slightly less potent than PCP. Yet seems slightly less manic inducing.", - "duration": "Oral: 3-4 hours. || Insufflated: 1-3 hours.", - "onset": "Oral: 15-30 minutes. || Insufflated: 5-10 mintues.", - "dose": "Oral Light: 5-8mg Common: 8-15mg Strong: 15-20mg+ || Insufflated Light: 1-3mg Common: 3-8mg Strong: 8-15mg+", - "categories": [ - "dissociative", - "tentative", - "research-chemical", - "habit-forming" - ], - "after-effects": "1-4 hours." - }, - "pretty_name": "3-MeO-PCPR", - "categories": [ - "dissociative", - "tentative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-8mg", - "Common": "8-15mg", - "Strong": "15-20mg+" - }, - "": {}, - "Insufflated": { - "Light": "1-3mg", - "Common": "3-8mg", - "Strong": "8-15mg+" - } - }, - "formatted_duration": { - "Oral": "3-4", - "Insufflated": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 451 - }, - "d2pm": { - "name": "d2pm", - "properties": { - "summary": "An NDRI, which is reported as being rather lackluster.", - "duration": "2-5 hours.", - "dose": "Light: 15-20mg Common: 20-35mg Strong: 35-50mg+ | NOTE: These doses are tentative and may need further research.", - "avoid": "Other stimulants.", - "onset": "20-30 minutes", - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ], - "aliases": [ - "diphenylprolinol" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "D2PM", - "aliases": [ - "diphenylprolinol" - ], - "categories": [ - "stimulant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Light:": { - "Light": "15-20mg", - "Common": "20-35mg", - "Strong": "35-50mg+" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 452 - }, - "5-meo-dpt": { - "name": "5-meo-dpt", - "properties": { - "summary": "A rare tryptamine psychedelic and analogue of DPT. Little is known about this compound but it is likely to have effects similar to DPT, DMT and others related compounds.", - "duration": "2-5 hours", - "after-effects": "1-2 hours.", - "dose": "Oral Light: 3mg Common: 3-5mg Strong: 5-10mg+ | NOTE: These doses are tentative and may need further research.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "onset": "30-60 minutes.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "5meodpt" - ] - }, - "pretty_name": "5-MeO-DPT", - "aliases": [ - "5meodpt" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "3mg", - "Common": "3-5mg", - "Strong": "5-10mg+" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_5MeODPT.shtml" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are tentative and may need further research.", - "id": 453 - }, - "2c-i": { - "name": "2c-i", - "properties": { - "dose": "Oral Threshold: 2-5mg Light: 5-15mg Common: 10-25mg Strong: 20-30mg | Insufflated Threshold: 0.5-2mg Common: 5-10mg Strong: 10mg+", - "duration": "Oral: 4-12 Hours | Insufflated: 4-8 hours", - "effects": "euphoria, giggling, empathy, insight, brightened color, closed/open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception of time, ego softening, nausea, sweating/chills, muscle tension, confusion, insomnia", - "onset": "45-120 minutes", - "summary": "A psychedelic similar to the more well-known 2C-B. Users frequently report very vivid and bright open-eye visuals and more mild closed-eye visuals compared to 2C-B and other drugs in the 2C family. Can also be more stimulating than 2C-B along with having a slight body load for some users. Less safe at high doses compared to 2C-B", - "aliases": [ - "2ci" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "after-effects": "4-12 hours", - "test-kits": "Marquis: Yellow > Green/Blue. | Mecke: Brown > Black. | Mandelin: (Pale) Brown > Black. | Simon's: Red > Orange. | Ehrlich: Brown." - }, - "pretty_name": "2C-I", - "aliases": [ - "2ci" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "2-5mg", - "Light": "5-15mg", - "Common": "10-25mg", - "Strong": "20-30mg" - }, - "Insufflated": { - "Threshold": "0.5-2mg", - "Common": "5-10mg", - "Strong": "10mg+" - } - }, - "formatted_duration": { - "Oral": "4-12", - "Insufflated": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "euphoria", - "giggling", - "empathy", - "insight", - "brightened color", - "closed/open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception of time", - "ego softening", - "nausea", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CI.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal033.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "4-12", - "_unit": "hours" - }, - "id": 454 - }, - "furanylfentanyl": { - "name": "furanylfentanyl", - "properties": { - "summary": "An extremely potent opioid analgesic and analogue of fentanyl. Concrete information is difficult to obtain about even basic properties like active dose, though it is believed to be slightly less potent and shorter in duration than butyrfentanyl. Exercise extreme caution. Will cause respiratory depression in overdose.", - "dose": "Oral Light: 300-500ug Common: 500-900ug Strong: 900-1600ug+. | Insufflated Light: 200-400ug Common: 400-800ug Strong: 800-1600ug+ | NOTE: Very potent opioid, be very careful while dosing.", - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "opioid", - "depressant" - ], - "aliases": [ - "fu-f", - "furanyl-fentanyl" - ], - "duration": "1-3 hours.", - "onset": "1-10 minutes.", - "after-effects": "1-3 hours." - }, - "pretty_name": "Furanylfentanyl", - "aliases": [ - "fu-f", - "furanyl-fentanyl" - ], - "categories": [ - "research-chemical", - "habit-forming", - "tentative", - "opioid", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "300-500ug", - "Common": "500-900ug", - "Strong": "900-1600ug+." - }, - "Insufflated": { - "Light": "200-400ug", - "Common": "400-800ug", - "Strong": "800-1600ug+" - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-3", - "_unit": "hours" - }, - "dose_note": " NOTE: Very potent opioid, be very careful while dosing.", - "id": 455 - }, - "gaba": { - "name": "gaba", - "properties": { - "onset": "Oral: 15-60 minutes.", - "dose": "Oral Light: 200-400mg Common: 400-800mg Strong: 800-1600mg+", - "summary": "Gamma-Aminobutyric Acid. Supplement used in calming some down. Does not pass the brain blood barrier.", - "categories": [ - "depressant", - "supplement" - ], - "duration": "Oral: 5-8 hours.", - "after-effects": "1-2 hours." - }, - "pretty_name": "GABA", - "categories": [ - "depressant", - "supplement" - ], - "formatted_dose": { - "Oral": { - "Light": "200-400mg", - "Common": "400-800mg", - "Strong": "800-1600mg+" - } - }, - "formatted_duration": { - "Oral": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_GABA.shtml" - }, - "formatted_aftereffects": { - "value": "1-2", - "_unit": "hours" - }, - "id": 456 - }, - "benzydamine": { - "name": "benzydamine", - "properties": { - "summary": "NSAID with local anesthetic and analgesic properties, similar to ibuprofen or naproxen. Sometimes abused in overdose with reported delirant and stimulant effects.", - "onset": "15-60 minutes.", - "duration": "4-8 hours.", - "categories": [ - "deliriant", - "tentative", - "stimulant" - ], - "aliases": [ - "tantum" - ], - "dose": "Light: 250-500mg Common: 500-1000mg Strong: 1000-1500mg+", - "after-effects": "2-48 hours." - }, - "pretty_name": "Benzydamine", - "aliases": [ - "tantum" - ], - "categories": [ - "deliriant", - "tentative", - "stimulant" - ], - "formatted_dose": { - "Oral": { - "Light": "250-500mg", - "Common": "500-1000mg", - "Strong": "1000-1500mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-60", - "_unit": "minutes" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Visual haze": "https://psychonautwiki.org/wiki/Visual_haze" - }, - "formatted_aftereffects": { - "value": "2-48", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Recreational abuse with benzydamine hydrochloride (tantum rosa). http://www.ncbi.nlm.nih.gov/pubmed/17364645", - "Recreational use of benzydamine as a hallucinogen among street youth in Brazil. http://www.ncbi.nlm.nih.gov/pubmed/19784487" - ] - }, - "id": 457 - }, - "4-fa": { - "name": "4-fa", - "properties": { - "summary": "An empathogen commonly used in place of MDMA, having a similar duration of empathogenic effects. This drug, however, has a longer stimulant \"tail,\" during which effects are more like those of amphetamines. Not to be confused with 4-FMA, which has a similar potency, but is not particularly empathogenic.", - "aliases": [ - "4-Fluoroamphetamine", - "4fa", - "4-fmp", - "4-fluoroamphetamine" - ], - "dose": "Oral Light: 50-70mg Common: 70-110mg Heavy: 115-150mg | NOTE: Insufflating does not appear to provide a better bioavailability than oral ingestion, and can cause damage to nasal cavity.", - "duration": "4-8 hours", - "onset": "Oral: 30-90 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "empathogen", - "common" - ], - "avoid": "Other stimulants, and depressants. MXE is also to be avoided (possibility of serotonin syndrome). See combo information for more.", - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness.", - "after-effects": "1-24 hours.", - "4-fa": "dose: Oral Light: 50-70mg Common: 70-110mg Heavy: 115-150mg | NOTE: Insufflating does not appear to provide a better bioavailability than oral ingestion, and can cause damage to nasal cavity." - }, - "pretty_name": "4-FA", - "aliases": [ - "4-Fluoroamphetamine", - "4fa", - "4-fmp", - "4-fluoroamphetamine" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "empathogen", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "50-70mg", - "Common": "70-110mg", - "Heavy": "115-150mg" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4Fluoroamphetamine.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Ego inflation": "https://psychonautwiki.org/wiki/Ego_inflation", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Insufflating does not appear to provide a better bioavailability than oral ingestion, and can cause damage to nasal cavity.", - "sources": { - "_general": [ - "Comparison of 4-chloro-, 4-bromo- and 4-fluoroamphetamine in rats: drug levels in brain and effects on brain serotonin metabolism. - https://www.ncbi.nlm.nih.gov/pubmed/1196472", - "4-Fluoroamphetamine, in contrast, lowered serotonin and 5-hydroxyindoleacetic acid levels only for short times (2–6 hr) after drug injection, and 5-hydroxyindole levels were essentially back to normal within 24 hr. - http://www.sciencedirect.com/science/article/pii/0028390875900994" - ] - }, - "id": 458 - }, - "pfbt": { - "name": "pfbt", - "properties": { - "summary": "Tropane derivative substance that supposedly has around ~30% the potency of Cocaine as a stimulant. While also having properties of a local anasthetic.", - "aliases": [ - "4-fluorotropacocaine" - ], - "dose": "Insufflated Threshold: 10-20mg Light: 20-50mg Common: 50-70mg Strong: 70-110mg+", - "onset": "Insufflated: 1-10 minutes.", - "duration": "Insufflated: 1-2 hours.", - "after-effects": "1-24 hours.", - "categories": [ - "stimulant", - "habit-forming", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "PFBT", - "aliases": [ - "4-fluorotropacocaine" - ], - "categories": [ - "stimulant", - "habit-forming", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Insufflated": { - "Threshold": "10-20mg", - "Light": "20-50mg", - "Common": "50-70mg", - "Strong": "70-110mg+" - } - }, - "formatted_duration": { - "Insufflated": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "1-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 459 - }, - "2c-t-7": { - "name": "2c-t-7", - "properties": { - "dose": "Oral Light: 10-20mg Common: 15-30mg Strong: 30-40mg Heavy: 40mg+ | NOTE: 2C-T-7 reacts widely in varying ways. Start low, work your way up.", - "risks": "There have been several reports of deaths from 2C-T-7, and many reports of severe dissociation and vomiting (a dangerous combination) after both oral and insufflated use.", - "onset": "Oral: 20-140 minutes | Insufflated 20-90 minutes.", - "duration": "Oral: 6-12 hours | Insufflated 2-5 hours.", - "after-effects": "4-12 hours", - "avoid": "Do not take if currently taking a MAOI.", - "aliases": [ - "2ct7" - ], - "summary": "A relatively uncommon psychedelic phenethylamine and possible MAOI. Long lasting, an possesses an unpredictable dosage curve. Questionable safety in combination with most things.", - "categories": [ - "research-chemical", - "empathogen", - "psychedelic" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "test-kits": "Marquis: Fizzes Pale Orange. | Mecke: Red > Purple. | Mandelin: Red > Purple. | Froehde: Violet Orange | Liebermann: Deep Purple. | Simon's Red > Brown. | Ehrlich: No colour change." - }, - "pretty_name": "2C-T-7", - "aliases": [ - "2ct7" - ], - "categories": [ - "research-chemical", - "empathogen", - "psychedelic" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "15-30mg", - "Strong": "30-40mg", - "Heavy": "40mg+" - } - }, - "formatted_duration": { - "Oral": "6-12", - "Insufflated": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "20-140", - "Insufflated": "20-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CT7.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal043.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "4-12", - "_unit": "hours" - }, - "dose_note": " NOTE: 2C-T-7 reacts widely in varying ways. Start low, work your way up.", - "sources": { - "_general": [ - "Sulfur-Substituted α-Alkyl Phenethylamines as Selective and Reversible MAO-A Inhibitors:  Biological Activities, CoMFA Analysis, and Active Site Modeling http://pubs.acs.org/doi/abs/10.1021/jm0493109" - ] - }, - "id": 460 - }, - "changa": { - "name": "changa", - "properties": { - "summary": "Changa is the name given to a smoking blend of caapi or other MAOI containing plants with an infusion of extracted DMT. Changa often contains other milder psychoactive herbs as well. The maoi action results in a longer and more intense trip (see Ayahuasca) NOTE: There is no standardized recipe or concentration of infused DMT, therefor dosage and potency will vary per batch.", - "dose": "Light: 5-15mg Common: 15-30mg Strong: 30-50mg Heavy: 50+mg | NOTE: These are tentative estimates as Changa potency and dosing will vary per batch/source.", - "onset": "0-2 minutes", - "duration": "6-12 minutes", - "after-effects": "1-36 hours", - "effects": "immersive experience, open eye visuals, radical perspective shifting, profound life-changing spiritual experiences, powerful rushing of sensation, change in perception of time, auditory hallucinations, color shifting, hard on lungs when smoking, stomach discomfort, difficulty integrating experiences, overwhelming fear", - "categories": [ - "psychedelic", - "tentative" - ], - "avoid": "combining with any medications or substance contraindicated with MAOI's particuarly ssri's, mdxx compounds and amphetamines. Refer to http://wiki.tripsit.me/wiki/Drug_combinations for more info." - }, - "pretty_name": "Changa", - "categories": [ - "psychedelic", - "tentative" - ], - "formatted_dose": { - "Light:": { - "Light": "5-15mg", - "Common": "15-30mg", - "Strong": "30-50mg", - "Heavy": "50+mg" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "0-2", - "_unit": "minutes" - }, - "formatted_effects": [ - "immersive experience", - "open eye visuals", - "radical perspective shifting", - "profound life-changing spiritual experiences", - "powerful rushing of sensation", - "change in perception of time", - "auditory hallucinations", - "color shifting", - "hard on lungs when smoking", - "stomach discomfort", - "difficulty integrating experiences", - "overwhelming fear" - ], - "formatted_aftereffects": { - "value": "1-36", - "_unit": "hours" - }, - "dose_note": " NOTE: These are tentative estimates as Changa potency and dosing will vary per batch/source.", - "id": 461 - }, - "palfium": { - "name": "palfium", - "properties": { - "summary": "Dextromoramide, a rare and powerful opioid analgesic approximately three times as potent as morphine with a shorter duration. Generally only seen in the Netherlands. Reported as having strange and rapid tolerance behaviour.", - "dose": "Oral Light: 2.5-5mg Common: 5-7.5mg Strong: 7.5-10mg+ | NOTE: Read ~summary before you take this drug. It's very unpredictable.", - "onset": "Oral: 5-15 minutes. | Intravenously: 1-2 minutes.", - "duration": "Oral 3-5 hours. | Intravenously: 2-3 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "aliases": [ - "dextromoramide" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Dextromoramide", - "aliases": [ - "dextromoramide" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "2.5-5mg", - "Common": "5-7.5mg", - "Strong": "7.5-10mg+" - } - }, - "formatted_duration": { - "Oral": "3-5", - "Intravenously": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "5-15", - "Intravenously": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Read ~summary before you take this drug. It's very unpredictable.", - "id": 462 - }, - "allylescaline": { - "name": "allylescaline", - "properties": { - "duration": "8-12 hours. Varies greatly on dose.", - "onset": "45-240 minutes", - "dose": "Oral Threshold: 15-20mg Light: 20-30mg Common: 30-40mg Strong: 40-60mg+", - "aliases": [ - "al" - ], - "summary": "Mescaline analogue with a much lower dose, that seems to rely heavily on colours.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-16 hours." - }, - "pretty_name": "Allylescaline", - "aliases": [ - "al" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "15-20mg", - "Light": "20-30mg", - "Common": "30-40mg", - "Strong": "40-60mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-240", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Allylescaline.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal002.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "id": 463 - }, - "2-nmc": { - "name": "2-nmc", - "properties": { - "summary": "Inactive.", - "categories": [ - "inactive" - ] - }, - "pretty_name": "2-NMC", - "categories": [ - "inactive" - ], - "id": 464 - }, - "vyvanse": { - "name": "vyvanse", - "properties": { - "summary": "Also known as lisdexamphetamine, this drug is a CNS stimulant often prescribed for ADHD, narcolepsy and obesity. It is also a pro-drug for dextroamphetamine, and functions as a method for providing extended-release stimulation. It is sometimes prescribed alongside an SSRI for depression.", - "aliases": [ - "lisdextroamfetamine", - "lisdextroamphetamine", - "lisdexamphetamine", - "lisdexamfetamine" - ], - "dose": "Oral Light: 20-30mg Common: 30-50mg Strong: 50-100mg+ | Note: Vyvanse is the same orally and insufflated - it is pointless to insufflate.", - "effects": "Increased alertness, Euphoria, Increased motivation, Reduced appetite, Flushing of the face, Increased body temperature, Tachycardia (Increased heart rate), Paranoia, Insomnia.", - "duration": "Oral: 6-14 hours. | NOTE: Dependant on dose and tolerance.", - "onset": "Oral: 60-90 minutes | NOTE: Onset is delayed by 1 additional hour when taken with a meal high in fat.", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "after-effects": "Oral: 1-16 hours. | Note: Highly dependant on dose." - }, - "pretty_name": "Vyvanse", - "aliases": [ - "lisdextroamfetamine", - "lisdextroamphetamine", - "lisdexamphetamine", - "lisdexamfetamine" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "20-30mg", - "Common": "30-50mg", - "Strong": "50-100mg+" - } - }, - "formatted_duration": { - "Oral": "6-14", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "60-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Increased alertness", - "Euphoria", - "Increased motivation", - "Reduced appetite", - "Flushing of the face", - "Increased body temperature", - "Tachycardia (Increased heart rate)", - "Paranoia", - "Insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Lisdexamfetamine.shtml" - }, - "formatted_aftereffects": { - "Oral": "1-16", - "_unit": "hours" - }, - "dose_note": " Note: Vyvanse is the same orally and insufflated - it is pointless to insufflate.", - "sources": { - "onset": [ - "is delayed by 1 additional hour when taken with a high fat meal - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873712/" - ], - "_general": [ - "Use of naltrexone has been found to successfully aid in recovery from amphetamine addiction - http://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2008.08020304", - "Vyvanse is approved for and proven to be affective for the treatment of binge-eating disorder in adults - http://onlinelibrary.wiley.com/doi/10.1111/ijcp.12639/full", - "Vyvanse has been proven to be effectivein treating attention deficits in patients with traumatic brain injuries - http://www.tandfonline.com/doi/abs/10.3109/02699052.2014.930179", - "For serotonin syndrome secondary to vyvanse overdose, dexmedetomidine may be used for treatment when standard treatment protocols do not work - http://aop.sagepub.com/content/48/12/1651.abstract", - "Vyvanse when used intravenously was proven to not have increased abuse liability, which implies that it does not have increased euphoria - http://jop.sagepub.com/content/early/2008/07/17/0269881108093841.short" - ] - }, - "id": 465 - }, - "coluracetam": { - "name": "coluracetam", - "properties": { - "onset": "Oral: 15-30 minutes. | Sublingual: 5-10 minutes. | Intranasal: 1-5 minutes", - "duration": "3-6 hours depending on stomach contents/ROA/ect.", - "dose": "Oral Light: 3-5mg Common: 5-10mg Strong: 10-20mg+ | Sublingual/Insufflated Light: 2-5mg Common: 5-10mg Strong: 10mg+", - "summary": "A nootropic drug of the racetam class, originally developed to treat Alzheimer's disease, it is currently being investigated as a treatment for major depressive disorder and generalised anxiety disorder. May be a modulator of the AMPA receptor. Limited recreational value.", - "categories": [ - "research-chemical", - "nootropic" - ], - "after-effects": "1-4 hours." - }, - "pretty_name": "Coluracetam", - "categories": [ - "research-chemical", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Light": "3-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - }, - "Sublingual/Insufflated": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Sublingual": "5-10", - "Intranasal": "1-5", - "_unit": "minutes" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 466 - }, - "al-lad": { - "name": "al-lad", - "properties": { - "onset": "45-120 minutes.", - "dose": "Light: 40-75ug Common: 75-175ug Strong: 175-250ug Heavy: 250ug+", - "effects": "Similar in effect to LSD, open and closed eye visuals are common. Auditory hallucinations are reported as common. A sense of connectedness with people and the environment around you. A strong sense of wellbeing.", - "duration": "4-6 hours", - "summary": "AL-LAD is a hallucinogenic drug, lysergamide and an analogue of LSD. It is reported as having some subtle experiential differences to LSD (such as increased visuals), and also appears to be slightly shorter lasting. AL-LAD doses are similar to those of LSD, depending on purity. Its availability on the Internet since 2013 has lead to strong popularity among the drug community.", - "aliases": [ - "allad" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "after-effects": "1-24 hours." - }, - "pretty_name": "AL-LAD", - "aliases": [ - "allad" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "40-75ug", - "Common": "75-175ug", - "Strong": "175-250ug", - "Heavy": "250ug+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Similar in effect to LSD", - "open and closed eye visuals are common", - "Auditory hallucinations are reported as common", - "A sense of connectedness with people and the environment around you", - "A strong sense of wellbeing", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_ALLAD.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal01.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depth perception distortions": "https://psychonautwiki.org/wiki/Depth_perception_distortions", - "Diffraction": "https://psychonautwiki.org/wiki/Diffraction", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Multiple thought streams": "https://psychonautwiki.org/wiki/Multiple_thought_streams", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 467 - }, - "dmaa": { - "name": "dmaa", - "properties": { - "summary": "Also known as methylhexanamine, this sympathetomimetic drug was developed as a nasal decongestant by Eli Lilly in the 1940s. It has been used as a weight loss aid and missold as a dietary supplement and component of some energy drinks. Carries a risk of heart attack, stroke and other life-threatening cardiovascular issues.", - "dose": "Threshold: 5-10mg Low: 10-20mg Common: 20-50mg Strong: 50-100mg", - "duration": "2-4 hours.", - "onset": "Rapid.", - "avoid": "Other stimulants.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "nootropic" - ] - }, - "pretty_name": "DMAA", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Low": "10-20mg", - "Common": "20-50mg", - "Strong": "50-100mg" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Rapid." - }, - "id": 468 - }, - "crl-40-941": { - "name": "crl-40-941", - "properties": { - "summary": "A substance closely related to Adrafinil and Modafinil. It is the bis(p-fluoro) ring derivative of Adrafinil.", - "aliases": [ - "fladrafinil", - "fluoromodafinil" - ], - "onset": "30-90 minutes.", - "duration": "6-14 hours. Dependant on dose.", - "dose": "Light: 50-100mg Common: 100-250mg Strong: 250-350mg+", - "categories": [ - "stimulant", - "tentative", - "nootropic", - "research-chemical" - ], - "after-effects": "1-10 hours." - }, - "pretty_name": "CRL-40-941", - "aliases": [ - "fladrafinil", - "fluoromodafinil" - ], - "categories": [ - "stimulant", - "tentative", - "nootropic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-250mg", - "Strong": "250-350mg+" - } - }, - "formatted_duration": { - "value": "6-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-10", - "_unit": "hours" - }, - "id": 469 - }, - "mipt": { - "name": "mipt", - "properties": { - "summary": "N-Methyl-N-isopropyltryptamine, a tryptamine analogue of DMT, a very uncommon drug with very few reports of human use. Described as 'more psychedelic than hallucinogenic' users report only mild visuals with some stimulation and cognitive effects. One of the more stable tryptamines.", - "dose": "Oral Light: 5-10mg Common: 10-15mg Strong: 15-25mg+ | Insufflated Light: 5-10mg Common: 10-15mg Strong: 15-20mg+ | Vapourized Light: 3-5mg Common: 5-15mg Strong: 15-20mg+", - "onset": "Oral: 30-45 minutes. | Insufflated: 0-2 minutes | Vapourized: 0-1 minutes", - "duration": "Oral: 2-5 hours. | Insufflated 3-5 hours. | Vapourized 2-3 hours.", - "aliases": [ - "n-methyl-n-isopropyltryptamine" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-6 hours." - }, - "pretty_name": "MiPT", - "aliases": [ - "n-methyl-n-isopropyltryptamine" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-25mg+" - }, - "Insufflated": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-20mg+" - }, - "Vapourized": { - "Light": "3-5mg", - "Common": "5-15mg", - "Strong": "15-20mg+" - } - }, - "formatted_duration": { - "Oral": "2-5", - "Insufflated": "3-5", - "Vapourized": "2-3", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-45", - "Insufflated": "0-2", - "Vapourized": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MIPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal47.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 470 - }, - "halazepam": { - "name": "halazepam", - "properties": { - "summary": "A less common prescription benzodiazepine and derivative of Nordazepam. Also known as Paxipam, it is no longer prescribed in the USA. Sedating, hypnotic and anxiolytic. High doses may induce amnesia and lowered inhibitions.", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "dose": "Light: 10-20mg Common: 20-40mg Strong: 40-80mg+", - "onset": "15-45 minutes.", - "duration": "8-14 hours.", - "after-effects": "12-40 hours.", - "avoid": "All other CNS depressants.", - "aliases": [ - "paxipam" - ], - "dose_to_diazepam": "Halazepam - 20mg ~=10mg Diazepam." - }, - "pretty_name": "Halazepam", - "aliases": [ - "paxipam" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "10-20mg", - "Common": "20-40mg", - "Strong": "40-80mg+" - } - }, - "formatted_duration": { - "value": "8-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "12-40", - "_unit": "hours" - }, - "id": 471 - }, - "lsd": { - "name": "lsd", - "properties": { - "dose": "Oral Light: 50-100ug Common: 100-150ug Strong: 175-225ug Heavy: 250ug+ | Note: These doses are for pure LSD, note that tabs are often rather a lot weaker than they are advertised.", - "duration": "9-14 hours, varying with dosage (heavy doses can lead to much longer trips).", - "onset": "45-90 minutes depending on ROA and stomach contents.", - "effects": "visual distortions, a sense of childlike wonder, brightening of colors,racing thoughts, hue shifts, euphoria, anxiety, confusion", - "avoid": "marijuana (Can potentiate effects)", - "aliases": [ - "lsd-25", - "acid", - "cid", - "lucy" - ], - "marquis": "Olive black", - "summary": "LSD is a popular psychedelic with a relatively long history of use and research, and as such is known to be relatively safe despite its extremely high potency. It is the archetypical psychedelic to which all others are compared, and remains in popular usage.", - "categories": [ - "psychedelic", - "common" - ], - "half-life": "3-5 hours", - "after-effects": "12-24 hours", - "oral": "Light: 50-100ug Common: 100-150ug Strong: 175-225ug Heavy 225ug+ | Note: These doses are for pure LSD, note that tabs are often rather a lot weaker than they are advertised." - }, - "pretty_name": "LSD", - "aliases": [ - "lsd-25", - "acid", - "cid", - "lucy" - ], - "categories": [ - "psychedelic", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100ug", - "Common": "100-150ug", - "Strong": "175-225ug", - "Heavy": "250ug+" - } - }, - "formatted_duration": { - "value": "9-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "visual distortions", - "a sense of childlike wonder", - "brightening of colors", - "racing thoughts", - "hue shifts", - "euphoria", - "anxiety", - "confusion" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_LSD.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal26.shtml" - }, - "pweffects": { - "8A Geometry - Exposure to semantic concept network": "https://psychonautwiki.org/wiki/8A_Geometry_-_Exposure_to_semantic_concept_network", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depth perception distortions": "https://psychonautwiki.org/wiki/Depth_perception_distortions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Feelings of eternalism": "https://psychonautwiki.org/wiki/Feelings_of_eternalism", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Feelings of self-design": "https://psychonautwiki.org/wiki/Feelings_of_self-design", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Laughter": "https://psychonautwiki.org/wiki/Laughter", - "Magnification": "https://psychonautwiki.org/wiki/Magnification", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Multiple thought streams": "https://psychonautwiki.org/wiki/Multiple_thought_streams", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Personal meaning enhancement": "https://psychonautwiki.org/wiki/Personal_meaning_enhancement", - "Personality regression": "https://psychonautwiki.org/wiki/Personality_regression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Recursion": "https://psychonautwiki.org/wiki/Recursion", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Simultaneous emotions": "https://psychonautwiki.org/wiki/Simultaneous_emotions", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation" - }, - "formatted_aftereffects": { - "value": "12-24", - "_unit": "hours" - }, - "dose_note": " Note: These doses are for pure LSD, note that tabs are often rather a lot weaker than they are advertised.", - "sources": { - "_general": [ - "Agonistic activity of LSD and lisuride at cloned 5HT2A and 5HT2C receptors - http://www.ncbi.nlm.nih.gov/pubmed/9600588", - "Alterations in responses to LSD in humans associated with chronic administration of tricyclic antidepressants, monoamine oxidase inhibitors or lithium... - http://www.ncbi.nlm.nih.gov/pubmed/8788508", - "Chronic administration of serotonergic antidepressants attenuates the subjective effects of LSD in humans - http://www.ncbi.nlm.nih.gov/pubmed/8726753", - "LSD toxicity: a suspected cause of death - http://www.ncbi.nlm.nih.gov/pubmed/845494", - "Influence of naloxone on the effects of LSD in monkeys. - http://www.ncbi.nlm.nih.gov/pubmed/6527737", - "Coma, hyperthermia and bleeding associated with massive LSD overdose. A report of eight cases - http://www.ncbi.nlm.nih.gov/pubmed/4816396", - "Ascorbic acid antagonizes the behavioural effects of LSD in cats - http://www.ncbi.nlm.nih.gov/pubmed/2868111", - "Illicit use of LSD or psilocybin, but not MDMA or nonpsychedelic drugs, is associated with mystical experiences in a dose-dependent manner - http://www.ncbi.nlm.nih.gov/pubmed/23457892", - "New Onset LSD Flashback Syndrome Triggered by the Initiation of SSRIs - http://www.ncbi.nlm.nih.gov/pubmed/21603479", - "LSD and tryptamine effects on sleep/wakefulness and electrocorticogram patterns in intact cats - http://www.ncbi.nlm.nih.gov/pubmed/210478", - "Characterization of behavioral and endocrine effects of LSD on zebrafish - http://www.ncbi.nlm.nih.gov/pubmed/20561961", - "Drug dreams in mescaline and LSD addiction - http://www.ncbi.nlm.nih.gov/pubmed/20163393", - "Response of cluster headache to psilocybin and LSD - http://www.ncbi.nlm.nih.gov/pubmed/16801660", - "LSD flashback syndrome exacerbated by selective serotonin reuptake inhibitor antidepressants in adolescents - https://www.ncbi.nlm.nih.gov/pubmed/7965440", - "Metabolism of lysergic acid diethylamide (LSD) to 2-oxo-3-hydroxy LSD (O-H-LSD) in human liver microsomes and cryopreserved human hepatocytes - https://www.ncbi.nlm.nih.gov/pubmed/11043658", - "LSD-induced entropic brain activity predicts subsequent personality change. - https://www.ncbi.nlm.nih.gov/pubmed/27151536" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Low Risk & Synergy" - }, - "nbomes": { - "status": "Low Risk & Synergy" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Low Risk & Synergy" - }, - "amt": { - "status": "Low Risk & Synergy" - }, - "5-meo-xxt": { - "status": "Low Risk & Synergy" - }, - "cannabis": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & Synergy" - }, - "pcp": { - "status": "Low Risk & Synergy" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "mdma": { - "status": "Low Risk & Synergy" - }, - "cocaine": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "caffeine": { - "status": "Low Risk & No Synergy" - }, - "alcohol": { - "status": "Low Risk & Decrease" - }, - "ghb/gbl": { - "status": "Low Risk & Decrease" - }, - "opioids": { - "status": "Low Risk & No Synergy" - }, - "tramadol": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures." - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Low Risk & Decrease" - }, - "ssris": { - "status": "Low Risk & Decrease" - } - }, - "id": 472 - }, - "medazepam": { - "name": "medazepam", - "properties": { - "summary": "Benzodiazepine derivative that has all of the classic benzodiazepine effects. Is a long-acting benzodiazepine drug (Half life of 36-200 hours) Is rarely prescribed in most countries. Is also a prodrug for Diazepam. Think of it as Desoxy-Diazepam if you'd like to.", - "dose": "Light: 5-10mg Common: 10-20mg Strong: 20-40mg.", - "onset": "30-120 minutes.", - "duration": "8-16 hours.", - "after-effects": "1-172 hours.", - "avoid": "All other CNS depressants.", - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming" - ], - "aliases": [ - "nobrium", - "azepamid", - "rudotel", - "raporan", - "mezapam", - "talis" - ], - "dose_to_diazepam": "Medazepam - 10mg ~=10mg Diazepam." - }, - "pretty_name": "Medazepam", - "aliases": [ - "nobrium", - "azepamid", - "rudotel", - "raporan", - "mezapam", - "talis" - ], - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg." - } - }, - "formatted_duration": { - "value": "8-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-120", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-172", - "_unit": "hours" - }, - "id": 473 - }, - "pcp": { - "name": "pcp", - "properties": { - "summary": "A strong dissociative drug. PCP works primarily as an NMDA receptor antagonist. Also referred to as \"wet\" or \"angel dust\". Best known for stories of the strange and sometimes violent behaviour of those under its influence, though it is likely these are only in overdose cases.", - "aliases": [ - "angeldust", - "phencyclidine", - "angel", - "dust", - "angel_dust", - "wet" - ], - "dose": "Oral Light: 2-5mg Common: 5-10mg Strong: 10-15mg+ | Insufflated Light: 2-4mg Common: 4-8mg Strong: 8-15mg+ | NOTE: Be cautious with dosing, this drug is known to cause mania.", - "duration": "4-6 hours", - "after-effects": "12-24 hours", - "onset": "2-20mins", - "categories": [ - "dissociative", - "habit-forming" - ] - }, - "pretty_name": "PCP", - "aliases": [ - "angeldust", - "phencyclidine", - "angel", - "dust", - "angel_dust", - "wet" - ], - "categories": [ - "dissociative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "2-5mg", - "Common": "5-10mg", - "Strong": "10-15mg+" - }, - "Insufflated": { - "Light": "2-4mg", - "Common": "4-8mg", - "Strong": "8-15mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "2-20mins" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_PCP.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Psychosis": "https://psychonautwiki.org/wiki/Psychosis", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection", - "Visual sliding": "https://psychonautwiki.org/wiki/Visual_sliding" - }, - "formatted_aftereffects": { - "value": "12-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Be cautious with dosing, this drug is known to cause mania.", - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Unsafe", - "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner." - }, - "nbomes": { - "status": "Low Risk & Synergy" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Dangerous" - }, - "amt": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Dangerous" - }, - "cannabis": { - "status": "Low Risk & Synergy" - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Caution", - "note": "There are no reports available about this combination" - }, - "dxm": { - "status": "Dangerous" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Unsafe", - "note": "This combination can easily lead to hypermanic states" - }, - "mdma": { - "status": "Unsafe", - "note": "This combination can easily lead to hypermanic states" - }, - "cocaine": { - "status": "Unsafe", - "note": "This combination can easily lead to hypermanic states" - }, - "caffeine": { - "status": "Caution", - "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner." - }, - "alcohol": { - "status": "Unsafe", - "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner." - }, - "ghb/gbl": { - "status": "Dangerous", - "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner." - }, - "opioids": { - "status": "Caution", - "note": "PCP can reduce opioid tolerance, increasing the risk of overdose" - }, - "tramadol": { - "status": "Dangerous" - }, - "benzodiazepines": { - "status": "Unsafe", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely" - }, - "benzos": { - "status": "Unsafe", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely" - }, - "maois": { - "status": "Dangerous", - "note": "This combination is very poorly explored" - }, - "ssris": { - "status": "Unsafe", - "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner." - } - }, - "id": 474 - }, - "c30-nbome": { - "name": "c30-nbome", - "properties": { - "summary": "Inactive, if you do feel effects from \"C30-NBOMe\" you're either having the placebo effect of the world, or are being sold something else, and I recommend you send it in for testing somewhere.", - "categories": [ - "research-chemical", - "inactive" - ] - }, - "pretty_name": "C30-NBOMe", - "categories": [ - "research-chemical", - "inactive" - ], - "id": 475 - }, - "sufentanil": { - "name": "sufentanil", - "properties": { - "summary": "An synthetic analgesic drug that is roughly between 5-10x the potency of it's parent drug, (Fentanyl); It's use is very contained to surgery and post-operative pain.", - "onset": "1-2 minutes.", - "duration": "5-10 minutes.", - "categories": [ - "opioid", - "depressant", - "habit-forming" - ], - "dose": "Light: 1-5ug Common: 5-10ug Strong: 10-25ug.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Sufentanil", - "categories": [ - "opioid", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "1-5ug", - "Common": "5-10ug", - "Strong": "10-25ug." - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "1-2", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 476 - }, - "clonazolam": { - "name": "clonazolam", - "properties": { - "onset": "10-30 minutes", - "duration": "6-10 hours.", - "dose": "Threshold: 50-75ug Light: 75-200ug Common: 200-400ug Heavy: 500-1000ug", - "avoid": "All other CNS depressants.", - "summary": "A long lasting benzodiazepine with heavily hypnotic effects. The safety profile is not well established, and there have been reports that people taking it three days in a row have had a seizure. Most comparable to Triazolam, but with a much longer half-life.", - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant", - "common" - ], - "aliases": [ - "c-lam", - "clam" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Clonazolam", - "aliases": [ - "c-lam", - "clam" - ], - "categories": [ - "benzodiazepine", - "research-chemical", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Threshold": "50-75ug", - "Light": "75-200ug", - "Common": "200-400ug", - "Heavy": "500-1000ug" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Clonazolam.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 477 - }, - "phenmetrazine": { - "name": "phenmetrazine", - "properties": { - "duration": "4-8 hours. More or less dependent on stomach contents and metabolism.", - "aliases": [ - "preludin" - ], - "summary": "Stimulant drug that was previously used as an appetite suppresant, has been withdrawn from the market, due to concerns of abuse and addiction. Usually produces less nervousness, euphoria, and insomnia than drugs of the amphetamine family. Also as a study concluded, it is slightly more effective than dextroamphetamine as a weight loss agent.", - "dose": "Common: 25-50mg Dangerous: 80mg+", - "onset": "15-30 minutes.", - "categories": [ - "stimulant", - "habit-forming" - ], - "after-effects": "1-12 hours." - }, - "pretty_name": "Phenmetrazine", - "aliases": [ - "preludin" - ], - "categories": [ - "stimulant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Common": "25-50mg", - "Dangerous": "80mg+" - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 478 - }, - "2-chloro-ephenidine": { - "name": "2-chloro-ephenidine", - "properties": { - "summary": "Analogue of Ephenidine. Very little is known about this quite obscure compound. Very likely to exhibit dissociative effects, and is slightly less potent than the parent drug Ephenidine.", - "dose": "Oral Light: 100-130mg Common: 130-175mg Strong: 175-200mg Heavy: 200mg+", - "categories": [ - "dissociative", - "research-chemical", - "tentative" - ], - "onset": "10-30 minutes", - "duration": "3-6 hours", - "after-effects": "1-6 hours.", - "aliases": [ - "2-chloroephenidine", - "2chloroephenidine", - "2-cl-ephenidine", - "2clephenidine" - ] - }, - "pretty_name": "2-Chloroephenidine", - "aliases": [ - "2-chloroephenidine", - "2chloroephenidine", - "2-cl-ephenidine", - "2clephenidine" - ], - "categories": [ - "dissociative", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "100-130mg", - "Common": "130-175mg", - "Strong": "175-200mg", - "Heavy": "200mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 479 - }, - "acryl-fentanyl": { - "name": "acryl-fentanyl", - "properties": { - "summary": "A rare opioid and fentanyl analogue (not to be confused with acetyl-fentanyl), this drug is a powerful and potent analgesic. Little reliable information exists, even for basic usage such as dosage. Exercise extreme caution. Overdose may result in respiratory depression. Do not mix with depressants or stimulants. Potentially neurotoxic and carcinogenic.", - "dose": "Light: 5-12.5ug Common: 12.5-25ug Strong: 25.47.5ug+ | Note: Please exercise extreme caution with this substance.", - "duration": "3-5 hours.", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "onset": "10-45 minutes.", - "after-effects": "1-16 hours." - }, - "pretty_name": "Acrylfentanyl", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Light:": { - "Light": "5-12.5ug", - "Common": "12.5-25ug", - "Strong": "25.47.5ug+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "dose_note": " Note: Please exercise extreme caution with this substance.", - "id": 480 - }, - "1,4-butanediol": { - "name": "1,4-butanediol", - "properties": { - "aliases": [ - "bd", - "1,4-bd", - "14bd" - ], - "onset": "10-45 minutes.", - "duration": "3-5 hours", - "avoid": "All other CNS depressants.", - "dose": "Light: 0.5-1ml Common: 1-1.5ml Strong: 1.5ml+", - "summary": "1,4-BD is a clear liquid with intoxicating effects. It is a pro-drug for GHB, and has similar though reportedly inferior effects. It also carries the potential for more health risks than GHB, such as liver toxicity.", - "categories": [ - "depressant", - "habit-forming" - ], - "half-life": "39.3 minutes +/- 11 minutes.", - "after-effects": "2-4 hours", - "test-kits": "Marquis: Faint Brown. | Mandelin: Brown." - }, - "pretty_name": "1,4-Butanediol", - "aliases": [ - "bd", - "1,4-bd", - "14bd" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1ml", - "Common": "1-1.5ml", - "Strong": "1.5ml+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_14Butanediol.shtml" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 481 - }, - "amfecloral": { - "name": "amfecloral", - "properties": { - "summary": "Is a stimulant drug of the Phenethylamine and Amphetamine class. It was used as an appetite suppressant, yet is no longer marketed. It's also interesting that it acts as a prodrug to both Amphetamine and Chloral Hydrate.", - "categories": [ - "stimulant", - "depressant" - ], - "after-effects": "1-12 hours.", - "duration": "5-8 hours.", - "onset": "10-30 minutes." - }, - "pretty_name": "Amfecloral", - "categories": [ - "stimulant", - "depressant" - ], - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 482 - }, - "ashwagandha": { - "name": "ashwagandha", - "properties": { - "summary": "Is an Adaptogen. It is commonly used for its ability to prevent anxiety. It also is helpful in relieving insomnia. It's name means \"Smell of Horse\" due to its smell and the traditional belief that ingesting the this herb will give you the strength and virility of a horse.", - "onset": "15-60 minutes.", - "duration": "6-12 hours.", - "dose": "Light: 300-500 Common: 500-1000 Strong: 1000-2000", - "categories": [ - "depressant", - "supplement", - "common" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Ashwagandha", - "categories": [ - "depressant", - "supplement", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "300-500", - "Common": "500-1000", - "Strong": "1000-2000" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-60", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 483 - }, - "dxm": { - "name": "dxm", - "properties": { - "dose": "Oral First-Plateau: 1.5-2.5mg/kg Second-Plateau: 2.5-7.5mg/kg Third-Plateau: 7.5-15mg/kg Fourth: 15-20mg/kg | NOTE: See http://dxm.tripsit.me for mg/lb doses, among other things. Deaths have been reported at 25mg/kg", - "summary": "Commonly found in certain over the counter cough medicines. Has dissociative effects similar to ketamine or MXE, though also shares properties with opioids and alcohol. Make sure DXM is the only active ingredient in the preparation.", - "aliases": [ - "dextromethorphan", - "robo", - "syrup", - "robotussin", - "dex", - "robitussin" - ], - "onset": "20-60 minutes", - "duration": "6-8 hours", - "calculator": "http://dxm.tripsit.me", - "categories": [ - "dissociative", - "habit-forming", - "common" - ], - "chart": "http://taimapedia.org/images/4/46/DXMDosingChart.png", - "after-effects": "1-12 hours." - }, - "pretty_name": "DXM", - "aliases": [ - "dextromethorphan", - "robo", - "syrup", - "robotussin", - "dex", - "robitussin" - ], - "categories": [ - "dissociative", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "First-Plateau": "1.5-2.5mg/kg", - "Second-Plateau": "2.5-7.5mg/kg", - "Third-Plateau": "7.5-15mg/kg", - "Fourth": "15-20mg/kg" - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_DXM.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection", - "Visual sliding": "https://psychonautwiki.org/wiki/Visual_sliding" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: See http://dxm.tripsit.me for mg/lb doses, among other things. Deaths have been reported at 25mg/kg", - "sources": { - "_general": [ - "Dextromethorphan and its metabolite dextrorphan block alpha3beta4 neuronal nicotinic receptors. - http://www.ncbi.nlm.nih.gov/pubmed/10869398", - "Dextromethorphan potentiates the antinociceptive effects of morphine and the delta-opioid agonist SNC80 in squirrel monkeys. - http://www.ncbi.nlm.nih.gov/pubmed/11805202", - "Dextromethorphan psychosis, dependence and physical withdrawal. - http://www.ncbi.nlm.nih.gov/pubmed/16318953", - "Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice. - http://www.ncbi.nlm.nih.gov/pubmed/18819620", - "Dextromethorphan as a potential rapid-acting antidepressant. - http://www.ncbi.nlm.nih.gov/pubmed/21367535", - "The treatment of heroin addicts with dextromethorphan: a double-blind comparison of dextromethorphan with chlorpromazine. - http://www.ncbi.nlm.nih.gov/pubmed/2187002", - "High doses of dextromethorphan, an NMDA antagonist, produce effects similar to classic hallucinogens. - http://www.ncbi.nlm.nih.gov/pubmed/22526529", - "Lack of efficacy of dextromethorphan in managing alcohol withdrawal: a preliminary report of a randomized, double-blind, placebo-controlled trial. - http://www.ncbi.nlm.nih.gov/pubmed/24346753" - ] - }, - "combos": { - "mushrooms": { - "status": "Low Risk & Synergy" - }, - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Unsafe", - "note": "The DOx class as psychedelic stimulants have the potential to mask the effects of DXM and could lead to redosing to an unsafe level. DXM can also potentiate DOx resulting in an unpleasantly intense experience." - }, - "nbomes": { - "status": "Unsafe" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Unsafe" - }, - "amt": { - "status": "Dangerous" - }, - "5-meo-xxt": { - "status": "Unsafe", - "note": "Little information exists about this combination." - }, - "cannabis": { - "status": "Low Risk & Synergy" - }, - "ketamine": { - "status": "Low Risk & No Synergy" - }, - "mxe": { - "status": "Low Risk & No Synergy" - }, - "pcp": { - "status": "Dangerous" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Unsafe", - "note": "Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues." - }, - "mdma": { - "status": "Dangerous" - }, - "cocaine": { - "status": "Unsafe", - "note": "Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues" - }, - "caffeine": { - "status": "Low Risk & No Synergy", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort." - }, - "alcohol": { - "status": "Dangerous", - "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Additionally CNS depression can lead to difficulty breathing. Avoid on anything higher than 1st plateau." - }, - "ghb/gbl": { - "status": "Dangerous", - "note": "Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the patient falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. This combination is hard to predict" - }, - "opioids": { - "status": "Dangerous", - "note": "CNS depression, difficult breathing, heart issues, hepatoxic, just very unsafe combination all around. Additionally if one takes dxm, their tolerance of opiates goes down slightly, thus causing additional synergistic effects." - }, - "tramadol": { - "status": "Dangerous" - }, - "benzodiazepines": { - "status": "Caution", - "note": "Small doses of benzos can end a bad trip, but both substances potentiate the ataxia and sedation caused by the other and this can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position." - }, - "benzos": { - "status": "Caution", - "note": "Small doses of benzos can end a bad trip, but both substances potentiate the ataxia and sedation caused by the other and this can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position." - }, - "maois": { - "status": "Dangerous", - "note": "High risk of serotonin syndrome" - }, - "ssris": { - "status": "Dangerous", - "note": "High risk of serotonin syndrome." - } - }, - "id": 484 - }, - "carphedon": { - "name": "carphedon", - "properties": { - "summary": "A nootropic and piracetam analogue also known as fonturacetam, this drug has been shown to have potential memory enhancing, anxiolytic, anti-amnesia and anti-depressive effects, however has little recreational value. Around 45x more potent than Piracetam.", - "aliases": [ - "phenylpiracetam", - "phenotropil" - ], - "onset": "Rapid.", - "duration": "4-6 hours.", - "dose": "Oral Common: 100-200mg | NOTE: Typically taken up to three times a day.", - "categories": [ - "stimulant", - "research-chemical", - "nootropic" - ], - "after-effects": "1-4 hours." - }, - "pretty_name": "Phenylpiracetam", - "aliases": [ - "phenylpiracetam", - "phenotropil" - ], - "categories": [ - "stimulant", - "research-chemical", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Common": "100-200mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Rapid." - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "dose_note": " NOTE: Typically taken up to three times a day.", - "id": 485 - }, - "4-mec": { - "name": "4-mec", - "properties": { - "summary": "A substituted cathinone stimulant; little is known about its safety or subjective effects. It is believed to have similar effects to mephedrone, but with a lower potency and a stronger stimulating character.", - "aliases": [ - "4-Methylethcathinone", - "4mec", - "4-methylethcathinone" - ], - "dose": "Oral Light: 50-100mg Common: 100-200mg Strong: 200mg+ | Insufflated Light: 25-40mg Common: 40-100mg Strong: 100-150mg+", - "onset": "Oral: 15-45 minutes. Insufflated 3-5 minutes.", - "duration": "Oral: 2-5 hours. Insufflated 2-3 hours.", - "after-effects": "2-4 hours.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness." - }, - "pretty_name": "4-MEC", - "aliases": [ - "4-Methylethcathinone", - "4mec", - "4-methylethcathinone" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-200mg", - "Strong": "200mg+" - }, - "Insufflated": { - "Light": "25-40mg", - "Common": "40-100mg", - "Strong": "100-150mg+" - } - }, - "formatted_duration": { - "Oral": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4Methylethcathinone.shtml" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "id": 486 - }, - "naproxen": { - "name": "naproxen", - "properties": { - "summary": "A very common pain reliever/fever reducer also known as Aleve. Naproxen is in the same category as Ibuprofen, which is also a nonsteroidal anti-inflammatory. This drug is available in most places over the counter. Is sometimes used to reduce the body-load of certain drugs.", - "onset": "1 hour.", - "duration": "4-6 hours. ER forumulations up to 12 hours.", - "dose": "Common: 250-500mg | Note: Maximum recommended daily dose is 1500mg.", - "avoid": "Alcoholic beverages.", - "categories": [ - "common" - ] - }, - "pretty_name": "Naproxen", - "categories": [ - "common" - ], - "formatted_dose": { - "Common:": { - "Common": "250-500mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Naproxen.shtml" - }, - "dose_note": " Note: Maximum recommended daily dose is 1500mg.", - "id": 487 - }, - "mdai": { - "name": "mdai", - "properties": { - "summary": "A selective serotonin releasing agent which is rarely used without a stimulant to obtain desirable effects. Previously believed not to be neuruotoxic, however MDAI has been implicated in several lethal and non-lethal intoxications, and as such may pose more of a risk to health than previously believed.", - "dose": "Threshold: 20-40mg Light: 40-100mg Common: 100-150mg Heavy: 150-300mg+", - "onset": "30-60 minutes", - "duration": "4-6 hours.", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "MDAI", - "categories": [ - "psychedelic", - "stimulant", - "research-chemical", - "habit-forming", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Threshold": "20-40mg", - "Light": "40-100mg", - "Common": "100-150mg", - "Heavy": "150-300mg+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-60", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MDAI.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 488 - }, - "1p-eth-lad": { - "name": "1p-eth-lad", - "properties": { - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "dose": "Oral Threshold: 20-30ug Light: 30-60ug Common: 60-100ug Strong: 100-200ug+ | NOTE: These doses are very tentative, and are based on the likelihood that the dosage profile will be similar to ETH-LAD.", - "onset": "15-90 minutes", - "duration": "6-10 hours.", - "summary": "A new psychedelic lysergamide which is suspected to be a prodrug of ETH-LAD, which could explain why the doses are very similar. Or it could be active on its own. Scientific studies would need to be written to understand, yet there are none.", - "aliases": [ - "1pethlad" - ], - "after-effects": "2-12 hours.", - "experiences": "https://erowid.org/experiences/subs/exp_1PETHLAD.shtml" - }, - "pretty_name": "1P-ETH-LAD", - "aliases": [ - "1pethlad" - ], - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "20-30ug", - "Light": "30-60ug", - "Common": "60-100ug", - "Strong": "100-200ug+" - } - }, - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "dose_note": " NOTE: These doses are very tentative, and are based on the likelihood that the dosage profile will be similar to ETH-LAD.", - "id": 489 - }, - "diphenidine": { - "name": "diphenidine", - "properties": { - "summary": "A dissociative anaesthetic related to ephenidine with similar qualities to PCP and ketamine. Has seen some popularity as a recreational RC. Dosage curve has been reported as particularly steep, so care should be taken.", - "dose": "Oral Threshold: 50mg Light: 70-85mg Common: 85-110mg Heavy: 110-150mg | NOTE: Diphenidine is an extremely new substance with very little record of human use. Start low, work your way up.", - "onset": "15-30 minutes", - "duration": "4-6 hours", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "after-effects": "4-24 hours", - "aliases": [ - "dpd" - ] - }, - "pretty_name": "Diphenidine", - "aliases": [ - "dpd" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "50mg", - "Light": "70-85mg", - "Common": "85-110mg", - "Heavy": "110-150mg" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Diphenidine.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Auditory suppression": "https://psychonautwiki.org/wiki/Auditory_suppression", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Consciousness disconnection": "https://psychonautwiki.org/wiki/Consciousness_disconnection", - "Depersonalization": "https://psychonautwiki.org/wiki/Depersonalization", - "Derealization": "https://psychonautwiki.org/wiki/Derealization", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Environmental cubism": "https://psychonautwiki.org/wiki/Environmental_cubism", - "Environmental orbism": "https://psychonautwiki.org/wiki/Environmental_orbism", - "Frame rate suppression": "https://psychonautwiki.org/wiki/Frame_rate_suppression", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of decreased weight": "https://psychonautwiki.org/wiki/Perception_of_decreased_weight", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Perspective distortions": "https://psychonautwiki.org/wiki/Perspective_distortions", - "Physical autonomy": "https://psychonautwiki.org/wiki/Physical_autonomy", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile disconnection": "https://psychonautwiki.org/wiki/Tactile_disconnection", - "Tactile suppression": "https://psychonautwiki.org/wiki/Tactile_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection" - }, - "formatted_aftereffects": { - "value": "4-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Diphenidine is an extremely new substance with very little record of human use. Start low, work your way up.", - "id": 490 - }, - "am-2201": { - "name": "am-2201", - "properties": { - "summary": "A synthetic cannabanoid that is very potent. Active doses start at around 250ug's. Please be cautious with this substance. It has also been noted that it can cause convulsions.", - "dose": "Vapourized Light: 250-500ug Common: 500-1000ug Strong: 1000-2000ug", - "onset": "Vapourized: 1-3 minutes. | Oral: 15-30 minutes.", - "duration": "Vapourized: 30-90 minutes. | Oral: 60-180 minutes.", - "aliases": [ - "am2201" - ], - "after-effects": "15-60 minutes.", - "categories": [ - "research-chemical", - "tentative", - "habit-forming" - ] - }, - "pretty_name": "AM-2201", - "aliases": [ - "am2201" - ], - "categories": [ - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Vapourized": { - "Light": "250-500ug", - "Common": "500-1000ug", - "Strong": "1000-2000ug" - } - }, - "formatted_duration": { - "Vapourized": "30-90", - "Oral": "60-180", - "_unit": "minutes" - }, - "formatted_onset": { - "Vapourized": "1-3", - "Oral": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "15-60", - "_unit": "minutes" - }, - "id": 491 - }, - "pregabalin": { - "name": "pregabalin", - "properties": { - "summary": "Pregabalin (Lyrica) is a GABA derivative that is used to treat neuropathic pain and seizures, as well as anxiety.", - "duration": "6-14 hours (dependant on dose)", - "dose": "Light: 150-300mg Common: 300-600mg Strong: 600-900mg", - "onset": "90-150 minutes.", - "aliases": [ - "lyrica", - "pregablin" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "pregabalin": "(Lyrica) is a GABA derivative that is used to treat neuropathic pain and seizures, as well as anxiety. It is sometimes used recreationally, however an unusual tolerance profile renders it ineffective with regular use.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Pregabalin", - "aliases": [ - "lyrica", - "pregablin" - ], - "categories": [ - "depressant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "150-300mg", - "Common": "300-600mg", - "Strong": "600-900mg" - } - }, - "formatted_duration": { - "value": "6-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "90-150", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Seizure suppression": "https://psychonautwiki.org/wiki/Seizure_suppression", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " Note \u0004e", - "sources": { - "_general": [ - "Pregabalin reduces cocaine self-administration and relapse to cocaine seeking in the rat - http://www.ncbi.nlm.nih.gov/pubmed/22734646" - ] - }, - "id": 492 - }, - "ab-chminaca": { - "name": "ab-chminaca", - "properties": { - "summary": "A synthetic cannabinoid related to AB-FUBINACA which has had some mild popularity. There have been reports of death in overdose, similar to AB-FUBINACA and it has a low threshold dose. Exercise caution.", - "duration": "Vaporized: 1-2 hours | Oral: 5-12 hours", - "dose": "Light: 50-100µg Common: 100-250µg Strong: 250-400µg Heavy: 400µg+", - "categories": [ - "research-chemical", - "habit-forming", - "tentative" - ], - "onset": "Vaporized: 1-5 minutes | Oral: 20-80 minutes", - "after-effects": "Vapourized: 2-4 hours. | Oral: 5-12 hours." - }, - "pretty_name": "AB-CHMINACA", - "categories": [ - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100µg", - "Common": "100-250µg", - "Strong": "250-400µg", - "Heavy": "400µg+" - } - }, - "formatted_duration": { - "Vaporized": "1-2", - "Oral": "5-12", - "_unit": "hours" - }, - "formatted_onset": { - "Vaporized": "1-5", - "Oral": "20-80", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Vapourized": "2-4", - "Oral": "5-12", - "_unit": "hours" - }, - "id": 493 - }, - "clomethiazole": { - "name": "clomethiazole", - "properties": { - "an": "", - "summary": "Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal.", - "onset": "15-40 minutes. ", - "duration": "5-8 hours. ", - "dose": "Oral Threshold: 100mg Light: 100-150mg Common: 150-200mg Heavy: 200mg+", - "warning": "The normal amount in capsules is 192mg's. Treat this more as a barbiturate than a benzodiazepine, as the toxicology for this substance is rather lacking.", - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "tentative" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "after-effects": "1-16 hours." - }, - "pretty_name": "Clomethiazole", - "categories": [ - "depressant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "100mg", - "Light": "100-150mg", - "Common": "150-200mg", - "Heavy": "200mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "id": 494 - }, - "sertraline": { - "name": "sertraline", - "properties": { - "categories": [ - "ssri" - ], - "aliases": [ - "zoloft", - "lustral" - ] - }, - "pretty_name": "Sertraline", - "aliases": [ - "zoloft", - "lustral" - ], - "categories": [ - "ssri" - ], - "id": 495 - }, - "glaucine": { - "name": "glaucine", - "properties": { - "summary": "An alkaloid that is found in several different scpecies in the Papaveraceae family. It has antiinflammatory and antitussive effects. Can also be referred to as Yellow Horned Poppy.", - "dose": "Oral Light: 50-100mg Common: 100-150mg Strong: 150-200mg+", - "onset": "45-90 minutes.", - "duration": "6-8 hours.", - "after-effects": "1-8 hours.", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "tentative" - ] - }, - "pretty_name": "Glaucine", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-150mg", - "Strong": "150-200mg+" - } - }, - "formatted_duration": { - "value": "6-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 496 - }, - "viagra": { - "name": "viagra", - "properties": { - "summary": "A medication originally developed to lower blood pressure, and now widely used to treat erectile dysfunction in men. Do not mix with anything that lowers blood pressure. Contact EMS if erection lasts longer than 4 hours.", - "dose": "Light: 25-30mg Common: 30-50mg Strong: 50-100mg.", - "duration": "3-6 hours.", - "onset": "10-60 minutes." - }, - "pretty_name": "Sildenafil", - "formatted_dose": { - "Oral": { - "Light": "25-30mg", - "Common": "30-50mg", - "Strong": "50-100mg." - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-60", - "_unit": "minutes" - }, - "id": 497 - }, - "25i-nboh": { - "name": "25i-nboh", - "properties": { - "summary": "A phenethylamine psychedelic and stimulant derivative of 2C-I, this compound is related and has similar effects to 25i-NBOMe. It is significantly more potent than 2C-I but less potent than 25i-NBOMe. Overdoses of NBOH compounds may cause dangerous vasoconstriction. May induce uncomfortable body load.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "onset": "20-40 minutes", - "duration": "5-10 hours.", - "dose": "Threshold: 166ug-416ug Light: 416ug-766ug Common: 800-1400ug Strong: 1400ug-2000ug+", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "aliases": [ - "nboh-2ci", - "cimbi-27" - ], - "after-effects": "1-12 hours.", - "avoid": "Other psychedelics, stimulants, and double dosing." - }, - "pretty_name": "25I-NBOH", - "aliases": [ - "nboh-2ci", - "cimbi-27" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "166ug-416ug", - "Light": "416ug-766ug", - "Common": "800-1400ug", - "Strong": "1400ug-2000ug+" - } - }, - "formatted_duration": { - "value": "5-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_25INBOH.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 498 - }, - "isomethadone": { - "name": "isomethadone", - "properties": { - "summary": "Once a pharmaceutical drug also known as isoamidone, this opioid analgesic and methadone analogue was withdrawn from the market and is seldom seen today. Rarely abused, though reports state it is around twice as potent as methadone, and more euphoric.", - "categories": [ - "opioid", - "habit-forming", - "tentative", - "depressant" - ], - "dose": "Light: 1.5-2.5mg Common: 2.5-7.5mg Strong: 7.5-15mg", - "onset": "30-90 minutes", - "duration": "30-40 hours", - "avoid": "All other CNS depressants", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-24 hours." - }, - "pretty_name": "Isomethadone", - "categories": [ - "opioid", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "1.5-2.5mg", - "Common": "2.5-7.5mg", - "Strong": "7.5-15mg" - } - }, - "formatted_duration": { - "value": "30-40", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 499 - }, - "neb": { - "name": "neb", - "properties": { - "summary": "N-Ethylbuphedrone, an uncommon substituted cathinone. First appeared around 2011 but has not become popular. Effects should somewhat resemble other cathinones generally. Short-acting stimulating with more dopamine action than serotonin.", - "aliases": [ - "n-ethylbuphedrone" - ], - "duration": "Oral: 90-180 minutes. | Insufflated: 90-120 minutes.", - "dose": "Oral Threshold: 30mg Light: 30-50mg Common: 50-80mg Strong: 80-100mg+ | Insufflated Light: 10-15mg Common: 15-30mg Strong: 30-45mg", - "onset": "Oral: 20-30 minutes | Insufflated: 5-10 minutes.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "NEB", - "aliases": [ - "n-ethylbuphedrone" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "30mg", - "Light": "30-50mg", - "Common": "50-80mg", - "Strong": "80-100mg+" - }, - "Insufflated": { - "Light": "10-15mg", - "Common": "15-30mg", - "Strong": "30-45mg" - } - }, - "formatted_duration": { - "Oral": "90-180", - "Insufflated": "90-120", - "_unit": "minutes" - }, - "formatted_onset": { - "Oral": "20-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 500 - }, - "4-methylaminorex": { - "name": "4-methylaminorex", - "properties": { - "summary": "A very potent stimulant that has quite a long duration of action at around 16 hours.", - "onset": "5-15 minutes.", - "duration": "14-18 hours.", - "dose": "Threshold: 1mg Light: 1-5mg Common: 5-10mg Strong: 10-15mg Dangerous: 15-20mg+", - "aliases": [], - "after-effects": "1-24 hours.", - "categories": [ - "stimulant", - "habit-forming", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "4-METHYLAMINOREX", - "aliases": [], - "categories": [ - "stimulant", - "habit-forming", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "1mg", - "Light": "1-5mg", - "Common": "5-10mg", - "Strong": "10-15mg", - "Dangerous": "15-20mg+" - } - }, - "formatted_duration": { - "value": "14-18", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 501 - }, - "hydrocodone": { - "name": "hydrocodone", - "properties": { - "dose": "Oral Light: 5-10mg Common: 10-25mg Strong: 25-40mg.", - "onset": "10-60 minutes depending on stomach contents.", - "avoid": "Alcohol (Can cause dangerous respiratory depression, which may result in death) Grapefruit juice (Inhibits enzymes in your small intestine, increasing absorption rate to a possible dangerous amount)", - "duration": "4-8 hours", - "categories": [ - "depressant", - "opioid", - "habit-forming", - "depressant", - "common" - ], - "summary": "A codeine-derived opioid generally unheard of outside the United States. Generally mild in effects, used as an analgesic and cough-supressant. Sometimes used recreationally.", - "aliases": [ - "vicodin", - "hydro" - ], - "bioavailability": "Oral 70-85%", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Hydrocodone", - "aliases": [ - "vicodin", - "hydro" - ], - "categories": [ - "depressant", - "opioid", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-25mg", - "Strong": "25-40mg." - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Hydrocodone.shtml" - }, - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 502 - }, - "dipipanone": { - "name": "dipipanone", - "properties": { - "summary": "A powerful opioid of equivalent strength to morphine, rarely seen outside of medical environments. Often used to treat severe pain where morphine is contraindicated. Usually found in combination with the antihistamine Cyclizine, which potentiates it.", - "dose": "Light: 3-5mg Common: 5-10mg Strong: 10-20mg+", - "onset": "Oral: 15-30 minutes | Insufflated: 5-15 minutes. | Intravenous: 0-1 minutes", - "duration": "3-6 hours.", - "aliases": [ - "diconal" - ], - "avoid": "All other CNS depressants", - "categories": [ - "opioid", - "depressant", - "habit-forming", - "depressant" - ], - "warning": "If you do come across these pills, and IV them, you will reach a point where the Cyclizine in the Diconal preparation will reach a very bad result, and missed shots can end up with amputations.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Dipipanone", - "aliases": [ - "diconal" - ], - "categories": [ - "opioid", - "depressant", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "3-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-15", - "Intravenous": "0-1", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 503 - }, - "4-ho-dpt": { - "name": "4-ho-dpt", - "properties": { - "summary": "A psychedelic hallucinogenic first synthesized by alexander shulgin. At light doses it causes enhanced cognition and appreciation for things like art and music while high doses cause visuals. The drug is known to cause a bodyload.", - "dose": "Light: 25-50mg Moderate: 50-75mg Strong: 75-100mg Heavy: 100mg +", - "duration": "Insufflated: 2-4 hours.", - "onset": "Insufflated: 10-20 minutes.", - "aliases": [ - "4hodpt", - "4-hydroxy-n", - "n-dipropyltryptamine" - ], - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ] - }, - "pretty_name": "4-HO-DPT", - "aliases": [ - "4hodpt", - "4-hydroxy-n", - "n-dipropyltryptamine" - ], - "categories": [ - "tentative", - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50mg", - "Moderate": "50-75mg", - "Strong": "75-100mg", - "Heavy": "100mg" - } - }, - "formatted_duration": { - "Insufflated": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "10-20", - "_unit": "minutes" - }, - "id": 504 - }, - "ibogaine": { - "name": "ibogaine", - "properties": { - "summary": "An alkaloid found in many African plants most famously Iboga, with psychedelic and hallucinogenic properties. May be unpleasant. Traditionally used in tribal environments for coming-of-age rituals, it has recently been used as an alternative treatment for drug addiction although this usage has not been backed by conclusive data in humans. Has killed in overdose.", - "aliases": [ - "iboga" - ], - "dose": "Oral Common: 16-22mg/kg NOTE: Doses are for Ibogaine Hcl. Potency of ibogaine root bark can vary from roughly 2.5-6% ibogaine content", - "duration": "24-30 hours", - "onset": "45-180 minutes", - "categories": [ - "psychedelic", - "opioid", - "dissociative", - "depressant" - ], - "after-effects": "24-72 hours", - "effects": "Addiction help, Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil constriction, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Ibogaine", - "aliases": [ - "iboga" - ], - "categories": [ - "psychedelic", - "opioid", - "dissociative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Common": "16-22mg/kg", - "NOTE": "Doses" - } - }, - "formatted_duration": { - "value": "24-30", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-180", - "_unit": "minutes" - }, - "formatted_effects": [ - "Addiction help", - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil constriction", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Ibogaine.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal25.shtml" - }, - "formatted_aftereffects": { - "value": "24-72", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Toxicity of ibogaine is associated with a lengthened QT interval in the electrophysiology of the heart - http://www.nejm.org/doi/full/10.1056/NEJMc0804248#t=article", - "signs of neurotoxicity found in animal testing - http://www.sciencedirect.com/science/article/pii/030645229390500F" - ] - }, - "id": 505 - }, - "metizolam": { - "name": "metizolam", - "properties": { - "summary": "Also known as desmethyletizolam, a thienodiazepine similar in effects and structure to etizolam, but around half as potent and with around a 60% longer half-life. A sedative, and hypnotic, it may cause amnesia and lowered inhibitions in excess.", - "categories": [ - "benzodiazepine", - "research-chemical", - "depressant", - "habit-forming", - "tentative" - ], - "duration": "5-8 hours", - "onset": "30-90 minutes", - "after-effects": "10-30 hours", - "aliases": [ - "metiz", - "desmethyletizolam" - ], - "dose": "Light: 1-2mg Common: 2-4mg Strong: 4-6mg Heavy: 6mg+" - }, - "pretty_name": "Metizolam", - "aliases": [ - "metiz", - "desmethyletizolam" - ], - "categories": [ - "benzodiazepine", - "research-chemical", - "depressant", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "1-2mg", - "Common": "2-4mg", - "Strong": "4-6mg", - "Heavy": "6mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-90", - "_unit": "minutes" - }, - "pweffects": { - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Analysis suppression": "https://psychonautwiki.org/wiki/Analysis_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Disinhibition": "https://psychonautwiki.org/wiki/Disinhibition", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Motor control loss": "https://psychonautwiki.org/wiki/Motor_control_loss", - "Muscle relaxation": "https://psychonautwiki.org/wiki/Muscle_relaxation", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration" - }, - "formatted_aftereffects": { - "value": "10-30", - "_unit": "hours" - }, - "id": 506 - }, - "5-br-dmt": { - "name": "5-br-dmt", - "properties": { - "summary": "Psychedelic drug of the Trypyamine class, and is also found in two marine invertebrates. Animal studies have shown that this could be useful for sedative and/or antidepressant use.", - "onset": "1-2 minutes.", - "duration": "15-90 minutes.", - "dose": "Vapourized Light: 10-25mg. Common: 25-35mg. Strong: 35-65mg.", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ] - }, - "pretty_name": "5-Bromo-DMT", - "categories": [ - "psychedelic", - "tentative", - "research-chemical" - ], - "formatted_dose": { - "Vapourized": { - "Light": "10-25mg.", - "Common": "25-35mg.", - "Strong": "35-65mg." - } - }, - "formatted_duration": { - "value": "15-90", - "_unit": "minutes" - }, - "formatted_onset": { - "value": "1-2", - "_unit": "minutes" - }, - "id": 507 - }, - "ald-52": { - "name": "ald-52", - "properties": { - "summary": "ALD-52, or N-acetyl-LSD is a less common chemical analogue of LSD, first synthesised by Albert Hoffman. It was famously implicated in the 'Orange Sunshine' trial. A psychedelic lysergamide, this compound exhibits similar properties to LSD, and is thought to be a pro-drug for LSD.", - "onset": "45-90 minutes depending on ROA and stomach contents", - "duration": "9-14 hours, varying with dosage (heavy doses can lead to much longer trips)", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "dose": "Light: 25-75ug Common: 75-150ug Strong: 150-300ug.", - "effects": "visual distortions, a sense of childlike wonder, brightening of colors,racing thoughts, hue shifts, euphoria, anxiety, confusion", - "aliases": [ - "ald52", - "1alsd", - "1a-lsd" - ], - "after-effects": "12-24h", - "avoid": "marijuana (can potentiate effects)" - }, - "pretty_name": "ALD-52", - "aliases": [ - "ald52", - "1alsd", - "1a-lsd" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "25-75ug", - "Common": "75-150ug", - "Strong": "150-300ug." - } - }, - "formatted_duration": { - "value": "9-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "45-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "visual distortions", - "a sense of childlike wonder", - "brightening of colors", - "racing thoughts", - "hue shifts", - "euphoria", - "anxiety", - "confusion" - ], - "formatted_aftereffects": { - "value": "12-24h" - }, - "id": 508 - }, - "caffeine": { - "name": "caffeine", - "properties": { - "effects": "elevated heartrate, increase in cognitive abilities, physical agitation, panicked thinking, racing thoughts, uncomfortable bodyload", - "onset": "5-10 minutes", - "summary": "Caffeine is a a CNS stimulant, and also the most widely used psychoactive substance in the world. It is legal and unregulated in most parts of the world, and is found in many commonly sold products. It has a good safety profile, though regular heavy use can cause physical dependence and contribute to certain medical conditions.", - "dose": "Threshold: 10-20mg Light: 20-75mg Common: 75mg-250mg Strong: 250-400mg Heavy: 400mg+ | NOTE: The lethal dose for caffeine starts at approximately 3g. The average cup of coffee contains roughly 75-150mg of caffeine.", - "duration": "1.5-5 hours", - "after-effects": "3-4 hours", - "aliases": [ - "coffee" - ], - "categories": [ - "stimulant", - "habit-forming", - "nootropic", - "common" - ], - "bioavailability": "Orally it varies from around 77%-99%" - }, - "pretty_name": "Caffeine", - "aliases": [ - "coffee" - ], - "categories": [ - "stimulant", - "habit-forming", - "nootropic", - "common" - ], - "formatted_dose": { - "Threshold:": { - "Threshold": "10-20mg", - "Light": "20-75mg", - "Common": "75mg-250mg", - "Strong": "250-400mg", - "Heavy": "400mg+" - } - }, - "formatted_duration": { - "value": "1.5-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "elevated heartrate", - "increase in cognitive abilities", - "physical agitation", - "panicked thinking", - "racing thoughts", - "uncomfortable bodyload" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Caffeine.shtml" - }, - "pweffects": { - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Bronchodilation": "https://psychonautwiki.org/wiki/Bronchodilation", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "3-4", - "_unit": "hours" - }, - "dose_note": " NOTE: The lethal dose for caffeine starts at approximately 3g. The average cup of coffee contains roughly 75-150mg of caffeine.", - "combos": { - "mushrooms": { - "status": "Low Risk & No Synergy" - }, - "lsd": { - "status": "Low Risk & No Synergy" - }, - "dmt": { - "status": "Low Risk & No Synergy" - }, - "mescaline": { - "status": "Low Risk & No Synergy", - "note": "High doses of caffeine are uncomfortable and this will be magnified by psychedelics" - }, - "dox": { - "status": "Caution", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating it may cause some physical discomfort." - }, - "nbomes": { - "status": "Caution", - "note": "Caffiene can bring out the natural stimulation from psychedelic drugs to make it uncomfortable. High doses can cause anxiety which is hard to handle while tripping" - }, - "2c-x": { - "status": "Low Risk & No Synergy", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort." - }, - "2c-t-x": { - "status": "Low Risk & No Synergy", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort." - }, - "amt": { - "status": "Caution", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort." - }, - "5-meo-xxt": { - "status": "Low Risk & No Synergy", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort." - }, - "cannabis": { - "status": "Low Risk & No Synergy" - }, - "ketamine": { - "status": "Low Risk & No Synergy", - "note": "No unexpected interactions." - }, - "mxe": { - "status": "Low Risk & No Synergy", - "note": "No likely interactions" - }, - "dxm": { - "status": "Low Risk & No Synergy", - "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort." - }, - "pcp": { - "status": "Caution", - "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner." - }, - "nitrous": { - "status": "Low Risk & No Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "This combination of stimulants is not generally necessary and may increase strain on the heart, as well as potentially causing anxiety and greater physical discomfort." - }, - "mdma": { - "status": "Caution", - "note": "Caffiene is not really necessary with MDMA and increases any neurotoxic effects from MDMA" - }, - "cocaine": { - "status": "Caution", - "note": "Both stimulants, risk of tachycardia, hypertension, and in extreme cases heart failure." - }, - "alcohol": { - "status": "Low Risk & No Synergy" - }, - "ghb/gbl": { - "status": "Low Risk & No Synergy" - }, - "opioids": { - "status": "Low Risk & No Synergy" - }, - "tramadol": { - "status": "Low Risk & No Synergy" - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Low Risk & No Synergy" - }, - "ssris": { - "status": "Low Risk & No Synergy" - } - }, - "id": 509 - }, - "bk-2c-i": { - "name": "bk-2c-i", - "properties": { - "summary": "Novel psychedelic that is the Beta-Ketone derivative of 2C-I.", - "Duration": "4-6 hours.", - "dose": "Oral Light: 100-120mg Common: 120-180mg Strong: 180-250mg Heavy: 250mg+", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "warn": "If you have thyroid problems, do not take this substance.", - "Onset": "20-40 minutes.", - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "βk-2C-I", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "100-120mg", - "Common": "120-180mg", - "Strong": "180-250mg", - "Heavy": "250mg+" - } - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "id": 510 - }, - "clorazepate": { - "name": "clorazepate", - "properties": { - "summary": "Is a prodrug for Desmethyldiazepam which is responsible for most of the therapeutic effects. Has a long half life, with the addition of Desmethyldiazepam as the main metabolite, which makes it much longer.", - "dose": "Low: 5-10mg Common: 10-20mg Strong: 20-40mg+", - "onset": "20-80 minutes.", - "duration": "8-12 hours.", - "avoid": "All other CNS depressants.", - "aliases": [ - "tranxene", - "novo-clopate", - "tranzene" - ], - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming", - "depressant" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "bioavailability": "Oral: 91%.", - "after-effects": "1-8 hours.", - "dose_to_diazepam": "Clorazepate - 15mg ~=10mg Diazepam." - }, - "pretty_name": "Clorazepate", - "aliases": [ - "tranxene", - "novo-clopate", - "tranzene" - ], - "categories": [ - "depressant", - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Low": "5-10mg", - "Common": "10-20mg", - "Strong": "20-40mg+" - } - }, - "formatted_duration": { - "value": "8-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-80", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Bentazepam versus Clorazepate in the treatment of anxiety disorders. http://www.sciencedirect.com/science/article/pii/S0011393X05804357" - ] - }, - "id": 511 - }, - "4-mta": { - "name": "4-mta", - "properties": { - "summary": "Empathogen with very low chronic toxicity but high risk of acute harm due to mixed serotonin release and MAOI action. Reported to lack euphoria and rarely sold since being scheduled.", - "categories": [ - "research-chemical", - "empathogen", - "tentative" - ], - "aliases": [ - "4-methylthioamphetamine" - ] - }, - "pretty_name": "4-MTA", - "aliases": [ - "4-methylthioamphetamine" - ], - "categories": [ - "research-chemical", - "empathogen", - "tentative" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4MTA.shtml" - }, - "id": 512 - }, - "hot-7": { - "name": "hot-7", - "properties": { - "summary": "A rather rare psychedelic phenylethylamine that is the hydroxylated version and prodrug for 2C-T-7.", - "onset": "60-180 minutes.", - "duration": "5-8 hours", - "dose": "Oral Threshold: 15mg Light: 15-20mg Common: 20-30mg Strong: 30-40mg+ | NOTE: Start low as there is a weird dose curve with this substance, and there also could be possible MAOI effect just like with 2C-T-7.", - "aliases": [ - "hot7" - ], - "after-effects": "1-12 hours.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative", - "empathogen" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "a": "rather rare psychedelic phentlethylamine that is the hydroxlated version and prodrug for 2C-T-7. It decomposes into the parent compound." - }, - "pretty_name": "HOT-7", - "aliases": [ - "hot7" - ], - "categories": [ - "psychedelic", - "research-chemical", - "tentative", - "empathogen" - ], - "formatted_dose": { - "Oral": { - "Threshold": "15mg", - "Light": "15-20mg", - "Common": "20-30mg", - "Strong": "30-40mg+" - } - }, - "formatted_duration": { - "value": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-180", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Start low as there is a weird dose curve with this substance, and there also could be possible MAOI effect just like with 2C-T-7.", - "id": 513 - }, - "heroin": { - "name": "heroin", - "properties": { - "dose": "Insufflated Light: 7.5-20mg Common: 20-35mg Strong: 35-50mg Heavy: 50-75mg | Smoked Light: 5-15mg Common: 15-25mg Strong 20-30mg Heavy: 30-50mg | Intravenous Common: 5-10mg Strong: 8-15mg | Note: Heroin dose varies greatly depending on quality and tolerance.", - "onset": "Insufflated: 10-15 minutes | Smoked: 5-10 minutes | IV: 0-5 minutes", - "duration": "Insufflated: 3-6 hours | IV: 4-5 hours | Smoked: 3-5 hours.", - "aliases": [ - "diamorphine" - ], - "marquis": "Deep purplish red", - "summary": "A powerful opioid derived from Morphine, with 2-4x its potency. Infamous for a high addiction potential and fatal respiratory depression in overdose, C. R. Alder Wright first synthesised this compound in 1874 trying to find a less addictive alternative to Morphine. In recent years, it has often been sold cut with the extremely potent fentanyl, causing a spike in overdose deaths.", - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "bioavailability": "Oral 35% | Intramuscular 85%", - "half-life": "2-3 minutes", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil Constriction, Analgesia.", - "after-effects": "1-24 hours." - }, - "pretty_name": "Heroin", - "aliases": [ - "diamorphine" - ], - "categories": [ - "opioid", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Insufflated": { - "Light": "7.5-20mg", - "Common": "20-35mg", - "Strong": "35-50mg", - "Heavy": "50-75mg" - }, - "Smoked": { - "Light": "5-15mg", - "Common": "15-25mg", - "Heavy": "30-50mg" - }, - "Intravenous": { - "Common": "5-10mg", - "Strong": "8-15mg" - } - }, - "formatted_duration": { - "Insufflated": "3-6", - "IV": "4-5", - "Smoked": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "Insufflated": "10-15", - "Smoked": "5-10", - "IV": "0-5", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil Constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Heroin.shtml" - }, - "pweffects": { - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Respiratory depression": "https://psychonautwiki.org/wiki/Respiratory_depression", - "Sedation": "https://psychonautwiki.org/wiki/Sedation" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " Note: Heroin dose varies greatly depending on quality and tolerance.", - "sources": { - "_general": [ - "Disrupted white matter integrity in heroin dependence: a controlled study utilizing diffusion tensor imaging - http://www.ncbi.nlm.nih.gov/pubmed/18720268", - "The treatment of heroin addicts with dextromethorphan: a double-blind comparison of dextromethorphan with chlorpromazine - http://www.ncbi.nlm.nih.gov/pubmed/2187002", - "Effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) and quipazine on heroin self-administration in rhesus monkeys - http://www.ncbi.nlm.nih.gov/pubmed/22836370", - "Heroin \"overdose\" death: contribution of drug-associated environmental cues - http://www.ncbi.nlm.nih.gov/pubmed/7200260", - "Methadone trials have proven successful in treating Heroin addiction - http://jamanetwork.com/journals/jama/article-abstract/656315", - "Heroin has been linked to reduction in testosterone and DHT levels - http://www.sciencedirect.com/science/article/pii/0300483X79900167" - ] - }, - "id": 514 - }, - "propoxyphene": { - "name": "propoxyphene", - "properties": { - "dose": "Light: 30-65mg Common: 65-100 Strong: 100-200mg. NOTE: Just don't take this drug. <3", - "summary": "Is an analgesic in the opioid family. It is intended for mild pain and for its antitussive effects. Has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias.", - "duration": "1-3 hours.", - "onset": "20-30 minutes.", - "after-effects": "2-6 hours.", - "categories": [ - "opioid", - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Propoxyphene", - "categories": [ - "opioid", - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "30-65mg", - "Common": "65-100", - "Strong": "100-200mg.", - "NOTE": "Just" - } - }, - "formatted_duration": { - "value": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "id": 515 - }, - "4-fmc": { - "name": "4-fmc", - "properties": { - "summary": "A cathinone stimulant also known as flephedrone, appeared in 2008 marketed as a mephedrone replacement. With some mild empathogenic effects, it failed to achieve widespread popularity.", - "duration": "Oral: 2-4 hours. Insufflated: 1-3 hours.", - "dose": "Oral Light: 50-100mg Common: 100-150mg Strong: 150-200+mg | Insufflated Light: 25-40mg Common: 50-100mg Strong: 100-150+mg", - "onset": "Oral: 15-30 minutes. Insufflated 1-5 minutes.", - "after-effects": "1-4 hours.", - "aliases": [ - "4-fluoromethcathinone", - "fpephedrone", - "flephedrone", - "4fmc" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, decreased need for sleep, increased sociability, mood lift, increased sexuality, excessive talking, decreased appetite, weight loss, sweating, disturbed sleep patterns, bruxism, visual and auditory hallucinations, itchiness, aggressiveness, moodiness." - }, - "pretty_name": "4-FMC", - "aliases": [ - "4-fluoromethcathinone", - "fpephedrone", - "flephedrone", - "4fmc" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-100mg", - "Common": "100-150mg", - "Strong": "150-200+mg" - }, - "Insufflated": { - "Light": "25-40mg", - "Common": "50-100mg", - "Strong": "100-150+mg" - } - }, - "formatted_duration": { - "Oral": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "decreased need for sleep", - "increased sociability", - "mood lift", - "increased sexuality", - "excessive talking", - "decreased appetite", - "weight loss", - "sweating", - "disturbed sleep patterns", - "bruxism", - "visual and auditory hallucinations", - "itchiness", - "aggressiveness", - "moodiness", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4Fluoromethcathinone.shtml" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "id": 516 - }, - "kratom": { - "name": "kratom", - "properties": { - "onset": "10-40 minutes.", - "duration": "2-5 hours", - "effects": "Simultaneous stimulation & sedation. Feelings of empathy. Feelings of euphoria. Aphrodisiac qualities for some people. Vivid waking dreams. Useful with physical labor", - "after-effects": "1-12 hours.", - "summary": "A drug made out of the leaves of Mitragyna Speciosa, which is related to coffee. Stimulating at lower doses, with opioid effects at higher doses. Frequent heavy use can cause physical addiction and withdrawals.", - "detection": "Kratom use is not detected by typical drug screening tests, but its metabolites can be detected by more specialized testing.", - "categories": [ - "opioid", - "stimulant", - "habit-forming", - "depressant", - "common" - ], - "dose": "Light: 0.5-1.5g Common: 1.5-3g Strong: 3-6g | Note: This is for plain leaf only. Some users experience stronger effects from lower doses compared to higher doses. It also is very different person to person, just use this as an outline, as it will change batch to batch and even dose to dose." - }, - "pretty_name": "Kratom", - "categories": [ - "opioid", - "stimulant", - "habit-forming", - "depressant", - "common" - ], - "formatted_dose": { - "Light:": { - "Light": "0.5-1.5g", - "Common": "1.5-3g", - "Strong": "3-6g" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-40", - "_unit": "minutes" - }, - "formatted_effects": [ - "Simultaneous stimulation & sedation", - "Feelings of empathy", - "Feelings of euphoria", - "Aphrodisiac qualities for some people", - "Vivid waking dreams", - "Useful with physical labor" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Kratom.shtml" - }, - "pweffects": { - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "Anxiety suppression": "https://psychonautwiki.org/wiki/Anxiety_suppression", - "Body odor alteration": "https://psychonautwiki.org/wiki/Body_odor_alteration", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Constipation": "https://psychonautwiki.org/wiki/Constipation", - "Cough suppression": "https://psychonautwiki.org/wiki/Cough_suppression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Double vision": "https://psychonautwiki.org/wiki/Double_vision", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Itchiness": "https://psychonautwiki.org/wiki/Itchiness", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Pain relief": "https://psychonautwiki.org/wiki/Pain_relief", - "Physical euphoria": "https://psychonautwiki.org/wiki/Physical_euphoria", - "Pupil constriction": "https://psychonautwiki.org/wiki/Pupil_constriction", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Visual disconnection": "https://psychonautwiki.org/wiki/Visual_disconnection" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " Note: This is for plain leaf only. Some users experience stronger effects from lower doses compared to higher doses. It also is very different person to person, just use this as an outline, as it will change batch to batch and even dose to dose.", - "sources": { - "_general": [ - "Seizure and coma following Kratom (Mitragynina speciosa Korth) exposure - http://www.ncbi.nlm.nih.gov/pubmed/20411370", - "A drug toxicity death involving propylhexedrine and mitragynine. - https://www.ncbi.nlm.nih.gov/pubmed/21219704", - "A drug toxicity death involving propylhexedrine and mitragynine - https://www.ncbi.nlm.nih.gov/pubmed/21219704" - ] - }, - "id": 517 - }, - "3-meo-pce": { - "name": "3-meo-pce", - "properties": { - "duration": "3-5 hours.", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "aliases": [ - "3meopce", - "methoxyieticyclidine" - ], - "summary": "3-MeO-PCP with a change of a ring replacement. Slightly more potent than 3-MeO-PCP.", - "dose": "Oral Light: 3-5mg Common: 5-10mg Strong: 10-20mg+", - "onset": "15-30 minutes.", - "after-effects": "1-6 hours." - }, - "pretty_name": "3-MeO-PCE", - "aliases": [ - "3meopce", - "methoxyieticyclidine" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Light": "3-5mg", - "Common": "5-10mg", - "Strong": "10-20mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_3MEOPCE_.shtml" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 518 - }, - "buphedrone": { - "name": "buphedrone", - "properties": { - "duration": "Oral: 2-3 hours | Insufflated: 1-2 hours", - "summary": "A cathinone stimulant first discovered in 1928, has gained some modest popularity as a mephedrone replacement. Said to be to be around 2-3x more potent than methcathinone.", - "dose": "Oral Light: 10-30mg Common: 30-50mg Heavy: 50-80mg", - "onset": "10-20 minutes", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Buphedrone", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "10-30mg", - "Common": "30-50mg", - "Heavy": "50-80mg" - } - }, - "formatted_duration": { - "Oral": "2-3", - "Insufflated": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-20", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 519 - }, - "adderall": { - "name": "adderall", - "properties": { - "dose": "Oral Light: 5-15mg Common: 15-40mg Strong: 40-75mg Heavy: 75-125mg+ | Insufflated Light: 5-10mg Common: 10-30mg Strong: 30-50mg Heavy: 50-80mg+ | NOTE: Adderall XR is extended release. Effects take a while to begin, and last much longer", - "summary": "A mixture of 75% dextroamphetamine and 25% levoamphetamine. Commonly used to treat obesity, narcolepsy and ADHD. It is also used widely either as a recreational stimulant or study-aid, particularly in the USA where it is frequently prescribed.", - "effects": "Increased alertness, Euphoria, Increased motivation, Reduced appetite, Flushing of the face, Increased body temperature, Tachycardia (Incrased heart rate) Paranoia, Insomnia.", - "duration": "Oral-IR: 4-6 hours. | Oral-XR: 6-12 hours. | Insufflated: 2-5 hours. | Note: Highly dependant on dose.", - "aliases": [ - "aderal", - "aderall", - "adderal", - "d-amphetamine", - "d-amph" - ], - "onset": "Oral-IR: 10-30 minutes | Oral-XR: 20-60 minutes | Insufflated-XR: 10-45 minutes | Insufflated-IR: 0-10 minutes", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "after-effects": "1-24 hours." - }, - "pretty_name": "Adderall", - "aliases": [ - "aderal", - "aderall", - "adderal", - "d-amphetamine", - "d-amph" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-15mg", - "Common": "15-40mg", - "Strong": "40-75mg", - "Heavy": "75-125mg+" - }, - "Insufflated": { - "Light": "5-10mg", - "Common": "10-30mg", - "Strong": "30-50mg", - "Heavy": "50-80mg+" - } - }, - "formatted_duration": { - "Oral-IR": "4-6", - "Oral-XR": "6-12", - "Insufflated": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "Oral-IR": "10-30", - "Oral-XR": "20-60", - "Insufflated-XR": "10-45", - "Insufflated-IR": "0-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Increased alertness", - "Euphoria", - "Increased motivation", - "Reduced appetite", - "Flushing of the face", - "Increased body temperature", - "Tachycardia (Incrased heart rate) Paranoia", - "Insomnia", - "" - ], - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Bronchodilation": "https://psychonautwiki.org/wiki/Bronchodilation", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temporary erectile dysfunction": "https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought organization": "https://psychonautwiki.org/wiki/Thought_organization", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Adderall XR is extended release. Effects take a while to begin, and last much longer", - "sources": { - "_general": [ - "Use of naltrexone has been found to successfully aid in recovery from amphetamine addiction - http://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2008.08020304" - ] - }, - "id": 520 - }, - "mushrooms": { - "name": "mushrooms", - "properties": { - "summary": "Fungi containing psilocybin, a prototypical psychedelic with similar effects to LSD, but with a shorter duration; also considered as being more confusing, introspective and entheogenic. Usually refers to psilocybe mushrooms rather than Amanitas, which have different effects. Are considered physically safe if properly identified, which should always be done by an expert.", - "dose": "Oral Light: 0.5-1.5g Common: 1.5-3.5g Strong: 3.5g+ | NOTE: Dosage ranges will vary between fungus strains. The doses given are for *dried* mushrooms, which are many times more potent by weight than those consumed when wet.", - "onset": "Varies depending on dosage, common doses (See ~drug mushrooms dose) are normally felt within one hour", - "effects": "visual distortion, color enhancement, sense of connectedness with nature, sense of well being, sense of wonder", - "duration": "4-6 hours", - "categories": [ - "psychedelic", - "common" - ], - "aliases": [ - "psilocybin", - "shrooms", - "mushroom", - "psylocybin" - ], - "half-life": "1-4 hours", - "after-effects": "1-24 hours." - }, - "pretty_name": "Mushrooms", - "aliases": [ - "psilocybin", - "shrooms", - "mushroom", - "psylocybin" - ], - "categories": [ - "psychedelic", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1.5g", - "Common": "1.5-3.5g", - "Strong": "3.5g+" - } - }, - "formatted_duration": { - "value": "4-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Varies" - }, - "formatted_effects": [ - "visual distortion", - "color enhancement", - "sense of connectedness with nature", - "sense of well being", - "sense of wonder" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Psilocybin.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Changes in gravity": "https://psychonautwiki.org/wiki/Changes_in_gravity", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Enhancement and suppression cycles": "https://psychonautwiki.org/wiki/Enhancement_and_suppression_cycles", - "Excessive yawning": "https://psychonautwiki.org/wiki/Excessive_yawning", - "Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/Exposure_to_inner_mechanics_of_consciousness", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Feelings of predeterminism": "https://psychonautwiki.org/wiki/Feelings_of_predeterminism", - "Feelings of self-design": "https://psychonautwiki.org/wiki/Feelings_of_self-design", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Mindfulness": "https://psychonautwiki.org/wiki/Mindfulness", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Runny nose": "https://psychonautwiki.org/wiki/Runny_nose", - "Salivation": "https://psychonautwiki.org/wiki/Salivation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations" - }, - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "dose_note": " NOTE: Dosage ranges will vary between fungus strains. The doses given are for *dried* mushrooms, which are many times more potent by weight than those consumed when wet.", - "sources": { - "_general": [ - "A study done on psilocybin leads psychiatrists to believe there are implications that it may help to treat ptsd - http://bjp.rcpsych.org/content/200/3/238.short" - ] - }, - "combos": { - "lsd": { - "status": "Low Risk & Synergy" - }, - "dmt": { - "status": "Low Risk & Synergy" - }, - "mescaline": { - "status": "Low Risk & Synergy" - }, - "dox": { - "status": "Low Risk & Synergy" - }, - "nbomes": { - "status": "Low Risk & Synergy" - }, - "2c-x": { - "status": "Low Risk & Synergy" - }, - "2c-t-x": { - "status": "Low Risk & Synergy" - }, - "amt": { - "status": "Low Risk & Synergy" - }, - "5-meo-xxt": { - "status": "Low Risk & Synergy" - }, - "cannabis": { - "status": "Caution", - "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics." - }, - "ketamine": { - "status": "Low Risk & Synergy" - }, - "mxe": { - "status": "Low Risk & Synergy" - }, - "dxm": { - "status": "Low Risk & Synergy" - }, - "pcp": { - "status": "Low Risk & Synergy" - }, - "nitrous": { - "status": "Low Risk & Synergy" - }, - "amphetamines": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "mdma": { - "status": "Low Risk & Synergy" - }, - "cocaine": { - "status": "Caution", - "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences" - }, - "caffeine": { - "status": "Low Risk & No Synergy" - }, - "alcohol": { - "status": "Low Risk & Decrease" - }, - "ghb/gbl": { - "status": "Low Risk & Decrease" - }, - "opioids": { - "status": "Low Risk & No Synergy" - }, - "tramadol": { - "status": "Unsafe", - "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures." - }, - "benzodiazepines": { - "status": "Low Risk & Decrease" - }, - "benzos": { - "status": "Low Risk & Decrease" - }, - "maois": { - "status": "Low Risk & Synergy" - }, - "ssris": { - "status": "Low Risk & Decrease" - } - }, - "id": 521 - }, - "hdep-28": { - "name": "hdep-28", - "properties": { - "summary": "Most likely a TRI, such as HDMP-28, short history of human use.", - "onset": "1-15 minutes.", - "duration": "2-5 hours.", - "avoid": "Other stimulants.", - "dose": "Oral Light: 15-30mg Common: 30-50mg Strong: 50-100mg | Insufflated Light: 5-15mg Common: 15-35mg Strong: 35-60mg", - "aliases": [ - "ethylnaphthidate" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "HDEP-28", - "aliases": [ - "ethylnaphthidate" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "15-30mg", - "Common": "30-50mg", - "Strong": "50-100mg" - }, - "Insufflated": { - "Light": "5-15mg", - "Common": "15-35mg", - "Strong": "35-60mg" - } - }, - "formatted_duration": { - "value": "2-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 522 - }, - "methallylescaline": { - "name": "methallylescaline", - "properties": { - "summary": "Mescaline analogue first synthesised by Alexander Shulgin, derived from and less potent than allylescaline. A psychedelic phenethylamine which causes stimulation, euphoria and hallucinatory experiences.", - "aliases": [ - "mal" - ], - "duration": "6-12 hours Varies GREATLY on dose.", - "onset": "20-60 minutes.", - "dose": "Oral Threshold: 10-15mg Low: 15-25mg Common: 25-40mg Heavy: 40mg+", - "after-effects": "3-5 hours.", - "categories": [ - "psychedelic", - "research-chemical" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia." - }, - "pretty_name": "Methallylescaline", - "aliases": [ - "mal" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "10-15mg", - "Low": "15-25mg", - "Common": "25-40mg", - "Heavy": "40mg+" - } - }, - "formatted_duration": { - "value": "6-12", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-60", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Methallylescaline.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal099.shtml" - }, - "pweffects": { - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "3-5", - "_unit": "hours" - }, - "id": 523 - }, - "2c-p": { - "name": "2c-p", - "properties": { - "summary": "A synthetic phenylethlyamine that is sometimes compared in effects to 2C-E, yet with a much longer duration. With a much more pronouced bodyload. Is one of the most potent of the 2C-X series.", - "aliases": [ - "2cp" - ], - "dose": "Oral Light: 2-4mg Common: 4-6mg Strong: 6-10mg | Insufflated Light: 1-3mg Common: 3-5mg Strong: 5-10mg.", - "duration": "10-16 hours", - "onset": "Oral: 60-180 minutes | Insufflated: 15-45 minutes", - "after-effects": "6-24 hours", - "effects": "Euphoria, Giggling, Empathy, Insight, Brightened Colors, Closed/Open Eye Visuals, Enhanced Tactile-Sensation, Mental/Physical Stimulation, Decreased Appetite, Pupil-Dilation, Restlessness, Changes in Perception-Of-Time, Ego-Softening, Nausea, Sweating/Chills, Muscle-Tension, Confusion, Insomnia", - "categories": [ - "psychedelic", - "research-chemical" - ], - "test-kits": "Marquis: Yellow. | Mecke: Green > Brown. | Mandelin: Green. | Froehde: Green. | Liebermann: Green. | Ehrlich: No colour change." - }, - "pretty_name": "2C-P", - "aliases": [ - "2cp" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "2-4mg", - "Common": "4-6mg", - "Strong": "6-10mg" - }, - "Insufflated": { - "Light": "1-3mg", - "Common": "3-5mg", - "Strong": "5-10mg." - } - }, - "formatted_duration": { - "value": "10-16", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "60-180", - "Insufflated": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Giggling", - "Empathy", - "Insight", - "Brightened Colors", - "Closed/Open Eye Visuals", - "Enhanced Tactile-Sensation", - "Mental/Physical Stimulation", - "Decreased Appetite", - "Pupil-Dilation", - "Restlessness", - "Changes in Perception-Of-Time", - "Ego-Softening", - "Nausea", - "Sweating/Chills", - "Muscle-Tension", - "Confusion", - "Insomnia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CP.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal036.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Depth perception distortions": "https://psychonautwiki.org/wiki/Depth_perception_distortions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Machinescapes": "https://psychonautwiki.org/wiki/Machinescapes", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Personal meaning enhancement": "https://psychonautwiki.org/wiki/Personal_meaning_enhancement", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Unspeakable horrors": "https://psychonautwiki.org/wiki/Unspeakable_horrors" - }, - "formatted_aftereffects": { - "value": "6-24", - "_unit": "hours" - }, - "id": 524 - }, - "amobarbital": { - "name": "amobarbital", - "properties": { - "summary": "A sedative and hypnotic barbiturate first discovered in 1923. Formerly widely used recreationally and medically, barbiturates have declined in popularity with the appearance of benzodiazepines and other drugs with less serious consequences in overdose.", - "duration": "5-9 hours", - "onset": "10-30 minutes.", - "dose": "Low: 50mg Common: 50-75mg Strong: 75-150mg+", - "avoid": "All other CNS depressants.", - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "bioavaiability": "Oral: Roughly 95%.", - "after-effects": "2-12 hours." - }, - "pretty_name": "Amobarbital", - "categories": [ - "depressant", - "habit-forming", - "barbiturate" - ], - "formatted_dose": { - "Oral": { - "Low": "50mg", - "Common": "50-75mg", - "Strong": "75-150mg+" - } - }, - "formatted_duration": { - "value": "5-9", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-30", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "2-12", - "_unit": "hours" - }, - "id": 525 - }, - "mexazolam": { - "name": "mexazolam", - "properties": { - "summary": "Benzodiazepine derivative that has been trialed for anxiety and was found to be effective for anxiety at one week week follow-ups yet after three weeks it had lost its therapeutic anxiolytic properties and becoming no more effective than placebo.", - "dose": "Oral Light: 0.25-0.5mg Common: 0.5-1.5mg Strong: 1.5-2mg Heavy: 2-3mg.", - "onset": "5-45 minutes.", - "duration": "4-8 hours.", - "after-effects": "1-12 hours.", - "aliases": [ - "melex", - "sedoxil" - ], - "categories": [ - "depressant", - "habit-forming" - ] - }, - "pretty_name": "Mexazolam", - "aliases": [ - "melex", - "sedoxil" - ], - "categories": [ - "depressant", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "0.25-0.5mg", - "Common": "0.5-1.5mg", - "Strong": "1.5-2mg", - "Heavy": "2-3mg." - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "5-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 526 - }, - "modafinil": { - "name": "modafinil", - "properties": { - "summary": "A wakefulness promoting, long acting stimulant which is typically only used functionally, because there is no real euphoric component to its effects. Also prescribed for daytime sleeping disorders.", - "dose": "Common: 100-300mg", - "onset": "30-45 minutes", - "duration": "12-16 hours.", - "categories": [ - "stimulant", - "habit-forming", - "nootropic", - "common" - ], - "aliases": [ - "provigil" - ], - "after-effects": "1-16 hours." - }, - "pretty_name": "Modafinil", - "aliases": [ - "provigil" - ], - "categories": [ - "stimulant", - "habit-forming", - "nootropic", - "common" - ], - "formatted_dose": { - "Oral": { - "Common": "100-300mg" - } - }, - "formatted_duration": { - "value": "12-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Modafinil.shtml" - }, - "pweffects": { - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Body odor alteration": "https://psychonautwiki.org/wiki/Body_odor_alteration", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Diarrhea": "https://psychonautwiki.org/wiki/Diarrhea", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Photophobia": "https://psychonautwiki.org/wiki/Photophobia", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-16", - "_unit": "hours" - }, - "sources": { - "_general": [ - "Modafinil augmentation of selective serotonin reuptake inhibitor therapy in MDD partial responders with persistent fatigue and sleepiness. - http://www.ncbi.nlm.nih.gov/pubmed/17729016", - "Pharmacogenetics of modafinil after sleep loss: catechol-O-methyltransferase genotype modulates waking functions but not recovery sleep. - http://www.ncbi.nlm.nih.gov/pubmed/19037200", - "Evidence for the involvement of dopamine transporters in behavioral stimulant effects of modafinil. - http://www.ncbi.nlm.nih.gov/pubmed/19197004", - "Effects of modafinil on attention performance, short-term memory and executive function in university students: a randomized trial. - http://www.ncbi.nlm.nih.gov/pubmed/26135067", - "The vigilance promoting drug modafinil decreases GABA release in the medial preoptic area and in the posterior hypothalamus of the awake rat: possi... - http://www.ncbi.nlm.nih.gov/pubmed/8977135", - "Modafinil has been found to interact with oral anti contraceptives, causing mainly low dosage regiments of steroidal drugs to be weakened to the point of no longer working. - http://www.modafinilfacts.com/contraceptives.htm" - ] - }, - "id": 527 - }, - "pre-084": { - "name": "pre-084", - "properties": { - "summary": "A sigma-1 receptor agonist derived structurally from PCP. It has cognitive enhancing effects as well as antidepressant effects, and shows promise in treating many nervous system diseases such as ALS and parkinsons.", - "categories": [ - "tentative" - ], - "onset": "15-30 minutes.", - "duration": "6-10 hours.", - "note": "Not much is known about this drug, so be cautious." - }, - "pretty_name": "PRE-084", - "categories": [ - "tentative" - ], - "formatted_duration": { - "value": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-30", - "_unit": "minutes" - }, - "id": 528 - }, - "benzodioxole-fentanyl": { - "name": "benzodioxole-fentanyl", - "properties": { - "summary": "An analogue of Fentanyl that is not found in literature.", - "categories": [ - "opioid", - "depressant", - "research-chemical", - "tentative" - ] - }, - "pretty_name": "BENZODIOXOLE-FENTANYL", - "categories": [ - "opioid", - "depressant", - "research-chemical", - "tentative" - ], - "id": 529 - }, - "mem": { - "name": "mem", - "properties": { - "duration": "8-16 hours (Highly dependant on dose)", - "summary": "A rare stimulant, psychedelic and amphetamine discovered by Alexander Shulgin. Related to the DOx class of drugs, little is known about this obscure compound's pharmacology, however it is likely to be potent and have a long duration.", - "dose": "Threshold: 15mg Low: 15-25mg Common: 25-35mg Strong: 35-45mg+.", - "onset": "Within 60 minutes.", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "effects": "Euphoria, empathy, insight, brightened colour, Closed/Open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception, ego softening, sweating/chills, muscle tension, confusion, insomnia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "MEM", - "categories": [ - "psychedelic", - "research-chemical", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Threshold": "15mg", - "Low": "15-25mg", - "Common": "25-35mg", - "Strong": "35-45mg+." - } - }, - "formatted_duration": { - "value": "8-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Within", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "empathy", - "insight", - "brightened colour", - "Closed/Open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception", - "ego softening", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_MEM.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal122.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 530 - }, - "pyrophenidone": { - "name": "pyrophenidone", - "properties": { - "summary": "An NDRI pyrovalerone derivative reported to have very similar subjective effects. Virtually no information exists about this drug's effects in humans.", - "dose": "Vaporized Light: 5-10mg Common: 10-25mg Strong: 25-50mg Heavy: 50mg+. | Insufflated Light: 20-40mg Common: 40-60mg Strong: 60-90mg Heavy: 90mg+", - "duration": "Vaporized: 1-1.5 hours | Insufflated: 1-3 hours", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "onset": "Vaporized 1-30 seconds. | Insufflated 5-15 minutes.", - "after-effects": "1-3 hours." - }, - "pretty_name": "Pyrophenidone", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "tentative" - ], - "formatted_dose": { - "Vaporized": { - "Light": "5-10mg", - "Common": "10-25mg", - "Strong": "25-50mg", - "Heavy": "50mg+." - }, - "Insufflated": { - "Light": "20-40mg", - "Common": "40-60mg", - "Strong": "60-90mg", - "Heavy": "90mg+" - } - }, - "formatted_duration": { - "Vaporized": "1-1.5", - "Insufflated": "1-3", - "_unit": "hours" - }, - "formatted_onset": { - "Vaporized": "1-30", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-3", - "_unit": "hours" - }, - "id": 531 - }, - "hdmp-28": { - "name": "hdmp-28", - "properties": { - "summary": "Also commonly known as methylnapthidate. A functional stimulant similar to methylphenidate but with a longer duration. Not especially recreational.", - "dose": "Oral Threshold: 8-10mg Light: 10-15 Common: 15-30mg Strong: 30-50mg+", - "onset": "1-10 minutes.", - "duration": "2-4 hours. (Dose dependent)", - "avoid": "Other stimulants.", - "aliases": [ - "methylnaphtidate" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "HDMP-28", - "aliases": [ - "methylnaphtidate" - ], - "categories": [ - "stimulant", - "research-chemical", - "tentative", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "8-10mg", - "Light": "10-15", - "Common": "15-30mg", - "Strong": "30-50mg+" - } - }, - "formatted_duration": { - "value": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "value": "1-10", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_HDMP28.shtml" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 532 - }, - "fasoracetam": { - "name": "fasoracetam", - "properties": { - "summary": "A substance in the racetam family. Appears to be a GABA(B) agonist, and has shown to block memory disruptions caused by Baclofen, another GABA(B) Agonist. Similar to another compound in the racetam family Coluracetam, it enhances High affinity choline reuptake (HACU). Also research is conducted if it helps with ADHD and Congitive impairment.", - "dose": "Low: 2.5-5mg Common: 5-10mg Strong: 10-25mg.", - "duration": "4-8 hours.", - "onset": "10-45 minutes.", - "categories": [ - "research-chemical", - "nootropic", - "tentative" - ], - "after-effects": "1-6 hours." - }, - "pretty_name": "Fasoracetam", - "categories": [ - "research-chemical", - "nootropic", - "tentative" - ], - "formatted_dose": { - "Oral": { - "Low": "2.5-5mg", - "Common": "5-10mg", - "Strong": "10-25mg." - } - }, - "formatted_duration": { - "value": "4-8", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-6", - "_unit": "hours" - }, - "id": 533 - }, - "amphetamine": { - "name": "amphetamine", - "properties": { - "dose": "Insufflated Light: 15-25mg Common: 25-40mg Strong: 40-75mg Heavy: 75-100mg | Oral Light: 10-20mg Common: 20-50mg Strong: 50-70mg Heavy: 70-90mg | NOTE: Street amphetamine is generally very impure, if you're working with a more pure chemical, lower doses will have greater effects.", - "duration": "Oral: 4-8 hours | Insufflated: 3-6 hours", - "effects": "Increased focus, abundance of energy, racing thoughts, elevated heartrate.", - "summary": "A very popular CNS stimulant available on prescription and black markets. Recreational in high doses, producing mild euphoria and an abundance of energy. Popular in eastern europe and the US.", - "onset": "Oral: 15-30 minutes. | Insufflated: 5-10 minutes.", - "detection": "Blood: 12 hours. Saliva: ~3 days. Urine: 1-4 days. Hair: Up to 90 days.", - "after-effects": "1-12 hours.", - "aliases": [ - "speed", - "pepp", - "amphetamines", - "amphetamin", - "amfetamine", - "amph", - "hearts", - "pep" - ], - "marquis": "Strong reddish orange - Dark reddish brown", - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "avoid": "other stimulants, and depressants. Mixing depressants and stimulants is very rough on the heart. MXE is also to be avoided (possibility of serotonin syndrome).", - "pubchemcid": "92939" - }, - "pretty_name": "Amphetamine", - "aliases": [ - "speed", - "pepp", - "amphetamines", - "amphetamin", - "amfetamine", - "amph", - "hearts", - "pep" - ], - "categories": [ - "stimulant", - "habit-forming", - "common" - ], - "formatted_dose": { - "Insufflated": { - "Light": "15-25mg", - "Common": "25-40mg", - "Strong": "40-75mg", - "Heavy": "75-100mg" - }, - "Oral": { - "Light": "10-20mg", - "Common": "20-50mg", - "Strong": "50-70mg", - "Heavy": "70-90mg" - } - }, - "formatted_duration": { - "Oral": "4-8", - "Insufflated": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "Insufflated": "5-10", - "_unit": "minutes" - }, - "formatted_effects": [ - "Increased focus", - "abundance of energy", - "racing thoughts", - "elevated heartrate", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Amphetamines.shtml" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Bronchodilation": "https://psychonautwiki.org/wiki/Bronchodilation", - "Cognitive euphoria": "https://psychonautwiki.org/wiki/Cognitive_euphoria", - "Cognitive fatigue": "https://psychonautwiki.org/wiki/Cognitive_fatigue", - "Compulsive redosing": "https://psychonautwiki.org/wiki/Compulsive_redosing", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Increased perspiration": "https://psychonautwiki.org/wiki/Increased_perspiration", - "Irritability": "https://psychonautwiki.org/wiki/Irritability", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Teeth grinding": "https://psychonautwiki.org/wiki/Teeth_grinding", - "Temporary erectile dysfunction": "https://psychonautwiki.org/wiki/Temporary_erectile_dysfunction", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought organization": "https://psychonautwiki.org/wiki/Thought_organization", - "Vasoconstriction": "https://psychonautwiki.org/wiki/Vasoconstriction", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Street amphetamine is generally very impure, if you're working with a more pure chemical, lower doses will have greater effects.", - "sources": { - "_general": [ - "Treatment for amphetamine dependence and abuse. - http://www.ncbi.nlm.nih.gov/pubmed/11687171", - "Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic models - https://www.ncbi.nlm.nih.gov/pubmed/16143730", - "Treatment for amphetamine dependence and abuse. - https://www.ncbi.nlm.nih.gov/pubmed/11687171", - "Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model ps... - https://www.ncbi.nlm.nih.gov/pubmed/16143730", - "The beta-lactam antibiotic ceftriaxone inhibits physical dependence and abstinence-induced withdrawal from cocaine, amphetamine, methamphetamine, a... - https://www.ncbi.nlm.nih.gov/pubmed/18342307", - "A comparison of methylphenidate-, amphetamine-, and methamphetamine-induced hyperthermia and neurotoxicity in male Sprague-Dawley rats during the w... - https://www.ncbi.nlm.nih.gov/pubmed/22289608", - "Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psyc... - https://www.ncbi.nlm.nih.gov/pubmed/3527341", - "L-DOPA exacerbates amphetamine-induced dopamine depletion. - https://www.ncbi.nlm.nih.gov/pubmed/9565967", - "Amphetamines in the treatment of Parkinson's disease. - http://www.ncbi.nlm.nih.gov/pubmed/1097600", - "Effect of dopamine D2/D3 receptor antagonist sulpiride on amphetamine-induced changes in striatal extracellular dopamine. - http://www.ncbi.nlm.nih.gov/pubmed/11343690", - "Behavioral and neuropharmacological analysis of amphetamine and 2,5-dimethoxy-4-methylamphetamine in rats. - http://www.ncbi.nlm.nih.gov/pubmed/1208759", - "Identification of di(beta-phenylisopropyl)amine as the main ingredient in illicit amphetamine tablets. - http://www.ncbi.nlm.nih.gov/pubmed/12645186", - "Long-term opiate effects on amphetamine-induced dopamine release in the nucleus accumbens core and conditioned place preference. - http://www.ncbi.nlm.nih.gov/pubmed/14751461", - "Microglial activation is a pharmacologically specific marker for the neurotoxic amphetamines. - http://www.ncbi.nlm.nih.gov/pubmed/15337264", - "Caffeine induces differential cross tolerance to the amphetamine-like discriminative stimulus effects of dopaminergic agonists. - http://www.ncbi.nlm.nih.gov/pubmed/15833596", - "Christmas gingerbread (Lebkuchen) and Christmas cheer--review of the potential role of mood elevating amphetamine-like compounds formed in vivo and... - http://www.ncbi.nlm.nih.gov/pubmed/16007907", - "Dual intoxication with diazepam and amphetamine: this drug interaction probably potentiates myocardial ischemia. - http://www.ncbi.nlm.nih.gov/pubmed/17320309", - "Update on amphetamine neurotoxicity and its relevance to the treatment of ADHD. - http://www.ncbi.nlm.nih.gov/pubmed/17606768", - "Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5-HT levels in nucleus accumbens of awake rats. - http://www.ncbi.nlm.nih.gov/pubmed/21615721", - "Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. - http://www.ncbi.nlm.nih.gov/pubmed/24296074", - "Long-lasting effects of escalating doses of d-amphetamine on brain monoamines, amphetamine-induced stereotyped behavior and spontaneous nocturnal l... - http://www.ncbi.nlm.nih.gov/pubmed/2440058", - "Amphetamine modulates excitatory neurotransmission through endocytosis of the glutamate transporter EAAT3 in dopamine neurons. - http://www.ncbi.nlm.nih.gov/pubmed/25033183", - "Acute methoxetamine and amphetamine poisoning with fatal outcome: a case report. - http://www.ncbi.nlm.nih.gov/pubmed/25060403", - "[Antitussive effect of amphetamine]. - http://www.ncbi.nlm.nih.gov/pubmed/552131", - "Amphetamine-clonidine interaction on neurotransmission in the vas deferens of the rat. - http://www.ncbi.nlm.nih.gov/pubmed/6098834", - "Self-injection of amphetamine directly into the brain. - http://www.ncbi.nlm.nih.gov/pubmed/6415748", - "Amphetamine-induced analgesia does not involve brain opioids. - http://www.ncbi.nlm.nih.gov/pubmed/6468501", - "Amphetamine-metabolites of deprenyl involved in protection against neurotoxicity induced by MPTP and 2'-methyl-MPTP. - http://www.ncbi.nlm.nih.gov/pubmed/7931228", - "L-DOPA exacerbates amphetamine-induced dopamine depletion. - http://www.ncbi.nlm.nih.gov/pubmed/9565967", - "Long-lasting psychotomimetic consequences of repeated low-dose amphetamine exposure in rhesus monkeys. - http://www.ncbi.nlm.nih.gov/pubmed/9885781", - "Use of naltrexone has been found to successfully aid in recovery from amphetamine addiction - http://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2008.08020304", - "According to drugs.com 's interaction checker, there is a potential for serotonin syndrome when mixing amphetamines and ssri's. The threshold dose for danger however is unknown. https://www.drugs.com/interactions-check.php?drug_list=2543-0,679-0", - "Amphetamine has a half life of 7-31 hours: Mosby's Dental Drug Reference Ninth Edition 2010", - "Pregnancy category C according to the FDA. Evidence has shown usage during pregnancy can cause premature birth, low birthweight, and withdrawal syndrome in the baby. This occurs more often in abuse of adderall. Recommendation is to consult with a physician if you are pregnant.", - "Pregnancy category C according to the FDA. - https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/011522s040lbl.pdf" - ] - }, - "id": 534 - }, - "flutoprazepam": { - "name": "flutoprazepam", - "properties": { - "summary": "A potent benzodiazepine that is roughly 4-5x the potency of Diazepam and has a longer duration, rarely seen outside of Japan. Sedative, hypnotic and anxiolytic. May cause amnesia and loss of inhibitions in excess. Do not mix with other depressants.", - "duration": "12-16 hours", - "after-effects": "24-36 hours", - "avoid": "All other CNS depressants.", - "dose": "Light: 0.5-1mg Common: 1.5-3mg Strong: 3-5mg+", - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "aliases": [ - "restas" - ], - "onset": "15-45 minutes.", - "effects": "Anxiolytic, Sedative, Muscle Relaxant, Amnesia, Dystaxia, Hypnotic.", - "dose_to_diazepam": "Flutoprazepam - ~2.5mg ~=10mg Diazepam." - }, - "pretty_name": "Flutoprazepam", - "aliases": [ - "restas" - ], - "categories": [ - "benzodiazepine", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "0.5-1mg", - "Common": "1.5-3mg", - "Strong": "3-5mg+" - } - }, - "formatted_duration": { - "value": "12-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "15-45", - "_unit": "minutes" - }, - "formatted_effects": [ - "Anxiolytic", - "Sedative", - "Muscle Relaxant", - "Amnesia", - "Dystaxia", - "Hypnotic", - "" - ], - "formatted_aftereffects": { - "value": "24-36", - "_unit": "hours" - }, - "id": 535 - }, - "5-eapb": { - "name": "5-eapb", - "properties": { - "summary": "A empathogen sold as a replacement to 5-MAPB after it was banned in the UK, but said to be less enjoyable and never gained much popularity.", - "duration": "Oral: 5-6 hours Insufflated: 3-4 hours.", - "dose": "Oral Light: 50-60mg Common: 60-100mg Strong: 100-150+mg | Insufflated Light: 30-40mg Common: 40-60mg Strong: 60-100+mg", - "onset": "Oral 30-60 minutes Insufflated 5-10 minutes.", - "aliases": [ - "5eapb" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness." - }, - "pretty_name": "5-EAPB", - "aliases": [ - "5eapb" - ], - "categories": [ - "stimulant", - "psychedelic", - "research-chemical", - "empathogen", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Light": "50-60mg", - "Common": "60-100mg", - "Strong": "100-150+mg" - }, - "Insufflated": { - "Light": "30-40mg", - "Common": "40-60mg", - "Strong": "60-100+mg" - } - }, - "formatted_duration": { - "Oral": "5-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Oral", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "id": 536 - }, - "propranolol": { - "name": "propranolol", - "properties": { - "dose": "Oral Light: 10-30mg Common: 40-80mg Strong: 80-140mg.", - "onset": "10-45 minutes.", - "duration": "3-7 hours.", - "avoid": "All other CNS depressants.", - "summary": "Is a nonselective beta blocker. It is used in medication for high blood pressure, anxiety, and tremors. Also fun fact, it was the first successful beta-blocker developed.", - "aliases": [ - "inderal", - "hemangeol", - "innopran" - ], - "categories": [ - "depressant", - "common" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "Propranolol", - "aliases": [ - "inderal", - "hemangeol", - "innopran" - ], - "categories": [ - "depressant", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "10-30mg", - "Common": "40-80mg", - "Strong": "80-140mg." - } - }, - "formatted_duration": { - "value": "3-7", - "_unit": "hours" - }, - "formatted_onset": { - "value": "10-45", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 537 - }, - "pv-9": { - "name": "pv-9", - "properties": { - "summary": "Inactive.", - "categories": [ - "inactive" - ] - }, - "pretty_name": "PV-9", - "categories": [ - "inactive" - ], - "id": 538 - }, - "tapentadol": { - "name": "tapentadol", - "properties": { - "summary": "An opioid analgesic drug with potency somewhere between tramadol and morphine, and with a similar action to Tramadol. Also an adrenergic reuptake inhibitor. High addiction potential. Potential for respiratory depression in overdose. Should not be combined with depressants or stimulants.", - "onset": "Oral_IR: 20-40 minutes. | Oral_ER: 60-120 minutes.", - "duration": "Oral_IR: 3-5 hours | Oral_ER: 5-8 hours.", - "avoid": "All other CNS depressants", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "dose": "Oral Light: 25-50mg Common: 50-75mg Strong: 75-150mg+ | NOTE: Doses are for no tolerance. Insufflated administration is ineffective.", - "effects": "Euphoria, Dry Mouth, Mood lift, Itchiness, Relaxant, Constipation, Pupil constriction, Analgesia.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Tapentadol", - "categories": [ - "opioid", - "habit-forming", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "25-50mg", - "Common": "50-75mg", - "Strong": "75-150mg+" - } - }, - "formatted_duration": { - "Oral_IR": "3-5", - "Oral_ER": "5-8", - "_unit": "hours" - }, - "formatted_onset": { - "Oral_IR": "20-40", - "Oral_ER": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "Dry Mouth", - "Mood lift", - "Itchiness", - "Relaxant", - "Constipation", - "Pupil constriction", - "Analgesia", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Tapentadol.shtml" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "dose_note": " NOTE: Doses are for no tolerance. Insufflated administration is ineffective.", - "id": 539 - }, - "mxm": { - "name": "mxm", - "properties": { - "summary": "An arylcyclohexamine, dissociative and anaesthetic closely related to methoxetamine, ketamine and PCP. It has seen some popularity among RC users, being advertised as an MXE replacement after its illegalisation in many parts of the world - however, users report a more stimulating experience closer to those caused by PCP and its analogues.", - "dose": "Threshold: 10-20mg Light: 20-40mg Common: 40-60mg Strong: 60-100mg+", - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "duration": "3-5 hours. (Dependant on dose/ROA)", - "onset": "Varying widely from reports of 30 minutes up to four hours.", - "after-effects": "2-4 hours.", - "avoid": "CNS depressants.", - "aliases": [ - "methoxmetamine" - ] - }, - "pretty_name": "MXM", - "aliases": [ - "methoxmetamine" - ], - "categories": [ - "dissociative", - "research-chemical", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Threshold": "10-20mg", - "Light": "20-40mg", - "Common": "40-60mg", - "Strong": "60-100mg+" - } - }, - "formatted_duration": { - "value": "3-5", - "_unit": "hours" - }, - "formatted_onset": { - "value": "Varying", - "_unit": "hours" - }, - "formatted_aftereffects": { - "value": "2-4", - "_unit": "hours" - }, - "dose_note": " NOTE: (Once again, do not take this as a catch all.)", - "id": 540 - }, - "4-ho-mipt": { - "name": "4-ho-mipt", - "properties": { - "dose": "Oral Threshold: 5-10mg Light: 10-15mg Common: 15-20mg Strong: 20-30mg Heavy: 40mg+", - "summary": "A reasonably popular tryptamine deriviative and Psilocin analogue, first synthesised by Alexander Shulgin. It has been reported as having comparable effects to psychedelic mushrooms, though with a shorter duration.", - "duration": "3-6 hours", - "onset": "20-90 minutes depending on stomach contents.", - "effects": "Brightened colors, visual distortions, altered perception, a sense of conectedness with the world around you, heightend emotions, paranoia, unwanted thoughts.", - "aliases": [ - "4homipt", - "homipt", - "ho-mipt", - "4-ho", - "miprocin" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "after-effects": "1-8 hours." - }, - "pretty_name": "4-HO-MiPT", - "aliases": [ - "4homipt", - "homipt", - "ho-mipt", - "4-ho", - "miprocin" - ], - "categories": [ - "psychedelic", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Threshold": "5-10mg", - "Light": "10-15mg", - "Common": "15-20mg", - "Strong": "20-30mg", - "Heavy": "40mg+" - } - }, - "formatted_duration": { - "value": "3-6", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "Brightened colors", - "visual distortions", - "altered perception", - "a sense of conectedness with the world around you", - "heightend emotions", - "paranoia", - "unwanted thoughts", - "" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_4HOMiPT.shtml", - "tihkal": "https://www.erowid.org/library/books_online/tihkal/tihkal22.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Delusions": "https://psychonautwiki.org/wiki/Delusions", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Déjà vu": "https://psychonautwiki.org/wiki/D%C3%A9j%C3%A0_vu", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Enhancement and suppression cycles": "https://psychonautwiki.org/wiki/Enhancement_and_suppression_cycles", - "Feelings of interdependent opposites": "https://psychonautwiki.org/wiki/Feelings_of_interdependent_opposites", - "Feelings of predeterminism": "https://psychonautwiki.org/wiki/Feelings_of_predeterminism", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Runny nose": "https://psychonautwiki.org/wiki/Runny_nose", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Sedation": "https://psychonautwiki.org/wiki/Sedation", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Subconscious communication": "https://psychonautwiki.org/wiki/Subconscious_communication", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Thought loops": "https://psychonautwiki.org/wiki/Thought_loops", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Unity and interconnectedness": "https://psychonautwiki.org/wiki/Unity_and_interconnectedness", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness", - "Watery eyes": "https://psychonautwiki.org/wiki/Watery_eyes" - }, - "formatted_aftereffects": { - "value": "1-8", - "_unit": "hours" - }, - "id": 541 - }, - "2c-e": { - "name": "2c-e", - "properties": { - "dose": "Oral Light: 5-10mg Common: 10-15mg Strong: 15-30mg Heavy: 25-40mg | Insufflated Light: 1-3mg Common: 3-7mg Strong: 6-10mg Heavy: 10mg+", - "aliases": [ - "2ce" - ], - "duration": "6-14 hours (depending on dose)", - "onset": "20-90 minutes", - "summary": "An intense psychedelic drug with very strong visuals, sometimes criticised for its relatively uncomfortable body load. Otherwise, effects are comparable to other 2c-x drugs.", - "effects": "euphoria, giggling, empathy, insight, brightened color, closed/open eye visuals, enhanced tactile sensation, mental/physical stimulation, decreased appetite, pupil dilation, restlessness, change in perception of time, ego softening, nausea, sweating/chills, muscle tension, confusion, insomnia", - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "after-effects": "2-6 hours", - "test-kits": "Marquis: Yellow-Pale Brown. | Mecke: Yellow > Brown. | Mandelin: Yellow-Green. | Froehde: Yellow. | Liebermann: Yellow > Black. | Simon's: No colour change. | Ehrlich: No colour change." - }, - "pretty_name": "2C-E", - "aliases": [ - "2ce" - ], - "categories": [ - "psychedelic", - "research-chemical", - "common" - ], - "formatted_dose": { - "Oral": { - "Light": "5-10mg", - "Common": "10-15mg", - "Strong": "15-30mg", - "Heavy": "25-40mg" - }, - "Insufflated": { - "Light": "1-3mg", - "Common": "3-7mg", - "Strong": "6-10mg", - "Heavy": "10mg+" - } - }, - "formatted_duration": { - "value": "6-14", - "_unit": "hours" - }, - "formatted_onset": { - "value": "20-90", - "_unit": "minutes" - }, - "formatted_effects": [ - "euphoria", - "giggling", - "empathy", - "insight", - "brightened color", - "closed/open eye visuals", - "enhanced tactile sensation", - "mental/physical stimulation", - "decreased appetite", - "pupil dilation", - "restlessness", - "change in perception of time", - "ego softening", - "nausea", - "sweating/chills", - "muscle tension", - "confusion", - "insomnia" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_2CE.shtml", - "pihkal": "https://www.erowid.org/library/books_online/pihkal/pihkal024.shtml" - }, - "pweffects": { - "8B Geometry - Exposure to inner mechanics of consciousness": "https://psychonautwiki.org/wiki/8B_Geometry_-_Exposure_to_inner_mechanics_of_consciousness", - "Acuity enhancement": "https://psychonautwiki.org/wiki/Acuity_enhancement", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Analysis enhancement": "https://psychonautwiki.org/wiki/Analysis_enhancement", - "Auditory distortion": "https://psychonautwiki.org/wiki/Auditory_distortion", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Bodily control enhancement": "https://psychonautwiki.org/wiki/Bodily_control_enhancement", - "Colour enhancement": "https://psychonautwiki.org/wiki/Colour_enhancement", - "Colour shifting": "https://psychonautwiki.org/wiki/Colour_shifting", - "Conceptual thinking": "https://psychonautwiki.org/wiki/Conceptual_thinking", - "Creativity enhancement": "https://psychonautwiki.org/wiki/Creativity_enhancement", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Empathy, love, and sociability enhancement": "https://psychonautwiki.org/wiki/Empathy,_love,_and_sociability_enhancement", - "Geometry": "https://psychonautwiki.org/wiki/Geometry", - "Immersion enhancement": "https://psychonautwiki.org/wiki/Immersion_enhancement", - "Increased blood pressure": "https://psychonautwiki.org/wiki/Increased_blood_pressure", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Memory suppression": "https://psychonautwiki.org/wiki/Memory_suppression", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Novelty enhancement": "https://psychonautwiki.org/wiki/Novelty_enhancement", - "Pattern recognition enhancement": "https://psychonautwiki.org/wiki/Pattern_recognition_enhancement", - "Personal bias suppression": "https://psychonautwiki.org/wiki/Personal_bias_suppression", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Scenery slicing": "https://psychonautwiki.org/wiki/Scenery_slicing", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Spirituality enhancement": "https://psychonautwiki.org/wiki/Spirituality_enhancement", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Symmetrical texture repetition": "https://psychonautwiki.org/wiki/Symmetrical_texture_repetition", - "Synaesthesia": "https://psychonautwiki.org/wiki/Synaesthesia", - "Tactile enhancement": "https://psychonautwiki.org/wiki/Tactile_enhancement", - "Temperature regulation suppression": "https://psychonautwiki.org/wiki/Temperature_regulation_suppression", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Thought connectivity": "https://psychonautwiki.org/wiki/Thought_connectivity", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Tracers": "https://psychonautwiki.org/wiki/Tracers", - "Transformations": "https://psychonautwiki.org/wiki/Transformations", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "2-6", - "_unit": "hours" - }, - "id": 542 - }, - "datura": { - "name": "datura", - "properties": { - "summary": "A family of plants containing various Tropane alkaloids. Produces long-lasting deliriant effects including very realistic and often unpleasant hallucinations along with short-term amnesia. Datura plants are toxic to humans, and potency varies greatly from plant-to-plant, making the drug extremely difficult to dose safely. Not typically regarded as recreational.", - "effects": "surreal interactions with world, hallucinations, dry mouth, nausea, fear, anxiety, amnesia, difficulty breathing, confusion, delirium", - "avoid": "Yes. Just avoid it.", - "duration": "12-72+ hours.", - "onset": "60-120 minutes", - "after-effects": "24-72 hours", - "categories": [ - "depressant", - "tentative", - "deliriant" - ], - "warning": "Datura can be incredibly dangerous, dosing can be hard to determine and caution should be used. In general this drug should be avoided." - }, - "pretty_name": "Datura", - "categories": [ - "depressant", - "tentative", - "deliriant" - ], - "formatted_dose": { - "none": { - "NOTE": "There" - } - }, - "formatted_duration": { - "value": "12-72+", - "_unit": "hours" - }, - "formatted_onset": { - "value": "60-120", - "_unit": "minutes" - }, - "formatted_effects": [ - "surreal interactions with world", - "hallucinations", - "dry mouth", - "nausea", - "fear", - "anxiety", - "amnesia", - "difficulty breathing", - "confusion", - "delirium" - ], - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Datura.shtml" - }, - "pweffects": { - "Abnormal heartbeat": "https://psychonautwiki.org/wiki/Abnormal_heartbeat", - "Acuity suppression": "https://psychonautwiki.org/wiki/Acuity_suppression", - "After images": "https://psychonautwiki.org/wiki/After_images", - "Amnesia": "https://psychonautwiki.org/wiki/Amnesia", - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Auditory enhancement": "https://psychonautwiki.org/wiki/Auditory_enhancement", - "Auditory hallucinations": "https://psychonautwiki.org/wiki/Auditory_hallucinations", - "Autonomous entities": "https://psychonautwiki.org/wiki/Autonomous_entities", - "Cognitive dysphoria": "https://psychonautwiki.org/wiki/Cognitive_dysphoria", - "Depression": "https://psychonautwiki.org/wiki/Depression", - "Difficulty urinating": "https://psychonautwiki.org/wiki/Difficulty_urinating", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Dream potentiation": "https://psychonautwiki.org/wiki/Dream_potentiation", - "Drifting": "https://psychonautwiki.org/wiki/Drifting", - "Emotion suppression": "https://psychonautwiki.org/wiki/Emotion_suppression", - "External hallucinations": "https://psychonautwiki.org/wiki/External_hallucinations", - "Frequent urination": "https://psychonautwiki.org/wiki/Frequent_urination", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Information processing suppression": "https://psychonautwiki.org/wiki/Information_processing_suppression", - "Internal hallucinations": "https://psychonautwiki.org/wiki/Internal_hallucinations", - "Language suppression": "https://psychonautwiki.org/wiki/Language_suppression", - "Muscle cramps": "https://psychonautwiki.org/wiki/Muscle_cramps", - "Muscle spasms": "https://psychonautwiki.org/wiki/Muscle_spasms", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Paranoia": "https://psychonautwiki.org/wiki/Paranoia", - "Pattern recognition suppression": "https://psychonautwiki.org/wiki/Pattern_recognition_suppression", - "Perception of increased weight": "https://psychonautwiki.org/wiki/Perception_of_increased_weight", - "Peripheral information misinterpretation": "https://psychonautwiki.org/wiki/Peripheral_information_misinterpretation", - "Perspective alterations": "https://psychonautwiki.org/wiki/Perspective_alterations", - "Photophobia": "https://psychonautwiki.org/wiki/Photophobia", - "Psychosis": "https://psychonautwiki.org/wiki/Psychosis", - "Pupil dilation": "https://psychonautwiki.org/wiki/Pupil_dilation", - "Restless leg syndrome": "https://psychonautwiki.org/wiki/Restless_leg_syndrome", - "Scenarios and plots": "https://psychonautwiki.org/wiki/Scenarios_and_plots", - "Settings, sceneries, and landscapes": "https://psychonautwiki.org/wiki/Settings,_sceneries,_and_landscapes", - "Shadow people": "https://psychonautwiki.org/wiki/Shadow_people", - "Spontaneous tactile sensations": "https://psychonautwiki.org/wiki/Spontaneous_tactile_sensations", - "Thought deceleration": "https://psychonautwiki.org/wiki/Thought_deceleration", - "Thought disorganization": "https://psychonautwiki.org/wiki/Thought_disorganization", - "Time distortion": "https://psychonautwiki.org/wiki/Time_distortion", - "Unspeakable horrors": "https://psychonautwiki.org/wiki/Unspeakable_horrors", - "Vibrating vision": "https://psychonautwiki.org/wiki/Vibrating_vision", - "Visual haze": "https://psychonautwiki.org/wiki/Visual_haze" - }, - "formatted_aftereffects": { - "value": "24-72", - "_unit": "hours" - }, - "id": 543 - }, - "thiopropamine": { - "name": "thiopropamine", - "properties": { - "summary": "A substance that is closely related to Methiopopramine (MPA). Is roughly about 1/3rd the potency of amphetamine, differs from amphetmine from the phenyl ring is switched with a thiophene ring.", - "dose": "Oral Light: 20-50mg Common: 50-100mg Strong: 100-125mg+", - "onset": "Oral: 15-45 minutes. | Insufflated: 5-15mg.", - "duration": "Oral: 1-4 hours. | Insufflated: 1-2 hours.", - "after-effects": "Oral: 1-3 hours | Insufflated: 1-2 hours.", - "categories": [ - "stimulant", - "habit-forming", - "research-chemical" - ], - "aliases": [ - "tpa", - "normethiopropamine", - "a-methyl-2-thipheneethanamine" - ] - }, - "pretty_name": "Thiopropamine", - "aliases": [ - "tpa", - "normethiopropamine", - "a-methyl-2-thipheneethanamine" - ], - "categories": [ - "stimulant", - "habit-forming", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "Light": "20-50mg", - "Common": "50-100mg", - "Strong": "100-125mg+" - } - }, - "formatted_duration": { - "Oral": "1-4", - "Insufflated": "1-2", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-45", - "Insufflated": "5-15mg.", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "Oral": "1-3", - "Insufflated": "1-2", - "_unit": "hours" - }, - "id": 544 - }, - "mdphp": { - "name": "mdphp", - "properties": { - "summary": "MDPHP aka 'Monkey-Dust' is a substituted cathinone and pyrovalerone which has been sold as an alternative to a-PHP and MDPV. Said to be less intense than MDPV with similar effects. MDPHP potency is said to vary widely, and there are reports of mixed composition batches containing other drugs. Very little is known about MDPHP in terms of toxicity, pharmacology and metabolism.", - "duration": "Oral: 3-6 hours | Insufflated/Inhaled: 2-4 hours", - "onset": "Oral: 30-60 minutes | Insufflated: 5-15 minutes", - "dose": "NOTE: Dose data is tentative; There is a large variance in potency and composition of batches, and as such caution should be used when taking MDPHP. See ~mdphp summary | Oral Light: 10-20mg Common: 20-35mg Strong: 35+mg | Insufflated/Inhaled Light: 5-10mg Common: 10-20mg Strong: 20+mg", - "onset:": "Oral: 2-36 minutes | Inflatted/Inhaled: 5-15 minutes", - "after-effects": "Oral: 2-16h | Insufflated/Inhaled: 2-36h", - "effects": "Stimulation, Incresed Motivation, Mood Enhancement, Euphoria, Sexual Enhancement, Anxiety, Paranoia, Dry Mouth, Muscle Tension, Restlessness, Uncomfortable Stimulation", - "categories": [ - "stimulant", - "tentative", - "habit-forming", - "research-chemical" - ], - "aliases": [ - "monkey-dust" - ] - }, - "pretty_name": "Mdphp", - "aliases": [ - "monkey-dust" - ], - "categories": [ - "stimulant", - "tentative", - "habit-forming", - "research-chemical" - ], - "formatted_dose": { - "Oral": { - "t": "10-20mg", - "Common": "20-35mg", - "Strong": "35+mg" - }, - "Insufflated/Inhaled": { - "Light": "5-10mg", - "Common": "10-20mg", - "Strong": "20+mg" - } - }, - "formatted_duration": { - "Oral": "3-6", - "Insufflated/Inhaled": "2-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-60", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Stimulation", - "Incresed Motivation", - "Mood Enhancement", - "Euphoria", - "Sexual Enhancement", - "Anxiety", - "Paranoia", - "Dry Mouth", - "Muscle Tension", - "Restlessness", - "Uncomfortable Stimulation" - ], - "formatted_aftereffects": { - "Oral": "2-16h", - "Insufflated/Inhaled": "2-36h" - }, - "dose_note": "NOTE: Dose data is tentative; There is a large variance in potency and composition of batches, and as such caution should be used when taking MDPHP. See ~mdphp summary ", - "id": 545 - }, - "butyrfentanyl": { - "name": "butyrfentanyl", - "properties": { - "summary": "Potent short-acting opioid and fentanyl analogue. Often dispensed in a nasal spray. This is an highly potent drug - exercise extreme caution. May cause respiratory depression and death in overdose.", - "onset": "Oral: 15-30 minutes. Insufflated: 5-10 minutes.", - "duration": "Oral: 3-4 hours. Insufflated: 2-3 hours.", - "alias": "b-f", - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "dose": "Oral Light: 400-800ug Common: 800-1500ug Strong: 1.5-3mg || Note: It's a potent drug, be careful.", - "aliases": [ - "bf", - "b-f" - ], - "avoid": "All other CNS depressants.", - "after-effects": "1-4 hours." - }, - "pretty_name": "Butyrfentanyl", - "aliases": [ - "bf", - "b-f" - ], - "categories": [ - "opioid", - "research-chemical", - "habit-forming", - "tentative", - "depressant" - ], - "formatted_dose": { - "Oral": { - "Light": "400-800ug", - "Common": "800-1500ug", - "Strong": "1.5-3mg" - }, - "": {} - }, - "formatted_duration": { - "Oral": "3-4", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "15-30", - "_unit": "minutes" - }, - "formatted_aftereffects": { - "value": "1-4", - "_unit": "hours" - }, - "dose_note": " Note: It's a potent drug, be careful.", - "id": 546 - }, - "armodafinil": { - "name": "armodafinil", - "properties": { - "summary": "The more potent of the two modafinil isomers, said to have a longer duration and lesser side effects. Sometimes prescribed for ADHD and daytime sleepiness.", - "dose": "Common: 50-150mg's", - "duration": "12-16 hours.", - "onset": "30-45 minutes.", - "categories": [ - "stimulant", - "nootropic", - "habit-forming" - ], - "aliases": [ - "nuvigil" - ], - "bioavailability": "Oral 97.78%.", - "after-effects": "1-12 hours." - }, - "pretty_name": "Armodafinil", - "aliases": [ - "nuvigil" - ], - "categories": [ - "stimulant", - "nootropic", - "habit-forming" - ], - "formatted_dose": { - "Oral": { - "Common": "50-150mg" - } - }, - "formatted_duration": { - "value": "12-16", - "_unit": "hours" - }, - "formatted_onset": { - "value": "30-45", - "_unit": "minutes" - }, - "links": { - "experiences": "https://www.erowid.org/experiences/subs/exp_Armodafinil.shtml" - }, - "pweffects": { - "Anxiety": "https://psychonautwiki.org/wiki/Anxiety", - "Appetite suppression": "https://psychonautwiki.org/wiki/Appetite_suppression", - "Body odor alteration": "https://psychonautwiki.org/wiki/Body_odor_alteration", - "Dehydration": "https://psychonautwiki.org/wiki/Dehydration", - "Diarrhea": "https://psychonautwiki.org/wiki/Diarrhea", - "Dizziness": "https://psychonautwiki.org/wiki/Dizziness", - "Emotion enhancement": "https://psychonautwiki.org/wiki/Emotion_enhancement", - "Focus enhancement": "https://psychonautwiki.org/wiki/Focus_enhancement", - "Headaches": "https://psychonautwiki.org/wiki/Headaches", - "Increased heart rate": "https://psychonautwiki.org/wiki/Increased_heart_rate", - "Increased libido": "https://psychonautwiki.org/wiki/Increased_libido", - "Memory enhancement": "https://psychonautwiki.org/wiki/Memory_enhancement", - "Motivation enhancement": "https://psychonautwiki.org/wiki/Motivation_enhancement", - "Nausea": "https://psychonautwiki.org/wiki/Nausea", - "Photophobia": "https://psychonautwiki.org/wiki/Photophobia", - "Stimulation": "https://psychonautwiki.org/wiki/Stimulation", - "Thought acceleration": "https://psychonautwiki.org/wiki/Thought_acceleration", - "Wakefulness": "https://psychonautwiki.org/wiki/Wakefulness" - }, - "formatted_aftereffects": { - "value": "1-12", - "_unit": "hours" - }, - "id": 547 - }, - "amfonelicacid": { - "name": "amfonelicacid", - "properties": { - "summary": "A dopaminergic stimulant discovered by Sterling-Winthrop accidentally while developing antibiotics. Discontinued due to undesirable stimulant effects, it has had some popularity as a recreational drug.", - "onset": "Oral: 30-45 minutes. | Insufflated: 5-15 minutes.", - "dose": "Threshold: 2-4mg Common: 4-10mg Strong: 10mg+", - "duration": "Oral: 8-12 hours. | Insufflated: 6-10 hours.", - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "nootropic" - ], - "aliases": [ - "aa", - "afa", - "win25978" - ], - "effects": "Euphoria, increased energy/alertness, Decreased need for sleep, Increased sociability, mood lift, increase sexuality, Excessive talking, Decreased appetite, Weight loss, Sweating, Distrubed sleep patterns, Bruxia, Visual and audiotory hallucinations itchiness, agressiveness, moodiness.", - "after-effects": "1-24 hours." - }, - "pretty_name": "Amfonelic acid", - "aliases": [ - "aa", - "afa", - "win25978" - ], - "categories": [ - "stimulant", - "research-chemical", - "habit-forming", - "nootropic" - ], - "formatted_dose": { - "Oral": { - "Threshold": "2-4mg", - "Common": "4-10mg", - "Strong": "10mg+" - } - }, - "formatted_duration": { - "Oral": "8-12", - "Insufflated": "6-10", - "_unit": "hours" - }, - "formatted_onset": { - "Oral": "30-45", - "Insufflated": "5-15", - "_unit": "minutes" - }, - "formatted_effects": [ - "Euphoria", - "increased energy/alertness", - "Decreased need for sleep", - "Increased sociability", - "mood lift", - "increase sexuality", - "Excessive talking", - "Decreased appetite", - "Weight loss", - "Sweating", - "Distrubed sleep patterns", - "Bruxia", - "Visual and audiotory hallucinations itchiness", - "agressiveness", - "moodiness", - "" - ], - "formatted_aftereffects": { - "value": "1-24", - "_unit": "hours" - }, - "id": 548 - } -} \ No newline at end of file diff --git a/tripsit/getAllDrugs.py b/tripsit/getAllDrugs.py deleted file mode 100644 index 41b3f17..0000000 --- a/tripsit/getAllDrugs.py +++ /dev/null @@ -1,27 +0,0 @@ -import requests, json -import pandas as pd - -# API URL -url = "http://tripbot.tripsit.me/api/tripsit/getAllDrugs" -r = requests.get(url) -data = r.json() - -# Format dict and load into df -data = json.dumps(data["data"][0], indent=2, sort_keys=False, ensure_ascii=False) -df = pd.DataFrame.from_dict(json.loads(data), orient="index") - -# Add id for each drug for rasa -id = [] -for x in range(0, len(df)): - id.append(x) -df["id"] = id - -# Write to JSON file -with open("tripsit/getAllDrugs.json", "w") as fp: - # Clean NaN values - clean_data = { - k1: {k: v for k, v in v1.items() if v == v and v is not None} - for k1, v1 in df.to_dict("index").items() - } - # Set ensure_ascii to false to ensure we can keep greek letters (like alpha) - fp.write(json.dumps(clean_data, indent=2, ensure_ascii=False)) diff --git a/ts_pn_data/_cached_pw_substances.json b/ts_pn_data/_cached_pw_substances.json new file mode 100644 index 0000000..8850752 --- /dev/null +++ b/ts_pn_data/_cached_pw_substances.json @@ -0,0 +1,22162 @@ +[ + { + "url": "https://psychonautwiki.org/wiki/1,4-Butanediol", + "name": "1,4-Butanediol", + "aliases": [ + "1,4-B", + "BD", + "BDO", + "Butylene Glycol", + "One Comma Four", + "One Four Bee", + "or One Four B-D-O" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mL" + }, + { + "name": "Light", + "value": "0.5 - 1 mL" + }, + { + "name": "Common", + "value": "1 - 2.5 mL" + }, + { + "name": "Strong", + "value": "2.5 - 4 mL" + }, + { + "name": "Heavy", + "value": "4 mL +", + "note": "Warning: Doses above 4 mL can induce heavy sleep and doses above 6 mL can lead to poisoning" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "20 minutes - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Diol", + "Alkanediol" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within several weeks of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/1B-LSD", + "name": "1B-LSD", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 \u00b5g" + }, + { + "name": "Light", + "value": "25 - 75 \u00b5g" + }, + { + "name": "Common", + "value": "75 - 150 \u00b5g" + }, + { + "name": "Strong", + "value": "150 - 300 \u00b5g" + }, + { + "name": "Heavy", + "value": "300 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "extremely low toxicity relative to dose" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/1P-ETH-LAD", + "name": "1P-ETH-LAD", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 \u00b5g" + }, + { + "name": "Light", + "value": "30 - 60 \u00b5g" + }, + { + "name": "Common", + "value": "60 - 100 \u00b5g" + }, + { + "name": "Strong", + "value": "100 - 200 \u00b5g" + }, + { + "name": "Heavy", + "value": "200 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/1P-LSD", + "name": "1P-LSD", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 \u00b5g" + }, + { + "name": "Light", + "value": "25 - 75 \u00b5g" + }, + { + "name": "Common", + "value": "75 - 150 \u00b5g" + }, + { + "name": "Strong", + "value": "150 - 300 \u00b5g" + }, + { + "name": "Heavy", + "value": "300 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "extremely low toxicity relative to dose" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2-Aminoindane", + "name": "2-Aminoindane", + "aliases": [ + "2-AI" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Aminoindane" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2-FA", + "name": "2-FA", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 10 days" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2-FEA", + "name": "2-FEA", + "aliases": [], + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2.5 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2-FMA", + "name": "2-FMA", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 9 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 40 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "10 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2-Fluorodeschloroketamine", + "name": "2-Fluorodeschloroketamine", + "aliases": [ + "2-FDCK", + "2-FK", + "2-Fluoroketamine", + "Fluoroketamine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 140 mg" + }, + { + "name": "Heavy", + "value": "140 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 5.0 hours" + }, + { + "name": "Onset", + "value": "15 - 50 minutes" + }, + { + "name": "Peak", + "value": "50 - 100 minutes" + }, + { + "name": "After effects", + "value": "3 - 8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 45 mg" + }, + { + "name": "Common", + "value": "45 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 175 mg" + }, + { + "name": "Heavy", + "value": "175 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 3 hours" + }, + { + "name": "Onset", + "value": "1 - 3 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25B-NBOH", + "name": "25B-NBOH", + "aliases": [], + "roas": [], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25B-NBOMe", + "name": "25B-NBOMe", + "aliases": [], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "100 - 300 \u00b5g" + }, + { + "name": "Common", + "value": "300 - 500 \u00b5g" + }, + { + "name": "Strong", + "value": "500 - 700 \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "25B-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "25 \u00b5g" + }, + { + "name": "Light", + "value": "50 - 200 \u00b5g" + }, + { + "name": "Common", + "value": "200 - 350 \u00b5g" + }, + { + "name": "Strong", + "value": "350 - 500 \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "25B-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25C-NBOH", + "name": "25C-NBOH", + "aliases": [], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "100 \u00b5g" + }, + { + "name": "Light", + "value": "250 - 500 \u00b5g" + }, + { + "name": "Common", + "value": "500 - 750 \u00b5g" + }, + { + "name": "Strong", + "value": "750 - 1000 \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "25C-NBOH may be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "3 - 6 days" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25C-NBOMe", + "name": "25C-NBOMe", + "aliases": [ + "2C-C-NBOMe", + "Cimbi-82", + "NBOMe-2C-C" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "100 - 300 \u00b5g" + }, + { + "name": "Common", + "value": "300 - 700 \u00b5g" + }, + { + "name": "Strong", + "value": "700 - 1000 \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "25C-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 10 hours" + }, + { + "name": "Onset", + "value": "0 - 15 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "7 days", + "zero": "14 days" + }, + "toxicity": [ + "fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25D-NBOMe", + "name": "25D-NBOMe", + "aliases": [], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "300 \u00b5g" + }, + { + "name": "Light", + "value": "300 - 800 \u00b5g" + }, + { + "name": "Common", + "value": "800 - 1000 \u00b5g" + }, + { + "name": "Strong", + "value": "1000 - 1200 \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal at heavy doses.[4][5]" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "> 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal when insufflated.[4][5][6] It is strongly discouraged." + } + ], + "duration": null + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": [ + "psychedelics" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25I-NBOH", + "name": "25I-NBOH", + "aliases": [ + "25i-NBOH", + "Cimbi-27" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "200 - 500 \u00b5g" + }, + { + "name": "Common", + "value": "500 - 900 \u00b5g" + }, + { + "name": "Strong", + "value": "900 - 1400 \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "25I-NBOH may be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3.5 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2.5 hours" + }, + { + "name": "After effects", + "value": "3 - 12 days" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25I-NBOMe", + "name": "25I-NBOMe", + "aliases": [ + "25i", + "25i-NBOMe", + "Cimbi-5" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "200 - 500 \u00b5g" + }, + { + "name": "Common", + "value": "500 - 700 \u00b5g" + }, + { + "name": "Strong", + "value": "700 - 1000 \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "25I-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 120 minutes" + }, + { + "name": "Come up", + "value": "30 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "3 - 6 days" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "200 - 500 \u00b5g" + }, + { + "name": "Common", + "value": "500 - 700 \u00b5g" + }, + { + "name": "Strong", + "value": "700+ \u00b5g" + }, + { + "name": "Heavy", + "value": null, + "note": "25I-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 120 minutes" + }, + { + "name": "Offset", + "value": "120 - 180 minutes" + }, + { + "name": "After effects", + "value": "1 - 7 days" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/25N-NBOMe", + "name": "25N-NBOMe", + "aliases": [], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "< 100 \u00b5g" + }, + { + "name": "Light", + "value": "100 - 300 \u00b5g" + }, + { + "name": "Common", + "value": "300 - 800 \u00b5g" + }, + { + "name": "Strong", + "value": "800 - 1300 \u03bcg" + }, + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal at heavy doses.[4][5]" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "5 - 10 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal when insufflated.[4][5][6] It is strongly discouraged." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-B", + "name": "2C-B", + "aliases": [ + "Bees", + "Nexus", + "Tusi" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "40 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-B-FLY", + "name": "2C-B-FLY", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 18 mg" + }, + { + "name": "Strong", + "value": "18 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines", + "Substituted_benzofurans" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-C", + "name": "2C-C", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-D", + "name": "2C-D", + "aliases": [ + "2C-M", + "LE-25" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "0.5 - 1.5 hours" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-E", + "name": "2C-E", + "aliases": [ + "Aquarust", + "Eternity" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "1 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 7 mg" + }, + { + "name": "Strong", + "value": "7 - 14 mg" + }, + { + "name": "Heavy", + "value": "14 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 2 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-H", + "name": "2C-H", + "aliases": [ + "DMPEA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "??? -\u00a0???" + } + ], + "duration": [ + { + "name": "Total", + "value": "??? -\u00a0???" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3-5 days", + "zero": "7-10 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-I", + "name": "2C-I", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3-5 days", + "zero": "7-10 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-P", + "name": "2C-P", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 16 mg" + }, + { + "name": "Heavy", + "value": "16 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 20 hours" + }, + { + "name": "Onset", + "value": "1 - 3 hours" + }, + { + "name": "Come up", + "value": "2 - 4 hours" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "8 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "low potential for abuse and dependence", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-T", + "name": "2C-T", + "aliases": [ + "Tesseract" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 120 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + }, + { + "name": "Peak", + "value": "30 - 115 minutes" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "no negative health effects attributed to trying this drug" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-T-2", + "name": "2C-T-2", + "aliases": [ + "Rosy" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "25 - 30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 25 mg" + }, + { + "name": "Heavy", + "value": "25+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "no negative health effects attributed to trying this drug" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-T-21", + "name": "2C-T-21", + "aliases": [ + "Aurora" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 12 hours" + }, + { + "name": "Onset", + "value": "90 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2C-T-7", + "name": "2C-T-7", + "aliases": [ + "7th Heaven", + "Beautiful", + "Blue Mystic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "60 - 90 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 - 25 mg", + "note": "2C-T-7 has been fatal when insufflated at heavy doses of 30mg or higher." + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/2M2B", + "name": "2M2B", + "aliases": [ + "2-methyl-2-butanol", + "2m2b" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mL" + }, + { + "name": "Light", + "value": "1 - 5 mL" + }, + { + "name": "Common", + "value": "5 - 10 mL" + }, + { + "name": "Strong", + "value": "10 - 15 mL" + }, + { + "name": "Heavy", + "value": "15 mL +", + "note": "There have been unconsciousness and deaths reported at as low as 18 mL respective 29 mL." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "10 - 50 minutes" + }, + { + "name": "Peak", + "value": "6 - 8 hours" + }, + { + "name": "Offset", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Alcohol" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "GABA", + "depressants" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3,4-CTMP", + "name": "3,4-CTMP", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 2 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 18 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-FA", + "name": "3-FA", + "aliases": [ + "PAL-353" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 10 days" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-FEA", + "name": "3-FEA", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 60 mg" + }, + { + "name": "Strong", + "value": "50 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "2 - 3 days", + "zero": "3-7 days" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "serotonin|serotonergic", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-FMA", + "name": "3-FMA", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 10 days" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "serotonin|serotonergic", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-FPM", + "name": "3-FPM", + "aliases": [ + "PAL-593" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "30 - 90 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "5 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Phenylmorpholine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-HO-PCE", + "name": "3-HO-PCE", + "aliases": [ + "Hydroxyeticyclidine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +", + "note": "Redosing may result in dangerous cumulative effects." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "4 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a moderate potential for adverse side effects such as psychosis", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-HO-PCP", + "name": "3-HO-PCP", + "aliases": [ + "Hydroxyphencyclidine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 6 mg" + }, + { + "name": "Strong", + "value": "6 - 8 mg" + }, + { + "name": "Heavy", + "value": "8 mg +", + "note": "Redosing may result in dangerous cumulative effects." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Come up", + "value": "60 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "4 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for adverse side effects such as psychosis", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-MMC", + "name": "3-MMC", + "aliases": [ + "Metaphedrone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "50 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 350 mg" + }, + { + "name": "Heavy", + "value": "350 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 120 mg" + }, + { + "name": "Heavy", + "value": "120 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 4.5 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "10 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 1.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 1.5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-MeO-PCE", + "name": "3-MeO-PCE", + "aliases": [ + "Methoxyeticyclidine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25+ mg", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "3 - 15 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "45 - 60 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", + "crossTolerances": [ + "dissociatives" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3-MeO-PCP", + "name": "3-MeO-PCP", + "aliases": [ + "3-MeO" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "45 - 120 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "45 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "45 - 60 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "produces dependence with chronic use and has a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/3C-E", + "name": "3C-E", + "aliases": [ + "3C-Escaline" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "30 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 16 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "3 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 7 hours" + }, + { + "name": "Offset", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "3 - 5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-AcO-DET", + "name": "4-AcO-DET", + "aliases": [ + "4-Acetoxy-DET", + "Ethacetin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 1.5 hours" + }, + { + "name": "Peak", + "value": "1.5 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-AcO-DMT", + "name": "4-AcO-DMT", + "aliases": [ + "4-Acetoxy-DMT", + "O-Acetylpsilocin", + "Psilacetin", + "Synthetic mushrooms" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "7.5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 75 minutes" + }, + { + "name": "Peak", + "value": "2 - 3.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 25 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 hours - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": null, + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with low potential for abuse", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-AcO-DiPT", + "name": "4-AcO-DiPT", + "aliases": [ + "4-Acetoxy-DiPT", + "Aces", + "Ipracetin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-AcO-MET", + "name": "4-AcO-MET", + "aliases": [ + "4-Acetoxy-MET", + "Metacetin", + "O-Acetylmetocin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-AcO-MiPT", + "name": "4-AcO-MiPT", + "aliases": [ + "Mipracetin", + "O-Acetylmiprocin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "1.5 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-FA", + "name": "4-FA", + "aliases": [ + "4-FMP", + "Flux", + "PAL-303" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "40 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 130 mg" + }, + { + "name": "Strong", + "value": "130 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + }, + { + "name": "Come up", + "value": "30 - 75 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 3.5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulants" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-FMA", + "name": "4-FMA", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 75 mg" + }, + { + "name": "Strong", + "value": "100 - 125 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "3 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-HO-DET", + "name": "4-HO-DET", + "aliases": [ + "CZ-74", + "Ethocin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 3.5 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-HO-DPT", + "name": "4-HO-DPT", + "aliases": [ + "Procin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 90 mg" + }, + { + "name": "Strong", + "value": "90 - 130 mg" + }, + { + "name": "Heavy", + "value": "130 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 60 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 45 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-HO-DiPT", + "name": "4-HO-DiPT", + "aliases": [ + "Iprocin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "3 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-HO-EPT", + "name": "4-HO-EPT", + "aliases": [ + "Eprocin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "25 - 50 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-HO-MET", + "name": "4-HO-MET", + "aliases": [ + "Colour", + "Methylcybin", + "Metocin" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "25 - 45 minutes" + }, + { + "name": "Onset", + "value": "15 - 120 seconds" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-HO-MPT", + "name": "4-HO-MPT", + "aliases": [ + "Meprocin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-HO-MiPT", + "name": "4-HO-MiPT", + "aliases": [ + "Miprocin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4-MeO-PCP", + "name": "4-MeO-PCP", + "aliases": [ + "Methoxydine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "75 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 170 mg" + }, + { + "name": "Strong", + "value": "170 - 250 mg" + }, + { + "name": "Heavy", + "value": "250 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 20 hours" + }, + { + "name": "Onset", + "value": "45 - 120 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 7 hours" + }, + { + "name": "Offset", + "value": "6 - 10 hours" + }, + { + "name": "After effects", + "value": "6+ hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "30 - 75 mg" + }, + { + "name": "Common", + "value": "75 - 150 mg" + }, + { + "name": "Strong", + "value": "150mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 18 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "3 - 6 hours" + }, + { + "name": "Offset", + "value": "3 hours" + }, + { + "name": "After effects", + "value": "3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4F-EPH", + "name": "4F-EPH", + "aliases": [ + "4FEPH" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 25 minutes" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/4F-MPH", + "name": "4F-MPH", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "5 - 10 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 14 mg" + }, + { + "name": "Strong", + "value": "14 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-APB", + "name": "5-APB", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-Hydroxytryptophan", + "name": "5-Hydroxytryptophan", + "aliases": [ + "5-HTP", + "Cincofarm", + "Levothym", + "Levotonine", + "Oxitriptan", + "Oxyfan", + "Telesol", + "Tript-OH", + "and Triptum" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 300 mg" + }, + { + "name": "Strong", + "value": "300 - 500 mg" + }, + { + "name": "Heavy", + "value": "500 mg +" + } + ], + "duration": null + } + ], + "data": { + "class": { + "chemical": [ + "Amino_acid", + "Substituted_tryptamines" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-MAPB", + "name": "5-MAPB", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-MeO-DALT", + "name": "5-MeO-DALT", + "aliases": [ + "Foxtrot" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 20 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "Peak", + "value": "1 - 5 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "5 - 10 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "5 - 12 mg" + }, + { + "name": "Common", + "value": "12 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-MeO-DMT", + "name": "5-MeO-DMT", + "aliases": [ + "The God Molecule" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "20 - 40 minutes" + }, + { + "name": "Onset", + "value": "5 - 60 seconds" + }, + { + "name": "Come up", + "value": "30 - 60 seconds" + }, + { + "name": "Peak", + "value": "5 - 15 minutes" + }, + { + "name": "Offset", + "value": "10 - 20 minutes" + }, + { + "name": "After effects", + "value": "15 - 60 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "1 - 10 minutes" + }, + { + "name": "Peak", + "value": "10 - 40 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 hour", + "zero": "2 hours" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-MeO-DiBF", + "name": "5-MeO-DiBF", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "50 - 80 mg" + }, + { + "name": "Common", + "value": "80 - 110 mg" + }, + { + "name": "Strong", + "value": "110 - 140 mg" + }, + { + "name": "Heavy", + "value": "140 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_benzofurans" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-MeO-DiPT", + "name": "5-MeO-DiPT", + "aliases": [ + "Foxy", + "Foxy Methoxy" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "3 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/5-MeO-MiPT", + "name": "5-MeO-MiPT", + "aliases": [ + "Moxy" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "3 - 7 mg" + }, + { + "name": "Common", + "value": "7 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics", + "Entactogens" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/5F-AKB48", + "name": "5F-AKB48", + "aliases": [ + "5F-APINACA" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0 - 20 minutes" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "15 - 30 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Adamantanes", + "Indazolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "cannabinoids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/6-APB", + "name": "6-APB", + "aliases": [ + "Benzofury" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "30 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 90 mg" + }, + { + "name": "Strong", + "value": "90 - 120 mg" + }, + { + "name": "Heavy", + "value": "120 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics", + "Entactogens" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3-4 weeks", + "zero": "6-8 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/6-APDB", + "name": "6-APDB", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "30 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 130 mg" + }, + { + "name": "Heavy", + "value": "130 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines", + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "21-30 days", + "zero": "2-3 months" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/A-PHP", + "name": "A-PHP", + "aliases": [ + "PV7", + "alpha-PHP", + "\u03b1-PHP" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 8 minutes" + }, + { + "name": "Peak", + "value": "30 - 90 minutes" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 8 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 5 hours" + }, + { + "name": "After effects", + "value": "1 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "20 - 45 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Pyrrolidinophenone", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/A-PVP", + "name": "A-PVP", + "aliases": [ + "Flakka", + "O-2387", + "Prolintanone", + "alpha-PVP", + "\u03b1-PVP", + "\u03b2-ketone-prolintane" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "20 - 60 seconds" + }, + { + "name": "Peak", + "value": "3 - 6 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 5 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "20 - 45 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Pyrrolidinophenone", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/AB-FUBINACA", + "name": "AB-FUBINACA", + "aliases": [ + "Ab-fubi" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 1 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "0 - 20 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "10 - 20 minutes" + }, + { + "name": "After effects", + "value": "15 - 30 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Indazolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "cannabinoids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/AL-LAD", + "name": "AL-LAD", + "aliases": [ + "Aladdin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 \u00b5g" + }, + { + "name": "Light", + "value": "50 - 100 \u00b5g" + }, + { + "name": "Common", + "value": "100 - 225 \u00b5g" + }, + { + "name": "Strong", + "value": "225 - 350 \u00b5g" + }, + { + "name": "Heavy", + "value": "350 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 18 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "toxic dose is unknown", + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/ALD-52", + "name": "ALD-52", + "aliases": [ + "1-Acetyl-LSD", + "1A-LAD", + "1A-LSD", + "Orange Sunshine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 \u00b5g" + }, + { + "name": "Light", + "value": "30 - 100 \u00b5g" + }, + { + "name": "Common", + "value": "100 - 175 \u00b5g" + }, + { + "name": "Strong", + "value": "175 - 325 \u00b5g" + }, + { + "name": "Heavy", + "value": "325 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "toxic dose is unknown", + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/APICA", + "name": "APICA", + "aliases": [ + "2NE1", + "SDB-001" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Common", + "value": "1.5 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0 - 20 seconds" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "15 - 35 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Indole_cannabinoid", + "Indolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "cannabinoids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Acetylfentanyl", + "name": "Acetylfentanyl", + "aliases": [], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + }, + { + "name": "Onset", + "value": "7 - 10 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Anilidopiperidine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "unintentionally spilling a very small amount of acetylfentanyl on one's skin could result in a fatal overdose." + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Adrafinil", + "name": "Adrafinil", + "aliases": [ + "Olmifon" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100 mg" + }, + { + "name": "Light", + "value": "150 - 250 mg" + }, + { + "name": "Common", + "value": "250 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 600 mg" + }, + { + "name": "Heavy", + "value": "600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "45 - 60 minutes" + }, + { + "name": "Peak", + "value": "4.5 - 6 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": null, + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "not addictive with a low potential for abuse", + "crossTolerances": [ + "benzhydryl", + "nootropic|nootropics" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Allylescaline", + "name": "Allylescaline", + "aliases": [ + "AL" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "45 - 240 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Alpha-GPC", + "name": "Alpha-GPC", + "aliases": [ + "L-Alpha glycerylphosphorylcholine", + "alpha-GPC", + "choline alfoscerate" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 300 mg" + }, + { + "name": "Common", + "value": "300 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 1000 mg" + }, + { + "name": "Heavy", + "value": "1000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Choline_derivative" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "7 days", + "zero": "14 days" + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Alprazolam", + "name": "Alprazolam", + "aliases": [ + "Xanax" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Strong", + "value": "1.5 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 - 3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "2 - 6 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7-14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Amanita_muscaria", + "name": "Amanita muscaria", + "aliases": [ + "Fly agaric", + "Fly amanita" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Amphetamine", + "name": "Amphetamine", + "aliases": [ + "Adderall", + "Pep", + "Speed" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "7.5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 135 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "3 - 6 hours" + } + ], + "bioavailability": "75%+" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "6 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "has a high abuse potential and can cause dependence with chronic use", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Anadenanthera_peregrina", + "name": "Anadenanthera peregrina", + "aliases": [ + "Cohoba", + "Jopo", + "Yopo" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Aniracetam", + "name": "Aniracetam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "350 mg" + }, + { + "name": "Light", + "value": "500 - 1200 mg" + }, + { + "name": "Common", + "value": "1200 - 1800 mg" + }, + { + "name": "Strong", + "value": "1800 - 2400 mg" + }, + { + "name": "Heavy", + "value": "2400 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "45 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "non-addictive with a low potential for abuse", + "crossTolerances": [ + "racetam", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Armodafinil", + "name": "Armodafinil", + "aliases": [ + "Artvigil", + "Neoresotyl", + "Nuvigil", + "R-Modawake", + "Waklert" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 15 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2.5 hours" + }, + { + "name": "Peak", + "value": "4 - 7 hours" + }, + { + "name": "Offset", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzhydryl" + ], + "psychoactive": [ + "Eugeroic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "The median lethal dose at which 50% of participants die (LD50) from either armodafinil or modafinil for human beings has never been reached" + ], + "addictionPotential": "mildly addictive with a low potential for abuse", + "crossTolerances": [ + "benzhydryl", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Atropa_belladonna", + "name": "Atropa belladonna", + "aliases": [ + "Belladonna", + "Deadly nightshade" + ], + "roas": [], + "data": { + "class": { + "chemical": [ + "Substituted_tropanes" + ], + "psychoactive": [ + "Deliriant" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ayahuasca", + "name": "Ayahuasca", + "aliases": [ + "Aya", + "Caapi", + "Cip\u00f3", + "Hoasca", + "Natem", + "Shori", + "Vegetal", + "Yag\u00e9", + "Yaj\u00e9" + ], + "roas": [ + { + "name": "Oral", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": null, + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": [ + "LD50 is around 50 times a regular dose" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Banisteriopsis_caapi", + "name": "Banisteriopsis caapi", + "aliases": [ + "Ayahuasca", + "Caapi or Yag\u00e9" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Bromantane", + "name": "Bromantane", + "aliases": [ + "Bromantan", + "Ladasten" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "10 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + } + ], + "bioavailability": "42%" + } + ], + "data": { + "class": { + "chemical": [ + "Adamantanes" + ], + "psychoactive": null + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Bromo-DragonFLY", + "name": "Bromo-DragonFLY", + "aliases": [ + "B-DFLY", + "DOB-DragonFLY", + "Dragonfly" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 \u00b5g" + }, + { + "name": "Light", + "value": "100 - 300 \u00b5g" + }, + { + "name": "Common", + "value": "300 - 500 \u00b5g" + }, + { + "name": "Strong", + "value": "500 - 750 \u00b5g" + }, + { + "name": "Heavy", + "value": "750 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 days" + }, + { + "name": "Onset", + "value": "2 - 7 hours" + }, + { + "name": "Come up", + "value": "3 - 6 hours" + }, + { + "name": "Peak", + "value": "6 - 12 hours" + }, + { + "name": "Offset", + "value": "3 - 8 hours" + }, + { + "name": "After effects", + "value": "12 - 36 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "6 days", + "zero": "14 days" + }, + "toxicity": [ + "extreme vasoconstrictive effects", + "one can easily overdose if this substance is not measured correctly", + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Bufotenin", + "name": "Bufotenin", + "aliases": [ + "5-HO-DMT" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 90 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "Peak", + "value": "1 - 5 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "10 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 hour", + "zero": "2 hours" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Buprenorphine", + "name": "Buprenorphine", + "aliases": [ + "Addnok", + "Buprenex", + "Butrans", + "Cizdol", + "Subutex", + "Transtec" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "<0.3 mg" + }, + { + "name": "Light", + "value": "0.3 - 0.6 mg" + }, + { + "name": "Common", + "value": "0.6 - 1.3 mg" + }, + { + "name": "Strong", + "value": "1.3 - 2.4 mg" + }, + { + "name": "Heavy", + "value": "2.4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 18 hours" + }, + { + "name": "Onset", + "value": "40 - 80 minutes" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "After effects", + "value": "1 - 3 days" + } + ], + "bioavailability": "30%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.2 mg" + }, + { + "name": "Light", + "value": "0.2 - 0.4 mg" + }, + { + "name": "Common", + "value": "0.4 - 0.8 mg" + }, + { + "name": "Strong", + "value": "0.8 - 1.5 mg" + }, + { + "name": "Heavy", + "value": "1.5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "After effects", + "value": "1 - 3 days" + } + ], + "bioavailability": "48%" + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Butylone", + "name": "Butylone", + "aliases": [ + "B1", + "bk-MBDB" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 80 mg" + }, + { + "name": "Common", + "value": "80 - 125 mg" + }, + { + "name": "Strong", + "value": "125 - 225 mg" + }, + { + "name": "Heavy", + "value": "225 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "60 - 120 minutes" + }, + { + "name": "Offset", + "value": "60 - 120 minutes" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "MDxx", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Caffeine", + "name": "Caffeine", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 500 mg" + }, + { + "name": "Heavy", + "value": "500 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "10 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "6 - 10 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2.5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2.5 hours" + }, + { + "name": "Onset", + "value": "0.5 - 2 minutes" + }, + { + "name": "Come up", + "value": "0.5 - 2 minutes" + }, + { + "name": "Peak", + "value": "0.5 - 1 hours" + }, + { + "name": "Offset", + "value": "6 - 10 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Xanthines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "The LD50 of caffeine in humans is dependent on individual sensitivity, but is estimated to be about 150 to 200 milligrams per kilogram of body mass or roughly 80 to 100 cups of coffee for an average adult" + ], + "addictionPotential": "produces dependence with chronic use and has a low abuse potential", + "crossTolerances": [] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Cake", + "name": "Cake", + "aliases": [ + "Caky", + "Cokoo" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25g-30g" + }, + { + "name": "Light", + "value": "30g-65g" + }, + { + "name": "Common", + "value": "65g-100g" + }, + { + "name": "Strong", + "value": "100g-300g" + }, + { + "name": "Heavy", + "value": "300g-500g" + } + ], + "duration": null, + "bioavailability": "90%" + } + ], + "data": { + "class": { + "chemical": null, + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Cannabidiol", + "name": "Cannabidiol", + "aliases": [ + "CBD", + "Epidiolex" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 4 hours" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Cannabinoid" + ], + "psychoactive": null + }, + "tolerance": null, + "toxicity": [ + "well-tolerated and shows little to no toxicity" + ], + "addictionPotential": "low abuse potential", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Cannabis", + "name": "Cannabis", + "aliases": [ + "Bud", + "Grass", + "Green", + "Herb", + "Marijuana", + "Mary Jane", + "Pot", + "Tree", + "Weed" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "33 - 66 mg" + }, + { + "name": "Common", + "value": "66 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "0 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "45 - 180 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg (THC)" + }, + { + "name": "Light", + "value": "2.5 - 5 mg (THC)" + }, + { + "name": "Common", + "value": "5 - 10 mg (THC)" + }, + { + "name": "Strong", + "value": "10 - 25 mg (THC)" + }, + { + "name": "Heavy", + "value": "25 mg + (THC)" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 120 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Cannabinoid" + ], + "psychoactive": null + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "1 - 2 weeks", + "zero": "2 - 3 weeks" + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "moderately habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Carisoprodol", + "name": "Carisoprodol", + "aliases": [ + "Soma" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 325 mg" + }, + { + "name": "Common", + "value": "325 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 750 mg" + }, + { + "name": "Heavy", + "value": "750 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "1 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Carbamate" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": null, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Choline_bitartrate", + "name": "Choline bitartrate", + "aliases": [ + "Choline" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 250 mg" + }, + { + "name": "Common", + "value": "250 - 1000 mg" + }, + { + "name": "Strong", + "value": "1000 - 2000 mg" + }, + { + "name": "Heavy", + "value": "2000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 8 hours" + } + ], + "bioavailability": "40%" + } + ], + "data": { + "class": { + "chemical": [ + "Ammonium_salt" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "7 days", + "zero": "14 days" + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Citicoline", + "name": "Citicoline", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 250 mg" + }, + { + "name": "Common", + "value": "250 - 1000 mg" + }, + { + "name": "Strong", + "value": "1000 - 2000 mg" + }, + { + "name": "Heavy", + "value": "2000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "58 - 74 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "2.5 - 3.5 hours" + }, + { + "name": "Offset", + "value": "30 - 40 hours" + }, + { + "name": "After effects", + "value": "40 - 60 hours" + } + ], + "bioavailability": "98%" + } + ], + "data": { + "class": { + "chemical": [ + "Ammonium_salt" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": null, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Clonazepam", + "name": "Clonazepam", + "aliases": [ + "K-Pins", + "Klonopin", + "Rivotril" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1 mg" + }, + { + "name": "Strong", + "value": "1 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "After effects", + "value": "8 - 48 hours" + } + ], + "bioavailability": "90%" + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Clonazolam", + "name": "Clonazolam", + "aliases": [ + "Clonitrazolam" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "75 - 200 \u00b5g" + }, + { + "name": "Common", + "value": "200 - 400 \u00b5g" + }, + { + "name": "Strong", + "value": "400 - 1 mg" + }, + { + "name": "Heavy", + "value": "1 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Clonidine", + "name": "Clonidine", + "aliases": [ + "Catapres", + "Catapres-TTS", + "Kapvay", + "Nexiclon XR" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 \u03bcg" + }, + { + "name": "Light", + "value": "50 - 75 \u03bcg" + }, + { + "name": "Common", + "value": "75 - 100 \u03bcg" + }, + { + "name": "Strong", + "value": "100 - 300 \u03bcg" + }, + { + "name": "Heavy", + "value": "300 \u03bcg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "6 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Imidazoline" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": "not addictive and has a low potential for abuse", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Cocaine", + "name": "Cocaine", + "aliases": [ + "Blow", + "Coke", + "Crack", + "Girl", + "Nose Candy", + "Snow", + "White" + ], + "roas": [ + { + "name": "Inhaled", + "dosage": null, + "duration": null + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 90 minutes" + }, + { + "name": "Onset", + "value": "1 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 15 minutes" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "10 - 30 minutes" + } + ], + "bioavailability": "60-80%" + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tropanes" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "individuals have died from as little as 30 mg applied to mucous membranes, whereas addicts may tolerate up to 5 grams daily" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Codeine", + "name": "Codeine", + "aliases": [], + "roas": [ + { + "name": "Smoked", + "dosage": null, + "duration": null, + "bioavailability": "49.9 - 59.7%" + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Coluracetam", + "name": "Coluracetam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "not addictive with a low potential for abuse", + "crossTolerances": [ + "racetam", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Creatine", + "name": "Creatine", + "aliases": [ + "Methylguanidoacetic acid", + "N-Carbamimidoyl-N-methylglycine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 g" + }, + { + "name": "Light", + "value": "1 - 5 g" + }, + { + "name": "Common", + "value": "5 - 10 g" + }, + { + "name": "Strong", + "value": "10 - 20 g" + }, + { + "name": "Heavy", + "value": "20 g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 36 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Nitrogenous_organic_acid" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": "not habit-forming with a low potential for abuse", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Cyclazodone", + "name": "Cyclazodone", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +", + "note": "Liver damage may result from heavy or sustained usage." + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "4-oxazolidinone", + "Substituted_aminorexes" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": null, + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DET", + "name": "DET", + "aliases": [ + "Diethyltryptamine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "2 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DMT", + "name": "DMT", + "aliases": [ + "Dmitry", + "N,N-DMT", + "The Glory", + "The Spirit Molecule" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 20 minutes" + }, + { + "name": "Onset", + "value": "20 - 40 seconds" + }, + { + "name": "Come up", + "value": "1 - 3 minutes" + }, + { + "name": "Peak", + "value": "2 - 8 minutes" + }, + { + "name": "Offset", + "value": "1 - 6 minutes" + }, + { + "name": "After effects", + "value": "10 - 60 minutes" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "4 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 30 minutes" + }, + { + "name": "Onset", + "value": "2 - 10 seconds" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "2 - 5 minutes" + }, + { + "name": "Offset", + "value": "-" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "does not appear to occur", + "half": null, + "zero": null + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "crossTolerances": [ + "psychedelics" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DOB", + "name": "DOB", + "aliases": [ + "Brolamfetamine", + "Bromo-DMA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.2 mg" + }, + { + "name": "Light", + "value": "0.2 - 0.75 mg" + }, + { + "name": "Common", + "value": "0.75 - 1.75 mg" + }, + { + "name": "Strong", + "value": "1.75 - 3 mg" + }, + { + "name": "Heavy", + "value": "3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "14 - 24 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "2 - 4 hours" + }, + { + "name": "Peak", + "value": "6 - 10 hours" + }, + { + "name": "Offset", + "value": "4 - 8 hours" + }, + { + "name": "After effects", + "value": "4 - 16 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "4-7 days", + "zero": "7-10 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DOC", + "name": "DOC", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 24 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "6 - 12 hours" + }, + { + "name": "Offset", + "value": "2 - 8 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.25 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 3.5 mg" + }, + { + "name": "Heavy", + "value": "3.5 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 8 hours" + }, + { + "name": "After effects", + "value": "2 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DOI", + "name": "DOI", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 3 mg" + }, + { + "name": "Heavy", + "value": "3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "16 - 24 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "6 - 10 hours" + }, + { + "name": "Offset", + "value": "4 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "10-14 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DOM", + "name": "DOM", + "aliases": [ + "STP (Serenity", + "Tranquility", + "and Peace)" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 3 mg" + }, + { + "name": "Common", + "value": "3 - 5 mg" + }, + { + "name": "Strong", + "value": "5 - 10 mg" + }, + { + "name": "Heavy", + "value": "10 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 16 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "6 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "4 - 16 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DPT", + "name": "DPT", + "aliases": [ + "Dipropyltryptamine", + "The Light" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "15 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 90 minutes" + }, + { + "name": "Onset", + "value": "0 - 1 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "75 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 350 mg" + }, + { + "name": "Heavy", + "value": "350 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "After effects", + "value": "2 - 3 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "20 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "Peak", + "value": "30 - 46 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Datura", + "name": "Datura", + "aliases": [ + "Jimson Weed" + ], + "roas": [ + { + "name": "Oral", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "8 - 18 hours" + }, + { + "name": "Onset", + "value": "20 - 120 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "5 - 12 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": null, + "psychoactive": [ + "Deliriant" + ] + }, + "tolerance": { + "full": "with repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "mildly addictive with a high potential for adverse side effects such as psychosis", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Datura_(botany)", + "name": "Datura (botany)", + "aliases": [ + "Jimsonweed", + "angel's trumpets", + "devil's trumpets", + "devil's weed", + "hell's bells", + "moonflowers", + "thorn-apple" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Deschloroetizolam", + "name": "Deschloroetizolam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 6 mg" + }, + { + "name": "Strong", + "value": "6 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 10 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "3 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Thienodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepine", + "thienodiazepine" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Deschloroketamine", + "name": "Deschloroketamine", + "aliases": [ + "DCK", + "DXE", + "O-PCM" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 90 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "3 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "3 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Desomorphine", + "name": "Desomorphine", + "aliases": [ + "Krok", + "Krokodil" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Desoxypipradrol", + "name": "Desoxypipradrol", + "aliases": [ + "2-DPMP", + "Desoxypipradol", + "Ivory Wave" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 6 mg" + }, + { + "name": "Strong", + "value": "6 - 8 mg" + }, + { + "name": "Heavy", + "value": "8 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "16 - 72 hours" + }, + { + "name": "Onset", + "value": "1 - 4 hours" + }, + { + "name": "Peak", + "value": "9 - 30 hours" + }, + { + "name": "Offset", + "value": "6 - 40 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Common", + "value": "1.5 - 3.5 mg" + }, + { + "name": "Strong", + "value": "3.5 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 72 hours" + }, + { + "name": "Onset", + "value": "15 - 240 minutes" + }, + { + "name": "Come up", + "value": "2 - 6 hours" + }, + { + "name": "Peak", + "value": "6 - 30 hours" + }, + { + "name": "Offset", + "value": "6 - 40 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_piperidines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Dextromethorphan", + "name": "Dextromethorphan", + "aliases": [ + "DM", + "DMO", + "DXM", + "Delsym", + "Dex", + "DexAlone", + "Duract", + "Robitussin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 mg" + }, + { + "name": "Light", + "value": "100 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 700 mg" + }, + { + "name": "Heavy", + "value": "700 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 120 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "produces dependence with chronic use and has moderate abuse potential", + "crossTolerances": [ + "dissociatives" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Dextropropoxyphene", + "name": "Dextropropoxyphene", + "aliases": [ + "Darvon", + "propoxyphene" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "30 - 65 mg" + }, + { + "name": "Common", + "value": "65 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 6 hours" + } + ], + "bioavailability": "40%" + } + ], + "data": { + "class": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "high toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "known to cause potentially fatal heart arrhythmias" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/DiPT", + "name": "DiPT", + "aliases": [], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 60 minutes" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 75 mg" + }, + { + "name": "Strong", + "value": "75 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Diazepam", + "name": "Diazepam", + "aliases": [ + "Apaurin", + "Diastat", + "Mother's Little Helper", + "Valium" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2.5 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "After effects", + "value": "12 - 36 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7-14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Dichloropane", + "name": "Dichloropane", + "aliases": [ + "RTI-111" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2.5 mg" + }, + { + "name": "Light", + "value": "2.5 - 7.5 mg" + }, + { + "name": "Common", + "value": "7.5 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "40 - 75 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "Come up", + "value": "15 - 60 seconds" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "20 - 40 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tropanes" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "2 - 4 days", + "zero": "1 - 1.5 weeks" + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Diclazepam", + "name": "Diclazepam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "10 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within 3-4 days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "GABAergic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Dihydrocodeine", + "name": "Dihydrocodeine", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Diphenhydramine", + "name": "Diphenhydramine", + "aliases": [ + "Benadryl", + "DPH", + "Nytol", + "Sominex", + "Unisom SleepMelts", + "ZzzQuil" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "100 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 700 mg" + }, + { + "name": "Heavy", + "value": "700 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 6 hours" + }, + { + "name": "After effects", + "value": "up to 24 hours" + } + ], + "bioavailability": "40-60%" + } + ], + "data": { + "class": { + "chemical": [ + "Ethanolamine" + ], + "psychoactive": [ + "Deliriant", + "Depressant" + ] + }, + "tolerance": { + "full": "with repeated use", + "half": null, + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "fatal at amounts close to or exceeding 2 grams" + ], + "addictionPotential": "produces dependence with chronic use", + "crossTolerances": [ + "deliriant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Diphenidine", + "name": "Diphenidine", + "aliases": [], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "?? mg", + "note": "\"??\" is not a number." + }, + { + "name": "Light", + "value": "?? - 20 mg", + "note": "\"??\" is not a number." + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 55 mg" + }, + { + "name": "Heavy", + "value": "> 55 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 3 hours" + }, + { + "name": "Onset", + "value": "30 - 90 seconds" + }, + { + "name": "Peak", + "value": "0.5 - 2 hours" + }, + { + "name": "Offset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "2 - 5 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "40 - 65 mg" + }, + { + "name": "Common", + "value": "65 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 130 mg" + }, + { + "name": "Heavy", + "value": "> 130 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "4 - 24 Hours" + } + ] + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Diarylethylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/EPT", + "name": "EPT", + "aliases": [], + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 110 mg" + }, + { + "name": "Heavy", + "value": "110 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "does not produce dependence and has low abuse potential", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/ETH-CAT", + "name": "ETH-CAT", + "aliases": [ + "Ethcathinone", + "Ethylpropion" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "60 mg" + }, + { + "name": "Light", + "value": "100 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 225 mg" + }, + { + "name": "Strong", + "value": "225 - 325 mg" + }, + { + "name": "Heavy", + "value": "325 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 120 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "2 - 3 days", + "zero": "3-5 days" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "mildly addictive with a comparatively low potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/ETH-LAD", + "name": "ETH-LAD", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 \u00b5g" + }, + { + "name": "Light", + "value": "30 - 60 \u00b5g" + }, + { + "name": "Common", + "value": "60 - 150 \u00b5g" + }, + { + "name": "Strong", + "value": "150 - 225 \u00b5g" + }, + { + "name": "Heavy", + "value": "225 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "8 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Efavirenz", + "name": "Efavirenz", + "aliases": [ + "Sustiva" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Common", + "value": "600 - 1800 mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ], + "bioavailability": "50%" + } + ], + "data": { + "class": { + "chemical": [ + "Benzoxazine" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": [ + "low toxicity", + "may cause liver toxicity at high doses or after chronic use" + ], + "addictionPotential": "not known to be habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ephenidine", + "name": "Ephenidine", + "aliases": [ + "NEDPA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "30 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Diarylethylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ephylone", + "name": "Ephylone", + "aliases": [ + "bk-EBDP", + "bk-ethyl-K", + "\u03b2k-EBDP" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 80 mg" + }, + { + "name": "Heavy", + "value": null, + "note": "Ephylone may be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": null, + "zero": null + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Escaline", + "name": "Escaline", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "30 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "90 - 120 minutes" + }, + { + "name": "After effects", + "value": "3 - 5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ethylmorphine", + "name": "Ethylmorphine", + "aliases": [ + "codethyline", + "dionine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "very addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ethylone", + "name": "Ethylone", + "aliases": [ + "MDEC", + "bk-MDEA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 mg" + }, + { + "name": "Light", + "value": "75 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 225 mg" + }, + { + "name": "Strong", + "value": "225 - 325 mg" + }, + { + "name": "Heavy", + "value": "325 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 120 minutes" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": null, + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ethylphenidate", + "name": "Ethylphenidate", + "aliases": [ + "EPH" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 120 mg" + }, + { + "name": "Heavy", + "value": "120 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "40 - 120 minutes" + } + ] + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopaminergic", + "stimulants" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Etizolam", + "name": "Etizolam", + "aliases": [ + "Etilaam", + "Etizest" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.2 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2.5 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ], + "bioavailability": "93%" + } + ], + "data": { + "class": { + "chemical": [ + "Thienodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "crossTolerances": [ + "benzodiazepine", + "thienodiazepine" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/F-Phenibut", + "name": "F-Phenibut", + "aliases": [ + "Fluorobut", + "Fluorophenibut" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 600 mg" + }, + { + "name": "Heavy", + "value": "600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Gabapentinoids" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids", + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "crossTolerances": [ + "GABA" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Fentanyl", + "name": "Fentanyl", + "aliases": [ + "Abstral", + "Actiq", + "Duragesic", + "Durogesic", + "Fentora", + "Haldid", + "Instanyl", + "Lazanda", + "Matrifen", + "Onsolis", + "Sublimaze", + "fentanil" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "5 - 10 \u03bcg" + }, + { + "name": "Light", + "value": "10 - 25 \u03bcg" + }, + { + "name": "Common", + "value": "25 - 50 \u03bcg" + }, + { + "name": "Strong", + "value": "50 - 75 \u03bcg" + }, + { + "name": "Heavy", + "value": "75 \u03bcg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + } + ], + "bioavailability": "50%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 - 10 \u03bcg" + }, + { + "name": "Light", + "value": "10 - 25 \u03bcg" + }, + { + "name": "Common", + "value": "25 - 50 \u03bcg" + }, + { + "name": "Strong", + "value": "50 - 75 \u03bcg" + }, + { + "name": "Heavy", + "value": "75 \u03bcg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + } + ], + "bioavailability": "89%" + }, + { + "name": "Transdermal", + "dosage": [ + { + "name": "Threshold", + "value": "5 - 12 \u03bcg" + }, + { + "name": "Light", + "value": "12 - 25 \u03bcg" + }, + { + "name": "Common", + "value": "25 - 50 \u03bcg" + }, + { + "name": "Strong", + "value": "50 - 100 \u03bcg" + }, + { + "name": "Heavy", + "value": "100 \u03bcg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "48 - 72 hours" + }, + { + "name": "Onset", + "value": "2 - 4 hours" + } + ], + "bioavailability": "92%" + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_piperidines", + "Anilidopiperidine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "unintentionally transporting the substance from the skin by touching the mouth, nose or eyes is dangerous" + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Flubromazepam", + "name": "Flubromazepam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 - 16 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "40 - 90 minutes" + }, + { + "name": "After effects", + "value": "24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Flubromazolam", + "name": "Flubromazolam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u03bcg" + }, + { + "name": "Light", + "value": "100 - 150 \u03bcg" + }, + { + "name": "Common", + "value": "150 - 250 \u03bcg" + }, + { + "name": "Strong", + "value": "250 - 400 \u03bcg" + }, + { + "name": "Heavy", + "value": "400 \u03bcg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 18 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "24 hours +" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/GBL", + "name": "GBL", + "aliases": [ + "gamma-Butyrolactone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.3 ml" + }, + { + "name": "Light", + "value": "0.3 - 0.9 ml" + }, + { + "name": "Common", + "value": "0.9 - 1.5 ml" + }, + { + "name": "Strong", + "value": "1.5 - 3 ml", + "note": "Warning: Doses over 2 ml can induce heavy sleep." + }, + { + "name": "Heavy", + "value": "3+ ml" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "3 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 15 minutes" + }, + { + "name": "Peak", + "value": "30 - 45 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Tetrahydrofuran" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within several days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": null, + "addictionPotential": "highly physically and moderately to highly psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/GHB", + "name": "GHB", + "aliases": [ + "G", + "Sodium oxybate", + "Xyrem" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 g" + }, + { + "name": "Light", + "value": "0.5 - 1 g" + }, + { + "name": "Common", + "value": "1 - 2.5 g" + }, + { + "name": "Strong", + "value": "2.5 - 4 g" + }, + { + "name": "Heavy", + "value": "4 g +", + "note": "Warning: Risk of death above 10 g" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Come up", + "value": "10 - 20 minutes" + }, + { + "name": "Peak", + "value": "45 - 90 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Butyric_acid" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within several days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "Doses above 10 grams are associated with a risk of death", + "considered to be a safe and non-toxic substance when used responsibly or medically" + ], + "addictionPotential": "moderately to highly physically and moderately psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Gabapentin", + "name": "Gabapentin", + "aliases": [ + "Gabarone", + "Gralise", + "Neurontin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "200 mg" + }, + { + "name": "Light", + "value": "200 - 600 mg" + }, + { + "name": "Common", + "value": "600 - 900 mg" + }, + { + "name": "Strong", + "value": "900 - 1200 mg" + }, + { + "name": "Heavy", + "value": "1200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ], + "bioavailability": "27% - 60%" + } + ], + "data": { + "class": { + "chemical": [ + "Gabapentinoids" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "with prolonged continuous usage", + "half": null, + "zero": "7-14 days" + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Galantamine", + "name": "Galantamine", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 16 mg" + }, + { + "name": "Strong", + "value": "16 - 24 mg" + }, + { + "name": "Heavy", + "value": "24 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + } + ], + "bioavailability": "90%" + } + ], + "data": { + "class": { + "chemical": [ + "Benzazepine" + ], + "psychoactive": [ + "Sedative", + "Oneirogen" + ] + }, + "tolerance": null, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Haloperidol", + "name": "Haloperidol", + "aliases": [ + "Haldol" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.25 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 5 mg" + }, + { + "name": "Strong", + "value": "5 - 10 mg" + }, + { + "name": "Heavy", + "value": "10 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 36 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ], + "bioavailability": "60-70%" + } + ], + "data": { + "class": { + "chemical": [ + "Butyrophenone", + "Substituted_piperidines" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "tolerance": null, + "toxicity": [ + "can have serious side effects at higher dosages", + "risk of having severe extrapyramidal symptoms and muscle rigidity" + ], + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Heroin", + "name": "Heroin", + "aliases": [ + "Brown", + "H", + "Junk", + "Smack" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 10 seconds" + }, + { + "name": "Come up", + "value": "5 - 10 seconds" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "10 - 30 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "7.5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "10 - 60 seconds" + }, + { + "name": "Come up", + "value": "10 - 60 seconds" + }, + { + "name": "Peak", + "value": "1 - 90 minutes" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "1.5 - 3 hours" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Common", + "value": "5 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 5 hours" + }, + { + "name": "Onset", + "value": "0 - 5 seconds" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "Offset", + "value": "-" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Hexedrone", + "name": "Hexedrone", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "50 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 125 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "1 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": null, + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Hydrocodone", + "name": "Hydrocodone", + "aliases": [ + "Vicodin (with paracetamol)", + "Zohydro ER (extended-release)" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "10 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "with prolonged use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "moderately addictive", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Hydromorphone", + "name": "Hydromorphone", + "aliases": [ + "Dilaudid", + "Jurnista", + "Palladone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 8 mg" + }, + { + "name": "Heavy", + "value": "8 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10 - 90 seconds" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Hyoscyamus_niger_(botany)", + "name": "Hyoscyamus niger (botany)", + "aliases": [ + "Henbane", + "Stinking nightshade" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ibogaine", + "name": "Ibogaine", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "15 - 22 mg/kg of body weight" + }, + { + "name": "Strong", + "value": null, + "note": "Strong doses may result in fatal heart complications." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30 - 180 minutes" + }, + { + "name": "Peak", + "value": "18 - 36 hours" + }, + { + "name": "After effects", + "value": "24 - 72 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Isopropylphenidate", + "name": "Isopropylphenidate", + "aliases": [ + "IPH", + "IPPH" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3.5 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/JWH-073", + "name": "JWH-073", + "aliases": [ + "Spice" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 3 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "60 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Naphthoylindole" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "cannabinoids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Ketamine", + "name": "Ketamine", + "aliases": [ + "Cat Tranquilizer", + "K", + "Ket", + "Ketalar", + "Ketanest", + "Ketaset", + "Kitty", + "Special K" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 300 mg" + }, + { + "name": "Strong", + "value": "300 - 450 mg" + }, + { + "name": "Heavy", + "value": "450 mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "5 - 20 minutes" + }, + { + "name": "Peak", + "value": "45 - 90 minutes" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "4 - 8 hours" + } + ], + "bioavailability": "17%" + }, + { + "name": "Sublingual", + "dosage": null, + "duration": null, + "bioavailability": "20% - 29%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 75 mg" + }, + { + "name": "Strong", + "value": "75 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 1.5 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ], + "bioavailability": "45%" + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderate to high abuse potential and produces psychological dependence with chronic use", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Kratom", + "name": "Kratom", + "aliases": [ + "Mitragyna speciosa", + "ketum", + "kratom or kratum", + "\u0e01\u0e23\u0e30\u0e17\u0e48\u0e2d\u0e21 (Thai)" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 g" + }, + { + "name": "Light", + "value": "2 - 3 g" + }, + { + "name": "Common", + "value": "3 - 5 g" + }, + { + "name": "Strong", + "value": "5 - 8 g" + }, + { + "name": "Heavy", + "value": "8 g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Indole_alkaloids" + ], + "psychoactive": [ + "Stimulants", + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": "produces dependence with chronic use and has a high abuse potential", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/LSA", + "name": "LSA", + "aliases": [ + "Ergine" + ], + "roas": [], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": null, + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/LSD", + "name": "LSD", + "aliases": [ + "Acid", + "Blotter", + "Cid", + "L", + "LSD-25", + "Lucy", + "Tabs" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "15 \u00b5g" + }, + { + "name": "Light", + "value": "25 - 75 \u00b5g" + }, + { + "name": "Common", + "value": "75 - 150 \u00b5g" + }, + { + "name": "Strong", + "value": "150 - 300 \u00b5g" + }, + { + "name": "Heavy", + "value": "300 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "12 - 48 hours" + } + ], + "bioavailability": "71% - 71%" + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": null, + "zero": "7 days" + }, + "toxicity": [ + "extremely low toxicity relative to dose" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "crossTolerances": [ + "psychedelics" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/LSM-775", + "name": "LSM-775", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "250 \u00b5g" + }, + { + "name": "Light", + "value": "500 - 750 \u00b5g" + }, + { + "name": "Common", + "value": "750 - 1250 \u00b5g" + }, + { + "name": "Strong", + "value": "1250 - 1500 \u00b5g" + }, + { + "name": "Heavy", + "value": "1500 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelics" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/LSZ", + "name": "LSZ", + "aliases": [ + "Diazedine", + "LA-SS-Az", + "Lambda" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "100 - 150 \u00b5g" + }, + { + "name": "Common", + "value": "150 - 300 \u00b5g" + }, + { + "name": "Strong", + "value": "300 - 400 \u00b5g" + }, + { + "name": "Heavy", + "value": "400 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Lisdexamfetamine", + "name": "Lisdexamfetamine", + "aliases": [ + "Elvanse", + "Vyvanse" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 14 hours" + }, + { + "name": "Onset", + "value": "60 - 90 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Lorazepam", + "name": "Lorazepam", + "aliases": [ + "Ativan", + "Lorsilan", + "Orfidal" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Strong", + "value": "1.5 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 - 3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MCPP", + "name": "MCPP", + "aliases": [ + "mCPP" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 120 mg" + }, + { + "name": "Strong", + "value": "120 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "3 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_piperazines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/MDA", + "name": "MDA", + "aliases": [ + "Sally", + "Sass", + "Tenamfetamine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 145 mg" + }, + { + "name": "Heavy", + "value": "145 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics", + "Entactogens" + ] + }, + "tolerance": { + "full": "repeated and heavy usage", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "psychedelic", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MDAI", + "name": "MDAI", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "40 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 175 mg" + }, + { + "name": "Strong", + "value": "175 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Aminoindane" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "somewhat habit-forming with a low potential for abuse", + "crossTolerances": [ + "entactogens" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MDEA", + "name": "MDEA", + "aliases": [ + "Eve", + "MDE" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "70 - 120 mg" + }, + { + "name": "Common", + "value": "120 - 180 mg" + }, + { + "name": "Strong", + "value": "180 - 225 mg" + }, + { + "name": "Heavy", + "value": "225 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "12 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "MDxx", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "1-1.5 months", + "zero": "2-3 months" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "serotonin|serotonergic", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MDMA", + "name": "MDMA", + "aliases": [ + "Beans", + "E", + "Ecstasy", + "Emma", + "MD", + "Mandy", + "Molly", + "Rolls", + "X", + "XTC" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "15 - 55 mg" + }, + { + "name": "Common", + "value": "55 - 125 mg" + }, + { + "name": "Strong", + "value": "125 - 180 mg" + }, + { + "name": "Heavy", + "value": "180 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "12 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "MDxx", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "1 month", + "zero": "2.5 months" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopaminergic", + "serotonergic", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MDPV", + "name": "MDPV", + "aliases": [ + "Bath Salts", + "NRG-1" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 14 mg" + }, + { + "name": "Strong", + "value": "14 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "Offset", + "value": "0.5 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "MDxx", + "Pyrrolidinophenone", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/MET", + "name": "MET", + "aliases": [ + "Methylethyltryptamine" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 75 minutes" + }, + { + "name": "Onset", + "value": "30 - 60 seconds" + }, + { + "name": "Peak", + "value": "10 - 20 minutes" + }, + { + "name": "Offset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "20 - 60 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "60 - 120 mg" + }, + { + "name": "Common", + "value": "120 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 1.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2.5 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": null, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/MPT", + "name": "MPT", + "aliases": [ + "Methylpropyltryptamine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "??? -\u00a0??? mg", + "note": "\"???\" is not a number." + } + ], + "duration": [ + { + "name": "Total", + "value": "??? -\u00a0???" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MXiPr", + "name": "MXiPr", + "aliases": [ + "MXiP", + "MXiPR" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Mandragora", + "name": "Mandragora", + "aliases": [ + "Mandrake" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Mandragora_officinarum_(botany)", + "name": "Mandragora officinarum (botany)", + "aliases": [ + "Mandrake" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Melatonin", + "name": "Melatonin", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + } + ], + "bioavailability": "15% - 15%" + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Oneirogen" + ] + }, + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "7 days", + "zero": "14 days" + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Memantine", + "name": "Memantine", + "aliases": [ + "Ebixa", + "Memaxa", + "Namenda", + "Namenda XR", + "Namzaric (with donepezil", + "both extended-release)" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "30 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 110 mg" + }, + { + "name": "Strong", + "value": "110 - 170 mg" + }, + { + "name": "Heavy", + "value": "170 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "~ 24 - 72 hours" + }, + { + "name": "Onset", + "value": "2 - 3 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "3 - 12 hours" + }, + { + "name": "Offset", + "value": "5 - 24 hours" + }, + { + "name": "After effects", + "value": "24 - 48 hours" + } + ], + "bioavailability": "41 - 63%" + } + ], + "data": { + "class": { + "chemical": [ + "Adamantanes" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": null, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "unknown", + "crossTolerances": [ + "dissociatives" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Mephedrone", + "name": "Mephedrone", + "aliases": [ + "4-MMC", + "Drone", + "M-CAT", + "Meow Meow" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 45 mg" + }, + { + "name": "Common", + "value": "45 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 125 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Mescaline", + "name": "Mescaline", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 800 mg" + }, + { + "name": "Heavy", + "value": "800 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "45 - 90 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 36 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methadone", + "name": "Methadone", + "aliases": [ + "Dolophine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 90 minutes" + }, + { + "name": "Peak", + "value": "6 - 8 hours" + }, + { + "name": "After effects", + "value": "1 - 24 hours" + } + ], + "bioavailability": "40-99%" + } + ], + "data": { + "class": { + "chemical": [ + "Diphenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methallylescaline", + "name": "Methallylescaline", + "aliases": [ + "MAL" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "4 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methamphetamine", + "name": "Methamphetamine", + "aliases": [ + "Crank", + "Glass", + "Ice", + "Meth", + "Shard", + "Speed", + "Tina" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours", + "note": "Up to 12h for irregular users." + }, + { + "name": "Onset", + "value": "7 - 10 seconds" + }, + { + "name": "Come up", + "value": "5 - 10 seconds" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 24 hours" + } + ], + "bioavailability": ">90%" + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 - 150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 12 hours", + "note": "Up to 24h for irregular users." + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "2.6 - 3.6 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 4 hours" + }, + { + "name": "After effects", + "value": "12 - 24 hours" + } + ], + "bioavailability": "~70%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7", + "note": "Up to 12h for irregular users." + }, + { + "name": "Onset", + "value": "3 - 5" + }, + { + "name": "Come up", + "value": "3 - 5" + }, + { + "name": "Peak", + "value": "1.5 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ], + "bioavailability": ">90%" + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours", + "note": "Up to 18h for irregular users." + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "-" + }, + { + "name": "After effects", + "value": "-" + } + ], + "bioavailability": "~99%" + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 - 80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours", + "note": "Up to 18h for irregular users." + }, + { + "name": "Onset", + "value": "15 - 30 seconds" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "-" + }, + { + "name": "After effects", + "value": "-" + } + ], + "bioavailability": "~100%" + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "rapidly develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulants" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methaqualone", + "name": "Methaqualone", + "aliases": [ + "Ludes", + "Mandrax", + "Quaaludes", + "Sopor" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 - 150 mg" + }, + { + "name": "Light", + "value": "150 - 300 mg" + }, + { + "name": "Common", + "value": "300 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 600 mg" + }, + { + "name": "Heavy", + "value": "600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 minutes" + }, + { + "name": "Come up", + "value": "30 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "6 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Quinazolinone" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of repeated administration", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "doses of over 300mg can be dangerous for first time users", + "safe at appropriate dosages" + ], + "addictionPotential": "extremely addictive", + "crossTolerances": [ + "GABA|gabaergic", + "depressants" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methiopropamine", + "name": "Methiopropamine", + "aliases": [ + "MPA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 120 minutes" + }, + { + "name": "After effects", + "value": "6 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Thiophene" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methoxetamine", + "name": "Methoxetamine", + "aliases": [ + "MXE", + "Mexxy" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 45 mg" + }, + { + "name": "Strong", + "value": "45 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "Come up", + "value": "30 - 75 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methoxphenidine", + "name": "Methoxphenidine", + "aliases": [ + "2-MXP", + "MXP", + "Methoxyphenidine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "50 - 75 mg" + }, + { + "name": "Common", + "value": "75 - 120 mg" + }, + { + "name": "Strong", + "value": "120 - 150 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Diarylethylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methylnaphthidate", + "name": "Methylnaphthidate", + "aliases": [ + "HDMP-28" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "1 - 10 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "< 4 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 14 mg" + }, + { + "name": "Strong", + "value": "14 - 28 mg" + }, + { + "name": "Heavy", + "value": "28 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "90 - 180 minutes" + }, + { + "name": "Onset", + "value": "3 - 6 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methylone", + "name": "Methylone", + "aliases": [ + "M1", + "MDMC", + "bk-MDMA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 mg" + }, + { + "name": "Light", + "value": "75 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 225 mg" + }, + { + "name": "Strong", + "value": "225 - 325 mg" + }, + { + "name": "Heavy", + "value": "325 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 90 minutes" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "1 - 3 weeks", + "zero": "3 - 6 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Methylphenidate", + "name": "Methylphenidate", + "aliases": [ + "Concerta", + "Equasym XL", + "Methylin", + "Ritalin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ], + "bioavailability": "11-52%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "Come up", + "value": "15 - 40 minutes" + }, + { + "name": "Peak", + "value": "30 - 45 minutes" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Metizolam", + "name": "Metizolam", + "aliases": [ + "Desmethyletizolam" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 1 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "10 - 30 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Thienodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of repeated administration", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "large therapeutic index and margin of safety" + ], + "addictionPotential": "extremely addictive", + "crossTolerances": [ + "thienzodiazepines", + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Mexedrone", + "name": "Mexedrone", + "aliases": [ + "4-MMC-MeO" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 350 mg" + }, + { + "name": "Heavy", + "value": "350 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MiPLA", + "name": "MiPLA", + "aliases": [ + "Lamide" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "100 - 150 \u00b5g" + }, + { + "name": "Common", + "value": "150 - 200 \u00b5g" + }, + { + "name": "Strong", + "value": "200 - 250 \u00b5g" + }, + { + "name": "Heavy", + "value": "300 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "low potential for abuse and dependence", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/MiPT", + "name": "MiPT", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 75 mg" + }, + { + "name": "Heavy", + "value": "- mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Mirtazapine", + "name": "Mirtazapine", + "aliases": [ + "Avanza", + "Axit", + "Mirtaz", + "Mirtazon", + "Remeron", + "Zispin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3.5 mg" + }, + { + "name": "Light", + "value": "70 - 130 mg" + }, + { + "name": "Common", + "value": "130 - 190 mg" + }, + { + "name": "Strong", + "value": "190 - 250 mg" + }, + { + "name": "Heavy", + "value": "250 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "14 - 24 hours" + }, + { + "name": "Onset", + "value": "15 - 30 min" + }, + { + "name": "Peak", + "value": "90 - 180 min" + }, + { + "name": "Offset", + "value": "2 - 6 hours" + }, + { + "name": "After effects", + "value": "up to 24 hours" + } + ], + "bioavailability": "50%" + } + ], + "data": { + "class": { + "chemical": [ + "Piperazinoazepine" + ], + "psychoactive": [ + "Deliriant", + "Antidepressant", + "Depressant" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Modafinil", + "name": "Modafinil", + "aliases": [ + "Alertec", + "Modalert", + "Modavigil", + "Modiodal", + "Provigil" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "3.5 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzhydryl" + ], + "psychoactive": [ + "Eugeroic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "The median lethal dose at which 50% of participants die (LD50) from modafinil for human beings has never been reached" + ], + "addictionPotential": "not addictive with a low potential for abuse", + "crossTolerances": [ + "benzhydryl", + "nootropic|nootropics" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Morphine", + "name": "Morphine", + "aliases": [ + "MSContin", + "Oramorph", + "Sevredol", + "Zomorph" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Myristicin", + "name": "Myristicin", + "aliases": [ + "Nutmeg" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 800 mg" + }, + { + "name": "Heavy", + "value": "800 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 72 hours" + }, + { + "name": "Onset", + "value": "3 - 8 hours" + }, + { + "name": "Come up", + "value": "1 - 4 hours" + }, + { + "name": "Peak", + "value": "9 - 12 hours" + }, + { + "name": "Offset", + "value": "12 - 48 hours" + }, + { + "name": "After effects", + "value": "24 - 72 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Phenylpropenes" + ], + "psychoactive": [ + "Deliriant" + ] + }, + "tolerance": null, + "toxicity": [ + "is neurotoxic", + "can be fatal in extremely high doses" + ], + "addictionPotential": "is not known to be addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/N-Acetylcysteine", + "name": "N-Acetylcysteine", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100 mg" + }, + { + "name": "Light", + "value": "400 - 600 mg" + }, + { + "name": "Common", + "value": "600 - 1000 mg" + }, + { + "name": "Strong", + "value": "1000 - 1500 mg" + }, + { + "name": "Heavy", + "value": "1500 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + } + ], + "bioavailability": "4%" + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amino_acid", + "Cysteine" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "develops quickly with repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/N-Ethylhexedrone", + "name": "N-Ethylhexedrone", + "aliases": [ + "Ethyl-Hexedrone", + "Hex-en", + "Hexen", + "NEH" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 10 minutes" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 8 minutes" + }, + { + "name": "Peak", + "value": "30 - 90 minutes" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "norepinephrine|noradrenergic", + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/NEP", + "name": "NEP", + "aliases": [ + "Ethyl-Pentedrone", + "N-Ethylpentedrone" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 3 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/NM-2-AI", + "name": "NM-2-AI", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Aminoindane" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Naloxone", + "name": "Naloxone", + "aliases": [ + "Evzio", + "Narcan" + ], + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Common", + "value": "1 - 4 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0 - 10 minutes" + } + ] + }, + { + "name": "Intramuscular", + "dosage": [ + { + "name": "Common", + "value": "0.4 - 2 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0.25 - 2 minutes" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Common", + "value": "0.4 - 2 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0.25 - 2 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": "not habit-forming", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Nicotine", + "name": "Nicotine", + "aliases": [], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "0.2 mg" + }, + { + "name": "Light", + "value": "0.3 - 0.8 mg" + }, + { + "name": "Common", + "value": "0.8 - 1.5 mg" + }, + { + "name": "Strong", + "value": "1.5 - 3.5 mg" + }, + { + "name": "Heavy", + "value": "3.5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 20 seconds" + }, + { + "name": "Come up", + "value": "5 - 10 seconds" + }, + { + "name": "Peak", + "value": "2 - 5 minutes" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Buccal", + "dosage": [ + { + "name": "Threshold", + "value": "" + }, + { + "name": "Light", + "value": "- mg" + }, + { + "name": "Common", + "value": "- mg" + }, + { + "name": "Strong", + "value": "- mg" + }, + { + "name": "Heavy", + "value": "mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "-" + }, + { + "name": "Onset", + "value": "-" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "-" + }, + { + "name": "Offset", + "value": "-" + }, + { + "name": "After effects", + "value": "-" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Pyridine", + "Substituted_pyrrolidines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "rapidly develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Nifoxipam", + "name": "Nifoxipam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1 mg" + }, + { + "name": "Strong", + "value": "1 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 75 hours" + }, + { + "name": "Onset", + "value": "45 - 120 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/O-Desmethyltramadol", + "name": "O-Desmethyltramadol", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "moderate potential toxicity relative to its dose due to its potency", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/O-PCE", + "name": "O-PCE", + "aliases": [ + "Eticyclidone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "3 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Omberacetam", + "name": "Omberacetam", + "aliases": [ + "GVS-111", + "Noopept", + "\u041d\u043e\u043e\u043f\u0435\u043f\u0442" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 hours" + }, + { + "name": "Offset", + "value": "3 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "1 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "0 - 5 minutes" + }, + { + "name": "Peak", + "value": "2 hours" + }, + { + "name": "Offset", + "value": "3 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Peptide" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "develops over several weeks of prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "crossTolerances": [ + "racetam", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Oxiracetam", + "name": "Oxiracetam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "250 mg" + }, + { + "name": "Light", + "value": "500 - 1200 mg" + }, + { + "name": "Common", + "value": "1200 - 1800 mg" + }, + { + "name": "Strong", + "value": "1800 - 2400 mg" + }, + { + "name": "Heavy", + "value": "2400 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Stimulants", + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "safe even when high doses are consumed for a long period of time", + "exact toxic dosage is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "crossTolerances": [ + "racetam", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Oxycodone", + "name": "Oxycodone", + "aliases": [ + "Codilek", + "Endone", + "Oxecta", + "Oxy", + "OxyContin", + "OxyIR", + "Oxydor", + "Oxygesic", + "Oxynor", + "Redocam", + "Roxicodone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2.5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2.5 - 7.5 mg" + }, + { + "name": "Common", + "value": "7.5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Oxymorphone", + "name": "Oxymorphone", + "aliases": [ + "Opana" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2.5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/PARGY-LAD", + "name": "PARGY-LAD", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 \u00b5g" + }, + { + "name": "Light", + "value": "125 - 275 \u00b5g" + }, + { + "name": "Common", + "value": "275 - 500 \u00b5g" + }, + { + "name": "Strong", + "value": "500 - 700 \u00b5g" + }, + { + "name": "Heavy", + "value": "700 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/PCE", + "name": "PCE", + "aliases": [ + "Eticyclidine" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "40 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "3 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", + "crossTolerances": [ + "dissociative" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/PCP", + "name": "PCP", + "aliases": [ + "Angel Dust", + "Sernyl", + "Sherman", + "Wet" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "40 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "3 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", + "crossTolerances": [ + "dissociative|dissociatives" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/PMA", + "name": "PMA", + "aliases": [ + "4-MA", + "Death" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": null, + "note": "Higher dosages can result in serious hyperthermia and eventually death." + } + ], + "duration": [ + { + "name": "Total", + "value": "short" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "tolerance": null, + "toxicity": [ + "can be considered extremely toxic when compared to other substances such as Methamphetamine or MDMA", + "Ingestion of PMA has been associated with severe tachycardia (abnormally high heart rate), seizures, hyperthermia, and death" + ], + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/PMMA", + "name": "PMMA", + "aliases": [ + "4-MMA", + "PMA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "100 - 120 mg" + }, + { + "name": "Strong", + "value": null, + "note": "Higher dosages can result in serious hyperthermia and eventually death." + } + ], + "duration": [ + { + "name": "Total", + "value": "short" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "tolerance": null, + "toxicity": [ + "can be considered extremely toxic when compared to other substances such as Methamphetamine or MDMA", + "Ingestion of PMMA has been associated with severe tachycardia (abnormally high heart rate), seizures, hyperthermia, and death" + ], + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/PRO-LAD", + "name": "PRO-LAD", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 \u00b5g" + }, + { + "name": "Light", + "value": "50 - 100 \u00b5g" + }, + { + "name": "Common", + "value": "100 - 200 \u00b5g" + }, + { + "name": "Strong", + "value": "200 - 350 \u00b5g" + }, + { + "name": "Heavy", + "value": "350 \u00b5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Peganum_harmala", + "name": "Peganum harmala", + "aliases": [ + "Esfand", + "Espand", + "Syrian rue" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Pentedrone", + "name": "Pentedrone", + "aliases": [ + "Drone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 10 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Pentobarbital", + "name": "Pentobarbital", + "aliases": [ + "Nembutal", + "pentobarbitone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 36 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Barbiturates" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": null, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Pethidine", + "name": "Pethidine", + "aliases": [ + "Demerol", + "Dolantin", + "Dolcontral", + "Meperidine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 - 50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 400 mg" + }, + { + "name": "Heavy", + "value": "400 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "2 - 10 hours" + } + ], + "bioavailability": "50-60%" + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_piperidines" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "high toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Phenibut", + "name": "Phenibut", + "aliases": [ + "Fenibut", + "PhGABA", + "Phenybut" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 g" + }, + { + "name": "Light", + "value": "0.5 - 1 g" + }, + { + "name": "Common", + "value": "1 - 2 g" + }, + { + "name": "Strong", + "value": "2 - 3.5 g" + }, + { + "name": "Heavy", + "value": "3.5 g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 16 hours" + }, + { + "name": "Onset", + "value": "1.5 - 3 hours" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + }, + { + "name": "Offset", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Gabapentinoids" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "crossTolerances": [ + "GABA" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Phenobarbital", + "name": "Phenobarbital", + "aliases": [ + "Luminal", + "phenobarb", + "phenobarbitone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "1 - 48 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Barbiturates" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": null, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Phenylpiracetam", + "name": "Phenylpiracetam", + "aliases": [ + "Carphedon", + "Phenotropil" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 400 mg" + }, + { + "name": "Heavy", + "value": "400 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours (some users have reported effects lasting an entire day)" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 hour" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Stimulants", + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "safe even when high doses are consumed for a long period of time", + "exact toxic dosage is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "crossTolerances": [ + "racetam", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Piper_nigrum_(botany)", + "name": "Piper nigrum (botany)", + "aliases": [ + "Black pepper", + "Green pepper", + "White pepper", + "peppercorn" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Piracetam", + "name": "Piracetam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 - 0.5g" + }, + { + "name": "Light", + "value": "0.5 - 2g" + }, + { + "name": "Common", + "value": "2 - 3g" + }, + { + "name": "Strong", + "value": "3 - 5g" + }, + { + "name": "Heavy", + "value": "5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "not addictive with a low potential for abuse", + "crossTolerances": [ + "racetam", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Pramiracetam", + "name": "Pramiracetam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100 mg" + }, + { + "name": "Light", + "value": "250 - 500 mg" + }, + { + "name": "Common", + "value": "500 - 800 mg" + }, + { + "name": "Strong", + "value": "800 - 1200 mg" + }, + { + "name": "Heavy", + "value": "1200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "not addictive with a low potential for abuse", + "crossTolerances": [ + "racetam", + "nootropic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Prochlorperazine", + "name": "Prochlorperazine", + "aliases": [ + "Buccastem", + "Compazine", + "Phenotil", + "Stemetil", + "Stemzine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "2.5 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Phenothiazine" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Prolintane", + "name": "Prolintane", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 45 mg" + }, + { + "name": "Strong", + "value": "45 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_pyrrolidines", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Propylhexedrine", + "name": "Propylhexedrine", + "aliases": [ + "Benzedrex" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "31.25 - 62.5 mg" + }, + { + "name": "Common", + "value": "62.5 - 125 mg" + }, + { + "name": "Strong", + "value": "125 - 187.5 mg" + }, + { + "name": "Heavy", + "value": "187.5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 10 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Cycloalkylamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "rapidly develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": [ + "dopamine", + "stimulant" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Proscaline", + "name": "Proscaline", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "3 - 5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "no negative health effects attributed to trying this drug" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Psilocin", + "name": "Psilocin", + "aliases": [ + "4-HO-DMT", + "4-OH-DMT", + "Psilocine", + "Psilocyn", + "Psilotsin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Psilocybe_cubensis", + "name": "Psilocybe cubensis", + "aliases": [ + "Shrooms", + "magic mushroom" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Pyrazolam", + "name": "Pyrazolam", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "10 - 15 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Quetiapine", + "name": "Quetiapine", + "aliases": [ + "Seroquel" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 6 hours" + }, + { + "name": "Offset", + "value": "6 - 7 hours" + }, + { + "name": "After effects", + "value": "24 - 48 hours" + } + ], + "bioavailability": "100% - 100%" + } + ], + "data": { + "class": { + "chemical": [ + "Dibenzothiazepine" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "tolerance": { + "full": "within a week of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Risperidone", + "name": "Risperidone", + "aliases": [ + "Risperdal" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 20 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 8 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "12 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzisoxazole" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/SAM-e", + "name": "SAM-e", + "aliases": [ + "Methylguanidoacetic acid", + "S-Adenosyl methionine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "200 mg" + }, + { + "name": "Light", + "value": "400 - 800 mg" + }, + { + "name": "Common", + "value": "800 - 1200 mg" + }, + { + "name": "Strong", + "value": "1200 - 1600 mg" + }, + { + "name": "Heavy", + "value": "1600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "100 - 180 minutes" + } + ], + "bioavailability": "2-10%" + } + ], + "data": { + "class": { + "chemical": [ + "Nitrogenous_organic_acid" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": null, + "toxicity": null, + "addictionPotential": "not habit-forming with a low potential for abuse", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/STS-135", + "name": "STS-135", + "aliases": [], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Common", + "value": "1.5 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "10 - 45 seconds" + }, + { + "name": "Come up", + "value": "10 - 45 minutes" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "15 - 45 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Adamantanes", + "Indolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "cannabinoids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Salvia_divinorum", + "name": "Salvia divinorum", + "aliases": [ + "Sage of the Diviners", + "Sally", + "Salvia", + "seer's sage", + "ska mar\u00eda pastora", + "yerba de la pastora" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Salvinorin_A", + "name": "Salvinorin A", + "aliases": [ + "Diviner's Sage", + "Sally", + "Salvia", + "Salvia divinorum", + "Seer's Sage", + "Ska Mar\u00eda Pastora" + ], + "roas": [ + { + "name": "Smoked", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "15 - 90 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "After effects", + "value": "15 - 60 minutes" + } + ] + }, + { + "name": "Sublingual", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "30 - 90 minutes" + }, + { + "name": "Onset", + "value": "10 - 20 minutes" + }, + { + "name": "After effects", + "value": "30 - 120 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Terpenoid", + "Salvinorin" + ], + "psychoactive": [ + "Hallucinogens" + ] + }, + "tolerance": null, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "hallucinogen" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Secobarbital", + "name": "Secobarbital", + "aliases": [ + "Seconal", + "secobarbitone" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Barbiturates" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": null, + "toxicity": [ + "moderate toxicity" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Sufentanil", + "name": "Sufentanil", + "aliases": [ + "Chronogesic,", + "Sufenta", + "sufentanyl" + ], + "roas": [ + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "0.1 \u03bcg" + }, + { + "name": "Light", + "value": "1 - 5 \u03bcg" + }, + { + "name": "Common", + "value": "5 - 10 \u03bcg" + }, + { + "name": "Strong", + "value": "10 - 25 \u03bcg" + }, + { + "name": "Heavy", + "value": "25 \u03bcg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 2 minutes" + }, + { + "name": "Peak", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "1 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Anilidopiperidine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": null, + "zero": null + }, + "toxicity": [ + "potentially fatal at heavy dosages", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "unintentionally spilling a very small amount of sufentanil on one's skin could result in a fatal overdose." + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/THJ-018", + "name": "THJ-018", + "aliases": [], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 1 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "60 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Naphthoylindazole" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "cannabinoids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/THJ-2201", + "name": "THJ-2201", + "aliases": [], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 45 minutes" + }, + { + "name": "Offset", + "value": "0 - 0 minutes (Abrupt)" + }, + { + "name": "After effects", + "value": "60 - 90 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Naphthoylindazole" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "cannabinoids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/TMA-2", + "name": "TMA-2", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 120 minutes" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/TMA-6", + "name": "TMA-6", + "aliases": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 16 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "5 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 18 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Tabernanthe_iboga_(botany)", + "name": "Tabernanthe iboga (botany)", + "aliases": [ + "Iboga" + ], + "roas": [], + "data": { + "class": null, + "tolerance": null, + "toxicity": null, + "addictionPotential": null, + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Tapentadol", + "name": "Tapentadol", + "aliases": [ + "Nucynta", + "Palexia", + "Yantil", + "Yantil SR" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "12.5 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 75 mg" + }, + { + "name": "Strong", + "value": "75 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "1 - 6 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Temazepam", + "name": "Temazepam", + "aliases": [ + "Normison", + "Restoril" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 90 minutes" + }, + { + "name": "After effects", + "value": "6 - 12 hour" + } + ], + "bioavailability": "96%" + } + ], + "data": { + "class": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7-14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Theacrine", + "name": "Theacrine", + "aliases": [ + "Temorine", + "Temurin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Common", + "value": "25 - 100 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Xanthines", + "Purine_alkaloid" + ], + "psychoactive": [ + "Stimulants", + "Nootropic" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": null, + "addictionPotential": "produces dependence with chronic use and has a low abuse potential", + "crossTolerances": [] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Theanine", + "name": "Theanine", + "aliases": [ + "L-Theanine", + "L-\u03b3-glutamylethylamide and N5-ethyl-L-glutamine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "75 - 175 mg" + }, + { + "name": "Common", + "value": "175 - 300 mg" + }, + { + "name": "Strong", + "value": "300 - 500 mg" + }, + { + "name": "Heavy", + "value": "500 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amino_acid_analogue" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "5 days", + "zero": "10 days" + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Tianeptine", + "name": "Tianeptine", + "aliases": [ + "Coaxil", + "Stablon", + "Tatinol" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "6 - 12 mg" + }, + { + "name": "Common", + "value": "12 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + } + ], + "bioavailability": "99%" + } + ], + "data": { + "class": { + "chemical": [ + "Dibenzothiazepine", + "Tricyclic_antidepressant" + ], + "psychoactive": [ + "Nootropic", + "Opioids" + ] + }, + "tolerance": { + "full": "with prolonged use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "large therapeutic index and margin of safety" + ], + "addictionPotential": "mildly addictive", + "crossTolerances": [ + "trycyclic antidepressants", + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Tramadol", + "name": "Tramadol", + "aliases": [ + "Tadol", + "Tramacur", + "Tramal", + "Tramundin" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + } + ], + "bioavailability": "70 - 90%" + } + ], + "data": { + "class": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Tyrosine", + "name": "Tyrosine", + "aliases": [ + "L-Tyrosine or 4-hydroxyphenylalanine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "300 mg" + }, + { + "name": "Light", + "value": "500 - 1000 mg" + }, + { + "name": "Common", + "value": "1000 - 2000 mg" + }, + { + "name": "Strong", + "value": "2000 - 3000 mg" + }, + { + "name": "Heavy", + "value": "3000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Amino_acid", + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "tolerance": { + "full": "after repeated and frequent usage", + "half": "7 days", + "zero": "14 days" + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "mildly habit forming", + "crossTolerances": [ + "dopamine" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/U-47700", + "name": "U-47700", + "aliases": [], + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "4 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 10 mg" + }, + { + "name": "Heavy", + "value": "10 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "15 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Benzamide" + ], + "psychoactive": [ + "Opioids" + ] + }, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "toxicity": [ + "high toxicity relative to its dose due to its extreme potency", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "crossTolerances": [ + "opioids" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/Zolpidem", + "name": "Zolpidem", + "aliases": [ + "Ambien", + "Edluar", + "Intermezzo", + "Zolpimist" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "60 - 120 minutes" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "5 - 15 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Imidazopyridine" + ], + "psychoactive": [ + "Hallucinogens", + "Depressant" + ] + }, + "tolerance": null, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "moderately addictive", + "crossTolerances": null + } + }, + { + "url": "https://psychonautwiki.org/wiki/Zopiclone", + "name": "Zopiclone", + "aliases": [ + "Imovane", + "Zimovane" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "3.5 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 7.5 mg" + }, + { + "name": "Strong", + "value": "7.5 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3.5 - 9 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + } + ], + "bioavailability": "52 - 59%" + } + ], + "data": { + "class": { + "chemical": [ + "Cyclopyrrolone" + ], + "psychoactive": [ + "Hallucinogens", + "Depressant" + ] + }, + "tolerance": { + "full": "within a couple of weeks of daily use", + "half": null, + "zero": "7 - 14 days" + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like benzodiazepines, alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "crossTolerances": [ + "benzodiazepines" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/%CE%91MT", + "name": "\u0391MT", + "aliases": [ + "AMT", + "Indopan", + "\u03b1MT" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 - 80 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "13 - 15 hours" + }, + { + "name": "Onset", + "value": "60 - 180 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "1 - 5 hours" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics", + "Entactogens" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "14 days", + "zero": "1 month" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "moderately habit-forming", + "crossTolerances": [ + "psychedelics" + ] + } + }, + { + "url": "https://psychonautwiki.org/wiki/%CE%92k-2C-B", + "name": "\u0392k-2C-B", + "aliases": [ + "beta-keto 2C-B", + "bk-2C-B", + "\u03b2k-2C-B" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "60 - 80 mg" + }, + { + "name": "Common", + "value": "80 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 70 minutes" + } + ] + } + ], + "data": { + "class": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "crossTolerances": [ + "psychedelic" + ] + } + } +] \ No newline at end of file diff --git a/ts_pn_data/getData.py b/ts_pn_data/getData.py new file mode 100644 index 0000000..b74f1fb --- /dev/null +++ b/ts_pn_data/getData.py @@ -0,0 +1,558 @@ +#!/usr/bin/env python3 + +# downloads and exports data on all substances from psychonautwiki and tripsit factsheets, combining to form master list with standardized format +# prioritizes psychonautwiki ROA info (dose/duration) over tripsit factsheets +# pip3 install beautifulsoup4 requests python-graphql-client + +import requests +from bs4 import BeautifulSoup +from time import time, sleep +from python_graphql_client import GraphqlClient +import json +import os +import re +import traceback + +headers = { + "Access-Control-Allow-Origin": "*", + "Access-Control-Allow-Methods": "GET", + "Access-Control-Allow-Headers": "Content-Type", + "Access-Control-Max-Age": "3600", + "User-Agent": "Mozilla/5.0 (X11; Ubuntu; Linux x86_64; rv:52.0) Gecko/20100101 Firefox/52.0", +} + +ts_api_url = "https://tripbot.tripsit.me/api/tripsit/getAllDrugs" +ps_api_url = "https://api.psychonautwiki.org" +ps_client = GraphqlClient(endpoint=ps_api_url, headers=headers) + + +def substance_name_match(name, substance): + """check if name matches any value in keys we care about""" + lower_name = name.lower() + return any( + [ + lower_name == substance[key].lower() + for key in ["name", "pretty_name"] + if key in substance + ] + + [lower_name == alias.lower() for alias in substance.get("aliases", [])] + ) + + +def find_substance_in_data(data, name): + return next((s for s in data if substance_name_match(name, s)), None) + + +roa_name_aliases = { + "iv": ["intravenous"], + "intravenous": ["iv"], + "im": ["intramuscular"], + "intramuscular": ["im"], + "insufflated": ["snorted"], + "snorted": ["insufflated"], + "vaporized": ["vapourized"], + "vapourized": ["vaporized"], +} + + +def roa_matches_name(roa, name): + aliases = roa_name_aliases.get(name.lower(), []) + return roa["name"].lower() == name.lower() or roa["name"].lower() in aliases + + +# get tripsit data + + +ts_dose_order = ["Threshold", "Light", "Common", "Strong", "Heavy"] +ts_combo_ignore = ["benzos"] # duplicate +# prettify names in interaction list +ts_combo_transformations = { + "lsd": "LSD", + "mushrooms": "Mushrooms", + "dmt": "DMT", + "mescaline": "Mescaline", + "dox": "DOx", + "nbomes": "NBOMes", + "2c-x": "2C-x", + "2c-t-x": "2C-T-x", + "amt": "aMT", + "5-meo-xxt": "5-MeO-xxT", + "cannabis": "Cannabis", + "ketamine": "Ketamine", + "mxe": "MXE", + "dxm": "DXM", + "pcp": "PCP", + "nitrous": "Nitrous", + "amphetamines": "Amphetamines", + "mdma": "MDMA", + "cocaine": "Cocaine", + "caffeine": "Caffeine", + "alcohol": "Alcohol", + "ghb/gbl": "GHB/GBL", + "opioids": "Opioids", + "tramadol": "Tramadol", + "benzodiazepines": "Benzodiazepines", + "maois": "MAOIs", + "ssris": "SSRIs", +} + +ts_response = requests.get(ts_api_url) +ts_data = ts_response.json()["data"][0] + +ts_substances_data = list(ts_data.values()) + + +# TS has durations split over a few keys, so this finds or creates the duration for the associated ROA +# and adds a new line item +def ts_add_formatted_duration(ts_roas, formatted_duration, duration_name): + units = formatted_duration.get("_unit", "") or "" + if "_unit" in formatted_duration: + formatted_duration.pop("_unit") + + def add_to_roa(roa, value): + if "duration" not in roa: + roa["duration"] = [] + + roa["duration"].append({"name": duration_name, "value": value}) + + for roa_name, value in formatted_duration.items(): + value_string = f"{value} {units}".strip() + + # if value present (i.e. just one value for all ROA doses provided above), apply to all ROAs + if roa_name == "value": + # if TS did not add any doses, do nothing with this value + # we could theoretically apply this to all PW doses with missing durations, but we can't be sure + # if it applies to all ROAs, so just ignore + if not len(ts_roas): + break + + for ts_roa in ts_roas: + add_to_roa(ts_roa, value_string) + + # add to matching ROA or create new ROA if doesn't exist + else: + ts_roa = next( + (ts_roa for ts_roa in ts_roas if roa_matches_name(ts_roa, roa_name)), + None, + ) + # if ROA doesn't exist, make new + if not ts_roa: + ts_roa = {"name": roa_name} + ts_roas.append(ts_roa) + + add_to_roa(ts_roa, value_string) + + +# get psychonautwiki data + + +def pw_clean_common_name(name): + name = re.sub(r'^"', "", name) + name = re.sub(r'"$', "", name) + name = re.sub(r'"?\[\d*\]$', "", name) + name = re.sub(r"\s*More names\.$", "", name) + name = re.sub(r"\.$", "", name) + return name.strip() + + +def pw_should_skip(name, soup): + return ( + name.startswith("Experience:") or len(soup.find_all(text="Common names")) == 0 + ) + + +pw_substance_data = [] + +if os.path.exists("ts_pn_data/_cached_pw_substances.json"): + with open("ts_pn_data/_cached_pw_substances.json") as f: + pw_substance_data = json.load(f) + +if not len(pw_substance_data): + offset = 0 + pw_substance_urls_query = ( + f"{{substances(limit: 250 offset: {offset}) {{name url}}}}" + ) + + pw_substance_urls_data = ps_client.execute(query=pw_substance_urls_query,)["data"][ + "substances" + ] + + offset = 252 + while offset <= 340: + pw_substance_urls_query = ( + f"{{substances(limit: 1 offset: {offset}) {{name url}}}}" + ) + offset += 1 + temp_data = ps_client.execute(query=pw_substance_urls_query,)["data"][ + "substances" + ] + print(temp_data) + if temp_data is None: + continue + pw_substance_urls_data.extend(temp_data) + + for idx, substance in enumerate(pw_substance_urls_data): + try: + url = substance["url"] + substance_req = requests.get(url, headers) + substance_soup = BeautifulSoup(substance_req.content, "html.parser") + + name = substance_soup.find("h1", id="firstHeading").text + if pw_should_skip(name, substance_soup): + print(f"Skipping {name} ({idx + 1} / {len(pw_substance_urls_data)})") + continue + + # get aliases text + common_names_str = substance_soup.find_all(text="Common names") + + cleaned_common_names = ( + set( + map( + pw_clean_common_name, + common_names_str[0] + .parent.find_next_sibling("td") + .text.split(", "), + ) + ) + if len(common_names_str) > 0 + else set() + ) + cleaned_common_names.add(substance["name"]) + # don't include name in list of other common names + common_names = sorted(filter(lambda n: n != name, cleaned_common_names)) + + # scrape ROAs from page + + def get_data_starting_at_row(curr_row): + rows = [] + while curr_row.find("th", {"class": "ROARowHeader"}): + row = {} + row["name"] = ( + curr_row.find("th", {"class": "ROARowHeader"}).find("a").text + ) + + row_values = curr_row.find("td", {"class": "RowValues"}) + + row_value_text = row_values.find_all(text=True, recursive=False) + if len(row_value_text): + row["value"] = "".join(row_value_text).strip() + else: + row["value"] = None + + row_note = row_values.find("span") + if row_note: + row["note"] = re.sub(r"\s*\[\d*\]$", "", row_note.text).strip() + + rows.append(row) + + curr_row = curr_row.find_next("tr") + return rows, curr_row + + roas = [] + + dose_charts = substance_soup.find_all("tr", {"class": "dosechart"}) + for dose_chart in dose_charts: + table = dose_chart.parent.parent + roa_name = table.find("tr").find("a").text + if not roa_name: + continue + + roa = { + "name": roa_name, + "dosage": [], + "duration": [], + } + + # dosage + + curr_row = dose_chart.find_next("tr") + roa["dosage"], curr_row = get_data_starting_at_row(curr_row) + + # extract bioavailability + if len(roa["dosage"]) and roa["dosage"][0]["name"] == "Bioavailability": + bioavailability = roa["dosage"].pop(0) + roa["bioavailability"] = bioavailability["value"] + + # duration + + if curr_row.find("th", {"class": "ROASubHeader"}): + curr_row = curr_row.find_next("tr") + roa["duration"], _ = get_data_starting_at_row(curr_row) + + if not len(roa["dosage"]): + roa["dosage"] = None + if not len(roa["duration"]): + roa["duration"] = None + + roas.append(roa) + + # query PS API for more data on substance + + query = ( + """ + { + substances(query: "%s") { + name + class { + chemical + psychoactive + } + tolerance { + full + half + zero + } + toxicity + addictionPotential + crossTolerances + } + } + """ + % substance["name"] + ) + + data = ps_client.execute(query=query)["data"]["substances"] + if len(data) == 0: + continue + elif len(data) > 1: + # should never happen? + print(f"{name} has more than one dataset... investigate why") + + data = data[0] + if "name" in data: + data.pop("name") + + pw_substance_data.append( + { + "url": url, + "name": name, + "aliases": common_names, + "roas": roas, + "data": data, + } + ) + print( + f"Done with {name} [{len(roas)} ROA(s)] ({idx + 1} / {len(pw_substance_urls_data)})" + ) + + except KeyboardInterrupt: + print("\nScrape canceled") + exit(0) + except: + print(f"{name} failed:") + print(traceback.format_exc()) + exit(1) + + with open(f"ts_pn_data/_cached_pw_substances.json", "w") as f: + f.write(json.dumps(pw_substance_data, indent=2, ensure_ascii=False)) + +# combine tripsit and psychonautwiki data + + +all_substance_names = sorted( + set( + list(map(lambda s: s.get("name", "").lower(), pw_substance_data)) + + list(map(lambda s: s.get("name", "").lower(), ts_substances_data)) + ) +) +substance_data = [] +x = 0 + +for name in all_substance_names: + # find PW substance + pw_substance = find_substance_in_data(pw_substance_data, name) + # remove to get rid of duplicates in final output + if pw_substance: + pw_substance_data.remove(pw_substance) + else: + pw_substance = {} + + # find TS substance + ts_substance = find_substance_in_data(ts_substances_data, name) + # remove to get rid of duplicates in final output + if ts_substance: + ts_substances_data.remove(ts_substance) + else: + ts_substance = {} + + # if no substance found in either dataset, skip + if not pw_substance and not ts_substance: + continue + + ts_properties = ts_substance.get("properties", {}) + + # url will always exist for psychonautwiki substance, so tripsit substance must exist if url is None + url = pw_substance.get("url") or f"https://drugs.tripsit.me/{ts_substance['name']}" + + ts_links = ts_substance.get("links", {}) + experiences_url = ts_links.get("experiences") + + # pick display name from available substances found from both datasets + names = list( + filter( + lambda n: n is not None and len(n) > 0, + [pw_substance.get("name"), ts_substance.get("pretty_name")], + ) + ) + # people use shorter names + name = min(names, key=len) + + # lowercase list of all names, excluding chosen name above + aliases = set( + map( + lambda n: n.lower(), + filter( + lambda n: n is not None and len(n) > 0, + [pw_substance.get("name"), ts_substance.get("pretty_name")] + + pw_substance.get("aliases", []) + + ts_substance.get("aliases", []), + ), + ) + ) + if name.lower() in aliases: + aliases.remove(name.lower()) + aliases = sorted(aliases) + + summary = ts_properties.get("summary", "").strip() + if not len(summary): + summary = None + + test_kits = ts_properties.get("test-kits", "").strip() + if not len(test_kits): + test_kits = None + + ts_bioavailability_str = ts_properties.get("bioavailability", "").strip() + ts_bioavailability = {} + if len(ts_bioavailability_str): + matches = re.findall( + r"([a-zA-Z\/]+)[.:\s]+([0-9\.%\s\+/\-]+)", ts_bioavailability_str + ) + if len(matches): + for roa_name, value in matches: + ts_bioavailability[roa_name.lower()] = value.strip(". \t") + + pw_data = pw_substance.get("data", {}) + + classes = pw_data.get("class") + toxicity = pw_data.get("toxicity") + addiction_potential = pw_data.get("addictionPotential") + tolerance = pw_data.get("tolerance") + cross_tolerances = pw_data.get("crossTolerances") + + roas = [] + + # get PW ROAs + pw_roas = pw_substance.get("roas", []) + + # process TS ROAs + ts_roas = [] + + # TS ROA dosage + ts_formatted_dose = ts_substance.get("formatted_dose") + if ts_formatted_dose: + for roa_name, dose_data in ts_formatted_dose.items(): + dose_levels = [] + for dose_level in ts_dose_order: + value_string = dose_data.get(dose_level) + if value_string is None: + continue + + dose_levels.append( + {"name": dose_level, "value": value_string,} + ) + + if len(dose_levels): + ts_roas.append({"name": roa_name, "dosage": dose_levels}) + + # TS ROA durations + ts_formatted_onset = ts_substance.get("formatted_onset") + if ts_formatted_onset: + ts_add_formatted_duration(ts_roas, ts_formatted_onset, "Onset") + + ts_formatted_duration = ts_substance.get("formatted_duration") + if ts_formatted_duration: + ts_add_formatted_duration(ts_roas, ts_formatted_duration, "Duration") + + ts_formatted_aftereffects = ts_substance.get("formatted_aftereffects") + if ts_formatted_aftereffects: + ts_add_formatted_duration(ts_roas, ts_formatted_aftereffects, "After effects") + + # merge PW and TS ROAs + # prioritize PW for ROAs but use TS to fill in gaps + + roas.extend(pw_roas) + for ts_roa in ts_roas: + existing_roa = next( + (roa for roa in roas if roa_matches_name(roa, ts_roa["name"])), None + ) + # if ROA does not exist, add + if not existing_roa: + existing_roa = ts_roa + roas.append(existing_roa) + # we want bioavailability from below, so don't skip + + # if ROA does not already have bioavailability, try to get from TS + if not existing_roa.get("bioavailability"): + name_lower = ts_roa["name"].lower() + name_aliases = roa_name_aliases.get(name_lower, []) + + alias_found = next( + (name_alias in ts_bioavailability for name_alias in name_aliases), None + ) + # TS has bioavailability if name or any name alias is found + if name_lower in ts_bioavailability or alias_found: + existing_roa["bioavailability"] = ts_bioavailability.get( + name_lower + ) or ts_bioavailability.get(alias_found) + + # if existing ROA is missing dosage and TS has dosage, add + if (not existing_roa.get("dosage") or not len(existing_roa["dosage"])) and ( + "dosage" in ts_roa and ts_roa["dosage"] and len(ts_roa["dosage"]) + ): + existing_roa["dosage"] = ts_roa["dosage"] + + # if existing ROA is missing duration and TS has duration, add + if (not existing_roa.get("duration") or not len(existing_roa["duration"])) and ( + "duration" in ts_roa and ts_roa["duration"] and len(ts_roa["duration"]) + ): + existing_roa["duration"] = ts_roa["duration"] + + interactions = None + combos = ts_substance.get("combos") + if combos: + interactions = [] + for key, combo_data in combos.items(): + if key in ts_combo_ignore: + continue + + combo_data["name"] = ts_combo_transformations[key] + interactions.append(combo_data) + interactions = sorted(interactions, key=lambda i: i["name"]) + + substance_data.append( + { + "id": x, + "name": name, + "aliases": list(aliases), + "aliasesStr": ",".join(aliases), + "url": url, + "experiencesUrl": experiences_url, + "summary": summary, + "reagents": test_kits, + "classes": classes, + "toxicity": toxicity, + "addictionPotential": addiction_potential, + "tolerance": tolerance, + "crossTolerances": cross_tolerances, + "roas": roas, + "interactions": interactions, + } + ) + x += 1 + +# output + + +substances_json = json.dumps(substance_data, indent=2, ensure_ascii=False) +with open(f"ts_pn_data/substances_{time()}.json", "w") as f: + f.write(substances_json) diff --git a/ts_pn_data/substances_1632949161.9573479.json b/ts_pn_data/substances_1632949161.9573479.json new file mode 100644 index 0000000..1283f63 --- /dev/null +++ b/ts_pn_data/substances_1632949161.9573479.json @@ -0,0 +1,45372 @@ +[ + { + "id": 0, + "name": "1,4-Butanediol", + "aliases": [ + "1,4-b", + "1,4-bd", + "14bd", + "bd", + "bdo", + "butylene glycol", + "one comma four", + "one four bee", + "or one four b-d-o" + ], + "aliasesStr": "1,4-b,1,4-bd,14bd,bd,bdo,butylene glycol,one comma four,one four bee,or one four b-d-o", + "url": "https://psychonautwiki.org/wiki/1,4-Butanediol", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_14Butanediol.shtml", + "summary": "1,4-BD is a clear liquid with intoxicating effects. It is a pro-drug for GHB, and has similar though reportedly inferior effects. It also carries the potential for more health risks than GHB, such as liver toxicity.", + "reagents": "Marquis: Faint Brown. | Mandelin: Brown.", + "classes": { + "chemical": [ + "Diol", + "Alkanediol" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "tolerance": { + "full": "within several weeks of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mL" + }, + { + "name": "Light", + "value": "0.5 - 1 mL" + }, + { + "name": "Common", + "value": "1 - 2.5 mL" + }, + { + "name": "Strong", + "value": "2.5 - 4 mL" + }, + { + "name": "Heavy", + "value": "4 mL +", + "note": "Warning: Doses above 4 mL can induce heavy sleep and doses above 6 mL can lead to poisoning" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "20 minutes - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 1, + "name": "1B-LSD", + "aliases": [ + "1b" + ], + "aliasesStr": "1b", + "url": "https://psychonautwiki.org/wiki/1B-LSD", + "experiencesUrl": null, + "summary": "1B-LSD (1-butanoyl-lysergic acid diethylamide) is an LSD analogue which appears to be about as potent as 1P-LSD (slightly more potent than LSD) and has a slightly shorter duration than that of LSD, again thought to be about the same as 1P-LSD. Released in late 2018, and marketed agressively as a replacement for 1P-LSD. 1B-LSD does not yet have a clearly established safety profile,", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "extremely low toxicity relative to dose" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 µg" + }, + { + "name": "Light", + "value": "25 - 75 µg" + }, + { + "name": "Common", + "value": "75 - 150 µg" + }, + { + "name": "Strong", + "value": "150 - 300 µg" + }, + { + "name": "Heavy", + "value": "300 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 2, + "name": "1CP-LSD", + "aliases": [ + "1cp", + "1cplsd", + "curie" + ], + "aliasesStr": "1cp,1cplsd,curie", + "url": "https://drugs.tripsit.me/1cp-lsd", + "experiencesUrl": null, + "summary": "1cP-LSD (1-cyclopropionyl-lysergic acid diethylamide) is a novel lysergamide with little to no history of use. It is said to be a less pushy and shorter lasting version of LSD. Described as having a more gradual onset than 1P-LSD, with a less visual more meditative headspace when compared with LSD.*NOTE: This is a very new research chemical - take all info with a grain of salt.*", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-50ug" + }, + { + "name": "Common", + "value": "50-100ug" + }, + { + "name": "Strong", + "value": "100-200ug" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "8-10 hours" + }, + { + "name": "After effects", + "value": "6-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 3, + "name": "1P-ETH-LAD", + "aliases": [ + "1pethlad" + ], + "aliasesStr": "1pethlad", + "url": "https://psychonautwiki.org/wiki/1P-ETH-LAD", + "experiencesUrl": null, + "summary": "A new psychedelic lysergamide which is suspected to be a prodrug of ETH-LAD, which could explain why the doses are very similar. Or it could be active on its own. Scientific studies would need to be written to understand, yet there are none.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 µg" + }, + { + "name": "Light", + "value": "30 - 60 µg" + }, + { + "name": "Common", + "value": "60 - 100 µg" + }, + { + "name": "Strong", + "value": "100 - 200 µg" + }, + { + "name": "Heavy", + "value": "200 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 4, + "name": "1P-LSD", + "aliases": [ + "1p", + "1plsd" + ], + "aliasesStr": "1p,1plsd", + "url": "https://psychonautwiki.org/wiki/1P-LSD", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_1PLSD.shtml", + "summary": "An LSD analogue which appears to be slightly more potent with a shorter duration. Its effects are reported to be extremely similar to LSD, and thus far seems to be similarly safe. Released in late 2014, It has quickly become a highly popular research chemical due to its implicit legality, similarity to LSD and wide availability on the Internet.", + "reagents": "Marquis: Slow Purple. | Mecke: Brown. | Mandelin: No colour change. | Froehde: No colour change. | Liebermann: No colour change. | Ehrlich's Reagent: No colour change. | Gallic Acid: Brown.", + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "extremely low toxicity relative to dose" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 µg" + }, + { + "name": "Light", + "value": "25 - 75 µg" + }, + { + "name": "Common", + "value": "75 - 150 µg" + }, + { + "name": "Strong", + "value": "150 - 300 µg" + }, + { + "name": "Heavy", + "value": "300 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 5, + "name": "2-AI", + "aliases": [ + "2-aminoindan", + "2-aminoindane", + "2ai" + ], + "aliasesStr": "2-aminoindan,2-aminoindane,2ai", + "url": "https://psychonautwiki.org/wiki/2-Aminoindane", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2Aminoindan.shtml", + "summary": "Short acting stimulant that is sometimes compared to the likes of Methamphetamine. It is a rigid analogue of Amphetamine, and also partially substitutes for the prior in rat discrimination studies.", + "reagents": "Marquis: Orange > Brown. | Mecke: Yellow. | Mandelin: Blue. | Liebermann: Yellow Brown. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Aminoindane" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 6, + "name": "2-Chloroephenidine", + "aliases": [ + "2-cl-ephenidine", + "2chloroephenidine", + "2clephenidine" + ], + "aliasesStr": "2-cl-ephenidine,2chloroephenidine,2clephenidine", + "url": "https://drugs.tripsit.me/2-chloro-ephenidine", + "experiencesUrl": null, + "summary": "Analogue of Ephenidine. Very little is known about this quite obscure compound. Very likely to exhibit dissociative effects, and is slightly less potent than the parent drug Ephenidine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "100-130mg" + }, + { + "name": "Common", + "value": "130-175mg" + }, + { + "name": "Strong", + "value": "175-200mg" + }, + { + "name": "Heavy", + "value": "200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 7, + "name": "2-DPMP", + "aliases": [ + "2-desoxypiperadol", + "2dpmp", + "desoxypipradol", + "desoxypipradrol", + "ivory wave" + ], + "aliasesStr": "2-desoxypiperadol,2dpmp,desoxypipradol,desoxypipradrol,ivory wave", + "url": "https://psychonautwiki.org/wiki/Desoxypipradrol", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Desoxypipradrol_.shtml", + "summary": "A very potent stimulant that is a NDRI. Developed by Novartis in the 1950s, to treat narcolepsy and ADHD, however dropped when Methylphenidate was produced a few years later, which was seen as superior due to its shorter T½. 2-DPMP Half life 16-20 hours. Warning: subjective reports suggest this drug is caustic to the nasal mucosa and may cause damage to the nasal cavity.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_piperidines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 6 mg" + }, + { + "name": "Strong", + "value": "6 - 8 mg" + }, + { + "name": "Heavy", + "value": "8 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "16 - 72 hours" + }, + { + "name": "Onset", + "value": "1 - 4 hours" + }, + { + "name": "Peak", + "value": "9 - 30 hours" + }, + { + "name": "Offset", + "value": "6 - 40 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Common", + "value": "1.5 - 3.5 mg" + }, + { + "name": "Strong", + "value": "3.5 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 72 hours" + }, + { + "name": "Onset", + "value": "15 - 240 minutes" + }, + { + "name": "Come up", + "value": "2 - 6 hours" + }, + { + "name": "Peak", + "value": "6 - 30 hours" + }, + { + "name": "Offset", + "value": "6 - 40 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 8, + "name": "2-FA", + "aliases": [ + "2-fluoroamphetamine", + "2-fmp", + "2fa" + ], + "aliasesStr": "2-fluoroamphetamine,2-fmp,2fa", + "url": "https://psychonautwiki.org/wiki/2-FA", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2Fluoroamphetamine.shtml", + "summary": "Stimulant drug of the amphetamine family. Reported as having effects similar to those of Dextroamphetamine, but with a milder euphoria and a comparatively smoother comedown. Has a shorter duration and less empathogenic effect-profile as compared with 4-FA. Thought to produce less neurotoxic metabolites compared to amphetamine.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 10 days" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "2-5 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "2-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 9, + "name": "2-FDCK", + "aliases": [ + "2-fk", + "2-fl-2'-oxo-pcm", + "2-fluorodeschloroketamine", + "2-fluoroketamine", + "2f-dck", + "2f-ket", + "2f-ketamine", + "2fdck", + "2fket", + "fluoroketamine" + ], + "aliasesStr": "2-fk,2-fl-2'-oxo-pcm,2-fluorodeschloroketamine,2-fluoroketamine,2f-dck,2f-ket,2f-ketamine,2fdck,2fket,fluoroketamine", + "url": "https://psychonautwiki.org/wiki/2-Fluorodeschloroketamine", + "experiencesUrl": null, + "summary": "Dissociative anesthetic of the arylcyclohexylamine class. Seemingly on par with ketamine in dosage. Longer onset than the prior.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 140 mg" + }, + { + "name": "Heavy", + "value": "140 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 5.0 hours" + }, + { + "name": "Onset", + "value": "15 - 50 minutes" + }, + { + "name": "Peak", + "value": "50 - 100 minutes" + }, + { + "name": "After effects", + "value": "3 - 8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 45 mg" + }, + { + "name": "Common", + "value": "45 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 175 mg" + }, + { + "name": "Heavy", + "value": "175 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 3 hours" + }, + { + "name": "Onset", + "value": "1 - 3 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 10, + "name": "2-FEA", + "aliases": [ + "2-fluoroethylamphetamine" + ], + "aliasesStr": "2-fluoroethylamphetamine", + "url": "https://psychonautwiki.org/wiki/2-FEA", + "experiencesUrl": null, + "summary": "Stimulant closely related to 2-FMA. Presumably slightly less potent than the prior. Toxicology and the likes are pretty much completely unknown. Tread with caution.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2.5 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 11, + "name": "2-FMA", + "aliases": [ + "2fma" + ], + "aliasesStr": "2fma", + "url": "https://psychonautwiki.org/wiki/2-FMA", + "experiencesUrl": null, + "summary": "A long-acting stimulant often compared to lisdexamphetamine. Thought to lack some of amphetamine's neurotoxic metabolites. Very functional, and for this reason it is commonly used for studying.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 9 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 40 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "10 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 12, + "name": "2-Me-DMT", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/2-me-dmt", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2MeDMT.shtml", + "summary": "Also known as 2,N,N-TMT, this drug was first synthesised by Alexander Shulgin. Described as a very mild psychedelic of similar subjective effects to other tryptamines. Reported as having an unusual and unpredictable dose curve, it is recommended to start low with this drug.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "30-50mg" + }, + { + "name": "Common", + "value": "50-75mg" + }, + { + "name": "Strong", + "value": "75-100mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-90 minutes" + }, + { + "name": "Duration", + "value": "3-8 hours" + }, + { + "name": "After effects", + "value": "1-5 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "15-40 minutes" + }, + { + "name": "Duration", + "value": "3-8 hours" + }, + { + "name": "After effects", + "value": "1-5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 13, + "name": "2-MEC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/2-mec", + "experiencesUrl": null, + "summary": "Cathinone which some users report to feel like a weaker MDMA with a shorter onset.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-200mg" + }, + { + "name": "Strong", + "value": "200-350mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-250mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 14, + "name": "2M2B", + "aliases": [ + "2-methyl-2-butanol" + ], + "aliasesStr": "2-methyl-2-butanol", + "url": "https://psychonautwiki.org/wiki/2M2B", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2Methyl2Butanol.shtml", + "summary": "A tertiary alcohol that has sedative, hypnotic, and anxiolytic effects. It is also roughly 20x more potent than Ethanol by weight.", + "reagents": null, + "classes": { + "chemical": [ + "Alcohol" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "GABA", + "depressants" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mL" + }, + { + "name": "Light", + "value": "1 - 5 mL" + }, + { + "name": "Common", + "value": "5 - 10 mL" + }, + { + "name": "Strong", + "value": "10 - 15 mL" + }, + { + "name": "Heavy", + "value": "15 mL +", + "note": "There have been unconsciousness and deaths reported at as low as 18 mL respective 29 mL." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "10 - 50 minutes" + }, + { + "name": "Peak", + "value": "6 - 8 hours" + }, + { + "name": "Offset", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 15, + "name": "2-MA", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/2-methylamphetamine", + "experiencesUrl": null, + "summary": "Also known as Ortetamine, this rarely seen amphetamine is approximately 1/10th as potent as dextroamphetamine. Little information exists regarding its safety or effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-30mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Strong", + "value": "50-70mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Insufflated minutes" + }, + { + "name": "Duration", + "value": "Insufflated hours" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 16, + "name": "2-MMC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/2-mmc", + "experiencesUrl": null, + "summary": "A cathinone, yet the effects are noted more of the likes of 2-FA or amphetamine. Which apparently left people dissapointed.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "20-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-135mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "2-8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-40mg" + }, + { + "name": "Strong", + "value": "40-80mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "2-15 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 17, + "name": "2-MPPP", + "aliases": [ + "n-piperidinecathinone" + ], + "aliasesStr": "n-piperidinecathinone", + "url": "https://drugs.tripsit.me/2-mppp", + "experiencesUrl": null, + "summary": "A novel stimulant that is similar to methcathinone.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-150mg" + }, + { + "name": "Heavy", + "value": "150mg+." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "15-30mg" + }, + { + "name": "Common", + "value": "30-60mg" + }, + { + "name": "Strong", + "value": "60-110mg" + }, + { + "name": "Heavy", + "value": "110mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Rectal", + "duration": [ + { + "name": "Onset", + "value": "10-15 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 18, + "name": "2-NMC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/2-nmc", + "experiencesUrl": null, + "summary": "Inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 19, + "name": "2-PA", + "aliases": [ + "2-phenylacetamide" + ], + "aliasesStr": "2-phenylacetamide", + "url": "https://drugs.tripsit.me/2-pa", + "experiencesUrl": null, + "summary": "Amphetamine with the alpha-methyl replaced by ketone. Very few reports. Also no information on the safety of this compound. As always treat with caution.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50-100mg" + }, + { + "name": "Heavy", + "value": "100+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 20, + "name": "2-PTA", + "aliases": [ + "2-(p-tolyl)acetamide", + "4-methyl-2-pa" + ], + "aliasesStr": "2-(p-tolyl)acetamide,4-methyl-2-pa", + "url": "https://drugs.tripsit.me/2-pta", + "experiencesUrl": null, + "summary": "4-Methylamphetamine with the alpha-methyl replaced by ketone. Very few reports. Also no information of the safety of this compound. As always treat with caution.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Strong", + "value": "40-80mg" + }, + { + "name": "Heavy", + "value": "80+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-25 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 21, + "name": "25B-NBOH", + "aliases": [ + "25bnboh", + "2c-b-nboh", + "2cb-nboh", + "nboh-2cb" + ], + "aliasesStr": "25bnboh,2c-b-nboh,2cb-nboh,nboh-2cb", + "url": "https://psychonautwiki.org/wiki/25B-NBOH", + "experiencesUrl": null, + "summary": "A phenethylamine psychedelic and stimulant derivative of 2C-B, this compound is related to and has similar effects to 25b-NBOMe. It is significantly more potent than 2C-B but less potent than 25B-NBOMe. Overdoses of NBOH compounds may cause dangerous vasoconstriction. May induce uncomfortable body load.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Sublingually", + "dosage": [ + { + "name": "Light", + "value": "200-400ug" + }, + { + "name": "Common", + "value": "400-800ug" + }, + { + "name": "Strong", + "value": "800ug-1mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "4-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 22, + "name": "25B-NBOMe", + "aliases": [ + "25b" + ], + "aliasesStr": "25b", + "url": "https://psychonautwiki.org/wiki/25B-NBOMe", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_25BNBOMe.shtml", + "summary": "Psychedelic Phenethylamine, active in the lower microgram range, that is not active orally.", + "reagents": "Marquis: Dark Green. | Mecke: Dark Green. | Mandelin: Red and Green. | Froehde: Yellow | Liebermann: Yellow > Black. | Ehrlich's Reagent: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "100 - 300 µg" + }, + { + "name": "Common", + "value": "300 - 500 µg" + }, + { + "name": "Strong", + "value": "500 - 700 µg" + }, + { + "name": "Heavy", + "value": null, + "note": "25B-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "25 µg" + }, + { + "name": "Light", + "value": "50 - 200 µg" + }, + { + "name": "Common", + "value": "200 - 350 µg" + }, + { + "name": "Strong", + "value": "350 - 500 µg" + }, + { + "name": "Heavy", + "value": null, + "note": "25B-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 23, + "name": "25C-NBOH", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/25C-NBOH", + "experiencesUrl": null, + "summary": "A phenethylamine psychedelic and stimulant derivative of 2C-C, this compound is related and has similar effects to 25c-NBOMe. It is significantly more potent than 2C-C but less potent than 25c-NBOMe. Overdoses of NBOH compounds may cause dangerous vasoconstriction. May induce uncomfortable body load.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "100 µg" + }, + { + "name": "Light", + "value": "250 - 500 µg" + }, + { + "name": "Common", + "value": "500 - 750 µg" + }, + { + "name": "Strong", + "value": "750 - 1000 µg" + }, + { + "name": "Heavy", + "value": null, + "note": "25C-NBOH may be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "3 - 6 days" + } + ] + } + ], + "interactions": null + }, + { + "id": 24, + "name": "25C-NBOMe", + "aliases": [ + "25c", + "2c-c-nbome", + "2c-nbome", + "cimbi-82", + "nbome-2c-c" + ], + "aliasesStr": "25c,2c-c-nbome,2c-nbome,cimbi-82,nbome-2c-c", + "url": "https://psychonautwiki.org/wiki/25C-NBOMe", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_25CNBOMe.shtml", + "summary": "A relatively new and popular research chemical. A short acting psychedelic related to 2C-C with similar effects to LSD, though more visual with less of a 'head-trip.' Frequently mis-sold as LSD. Causes an uncomfortable body load and has caused several deaths even within regular dose ranges.", + "reagents": "Marquis: Slow Purple. | Mecke: Brown. | Mandelin: No colour change. | Froehde: Yellow. | Liebermann: Yellow > Black. | Ehrlich's Reagent: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "100 - 300 µg" + }, + { + "name": "Common", + "value": "300 - 700 µg" + }, + { + "name": "Strong", + "value": "700 - 1000 µg" + }, + { + "name": "Heavy", + "value": null, + "note": "25C-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 10 hours" + }, + { + "name": "Onset", + "value": "0 - 15 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 25, + "name": "25D-NBOMe", + "aliases": [ + "25d", + "2c-d-nbome" + ], + "aliasesStr": "25d,2c-d-nbome", + "url": "https://psychonautwiki.org/wiki/25D-NBOMe", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_25DNBOMe.shtml", + "summary": "Uncommon analogue of 2C-D. Extremely potent psychedelic with stimulating qualities. Could cause dangerous vasoconstriction at high doses. May induce uncomfortable body load.", + "reagents": "Marquis: Orange > Red. | Mecke: Brown > Green. | Mandelin: Red and Green. | Liebermann: Yellow > Black. | Simon's: Red > Brown. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": [ + "psychedelics" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "300 µg" + }, + { + "name": "Light", + "value": "300 - 800 µg" + }, + { + "name": "Common", + "value": "800 - 1000 µg" + }, + { + "name": "Strong", + "value": "1000 - 1200 µg" + }, + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal at heavy doses.[4][5]" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "> 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal when insufflated.[4][5][6] It is strongly discouraged." + } + ], + "duration": null + } + ], + "interactions": null + }, + { + "id": 26, + "name": "25E-NBOMe", + "aliases": [ + "25e" + ], + "aliasesStr": "25e", + "url": "https://drugs.tripsit.me/25e-nbome", + "experiencesUrl": null, + "summary": "A potent psychedelic phenethylamine and derivative of 2C-E, usually sold on blotters. May be mis-sold as LSD. Effects include vivid hallucinations, stimulation, heavy body load and vasoconstriction. At high doses vasoconstriction can endanger life, exercise caution.", + "reagents": "Marquis: Red > Yellow. | Mecke: Green. | Mandelin: Red. | Ehrlich: No colour change.", + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50-100ug" + }, + { + "name": "Light", + "value": "50-200ug" + }, + { + "name": "Common", + "value": "200-400ug" + }, + { + "name": "Strong", + "value": "400-800ug." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-60 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "2-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 27, + "name": "25G-NBOMe", + "aliases": [ + "25g", + "25gnbome" + ], + "aliasesStr": "25g,25gnbome", + "url": "https://drugs.tripsit.me/25g-nbome", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_25GNBOMe.shtml", + "summary": "A rare psychedelic stimulant and bomamine. A derivative of 2C-G, but far more potent. Likely to have hallucinogenic, stimulant and vasoconstrictive properties which may be dangerous at high doses. A heavy body load is to be expected.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Buccal/Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "500ug" + }, + { + "name": "Light", + "value": "1000-1500ug" + }, + { + "name": "Common", + "value": "1500-2000ug" + }, + { + "name": "Strong", + "value": "2000ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-50 minutes" + }, + { + "name": "Duration", + "value": "5-7 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 28, + "name": "25H-NBOMe", + "aliases": [ + "25-h-nbome", + "25h" + ], + "aliasesStr": "25-h-nbome,25h", + "url": "https://drugs.tripsit.me/25h-nbome", + "experiencesUrl": null, + "summary": "A rare psychedelic stimulant and bomamine. A derivative of 2C-H, but many times more potent. Likely to have hallucinogenic, stimulant and vasoconstrictive properties which may be dangerous at high doses. A heavy body load is to be expected.", + "reagents": "Marquis: Light Brown > Brown. | Mecke: Yellow > Green/Brown. | Mandelin: Green/Brown > Orange. | Simon's: Orange > Black.", + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 29, + "name": "25I-NBF", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/25i-nbf", + "experiencesUrl": null, + "summary": "Is a derivate of the psychedelic 2C-I. Was sold breifly in a few countries before being banned. Based purely on the pharmacological evidence it'll be between 6-8x less potent than it's parent compound 25I-NBOMe.", + "reagents": "Marquis: Dark Green. | Mecke: Orange > Black. | Mandelin: Orange > Black. | Froehde: Orange > Black. | Liebermann: Orange > Black. | Ehrlich: No colour change. | Gallic Acid: Orange > Black.", + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 30, + "name": "25I-NBMD", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/25i-nbmd", + "experiencesUrl": null, + "summary": "A psychedelic phenethylamine that is related to the 25X-NBOMe series which in turn makes it related to the 2C-X series. Quite potent substance.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Light", + "value": "800-1500ug" + }, + { + "name": "Common", + "value": "1500-2000ug" + }, + { + "name": "Strong", + "value": "2000-3000ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 31, + "name": "25I-NBOH", + "aliases": [ + "cimbi-27", + "nboh-2ci" + ], + "aliasesStr": "cimbi-27,nboh-2ci", + "url": "https://psychonautwiki.org/wiki/25I-NBOH", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_25INBOH.shtml", + "summary": "A phenethylamine psychedelic and stimulant derivative of 2C-I, this compound is related and has similar effects to 25i-NBOMe. It is significantly more potent than 2C-I but less potent than 25i-NBOMe. Overdoses of NBOH compounds may cause dangerous vasoconstriction. May induce uncomfortable body load.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "200 - 500 µg" + }, + { + "name": "Common", + "value": "500 - 900 µg" + }, + { + "name": "Strong", + "value": "900 - 1400 µg" + }, + { + "name": "Heavy", + "value": null, + "note": "25I-NBOH may be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3.5 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2.5 hours" + }, + { + "name": "After effects", + "value": "3 - 12 days" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "166ug-416ug" + }, + { + "name": "Light", + "value": "416ug-766ug" + }, + { + "name": "Common", + "value": "800-1400ug" + }, + { + "name": "Strong", + "value": "1400ug-2000ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 32, + "name": "25I-NBOMe", + "aliases": [ + "2-c-i-nbome", + "25-i", + "25i", + "cimbi-5" + ], + "aliasesStr": "2-c-i-nbome,25-i,25i,cimbi-5", + "url": "https://psychonautwiki.org/wiki/25I-NBOMe", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_25INBOMe.shtml", + "summary": "A relatively new and popular research chemical with psychedelic properties. Users report an uncomfortable body load with very strong visuals, though with less of a mental aspect than most psychedelics. Commonly mis-sold as LSD, since it is much cheaper to produce. Is considered quite unsafe, and has caused several deaths at 'regular' doses.", + "reagents": "Marquis: Orange > Black. | Mecke: Brown > Black. | Mandelin: Brown > Black. | Froehde: Yellow | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 week", + "zero": "2 weeks" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "200 - 500 µg" + }, + { + "name": "Common", + "value": "500 - 700 µg" + }, + { + "name": "Strong", + "value": "700 - 1000 µg" + }, + { + "name": "Heavy", + "value": null, + "note": "25I-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 120 minutes" + }, + { + "name": "Come up", + "value": "30 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "3 - 6 days" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "200 - 500 µg" + }, + { + "name": "Common", + "value": "500 - 700 µg" + }, + { + "name": "Strong", + "value": "700+ µg" + }, + { + "name": "Heavy", + "value": null, + "note": "25I-NBOMe can be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 120 minutes" + }, + { + "name": "Offset", + "value": "120 - 180 minutes" + }, + { + "name": "After effects", + "value": "1 - 7 days" + } + ] + } + ], + "interactions": null + }, + { + "id": 33, + "name": "25iP-NBOMe", + "aliases": [ + "25ip" + ], + "aliasesStr": "25ip", + "url": "https://drugs.tripsit.me/25ip-nbome", + "experiencesUrl": null, + "summary": "Almost unheard-of bomamine analogue of 2C-iP. Extremely potent psychedelic with stimulating qualities. May cause potentially dangerous vasoconstriction at high doses. May induce uncomfortable body load.", + "reagents": "Marquis: Red. | Mecke: Green. | Mandelin: Red and Green. | Froehde: Green. | Liebermann: Yellow > Brown. | Ehrlich: No colour change.", + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "250ug" + }, + { + "name": "Light", + "value": "300-750ug" + }, + { + "name": "Common", + "value": "750-1000ug" + }, + { + "name": "Strong", + "value": "1000-1500ug" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "5-7 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 34, + "name": "25N-NBOMe", + "aliases": [ + "2-c-n-nbome", + "25n" + ], + "aliasesStr": "2-c-n-nbome,25n", + "url": "https://psychonautwiki.org/wiki/25N-NBOMe", + "experiencesUrl": null, + "summary": "A rare, highly potent and yellow psychedelic phenethylamine and derivative of 2C-N. Effects are similar to other NBOMe compounds, with hallucinations, intense body load, stimulation and vasoconstriction. At high doses vasoconstriction can be dangerous, exercise caution.", + "reagents": "Marquis: Red > Brown. | Mecke: Blue > Black. | Mandelin: Blue > Black. | Froehde: Brown. | Liebermann: Brown. | Simon's: Red > Brown. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "< 100 µg" + }, + { + "name": "Light", + "value": "100 - 300 µg" + }, + { + "name": "Common", + "value": "300 - 800 µg" + }, + { + "name": "Strong", + "value": "800 - 1300 μg" + }, + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal at heavy doses.[4][5]" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "5 - 10 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Heavy", + "value": null, + "note": "The NBOMe series can be fatal when insufflated.[4][5][6] It is strongly discouraged." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + } + ] + }, + { + "name": "Sublingual/Buccal", + "dosage": [ + { + "name": "Light", + "value": "100-300ug" + }, + { + "name": "Common", + "value": "300-800ug" + }, + { + "name": "Strong", + "value": "800-1300ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-75 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 35, + "name": "25P-NBOMe", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/25p-nbome", + "experiencesUrl": null, + "summary": "A rare potent psychedelic drug with similar effects and risks to others in the NBOMe class. Yet no trip reports... when the substance was first sold in mid-late 2012, and resurfaced in early 2015.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100-250ug" + }, + { + "name": "Light", + "value": "250-450ug" + }, + { + "name": "Common", + "value": "450-700ug" + }, + { + "name": "Strong", + "value": "700-1500ug" + } + ], + "duration": [ + { + "name": "Onset", + "value": "25-40 minutes" + }, + { + "name": "Duration", + "value": "7-14 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 36, + "name": "25T-2-NBOMe", + "aliases": [ + "25t2-nbome" + ], + "aliasesStr": "25t2-nbome", + "url": "https://drugs.tripsit.me/25t-2-nbome", + "experiencesUrl": null, + "summary": "A potent serotonin receptor agonist at the 5-HT2a receptor that is of the NBOMe drug class. It is a hallucinogenic and psychedelic with limited recorded human use.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Light", + "value": "100-300ug" + }, + { + "name": "Common", + "value": "300-600ug" + }, + { + "name": "Strong", + "value": "600-1000ug." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "2-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 37, + "name": "25T-4-NBOMe", + "aliases": [ + "25t4-nbome" + ], + "aliasesStr": "25t4-nbome", + "url": "https://drugs.tripsit.me/25t-4-nbome", + "experiencesUrl": null, + "summary": "A psychedelic RC of the NBOMe class of drugs that is expected to cause hallucinations. Limited human use has been recorded on this drug and caution should be used with dosing.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Light", + "value": "150-300ug" + }, + { + "name": "Common", + "value": "300-750ug" + }, + { + "name": "Strong", + "value": "750-1200ug." + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-45 minutes" + }, + { + "name": "Duration", + "value": "5-9 hours" + }, + { + "name": "After effects", + "value": "2-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 38, + "name": "2C-B", + "aliases": [ + "2-cb", + "2cb", + "bees", + "nexus", + "tusi" + ], + "aliasesStr": "2-cb,2cb,bees,nexus,tusi", + "url": "https://psychonautwiki.org/wiki/2C-B", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CB.shtml", + "summary": "A popular psychedelic in the phenethylamine family. Provides empathic experiences at lower doses and strong visual and psychedelic experiences at higher doses. Commonly used as a party drug as it is more clear-headed than most psychedelics. 2C-B has been in use since the early 1990s", + "reagents": "Marquis: Yellow > Green. | Mecke: Yellow > Green/Brown. | Mandelin: Green. | Froehde: Yellow > Green. | Liebermann: Yellow > Black. | Simon's No colour change or Purple. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "40 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated/Plugged", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-30mg" + }, + { + "name": "Heavy", + "value": "30mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "2-4 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "1-10 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + }, + { + "name": "Plugged", + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 39, + "name": "2C-B-AN", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/2c-b-an", + "experiencesUrl": null, + "summary": "2C-B-AN is a novel prodrug for 2C-B.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "30-45mg" + }, + { + "name": "Common", + "value": "45-70mg" + }, + { + "name": "Strong", + "value": "70-100mg" + }, + { + "name": "Heavy", + "value": "100+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "40-75 minutes" + }, + { + "name": "Duration", + "value": "5-9 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 40, + "name": "2C-B-FLY", + "aliases": [ + "2cb-fly", + "2cbfly" + ], + "aliasesStr": "2cb-fly,2cbfly", + "url": "https://psychonautwiki.org/wiki/2C-B-FLY", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CBFly.shtml", + "summary": "Psychedelic phenethylamine that is the dihydrodifuran analog of 2C-B.", + "reagents": "Marquis: Yellow > Brown Green. | Mecke: Yellow > Brown Green. | Mandelin: Brown.", + "classes": { + "chemical": [ + "Substituted_phenethylamines", + "Substituted_benzofurans" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 18 mg" + }, + { + "name": "Strong", + "value": "18 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 41, + "name": "2C-B-FLY-NBOMe", + "aliases": [ + "2cbflynbome" + ], + "aliasesStr": "2cbflynbome", + "url": "https://drugs.tripsit.me/2c-b-fly-nbome", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "100-200ug" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 42, + "name": "2C-C", + "aliases": [ + "2cc" + ], + "aliasesStr": "2cc", + "url": "https://psychonautwiki.org/wiki/2C-C", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CC.shtml", + "summary": "A short-acting psychedelic research chemical of the 2c-x family. Often described as being less stimulating than the other 2c-x, and is a relatively unique psychedelic in this respect.", + "reagents": "Marquis: Yellow > Green Brown. | Mecke: Yellow Green > Brown. | Mandelin: Orange > Yellow. | Froehde: Yellow > Green. | Liebermann: Yellow > Black > Clear. | Simon's: Pink > Brown. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 43, + "name": "2C-D", + "aliases": [ + "2c-m", + "2cd", + "2cm", + "le-25" + ], + "aliasesStr": "2c-m,2cd,2cm,le-25", + "url": "https://psychonautwiki.org/wiki/2C-D", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CD.shtml", + "summary": "A fairly generic psychedelic famed for being usable as \"psychedelic tofu\". Little character of its own but pleasant in combinations.", + "reagents": "Marquis: Yellow > Brown. | Mecke: Green > Brown. | Mandelin: Green/Yellow. | Simon's Brown > Red. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "0.5 - 1.5 hours" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 44, + "name": "2C-E", + "aliases": [ + "2ce", + "aquarust", + "eternity" + ], + "aliasesStr": "2ce,aquarust,eternity", + "url": "https://psychonautwiki.org/wiki/2C-E", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CE.shtml", + "summary": "An intense psychedelic drug with very strong visuals, sometimes criticised for its relatively uncomfortable body load. Otherwise, effects are comparable to other 2c-x drugs.", + "reagents": "Marquis: Yellow-Pale Brown. | Mecke: Yellow > Brown. | Mandelin: Yellow-Green. | Froehde: Yellow. | Liebermann: Yellow > Black. | Simon's: No colour change. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "1 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 7 mg" + }, + { + "name": "Strong", + "value": "7 - 14 mg" + }, + { + "name": "Heavy", + "value": "14 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 2 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 45, + "name": "2C-G", + "aliases": [ + "2cg" + ], + "aliasesStr": "2cg", + "url": "https://drugs.tripsit.me/2c-g", + "experiencesUrl": null, + "summary": "Extremely rare drug of the 2C-X family. An extremely long lasting substance. Is nearly as potent as its amphetamine counter-part, Ganesha. Yet is said to have very little visual activity.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "20-25mg" + }, + { + "name": "Common", + "value": "25-30mg" + }, + { + "name": "Strong", + "value": "30mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "15-35 hours" + }, + { + "name": "After effects", + "value": "1-72 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 46, + "name": "2C-H", + "aliases": [ + "dmpea" + ], + "aliasesStr": "dmpea", + "url": "https://psychonautwiki.org/wiki/2C-H", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3-5 days", + "zero": "7-10 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "??? - ???" + } + ], + "duration": [ + { + "name": "Total", + "value": "??? - ???" + } + ] + } + ], + "interactions": null + }, + { + "id": 47, + "name": "2C-I", + "aliases": [ + "2ci" + ], + "aliasesStr": "2ci", + "url": "https://psychonautwiki.org/wiki/2C-I", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CI.shtml", + "summary": "A psychedelic similar to the more well-known 2C-B. Users frequently report very vivid and bright open-eye visuals and more mild closed-eye visuals compared to 2C-B and other drugs in the 2C family. Can also be more stimulating than 2C-B along with having a slight body load for some users. Less safe at high doses compared to 2C-B", + "reagents": "Marquis: Yellow > Green/Blue. | Mecke: Brown > Black. | Mandelin: (Pale) Brown > Black. | Simon's: Red > Orange. | Ehrlich: Brown.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3-5 days", + "zero": "7-10 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.5-2mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-120 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "4-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 48, + "name": "2C-IP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/2c-ip", + "experiencesUrl": null, + "summary": "Isopropyl analog (branched analog) of 2C-P with a slightly shorter duration and lower potency.", + "reagents": "Marquis: Orange > Red. | Mecke: Yellow > Brown. | Mandelin: Green. | Ehrlich: No colour change.", + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "none", + "dosage": [ + { + "name": "Threshold", + "value": "5mg" + }, + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Heavy", + "value": "30-45mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "12-16 hours" + }, + { + "name": "After effects", + "value": "4-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 49, + "name": "2C-N", + "aliases": [ + "2cn" + ], + "aliasesStr": "2cn", + "url": "https://drugs.tripsit.me/2c-n", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CN.shtml", + "summary": "A relatively uncommon and short-acting psychedelic phenethylamine of the 2C-x family. It behaves much like other 2C-x drugs, but is unique in that it is a yellowish golden-coloured salt. Described by some, namely Shulgin, as being quite underwhelming.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "100mg" + }, + { + "name": "Common", + "value": "100-125mg" + }, + { + "name": "Strong", + "value": "125-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 50, + "name": "2C-P", + "aliases": [ + "2cp" + ], + "aliasesStr": "2cp", + "url": "https://psychonautwiki.org/wiki/2C-P", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CP.shtml", + "summary": "A synthetic phenylethlyamine that is sometimes compared in effects to 2C-E, yet with a much longer duration. With a much more pronouced bodyload. Is one of the most potent of the 2C-X series.", + "reagents": "Marquis: Yellow. | Mecke: Green > Brown. | Mandelin: Green. | Froehde: Green. | Liebermann: Green. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "low potential for abuse and dependence", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 16 mg" + }, + { + "name": "Heavy", + "value": "16 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 20 hours" + }, + { + "name": "Onset", + "value": "1 - 3 hours" + }, + { + "name": "Come up", + "value": "2 - 4 hours" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "8 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-5mg" + }, + { + "name": "Strong", + "value": "5-10mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "10-16 hours" + }, + { + "name": "After effects", + "value": "6-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 51, + "name": "2C-T", + "aliases": [ + "2ct", + "tesseract" + ], + "aliasesStr": "2ct,tesseract", + "url": "https://psychonautwiki.org/wiki/2C-T", + "experiencesUrl": null, + "summary": "A very rare psychedelic phenylethylamine, that is quite lovely.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "no negative health effects attributed to trying this drug" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 120 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + }, + { + "name": "Peak", + "value": "30 - 115 minutes" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 52, + "name": "2C-T-2", + "aliases": [ + "2ct2", + "rosy" + ], + "aliasesStr": "2ct2,rosy", + "url": "https://psychonautwiki.org/wiki/2C-T-2", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CT2.shtml", + "summary": "An unusual psychedelic with similar effects to 2C-B and a slightly longer duration, but maligned because of some deaths in the 2000s. Also similar to 2c-t-7, but with a shorter duration. Potentially unsafe with stimulants and empathogens.", + "reagents": "Marquis: Fizzes Pale Orange. | Mecke: Orange > Purple. | Mandelin: Purple. | Froehde: Orange > Purple | Liebermann: Red or Purple. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "no negative health effects attributed to trying this drug" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "25 - 30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 25 mg" + }, + { + "name": "Heavy", + "value": "25+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 53, + "name": "2C-T-21", + "aliases": [ + "aurora" + ], + "aliasesStr": "aurora", + "url": "https://psychonautwiki.org/wiki/2C-T-21", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CT21.shtml", + "summary": "A rare psychedelic phenethylamine.", + "reagents": "Marquis: Fizzes Light Orange. | Mecke: Dark Purple. | Simon's: Greenish Blue.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 12 hours" + }, + { + "name": "Onset", + "value": "90 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 54, + "name": "2C-T-4", + "aliases": [ + "2-ct4", + "2c-t4", + "2ct-4", + "2ct4" + ], + "aliasesStr": "2-ct4,2c-t4,2ct-4,2ct4", + "url": "https://drugs.tripsit.me/2c-t-4", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CT4.shtml", + "summary": "A psychedelic phenethylamine that has a longer onset and duration compared to the more common 2C-T-x (2 and 7).", + "reagents": "Marquis: Pale Orange. | Mandelin: Orange (Or Purple). | Liebermann: Purple. | Ehrlich: Purple.", + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5-6mg" + }, + { + "name": "Light", + "value": "6-10mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15-20mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "10-18 hours" + }, + { + "name": "After effects", + "value": "4-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 55, + "name": "2C-T-7", + "aliases": [ + "2ct7", + "7th heaven", + "beautiful", + "blue mystic" + ], + "aliasesStr": "2ct7,7th heaven,beautiful,blue mystic", + "url": "https://psychonautwiki.org/wiki/2C-T-7", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_2CT7.shtml", + "summary": "A relatively uncommon psychedelic phenethylamine and possible MAOI. Long lasting, an possesses an unpredictable dosage curve. Questionable safety in combination with most things.", + "reagents": "Marquis: Fizzes Pale Orange. | Mecke: Red > Purple. | Mandelin: Red > Purple. | Froehde: Violet Orange | Liebermann: Deep Purple. | Simon's Red > Brown. | Ehrlich: No colour change.", + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "60 - 90 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 - 25 mg", + "note": "2C-T-7 has been fatal when insufflated at heavy doses of 30mg or higher." + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 56, + "name": "3,4-CTMP", + "aliases": [ + "3,4-dichloromethylphenidate", + "34ctmp" + ], + "aliasesStr": "3,4-dichloromethylphenidate,34ctmp", + "url": "https://psychonautwiki.org/wiki/3,4-CTMP", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_34Dichloromethylphenidate.shtml", + "summary": "A strong stimulant, NDRI and analogue of methylphenidate. Has increased in popularity in recent years. Said to be seven times more potent than methylphenidate but with a slower onset, however discrimination studies have found it to be more addictive than cocaine.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 2 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 18 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 57, + "name": "3,6-DMPM", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/3,6-dmpm", + "experiencesUrl": null, + "summary": "Stimulant that is related to Phenmetrazine. Nearly no information on dose or effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 58, + "name": "3-CMC", + "aliases": [ + "3cmc" + ], + "aliasesStr": "3cmc", + "url": "https://drugs.tripsit.me/3-cmc", + "experiencesUrl": null, + "summary": "A rarely seen halogenated cathinone drug. Likely to be a stimulant, possibly an entactogen. (Note: The amphetamine analogue of this drug, 4-CA, is a highly dangerous neurotoxin, no data about the safety of this one, but should likely be avoided)", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "30-60mg" + }, + { + "name": "Common", + "value": "60-100mg" + }, + { + "name": "Strong", + "value": "100-180mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "4-12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-80mg" + }, + { + "name": "Strong", + "value": "80-100mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "3-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 59, + "name": "3-FA", + "aliases": [ + "3fa", + "pal-353" + ], + "aliasesStr": "3fa,pal-353", + "url": "https://psychonautwiki.org/wiki/3-FA", + "experiencesUrl": null, + "summary": "A stimulant that is close to equipotent with methamphetamine and acts as a monoamine releasing agent , but has more selectivity for dopamine/noradrenaline over serotonin.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 10 days" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 60, + "name": "3-FEA", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/3-FEA", + "experiencesUrl": null, + "summary": "A novel fluorinated amphetamine with serotonergic properties. Effects are similar to 4-FA, in that it provides slight dopamine and norepinephrine release or reuptake inhibition, as well as serotonin release and reuptake inhibition. Effects on the serotonin side are more pronounced than dopamine and norepinephrine, the latter two being almost negligibly.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "2 - 3 days", + "zero": "3-7 days" + }, + "crossTolerances": [ + "dopamine", + "serotonin|serotonergic", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 60 mg" + }, + { + "name": "Strong", + "value": "50 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 61, + "name": "3-FMA", + "aliases": [ + "3fma" + ], + "aliasesStr": "3fma", + "url": "https://psychonautwiki.org/wiki/3-FMA", + "experiencesUrl": null, + "summary": "Stimulant drug in the amphetamine family", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 10 days" + }, + "crossTolerances": [ + "dopamine", + "serotonin|serotonergic", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 62, + "name": "3-FMC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/3-fmc", + "experiencesUrl": null, + "summary": "A stimulant drug related to mephedrone. A member of the cathinone class, it is also an amphetamine. Effects similar to other drugs of its class, may possess high addiction potential. May be a monoamine releaser, reuptake inhibitor or both.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-150mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Rapid." + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 63, + "name": "3-FPM", + "aliases": [ + "3-fph", + "3f-p", + "3f-phenmetrazine", + "3fp", + "3fpm", + "pal-593" + ], + "aliasesStr": "3-fph,3f-p,3f-phenmetrazine,3fp,3fpm,pal-593", + "url": "https://psychonautwiki.org/wiki/3-FPM", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_3FPhenmetrazine.shtml", + "summary": "A functional stimulant related to phenmetrazine. Effects similar to amphetamine, but longer and more focused. Observed as being relatively benign in low doses, but seems to cause worrying health effects for heavy users. Pain from insufflation is eye-wateringly intense, but short.", + "reagents": null, + "classes": { + "chemical": [ + "Phenylmorpholine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "30 - 90 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "5 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 64, + "name": "3-HO-PCE", + "aliases": [ + "3hopce", + "hydroxyeticyclidine" + ], + "aliasesStr": "3hopce,hydroxyeticyclidine", + "url": "https://psychonautwiki.org/wiki/3-HO-PCE", + "experiencesUrl": null, + "summary": "A rare and very potent PCP analogue, eight times more potent than PCP as NMDA receptor antagonist and also a μ-opioid receptor agonist. Similar in structure to methoxetamine.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a moderate potential for adverse side effects such as psychosis", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "4 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +", + "note": "Redosing may result in dangerous cumulative effects." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 65, + "name": "3-HO-PCP", + "aliases": [ + "3hopcp", + "hydroxyphencyclidine" + ], + "aliasesStr": "3hopcp,hydroxyphencyclidine", + "url": "https://psychonautwiki.org/wiki/3-HO-PCP", + "experiencesUrl": null, + "summary": "An arylcyclohexamine dissociative analogue of PCP, this drug is relatively uncommon, and little information is available. It is reported to not only have dissociative activity but also be an opioid. Some trip reports suggest very negative side-effects including intense muscle tension.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for adverse side effects such as psychosis", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "4 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 6 mg" + }, + { + "name": "Strong", + "value": "6 - 8 mg" + }, + { + "name": "Heavy", + "value": "8 mg +", + "note": "Redosing may result in dangerous cumulative effects." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Come up", + "value": "60 - 90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 66, + "name": "3-MEC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/3-mec", + "experiencesUrl": null, + "summary": "Another cathinone based stimulant, that is weaker than 4-MEC. Very few reports since it is quite unpopular.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-175mg" + }, + { + "name": "Strong", + "value": "175-250mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "2-5 hours" + } + ] + }, + { + "name": "Insufflated:", + "dosage": [ + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-150mg+" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Duration", + "value": "1-1.5 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 67, + "name": "3-MeO-PCE", + "aliases": [ + "3meopce", + "methoxyeticyclidine", + "methoxyieticyclidine" + ], + "aliasesStr": "3meopce,methoxyeticyclidine,methoxyieticyclidine", + "url": "https://psychonautwiki.org/wiki/3-MeO-PCE", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_3MEOPCE_.shtml", + "summary": "3-MeO-PCP with a change of a ring replacement. Slightly more potent than 3-MeO-PCP.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociatives" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25+ mg", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "3 - 15 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "45 - 60 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 68, + "name": "3-MeO-PCMO", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/3-meo-pcmo", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_3MeOPCMo.shtml", + "summary": "A less common dissociative anaesthetic compound related to PCP. An analogue of 3-meo-pcp, but far less potent. Possibly an antitussive and antidepressant. Very little history of human use or pharmacological information.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-80mg" + }, + { + "name": "Common", + "value": "80-125mg" + }, + { + "name": "Strong", + "value": "125-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "2-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 69, + "name": "3-MeO-PCP", + "aliases": [ + "3-meo", + "3meopcp" + ], + "aliasesStr": "3-meo,3meopcp", + "url": "https://psychonautwiki.org/wiki/3-MeO-PCP", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_3MeOPCP.shtml", + "summary": "A potent dissociative often compared to MXE but with a longer duration, much less sedating effects and causing an overall different experience. Users have reported effects as being similar to PCP. Roughtly ten times more potent than 4-MeO-PCP.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "produces dependence with chronic use and has a high potential for abuse", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "45 - 120 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "45 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "45 - 60 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "IM", + "duration": [ + { + "name": "Onset", + "value": "3-7 minutes" + }, + { + "name": "After effects", + "value": "2-48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 70, + "name": "3-MeO-PCPR", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/3-meo-pcpr", + "experiencesUrl": null, + "summary": "This is the N-Propyl homologue of 3-MeO-PCE. It is slightly less potent than PCP. Yet seems slightly less manic inducing.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-8mg" + }, + { + "name": "Common", + "value": "8-15mg" + }, + { + "name": "Strong", + "value": "15-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-8mg" + }, + { + "name": "Strong", + "value": "8-15mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 71, + "name": "3-MeO-PCPY", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/3-meo-pcpy", + "experiencesUrl": null, + "summary": "3-Methoxy analogue of Rolicyclidine (PCPy) less opioid effects than Phenylcyclidine (PCP) Yet still prominent.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2-4mg" + }, + { + "name": "Common", + "value": "4-8mg" + }, + { + "name": "Strong", + "value": "8-15mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-6mg" + }, + { + "name": "Strong", + "value": "6-10mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 72, + "name": "3-MeOMC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/3-meomc", + "experiencesUrl": null, + "summary": "A cathinone that has a short history of human use.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "5-7 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 73, + "name": "3-MMC", + "aliases": [ + "3-meph", + "3-mephedrone", + "3-methylmethcathinone", + "3methylmethcathinone", + "3mmc", + "metaphedrone" + ], + "aliasesStr": "3-meph,3-mephedrone,3-methylmethcathinone,3methylmethcathinone,3mmc,metaphedrone", + "url": "https://psychonautwiki.org/wiki/3-MMC", + "experiencesUrl": null, + "summary": "A euphoric stimulant similar to mephedrone but said to lack much of the \"magic.\" Never gained the same popularity. Slightly less potent.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "50 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 350 mg" + }, + { + "name": "Heavy", + "value": "350 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 120 mg" + }, + { + "name": "Heavy", + "value": "120 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 4.5 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "10 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 1.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 1.5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 74, + "name": "3-OH-PHENAZEPAM", + "aliases": [ + "3-ho-p", + "3-ho-phenazepam", + "3-hydroxyphenazepam", + "3-oh-p", + "3hop", + "3hophenazepam", + "3ohp", + "3ohphenazepam" + ], + "aliasesStr": "3-ho-p,3-ho-phenazepam,3-hydroxyphenazepam,3-oh-p,3hop,3hophenazepam,3ohp,3ohphenazepam", + "url": "https://drugs.tripsit.me/3-oh-phenazepam", + "experiencesUrl": null, + "summary": "The 3-OH analogue of Phenazepam, which cuts the half life down quite a bit. Psychoactive effects are mostly lead by its metabolites, rather than the drug itself.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Heavy", + "value": "2-4mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "10-24 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 75, + "name": "3C-E", + "aliases": [ + "3c-escaline" + ], + "aliasesStr": "3c-escaline", + "url": "https://psychonautwiki.org/wiki/3C-E", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_3CE.shtml", + "summary": "Three-Carbon Analog of Escaline. Substituted Amphetamine.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "30 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 16 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "3 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 7 hours" + }, + { + "name": "Offset", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "3 - 5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 76, + "name": "3C-P", + "aliases": [ + "3cp" + ], + "aliasesStr": "3cp", + "url": "https://drugs.tripsit.me/3c-p", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_3CP.shtml", + "summary": "Rather new and uncommon stimulant, psychedelic and amphetamine with properties similar to the 2Cx class of drugs. 3-carbon homologue of proscaline.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5-10mg" + }, + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Heavy", + "value": "40+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-150 minutes" + }, + { + "name": "Duration", + "value": "10-18 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 77, + "name": "4,4-DMAR", + "aliases": [ + "4,4-dmap", + "serotoni" + ], + "aliasesStr": "4,4-dmap,serotoni", + "url": "https://drugs.tripsit.me/4,4-dmar", + "experiencesUrl": null, + "summary": "Very closely related stimulant to Aminorex and Pemoline. Was sold as a designer drug for quite awhile under the brand name \"Serotoni\" has been linked to at least 31 deaths. It is a potent SNDRA.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "30-60mg" + }, + { + "name": "Common", + "value": "60-120mg" + }, + { + "name": "Strong", + "value": "120-200mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 78, + "name": "4-AcO-DALT", + "aliases": [ + "4acodalt" + ], + "aliasesStr": "4acodalt", + "url": "https://drugs.tripsit.me/4-aco-dalt", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4AcODALT.shtml", + "summary": "An uncommon tryptamine derivative first reported in the mid 2000s, likely a psychedelic. Little is known about the pharmacology or effects of this compound.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20mg" + }, + { + "name": "Light", + "value": "40-50mg" + }, + { + "name": "Common", + "value": "50-70mg" + }, + { + "name": "Heavy", + "value": "100+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "5-9 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Vaporized", + "dosage": [ + { + "name": "Threshold", + "value": "2-4mg" + }, + { + "name": "Light", + "value": "5-8mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "5-9 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 79, + "name": "4-AcO-DET", + "aliases": [ + "4-acetoxy-det", + "ethacetin", + "ethylacybin" + ], + "aliasesStr": "4-acetoxy-det,ethacetin,ethylacybin", + "url": "https://psychonautwiki.org/wiki/4-AcO-DET", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4AcODET.shtml", + "summary": "Rare drug that is of the tryptamine family, can be comparable to Psilocybin. Expected to quickly hydrolyzed into the free phenolic 4-HO-DET.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 1.5 hours" + }, + { + "name": "Peak", + "value": "1.5 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 80, + "name": "4-AcO-DiPT", + "aliases": [ + "4-acetoxy-dipt", + "4acodipt", + "aces", + "ipracetin", + "iprocetyl" + ], + "aliasesStr": "4-acetoxy-dipt,4acodipt,aces,ipracetin,iprocetyl", + "url": "https://psychonautwiki.org/wiki/4-AcO-DiPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4AcODiPT.shtml", + "summary": "An uncommon psychedelic tryptamine with a short history of human use, also known as Ipracetin. Possibly first synthesised by Alexander Shulgin. Some reports of heavy nausea, with effects comparable to 2c-b and mushrooms.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 81, + "name": "4-AcO-DMT", + "aliases": [ + "4-acetoxy-dmt", + "4-aco", + "4acodmt", + "o-acetylpsilocin", + "psilacetin", + "synthetic mushrooms" + ], + "aliasesStr": "4-acetoxy-dmt,4-aco,4acodmt,o-acetylpsilocin,psilacetin,synthetic mushrooms", + "url": "https://psychonautwiki.org/wiki/4-AcO-DMT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4AcODMT.shtml", + "summary": "A prodrug for Psilocin with extremely similar effects as Mushrooms.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with low potential for abuse", + "tolerance": { + "full": "almost immediately after ingestion", + "half": null, + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "7.5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 75 minutes" + }, + { + "name": "Peak", + "value": "2 - 3.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 25 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 hours - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 82, + "name": "4-AcO-DPT", + "aliases": [ + "4acodpt" + ], + "aliasesStr": "4acodpt", + "url": "https://drugs.tripsit.me/4-aco-dpt", + "experiencesUrl": null, + "summary": "Research chemical of the Tryptamine class. First noted being sold in 2012, yet never recieved much attention. Conflicting reports. Doesn't dissolve well at all in nearly all solutions it was tested in.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-15mg" + }, + { + "name": "Common", + "value": "15-25mg" + }, + { + "name": "Strong", + "value": "25-35mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "Insufflated minutes" + }, + { + "name": "After effects", + "value": "2-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 83, + "name": "4-AcO-MET", + "aliases": [ + "4-acetoxy-met", + "4acomet", + "metacetin", + "o-acetylmetocin" + ], + "aliasesStr": "4-acetoxy-met,4acomet,metacetin,o-acetylmetocin", + "url": "https://psychonautwiki.org/wiki/4-AcO-MET", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4AcOMET.shtml", + "summary": "A rare psychedelic tryptamine which is thought to be metabolised into 4-HO-MET. Onset and duration, intensity will vary but effect profile is largely the same.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 84, + "name": "4-AcO-MiPT", + "aliases": [ + "4acomipt", + "mipracetin", + "o-acetylmiprocin" + ], + "aliasesStr": "4acomipt,mipracetin,o-acetylmiprocin", + "url": "https://psychonautwiki.org/wiki/4-AcO-MiPT", + "experiencesUrl": null, + "summary": "A quite potent tryptamine that has be related to having \"shroom-like\" visuals. Yet without much bodyload. Very hydroscopic. Seems to be quite safe in dosing. Similar to the likes of 2C-B.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "1.5 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + } + ] + }, + { + "name": "Duration", + "duration": [ + { + "name": "Duration", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 85, + "name": "4-Benzylpiperidine", + "aliases": [ + "4-pmpd" + ], + "aliasesStr": "4-pmpd", + "url": "https://drugs.tripsit.me/4-benzylpiperidine", + "experiencesUrl": null, + "summary": "A dopamine releasing agent with weak serotonin releasing properties. Little evidence of human use. Potentially dangerous in overdose given MAOI + monoamine releasing properties.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "75-125mg" + }, + { + "name": "Common", + "value": "125-200mg" + }, + { + "name": "Strong", + "value": "200-350mg" + }, + { + "name": "Heavy", + "value": "350mg+." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 86, + "name": "4-CBC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-cbc", + "experiencesUrl": null, + "summary": "Is a potentially very neurotoxic Cathinone. Obviously no scientic reports have been noted on the neurotoxicity or cardiotoxicity, so please move on with extreme caution.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "40-70mg" + }, + { + "name": "Common", + "value": "70-100mg" + }, + { + "name": "Strong", + "value": "100-130mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60mg minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "2-6 hours" + } + ] + }, + { + "name": "Insufflated:", + "dosage": [ + { + "name": "Common", + "value": "50-80mg" + }, + { + "name": "Strong", + "value": "80-100mg." + } + ], + "duration": [ + { + "name": "After effects", + "value": "2-6 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "2-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 87, + "name": "4-CHLORODIAZEPAM", + "aliases": [ + "4'-chlorodiazepam", + "ro5-4864" + ], + "aliasesStr": "4'-chlorodiazepam,ro5-4864", + "url": "https://drugs.tripsit.me/4-chlorodiazepam", + "experiencesUrl": null, + "summary": "A benzodiazepine derivative of Diazepam, yet lacks affinity for GABA(a) receptors, yet is still a sedative, that has pro-convulsant effects. Yet at lower doses it has been proven to be neuroprotective.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 88, + "name": "4-CIC", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-cic", + "experiencesUrl": null, + "summary": "Inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 89, + "name": "4-CMA", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-cma", + "experiencesUrl": null, + "summary": "The stimulant that is the N-Methyl Derivative and prodrug of the neurotoxic para-Chloroamphetamine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 90, + "name": "4-CMC", + "aliases": [ + "4cmc" + ], + "aliasesStr": "4cmc", + "url": "https://drugs.tripsit.me/4-cmc", + "experiencesUrl": null, + "summary": "(Note this work is going off just a few users inputs, so take all of this with a grain of salt) The cathinone analogue of 4-CMA which is highly neurotoxic. It is not known if the cathinone family holds the same neurotoxicity problem as with the parent compound.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20-30mg" + }, + { + "name": "Light", + "value": "30-50mg" + }, + { + "name": "Common", + "value": "50mg-100mg" + }, + { + "name": "Strong", + "value": "100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "Few hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 91, + "name": "4-EMC", + "aliases": [ + "4-ethylmethcathinone" + ], + "aliasesStr": "4-ethylmethcathinone", + "url": "https://drugs.tripsit.me/4-emc", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4Ethylmethcathinone.shtml", + "summary": "A stimulant that is a structural isomer of 4-MEC.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-200mg" + }, + { + "name": "Strong", + "value": "200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "2-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 92, + "name": "4-EPD", + "aliases": [ + "4-ethylpentedrone" + ], + "aliasesStr": "4-ethylpentedrone", + "url": "https://drugs.tripsit.me/4-epd", + "experiencesUrl": null, + "summary": "An obscure analogue of Pentedrone, which means very little information on this chemical. It is likely is shares the same general effects of the other Pentedrone family.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-30mg" + }, + { + "name": "Strong", + "value": "30-50mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 93, + "name": "4-FA", + "aliases": [ + "4-fluoroamphetamine", + "4-fmp", + "4fa", + "flux", + "pal-303" + ], + "aliasesStr": "4-fluoroamphetamine,4-fmp,4fa,flux,pal-303", + "url": "https://psychonautwiki.org/wiki/4-FA", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4Fluoroamphetamine.shtml", + "summary": "An empathogen commonly used in place of MDMA, having a similar duration of empathogenic effects. This drug, however, has a longer stimulant \"tail,\" during which effects are more like those of amphetamines. Not to be confused with 4-FMA, which has a similar potency, but is not particularly empathogenic.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulants" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "40 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 130 mg" + }, + { + "name": "Strong", + "value": "130 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + }, + { + "name": "Come up", + "value": "30 - 75 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 3.5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 94, + "name": "4-FEA", + "aliases": [ + "4-fluoroethylamphetamine" + ], + "aliasesStr": "4-fluoroethylamphetamine", + "url": "https://drugs.tripsit.me/4-fea", + "experiencesUrl": null, + "summary": "Stimulant that is the ethyl analogue of 4-FMA.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-75mg" + }, + { + "name": "Strong", + "value": "75-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "40-60 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 95, + "name": "4-Fluoroethylphenidate", + "aliases": [ + "4-feph", + "4f-eph" + ], + "aliasesStr": "4-feph,4f-eph", + "url": "https://drugs.tripsit.me/4-fluoroethylphenidate", + "experiencesUrl": null, + "summary": "A more potent and longer lasting analogue of Ethylphenidate.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-30mg" + }, + { + "name": "Strong", + "value": "30-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-25 minutes" + }, + { + "name": "Duration", + "value": "5-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 96, + "name": "4-Fluoromethylphenidate", + "aliases": [ + "4-fl-mph", + "4-fluoro-mph", + "4-fmph", + "4f-mph", + "4fmph" + ], + "aliasesStr": "4-fl-mph,4-fluoro-mph,4-fmph,4f-mph,4fmph", + "url": "https://drugs.tripsit.me/4-fluoromethylphenidate", + "experiencesUrl": null, + "summary": "A relatively uncommon, more serotonergic RC derivative of methylphenidate. A dopamine reuptake inhibitor possessing similar effects to associated stimulant compounds.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1-5mg" + }, + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15-20mg" + }, + { + "name": "Heavy", + "value": "20-25mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "25-40 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "5-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 97, + "name": "4-Fluoropentedrone", + "aliases": [ + "4-f-pentedrone", + "4-fpd", + "4f-pentedrone" + ], + "aliasesStr": "4-f-pentedrone,4-fpd,4f-pentedrone", + "url": "https://drugs.tripsit.me/4-fluoropentedrone", + "experiencesUrl": null, + "summary": "An obscure analogue of pentedrone, little information exists about this cathinone. It is likely that it has the same general effects as pentedrone, mephedrone and other related stimulants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 98, + "name": "4-FMA", + "aliases": [ + "4-fluromethamphetamine", + "4fma" + ], + "aliasesStr": "4-fluromethamphetamine,4fma", + "url": "https://psychonautwiki.org/wiki/4-FMA", + "experiencesUrl": null, + "summary": "A stimulant with some empathogenic properties, and analogue of Methamphetamine with similar effects. Reported to be less effective than 2-FMA and related compounds. Little is known about the pharmacological effects of this compound. Not to be confused with 4-FA, which has a different effect profile, despite similar potency.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 75 mg" + }, + { + "name": "Strong", + "value": "100 - 125 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "3 - 12 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 99, + "name": "4-FMC", + "aliases": [ + "4-fluoromethcathinone", + "4fmc", + "flephedrone", + "fpephedrone" + ], + "aliasesStr": "4-fluoromethcathinone,4fmc,flephedrone,fpephedrone", + "url": "https://drugs.tripsit.me/4-fmc", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4Fluoromethcathinone.shtml", + "summary": "A cathinone stimulant also known as flephedrone, appeared in 2008 marketed as a mephedrone replacement. With some mild empathogenic effects, it failed to achieve widespread popularity.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "150-200+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "25-40mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-150+mg" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 100, + "name": "4-FPM", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-fpm", + "experiencesUrl": null, + "summary": "Seems to be a substance, that was just made to get money. High doses needed to feel any effects. Would avoid.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "60-90 minutes" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 101, + "name": "4-FPP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-fpp", + "experiencesUrl": null, + "summary": "A piperazine derivative that has been reported to have mild pyschedelic effects, and also empathogen qualities. It has been sold in many branded legal highs.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-80mg" + }, + { + "name": "Strong", + "value": "80-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 102, + "name": "4-HO-DET", + "aliases": [ + "4-hydroxy-det", + "4hodet", + "cz-74", + "ethocin" + ], + "aliasesStr": "4-hydroxy-det,4hodet,cz-74,ethocin", + "url": "https://psychonautwiki.org/wiki/4-HO-DET", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4HODET.shtml", + "summary": "A rare compound first produced by Albert Hoffman, also known as ethocin. Structurally related to 4-HO-MET (metocin) and psilocin (4-HO-DMT), this drug has similar psychedelic effects but little recorded human usage. Probably similar to mushrooms. Potentially stimulating.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 3.5 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 103, + "name": "4-HO-DiPT", + "aliases": [ + "iprocin" + ], + "aliasesStr": "iprocin", + "url": "https://psychonautwiki.org/wiki/4-HO-DiPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4HODiPT.shtml", + "summary": "A psychedelic tryptamine also known as iprocin. A homologue of psilocin, this drug likely has similar effects to psychedelic mushrooms. Said to have a rapid onset and relatively short duration for a drug of its class.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "3 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 104, + "name": "4-HO-DPT", + "aliases": [ + "4-hydroxy-n", + "4hodpt", + "n-dipropyltryptamine", + "procin" + ], + "aliasesStr": "4-hydroxy-n,4hodpt,n-dipropyltryptamine,procin", + "url": "https://psychonautwiki.org/wiki/4-HO-DPT", + "experiencesUrl": null, + "summary": "A psychedelic hallucinogenic first synthesized by alexander shulgin. At light doses it causes enhanced cognition and appreciation for things like art and music while high doses cause visuals. The drug is known to cause a bodyload.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 90 mg" + }, + { + "name": "Strong", + "value": "90 - 130 mg" + }, + { + "name": "Heavy", + "value": "130 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 60 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 45 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 105, + "name": "4-HO-EPT", + "aliases": [ + "eprocin" + ], + "aliasesStr": "eprocin", + "url": "https://psychonautwiki.org/wiki/4-HO-EPT", + "experiencesUrl": null, + "summary": "The 4-Hydroxy version of EPT. Slightly more potent than the prior.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "25 - 50 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 106, + "name": "4-HO-MCPT", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-ho-mcpt", + "experiencesUrl": null, + "summary": "Novel synthetic tryptamine that is the cyclopropyl homologue of Psilocin. Not much is known about anything.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 107, + "name": "4-HO-MET", + "aliases": [ + "4homet", + "colour", + "ethocin", + "homet", + "methylcybin", + "metocin" + ], + "aliasesStr": "4homet,colour,ethocin,homet,methylcybin,metocin", + "url": "https://psychonautwiki.org/wiki/4-HO-MET", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4HOMET.shtml", + "summary": "A lesser known psychedelic tryptamine. Functional analogue of Psilocin. Very poorly soluble in water and alcohol.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "25 - 45 minutes" + }, + { + "name": "Onset", + "value": "15 - 120 seconds" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Light", + "value": "5mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "2-10 minutes" + }, + { + "name": "Duration", + "value": "3-7 hours" + }, + { + "name": "After effects", + "value": "2-8 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-25 minutes" + }, + { + "name": "Duration", + "value": "3-7 hours" + }, + { + "name": "After effects", + "value": "2-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 108, + "name": "4-HO-MiPT", + "aliases": [ + "4-ho", + "4homipt", + "ho-mipt", + "homipt", + "miprocin" + ], + "aliasesStr": "4-ho,4homipt,ho-mipt,homipt,miprocin", + "url": "https://psychonautwiki.org/wiki/4-HO-MiPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4HOMiPT.shtml", + "summary": "A reasonably popular tryptamine deriviative and Psilocin analogue, first synthesised by Alexander Shulgin. It has been reported as having comparable effects to psychedelic mushrooms, though with a shorter duration.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 109, + "name": "4-HO-MPMI", + "aliases": [ + "lucigenol" + ], + "aliasesStr": "lucigenol", + "url": "https://drugs.tripsit.me/4-ho-mpmi", + "experiencesUrl": null, + "summary": "A rare tryptamine derivative first synthesised by David Nichols. This drug, also known as lucigenol, has rarely been documented outside the lab. It is known to be a psychedelic similar to other psychoactive tryptamines, with a potency similar to DOI, but little else is known.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "500-750ug." + }, + { + "name": "Light", + "value": "750ug-1mg" + }, + { + "name": "Common", + "value": "1-2mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-60 minutes" + }, + { + "name": "Duration", + "value": "6-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 110, + "name": "4-HO-MPT", + "aliases": [ + "4hompt", + "meprocin" + ], + "aliasesStr": "4hompt,meprocin", + "url": "https://psychonautwiki.org/wiki/4-HO-MPT", + "experiencesUrl": null, + "summary": "Psychedelic drug of the tryptamine class. Higher homologue of Psilocin, and is the 4-hydroxy analogue of N-Methyl-N-Propyltryptamine.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "3-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "45-90 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 111, + "name": "4-MEC", + "aliases": [ + "4-methylethcathinone", + "4mec" + ], + "aliasesStr": "4-methylethcathinone,4mec", + "url": "https://drugs.tripsit.me/4-mec", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4Methylethcathinone.shtml", + "summary": "A substituted cathinone stimulant; little is known about its safety or subjective effects. It is believed to have similar effects to mephedrone, but with a lower potency and a stronger stimulating character.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-200mg" + }, + { + "name": "Strong", + "value": "200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "25-40mg" + }, + { + "name": "Common", + "value": "40-100mg" + }, + { + "name": "Strong", + "value": "100-150mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 112, + "name": "4-MeO-Butyrfentanyl", + "aliases": [ + "4-meo-bf" + ], + "aliasesStr": "4-meo-bf", + "url": "https://drugs.tripsit.me/4-meo-butryfentanyl", + "experiencesUrl": null, + "summary": "Rare and basically unknown opioid and fentanyl analogue (not to be confused with Butyrfentanyl). Virtually no reliable information exists, safe dosages are unknown. Exercise extreme caution. Overdose may result in respiratory depression. Do not mix with stimulants or depressants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "45-120 minutes" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "30-75 minutes" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 113, + "name": "4-MeO-MiPT", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-meo-mipt", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4MeOMiPT.shtml", + "summary": "A rare psychedelic tryptamine first synthesised by Alexander Shulgin, said to the be \"little brother\" of 5-MeO-MiPT. Said to be relatively mild with lighter visual effects than most tryptamines.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "3-7 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 114, + "name": "4-MeO-PCP", + "aliases": [ + "4meopcp", + "methoxydine" + ], + "aliasesStr": "4meopcp,methoxydine", + "url": "https://psychonautwiki.org/wiki/4-MeO-PCP", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4MeOPCP.shtml", + "summary": "An arylcyclohexamine dissociative anaesthetic related to PCP. First discovered in the 1960s by Parke-Davis, it was introduced to the RC market in 2008. Reported to be less potent than PCP. It is not commonly seen, but has seen some increase in popularity with the inavailability of other dissociatives.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "75 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 170 mg" + }, + { + "name": "Strong", + "value": "170 - 250 mg" + }, + { + "name": "Heavy", + "value": "250 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 20 hours" + }, + { + "name": "Onset", + "value": "45 - 120 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 7 hours" + }, + { + "name": "Offset", + "value": "6 - 10 hours" + }, + { + "name": "After effects", + "value": "6+ hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "30 - 75 mg" + }, + { + "name": "Common", + "value": "75 - 150 mg" + }, + { + "name": "Strong", + "value": "150mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 18 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "3 - 6 hours" + }, + { + "name": "Offset", + "value": "3 hours" + }, + { + "name": "After effects", + "value": "3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 115, + "name": "4-METHYLAMINOREX", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-methylaminorex", + "experiencesUrl": null, + "summary": "A very potent stimulant that has quite a long duration of action at around 16 hours.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1mg" + }, + { + "name": "Light", + "value": "1-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "14-18 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 116, + "name": "4-Methylmethylphenidate", + "aliases": [ + "4-me-tmp", + "4-metmp", + "4-mmph" + ], + "aliasesStr": "4-me-tmp,4-metmp,4-mmph", + "url": "https://drugs.tripsit.me/4-methylmethylphenidate", + "experiencesUrl": null, + "summary": "A stimulant drug related to methylphenidate and also known as 4-Me-TMP, it has demonstrated lower dopamine reuptake inhibition properties and is potentially less potent. Has been subjectively described as very similar in feel to MPH.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-40mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60-90mg" + }, + { + "name": "Heavy", + "value": "90-125mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-35 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-45mg" + }, + { + "name": "Strong", + "value": "45-70mg" + }, + { + "name": "Heavy", + "value": "70mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 117, + "name": "4-MPD", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4-mpd", + "experiencesUrl": null, + "summary": "Stimulant of the cathinone class. Higher homologue of Mephedrone, and the p-Methyl analogue of Pentedrone.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 118, + "name": "4-MTA", + "aliases": [ + "4-methylthioamphetamine" + ], + "aliasesStr": "4-methylthioamphetamine", + "url": "https://drugs.tripsit.me/4-mta", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4MTA.shtml", + "summary": "Empathogen with very low chronic toxicity but high risk of acute harm due to mixed serotonin release and MAOI action. Reported to lack euphoria and rarely sold since being scheduled.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 119, + "name": "4F-EPH", + "aliases": [ + "4feph" + ], + "aliasesStr": "4feph", + "url": "https://psychonautwiki.org/wiki/4F-EPH", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 25 minutes" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 120, + "name": "4F-MPH", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/4F-MPH", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "5 - 10 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 14 mg" + }, + { + "name": "Strong", + "value": "14 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 121, + "name": "4F-NEB", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4f-neb", + "experiencesUrl": null, + "summary": "The 4-Fluoro analogue of N-Ethylbuphedrone (NEB) is a part of the cathinone class.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "75-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "150-300mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "90-180 minutes" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "50-75" + }, + { + "name": "Common", + "value": "75-150mg" + }, + { + "name": "Strong", + "value": "150-250mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "50-100 minutes" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 122, + "name": "4F-PHP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/4f-php", + "experiencesUrl": null, + "summary": "4-Fluoro analogue of a-PHP, yet seems to have less mania attachted to it. Dose is near on par.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Insufflated minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 123, + "name": "4F-PVP", + "aliases": [ + "4f-a-pvp", + "pfpvp" + ], + "aliasesStr": "4f-a-pvp,pfpvp", + "url": "https://drugs.tripsit.me/4f-pvp", + "experiencesUrl": null, + "summary": "Fluornated analogue of a-PVP. Seems to be slightly less weaker than it's parent compound.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-25mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-20 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 124, + "name": "5-APB", + "aliases": [ + "5apb" + ], + "aliasesStr": "5apb", + "url": "https://psychonautwiki.org/wiki/5-APB", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5APB.shtml", + "summary": "A triple monoamine reuptake inhibitor. This agonism for 5-HT2B makes it likely that 5-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 125, + "name": "5-APDB", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-apdb", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5APDB.shtml", + "summary": "An entactogenic amphetamine stimulant with similar structure and effects to MDMA. An analogue of MDA, it is a highly selective serotonin releaser but inhibits reuptake of serotonin (weakly), dopamine and norepinephrine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-75mg" + }, + { + "name": "Common", + "value": "75-125mg" + }, + { + "name": "Heavy", + "value": "125-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 126, + "name": "5-APDI", + "aliases": [ + "iap" + ], + "aliasesStr": "iap", + "url": "https://drugs.tripsit.me/5-apdi", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_IAP.shtml", + "summary": "Also commonly known as IAP. A selective serotonin releasing agent with psychedelic and empathogenic properties. Users have often reported issues with the drug causing overheating and unwelcome bowel movements.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "15-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50-75mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "8-14 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 127, + "name": "5-BPDI", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-bpdi", + "experiencesUrl": null, + "summary": "An analogue of a-PHP, which has been described as having an extremely similar effect profile, with some users noting that it may be slightly lighter and with less of an urge to redose. However, little record of the safety of human use exists.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "7.5-10mg" + }, + { + "name": "Common", + "value": "10-25mg" + }, + { + "name": "Strong", + "value": "25-45mg" + }, + { + "name": "Heavy", + "value": "45+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "3-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 128, + "name": "5-Bromo-DMT", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-br-dmt", + "experiencesUrl": null, + "summary": "Psychedelic drug of the Trypyamine class, and is also found in two marine invertebrates. Animal studies have shown that this could be useful for sedative and/or antidepressant use.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "10-25mg." + }, + { + "name": "Common", + "value": "25-35mg." + }, + { + "name": "Strong", + "value": "35-65mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "15-90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 129, + "name": "5-DBFPV", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-dbfpv", + "experiencesUrl": null, + "summary": "Stimulant of the cathinone class. Analogue of MDPV where the methylenedioxyphenyl group was replaced with a dihydrobenzofuran.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2-5mg" + }, + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-60mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "After effects", + "value": "4-12 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "After effects", + "value": "4-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 130, + "name": "5-EAPB", + "aliases": [ + "5eapb" + ], + "aliasesStr": "5eapb", + "url": "https://drugs.tripsit.me/5-eapb", + "experiencesUrl": null, + "summary": "A empathogen sold as a replacement to 5-MAPB after it was banned in the UK, but said to be less enjoyable and never gained much popularity.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-60mg" + }, + { + "name": "Common", + "value": "60-100mg" + }, + { + "name": "Strong", + "value": "100-150+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Oral minutes" + }, + { + "name": "Duration", + "value": "5-6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "30-40mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60-100+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Oral minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 131, + "name": "5-HTP", + "aliases": [ + "5-hydroxytryptophan", + "5htp", + "and triptum", + "cincofarm", + "l-tryptophan", + "levothym", + "levotonine", + "oxitriptan", + "oxyfan", + "telesol", + "tript-oh", + "tryptophan" + ], + "aliasesStr": "5-hydroxytryptophan,5htp,and triptum,cincofarm,l-tryptophan,levothym,levotonine,oxitriptan,oxyfan,telesol,tript-oh,tryptophan", + "url": "https://psychonautwiki.org/wiki/5-Hydroxytryptophan", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Tryptophan.shtml", + "summary": "The precursor to serotonin. In some countries it is sold OTC as a supplement for mood stabilisation and insomnia. It is frequently used as a recovery supplement following the use of MDMA or any other drug that depletes serotonin. Do not mix this drug with anything serotonergic, as this can cause serotonin syndrome.", + "reagents": null, + "classes": { + "chemical": [ + "Amino_acid", + "Substituted_tryptamines" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 300 mg" + }, + { + "name": "Strong", + "value": "300 - 500 mg" + }, + { + "name": "Heavy", + "value": "500 mg +" + } + ], + "duration": null + }, + { + "name": "Therapeutic", + "dosage": [ + { + "name": "Common", + "value": "50-100mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + } + ] + }, + { + "name": "Sleep", + "dosage": [ + { + "name": "Common", + "value": "100-200mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + } + ] + }, + { + "name": "Recovery", + "dosage": [ + { + "name": "Common", + "value": "200-300mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 132, + "name": "5-IAI", + "aliases": [ + "5iai" + ], + "aliasesStr": "5iai", + "url": "https://drugs.tripsit.me/5-iai", + "experiencesUrl": null, + "summary": "A monoamine triple releaser first synthesised by David Nichols, possesses similar properties to MDMA. Probably neurotoxic in humans, however the extent of this is unclear.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 133, + "name": "5-IT", + "aliases": [ + "5-api" + ], + "aliasesStr": "5-api", + "url": "https://drugs.tripsit.me/5-it", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5IT.shtml", + "summary": "An empathogenic stimulant with a very long duration, prone to cause overheating and potentially quite dangerous. Related to αMT, though described as being less psychedelic and with much stronger stimulating effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "90-120 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "1-48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 134, + "name": "5-MAPB", + "aliases": [ + "5mapb" + ], + "aliasesStr": "5mapb", + "url": "https://psychonautwiki.org/wiki/5-MAPB", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MAPB.shtml", + "summary": "An empathogen structurally similar to MDMA. Typically more visual than MDMA. Often reported to be much less stimulating and more relaxing than most other stimulating empathogens. Less psychedelic than 6-APB. Much longer lasting than MDMA.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 135, + "name": "5-MAPDB", + "aliases": [ + "5mapdb" + ], + "aliasesStr": "5mapdb", + "url": "https://drugs.tripsit.me/5-mapdb", + "experiencesUrl": null, + "summary": "An entactogenic drug with similar effects to MDMA, it is related to 5-MAPB. Likely to release serotonin and show neurotoxicity in the same way as MDMA", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-75mg" + }, + { + "name": "Common", + "value": "75-120mg" + }, + { + "name": "Strong", + "value": "120-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-70 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 136, + "name": "5-MeO-αMT", + "aliases": [ + "5meoamt" + ], + "aliasesStr": "5meoamt", + "url": "https://drugs.tripsit.me/5-meo-amt", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeOAMT.shtml", + "summary": "A long-acting psychedelic and entactogenic tryptamine, related to aMT. Very potent and may be sold on blotters. Possibly has been missold as LSD in the past, however this is uncommon. Possibly an MAOI.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5-1mg" + }, + { + "name": "Light", + "value": "1-2mg" + }, + { + "name": "Common", + "value": "2-4mg" + }, + { + "name": "Strong", + "value": "4-6mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "12-18 hours" + }, + { + "name": "After effects", + "value": "4-24+ hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "4-24+ hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 137, + "name": "5-MeO-DALT", + "aliases": [ + "5meodalt", + "foxtrot" + ], + "aliasesStr": "5meodalt,foxtrot", + "url": "https://psychonautwiki.org/wiki/5-MeO-DALT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeODALT.shtml", + "summary": "A strange drug with an unknown mechanism of action. Some psychedelic effects alongside some effects non-characteristic of psychedelics like appetite enhancement. Reported as having rapid, intense and short acting entheogenic effects.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 20 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "Peak", + "value": "1 - 5 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "5 - 10 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "5 - 12 mg" + }, + { + "name": "Common", + "value": "12 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + } + ] + }, + { + "name": "Vaporized", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-15mg" + }, + { + "name": "Strong", + "value": "15+mg" + } + ] + } + ], + "interactions": null + }, + { + "id": 138, + "name": "5-MeO-DiBF", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/5-MeO-DiBF", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeODiBF.shtml", + "summary": "An uncommon and new psychedelic drug related to tryptamine; the Benzofuran analogue of 5-MeO-DiPT. Probably a serotonin receptor partial agonist. Little history of human use.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_benzofurans" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "50 - 80 mg" + }, + { + "name": "Common", + "value": "80 - 110 mg" + }, + { + "name": "Strong", + "value": "110 - 140 mg" + }, + { + "name": "Heavy", + "value": "140 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-45 minutes" + }, + { + "name": "Duration", + "value": "6-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 139, + "name": "5-MeO-DiPT", + "aliases": [ + "5meodipt", + "foxy", + "foxy methoxy", + "foxy-methoxy" + ], + "aliasesStr": "5meodipt,foxy,foxy methoxy,foxy-methoxy", + "url": "https://psychonautwiki.org/wiki/5-MeO-DiPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeODiPT.shtml", + "summary": "5-methoxy-di isopropyl tryptamine, also known as 'foxy', a psychedelic tryptamine related to DMT, which distorts visual and audio perception. Reported to have a heavy body load at high doses, it behaves similarly to other drugs of its class.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "3 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 140, + "name": "5-MeO-DMT", + "aliases": [ + "5-medmt", + "5-meo", + "5meo", + "5meodmt", + "the god molecule", + "toads" + ], + "aliasesStr": "5-medmt,5-meo,5meo,5meodmt,the god molecule,toads", + "url": "https://psychonautwiki.org/wiki/5-MeO-DMT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeODMT.shtml", + "summary": "A powerful psychedelic tryptamine found in many species of plants and some toad venom, with a history of use by native South Americans spanning thousands of years. Has similar qualities to DMT and related tryptamines. Very potent. Orally active in combination with an MAOI.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 hour", + "zero": "2 hours" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "20 - 40 minutes" + }, + { + "name": "Onset", + "value": "5 - 60 seconds" + }, + { + "name": "Come up", + "value": "30 - 60 seconds" + }, + { + "name": "Peak", + "value": "5 - 15 minutes" + }, + { + "name": "Offset", + "value": "10 - 20 minutes" + }, + { + "name": "After effects", + "value": "15 - 60 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "1 - 10 minutes" + }, + { + "name": "Peak", + "value": "10 - 40 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 141, + "name": "5-MeO-DPT", + "aliases": [ + "5meodpt" + ], + "aliasesStr": "5meodpt", + "url": "https://drugs.tripsit.me/5-meo-dpt", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeODPT.shtml", + "summary": "A rare tryptamine psychedelic and analogue of DPT. Little is known about this compound but it is likely to have effects similar to DPT, DMT and others related compounds.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "3mg" + }, + { + "name": "Common", + "value": "3-5mg" + }, + { + "name": "Strong", + "value": "5-10mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 142, + "name": "5-MeO-EiPT", + "aliases": [ + "5meoeipt" + ], + "aliasesStr": "5meoeipt", + "url": "https://drugs.tripsit.me/5-meo-eipt", + "experiencesUrl": null, + "summary": "A little known and little studied tryptamine and analogue of EiPT, also related to DiPT and DET. Probably a psychedelic. Few reports of effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2-5mg" + }, + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-25mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1-3mg" + }, + { + "name": "Light", + "value": "3-7mg" + }, + { + "name": "Common", + "value": "7-15mg" + }, + { + "name": "Strong", + "value": "15-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-10 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 143, + "name": "5-MeO-MALT", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-meo-malt", + "experiencesUrl": null, + "summary": "A new and uncommon psychedelic tryptamine related to 5-MeO-DALT. Little is known about it, but its effects are probably similar to other psychedelic tryptamines.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "15-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-30 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15-20mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "0.5-1.5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 144, + "name": "5-MeO-MET", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-meo-met", + "experiencesUrl": null, + "summary": "An obscure psychedelic drug similar in structure to 5-MeO-DMT. Possibly first synthesised by Alexander Shulgin. Likely to have similar effects to other tryptamine psychedelics.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "13-15mg" + }, + { + "name": "Common", + "value": "15-25mg" + }, + { + "name": "Strong", + "value": "25mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "1-5mg" + }, + { + "name": "Common", + "value": "5-8mg" + }, + { + "name": "Strong", + "value": "8-12mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 145, + "name": "5-MeO-MiPT", + "aliases": [ + "5meo-mipt", + "5meomipt", + "moxy" + ], + "aliasesStr": "5meo-mipt,5meomipt,moxy", + "url": "https://psychonautwiki.org/wiki/5-MeO-MiPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeOMIPT.shtml", + "summary": "A potent, stimulating psychedelic tryptamine, sometimes compared to 5-MeO-DiPT. Has an unusually strong body component and weak visual effects. Often said to be very empathogenic.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics", + "Entactogens" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "3 - 7 mg" + }, + { + "name": "Common", + "value": "7 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 146, + "name": "5-MeO-NIPT", + "aliases": [ + "5meonipt" + ], + "aliasesStr": "5meonipt", + "url": "https://drugs.tripsit.me/5-meo-nipt", + "experiencesUrl": null, + "summary": "A little known and little studied tryptamine and analogue of NiPT, also related to DiPT and DET. Psychedelic, that is generally regarded as not worth the time.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2-4mg" + }, + { + "name": "Common", + "value": "8-15mg" + }, + { + "name": "Strong", + "value": "15-25mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 147, + "name": "5-MeO-PYR-T", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-meo-pyr-t", + "experiencesUrl": null, + "summary": "A very odd acting tryptamine, that is very potent. With doses as low as 3mg vapourised causing complete blocks of memory loss.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-1.5mg" + }, + { + "name": "Strong", + "value": "1.5-2mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "2-6 hours" + }, + { + "name": "After effects", + "value": "1-36 hours" + } + ] + }, + { + "name": "Vapourised", + "dosage": [ + { + "name": "Light", + "value": "0.5-1.5mg" + }, + { + "name": "Common", + "value": "1.5-2mg" + }, + { + "name": "Strong", + "value": "2-3mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "1-5 hours" + }, + { + "name": "After effects", + "value": "1-36 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 148, + "name": "5-Methylethylone", + "aliases": [ + "5-me", + "5-methyl-ethylone" + ], + "aliasesStr": "5-me,5-methyl-ethylone", + "url": "https://drugs.tripsit.me/5-methyl-bk-mdea", + "experiencesUrl": null, + "summary": "Also known as 5-methyl ethylone or 5-ME, this is a cathinone drug and analogue of ethylone. Little is known about this obscure compound but it is reasonable to assume it has an effect profile similar to other stimulants of the cathionone class, with a slightly higher potency than ethylone. Potentially entactogenic and a monoamine releasing agent.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-250mg" + }, + { + "name": "Strong", + "value": "250-400mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "30-60mg" + }, + { + "name": "Common", + "value": "60-150mg" + }, + { + "name": "Strong", + "value": "150-300mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "2-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 149, + "name": "5-PPDI", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5-ppdi", + "experiencesUrl": null, + "summary": "An obscure analogue of α-PBP, which is itself an analogue of α-PVP. This rare compound has little history of human usage. Some trip reports suggest it is inactive. If it is active it likely has a similar effect profile to other pyrovalerone stimulants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "15-30mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Strong", + "value": "50-70mg" + }, + { + "name": "Heavy", + "value": "70+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "3-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 150, + "name": "5F-AKB48", + "aliases": [ + "5f-apinaca", + "5fakb48", + "5fapinaca" + ], + "aliasesStr": "5f-apinaca,5fakb48,5fapinaca", + "url": "https://psychonautwiki.org/wiki/5F-AKB48", + "experiencesUrl": null, + "summary": "A synthetic cannabanoid that is a Indazole. Produces subjective effects somehwat similar to that of Cannabis, yet with a very short duration. Analogue of STS-135, in which the core indole structure is subbed with an indazole base.", + "reagents": null, + "classes": { + "chemical": [ + "Adamantanes", + "Indazolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "cannabinoids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0 - 20 minutes" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "15 - 30 minutes" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Threshold", + "value": "500ug" + }, + { + "name": "Light", + "value": "500-1000ug" + }, + { + "name": "Strong", + "value": "1000-2500ug." + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-30" + }, + { + "name": "Duration", + "value": "30-60 minutes" + }, + { + "name": "After effects", + "value": "15-45 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 151, + "name": "5F-PB-22", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/5f-pb-22", + "experiencesUrl": null, + "summary": "Synthetic cannabinoid, agonist of the cannabinoid receptors which has a strong sedating aspect. Being a synthetic cannabinoid it has a very fast onset.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "1mg" + }, + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-5mg" + }, + { + "name": "Strong", + "value": "5-8mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10" + }, + { + "name": "Duration", + "value": "60-90 minutes" + }, + { + "name": "After effects", + "value": "30-60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 152, + "name": "6-APB", + "aliases": [ + "6apb", + "benzofury" + ], + "aliasesStr": "6apb,benzofury", + "url": "https://psychonautwiki.org/wiki/6-APB", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_6APB.shtml", + "summary": "A stimulant, empathogen and analog of MDA. Typically more visual than MDMA or MDA, as well as having a much longer onset and duration. Users often report a slightly more psychedelic headspace as well. Commonly sold as an alternative to MDMA and MDA.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3-4 weeks", + "zero": "6-8 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "30 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 90 mg" + }, + { + "name": "Strong", + "value": "90 - 120 mg" + }, + { + "name": "Heavy", + "value": "120 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + }, + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "50-75mg" + }, + { + "name": "Common", + "value": "75-125mg" + }, + { + "name": "Heavy", + "value": "125mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "8-14 hours" + }, + { + "name": "After effects", + "value": "6-apb" + } + ] + } + ], + "interactions": null + }, + { + "id": 153, + "name": "6-APDB", + "aliases": [ + "4-desoxy-mda" + ], + "aliasesStr": "4-desoxy-mda", + "url": "https://psychonautwiki.org/wiki/6-APDB", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_6APDB.shtml", + "summary": "A stimulant and entactogen related to MDMA and an analogue of MDA. Reported as being fairly psychedlic at higher doses. It is a triple monoamine reuptake inhibitor. Potent full agonist of serotonin 2B receptors.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines", + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "21-30 days", + "zero": "2-3 months" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "30 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 130 mg" + }, + { + "name": "Heavy", + "value": "130 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 154, + "name": "6-EAPB", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/6-eapb", + "experiencesUrl": null, + "summary": "A rare entactogen benzofuran structurally related to MDMA and 6-APB, though weaker in effects. the pharmacology of this compound is unclear. Likely to be a monoamine releaser, monoamine reuptake inhibitor or both.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-75mg" + }, + { + "name": "Common", + "value": "75-100mg" + }, + { + "name": "Strong", + "value": "100-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "4-7 hours" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 155, + "name": "6-MAPB", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/6-mapb", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_6MAPB.shtml", + "summary": "Empathogen drug that is structurally related to 6-APB and MDMA.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-80mg" + }, + { + "name": "Strong", + "value": "80-100mg" + } + ], + "duration": [ + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Strong", + "value": "40-100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Within minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + }, + { + "name": "Orally", + "duration": [ + { + "name": "Onset", + "value": "Within minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 156, + "name": "6-MDDM", + "aliases": [ + "6-methylenedihydrodesoxymorphine" + ], + "aliasesStr": "6-methylenedihydrodesoxymorphine", + "url": "https://drugs.tripsit.me/6-mddm", + "experiencesUrl": null, + "summary": "Semisynthetic opioid that is a derivative of Hydromorphone with little history of human use. Roughly around ~80x the potency of Morphine. Structurally related to Desomorphine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "125ug" + }, + { + "name": "Common", + "value": "187-250ug" + }, + { + "name": "Strong", + "value": "375ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-15 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 157, + "name": "A-PHP", + "aliases": [ + "alpha-php", + "aphp", + "pv-7", + "pv7", + "α-php", + "αphp" + ], + "aliasesStr": "alpha-php,aphp,pv-7,pv7,α-php,αphp", + "url": "https://psychonautwiki.org/wiki/A-PHP", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_alphaPHP.shtml", + "summary": "A powerful stimulant cathinone, analogue of alpha-PVP and related to pyrovalerone. Said to have high addictive potential, compulsive redosing and relatively short duration. Often insufflated or vapourised.", + "reagents": null, + "classes": { + "chemical": [ + "Pyrrolidinophenone", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 8 minutes" + }, + { + "name": "Peak", + "value": "30 - 90 minutes" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 8 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 5 hours" + }, + { + "name": "After effects", + "value": "1 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "20 - 45 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 158, + "name": "A-PIHP", + "aliases": [ + "pihp" + ], + "aliasesStr": "pihp", + "url": "https://drugs.tripsit.me/a-pihp", + "experiencesUrl": null, + "summary": "Quite new Pyrrolidine based stimulant of the cathinone class. Not very many reports. Probably has a very fast tolerance raise, and lack of effects over time.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3-5mg" + }, + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-50mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "6-12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1-3mg" + }, + { + "name": "Light", + "value": "3-10mg" + }, + { + "name": "Common", + "value": "10-25mg" + }, + { + "name": "Strong", + "value": "25-40mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "6-12 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Threshold", + "value": "1-2mg" + }, + { + "name": "Light", + "value": "2-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-30mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "6-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 159, + "name": "A-PVP", + "aliases": [ + "alpha-pvp", + "alpha-pyrrolidinopentiophenone", + "apvp", + "flakka", + "flocka", + "o-2387", + "prolintanone", + "α-pvp", + "αpvp", + "β-ketone-prolintane" + ], + "aliasesStr": "alpha-pvp,alpha-pyrrolidinopentiophenone,apvp,flakka,flocka,o-2387,prolintanone,α-pvp,αpvp,β-ketone-prolintane", + "url": "https://psychonautwiki.org/wiki/A-PVP", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_aPVP.shtml", + "summary": "A potent, short-lasting pyrovalerone-type stimulant which became popular despite often being said to not be particularly euphoric, perhaps due to its propensity to cause compulsive redosing. Effects should be similar to MDPV.", + "reagents": null, + "classes": { + "chemical": [ + "Pyrrolidinophenone", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "20 - 60 seconds" + }, + { + "name": "Peak", + "value": "3 - 6 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 5 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "20 - 45 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 160, + "name": "α-PVT", + "aliases": [ + "apvt" + ], + "aliasesStr": "apvt", + "url": "https://drugs.tripsit.me/a-pvt", + "experiencesUrl": null, + "summary": "A rare stimulant drug related to a-PVP, very uncommon. Probably less potent than a-PVP, however little data exists on this compound or its effects on humans.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "1-10 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Vapourized", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 161, + "name": "AB-CHMINACA", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/ab-chminaca", + "experiencesUrl": null, + "summary": "A synthetic cannabinoid related to AB-FUBINACA which has had some mild popularity. There have been reports of death in overdose, similar to AB-FUBINACA and it has a low threshold dose. Exercise caution.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100µg" + }, + { + "name": "Common", + "value": "100-250µg" + }, + { + "name": "Strong", + "value": "250-400µg" + }, + { + "name": "Heavy", + "value": "400µg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-80 minutes" + }, + { + "name": "Duration", + "value": "5-12 hours" + }, + { + "name": "After effects", + "value": "5-12 hours" + } + ] + }, + { + "name": "Vaporized", + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 162, + "name": "AB-FUBINACA", + "aliases": [ + "ab-fub", + "ab-fubi" + ], + "aliasesStr": "ab-fub,ab-fubi", + "url": "https://psychonautwiki.org/wiki/AB-FUBINACA", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_ABFUBINACA.shtml", + "summary": "Arguably the most common synthetic cannabinoid, AB-FUBINACA was originally developed by Pfizer as an analgesic, but has since abandoned for medical use. It has since found a following in the RC community, however it's extremely high potency and inclusion in synthetic blends makes it dangerous, and it has killed in overdose. Exercise caution.", + "reagents": null, + "classes": { + "chemical": [ + "Indazolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "cannabinoids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 1 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "0 - 20 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "10 - 20 minutes" + }, + { + "name": "After effects", + "value": "15 - 30 minutes" + } + ] + }, + { + "name": "Vaporized", + "dosage": [ + { + "name": "Light", + "value": "0.25-0.5mg" + }, + { + "name": "Common", + "value": "0.5-1.5mg" + }, + { + "name": "Strong", + "value": "1.5-3mg" + }, + { + "name": "Heavy", + "value": "3+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.25-0.5mg" + }, + { + "name": "Common", + "value": "0.5-1.5mg" + }, + { + "name": "Strong", + "value": "1.5-3mg" + }, + { + "name": "Heavy", + "value": "3+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-240 minutes" + }, + { + "name": "Duration", + "value": "5-15 hours" + }, + { + "name": "After effects", + "value": "2-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 163, + "name": "Acetildenafil", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/acetildenafil", + "experiencesUrl": null, + "summary": "An RC analogue of sildenafil (viagra) often missold as a hidden ingredient in many 'natural' sexual potency blends and supplements.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-40mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "3-7 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 164, + "name": "Acetylfentanyl", + "aliases": [ + "a-f", + "acetyl-fentanyl" + ], + "aliasesStr": "a-f,acetyl-fentanyl", + "url": "https://psychonautwiki.org/wiki/Acetylfentanyl", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Acetylfentanyl.shtml", + "summary": "Acetyl-Fentanyl is an opioid analgesic substance that is an analogue of Fentanyl. It's potency is roughly ~6.67 times that of Morphine. Making it ~15 times less potent than its parent compound Fentanyl.", + "reagents": null, + "classes": { + "chemical": [ + "Anilidopiperidine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "unintentionally spilling a very small amount of acetylfentanyl on one's skin could result in a fatal overdose." + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + }, + { + "name": "Onset", + "value": "7 - 10 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-5mg" + }, + { + "name": "Strong", + "value": "5-7mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "1-4 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 165, + "name": "Acrylfentanyl", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/acryl-fentanyl", + "experiencesUrl": null, + "summary": "A rare opioid and fentanyl analogue (not to be confused with acetyl-fentanyl), this drug is a powerful and potent analgesic. Little reliable information exists, even for basic usage such as dosage. Exercise extreme caution. Overdose may result in respiratory depression. Do not mix with depressants or stimulants. Potentially neurotoxic and carcinogenic.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "5-12.5ug" + }, + { + "name": "Common", + "value": "12.5-25ug" + }, + { + "name": "Strong", + "value": "25.47.5ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 166, + "name": "Adderall", + "aliases": [ + "adderal", + "aderal", + "aderall", + "amphetamine", + "d-amph", + "d-amphetamine", + "pep", + "speed" + ], + "aliasesStr": "adderal,aderal,aderall,amphetamine,d-amph,d-amphetamine,pep,speed", + "url": "https://psychonautwiki.org/wiki/Amphetamine", + "experiencesUrl": null, + "summary": "A mixture of 75% dextroamphetamine and 25% levoamphetamine. Commonly used to treat obesity, narcolepsy and ADHD. It is also used widely either as a recreational stimulant or study-aid, particularly in the USA where it is frequently prescribed.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "has a high abuse potential and can cause dependence with chronic use", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "7.5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + }, + { + "name": "Come up", + "value": "30 - 135 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "3 - 6 hours" + } + ], + "bioavailability": "75%+" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "6 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1.5 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Oral-IR", + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Oral-XR", + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Insufflated-XR", + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Insufflated-IR", + "duration": [ + { + "name": "Onset", + "value": "0-10 minutes" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 167, + "name": "Adinazolam", + "aliases": [ + "deracyn" + ], + "aliasesStr": "deracyn", + "url": "https://drugs.tripsit.me/adinazolam", + "experiencesUrl": null, + "summary": "Benzodiazepine derivative that has some antidepressant properties. Never FDA approved, yet however has been sold as a research chemical.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-25 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 168, + "name": "Adrafinil", + "aliases": [ + "olmifon" + ], + "aliasesStr": "olmifon", + "url": "https://psychonautwiki.org/wiki/Adrafinil", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Adrafinil.shtml", + "summary": "A prodrug to modafinil, this compound is often used to increase wakefulness and alertness. Due to hepatic metabolism it has a slower onset than modafinil and may cause liver damage in excess. Some users have reported acne as an adverse effect. Unregulated in the US.", + "reagents": null, + "classes": { + "chemical": null, + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": null, + "addictionPotential": "not addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "benzhydryl", + "nootropic|nootropics" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100 mg" + }, + { + "name": "Light", + "value": "150 - 250 mg" + }, + { + "name": "Common", + "value": "250 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 600 mg" + }, + { + "name": "Heavy", + "value": "600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "45 - 60 minutes" + }, + { + "name": "Peak", + "value": "4.5 - 6 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ], + "bioavailability": "75-80%" + } + ], + "interactions": null + }, + { + "id": 169, + "name": "αET", + "aliases": [ + "a-et", + "a-ethyltryptamine", + "alpha-ethyl-tryptamine" + ], + "aliasesStr": "a-et,a-ethyltryptamine,alpha-ethyl-tryptamine", + "url": "https://drugs.tripsit.me/aet", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_AET.shtml", + "summary": "A quite rare substance of the tryptamine class, was first made by Upjohn as an antidepressant. Please use extreme caution if you get the pleasure of trying this drug.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "80-100mg" + }, + { + "name": "Common", + "value": "100-125mg" + }, + { + "name": "Strong", + "value": "125-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-120 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 170, + "name": "Afloqualone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/afloqualone", + "experiencesUrl": null, + "summary": "A rare analogue of methaqualone, a sedative, intoxicating drug. Similar effects to benzodiazepines, barbiturates and alcohol. Never widely used due to photosensitivity and skin irritation issues, though it has seem some popularity in Japan.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "75-100mg" + }, + { + "name": "Strong", + "value": "100-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 171, + "name": "AH-7921", + "aliases": [ + "ah7921" + ], + "aliasesStr": "ah7921", + "url": "https://drugs.tripsit.me/ah-7921", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_AH7921.shtml", + "summary": "Opioid analgesic that is selective for the μ-opioid receptor. It has around 80% the potency of Morphine when taken orally.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-25mg" + }, + { + "name": "Strong", + "value": "25mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "6-8 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Vaporized", + "duration": [ + { + "name": "Onset", + "value": "2-10 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 172, + "name": "AL-LAD", + "aliases": [ + "aladdin", + "allad" + ], + "aliasesStr": "aladdin,allad", + "url": "https://psychonautwiki.org/wiki/AL-LAD", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_ALLAD.shtml", + "summary": "AL-LAD is a hallucinogenic drug, lysergamide and an analogue of LSD. It is reported as having some subtle experiential differences to LSD (such as increased visuals), and also appears to be slightly shorter lasting. AL-LAD doses are similar to those of LSD, depending on purity. Its availability on the Internet since 2013 has lead to strong popularity among the drug community.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown", + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 µg" + }, + { + "name": "Light", + "value": "50 - 100 µg" + }, + { + "name": "Common", + "value": "100 - 225 µg" + }, + { + "name": "Strong", + "value": "225 - 350 µg" + }, + { + "name": "Heavy", + "value": "350 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 18 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 173, + "name": "Alcohol", + "aliases": [ + "beer", + "booze", + "ethanol", + "etoh", + "hooch" + ], + "aliasesStr": "beer,booze,ethanol,etoh,hooch", + "url": "https://drugs.tripsit.me/alcohol", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Alcohol.shtml", + "summary": "Alcohol is a CNS depressant that acts through the GABAₐ receptor, and is one of the most common strong psychoactives used by humans. It has a long history of use and its intoxicating effects are well-studied and documented. It remains legal in most parts of the world.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "1-2units" + }, + { + "name": "Common", + "value": "2-4units" + }, + { + "name": "Heavy", + "value": "5-6units" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "1.5-3 hours" + }, + { + "name": "After effects", + "value": "6-48 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Low Risk & Decrease", + "note": "Both these classes of compound can interact unpredictably. Caution should be exercised.", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Decrease", + "name": "2C-x" + }, + { + "status": "Low Risk & Decrease", + "name": "5-MeO-xxT" + }, + { + "status": "Caution", + "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol and the stimulant less. Extended release formulations may severely impede sleep, further worsening the hangover.", + "name": "Amphetamines" + }, + { + "status": "Dangerous", + "note": "Ethanol ingestion may potentiate the CNS effects of many benzodiazepines. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Blacking out and memory loss is almost certain.", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "note": "In excess, this combination can cause nausea.", + "name": "Cannabis" + }, + { + "status": "Unsafe", + "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol less. Cocaine is potentiated somewhat by alcohol because of the formation of cocaethylene.", + "name": "Cocaine" + }, + { + "status": "Low Risk & Decrease", + "name": "DMT" + }, + { + "status": "Low Risk & Decrease", + "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk.", + "name": "DOx" + }, + { + "status": "Dangerous", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Additionally CNS depression can lead to difficulty breathing. Avoid on anything higher than 1st plateau.", + "name": "DXM" + }, + { + "status": "Dangerous", + "note": "Even in very low doses this combination rapidly leads to memory loss, severe ataxia and unconsciousness. There is a high risk of vomit aspiration while unconscious.", + "name": "GHB/GBL" + }, + { + "status": "Dangerous", + "note": "Both substances cause ataxia and bring a very high risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.", + "name": "Ketamine" + }, + { + "status": "Low Risk & Decrease", + "name": "LSD" + }, + { + "status": "Unsafe", + "note": "Tyramine found in many alcoholic beverages can have dangerous reactions with MAOIs, causing an increase in blood pressure.", + "name": "MAOIs" + }, + { + "status": "Caution", + "note": "Both MDMA and alcohol cause dehydration. Approach this combination with caution, moderation and sufficient hydration. More than a small amount of alcohol will dull the euphoria of MDMA", + "name": "MDMA" + }, + { + "status": "Dangerous", + "note": "There is a high risk of memory loss, vomiting and severe ataxia from this combination.", + "name": "MXE" + }, + { + "status": "Low Risk & Decrease", + "name": "Mescaline" + }, + { + "status": "Low Risk & Decrease", + "name": "Mushrooms" + }, + { + "status": "Low Risk & Decrease", + "name": "NBOMes" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.", + "name": "Nitrous" + }, + { + "status": "Dangerous", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely", + "name": "Opioids" + }, + { + "status": "Unsafe", + "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.", + "name": "PCP" + }, + { + "status": "Caution", + "note": "Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "note": "Heavy CNS depressants, risk of seizures. Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely.", + "name": "Tramadol" + }, + { + "status": "Caution", + "note": "aMT has a broad mechanism of action in the brain and so does alcohol so the combination can be unpredictable", + "name": "aMT" + } + ] + }, + { + "id": 174, + "name": "ALD-52", + "aliases": [ + "1-acetyl-lsd", + "1a-lad", + "1a-lsd", + "1alsd", + "ald52", + "orange sunshine" + ], + "aliasesStr": "1-acetyl-lsd,1a-lad,1a-lsd,1alsd,ald52,orange sunshine", + "url": "https://psychonautwiki.org/wiki/ALD-52", + "experiencesUrl": null, + "summary": "ALD-52, or N-acetyl-LSD is a less common chemical analogue of LSD, first synthesised by Albert Hoffman. It was famously implicated in the 'Orange Sunshine' trial. A psychedelic lysergamide, this compound exhibits similar properties to LSD, and is thought to be a pro-drug for LSD.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown", + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 µg" + }, + { + "name": "Light", + "value": "30 - 100 µg" + }, + { + "name": "Common", + "value": "100 - 175 µg" + }, + { + "name": "Strong", + "value": "175 - 325 µg" + }, + { + "name": "Heavy", + "value": "325 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 175, + "name": "Aleph", + "aliases": [ + "dot", + "para-dot" + ], + "aliasesStr": "dot,para-dot", + "url": "https://drugs.tripsit.me/aleph", + "experiencesUrl": null, + "summary": "The first sulphur-containing Phenethylamine to have been evaluated for CNS activity for Stimulant or Psychedelic purposes.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2-4mg" + }, + { + "name": "Common", + "value": "4-6mg" + }, + { + "name": "Strong", + "value": "6-12mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 176, + "name": "ALEPH-2", + "aliases": [ + "aleph2", + "dot-2", + "dot2" + ], + "aliasesStr": "aleph2,dot-2,dot2", + "url": "https://drugs.tripsit.me/aleph-2", + "experiencesUrl": null, + "summary": "A very rare Phenethylamine, also known as DOT-2, it is the DOx analogue of 2C-T-2. Very little human use recorded. Described as being quite long and highly visual. Likely to be potent, with a reported threshold dose of 3mg.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 177, + "name": "Allobarbital", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/allobarbital", + "experiencesUrl": null, + "summary": "Is a barbiturate that was first made in 1912. It was primilary used as an anticonvulsant. Yet it has pretty much been outclassed by a newer generation of safer ones. Still in use in Poland.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "500-1000mg" + }, + { + "name": "Common", + "value": "1000-1500mg" + }, + { + "name": "Strong", + "value": "1500-2000mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 178, + "name": "Allylescaline", + "aliases": [ + "al" + ], + "aliasesStr": "al", + "url": "https://psychonautwiki.org/wiki/Allylescaline", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Allylescaline.shtml", + "summary": "Mescaline analogue with a much lower dose, that seems to rely heavily on colours.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "45 - 240 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 179, + "name": "Alpha-GPC", + "aliases": [ + "choline alfoscerate", + "l-alpha glycerylphosphorylcholine" + ], + "aliasesStr": "choline alfoscerate,l-alpha glycerylphosphorylcholine", + "url": "https://psychonautwiki.org/wiki/Alpha-GPC", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Choline_derivative" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "7 days", + "zero": "14 days" + }, + "crossTolerances": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 300 mg" + }, + { + "name": "Common", + "value": "300 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 1000 mg" + }, + { + "name": "Heavy", + "value": "1000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 180, + "name": "Alprazolam", + "aliases": [ + "ksalol", + "niravam", + "prazolam", + "xanax" + ], + "aliasesStr": "ksalol,niravam,prazolam,xanax", + "url": "https://psychonautwiki.org/wiki/Alprazolam", + "experiencesUrl": null, + "summary": "An extremely common benzodiazepine better known as Xanax, frequently prescribed for the treatment of anxiety and panic disorders. Alprazolam is short-lasting and primarily anxiolytic, though also possesses hypnotic properties. At high doses amnesia and loss of inhibition are common. Do not mix with other depressants.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7-14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Strong", + "value": "1.5 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 - 3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "2 - 6 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ], + "bioavailability": "80-90%" + } + ], + "interactions": null + }, + { + "id": 181, + "name": "AM-2201", + "aliases": [ + "am2201" + ], + "aliasesStr": "am2201", + "url": "https://drugs.tripsit.me/am-2201", + "experiencesUrl": null, + "summary": "A synthetic cannabanoid that is very potent. Active doses start at around 250ug's. Please be cautious with this substance. It has also been noted that it can cause convulsions.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "250-500ug" + }, + { + "name": "Common", + "value": "500-1000ug" + }, + { + "name": "Strong", + "value": "1000-2000ug" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-3 minutes" + }, + { + "name": "Duration", + "value": "30-90 minutes" + }, + { + "name": "After effects", + "value": "15-60 minutes" + } + ] + }, + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "60-180 minutes" + }, + { + "name": "After effects", + "value": "15-60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 182, + "name": "Amanita muscaria", + "aliases": [ + "fly agaric", + "fly amanita" + ], + "aliasesStr": "fly agaric,fly amanita", + "url": "https://psychonautwiki.org/wiki/Amanita_muscaria", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 183, + "name": "Amfecloral", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/amfecloral", + "experiencesUrl": null, + "summary": "Is a stimulant drug of the Phenethylamine and Amphetamine class. It was used as an appetite suppressant, yet is no longer marketed. It's also interesting that it acts as a prodrug to both Amphetamine and Chloral Hydrate.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 184, + "name": "Amfonelic acid", + "aliases": [ + "aa", + "afa", + "win25978" + ], + "aliasesStr": "aa,afa,win25978", + "url": "https://drugs.tripsit.me/amfonelicacid", + "experiencesUrl": null, + "summary": "A dopaminergic stimulant discovered by Sterling-Winthrop accidentally while developing antibiotics. Discontinued due to undesirable stimulant effects, it has had some popularity as a recreational drug.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2-4mg" + }, + { + "name": "Common", + "value": "4-10mg" + }, + { + "name": "Strong", + "value": "10mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 185, + "name": "Aminorex", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/aminorex", + "experiencesUrl": null, + "summary": "Is an anorectic stimulant drug that was taken of the market after it was found to cause pulmonary hypertension. Potency wise it has been found to be roughly 2.5 times more potent than dextroamphetamine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "none", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-10mg" + }, + { + "name": "Strong", + "value": "10-25mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 186, + "name": "Aminotadalafil", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/aminotadalafil", + "experiencesUrl": null, + "summary": "An analogue of tadafinil, better known as Cialis (Viagra). Infamous for being missold in the 'Alpha Male' sexual enhancement supplement.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-30mg" + } + ], + "duration": [ + { + "name": "Duration", + "value": "4-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 187, + "name": "Amobarbital", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/amobarbital", + "experiencesUrl": null, + "summary": "A sedative and hypnotic barbiturate first discovered in 1923. Formerly widely used recreationally and medically, barbiturates have declined in popularity with the appearance of benzodiazepines and other drugs with less serious consequences in overdose.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "50-75mg" + }, + { + "name": "Strong", + "value": "75-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "5-9 hours" + }, + { + "name": "After effects", + "value": "2-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 188, + "name": "Amphetamine", + "aliases": [ + "amfetamine", + "amph", + "amphetamin", + "amphetamines", + "hearts", + "pep", + "pepp", + "speed" + ], + "aliasesStr": "amfetamine,amph,amphetamin,amphetamines,hearts,pep,pepp,speed", + "url": "https://drugs.tripsit.me/amphetamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Amphetamines.shtml", + "summary": "A very popular CNS stimulant available on prescription and black markets. Recreational in high doses, producing mild euphoria and an abundance of energy. Popular in eastern europe and the US.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "15-25mg" + }, + { + "name": "Common", + "value": "25-40mg" + }, + { + "name": "Strong", + "value": "40-75mg" + }, + { + "name": "Heavy", + "value": "75-100mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-50mg" + }, + { + "name": "Strong", + "value": "50-70mg" + }, + { + "name": "Heavy", + "value": "70-90mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 189, + "name": "ΑMT", + "aliases": [ + "alpha-methyltryptamine", + "alphamethyltryptamine", + "amt", + "indopan", + "monase" + ], + "aliasesStr": "alpha-methyltryptamine,alphamethyltryptamine,amt,indopan,monase", + "url": "https://psychonautwiki.org/wiki/%CE%91MT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_AMT.shtml", + "summary": "A long-acting psychedelic-empathogen with a broad method of action in the brain. Not suitable for combination with many other substances. Used as an anti-depressant in the Soviet Union, but later found popularity in the RC scene, mainly in the UK.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics", + "Entactogens" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "moderately habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "14 days", + "zero": "1 month" + }, + "crossTolerances": [ + "psychedelics" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 - 80 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "13 - 15 hours" + }, + { + "name": "Onset", + "value": "60 - 180 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "1 - 5 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Dangerous", + "name": "2C-T-x" + }, + { + "status": "Dangerous", + "name": "2C-x" + }, + { + "status": "Dangerous", + "name": "5-MeO-xxT" + }, + { + "status": "Caution", + "note": "aMT has a broad mechanism of action in the brain and so does alcohol so the combination can be unpredictable", + "name": "Alcohol" + }, + { + "status": "Dangerous", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Caution", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.", + "name": "Caffeine" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Small amounts can reduce nausea with aMT but take care.", + "name": "Cannabis" + }, + { + "status": "Dangerous", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Dangerous", + "name": "DOx" + }, + { + "status": "Dangerous", + "name": "DXM" + }, + { + "status": "Low Risk & Decrease", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Dangerous", + "note": "aMT is an MAOI on its own. Using enzyme inhibitors can greatly reduce predictability of effects.", + "name": "MAOIs" + }, + { + "status": "Dangerous", + "name": "MDMA" + }, + { + "status": "Dangerous", + "name": "MXE" + }, + { + "status": "Dangerous", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Dangerous", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & No Synergy", + "note": "No unexpected interactions", + "name": "Opioids" + }, + { + "status": "Dangerous", + "name": "PCP" + }, + { + "status": "Dangerous", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "name": "Tramadol" + } + ] + }, + { + "id": 190, + "name": "Anadenanthera peregrina", + "aliases": [ + "cohoba", + "jopo", + "yopo" + ], + "aliasesStr": "cohoba,jopo,yopo", + "url": "https://psychonautwiki.org/wiki/Anadenanthera_peregrina", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 191, + "name": "Aniracetam", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Aniracetam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Aniracetam.shtml", + "summary": "An anxiolytic nootropic which modulates the AMPA receptor. Significantly more potent than racetam. May have positive effects on memory and cognition. Little recreational value. Sold in Europe as a prescription drug, but not approved by the FDA in the US.", + "reagents": null, + "classes": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": null, + "addictionPotential": "non-addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "racetam", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "350 mg" + }, + { + "name": "Light", + "value": "500 - 1200 mg" + }, + { + "name": "Common", + "value": "1200 - 1800 mg" + }, + { + "name": "Strong", + "value": "1800 - 2400 mg" + }, + { + "name": "Heavy", + "value": "2400 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "45 - 90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 192, + "name": "Paracetamol", + "aliases": [ + "acetaminophen", + "tylenol" + ], + "aliasesStr": "acetaminophen,tylenol", + "url": "https://drugs.tripsit.me/apap", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Acetaminophen.shtml", + "summary": "A common, over the counter, fever reducer and painkiller. It is mixed with many common opiates. Can cause liver damage and failure in higher doses. No recreational value.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Pain-relief", + "dosage": [ + { + "name": "Common", + "value": "200-400mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-60 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Fever", + "dosage": [ + { + "name": "Common", + "value": "300-500mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-60 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 193, + "name": "APICA", + "aliases": [ + "2ne1", + "sdb-001" + ], + "aliasesStr": "2ne1,sdb-001", + "url": "https://psychonautwiki.org/wiki/APICA", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Indole_cannabinoid", + "Indolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "cannabinoids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Common", + "value": "1.5 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0 - 20 seconds" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "15 - 35 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 194, + "name": "Armodafinil", + "aliases": [ + "artvigil", + "neoresotyl", + "nuvigil", + "r-modawake", + "waklert" + ], + "aliasesStr": "artvigil,neoresotyl,nuvigil,r-modawake,waklert", + "url": "https://psychonautwiki.org/wiki/Armodafinil", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Armodafinil.shtml", + "summary": "The more potent of the two modafinil isomers, said to have a longer duration and lesser side effects. Sometimes prescribed for ADHD and daytime sleepiness.", + "reagents": null, + "classes": { + "chemical": [ + "Benzhydryl" + ], + "psychoactive": [ + "Eugeroic" + ] + }, + "toxicity": [ + "The median lethal dose at which 50% of participants die (LD50) from either armodafinil or modafinil for human beings has never been reached" + ], + "addictionPotential": "mildly addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "benzhydryl", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 15 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "1 - 2.5 hours" + }, + { + "name": "Peak", + "value": "4 - 7 hours" + }, + { + "name": "Offset", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ], + "bioavailability": "97.78%" + } + ], + "interactions": null + }, + { + "id": 195, + "name": "Ashwagandha", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/ashwagandha", + "experiencesUrl": null, + "summary": "Is an Adaptogen. It is commonly used for its ability to prevent anxiety. It also is helpful in relieving insomnia. It's name means \"Smell of Horse\" due to its smell and the traditional belief that ingesting the this herb will give you the strength and virility of a horse.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "300-500" + }, + { + "name": "Common", + "value": "500-1000" + }, + { + "name": "Strong", + "value": "1000-2000" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-60 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 196, + "name": "Aspirin", + "aliases": [ + "acetylsalicylate" + ], + "aliasesStr": "acetylsalicylate", + "url": "https://drugs.tripsit.me/aspirin", + "experiencesUrl": null, + "summary": "A widely used anti-inflammatory and blood-thinner produced by acetylation of the naturally occurring salicyclic acid. Part of the nonsteroidal antiinflammatory class of drugs, a cyclooxygenase inhibitor. Very common over-the-counter pain reliever and fever reducer. Also used in smaller doses to lower risk of heart attack.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50mg" + }, + { + "name": "Light", + "value": "75mg-81mg" + }, + { + "name": "Common", + "value": "325mg-650mg" + }, + { + "name": "Heavy", + "value": "1.6g" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "Dose-Dependent" + } + ], + "bioavailability": "55.8-74%" + } + ], + "interactions": null + }, + { + "id": 197, + "name": "Atomoxetine", + "aliases": [ + "strattera" + ], + "aliasesStr": "strattera", + "url": "https://drugs.tripsit.me/atomoxetine", + "experiencesUrl": null, + "summary": "A NRI that is used for ADHD. With a quite odd pharmacological background.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-18mg" + }, + { + "name": "Common", + "value": "18-40mg" + }, + { + "name": "Strong", + "value": "40-80mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ], + "bioavailability": "63-94%" + } + ], + "interactions": null + }, + { + "id": 198, + "name": "Atropa belladonna", + "aliases": [ + "belladonna", + "deadly nightshade" + ], + "aliasesStr": "belladonna,deadly nightshade", + "url": "https://psychonautwiki.org/wiki/Atropa_belladonna", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tropanes" + ], + "psychoactive": [ + "Deliriant" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 199, + "name": "Ayahuasca", + "aliases": [ + "aya", + "caapi", + "cipó", + "hoasca", + "natem", + "pharmahuasca", + "shori", + "vegetal", + "yage", + "yagé", + "yajé" + ], + "aliasesStr": "aya,caapi,cipó,hoasca,natem,pharmahuasca,shori,vegetal,yage,yagé,yajé", + "url": "https://psychonautwiki.org/wiki/Ayahuasca", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ayahuasca.shtml", + "summary": "A concoction made of two or more plants that contain at least an MAOI and DMT, the combination of which allows the DMT to work orally. Typically associated to south american cultures. Also, sometimes approximated synthetically by taking an external MAOI with extracted DMT. Causes intense, spiritually orientated hallucinogenic experiences.", + "reagents": null, + "classes": { + "chemical": null, + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "LD50 is around 50 times a regular dose" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 200, + "name": "Baclofen", + "aliases": [ + "gablofen" + ], + "aliasesStr": "gablofen", + "url": "https://drugs.tripsit.me/baclofen", + "experiencesUrl": null, + "summary": "Also known as Lioresal, Baclofen is a GABAb receptor agonist and central nervous system depressant used to treat spasticity, and holds promise as a treatment for alcoholism. It exhibits mild intoxicating effects similar to phenibut or pregabalin.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-50" + }, + { + "name": "Strong", + "value": "50-75" + }, + { + "name": "Heavy", + "value": "75-125mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ], + "bioavailability": "74%" + } + ], + "interactions": null + }, + { + "id": 201, + "name": "Banisteriopsis caapi", + "aliases": [ + "ayahuasca", + "caapi or yagé" + ], + "aliasesStr": "ayahuasca,caapi or yagé", + "url": "https://psychonautwiki.org/wiki/Banisteriopsis_caapi", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 202, + "name": "Barbital", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/barbital", + "experiencesUrl": null, + "summary": "The first commercially available barbiturate. Was used commonly as a sleeping aid until the 1950s.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "650-970mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 203, + "name": "Bentazepam", + "aliases": [ + "thiadipone", + "tiadipona" + ], + "aliasesStr": "thiadipone,tiadipona", + "url": "https://drugs.tripsit.me/bentazepam", + "experiencesUrl": null, + "summary": "Thienodiazepine that is an effective anxiolyric. Liver damage among other nasty things have been reported.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "15-30mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Strong", + "value": "50-75mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 204, + "name": "BENZODIOXOLE-FENTANYL", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/benzodioxole-fentanyl", + "experiencesUrl": null, + "summary": "An analogue of Fentanyl that is not found in literature.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 205, + "name": "Benzydamine", + "aliases": [ + "tantum" + ], + "aliasesStr": "tantum", + "url": "https://drugs.tripsit.me/benzydamine", + "experiencesUrl": null, + "summary": "NSAID with local anesthetic and analgesic properties, similar to ibuprofen or naproxen. Sometimes abused in overdose with reported delirant and stimulant effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "250-500mg" + }, + { + "name": "Common", + "value": "500-1000mg" + }, + { + "name": "Strong", + "value": "1000-1500mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-60 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "2-48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 206, + "name": "Βk-2C-B", + "aliases": [ + "b-k-2-c-b", + "b-k-2cb", + "b-k2-c-b", + "b-k2-cb", + "b-k2cb", + "beta-keto 2c-b", + "bk-2-cb", + "bk-2c-b", + "bk-2cb", + "bk2cb" + ], + "aliasesStr": "b-k-2-c-b,b-k-2cb,b-k2-c-b,b-k2-cb,b-k2cb,beta-keto 2c-b,bk-2-cb,bk-2c-b,bk-2cb,bk2cb", + "url": "https://psychonautwiki.org/wiki/%CE%92k-2C-B", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_BK2CB.shtml", + "summary": "A long-acting psychedelic and empathogen with unpredictable effectiveness. Roughly double the duration of 2c-b. Inactivated by high pH.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "60 - 80 mg" + }, + { + "name": "Common", + "value": "80 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 70 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 207, + "name": "βk-2C-I", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/bk-2c-i", + "experiencesUrl": null, + "summary": "Novel psychedelic that is the Beta-Ketone derivative of 2C-I.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "100-120mg" + }, + { + "name": "Common", + "value": "120-180mg" + }, + { + "name": "Strong", + "value": "180-250mg" + }, + { + "name": "Heavy", + "value": "250mg+" + } + ] + } + ], + "interactions": null + }, + { + "id": 208, + "name": "βk-IVP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/bk-ivp", + "experiencesUrl": null, + "summary": "The beta-ketone analogue of IVP, this is a rare RC stimulant in the same family as MDPV. Little is known but effects are probably similar to MDPV or more generally amphetamine or high dose caffeine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "60-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "150-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Rapid." + }, + { + "name": "Duration", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 209, + "name": "BOD", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/bod", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_BOD.shtml", + "summary": "Beta-methoxy analogue of 2C-D, seems to be more \"mild\" than the likes of 2C-X and DOX compounds. Is 50/50 whether the body load is barely there, or overpowering the experience.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "12-15mg" + }, + { + "name": "Light", + "value": "15-20mg" + }, + { + "name": "Common", + "value": "20-30mg" + }, + { + "name": "Heavy", + "value": "30-40mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-120 minutes" + }, + { + "name": "Duration", + "value": "8-14 hours" + }, + { + "name": "After effects", + "value": "3-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 210, + "name": "Bromadol", + "aliases": [ + "bdpc" + ], + "aliasesStr": "bdpc", + "url": "https://drugs.tripsit.me/bromadol", + "experiencesUrl": null, + "summary": "A very potent opioid that has an arylcyclohexylamine structure. Intial studies estimated that it was ~10,000x Morphine in animal studies. However that value has since decreased to ~504 times the potency of morphine for the trans-isomer.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + } + ] + }, + { + "name": "Intramuscular", + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + }, + { + "name": "Intravenous", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 211, + "name": "Bromantane", + "aliases": [ + "bromantan", + "ladasten" + ], + "aliasesStr": "bromantan,ladasten", + "url": "https://psychonautwiki.org/wiki/Bromantane", + "experiencesUrl": null, + "summary": "An unusual stimulant and anxiolytic drug with dopamine and serotonin reuptake inhibition properties. Infamously used as a doping agent in the 1996 Olympics. There are some concerns it may exacerbate the underlying causes of Alzheimer's disease.", + "reagents": null, + "classes": { + "chemical": [ + "Adamantanes" + ], + "psychoactive": null + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "10 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + } + ], + "bioavailability": "42%" + } + ], + "interactions": null + }, + { + "id": 212, + "name": "Bromazepam", + "aliases": [ + "brazepam", + "lectopam", + "lexilium", + "lexotan", + "lexotanil" + ], + "aliasesStr": "brazepam,lectopam,lexilium,lexotan,lexotanil", + "url": "https://drugs.tripsit.me/bromazepam", + "experiencesUrl": null, + "summary": "A benzodiazepine drug with a medium-long duration, developed by Roche in the 1960s. Has primarily anxiolytic properties. May cause lowered inhibitions and amnesia in high doses.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Heavy", + "value": "10-15mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ], + "bioavailability": "84%" + } + ], + "interactions": null + }, + { + "id": 213, + "name": "Bromazolam", + "aliases": [ + "xli-268", + "xli268" + ], + "aliasesStr": "xli-268,xli268", + "url": "https://drugs.tripsit.me/bromazolam", + "experiencesUrl": null, + "summary": "A rather novel Benzodiazepine that is structurally quite close to Alprazolam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 214, + "name": "Bromo-DragonFLY", + "aliases": [ + "b-dfly", + "bdfly", + "bromo-d-fly", + "bromo-dragon-fly", + "dob-dragonfly", + "dragonfly" + ], + "aliasesStr": "b-dfly,bdfly,bromo-d-fly,bromo-dragon-fly,dob-dragonfly,dragonfly", + "url": "https://psychonautwiki.org/wiki/Bromo-DragonFLY", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_BromoDragonfly.shtml", + "summary": "A psychedelic phenethylamine and benzofuran that is very potent and has a long duration. Was briefly sold as \"2C-B-FLY\" in 2005/6 and has lead to multiple deaths.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_benzofurans", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "extreme vasoconstrictive effects", + "one can easily overdose if this substance is not measured correctly", + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "6 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 µg" + }, + { + "name": "Light", + "value": "100 - 300 µg" + }, + { + "name": "Common", + "value": "300 - 500 µg" + }, + { + "name": "Strong", + "value": "500 - 750 µg" + }, + { + "name": "Heavy", + "value": "750 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 days" + }, + { + "name": "Onset", + "value": "2 - 7 hours" + }, + { + "name": "Come up", + "value": "3 - 6 hours" + }, + { + "name": "Peak", + "value": "6 - 12 hours" + }, + { + "name": "Offset", + "value": "3 - 8 hours" + }, + { + "name": "After effects", + "value": "12 - 36 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 215, + "name": "Brotizolam", + "aliases": [ + "lendormin" + ], + "aliasesStr": "lendormin", + "url": "https://drugs.tripsit.me/brotizolam", + "experiencesUrl": null, + "summary": "Benzodiazepine analogue which is sedating, hypnotic and anxiolytic. It is available as prescription medicine in much of Europe, and is an extremely potent drug active at only 80ug. May cause amnesia and lowered inhibitions in overdose. Danger of respiratory depression when combined with other depressants. Short half life.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "80ug" + }, + { + "name": "Light", + "value": "100ug-200ug" + }, + { + "name": "Common", + "value": "200-400ug" + }, + { + "name": "Strong", + "value": "400ug-600ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 216, + "name": "Bufotenin", + "aliases": [ + "5-ho-dmt" + ], + "aliasesStr": "5-ho-dmt", + "url": "https://psychonautwiki.org/wiki/Bufotenin", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "1 hour", + "zero": "2 hours" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 90 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "Peak", + "value": "1 - 5 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "10 - 60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 217, + "name": "Buphedrone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/buphedrone", + "experiencesUrl": null, + "summary": "A cathinone stimulant first discovered in 1928, has gained some modest popularity as a mephedrone replacement. Said to be to be around 2-3x more potent than methcathinone.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-30mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Heavy", + "value": "50-80mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 218, + "name": "Buprenorphine", + "aliases": [ + "addnok", + "bupe", + "buprenex", + "butrans", + "cizdol", + "suboxone", + "subs", + "subutex", + "transtec" + ], + "aliasesStr": "addnok,bupe,buprenex,butrans,cizdol,suboxone,subs,subutex,transtec", + "url": "https://psychonautwiki.org/wiki/Buprenorphine", + "experiencesUrl": null, + "summary": "A semi-synthetic opioid analgesic also known as subutex. Often administered as Butrans patches, or in combination with Naloxone as Suboxone, a heroin replacement therapy drug. Will cause withdrawals if you have an opioid tolerance and don't wait long enough (typically around 48 hours) before taking this.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "<0.3 mg" + }, + { + "name": "Light", + "value": "0.3 - 0.6 mg" + }, + { + "name": "Common", + "value": "0.6 - 1.3 mg" + }, + { + "name": "Strong", + "value": "1.3 - 2.4 mg" + }, + { + "name": "Heavy", + "value": "2.4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 18 hours" + }, + { + "name": "Onset", + "value": "40 - 80 minutes" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "After effects", + "value": "1 - 3 days" + } + ], + "bioavailability": "30%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.2 mg" + }, + { + "name": "Light", + "value": "0.2 - 0.4 mg" + }, + { + "name": "Common", + "value": "0.4 - 0.8 mg" + }, + { + "name": "Strong", + "value": "0.8 - 1.5 mg" + }, + { + "name": "Heavy", + "value": "1.5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "After effects", + "value": "1 - 3 days" + } + ], + "bioavailability": "48%" + }, + { + "name": "Low", + "duration": [ + { + "name": "Duration", + "value": "Dose hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 219, + "name": "Bupropion", + "aliases": [ + "amfebutamone", + "wellbutrin", + "zyban" + ], + "aliasesStr": "amfebutamone,wellbutrin,zyban", + "url": "https://drugs.tripsit.me/bupropion", + "experiencesUrl": null, + "summary": "A frequently prescribed atypical antidepressant. Occasionally prescribed as an aid to smoking cessation. May lower seizure threshold in predisposed individuals. Poorly understood mechanism of action, probably an NDRI. Avoid combination with other drugs.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Parent", + "duration": [ + { + "name": "Duration", + "value": "11-21 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Metabolites", + "duration": [ + { + "name": "Duration", + "value": "20-37 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 220, + "name": "Butylone", + "aliases": [ + "b1", + "bk-mbdb", + "bk-methyl-j" + ], + "aliasesStr": "b1,bk-mbdb,bk-methyl-j", + "url": "https://psychonautwiki.org/wiki/Butylone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_bkMBDB.shtml", + "summary": "Empathogen and stimulant of the cathinone class.", + "reagents": null, + "classes": { + "chemical": [ + "MDxx", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 80 mg" + }, + { + "name": "Common", + "value": "80 - 125 mg" + }, + { + "name": "Strong", + "value": "125 - 225 mg" + }, + { + "name": "Heavy", + "value": "225 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "60 - 120 minutes" + }, + { + "name": "Offset", + "value": "60 - 120 minutes" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 221, + "name": "Butyrfentanyl", + "aliases": [ + "b-f", + "bf" + ], + "aliasesStr": "b-f,bf", + "url": "https://drugs.tripsit.me/butyrfentanyl", + "experiencesUrl": null, + "summary": "Potent short-acting opioid and fentanyl analogue. Often dispensed in a nasal spray. This is an highly potent drug - exercise extreme caution. May cause respiratory depression and death in overdose.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "400-800ug" + }, + { + "name": "Common", + "value": "800-1500ug" + }, + { + "name": "Strong", + "value": "1.5-3mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 222, + "name": "BZP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/bzp", + "experiencesUrl": null, + "summary": "A stimulant that was sold as \"legal ecstasy\" in the late 2000s, and was one of the first drugs widely marketed as a \"research chemical.\" It has a much less favourable effect profile and has fallen out of popularity greatly since it was banned in many countries.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "40-70mg" + }, + { + "name": "Common", + "value": "70-100mg" + }, + { + "name": "Strong", + "value": "100-130mg" + }, + { + "name": "Heavy", + "value": "130mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 223, + "name": "C30-NBOMe", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/c30-nbome", + "experiencesUrl": null, + "summary": "Inactive, if you do feel effects from \"C30-NBOMe\" you're either having the placebo effect of the world, or are being sold something else, and I recommend you send it in for testing somewhere.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 224, + "name": "Caffeine", + "aliases": [ + "coffee" + ], + "aliasesStr": "coffee", + "url": "https://psychonautwiki.org/wiki/Caffeine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Caffeine.shtml", + "summary": "Caffeine is a a CNS stimulant, and also the most widely used psychoactive substance in the world. It is legal and unregulated in most parts of the world, and is found in many commonly sold products. It has a good safety profile, though regular heavy use can cause physical dependence and contribute to certain medical conditions.", + "reagents": null, + "classes": { + "chemical": [ + "Xanthines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "The LD50 of caffeine in humans is dependent on individual sensitivity, but is estimated to be about 150 to 200 milligrams per kilogram of body mass or roughly 80 to 100 cups of coffee for an average adult" + ], + "addictionPotential": "produces dependence with chronic use and has a low abuse potential", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 500 mg" + }, + { + "name": "Heavy", + "value": "500 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "10 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "6 - 10 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2.5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2.5 hours" + }, + { + "name": "Onset", + "value": "0.5 - 2 minutes" + }, + { + "name": "Come up", + "value": "0.5 - 2 minutes" + }, + { + "name": "Peak", + "value": "0.5 - 1 hours" + }, + { + "name": "Offset", + "value": "6 - 10 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "10-20mg" + }, + { + "name": "Light", + "value": "20-75mg" + }, + { + "name": "Common", + "value": "75mg-250mg" + }, + { + "name": "Strong", + "value": "250-400mg" + }, + { + "name": "Heavy", + "value": "400mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "1.5-5 hours" + }, + { + "name": "After effects", + "value": "3-4 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Low Risk & No Synergy", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.", + "name": "2C-T-x" + }, + { + "status": "Low Risk & No Synergy", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.", + "name": "2C-x" + }, + { + "status": "Low Risk & No Synergy", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.", + "name": "5-MeO-xxT" + }, + { + "status": "Low Risk & No Synergy", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "This combination of stimulants is not generally necessary and may increase strain on the heart, as well as potentially causing anxiety and greater physical discomfort.", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "Both stimulants, risk of tachycardia, hypertension, and in extreme cases heart failure.", + "name": "Cocaine" + }, + { + "status": "Low Risk & No Synergy", + "name": "DMT" + }, + { + "status": "Caution", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating it may cause some physical discomfort.", + "name": "DOx" + }, + { + "status": "Low Risk & No Synergy", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.", + "name": "DXM" + }, + { + "status": "Low Risk & No Synergy", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & No Synergy", + "note": "No unexpected interactions.", + "name": "Ketamine" + }, + { + "status": "Low Risk & No Synergy", + "name": "LSD" + }, + { + "status": "Low Risk & No Synergy", + "name": "MAOIs" + }, + { + "status": "Caution", + "note": "Caffiene is not really necessary with MDMA and increases any neurotoxic effects from MDMA", + "name": "MDMA" + }, + { + "status": "Low Risk & No Synergy", + "note": "No likely interactions", + "name": "MXE" + }, + { + "status": "Low Risk & No Synergy", + "note": "High doses of caffeine are uncomfortable and this will be magnified by psychedelics", + "name": "Mescaline" + }, + { + "status": "Low Risk & No Synergy", + "name": "Mushrooms" + }, + { + "status": "Caution", + "note": "Caffiene can bring out the natural stimulation from psychedelic drugs to make it uncomfortable. High doses can cause anxiety which is hard to handle while tripping", + "name": "NBOMes" + }, + { + "status": "Low Risk & No Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & No Synergy", + "name": "Opioids" + }, + { + "status": "Caution", + "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.", + "name": "PCP" + }, + { + "status": "Low Risk & No Synergy", + "name": "SSRIs" + }, + { + "status": "Low Risk & No Synergy", + "name": "Tramadol" + }, + { + "status": "Caution", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.", + "name": "aMT" + } + ] + }, + { + "id": 225, + "name": "Cake", + "aliases": [ + "caky", + "cokoo" + ], + "aliasesStr": "caky,cokoo", + "url": "https://psychonautwiki.org/wiki/Cake", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": null, + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25g-30g" + }, + { + "name": "Light", + "value": "30g-65g" + }, + { + "name": "Common", + "value": "65g-100g" + }, + { + "name": "Strong", + "value": "100g-300g" + }, + { + "name": "Heavy", + "value": "300g-500g" + } + ], + "duration": null, + "bioavailability": "90%" + } + ], + "interactions": null + }, + { + "id": 226, + "name": "Camazepam", + "aliases": [ + "albego", + "limpidon", + "paxor" + ], + "aliasesStr": "albego,limpidon,paxor", + "url": "https://drugs.tripsit.me/camazepam", + "experiencesUrl": null, + "summary": "A benzodiazepine drug that is stronger in terms of anxiety relief than it is in terms of how hypnotic it is. It is a metabolite of diazepam and has limited anticonvulsant properties.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Heavy", + "value": "40+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 227, + "name": "Cannabidiol", + "aliases": [ + "cbd", + "epidiolex" + ], + "aliasesStr": "cbd,epidiolex", + "url": "https://psychonautwiki.org/wiki/Cannabidiol", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Cannabinoid" + ], + "psychoactive": null + }, + "toxicity": [ + "well-tolerated and shows little to no toxicity" + ], + "addictionPotential": "low abuse potential", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 4 hours" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 228, + "name": "Cannabis", + "aliases": [ + "bud", + "dagga", + "grass", + "green", + "hash", + "herb", + "marijuana", + "mary jane", + "pot", + "thc", + "tree", + "weed" + ], + "aliasesStr": "bud,dagga,grass,green,hash,herb,marijuana,mary jane,pot,thc,tree,weed", + "url": "https://psychonautwiki.org/wiki/Cannabis", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Cannabis.shtml", + "summary": "A common and widely used psychoactive plant, which is beginning to enjoy legal status for medical and even recreational use in some parts of the world. Usually smoked or eaten, primary effects are relaxation and an affinity towards food - a state described as being 'stoned.'", + "reagents": null, + "classes": { + "chemical": [ + "Cannabinoid" + ], + "psychoactive": null + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "moderately habit-forming", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "1 - 2 weeks", + "zero": "2 - 3 weeks" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "33 - 66 mg" + }, + { + "name": "Common", + "value": "66 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "0 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "45 - 180 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg (THC)" + }, + { + "name": "Light", + "value": "2.5 - 5 mg (THC)" + }, + { + "name": "Common", + "value": "5 - 10 mg (THC)" + }, + { + "name": "Strong", + "value": "10 - 25 mg (THC)" + }, + { + "name": "Heavy", + "value": "25 mg + (THC)" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 120 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "2C-T-x" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "2C-x" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "5-MeO-xxT" + }, + { + "status": "Low Risk & Synergy", + "note": "In excess, this combination can cause nausea.", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Caffeine" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Cocaine" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "DMT" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "DOx" + }, + { + "status": "Low Risk & Synergy", + "name": "DXM" + }, + { + "status": "Low Risk & Synergy", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "LSD" + }, + { + "status": "Low Risk & Synergy", + "name": "MAOIs" + }, + { + "status": "Low Risk & Synergy", + "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible.", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "MXE" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "Mescaline" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "Mushrooms" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & Synergy", + "name": "Opioids" + }, + { + "status": "Low Risk & Synergy", + "name": "PCP" + }, + { + "status": "Low Risk & No Synergy", + "name": "SSRIs" + }, + { + "status": "Low Risk & Synergy", + "name": "Tramadol" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics. Small amounts can reduce nausea with aMT but take care.", + "name": "aMT" + } + ] + }, + { + "id": 229, + "name": "Carisoprodol", + "aliases": [ + "soma" + ], + "aliasesStr": "soma", + "url": "https://psychonautwiki.org/wiki/Carisoprodol", + "experiencesUrl": null, + "summary": "A skeletal muscle relaxant drug also known as Soma, carisoprodol has limited recreational value, however its main metabolite meprobamate has some moderate tranquilising properties. Sometimes found in concoctions with codeine or caffeine.", + "reagents": null, + "classes": { + "chemical": [ + "Carbamate" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 325 mg" + }, + { + "name": "Common", + "value": "325 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 750 mg" + }, + { + "name": "Heavy", + "value": "750 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "After effects", + "value": "1 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 230, + "name": "Phenylpiracetam", + "aliases": [ + "carphedon", + "phenotropil" + ], + "aliasesStr": "carphedon,phenotropil", + "url": "https://psychonautwiki.org/wiki/Phenylpiracetam", + "experiencesUrl": null, + "summary": "A nootropic and piracetam analogue also known as fonturacetam, this drug has been shown to have potential memory enhancing, anxiolytic, anti-amnesia and anti-depressive effects, however has little recreational value. Around 45x more potent than Piracetam.", + "reagents": null, + "classes": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Stimulants", + "Nootropic" + ] + }, + "toxicity": [ + "safe even when high doses are consumed for a long period of time", + "exact toxic dosage is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "racetam", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 400 mg" + }, + { + "name": "Heavy", + "value": "400 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours (some users have reported effects lasting an entire day)" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 hour" + } + ] + } + ], + "interactions": null + }, + { + "id": 231, + "name": "Centrophenoxine", + "aliases": [ + "lucidril", + "meclofenoxate" + ], + "aliasesStr": "lucidril,meclofenoxate", + "url": "https://drugs.tripsit.me/centrophenoxine", + "experiencesUrl": null, + "summary": "Cholinergic compound with a DMAE compotent. Is thought to help in reversing some signs of aging. Naturally found substance, most notably in fish.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 232, + "name": "Changa", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/changa", + "experiencesUrl": null, + "summary": "Changa is the name given to a smoking blend of caapi or other MAOI containing plants with an infusion of extracted DMT. Changa often contains other milder psychoactive herbs as well. The maoi action results in a longer and more intense trip (see Ayahuasca) NOTE: There is no standardized recipe or concentration of infused DMT, therefor dosage and potency will vary per batch.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-50mg" + }, + { + "name": "Heavy", + "value": "50+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "0-2 minutes" + }, + { + "name": "Duration", + "value": "6-12 minutes" + }, + { + "name": "After effects", + "value": "1-36 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 233, + "name": "Chloral betaine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/chloral-betaine", + "experiencesUrl": null, + "summary": "Sedative-hypnotic drug that was introduced into the United States in the 60's. Betaine complex with Chloral hydrate, thus makes it act as an extended version of Chloral hydrate then to Trichloroethanol, which is responsible for most of its effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "125-250mg" + }, + { + "name": "Common", + "value": "250-500mg." + }, + { + "name": "Strong", + "value": "500-1000mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "3-7 hours" + }, + { + "name": "After effects", + "value": "2-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 234, + "name": "Chloroform", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/chloroform", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Chloroform.shtml", + "summary": "A naturally occurring organic compound once used as an anaesthetic. Has practically disappeared in this usage due to numerous harmful effects including danger of sudden death through cardiac arrhythmia. Has been implicated in numerous murders. Highly unsafe.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 235, + "name": "Choline bitartrate", + "aliases": [ + "choline" + ], + "aliasesStr": "choline", + "url": "https://psychonautwiki.org/wiki/Choline_bitartrate", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Ammonium_salt" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "7 days", + "zero": "14 days" + }, + "crossTolerances": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 250 mg" + }, + { + "name": "Common", + "value": "250 - 1000 mg" + }, + { + "name": "Strong", + "value": "1000 - 2000 mg" + }, + { + "name": "Heavy", + "value": "2000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "45 - 75 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 8 hours" + } + ], + "bioavailability": "40%" + } + ], + "interactions": null + }, + { + "id": 236, + "name": "Tadalafil", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/cialis", + "experiencesUrl": null, + "summary": "Tadalafil, a PDE5 inhibitor used to combat erectile disfunction. Dangerous in combination with other drugs which lower blood pressure.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg." + } + ], + "duration": [ + { + "name": "Duration", + "value": "4-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 237, + "name": "Cinolazepam", + "aliases": [ + "geroderm" + ], + "aliasesStr": "geroderm", + "url": "https://drugs.tripsit.me/cinolazepam", + "experiencesUrl": null, + "summary": "A benzodiazepine derivative drug with anxiolytic effects but mainly hypnotic effects. It is extremely effective for sleep aid but has mild euphoria compared to other benzos", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-30mg" + }, + { + "name": "Common", + "value": "30-60mg" + }, + { + "name": "Strong", + "value": "60-120mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "12-20 hours" + } + ], + "bioavailability": "90-100%" + } + ], + "interactions": null + }, + { + "id": 238, + "name": "Citalopram", + "aliases": [ + "celexa", + "cipramil" + ], + "aliasesStr": "celexa,cipramil", + "url": "https://drugs.tripsit.me/citalopram", + "experiencesUrl": null, + "summary": "Citalopram is an SSRI that is used to treat depression. It does not lead to a high and causes a wide range of negative psychological and physical effects when people attempt to abuse it and can lead to serotonin syndrome and cause suicidal ideation. Those with bipolar disorder tend to go into a mixed state or manic states when trying SSRI's.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 239, + "name": "Citicoline", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Citicoline", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Ammonium_salt" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 250 mg" + }, + { + "name": "Common", + "value": "250 - 1000 mg" + }, + { + "name": "Strong", + "value": "1000 - 2000 mg" + }, + { + "name": "Heavy", + "value": "2000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "58 - 74 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "2.5 - 3.5 hours" + }, + { + "name": "Offset", + "value": "30 - 40 hours" + }, + { + "name": "After effects", + "value": "40 - 60 hours" + } + ], + "bioavailability": "98%" + } + ], + "interactions": null + }, + { + "id": 240, + "name": "Clobazam", + "aliases": [ + "frisium" + ], + "aliasesStr": "frisium", + "url": "https://drugs.tripsit.me/clobazam", + "experiencesUrl": null, + "summary": "A long acting benzodiazepine which focuses primarily on anxiolytic and anticonvulsant properties. It is used medically to treat epilepsy, and this along with its relatively many negative side-effects and contraindications in comparison with other benzodiazepines means it isn't frequently used recreationally.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Heavy", + "value": "15-30mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 241, + "name": "Clomethiazole", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/clomethiazole", + "experiencesUrl": null, + "summary": "Structurally related to Thiamine (vitamin B1), but with binding potential at the GABAa site, which causes it to produce effects most like those of a barbiturate: an effective sedative and hypnotic. Originally developed by Hoffman-LaRoche in the 1930s, it has seen use as a treatment for acute alcohol withdrawal.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100mg" + }, + { + "name": "Light", + "value": "100-150mg" + }, + { + "name": "Common", + "value": "150-200mg" + }, + { + "name": "Heavy", + "value": "200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-40 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 242, + "name": "Clonazepam", + "aliases": [ + "k-pins", + "klonopin", + "kpin", + "rivotril" + ], + "aliasesStr": "k-pins,klonopin,kpin,rivotril", + "url": "https://psychonautwiki.org/wiki/Clonazepam", + "experiencesUrl": null, + "summary": "A medium-length common prescription benzodiazepine, often used to treat panic attacks because of its relatively fast sublingual onset. Primarily anxiolytic, but also possessing of other benzo traits.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1 mg" + }, + { + "name": "Strong", + "value": "1 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "After effects", + "value": "8 - 48 hours" + } + ], + "bioavailability": "90%" + } + ], + "interactions": null + }, + { + "id": 243, + "name": "Clonazolam", + "aliases": [ + "c-lam", + "clam", + "clonitrazolam" + ], + "aliasesStr": "c-lam,clam,clonitrazolam", + "url": "https://psychonautwiki.org/wiki/Clonazolam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Clonazolam.shtml", + "summary": "A long lasting benzodiazepine with heavily hypnotic effects. The safety profile is not well established, and there have been reports that people taking it three days in a row have had a seizure. Most comparable to Triazolam, but with a much longer half-life.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "75 - 200 µg" + }, + { + "name": "Common", + "value": "200 - 400 µg" + }, + { + "name": "Strong", + "value": "400 - 1 mg" + }, + { + "name": "Heavy", + "value": "1 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 244, + "name": "Clonidine", + "aliases": [ + "catapres", + "catapres-tts", + "duraclon", + "kapvay", + "nexiclon xr" + ], + "aliasesStr": "catapres,catapres-tts,duraclon,kapvay,nexiclon xr", + "url": "https://psychonautwiki.org/wiki/Clonidine", + "experiencesUrl": null, + "summary": "Is a medication that is used to treat high blood pressure, anxiety, withdrawal (Typically from Alcohol, Opioids, Smoking) and many other uses.", + "reagents": null, + "classes": { + "chemical": [ + "Imidazoline" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": null, + "addictionPotential": "not addictive and has a low potential for abuse", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 μg" + }, + { + "name": "Light", + "value": "50 - 75 μg" + }, + { + "name": "Common", + "value": "75 - 100 μg" + }, + { + "name": "Strong", + "value": "100 - 300 μg" + }, + { + "name": "Heavy", + "value": "300 μg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "6 - 8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 245, + "name": "Cloniprazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/cloniprazepam", + "experiencesUrl": null, + "summary": "Prodrug for Clonazepam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": ".5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "6-9 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 246, + "name": "Clonitazene", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/clonitazene", + "experiencesUrl": null, + "summary": "An opioid that is roughly three times as potent as Morphine. Is related to Etonitazene, which is about 1000-1500x the potency of Morphine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Strong", + "value": "10-15mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 247, + "name": "Clorazepate", + "aliases": [ + "novo-clopate", + "tranxene", + "tranzene" + ], + "aliasesStr": "novo-clopate,tranxene,tranzene", + "url": "https://drugs.tripsit.me/clorazepate", + "experiencesUrl": null, + "summary": "Is a prodrug for Desmethyldiazepam which is responsible for most of the therapeutic effects. Has a long half life, with the addition of Desmethyldiazepam as the main metabolite, which makes it much longer.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-40mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-80 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ], + "bioavailability": "91%" + } + ], + "interactions": null + }, + { + "id": 248, + "name": "Clotiazepam", + "aliases": [ + "clozan", + "distensan", + "rize", + "rizen", + "trecalmo", + "veratran" + ], + "aliasesStr": "clozan,distensan,rize,rizen,trecalmo,veratran", + "url": "https://drugs.tripsit.me/clotiazepam", + "experiencesUrl": null, + "summary": "Is a thienodiazepine substance. It differs from most other benzodiazepines in which the benzene ring has been replaced by a thiophene ring.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "4-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 249, + "name": "Cloxazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/cloxazolam", + "experiencesUrl": null, + "summary": "Benzodiazepine derivate that is metabolised into Delorazepam. Which is where most of its effects come from.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "1.5-3mg" + }, + { + "name": "Common", + "value": "3-6mg" + }, + { + "name": "Strong", + "value": "6-12mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "7-12 hours" + }, + { + "name": "After effects", + "value": "4-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 250, + "name": "Cocaine", + "aliases": [ + "blow", + "coke", + "crack", + "girl", + "nose candy", + "snow", + "white" + ], + "aliasesStr": "blow,coke,crack,girl,nose candy,snow,white", + "url": "https://psychonautwiki.org/wiki/Cocaine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Cocaine.shtml", + "summary": "A highly popular, short acting CNS stimulant that works by blocking the reuptake of dopamine, serotonin, and norepinephrine. It is known to increase euphoria, confidence, sex-drive, focus, body temperature, and heart rate. Cocaine can cause severe vasoconstriction and is known to be cardiotoxic and have a high potential for compulsive redosing and addiction.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tropanes" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "individuals have died from as little as 30 mg applied to mucous membranes, whereas addicts may tolerate up to 5 grams daily" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Inhaled", + "dosage": null, + "duration": null + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 90 minutes" + }, + { + "name": "Onset", + "value": "1 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 15 minutes" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "10 - 30 minutes" + } + ], + "bioavailability": "60-80%" + } + ], + "interactions": [ + { + "status": "Unsafe", + "note": "Cocaine and 2c-t-x both provide considerable stimulation. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.", + "name": "2C-T-x" + }, + { + "status": "Caution", + "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics. Combination of the stimulating effects may be uncomfortable.", + "name": "2C-x" + }, + { + "status": "Unsafe", + "note": "The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics. ", + "name": "5-MeO-xxT" + }, + { + "status": "Unsafe", + "note": "Drinking on stimulants is risky because the sedative effects of the alcohol are reduced, and these are what the body uses to gauge drunkenness. This typically leads to excessive drinking with greatly reduced inhibitions, high risk of liver damage and increased dehydration. They will also allow you to drink past a point where you might normally pass out, increasing the risk. If you do decide to do this then you should set a limit of how much you will drink each hour and stick to it, bearing in mind that you will feel the alcohol less. Cocaine is potentiated somewhat by alcohol because of the formation of cocaethylene.", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "This combination of stimulants will increase strain on the heart. It is not generally worth it as cocaine has a mild blocking effect on dopamine releasers like amphetamine", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Caution", + "note": "Both stimulants, risk of tachycardia, hypertension, and in extreme cases heart failure.", + "name": "Caffeine" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "DMT" + }, + { + "status": "Unsafe", + "note": "The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of cocaine can easily lead to thought loops. Coming down from cocaine while the DOx is still active can be quite anxiogenic", + "name": "DOx" + }, + { + "status": "Unsafe", + "note": "Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues", + "name": "DXM" + }, + { + "status": "Caution", + "note": "Stimulants increase respiration rate allowing a higher dose of sedatives. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest. Likewise the G can wear off and leave a dangerous concentration of cocaine behind", + "name": "GHB/GBL" + }, + { + "status": "Caution", + "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.", + "name": "Ketamine" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "LSD" + }, + { + "status": "Dangerous", + "note": "This combination is poorly explored", + "name": "MAOIs" + }, + { + "status": "Caution", + "note": "Cocaine blocks some of the desirable effects of MDMA while increasing the risk of heart attack.", + "name": "MDMA" + }, + { + "status": "Caution", + "note": "Stimulants taken with MXE can lead to hypermanic states much more easily, especially if sleep is avoided.", + "name": "MXE" + }, + { + "status": "Caution", + "note": "The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops", + "name": "Mescaline" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Mushrooms" + }, + { + "status": "Unsafe", + "note": "Cocaine and NBOMes both provide considerable stimulation. When combined they can result in severe vasoconstriction, tachycardia, hypertension, and in extreme cases heart failure.", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Dangerous", + "note": "Stimulants increase respiration rate allowing a higher dose of opiates. If the stimulant wears off first then the opiate may overcome the patient and cause respiratory arrest.", + "name": "Opioids" + }, + { + "status": "Unsafe", + "note": "This combination can easily lead to hypermanic states", + "name": "PCP" + }, + { + "status": "Low Risk & No Synergy", + "note": "May reduce each others' effectiveness. Cocaine can reduce mental stability and therefore exacerbate conditions which SSRIs are used to treat.", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "note": "Tramadol and stimulants both increase the risk of seizures.", + "name": "Tramadol" + }, + { + "status": "Dangerous", + "name": "aMT" + } + ] + }, + { + "id": 251, + "name": "Codeine", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Codeine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Codeine.shtml", + "summary": "Codeine is a weaker opioid used to treat mild to moderate pain and to relieve cough. In many countries it is available over the counter in combination with paracetamol, which can easily be extracted to retrieve near-pure codeine. For this reason, it is used widely as a recreational opioid. It is metabolised into morphine in the body at a rate of 5% mg for mg.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": null, + "duration": null, + "bioavailability": "49.9 - 59.7%" + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + }, + { + "name": "Come up", + "value": "1 - 2 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + } + ], + "bioavailability": "90%" + } + ], + "interactions": null + }, + { + "id": 252, + "name": "Coluracetam", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Coluracetam", + "experiencesUrl": null, + "summary": "A nootropic drug of the racetam class, originally developed to treat Alzheimer's disease, it is currently being investigated as a treatment for major depressive disorder and generalised anxiety disorder. May be a modulator of the AMPA receptor. Limited recreational value.", + "reagents": null, + "classes": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "not addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "racetam", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + } + ] + }, + { + "name": "Sublingual/Insufflated", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Sublingual", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Intranasal", + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 253, + "name": "Coronaridine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/coronaridine", + "experiencesUrl": null, + "summary": "Alkaloid found in Tabernanthe iboga and related species. Persistently reduces the self-administration of Cocaine and Morphine in rats.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 254, + "name": "Creatine", + "aliases": [ + "methylguanidoacetic acid", + "n-carbamimidoyl-n-methylglycine" + ], + "aliasesStr": "methylguanidoacetic acid,n-carbamimidoyl-n-methylglycine", + "url": "https://psychonautwiki.org/wiki/Creatine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Nitrogenous_organic_acid" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": null, + "addictionPotential": "not habit-forming with a low potential for abuse", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 g" + }, + { + "name": "Light", + "value": "1 - 5 g" + }, + { + "name": "Common", + "value": "5 - 10 g" + }, + { + "name": "Strong", + "value": "10 - 20 g" + }, + { + "name": "Heavy", + "value": "20 g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 36 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 255, + "name": "CRL-40-940", + "aliases": [ + "bisfluoromodafinil", + "flmodafinil", + "lauflumide" + ], + "aliasesStr": "bisfluoromodafinil,flmodafinil,lauflumide", + "url": "https://drugs.tripsit.me/crl-40-940", + "experiencesUrl": null, + "summary": "Bisfluoro analogue Modafinil. Has been sold online as a research chemical. Was patented in 2013. Is slightly more potent than Armodafinil.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-75mg" + }, + { + "name": "Strong", + "value": "75-150mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 256, + "name": "CRL-40-941", + "aliases": [ + "fladrafinil", + "fluoromodafinil" + ], + "aliasesStr": "fladrafinil,fluoromodafinil", + "url": "https://drugs.tripsit.me/crl-40-941", + "experiencesUrl": null, + "summary": "A substance closely related to Adrafinil and Modafinil. It is the bis(p-fluoro) ring derivative of Adrafinil.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-250mg" + }, + { + "name": "Strong", + "value": "250-350mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "6-14 hours" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 257, + "name": "Cyclazodone", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Cyclazodone", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "4-oxazolidinone", + "Substituted_aminorexes" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": null, + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +", + "note": "Liver damage may result from heavy or sustained usage." + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 258, + "name": "Cyclizine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/cyclizine", + "experiencesUrl": null, + "summary": "First generation antihistamine and anticholinergic drug used to combat nausea and vomiting. Causes drowsiness. Like most antihistamines in high doses it induces delirium and vivid realistic hallucinations. Probably uncomfortable and not enjoyable.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "25-50mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "Oral hours" + }, + { + "name": "After effects", + "value": "14 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 259, + "name": "Cyclo-Methiodrone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/cyclo-methiodrone", + "experiencesUrl": null, + "summary": "Empathogen with strong stimulant effects, very loosely related to benzylpiperidine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "30-45mg" + }, + { + "name": "Common", + "value": "45-65mg" + }, + { + "name": "Strong", + "value": "65-90mg" + }, + { + "name": "Heavy", + "value": "90+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "25-45 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 260, + "name": "Cyclobenzaprine", + "aliases": [ + "apo-cyclobenzaprin", + "fexmid", + "flexeril", + "novo-cycloprine" + ], + "aliasesStr": "apo-cyclobenzaprin,fexmid,flexeril,novo-cycloprine", + "url": "https://drugs.tripsit.me/cyclobenzaprine", + "experiencesUrl": null, + "summary": "Muscle relaxant and CNS depressant used to relieve skeletal muscle spasms and associated pain in acute musculoskeletal conditions. Sometimes prescribed off-label for treatment of fibromyalgia or as a sleep aid. Has little recreational value alone, but may potentiate some opioids. May cause drowsiness, dry mouth and dizziness.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg" + }, + { + "name": "Heavy", + "value": "15mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 261, + "name": "CYCLOPENTYL-FENTANYL", + "aliases": [ + "cp-f", + "cpf" + ], + "aliasesStr": "cp-f,cpf", + "url": "https://drugs.tripsit.me/cyclopentyl-fentanyl", + "experiencesUrl": null, + "summary": "An analogue of fentanyl that is unknown in literature, seems to be less potent than its former being Acetyl-Fentanyl. Yet reports have yet to surface. Be careful.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 262, + "name": "Cyclopropylmescaline", + "aliases": [ + "4-cyclopropylmethoxy-3", + "cpm" + ], + "aliasesStr": "4-cyclopropylmethoxy-3,cpm", + "url": "https://drugs.tripsit.me/cyclopropylmescaline", + "experiencesUrl": null, + "summary": "Cyclopropylmescaline, AKA CPM, is a psychedelic/hallucinogenic that was produced by Alexander Shulgin. It causes visual and auditory hallucinations and lasts quite a long time. Little is known about it so caution must be used when trying out this substance.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-60mg" + }, + { + "name": "Common", + "value": "60-70mg" + }, + { + "name": "Strong", + "value": "70-80mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "12-18 hours" + }, + { + "name": "After effects", + "value": "6-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 263, + "name": "D2PM", + "aliases": [ + "diphenylprolinol" + ], + "aliasesStr": "diphenylprolinol", + "url": "https://drugs.tripsit.me/d2pm", + "experiencesUrl": null, + "summary": "An NDRI, which is reported as being rather lackluster.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "15-20mg" + }, + { + "name": "Common", + "value": "20-35mg" + }, + { + "name": "Strong", + "value": "35-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-30 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 264, + "name": "DALT", + "aliases": [ + "diallyltryptamine", + "n,n-diallyltryptamine" + ], + "aliasesStr": "diallyltryptamine,n,n-diallyltryptamine", + "url": "https://drugs.tripsit.me/dalt", + "experiencesUrl": null, + "summary": "Psychedelic drug of the tryptamine class.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "none", + "dosage": [ + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 265, + "name": "Datura", + "aliases": [ + "jimson weed" + ], + "aliasesStr": "jimson weed", + "url": "https://psychonautwiki.org/wiki/Datura", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Datura.shtml", + "summary": "A family of plants containing various Tropane alkaloids. Produces long-lasting deliriant effects including very realistic and often unpleasant hallucinations along with short-term amnesia. Datura plants are toxic to humans, and potency varies greatly from plant-to-plant, making the drug extremely difficult to dose safely. Not typically regarded as recreational.", + "reagents": null, + "classes": { + "chemical": null, + "psychoactive": [ + "Deliriant" + ] + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "mildly addictive with a high potential for adverse side effects such as psychosis", + "tolerance": { + "full": "with repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "8 - 18 hours" + }, + { + "name": "Onset", + "value": "20 - 120 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "5 - 12 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 266, + "name": "Datura (botany)", + "aliases": [ + "angel's trumpets", + "devil's trumpets", + "devil's weed", + "hell's bells", + "jimsonweed", + "moonflowers", + "thorn-apple" + ], + "aliasesStr": "angel's trumpets,devil's trumpets,devil's weed,hell's bells,jimsonweed,moonflowers,thorn-apple", + "url": "https://psychonautwiki.org/wiki/Datura_(botany)", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 267, + "name": "DB-MDBP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/db-mdbp", + "experiencesUrl": null, + "summary": "Inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 268, + "name": "Dehydroxyfluorafinil", + "aliases": [ + "modafiendz" + ], + "aliasesStr": "modafiendz", + "url": "https://drugs.tripsit.me/dehydroxyfluorafinil", + "experiencesUrl": null, + "summary": "Nootropic of the benzhydryl class. Closely related to Adrafinil and Modafinil. Was branded as \"Modafiendz\" through some research chemical vendors.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Threshold", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "150-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 269, + "name": "Delorazepam", + "aliases": [ + "nordiclazepam" + ], + "aliasesStr": "nordiclazepam", + "url": "https://drugs.tripsit.me/delorazepam", + "experiencesUrl": null, + "summary": "Also known as chlordesmethyldiazepam, this uncommon benzodiazepine compound is primarily used for treatment of anxiety and alcohol withdrawal, due to its long half-life (60-140 hours). It is also the active metabolite of diclazepam and cloxazolam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.25-0.5mg" + }, + { + "name": "Common", + "value": "0.5-1.5mg" + }, + { + "name": "Strong", + "value": "1.5-2mg" + }, + { + "name": "Heavy", + "value": "2-3mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "12-16 hours" + }, + { + "name": "After effects", + "value": "72 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 270, + "name": "Pethidine", + "aliases": [ + "demerol", + "dolantin", + "dolcontral", + "meperidine" + ], + "aliasesStr": "demerol,dolantin,dolcontral,meperidine", + "url": "https://psychonautwiki.org/wiki/Pethidine", + "experiencesUrl": null, + "summary": "A phenylpiperidine opioid first synthesised by Otto Eisleb in 1939, better known by the names meperidine and pethidine. An analgesic, once widely prescribed it has since declined in usage due to the discovery of a toxic metabolite - norpethidine. Also reacts dangerously with many drugs.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_piperidines" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "high toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 - 50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 400 mg" + }, + { + "name": "Heavy", + "value": "400 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "2 - 10 hours" + } + ], + "bioavailability": "50-60%" + } + ], + "interactions": null + }, + { + "id": 271, + "name": "Deschloroetizolam", + "aliases": [ + "etizolam-2" + ], + "aliasesStr": "etizolam-2", + "url": "https://psychonautwiki.org/wiki/Deschloroetizolam", + "experiencesUrl": null, + "summary": "A Thienodiazepine which is close to its parent compound, Etizolam, whilst being significantly weaker and longer lasting.", + "reagents": null, + "classes": { + "chemical": [ + "Thienodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepine", + "thienodiazepine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 6 mg" + }, + { + "name": "Strong", + "value": "6 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 10 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "3 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 272, + "name": "Deschloroketamine", + "aliases": [ + "2'-oxo-pcm", + "2-oxo-pcm", + "dck", + "dxe", + "o-pcm", + "opcm" + ], + "aliasesStr": "2'-oxo-pcm,2-oxo-pcm,dck,dxe,o-pcm,opcm", + "url": "https://psychonautwiki.org/wiki/Deschloroketamine", + "experiencesUrl": null, + "summary": "A novel analogue of Ketamine which is much more potent and has a longer duration.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 90 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "3 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "3 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 273, + "name": "Desmethylflunitrazepam", + "aliases": [ + "fonazepam", + "norflunitrazepam", + "ro05-4435" + ], + "aliasesStr": "fonazepam,norflunitrazepam,ro05-4435", + "url": "https://drugs.tripsit.me/desmethylflunitrazepam", + "experiencesUrl": null, + "summary": "Benzodiazepine that is a metabolite of Flunitrazepam, and has been sold as a research chemical.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "2-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 274, + "name": "Desomorphine", + "aliases": [ + "krok", + "krokodil" + ], + "aliasesStr": "krok,krokodil", + "url": "https://psychonautwiki.org/wiki/Desomorphine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 275, + "name": "DET", + "aliases": [ + "diethyltryptamine" + ], + "aliasesStr": "diethyltryptamine", + "url": "https://psychonautwiki.org/wiki/DET", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DET.shtml", + "summary": "A surprisingly uncommon analogue of DMT with similar effects and reported oral activity without the aid of an MAOI.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "2 - 8 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "15-25mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Strong", + "value": "50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 276, + "name": "Dexedrine", + "aliases": [ + "dexamfetamine", + "dextroamphetamine" + ], + "aliasesStr": "dexamfetamine,dextroamphetamine", + "url": "https://drugs.tripsit.me/dexedrine", + "experiencesUrl": null, + "summary": "A highly abusable stimulant. It is rarely prescribed in the US to treat ADHD, and is very similar in effects to Adderall, as its main ingredient is 75% of what adderall is.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-30mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 277, + "name": "DXM", + "aliases": [ + "delsym", + "dex", + "dexalone", + "dextromethorphan", + "dm", + "dmo", + "duract", + "robitussin", + "robo", + "robotussin", + "syrup" + ], + "aliasesStr": "delsym,dex,dexalone,dextromethorphan,dm,dmo,duract,robitussin,robo,robotussin,syrup", + "url": "https://psychonautwiki.org/wiki/Dextromethorphan", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DXM.shtml", + "summary": "Commonly found in certain over the counter cough medicines. Has dissociative effects similar to ketamine or MXE, though also shares properties with opioids and alcohol. Make sure DXM is the only active ingredient in the preparation.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "produces dependence with chronic use and has moderate abuse potential", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociatives" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 mg" + }, + { + "name": "Light", + "value": "100 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 700 mg" + }, + { + "name": "Heavy", + "value": "700 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 120 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "3 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Unsafe", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Unsafe", + "note": "Little information exists about this combination.", + "name": "5-MeO-xxT" + }, + { + "status": "Dangerous", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Additionally CNS depression can lead to difficulty breathing. Avoid on anything higher than 1st plateau.", + "name": "Alcohol" + }, + { + "status": "Unsafe", + "note": "Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues.", + "name": "Amphetamines" + }, + { + "status": "Caution", + "note": "Small doses of benzos can end a bad trip, but both substances potentiate the ataxia and sedation caused by the other and this can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position.", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "note": "High doses of caffeine may cause anxiety which is less manageable when tripping, and since both are stimulating the combination may cause some physical discomfort.", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "name": "Cannabis" + }, + { + "status": "Unsafe", + "note": "Both substances raise heart rate, in extreme cases, panic attacks caused by these drugs have led to more serious heart issues", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Unsafe", + "note": "The DOx class as psychedelic stimulants have the potential to mask the effects of DXM and could lead to redosing to an unsafe level. DXM can also potentiate DOx resulting in an unpleasantly intense experience.", + "name": "DOx" + }, + { + "status": "Dangerous", + "note": "Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the patient falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position. This combination is hard to predict", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & No Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Dangerous", + "note": "High risk of serotonin syndrome", + "name": "MAOIs" + }, + { + "status": "Dangerous", + "name": "MDMA" + }, + { + "status": "Low Risk & No Synergy", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Unsafe", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Dangerous", + "note": "CNS depression, difficult breathing, heart issues, hepatoxic, just very unsafe combination all around. Additionally if one takes dxm, their tolerance of opiates goes down slightly, thus causing additional synergistic effects.", + "name": "Opioids" + }, + { + "status": "Dangerous", + "name": "PCP" + }, + { + "status": "Dangerous", + "note": "High risk of serotonin syndrome.", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "name": "Tramadol" + }, + { + "status": "Dangerous", + "name": "aMT" + } + ] + }, + { + "id": 278, + "name": "Dextropropoxyphene", + "aliases": [ + "capadex", + "co-proxamol", + "coproxamol", + "darvocet", + "darvon", + "di-gesic", + "propoxyphene" + ], + "aliasesStr": "capadex,co-proxamol,coproxamol,darvocet,darvon,di-gesic,propoxyphene", + "url": "https://psychonautwiki.org/wiki/Dextropropoxyphene", + "experiencesUrl": null, + "summary": "An opioid analgesic that is an optical isomer of levopropoxyphene. Used to treat mild pain and often used for its antitussive properties. It has been taken off the market in Europe and US due to concerns of health issues relating to the Kidney, Liver, Heart and Respiratory Disorders. Just a bit stronger than Tramadol.", + "reagents": null, + "classes": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "high toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "known to cause potentially fatal heart arrhythmias" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "30 - 65 mg" + }, + { + "name": "Common", + "value": "65 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 6 hours" + } + ], + "bioavailability": "40%" + } + ], + "interactions": null + }, + { + "id": 279, + "name": "Diazepam", + "aliases": [ + "apaurin", + "diastat", + "mother's little helper", + "valium" + ], + "aliasesStr": "apaurin,diastat,mother's little helper,valium", + "url": "https://psychonautwiki.org/wiki/Diazepam", + "experiencesUrl": null, + "summary": "A very common and widely prescribed benzodiazepine with hypnotic and sedative qualities. The metre by which other benzodiazepines are compared. May cause amnesia and lowered inhibitions in excess. Has a relatively long half-life in comparison with other benzodiazepines.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7-14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2.5 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "After effects", + "value": "12 - 36 hours" + } + ], + "bioavailability": "85-100%" + } + ], + "interactions": null + }, + { + "id": 280, + "name": "Dibutylone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/dibutylone", + "experiencesUrl": null, + "summary": "Inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 281, + "name": "RTI-111", + "aliases": [ + "dichloropane" + ], + "aliasesStr": "dichloropane", + "url": "https://psychonautwiki.org/wiki/Dichloropane", + "experiencesUrl": null, + "summary": "Stimulant of the Phenyltropane class that acts as a SNDRI. Presumably it will have a slightly slower onset and bit longer duration than its parent compound Cocaine. Yet being the Tropane analogue of 3,4-CTMP.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tropanes" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "2 - 4 days", + "zero": "1 - 1.5 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2.5 mg" + }, + { + "name": "Light", + "value": "2.5 - 7.5 mg" + }, + { + "name": "Common", + "value": "7.5 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "40 - 75 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "Come up", + "value": "15 - 60 seconds" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "20 - 40 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 90 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-50mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 282, + "name": "Diclazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Diclazepam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Diclazepam.shtml", + "summary": "A benzodiazepine drug and analogue of diazepam first synthesised by Leo Sternbach at Hoffman-LaRoche in 1960, it has become prominent as an RC benzodiazepine on the grey market in recent years, particularly with the decline in etizolam availability. A sedative and hypnotic it is of intermediate to long half life with similar effects to diazepam, though 10x more potent.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within 3-4 days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "GABAergic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "10 - 45 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 283, + "name": "Diclofensine", + "aliases": [ + "ro8-4650" + ], + "aliasesStr": "ro8-4650", + "url": "https://drugs.tripsit.me/diclofensine", + "experiencesUrl": null, + "summary": "A triple monoamine reuptake inhibitor developed by Hoffman-LaRoche in the 1970s as an antidepressant but discontinued, probably due to high abuse potential. Has not become popular as a recreational drug at this time. Acts as an SNDRI, mostly inhibits dopamine and noradrenaline.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "12-15mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Heavy", + "value": "60-80mg" + } + ], + "duration": [ + { + "name": "Duration", + "value": "4-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 284, + "name": "Diethyl ether", + "aliases": [ + "ether" + ], + "aliasesStr": "ether", + "url": "https://drugs.tripsit.me/diethyl-ether", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ether.shtml", + "summary": "An industrial solvent which is sometimes used recreationally as a dissociative anaesthetic, with a short length of action. Effects are similar to alcohol. Leaves one's breath tasting and smelling strongly of ether for much longer than the experience lasts.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "6", + "duration": [ + { + "name": "After effects", + "value": "hours hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 285, + "name": "Dihydrocodeine", + "aliases": [ + "dhc" + ], + "aliasesStr": "dhc", + "url": "https://psychonautwiki.org/wiki/Dihydrocodeine", + "experiencesUrl": null, + "summary": "A weak semi-synthetic opioid analgesic and antitussive (anti-cough) drug. Often sold as a syrup in combination with aspirin or paracetamol. Not to be confused with the slightly less potent codeine.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 4 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + }, + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Heavy", + "value": "150-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 286, + "name": "Dimemebfe", + "aliases": [ + "5-meo-bfe" + ], + "aliasesStr": "5-meo-bfe", + "url": "https://drugs.tripsit.me/dimemebfe", + "experiencesUrl": null, + "summary": "Related in structure to 5-MeO-DMT, yet much less potent. Described as feeling somewhat similar to mushrooms, with some empathogenic effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-75mg" + }, + { + "name": "Strong", + "value": "75-125mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-40 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 287, + "name": "Dimethylone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/dimethylone", + "experiencesUrl": null, + "summary": "Inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 288, + "name": "DPH", + "aliases": [ + "benadryl", + "diphenhydramine", + "nytol", + "sominex", + "unisom sleepmelts", + "zzzquil" + ], + "aliasesStr": "benadryl,diphenhydramine,nytol,sominex,unisom sleepmelts,zzzquil", + "url": "https://psychonautwiki.org/wiki/Diphenhydramine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Diphenhydramine.shtml", + "summary": "An antihistamine which, when taken in smaller doses relieves allergies and insomnia. In larger doses works as a deliriant and can actually keep the user awake. Generally the 'high' of this drug is reported as dysphoric, potentially causing hallucinations indistinguishable from reality.", + "reagents": null, + "classes": { + "chemical": [ + "Ethanolamine" + ], + "psychoactive": [ + "Deliriant", + "Depressant" + ] + }, + "toxicity": [ + "fatal at amounts close to or exceeding 2 grams" + ], + "addictionPotential": "produces dependence with chronic use", + "tolerance": { + "full": "with repeated use", + "half": null, + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "deliriant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "100 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 700 mg" + }, + { + "name": "Heavy", + "value": "700 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 6 hours" + }, + { + "name": "After effects", + "value": "up to 24 hours" + } + ], + "bioavailability": "40-60%" + } + ], + "interactions": null + }, + { + "id": 289, + "name": "Diphenidine", + "aliases": [ + "dpd" + ], + "aliasesStr": "dpd", + "url": "https://psychonautwiki.org/wiki/Diphenidine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Diphenidine.shtml", + "summary": "A dissociative anaesthetic related to ephenidine with similar qualities to PCP and ketamine. Has seen some popularity as a recreational RC. Dosage curve has been reported as particularly steep, so care should be taken.", + "reagents": null, + "classes": { + "chemical": [ + "Diarylethylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "?? mg", + "note": "\"??\" is not a number." + }, + { + "name": "Light", + "value": "?? - 20 mg", + "note": "\"??\" is not a number." + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 55 mg" + }, + { + "name": "Heavy", + "value": "> 55 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 3 hours" + }, + { + "name": "Onset", + "value": "30 - 90 seconds" + }, + { + "name": "Peak", + "value": "0.5 - 2 hours" + }, + { + "name": "Offset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "2 - 5 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "40 - 65 mg" + }, + { + "name": "Common", + "value": "65 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 130 mg" + }, + { + "name": "Heavy", + "value": "> 130 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "4 - 24 Hours" + } + ] + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 290, + "name": "Dipipanone", + "aliases": [ + "diconal" + ], + "aliasesStr": "diconal", + "url": "https://drugs.tripsit.me/dipipanone", + "experiencesUrl": null, + "summary": "A powerful opioid of equivalent strength to morphine, rarely seen outside of medical environments. Often used to treat severe pain where morphine is contraindicated. Usually found in combination with the antihistamine Cyclizine, which potentiates it.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "3-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Intravenous", + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 291, + "name": "DiPT", + "aliases": [ + "diisopropyltryptamine" + ], + "aliasesStr": "diisopropyltryptamine", + "url": "https://psychonautwiki.org/wiki/DiPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DiPT.shtml", + "summary": "A rare tryptamine psychedelic closely related to DMT, with the interesting property of having little visual hallucinations, but strong auditory effects.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 60 minutes" + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 75 mg" + }, + { + "name": "Strong", + "value": "75 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "15mg" + }, + { + "name": "Light", + "value": "15-25mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Heavy", + "value": "50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "12-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 292, + "name": "DMAA", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/dmaa", + "experiencesUrl": null, + "summary": "Also known as methylhexanamine, this sympathetomimetic drug was developed as a nasal decongestant by Eli Lilly in the 1940s. It has been used as a weight loss aid and missold as a dietary supplement and component of some energy drinks. Carries a risk of heart attack, stroke and other life-threatening cardiovascular issues.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "20-50mg" + }, + { + "name": "Strong", + "value": "50-100mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Rapid." + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 293, + "name": "DMT", + "aliases": [ + "dimethyltryptamine", + "dmitry", + "n,n-dmt", + "the glory", + "the spirit molecule" + ], + "aliasesStr": "dimethyltryptamine,dmitry,n,n-dmt,the glory,the spirit molecule", + "url": "https://psychonautwiki.org/wiki/DMT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DMT.shtml", + "summary": "A popular and powerful psychedelic, typically used in two ways; either it is vapourised for a short 'breakthrough' experience, or it is taken in combination with an enzyme inhibitor for a long, intense trip (this is also known as ayahuasca or pharmahuasca).", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "tolerance": { + "full": "does not appear to occur", + "half": null, + "zero": null + }, + "crossTolerances": [ + "psychedelics" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60+ mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 20 minutes" + }, + { + "name": "Onset", + "value": "20 - 40 seconds" + }, + { + "name": "Come up", + "value": "1 - 3 minutes" + }, + { + "name": "Peak", + "value": "2 - 8 minutes" + }, + { + "name": "Offset", + "value": "1 - 6 minutes" + }, + { + "name": "After effects", + "value": "10 - 60 minutes" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "4 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "15 - 30 minutes" + }, + { + "name": "Onset", + "value": "2 - 10 seconds" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "2 - 5 minutes" + }, + { + "name": "Offset", + "value": "-" + } + ] + }, + { + "name": "Vapourised", + "dosage": [ + { + "name": "Threshold", + "value": "5-10mg" + }, + { + "name": "Light", + "value": "10-15mg" + }, + { + "name": "Common", + "value": "15-25mg" + }, + { + "name": "Strong", + "value": "25-35mg" + }, + { + "name": "Heavy", + "value": "35mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "15-60 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50-125mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "3-5 minutes" + }, + { + "name": "Duration", + "value": "45-60 minutes" + }, + { + "name": "After effects", + "value": "15-60 minutes" + } + ] + }, + { + "name": "Vaporized/smoked", + "duration": [ + { + "name": "Onset", + "value": "0-2 minutes" + }, + { + "name": "Duration", + "value": "3-10 minutes" + }, + { + "name": "After effects", + "value": "15-60 minutes" + } + ] + }, + { + "name": "Oral_MAOI", + "duration": [ + { + "name": "Onset", + "value": "20-45 minutes" + }, + { + "name": "Duration", + "value": "180-420 minutes" + }, + { + "name": "After effects", + "value": "15-60 minutes" + } + ] + } + ], + "interactions": [ + { + "status": "Low Risk & Synergy", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Low Risk & Synergy", + "name": "5-MeO-xxT" + }, + { + "status": "Low Risk & Decrease", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Caffeine" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DOx" + }, + { + "status": "Low Risk & Synergy", + "name": "DXM" + }, + { + "status": "Low Risk & Decrease", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Low Risk & Synergy", + "name": "MAOIs" + }, + { + "status": "Low Risk & Synergy", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Low Risk & Synergy", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & No Synergy", + "name": "Opioids" + }, + { + "status": "Low Risk & Synergy", + "name": "PCP" + }, + { + "status": "Low Risk & Decrease", + "name": "SSRIs" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.", + "name": "Tramadol" + }, + { + "status": "Low Risk & Synergy", + "name": "aMT" + } + ] + }, + { + "id": 294, + "name": "DOB", + "aliases": [ + "brolamfetamine", + "bromo-dma" + ], + "aliasesStr": "brolamfetamine,bromo-dma", + "url": "https://psychonautwiki.org/wiki/DOB", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DOB.shtml", + "summary": "DOB is a relatively uncommon synthetic psychedelic. It is best known for its very low doses and long duration. Historically it has rarely been taken deliberately, but in place of LSD, however it has recently found its own place in the research chemical scene.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "4-7 days", + "zero": "7-10 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.2 mg" + }, + { + "name": "Light", + "value": "0.2 - 0.75 mg" + }, + { + "name": "Common", + "value": "0.75 - 1.75 mg" + }, + { + "name": "Strong", + "value": "1.75 - 3 mg" + }, + { + "name": "Heavy", + "value": "3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "14 - 24 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "2 - 4 hours" + }, + { + "name": "Peak", + "value": "6 - 10 hours" + }, + { + "name": "Offset", + "value": "4 - 8 hours" + }, + { + "name": "After effects", + "value": "4 - 16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 295, + "name": "DOC", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/DOC", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DOC.shtml", + "summary": "A potent stimulating psychedelic with a long action, a phenethylamine and substituted amphetamine. Sometimes sold as LSD but also enjoyed on its own merits by many. Usually sold on blotters slightly larger than those LSD is found on, but can also be bought in powder form.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 24 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "6 - 12 hours" + }, + { + "name": "Offset", + "value": "2 - 8 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.25 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 3.5 mg" + }, + { + "name": "Heavy", + "value": "3.5 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 8 hours" + }, + { + "name": "After effects", + "value": "2 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 296, + "name": "DOET", + "aliases": [ + "doe" + ], + "aliasesStr": "doe", + "url": "https://drugs.tripsit.me/doet", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DOET.shtml", + "summary": "A potent and long acting psychedelic stimulant and substituted amphetamine, similar in effects to other DOx compounds. First synthesised by Alexander Shulgin.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1mg" + }, + { + "name": "Light", + "value": "2-4mg" + }, + { + "name": "Common", + "value": "4-6mg" + }, + { + "name": "Strong", + "value": "6-10mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-3 hours" + }, + { + "name": "Duration", + "value": "12-30 hours" + }, + { + "name": "After effects", + "value": "12-72 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 297, + "name": "DOI", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/DOI", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DOI.shtml", + "summary": "A potent, long-acting psychedelic stimulant. Historically, it has rarely been consumed deliberately, but occasionally sold as LSD. However, it has recently found its own little nest in the research chemical community.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "10-14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 3 mg" + }, + { + "name": "Heavy", + "value": "3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "16 - 24 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "6 - 10 hours" + }, + { + "name": "Offset", + "value": "4 - 8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 298, + "name": "DOIP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/doip", + "experiencesUrl": null, + "summary": "A rare psychedelic ampthetamine of the same class as the likes of DOM. Is a quite powerful and potent psychedelic that has very strong amphetamine effects. Not for the faint of heart.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "800ug" + }, + { + "name": "Light", + "value": "800-1500ug" + }, + { + "name": "Common", + "value": "1.5-3mg" + }, + { + "name": "Strong", + "value": "3mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-120 minutes" + }, + { + "name": "Duration", + "value": "18-30 hours" + }, + { + "name": "After effects", + "value": "1-48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 299, + "name": "DOM", + "aliases": [ + "and peace)", + "stp", + "stp (serenity", + "tranquility" + ], + "aliasesStr": "and peace),stp,stp (serenity,tranquility", + "url": "https://psychonautwiki.org/wiki/DOM", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DOM.shtml", + "summary": "The most popular psychedelic amphetamine due to its pleasant effects, lower potency and shorter duration. Effects have been described as 'sillier' than LSD and related DOX chemicals", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 3 mg" + }, + { + "name": "Common", + "value": "3 - 5 mg" + }, + { + "name": "Strong", + "value": "5 - 10 mg" + }, + { + "name": "Heavy", + "value": "10 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 16 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "6 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "4 - 16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 300, + "name": "DON", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/don", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DON.shtml", + "summary": "A very rare psychedelic Amphetamine. That is more rough on the body then other DOx compounds. Making it physically painful in some cases.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "2mg" + }, + { + "name": "Light", + "value": "3mg" + }, + { + "name": "Common", + "value": "3-5mg" + }, + { + "name": "Heavy", + "value": "5mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "14-22 hours" + }, + { + "name": "After effects", + "value": "12-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 301, + "name": "DOPR", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/dopr", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DOPR.shtml", + "summary": "A rare psychedelic amphetamine of the same class as DOM. This is a powerful and potent psychedelic with all the effects you would expect from an amphetamine. Described by Shulgin as a 'heavy duty psychedelic'. Analogue of 2C-P.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1.25mg" + }, + { + "name": "Light", + "value": "2.5mg" + }, + { + "name": "Common", + "value": "2.5-3.5mg" + }, + { + "name": "Heavy", + "value": "3.5-5mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "90-240 minutes" + }, + { + "name": "Duration", + "value": "18-30 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 302, + "name": "Doxylamine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/doxylamine", + "experiencesUrl": null, + "summary": "A first generation antihistamine and anticholinergic, originally used to treat nausea and itching, and later as a sleep aid. Causes drowsiness, and delirium in overdose. Sometimes used with opioids to combat nausea and potentiate effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "6.25mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Heavy", + "value": "20-50mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-30 minutes" + }, + { + "name": "Duration", + "value": "6-8 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 303, + "name": "DPT", + "aliases": [ + "dipropyltryptamine", + "the light" + ], + "aliasesStr": "dipropyltryptamine,the light", + "url": "https://psychonautwiki.org/wiki/DPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_DPT.shtml", + "summary": "N,N-Dipropyltryptamine, a psychedelic tryptamine compound and lesser-known analogue of DMT, with similar psychedelic effects. Like DMT it is a partial serotonin receptor agonist.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "15 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 90 minutes" + }, + { + "name": "Onset", + "value": "0 - 1 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "75 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 350 mg" + }, + { + "name": "Heavy", + "value": "350 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "After effects", + "value": "2 - 3 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "20 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "Peak", + "value": "30 - 46 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "IM", + "dosage": [ + { + "name": "Threshold", + "value": "5-10mg" + }, + { + "name": "Light", + "value": "10-35mg" + }, + { + "name": "Common", + "value": "35-60mg" + }, + { + "name": "Strong", + "value": "60-100mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "2-10 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 304, + "name": "Dimenhydrinate", + "aliases": [ + "gravol" + ], + "aliasesStr": "gravol", + "url": "https://drugs.tripsit.me/dramamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Dimenhydrinate.shtml", + "summary": "A combination of diphenhydramine and a mild stimulant to counteract the drowsiness accompanied by typical medical use of diphenhydramine. Roughly half the potency of DPH. Small doses can relieve motion sickness, reduce body load from opioids or DXM. Becomes a deliriant in high doses, keeping the user awake and often causing dysphoric, realistic hallucinations.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "100-250mg" + }, + { + "name": "Common", + "value": "250mg-400mg" + }, + { + "name": "Strong", + "value": "400mg-600mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 305, + "name": "Efavirenz", + "aliases": [ + "sustiva" + ], + "aliasesStr": "sustiva", + "url": "https://psychonautwiki.org/wiki/Efavirenz", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Benzoxazine" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "low toxicity", + "may cause liver toxicity at high doses or after chronic use" + ], + "addictionPotential": "not known to be habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Common", + "value": "600 - 1800 mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ], + "bioavailability": "50%" + } + ], + "interactions": null + }, + { + "id": 306, + "name": "EFLEA", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/eflea", + "experiencesUrl": null, + "summary": "Prodrug for EDMA. May be inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 307, + "name": "Ephedrine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/ephedrine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ephedrine.shtml", + "summary": "Ephedrine is a sympathomimetic amine commonly used as a stimulant, concentration aid, decongestant, appetite suppressant, and to treat hypotension associated with anaesthesia. A methamphetamine analogue and commonly used in the production of methamphetamine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5-10mg" + }, + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-30mg" + }, + { + "name": "Strong", + "value": "30-50mg" + }, + { + "name": "Heavy", + "value": "50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "3 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 308, + "name": "Ephenidine", + "aliases": [ + "nedpa" + ], + "aliasesStr": "nedpa", + "url": "https://psychonautwiki.org/wiki/Ephenidine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ephenidine.shtml", + "summary": "A dissociative drug which is less potent and less confusing than MXE but with otherwise similar properties. Reported as causing light stimulant effects at lower doses.", + "reagents": null, + "classes": { + "chemical": [ + "Diarylethylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "30 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 309, + "name": "Ephylone", + "aliases": [ + "bk-ebdp", + "bk-ethyl-k", + "βk-ebdp" + ], + "aliasesStr": "bk-ebdp,bk-ethyl-k,βk-ebdp", + "url": "https://psychonautwiki.org/wiki/Ephylone", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": null, + "zero": null + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 80 mg" + }, + { + "name": "Heavy", + "value": null, + "note": "Ephylone may be fatal at heavy doses." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 310, + "name": "EPT", + "aliases": [ + "ethylpropyltryptamine", + "n,n-ethylpropyltryptamine" + ], + "aliasesStr": "ethylpropyltryptamine,n,n-ethylpropyltryptamine", + "url": "https://psychonautwiki.org/wiki/EPT", + "experiencesUrl": null, + "summary": "Ethylpropyltryptamine a novel tryptamine, that is the structural homologue of DMT.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "does not produce dependence and has low abuse potential", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 110 mg" + }, + { + "name": "Heavy", + "value": "110 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-75mg" + }, + { + "name": "Common", + "value": "75-100mg" + }, + { + "name": "Strong", + "value": "100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 311, + "name": "Escaline", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Escaline", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Escaline.shtml", + "summary": "First synthesised in the 50s, this uncommon drug was reexamined by David Nichols in the 1990s. It is an analogue of mescaline which is roughly six times more potent, and is thus a powerful psychedelic phenethylamine. Subjective effects may include stimulation and hallucinations.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "30 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "90 - 120 minutes" + }, + { + "name": "After effects", + "value": "3 - 5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 312, + "name": "Escitalopram", + "aliases": [ + "cipralex", + "lexapro" + ], + "aliasesStr": "cipralex,lexapro", + "url": "https://drugs.tripsit.me/escitalopram", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 313, + "name": "Estazolam", + "aliases": [ + "elprazolam", + "eurodin", + "prosom" + ], + "aliasesStr": "elprazolam,eurodin,prosom", + "url": "https://drugs.tripsit.me/estazolam", + "experiencesUrl": null, + "summary": "A rarely prescribed medium-duration prescription benzodiazepine. Mainly used as a hypnotic, it can cause amnesia and lowered inhibitions in excess.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "7-12 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ], + "bioavailability": "93%" + } + ], + "interactions": null + }, + { + "id": 314, + "name": "Eszopiclone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/eszopiclone", + "experiencesUrl": null, + "summary": "The d-isomer of Zopiclone, this drug is a potent hypnotic 'Z' drug often used to treat insomnia. High doses may cause amnesia, delirium and lowered inhibitions. Should not be combined with any depressants. Limited recreational value.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 315, + "name": "ETH-CAT", + "aliases": [ + "e-cat", + "ethcathinone", + "ethylcathinone", + "ethylpropion" + ], + "aliasesStr": "e-cat,ethcathinone,ethylcathinone,ethylpropion", + "url": "https://psychonautwiki.org/wiki/ETH-CAT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ethylcathinone.shtml", + "summary": "Ethylcathinone is a synthetic stimulant. It is similar to ecstasy in the sense that it provides euphoria, feelings of empathy and openness, and a desire to talk with others. It also carries over to some of the negative effects of ecstasy, such as insomnia, tightened jaw muscles, and grinding of the teeth.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "mildly addictive with a comparatively low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "2 - 3 days", + "zero": "3-5 days" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "60 mg" + }, + { + "name": "Light", + "value": "100 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 225 mg" + }, + { + "name": "Strong", + "value": "225 - 325 mg" + }, + { + "name": "Heavy", + "value": "325 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 40 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 120 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 35 mg" + }, + { + "name": "Common", + "value": "35 - 70 mg" + }, + { + "name": "Strong", + "value": "70 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "1 - 5 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 316, + "name": "ETH-LAD", + "aliases": [ + "ethlad" + ], + "aliasesStr": "ethlad", + "url": "https://psychonautwiki.org/wiki/ETH-LAD", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_ETHLAD.shtml", + "summary": "A psychedelic drug and slightly more potent analogue of LSD, first synthesised by Alexander Shulgin - sometimes described as being less 'abrasive' than LSD. Less common than the associated AL-LAD, though has seen some popularity since its release on the Internet research chemical scene in 2015.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 µg" + }, + { + "name": "Light", + "value": "30 - 60 µg" + }, + { + "name": "Common", + "value": "60 - 150 µg" + }, + { + "name": "Strong", + "value": "150 - 225 µg" + }, + { + "name": "Heavy", + "value": "225 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "8 - 48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 317, + "name": "Ethaqualone", + "aliases": [ + "etaqualone" + ], + "aliasesStr": "etaqualone", + "url": "https://drugs.tripsit.me/ethaqualone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Etaqualone.shtml", + "summary": "Analogue of Methaqualone that was mostly marketed in France. Slightly weaker and shorter acting than the prior.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "100-175mg" + }, + { + "name": "Common", + "value": "175-300mg" + }, + { + "name": "Strong", + "value": "300-450mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "2-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 318, + "name": "Ethketamine", + "aliases": [ + "n-ethyl-norketamine", + "n-ethylnorketamine", + "nek" + ], + "aliasesStr": "n-ethyl-norketamine,n-ethylnorketamine,nek", + "url": "https://drugs.tripsit.me/ethketamine", + "experiencesUrl": null, + "summary": "Ethketamine is a research chemical with properties similar to ketamine. While ketamine is a dissociative anesthetic producing hallucinogenic and sedative effects, recreational users have reported euphoria and dissociation when using NENK.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "15-40mg" + }, + { + "name": "Common", + "value": "40-90mg" + }, + { + "name": "Strong", + "value": "90-160mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 319, + "name": "NEP", + "aliases": [ + "ethyl-pentedrone", + "n-ethylpentedrone" + ], + "aliasesStr": "ethyl-pentedrone,n-ethylpentedrone", + "url": "https://psychonautwiki.org/wiki/NEP", + "experiencesUrl": null, + "summary": "A stimulant that came out around the same time as Ethyl-Hexedrone, not much information on it. Is in the cathinone family of substances. Related to Pentedrone.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 3 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 320, + "name": "Ethylmorphine", + "aliases": [ + "codethyline", + "dionine" + ], + "aliasesStr": "codethyline,dionine", + "url": "https://psychonautwiki.org/wiki/Ethylmorphine", + "experiencesUrl": null, + "summary": "A medium-strength opioid analgesic and analogue of morphine. Considered less potent than morphine but more potent than codeine, and has been used in Germany for this reason. Said to have a 'ceiling' effect where no more euphoria occurs with increased dosage. Under investigation as a maintainance drug in opioid dependence therapy.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "very addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 5 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 321, + "name": "Ethylone", + "aliases": [ + "bk-mdea", + "mdec" + ], + "aliasesStr": "bk-mdea,mdec", + "url": "https://psychonautwiki.org/wiki/Ethylone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_bkMDEA.shtml", + "summary": "A euphoric stimulant often sold in place of MDMA since methylone was banned. Slightly less potent and empathogenic than methylone, it is often described as more of a 'straight stimulant.'", + "reagents": null, + "classes": { + "chemical": null, + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 mg" + }, + { + "name": "Light", + "value": "75 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 225 mg" + }, + { + "name": "Strong", + "value": "225 - 325 mg" + }, + { + "name": "Heavy", + "value": "325 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 120 minutes" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 322, + "name": "Ethylphenidate", + "aliases": [ + "eph" + ], + "aliasesStr": "eph", + "url": "https://psychonautwiki.org/wiki/Ethylphenidate", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ethylphenidate.shtml", + "summary": "Potent psychostimulant, similar to Methylphenidate. \u0002Note: Ethylphenidate should \u0016NOT\u0016 be insufflated as it is known to be highly caustic and will cause serious harm to your nasal septum, even with light usage.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopaminergic", + "stimulants" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 120 mg" + }, + { + "name": "Heavy", + "value": "120 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "40 - 120 minutes" + } + ] + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + } + ] + }, + { + "name": "Plugged/Rectal", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-50mg" + }, + { + "name": "Heavy", + "value": "50-75mg" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "1-10 minutes" + }, + { + "name": "Duration", + "value": "2-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Plugged", + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "2-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 323, + "name": "Etizolam", + "aliases": [ + "depas", + "etilaam", + "etiz", + "etizest", + "etizola", + "inxity", + "lamet", + "sedekopan", + "towa", + "zoly" + ], + "aliasesStr": "depas,etilaam,etiz,etizest,etizola,inxity,lamet,sedekopan,towa,zoly", + "url": "https://psychonautwiki.org/wiki/Etizolam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Etizolam.shtml", + "summary": "A thienodiazepine anxiolytic. Similar in action to benzodiazepine drugs. Relieves anxiety, causes sedation and mild euphoria. High doses can lead to losing memory of what happened while on the drug. Users often compulsively re-dose frequently leading to accidental blackouts. Can be found in pressed pharmaceutical pills from various countries, clandestine pill presses, or as a powder", + "reagents": null, + "classes": { + "chemical": [ + "Thienodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "highly addictive with a high potential for abuse", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepine", + "thienodiazepine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.2 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2.5 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ], + "bioavailability": "93%" + } + ], + "interactions": null + }, + { + "id": 324, + "name": "Etodesnitazene", + "aliases": [ + "etazene" + ], + "aliasesStr": "etazene", + "url": "https://drugs.tripsit.me/etodesnitazene", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 325, + "name": "F-Phenibut", + "aliases": [ + "fluorobut", + "fluorophenibut" + ], + "aliasesStr": "fluorobut,fluorophenibut", + "url": "https://psychonautwiki.org/wiki/F-Phenibut", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Gabapentinoids" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids", + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "GABA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 600 mg" + }, + { + "name": "Heavy", + "value": "600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 326, + "name": "Fasoracetam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/fasoracetam", + "experiencesUrl": null, + "summary": "A substance in the racetam family. Appears to be a GABA(B) agonist, and has shown to block memory disruptions caused by Baclofen, another GABA(B) Agonist. Similar to another compound in the racetam family Coluracetam, it enhances High affinity choline reuptake (HACU). Also research is conducted if it helps with ADHD and Congitive impairment.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-25mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 327, + "name": "Fentanyl", + "aliases": [ + "abstral", + "actiq", + "duragesic", + "durogesic", + "fent", + "fentanil", + "fentora", + "haldid", + "instanyl", + "lazanda", + "matrifen", + "onsolis", + "sublimaze" + ], + "aliasesStr": "abstral,actiq,duragesic,durogesic,fent,fentanil,fentora,haldid,instanyl,lazanda,matrifen,onsolis,sublimaze", + "url": "https://psychonautwiki.org/wiki/Fentanyl", + "experiencesUrl": null, + "summary": "Fentanyl is a synthetic opiate analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors and is historically used to treat breakthrough pain. Fentanyl is approximately 100 times more potent than Morphine, and is commonly used as a patch. Sometimes used as an adulterant for heroin, which has led to many overdose deaths.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_piperidines", + "Anilidopiperidine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "unintentionally transporting the substance from the skin by touching the mouth, nose or eyes is dangerous" + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "5 - 10 μg" + }, + { + "name": "Light", + "value": "10 - 25 μg" + }, + { + "name": "Common", + "value": "25 - 50 μg" + }, + { + "name": "Strong", + "value": "50 - 75 μg" + }, + { + "name": "Heavy", + "value": "75 μg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + } + ], + "bioavailability": "50%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 - 10 μg" + }, + { + "name": "Light", + "value": "10 - 25 μg" + }, + { + "name": "Common", + "value": "25 - 50 μg" + }, + { + "name": "Strong", + "value": "50 - 75 μg" + }, + { + "name": "Heavy", + "value": "75 μg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + } + ], + "bioavailability": "89%" + }, + { + "name": "Transdermal", + "dosage": [ + { + "name": "Threshold", + "value": "5 - 12 μg" + }, + { + "name": "Light", + "value": "12 - 25 μg" + }, + { + "name": "Common", + "value": "25 - 50 μg" + }, + { + "name": "Strong", + "value": "50 - 100 μg" + }, + { + "name": "Heavy", + "value": "100 μg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "48 - 72 hours" + }, + { + "name": "Onset", + "value": "2 - 4 hours" + } + ], + "bioavailability": "92%" + }, + { + "name": "Intranasal", + "dosage": [ + { + "name": "Light", + "value": "10-25ug" + }, + { + "name": "Common", + "value": "25-50ug" + }, + { + "name": "Strong", + "value": "50-75ug+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "Risk" + } + ] + }, + { + "name": "Buccal", + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "1-4 hours" + }, + { + "name": "After effects", + "value": "Risk" + } + ] + } + ], + "interactions": null + }, + { + "id": 328, + "name": "Flualprazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/flualprazolam", + "experiencesUrl": null, + "summary": "Fluorinated alprazolam, that likely has a longer half-life and higher potency than its parent compound.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.125-0.25mg" + }, + { + "name": "Common", + "value": "0.25-0.5mg" + }, + { + "name": "Strong", + "value": "0.5-1mg" + }, + { + "name": "Heavy", + "value": "1-2mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "6-14 hours" + }, + { + "name": "After effects", + "value": "1-36 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 329, + "name": "Flubromazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Flubromazepam", + "experiencesUrl": null, + "summary": "A somewhat common benzodiazepine drug known for its extreme duration, with effects for larger doses reaching up to three days. Sedative, hypnotic and anxiolytic, this compound is an analogue of Phenazepam. First discovered in the 1960s, it was never marketed as a licit drug, but has recently become available as an RC. Not to be confused with Flubromazolam.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 - 16 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "40 - 90 minutes" + }, + { + "name": "After effects", + "value": "24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 330, + "name": "Flubromazolam", + "aliases": [ + "f-lam", + "flam" + ], + "aliasesStr": "f-lam,flam", + "url": "https://psychonautwiki.org/wiki/Flubromazolam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Flubromazolam.shtml", + "summary": "A very potent benzodiazepine derivative that is related to Triazolam and Pyrazolam. Popular in the research chemical scene, it is a potent sedative, hypnotic and anxiolytic. Potential for amnesia and reduced inhibitions in higher dose. Not to be confused with Flubromazepam, which is much less potent and has a much longer half-life.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 μg" + }, + { + "name": "Light", + "value": "100 - 150 μg" + }, + { + "name": "Common", + "value": "150 - 250 μg" + }, + { + "name": "Strong", + "value": "250 - 400 μg" + }, + { + "name": "Heavy", + "value": "400 μg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 18 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "24 hours +" + } + ] + } + ], + "interactions": null + }, + { + "id": 331, + "name": "Fluclotizolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/fluclotizolam", + "experiencesUrl": null, + "summary": "A derivative of Etizolam. There are conflicting reports on its dosage, though claims have been made that it is approximately 3x the potency of Etizolam, with a shorter half-life.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "250ug" + }, + { + "name": "Common", + "value": "250-500ug" + }, + { + "name": "Strong", + "value": "500-750ug" + }, + { + "name": "Heavy", + "value": "750ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-14 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 332, + "name": "Flunitrazepam", + "aliases": [ + "rohypnol", + "roofies" + ], + "aliasesStr": "rohypnol,roofies", + "url": "https://drugs.tripsit.me/flunitrazepam", + "experiencesUrl": null, + "summary": "Known as Rohypnol or 'roofies,' this infamous drug has similar qualities to most other benzodiazepines; sedating with strong hypnotic effects. Despite being known as a 'date rape drug' has only been implicated in a small number of such crimes. Danger of respiratory depression in combination with other depressants. May cause amnesia and lowered inhibitions in overdose.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Heavy", + "value": "2-4mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 333, + "name": "Flunitrazolam", + "aliases": [ + "fln" + ], + "aliasesStr": "fln", + "url": "https://drugs.tripsit.me/flunitrazolam", + "experiencesUrl": null, + "summary": "A very potent hypnotic Benzodiazepine. Triazolo version of Flunitrazepam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30-40ug" + }, + { + "name": "Light", + "value": "40-80ug" + }, + { + "name": "Common", + "value": "80-150ug" + }, + { + "name": "Strong", + "value": "150-300ug." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-5 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + }, + { + "name": "Sublingual", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "4-5 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 334, + "name": "Fluorolintane", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/fluorolintane", + "experiencesUrl": null, + "summary": "A dissociative anaesthetic also known as 2-FPPP, very little is known about this obscure and rare drug. Reported by some to be stimulating, having effects similar to other dissociative drugs such as PCP and ketamine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "75-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "150-250mg" + }, + { + "name": "Heavy", + "value": "250mg+." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "2-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 335, + "name": "Fluorophenibut", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/fluorophenibut", + "experiencesUrl": null, + "summary": "An anxiolytic analogue of GABA and Phenibut, with similar activity to the latter. Expected to be 5-10 times as potent as phenibut, some preliminary reports suggest tolerance builds more slowly.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "200-250mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-120 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 336, + "name": "Fluoxetine", + "aliases": [ + "prozac", + "sarafem" + ], + "aliasesStr": "prozac,sarafem", + "url": "https://drugs.tripsit.me/fluoxetine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 337, + "name": "Flurazepam", + "aliases": [ + "dalmane" + ], + "aliasesStr": "dalmane", + "url": "https://drugs.tripsit.me/flurazepam", + "experiencesUrl": null, + "summary": "Benzodiazepine with an extremely long half life, between 40 and 250 hours. Mainly used for general anxiety disorder. Sedating, hypnotic, anxiolytic. Potential for amnesia and reduced inhibitions in overdose.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-60mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "12-16 hours" + }, + { + "name": "After effects", + "value": "2-48 hours" + } + ], + "bioavailability": "83%" + } + ], + "interactions": null + }, + { + "id": 338, + "name": "Flutazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/flutazolam", + "experiencesUrl": null, + "summary": "A benzodiazepine derivative. It was invented in Japan, and has mainly stayed in that area. Similar potency to Diazepam, yet produces a more marked sedation and impaired coordination. Usually used as a treatment for Insomnia. A hypnotic and sedative which may cause amnesia and lowered inhibitions in high doses.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 339, + "name": "Flutoprazepam", + "aliases": [ + "restas" + ], + "aliasesStr": "restas", + "url": "https://drugs.tripsit.me/flutoprazepam", + "experiencesUrl": null, + "summary": "A potent benzodiazepine that is roughly 4-5x the potency of Diazepam and has a longer duration, rarely seen outside of Japan. Sedative, hypnotic and anxiolytic. May cause amnesia and loss of inhibitions in excess. Do not mix with other depressants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1.5-3mg" + }, + { + "name": "Strong", + "value": "3-5mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "12-16 hours" + }, + { + "name": "After effects", + "value": "24-36 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 340, + "name": "Fluvoxamine", + "aliases": [ + "faverin", + "luvox" + ], + "aliasesStr": "faverin,luvox", + "url": "https://drugs.tripsit.me/fluvoxamine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 341, + "name": "Dexmethylphenidate", + "aliases": [ + "dextromethylphenidate" + ], + "aliasesStr": "dextromethylphenidate", + "url": "https://drugs.tripsit.me/focalin", + "experiencesUrl": null, + "summary": "The psychoactive isomer of methylphenidate, mostly used to treat ADHD. Twice as potent as methylphenidate, and is said to have cleaner psychostimulant effects with fewer side effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-30mg" + }, + { + "name": "Strong", + "value": "30-40mg" + }, + { + "name": "Heavy", + "value": "40-50mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90" + }, + { + "name": "Duration", + "value": "9-12 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 342, + "name": "Furanylfentanyl", + "aliases": [ + "fu-f", + "furanyl-fentanyl" + ], + "aliasesStr": "fu-f,furanyl-fentanyl", + "url": "https://drugs.tripsit.me/furanylfentanyl", + "experiencesUrl": null, + "summary": "An extremely potent opioid analgesic and analogue of fentanyl. Concrete information is difficult to obtain about even basic properties like active dose, though it is believed to be slightly less potent and shorter in duration than butyrfentanyl. Exercise extreme caution. Will cause respiratory depression in overdose.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "300-500ug" + }, + { + "name": "Common", + "value": "500-900ug" + }, + { + "name": "Strong", + "value": "900-1600ug+." + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-10 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "200-400ug" + }, + { + "name": "Common", + "value": "400-800ug" + }, + { + "name": "Strong", + "value": "800-1600ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-10 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 343, + "name": "G-130", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/g-130", + "experiencesUrl": null, + "summary": "Stimulant that is related to Phenmetrazine. Nearly no information on dose or effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 344, + "name": "GABA", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/gaba", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_GABA.shtml", + "summary": "Gamma-Aminobutyric Acid. Supplement used in calming some down. Does not pass the brain blood barrier.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "200-400mg" + }, + { + "name": "Common", + "value": "400-800mg" + }, + { + "name": "Strong", + "value": "800-1600mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-60 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 345, + "name": "Gabapentin", + "aliases": [ + "gabarone", + "gralise", + "neurontin" + ], + "aliasesStr": "gabarone,gralise,neurontin", + "url": "https://psychonautwiki.org/wiki/Gabapentin", + "experiencesUrl": null, + "summary": "An analogue of GABA also known as Neurontin, originally developed to treat epilepsy. Commonly prescribed for neuropathic pain, it also has pronounced anxiolytic effects leading to its use in treating anxiety disorders.", + "reagents": null, + "classes": { + "chemical": [ + "Gabapentinoids" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": null, + "tolerance": { + "full": "with prolonged continuous usage", + "half": null, + "zero": "7-14 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "200 mg" + }, + { + "name": "Light", + "value": "200 - 600 mg" + }, + { + "name": "Common", + "value": "600 - 900 mg" + }, + { + "name": "Strong", + "value": "900 - 1200 mg" + }, + { + "name": "Heavy", + "value": "1200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ], + "bioavailability": "27% - 60%" + } + ], + "interactions": null + }, + { + "id": 346, + "name": "Galantamine", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Galantamine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Benzazepine" + ], + "psychoactive": [ + "Sedative", + "Oneirogen" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 16 mg" + }, + { + "name": "Strong", + "value": "16 - 24 mg" + }, + { + "name": "Heavy", + "value": "24 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + } + ], + "bioavailability": "90%" + } + ], + "interactions": null + }, + { + "id": 347, + "name": "GBL", + "aliases": [ + "gamma-butyrolactone" + ], + "aliasesStr": "gamma-butyrolactone", + "url": "https://psychonautwiki.org/wiki/GBL", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_GBL.shtml", + "summary": "A pro-drug to GHB whose rapid absorption leads it to have a faster onset and shorter duration. Used in a similar manner to GHB, as a less-toxic alternative to alcohol. Consume slowly instead of as a \"shot\" to hugely improve safety and reduce overdose risk.", + "reagents": null, + "classes": { + "chemical": [ + "Tetrahydrofuran" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": null, + "addictionPotential": "highly physically and moderately to highly psychologically addictive", + "tolerance": { + "full": "within several days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.3 ml" + }, + { + "name": "Light", + "value": "0.3 - 0.9 ml" + }, + { + "name": "Common", + "value": "0.9 - 1.5 ml" + }, + { + "name": "Strong", + "value": "1.5 - 3 ml", + "note": "Warning: Doses over 2 ml can induce heavy sleep." + }, + { + "name": "Heavy", + "value": "3+ ml" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "3 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 15 minutes" + }, + { + "name": "Peak", + "value": "30 - 45 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 348, + "name": "GHB", + "aliases": [ + "g", + "sodium oxybate", + "xyrem" + ], + "aliasesStr": "g,sodium oxybate,xyrem", + "url": "https://psychonautwiki.org/wiki/GHB", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_GHB.shtml", + "summary": "A euphoric depressant which is prescribed as a sleep aid and sometimes to help with Alcohol detox. Also used as a recreational depressant, as a non-toxic alternative to Alcohol. Despite not having Alcohol's toxicity it is risky due to among other things inconsistent concentration in commonly sold solution form, and can be very dangerous if taken with other depressants.", + "reagents": null, + "classes": { + "chemical": [ + "Butyric_acid" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "Doses above 10 grams are associated with a risk of death", + "considered to be a safe and non-toxic substance when used responsibly or medically" + ], + "addictionPotential": "moderately to highly physically and moderately psychologically addictive", + "tolerance": { + "full": "within several days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 g" + }, + { + "name": "Light", + "value": "0.5 - 1 g" + }, + { + "name": "Common", + "value": "1 - 2.5 g" + }, + { + "name": "Strong", + "value": "2.5 - 4 g" + }, + { + "name": "Heavy", + "value": "4 g +", + "note": "Warning: Risk of death above 10 g" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Come up", + "value": "10 - 20 minutes" + }, + { + "name": "Peak", + "value": "45 - 90 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 349, + "name": "Glaucine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/glaucine", + "experiencesUrl": null, + "summary": "An alkaloid that is found in several different scpecies in the Papaveraceae family. It has antiinflammatory and antitussive effects. Can also be referred to as Yellow Horned Poppy.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100mg" + }, + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "150-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "6-8 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 350, + "name": "Glutethimide", + "aliases": [ + "doriden", + "elrodorm", + "glimid", + "noxyron" + ], + "aliasesStr": "doriden,elrodorm,glimid,noxyron", + "url": "https://drugs.tripsit.me/glutethimide", + "experiencesUrl": null, + "summary": "Is a hypnotic sedative that was introduced in 1954, as a \"safe\" alternative to barbiturates to treat insomnia. Anecdotally long term use has had effects similar to withdrawal, while still on a stable dose of the drug.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "250mg" + }, + { + "name": "Common", + "value": "500mg" + }, + { + "name": "Strong", + "value": "750mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "2-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 351, + "name": "Halazepam", + "aliases": [ + "paxipam" + ], + "aliasesStr": "paxipam", + "url": "https://drugs.tripsit.me/halazepam", + "experiencesUrl": null, + "summary": "A less common prescription benzodiazepine and derivative of Nordazepam. Also known as Paxipam, it is no longer prescribed in the USA. Sedating, hypnotic and anxiolytic. High doses may induce amnesia and lowered inhibitions.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Strong", + "value": "40-80mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "8-14 hours" + }, + { + "name": "After effects", + "value": "12-40 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 352, + "name": "Haloperidol", + "aliases": [ + "haldol" + ], + "aliasesStr": "haldol", + "url": "https://psychonautwiki.org/wiki/Haloperidol", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Butyrophenone", + "Substituted_piperidines" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "toxicity": [ + "can have serious side effects at higher dosages", + "risk of having severe extrapyramidal symptoms and muscle rigidity" + ], + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.25 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 5 mg" + }, + { + "name": "Strong", + "value": "5 - 10 mg" + }, + { + "name": "Heavy", + "value": "10 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 36 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ], + "bioavailability": "60-70%" + } + ], + "interactions": null + }, + { + "id": 353, + "name": "Halothane", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/halothane", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Halothane.shtml", + "summary": "A powerful inhalant anaesthetic generally used in a medical setting to induce unconsciousness, as a supplement with ketamine or fentanyl.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 354, + "name": "HDEP-28", + "aliases": [ + "ethylnaphthidate" + ], + "aliasesStr": "ethylnaphthidate", + "url": "https://drugs.tripsit.me/hdep-28", + "experiencesUrl": null, + "summary": "Most likely a TRI, such as HDMP-28, short history of human use.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "15-30mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Strong", + "value": "50-100mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-15 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-35mg" + }, + { + "name": "Strong", + "value": "35-60mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-15 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 355, + "name": "HDMP-28", + "aliases": [ + "methylnaphthidate", + "methylnaphtidate" + ], + "aliasesStr": "methylnaphthidate,methylnaphtidate", + "url": "https://psychonautwiki.org/wiki/Methylnaphthidate", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_HDMP28.shtml", + "summary": "Also commonly known as methylnapthidate. A functional stimulant similar to methylphenidate but with a longer duration. Not especially recreational.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "4 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "1 - 10 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "< 4 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 14 mg" + }, + { + "name": "Strong", + "value": "14 - 28 mg" + }, + { + "name": "Heavy", + "value": "28 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "90 - 180 minutes" + }, + { + "name": "Onset", + "value": "3 - 6 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 356, + "name": "Heroin", + "aliases": [ + "brown", + "diamorphine", + "h", + "junk", + "smack" + ], + "aliasesStr": "brown,diamorphine,h,junk,smack", + "url": "https://psychonautwiki.org/wiki/Heroin", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Heroin.shtml", + "summary": "A powerful opioid derived from Morphine, with 2-4x its potency. Infamous for a high addiction potential and fatal respiratory depression in overdose, C. R. Alder Wright first synthesised this compound in 1874 trying to find a less addictive alternative to Morphine. In recent years, it has often been sold cut with the extremely potent fentanyl, causing a spike in overdose deaths.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 10 seconds" + }, + { + "name": "Come up", + "value": "5 - 10 seconds" + }, + { + "name": "Peak", + "value": "15 - 30 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "10 - 30 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "7.5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 7 hours" + }, + { + "name": "Onset", + "value": "10 - 60 seconds" + }, + { + "name": "Come up", + "value": "10 - 60 seconds" + }, + { + "name": "Peak", + "value": "1 - 90 minutes" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "1.5 - 3 hours" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Common", + "value": "5 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 5 hours" + }, + { + "name": "Onset", + "value": "0 - 5 seconds" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "Offset", + "value": "-" + } + ] + } + ], + "interactions": null + }, + { + "id": 357, + "name": "Hexedrone", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Hexedrone", + "experiencesUrl": null, + "summary": "A rare mephedrone analogue also known as MACP, a cathinone stimulant with similar effects to pentedrone.", + "reagents": null, + "classes": { + "chemical": null, + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "50 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 125 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "1 - 12 hours" + } + ] + }, + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "30-50mg" + }, + { + "name": "Light", + "value": "50-70mg" + }, + { + "name": "Common", + "value": "70-100mg" + }, + { + "name": "Strong", + "value": "100-125mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "1-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 358, + "name": "Hexen", + "aliases": [ + "ethyl-hexedrone", + "hex-en", + "n-ethyl-hexedrone", + "n-ethylhexedrone", + "neh" + ], + "aliasesStr": "ethyl-hexedrone,hex-en,n-ethyl-hexedrone,n-ethylhexedrone,neh", + "url": "https://psychonautwiki.org/wiki/N-Ethylhexedrone", + "experiencesUrl": null, + "summary": "A cathinone based stimulant. Hexen (aka Ethyl-Hexedrone) acts as an NDRI to produce it's effects, and as with most cathinones has a fast onset and short duration. This drug has very little history of human consumption and next to no research/data, and therefor should be treated with caution as a research chemical.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "norepinephrine|noradrenergic", + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 10 minutes" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "15 - 30 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 8 minutes" + }, + { + "name": "Peak", + "value": "30 - 90 minutes" + }, + { + "name": "Offset", + "value": "1 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5-15mg" + }, + { + "name": "Light", + "value": "15-25mg" + }, + { + "name": "Common", + "value": "25-40mg" + }, + { + "name": "Strong", + "value": "40-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "1-4 hours" + }, + { + "name": "After effects", + "value": "2-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 359, + "name": "Hexobarbital", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/hexobarbital", + "experiencesUrl": null, + "summary": "Is a barbiturate that was once used for inducing anesthesia for surgery. It has a very rapid onset, and a short duration of effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "10-15mg" + }, + { + "name": "Common", + "value": "15-20mg" + }, + { + "name": "Strong", + "value": "20-30mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "30-45 minutes" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 360, + "name": "Homomazindol", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/homomazindol", + "experiencesUrl": null, + "summary": "A potent analogue of mazindol, a rare, atypical stimulant drug and appetite suppressant occasionally prescribed in cases of severe obesity.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 361, + "name": "Homosildenafil", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/homosildenafil", + "experiencesUrl": null, + "summary": "An analogue of sildenafil (viagra) with similar effects. Has been missold in certain 'herbal' blends and dietary supplements for sexual potency. Little is known about the pharmacology or safety profile of this drug in humans, potentially less potent than sildenafil.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50-100mg" + } + ], + "duration": [ + { + "name": "Duration", + "value": "5-9 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 362, + "name": "HOT-2", + "aliases": [ + "hot2" + ], + "aliasesStr": "hot2", + "url": "https://drugs.tripsit.me/hot-2", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_HOT2.shtml", + "summary": "A rather rare psychedelic phenylethylamine that is the hydroxylated version and prodrug for 2C-T-2.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "8mg" + }, + { + "name": "Light", + "value": "10-12mg" + }, + { + "name": "Common", + "value": "12-15mg" + }, + { + "name": "Strong", + "value": "15-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "5-12 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 363, + "name": "HOT-7", + "aliases": [ + "hot7" + ], + "aliasesStr": "hot7", + "url": "https://drugs.tripsit.me/hot-7", + "experiencesUrl": null, + "summary": "A rather rare psychedelic phenylethylamine that is the hydroxylated version and prodrug for 2C-T-7.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15mg" + }, + { + "name": "Light", + "value": "15-20mg" + }, + { + "name": "Common", + "value": "20-30mg" + }, + { + "name": "Strong", + "value": "30-40mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-180 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 364, + "name": "HUPERZINE-A", + "aliases": [ + "h-a" + ], + "aliasesStr": "h-a", + "url": "https://drugs.tripsit.me/huperzine-a", + "experiencesUrl": null, + "summary": "A compound that is extracted from the herbs of Huperziceae family. Is known as an acetylcholinesterase inhibitor, which stops an enzyme from breaking down acetylcholine which results in increases in acetylcholine. Is currently in preliminary trials for Alzheimer's.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflted", + "dosage": [ + { + "name": "Light", + "value": "50-75ug" + }, + { + "name": "Common", + "value": "75-150ug" + }, + { + "name": "Strong", + "value": "150ug-200ug." + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-14 hours" + } + ] + }, + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "8-14 hours" + }, + { + "name": "After effects", + "value": "1-14 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-14 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 365, + "name": "Hydrocodone", + "aliases": [ + "hydro", + "vicodin", + "vicodin (with paracetamol)", + "zohydro er (extended-release)" + ], + "aliasesStr": "hydro,vicodin,vicodin (with paracetamol),zohydro er (extended-release)", + "url": "https://psychonautwiki.org/wiki/Hydrocodone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Hydrocodone.shtml", + "summary": "A codeine-derived opioid generally unheard of outside the United States. Generally mild in effects, used as an analgesic and cough-supressant. Sometimes used recreationally.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages" + ], + "addictionPotential": "moderately addictive", + "tolerance": { + "full": "with prolonged use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "10 - 60 minutes" + } + ], + "bioavailability": "70-85%" + } + ], + "interactions": null + }, + { + "id": 366, + "name": "Hydromorphone", + "aliases": [ + "dilaudid", + "diluadid", + "jurnista", + "palladone" + ], + "aliasesStr": "dilaudid,diluadid,jurnista,palladone", + "url": "https://psychonautwiki.org/wiki/Hydromorphone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Hydromorphone.shtml", + "summary": "An opioid that is roughly 5x the potency of IV Morphine. Only comes in IR tablets in the US, and is given mostly as XR in other countries. It is frequently used in hospitals for short, but immediate pain relief during procedures requiring the patient to be awake. Also frequently used as a recreational opiate.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 8 mg" + }, + { + "name": "Heavy", + "value": "8 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + } + ], + "bioavailability": "51.35% +/- 29.29%" + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10 - 90 seconds" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "1-2mg" + }, + { + "name": "Common", + "value": "3-4mg" + }, + { + "name": "Strong", + "value": "4-8mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ], + "bioavailability": "52.4%" + } + ], + "interactions": null + }, + { + "id": 367, + "name": "Hydroxyzine", + "aliases": [ + "atarax", + "vistaril" + ], + "aliasesStr": "atarax,vistaril", + "url": "https://drugs.tripsit.me/hydroxyzine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Hydroxyzine.shtml", + "summary": "An antihistamine drug commonly prescribed for anxiety, itchiness, nausea, and insomnia. Hydroxyzine has also been used to potentiate the analgesia of opioids as well as diminishing the negative effects of opioids, such as itchiness.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "25-100mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 368, + "name": "Hyoscyamus niger (botany)", + "aliases": [ + "henbane", + "stinking nightshade" + ], + "aliasesStr": "henbane,stinking nightshade", + "url": "https://psychonautwiki.org/wiki/Hyoscyamus_niger_(botany)", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 369, + "name": "Ibogaine", + "aliases": [ + "iboga" + ], + "aliasesStr": "iboga", + "url": "https://psychonautwiki.org/wiki/Ibogaine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ibogaine.shtml", + "summary": "An alkaloid found in many African plants most famously Iboga, with psychedelic and hallucinogenic properties. May be unpleasant. Traditionally used in tribal environments for coming-of-age rituals, it has recently been used as an alternative treatment for drug addiction although this usage has not been backed by conclusive data in humans. Has killed in overdose.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "15 - 22 mg/kg of body weight" + }, + { + "name": "Strong", + "value": null, + "note": "Strong doses may result in fatal heart complications." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30 - 180 minutes" + }, + { + "name": "Peak", + "value": "18 - 36 hours" + }, + { + "name": "After effects", + "value": "24 - 72 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 370, + "name": "Ibuprofen", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/ibuprofen", + "experiencesUrl": null, + "summary": "A ubiquitously available pain reliever/fever reducer. Ibuprofen is a nonsteroidal anti-inflammatory drug, available in many forms. It is sometimes used to reduce the body-load caused by certain drugs, such as stimulants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "400-800mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "within" + }, + { + "name": "Duration", + "value": "4-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 371, + "name": "Indapex", + "aliases": [ + "5-meo-tmt" + ], + "aliasesStr": "5-meo-tmt", + "url": "https://drugs.tripsit.me/indapex", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_5MeOTMT.shtml", + "summary": "5-MEO-TMT, one of Shulgin's lesser known creations. A psychedelic tryptamine little heard of outside of TiHKaL with very little known information about its effects on humans. May be particularly given to causing nausea.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "60-75mg" + }, + { + "name": "Common", + "value": "75-100mg" + }, + { + "name": "Strong", + "value": "100-150mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-50 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 372, + "name": "Indapyrophenidone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/indapyrophenidone", + "experiencesUrl": null, + "summary": "Indane analogue of Pyrophenidone, a NDRI stimulant with a short duration.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Vaporized", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-25mg" + }, + { + "name": "Strong", + "value": "25-50mg" + }, + { + "name": "Heavy", + "value": "50mg+." + } + ], + "duration": [ + { + "name": "Duration", + "value": "1-1.5 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60-90mg" + }, + { + "name": "Heavy", + "value": "90mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 373, + "name": "Isomethadone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/isomethadone", + "experiencesUrl": null, + "summary": "Once a pharmaceutical drug also known as isoamidone, this opioid analgesic and methadone analogue was withdrawn from the market and is seldom seen today. Rarely abused, though reports state it is around twice as potent as methadone, and more euphoric.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "1.5-2.5mg" + }, + { + "name": "Common", + "value": "2.5-7.5mg" + }, + { + "name": "Strong", + "value": "7.5-15mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "30-40 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 374, + "name": "Isophenmetrazine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/isophenmetrazine", + "experiencesUrl": null, + "summary": "Rare and little known analogue of phenmetrazine, which is slightly more potent than other analogues. Probably a stimulating, appetite supressing drug with high addiction potential. Potentially a dopamine and/or norepinephrine releasing agent.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-15mg" + }, + { + "name": "Strong", + "value": "20-40mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 375, + "name": "Isopropylphenidate", + "aliases": [ + "iph", + "ipp", + "ippd", + "ipph" + ], + "aliasesStr": "iph,ipp,ippd,ipph", + "url": "https://psychonautwiki.org/wiki/Isopropylphenidate", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Isopropylphenidate.shtml", + "summary": "IPPH (or incorrectly IPH) is a novel piperidine based methylphenidate analogue and NDRI stimulant, but comes with much less physical side effects.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 45 mg" + }, + { + "name": "Heavy", + "value": "45 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3.5 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "Come up", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 376, + "name": "Isoproscaline", + "aliases": [ + "ip" + ], + "aliasesStr": "ip", + "url": "https://drugs.tripsit.me/isoproscaline", + "experiencesUrl": null, + "summary": "A analogue of mescaline, and more closely related to proscaline.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30mg" + }, + { + "name": "Light", + "value": "40-50mg" + }, + { + "name": "Common", + "value": "50-60mg" + }, + { + "name": "Strong", + "value": "60-80mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-180 minutes" + }, + { + "name": "Duration", + "value": "10-20 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 377, + "name": "Jenkem", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/jenkem", + "experiencesUrl": null, + "summary": "A hoax which began in online communities of a non-existent drug which was claimed to result from a process involving human waste. http://www.snopes.com/crime/warnings/jenkem.asp", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 378, + "name": "JWH-073", + "aliases": [ + "spice" + ], + "aliasesStr": "spice", + "url": "https://psychonautwiki.org/wiki/JWH-073", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Naphthoylindole" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "cannabinoids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 3 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "60 - 90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 379, + "name": "Kanna", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/kanna", + "experiencesUrl": null, + "summary": "A South African plant containing numerous psychoactive alkaloids, including mesembrine and mesembrenone. The first written account of the substance was in 1662. The pharmacology of these compounds is poorly understood, but they are suspected to be serotonin uptake inhibitors and potentially monoamine releasers. Said to suppress appetite, produce mild euphoria and reduce anxiety.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "250-500mg" + }, + { + "name": "Common", + "value": "500-1000mg" + }, + { + "name": "Strong", + "value": "1000-2000mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "180-360 minutes" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-50mg" + }, + { + "name": "Strong", + "value": "50-150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "60-150 minutes" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "30-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-250mg." + } + ], + "duration": [ + { + "name": "Duration", + "value": "90-150 minutes" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Smoking", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 380, + "name": "Kava", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/kava", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Kava.shtml", + "summary": "Tropical evergreen shrub with large heart-shaped leaves and woody stems. Its thick roots are mashed or ground and made into a cold and bitter-tasting beverage used similarly to alcohol. It has a long history of ritual and recreational use in Pacific Polynesia and is now a common herbal product, used widely by those in certain societies as part of a 'Kava Culture.'", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-70mg" + }, + { + "name": "Common", + "value": "70-150mg" + }, + { + "name": "Strong", + "value": "150-200mg" + }, + { + "name": "Heavy", + "value": "300mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "9-18 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 381, + "name": "Ketamine", + "aliases": [ + "cat tranquilizer", + "k", + "ket", + "ketalar", + "ketanest", + "ketaset", + "kittens", + "kitty", + "special k" + ], + "aliasesStr": "cat tranquilizer,k,ket,ketalar,ketanest,ketaset,kittens,kitty,special k", + "url": "https://psychonautwiki.org/wiki/Ketamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Ketamine.shtml", + "summary": "A short acting dissociative anaesthetic and hallucinogen commonly used in emergency medicine. It is the prototypical dissociative, and is widely used at sub-anesthetic doses recreationally. Small doses are comparable with alcohol, while larger doses are immobilising and lead to psychedelic experiences: the \"K-Hole.\"", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderate to high abuse potential and produces psychological dependence with chronic use", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 300 mg" + }, + { + "name": "Strong", + "value": "300 - 450 mg" + }, + { + "name": "Heavy", + "value": "450 mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "5 - 20 minutes" + }, + { + "name": "Peak", + "value": "45 - 90 minutes" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "4 - 8 hours" + } + ], + "bioavailability": "17%" + }, + { + "name": "Sublingual", + "dosage": null, + "duration": null, + "bioavailability": "20% - 29%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 75 mg" + }, + { + "name": "Strong", + "value": "75 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 1.5 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ], + "bioavailability": "45%" + }, + { + "name": "Intramuscular", + "duration": [ + { + "name": "Onset", + "value": "2-7.5 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Intravenous", + "duration": [ + { + "name": "Onset", + "value": "0-2 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Low Risk & Synergy", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Low Risk & Synergy", + "name": "5-MeO-xxT" + }, + { + "status": "Dangerous", + "note": "Both substances cause ataxia and bring a very high risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.", + "name": "Amphetamines" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position.", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "note": "No unexpected interactions.", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Low Risk & Synergy", + "note": "Ketamine and psychedelics tend to potentiate each other - go slowly.", + "name": "DOx" + }, + { + "status": "Low Risk & No Synergy", + "name": "DXM" + }, + { + "status": "Dangerous", + "note": "Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Caution", + "note": "MAO-B inhibitors appear to increase the potency of Ketamine. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available", + "name": "MAOIs" + }, + { + "status": "Low Risk & Synergy", + "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Low Risk & Synergy", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Dangerous", + "note": "Both substances bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.", + "name": "Opioids" + }, + { + "status": "Low Risk & Synergy", + "name": "PCP" + }, + { + "status": "Low Risk & No Synergy", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "name": "Tramadol" + }, + { + "status": "Low Risk & Synergy", + "name": "aMT" + } + ] + }, + { + "id": 382, + "name": "Ketazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/ketazolam", + "experiencesUrl": null, + "summary": "Benzodiazepine derivative that has most of the common benzodiazepine effects. Has been seen to have similar effectiveness when compared to Diazepam, with milder side-effects. Is marketed in few countries.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-60mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "2-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 383, + "name": "Ketobemidone", + "aliases": [ + "kbd" + ], + "aliasesStr": "kbd", + "url": "https://drugs.tripsit.me/ketobemidone", + "experiencesUrl": null, + "summary": "An opioid analgesic drug that also acts as an NDMA antagonist. Found to be as potent as morphine in physical side effects, and has high potential for addiction like all opioids do. Overdose may lead to respiratory depression/death. Do not mix with CNS depressants or stimulants. Caution should be used for asthmatic users.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-60 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ], + "bioavailability": "34% +/- 10%" + } + ], + "interactions": null + }, + { + "id": 384, + "name": "Khat", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/khat", + "experiencesUrl": null, + "summary": "A shrub whose leaves contain Cathinone and Cathine, they are mostly chewed for the stimulant effect they provide. Very long history of human use.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Chewed", + "duration": [ + { + "name": "Onset", + "value": "10-15 minutes" + }, + { + "name": "Duration", + "value": "30-120 minutes" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 385, + "name": "Kratom", + "aliases": [ + "ketum", + "kratom or kratum", + "mitragyna speciosa", + "กระท่อม (thai)" + ], + "aliasesStr": "ketum,kratom or kratum,mitragyna speciosa,กระท่อม (thai)", + "url": "https://psychonautwiki.org/wiki/Kratom", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Kratom.shtml", + "summary": "A drug made out of the leaves of Mitragyna Speciosa, which is related to coffee. Stimulating at lower doses, with opioid effects at higher doses. Frequent heavy use can cause physical addiction and withdrawals.", + "reagents": null, + "classes": { + "chemical": [ + "Indole_alkaloids" + ], + "psychoactive": [ + "Stimulants", + "Opioids" + ] + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": "produces dependence with chronic use and has a high abuse potential", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 g" + }, + { + "name": "Light", + "value": "2 - 3 g" + }, + { + "name": "Common", + "value": "3 - 5 g" + }, + { + "name": "Strong", + "value": "5 - 8 g" + }, + { + "name": "Heavy", + "value": "8 g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "3 - 6 hours" + } + ] + }, + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "0.5-1.5g" + }, + { + "name": "Common", + "value": "1.5-3g" + }, + { + "name": "Strong", + "value": "3-6g" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-40 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 386, + "name": "Theanine", + "aliases": [ + "l-theanine", + "l-γ-glutamylethylamide and n5-ethyl-l-glutamine" + ], + "aliasesStr": "l-theanine,l-γ-glutamylethylamide and n5-ethyl-l-glutamine", + "url": "https://psychonautwiki.org/wiki/Theanine", + "experiencesUrl": null, + "summary": "An Amino acid that is structural similar to Glutamine. Most report it as a relaxing agent without much sedation. Most commonly found tea. Usually mixed with Caffeine.", + "reagents": null, + "classes": { + "chemical": [ + "Amino_acid_analogue" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "5 days", + "zero": "10 days" + }, + "crossTolerances": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "75 - 175 mg" + }, + { + "name": "Common", + "value": "175 - 300 mg" + }, + { + "name": "Strong", + "value": "300 - 500 mg" + }, + { + "name": "Heavy", + "value": "500 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 387, + "name": "Librium", + "aliases": [ + "chlordiazepoxide" + ], + "aliasesStr": "chlordiazepoxide", + "url": "https://drugs.tripsit.me/librium", + "experiencesUrl": null, + "summary": "Chlordiazepoxide, a medium-acting benzodiazepine drug prescribed mostly for sleep purposes. Sedative and hypnotic, it may cause lowered inhibitions and amnesia in high doses.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Heavy", + "value": "20-40mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "1-14 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 388, + "name": "Vyvanse", + "aliases": [ + "elvanse", + "lisdexamfetamine", + "lisdexamphetamine", + "lisdextroamfetamine", + "lisdextroamphetamine" + ], + "aliasesStr": "elvanse,lisdexamfetamine,lisdexamphetamine,lisdextroamfetamine,lisdextroamphetamine", + "url": "https://psychonautwiki.org/wiki/Lisdexamfetamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Lisdexamfetamine.shtml", + "summary": "Also known as lisdexamphetamine, this drug is a CNS stimulant often prescribed for ADHD, narcolepsy and obesity. It is also a pro-drug for dextroamphetamine, and functions as a method for providing extended-release stimulation. It is sometimes prescribed alongside an SSRI for depression.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 14 hours" + }, + { + "name": "Onset", + "value": "60 - 90 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 389, + "name": "Loprazolam", + "aliases": [ + "dormonoct" + ], + "aliasesStr": "dormonoct", + "url": "https://drugs.tripsit.me/loprazolam", + "experiencesUrl": null, + "summary": "Is an Imidazolobenzidazepine derivative that has all the classic benzodiazepine effects. Is usually only prescribed for a short amount of time for insomnia.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.25-0.5mg" + }, + { + "name": "Common", + "value": "0.5-1.5mg" + }, + { + "name": "Strong", + "value": "1.5-3mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-50 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 390, + "name": "Lorazepam", + "aliases": [ + "ativan", + "lorsilan", + "orfidal" + ], + "aliasesStr": "ativan,lorsilan,orfidal", + "url": "https://psychonautwiki.org/wiki/Lorazepam", + "experiencesUrl": null, + "summary": "An intermediate acting benzodiazepine commonly known as Ativan, commonly prescribed as an alternative to Xanax. Sedating, hypnotic and anxiolytic. Potential to induce amnesia and lowered inhibitions in overdose. Do not combine with other depressants.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Strong", + "value": "1.5 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 - 3 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + } + ], + "bioavailability": "85-90%" + }, + { + "name": "Intramuscular", + "dosage": [ + { + "name": "Light", + "value": "0.25-0.5mg" + }, + { + "name": "Common", + "value": "0.5-1mg" + }, + { + "name": "Strong", + "value": "1-2mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 391, + "name": "Lormetazepam", + "aliases": [ + "noctamid" + ], + "aliasesStr": "noctamid", + "url": "https://drugs.tripsit.me/lormetazepam", + "experiencesUrl": null, + "summary": "Relatively rare prescription benzodiazepine. Short acting with a short half life. Generally only seen in the Netherlands. Sedative, hypnotic and anxiolytic.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ], + "bioavailability": "80%" + } + ], + "interactions": null + }, + { + "id": 392, + "name": "LSA", + "aliases": [ + "ergine", + "hbmg", + "hbw", + "hbwr", + "morning", + "morning_glory", + "morningglory", + "ololiuqui" + ], + "aliasesStr": "ergine,hbmg,hbw,hbwr,morning,morning_glory,morningglory,ololiuqui", + "url": "https://psychonautwiki.org/wiki/LSA", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_LSA.shtml", + "summary": "A chemical found in Morning Glory and Hawaiian Baby Woodrose seeds, which are often legally available. Has mental effects similar to LSD, although with almost no visual effects. It is famous for being very nauseating, and for causing excessive time dilation at higher doses.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "tolerance": { + "full": "almost immediately after ingestion", + "half": null, + "zero": "7 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "HBWR", + "dosage": [ + { + "name": "Light", + "value": "1-2seeds" + }, + { + "name": "Common", + "value": "2-6seeds" + }, + { + "name": "Strong", + "value": "6-14seeds" + }, + { + "name": "Heavy", + "value": "14seeds+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-180 minutes" + }, + { + "name": "Duration", + "value": "4-10 hours" + }, + { + "name": "After effects", + "value": "Some" + } + ] + }, + { + "name": "Morning_Glory", + "dosage": [ + { + "name": "Light", + "value": "50-100seeds" + }, + { + "name": "Common", + "value": "100-250seeds" + }, + { + "name": "Strong", + "value": "250-400seeds" + }, + { + "name": "Heavy", + "value": "400seeds+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-180 minutes" + }, + { + "name": "Duration", + "value": "4-10 hours" + }, + { + "name": "After effects", + "value": "Some" + } + ] + } + ], + "interactions": null + }, + { + "id": 393, + "name": "LSD", + "aliases": [ + "acid", + "blotter", + "cid", + "l", + "lsd-25", + "lucy", + "tabs" + ], + "aliasesStr": "acid,blotter,cid,l,lsd-25,lucy,tabs", + "url": "https://psychonautwiki.org/wiki/LSD", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_LSD.shtml", + "summary": "LSD is a popular psychedelic with a relatively long history of use and research, and as such is known to be relatively safe despite its extremely high potency. It is the archetypical psychedelic to which all others are compared, and remains in popular usage.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "extremely low toxicity relative to dose" + ], + "addictionPotential": "non-addictive with a low abuse potential", + "tolerance": { + "full": "almost immediately after ingestion", + "half": null, + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelics" + ], + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "15 µg" + }, + { + "name": "Light", + "value": "25 - 75 µg" + }, + { + "name": "Common", + "value": "75 - 150 µg" + }, + { + "name": "Strong", + "value": "150 - 300 µg" + }, + { + "name": "Heavy", + "value": "300 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "12 - 48 hours" + } + ], + "bioavailability": "71% - 71%" + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-100ug" + }, + { + "name": "Common", + "value": "100-150ug" + }, + { + "name": "Strong", + "value": "175-225ug" + }, + { + "name": "Heavy", + "value": "250ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "9-14 hours" + }, + { + "name": "After effects", + "value": "12-24 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Low Risk & Synergy", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Low Risk & Synergy", + "name": "5-MeO-xxT" + }, + { + "status": "Low Risk & Decrease", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Caffeine" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Low Risk & Synergy", + "name": "DOx" + }, + { + "status": "Low Risk & Synergy", + "name": "DXM" + }, + { + "status": "Low Risk & Decrease", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Decrease", + "name": "MAOIs" + }, + { + "status": "Low Risk & Synergy", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Low Risk & Synergy", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & No Synergy", + "name": "Opioids" + }, + { + "status": "Low Risk & Synergy", + "name": "PCP" + }, + { + "status": "Low Risk & Decrease", + "name": "SSRIs" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.", + "name": "Tramadol" + }, + { + "status": "Low Risk & Synergy", + "name": "aMT" + } + ] + }, + { + "id": 394, + "name": "LSM-775", + "aliases": [ + "lsm" + ], + "aliasesStr": "lsm", + "url": "https://psychonautwiki.org/wiki/LSM-775", + "experiencesUrl": null, + "summary": "Psychedelic of the lysergamide class, less potent by weight and produces a rather mild, dreamy and even sedating trip compared to its bigger brother LSD.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelics" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "250 µg" + }, + { + "name": "Light", + "value": "500 - 750 µg" + }, + { + "name": "Common", + "value": "750 - 1250 µg" + }, + { + "name": "Strong", + "value": "1250 - 1500 µg" + }, + { + "name": "Heavy", + "value": "1500 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 395, + "name": "LSZ", + "aliases": [ + "diazedine", + "la-ss-az", + "lambda" + ], + "aliasesStr": "diazedine,la-ss-az,lambda", + "url": "https://psychonautwiki.org/wiki/LSZ", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_LSZ.shtml", + "summary": "A lysergamide very similar to LSD usually distinguishable only by its shorter duration, though some subjective reports have noted it may be slightly more introspective and slightly less confusing.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "100 - 150 µg" + }, + { + "name": "Common", + "value": "150 - 300 µg" + }, + { + "name": "Strong", + "value": "300 - 400 µg" + }, + { + "name": "Heavy", + "value": "400 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 396, + "name": "Mandragora", + "aliases": [ + "mandrake" + ], + "aliasesStr": "mandrake", + "url": "https://psychonautwiki.org/wiki/Mandragora", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 397, + "name": "Mandragora officinarum (botany)", + "aliases": [ + "mandrake" + ], + "aliasesStr": "mandrake", + "url": "https://psychonautwiki.org/wiki/Mandragora_officinarum_(botany)", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 398, + "name": "Marinol", + "aliases": [ + "cesamet", + "delta9-tetrahydrocannabinol", + "delta9-thc", + "dronabinol", + "syndros", + "δ9--tetrahydrocannabinol", + "δ9-thc" + ], + "aliasesStr": "cesamet,delta9-tetrahydrocannabinol,delta9-thc,dronabinol,syndros,δ9--tetrahydrocannabinol,δ9-thc", + "url": "https://drugs.tripsit.me/marinol", + "experiencesUrl": null, + "summary": "Synthetically created Δ9-THC, the main psychoactive ingredient in cannabis.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-30mg" + }, + { + "name": "Strong", + "value": "30-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Oral hours" + }, + { + "name": "Duration", + "value": "4-12 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 399, + "name": "MBDB", + "aliases": [ + "eden", + "methyl-j" + ], + "aliasesStr": "eden,methyl-j", + "url": "https://drugs.tripsit.me/mbdb", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MBDB.shtml", + "summary": "A rare entactogenic drug and analogue of MDMA possibly first synthesised by David Nichols. Potentially less potent than related drugs of its type. Sometimes referred to as a 'watered down MDMA.'", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "150-180mg" + }, + { + "name": "Common", + "value": "180-210mg" + }, + { + "name": "Strong", + "value": "210-250mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "3-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 400, + "name": "MBZP", + "aliases": [ + "methylbenylpiperazine" + ], + "aliasesStr": "methylbenylpiperazine", + "url": "https://drugs.tripsit.me/mbzp", + "experiencesUrl": null, + "summary": "A stimulant drug which is a derivative of BZP.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-80mg" + }, + { + "name": "Common", + "value": "80-120mg" + }, + { + "name": "Strong", + "value": "120-160mg" + }, + { + "name": "Heavy", + "value": "160-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 401, + "name": "MCPP", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/MCPP", + "experiencesUrl": null, + "summary": "A phenylpiperazine stimulant first developed in the 1970s before being sold in the RC market, often mislabelled as MDMA. Said to have very unpleasant effects such as anxiogenesis and headaches.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_piperazines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "20 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 120 mg" + }, + { + "name": "Strong", + "value": "120 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "3 - 8 hours" + } + ] + }, + { + "name": "60", + "duration": [ + { + "name": "Onset", + "value": "minutes. minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 402, + "name": "MDA", + "aliases": [ + "sally", + "sass", + "tenamfetamine" + ], + "aliasesStr": "sally,sass,tenamfetamine", + "url": "https://psychonautwiki.org/wiki/MDA", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MDA.shtml", + "summary": "A stimulant and empathogen. Similar to MDMA but typically produces more visuals than MDMA. Known to be more neurotoxic than MDMA, and is a minor metabolite of MDMA. Duration and onset similar to MDMA. The common Marquis reagent test cannot differentiate MDA and MDMA.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics", + "Entactogens" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "repeated and heavy usage", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "40 - 60 mg" + }, + { + "name": "Common", + "value": "60 - 100 mg" + }, + { + "name": "Strong", + "value": "100 - 145 mg" + }, + { + "name": "Heavy", + "value": "145 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "2.5 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 403, + "name": "MDAI", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/MDAI", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MDAI.shtml", + "summary": "A selective serotonin releasing agent which is rarely used without a stimulant to obtain desirable effects. Previously believed not to be neuruotoxic, however MDAI has been implicated in several lethal and non-lethal intoxications, and as such may pose more of a risk to health than previously believed.", + "reagents": null, + "classes": { + "chemical": [ + "Aminoindane" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "somewhat habit-forming with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "entactogens" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "40 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 175 mg" + }, + { + "name": "Strong", + "value": "175 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 404, + "name": "MDEA", + "aliases": [ + "eve", + "mde" + ], + "aliasesStr": "eve,mde", + "url": "https://psychonautwiki.org/wiki/MDEA", + "experiencesUrl": null, + "summary": "A quite rare empathogen closely related to MDMA. Yet is less potent than the prior.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "MDxx", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "1-1.5 months", + "zero": "2-3 months" + }, + "crossTolerances": [ + "dopamine", + "serotonin|serotonergic", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "70 - 120 mg" + }, + { + "name": "Common", + "value": "120 - 180 mg" + }, + { + "name": "Strong", + "value": "180 - 225 mg" + }, + { + "name": "Heavy", + "value": "225 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "12 - 48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 405, + "name": "MDMA", + "aliases": [ + "adam", + "beans", + "e", + "ecstasy", + "emma", + "mandy", + "md", + "molly", + "rolls", + "x", + "xtc" + ], + "aliasesStr": "adam,beans,e,ecstasy,emma,mandy,md,molly,rolls,x,xtc", + "url": "https://psychonautwiki.org/wiki/MDMA", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MDMA.shtml", + "summary": "The world's most popular empathogen with powerful pro-social effects. Has been strongly linked to cognitive decline in excess. Popular at parties, it is often sold in powder or in pills, and may be adulterated with other similar chemicals.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "MDxx", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "1 month", + "zero": "2.5 months" + }, + "crossTolerances": [ + "dopaminergic", + "serotonergic", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "15 - 55 mg" + }, + { + "name": "Common", + "value": "55 - 125 mg" + }, + { + "name": "Strong", + "value": "125 - 180 mg" + }, + { + "name": "Heavy", + "value": "180 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "12 - 48 hours" + } + ] + }, + { + "name": "Insufflated/Rectal", + "dosage": [ + { + "name": "Light", + "value": "30-70mg" + }, + { + "name": "Common", + "value": "70-120mg" + }, + { + "name": "Strong", + "value": "120-165mg" + }, + { + "name": "Heavy", + "value": "165mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-70 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-72 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Caution", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Caution", + "note": "Some of the 5-MeO tryptamines are a bit unpredictable and should be mixed with MDMA with care", + "name": "5-MeO-xxT" + }, + { + "status": "Caution", + "note": "Both MDMA and alcohol cause dehydration. Approach this combination with caution, moderation and sufficient hydration. More than a small amount of alcohol will dull the euphoria of MDMA", + "name": "Alcohol" + }, + { + "status": "Low Risk & Synergy", + "note": "Amphetamines increase the neurotoxic effects of MDMA", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Caution", + "note": "Caffiene is not really necessary with MDMA and increases any neurotoxic effects from MDMA", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "note": "Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible.", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "Cocaine blocks some of the desirable effects of MDMA while increasing the risk of heart attack.", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Caution", + "note": "The combined stimulating effects of the two can be uncomfortable. Coming down on the MDMA while the DOx is still active can be quite anxiogenic. ", + "name": "DOx" + }, + { + "status": "Dangerous", + "name": "DXM" + }, + { + "status": "Caution", + "note": "Large amounts of GHB/GBL may overwhelm the effects of MDMA on the comedown.", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "note": "No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Dangerous", + "note": "MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably. MAO-A inhibitors with MDMA will lead to hypertensive crises.", + "name": "MAOIs" + }, + { + "status": "Caution", + "note": "There have been reports of risky serotonergic interactions when the two are taken at the same time, but MXE taken to the end of an MDMA experience does not appear to cause the same issues.", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Caution", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & No Synergy", + "name": "Opioids" + }, + { + "status": "Unsafe", + "note": "This combination can easily lead to hypermanic states", + "name": "PCP" + }, + { + "status": "Low Risk & Decrease", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "note": "Tramadol and stimulants both increase the risk of seizures.", + "name": "Tramadol" + }, + { + "status": "Dangerous", + "name": "aMT" + } + ] + }, + { + "id": 406, + "name": "MDOH", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/mdoh", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MDOH.shtml", + "summary": "An entactogen, stimulant and psychedelic first synthesised by Alexander Shulgin, MDOH is an analogue of MDA. Described as highly psychedelic, it is likely a serotonin releasing agent. It has not seen widespread use, perhaps due to a number of reported negative side effects such as urinary retention and a heavy comedown.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "80mg" + }, + { + "name": "Light", + "value": "100-120mg" + }, + { + "name": "Common", + "value": "120-150mg" + }, + { + "name": "Heavy", + "value": "150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 407, + "name": "MDPA", + "aliases": [ + "methylenedioxyphenylacetamide" + ], + "aliasesStr": "methylenedioxyphenylacetamide", + "url": "https://drugs.tripsit.me/mdpa", + "experiencesUrl": null, + "summary": "An obscure substituted methylenedioxyphenethylamine with practically no history of human use. Its pharmacological profile is largely unknown, but potentially exhibits similar properties to other MDxx compounds. May be a monoamine releaser, reuptake inhibitor or both.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "75-125mg" + }, + { + "name": "Common", + "value": "125-175mg" + }, + { + "name": "Strong", + "value": "175-250mg" + }, + { + "name": "Heavy", + "value": "250+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 408, + "name": "Mdphp", + "aliases": [ + "monkey-dust" + ], + "aliasesStr": "monkey-dust", + "url": "https://drugs.tripsit.me/mdphp", + "experiencesUrl": null, + "summary": "MDPHP aka 'Monkey-Dust' is a substituted cathinone and pyrovalerone which has been sold as an alternative to a-PHP and MDPV. Said to be less intense than MDPV with similar effects. MDPHP potency is said to vary widely, and there are reports of mixed composition batches containing other drugs. Very little is known about MDPHP in terms of toxicity, pharmacology and metabolism.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "20-35mg" + }, + { + "name": "Strong", + "value": "35+mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "2-16h" + } + ] + }, + { + "name": "Insufflated/Inhaled", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20+mg" + } + ], + "duration": [ + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "2-36h" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 409, + "name": "MDPV", + "aliases": [ + "bath salts", + "bath_salts", + "nrg-1" + ], + "aliasesStr": "bath salts,bath_salts,nrg-1", + "url": "https://psychonautwiki.org/wiki/MDPV", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MDPV.shtml", + "summary": "MDPV is a potent, and extremely compulsive synthetic euphoric stimulant, which shares some empathogenic effects with MDMA. Has a reputation for causing psychosis. MDPV has been found in products sold as \"bath salts\", \"plant food/fertilizer\", and in some \"ecstasy.\"", + "reagents": null, + "classes": { + "chemical": [ + "MDxx", + "Pyrrolidinophenone", + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "4 - 8 mg" + }, + { + "name": "Common", + "value": "8 - 14 mg" + }, + { + "name": "Strong", + "value": "14 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 7 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 4 hours" + }, + { + "name": "Offset", + "value": "0.5 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1-3mg" + }, + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-11mg" + }, + { + "name": "Strong", + "value": "10-20mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-20 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "2-48 hours" + } + ] + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Threshold", + "value": "1-5mg" + }, + { + "name": "Light", + "value": "3-8mg" + }, + { + "name": "Common", + "value": "6-12mg" + }, + { + "name": "Strong", + "value": "10-25mg" + } + ], + "duration": [ + { + "name": "After effects", + "value": "2-48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 410, + "name": "Mebroqualone", + "aliases": [ + "mbq" + ], + "aliasesStr": "mbq", + "url": "https://drugs.tripsit.me/mebroqualone", + "experiencesUrl": null, + "summary": "A short acting analogue of Methaqualone, that is much more potent.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "3-5mg" + }, + { + "name": "Light", + "value": "5-8mg" + }, + { + "name": "Common", + "value": "8-15mg" + }, + { + "name": "Strong", + "value": "15-20mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "45-90 minutes" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Vaporized", + "dosage": [ + { + "name": "Threshold", + "value": "2-3mg" + }, + { + "name": "Light", + "value": "3-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "20-40 minutes" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "60-120 minutes" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "30-60 minutes" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 411, + "name": "Meclonazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/meclonazepam", + "experiencesUrl": null, + "summary": "A benzodiazepine related to clonazepam discovered by Hoffman-LaRoche in the 1960s. Potentially useful in treating schistosomiasis. Has been sold on the grey market as a recreational drug but has not seen widespread popularity.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "3-6mg" + }, + { + "name": "Heavy", + "value": "6-12mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "9-15 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 412, + "name": "Medazepam", + "aliases": [ + "azepamid", + "mezapam", + "nobrium", + "raporan", + "rudotel", + "talis" + ], + "aliasesStr": "azepamid,mezapam,nobrium,raporan,rudotel,talis", + "url": "https://drugs.tripsit.me/medazepam", + "experiencesUrl": null, + "summary": "Benzodiazepine derivative that has all of the classic benzodiazepine effects. Is a long-acting benzodiazepine drug (Half life of 36-200 hours) Is rarely prescribed in most countries. Is also a prodrug for Diazepam. Think of it as Desoxy-Diazepam if you'd like to.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-40mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "8-16 hours" + }, + { + "name": "After effects", + "value": "1-172 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 413, + "name": "Melatonin", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Melatonin", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Melatonin.shtml", + "summary": "A naturally occurring hormone produced in the body, which promotes sleep at certain times in the day based on the circadian rhythm. It is also commonly available as a drug to treat insomnia and promote a proper sleep cycle. It can be used to promote sleepfulness at the tail-end of drug experiences, though it is not particularly hypnotic.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Oneirogen" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "after prolonged and repeated usage", + "half": "7 days", + "zero": "14 days" + }, + "crossTolerances": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + } + ], + "bioavailability": "15% - 15%" + } + ], + "interactions": null + }, + { + "id": 414, + "name": "MEM", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/mem", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MEM.shtml", + "summary": "A rare stimulant, psychedelic and amphetamine discovered by Alexander Shulgin. Related to the DOx class of drugs, little is known about this obscure compound's pharmacology, however it is likely to be potent and have a long duration.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15mg" + }, + { + "name": "Common", + "value": "25-35mg" + }, + { + "name": "Strong", + "value": "35-45mg+." + } + ], + "duration": [ + { + "name": "Onset", + "value": "Within minutes" + }, + { + "name": "Duration", + "value": "8-16 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 415, + "name": "Memantine", + "aliases": [ + "both extended-release)", + "ebixa", + "memaxa", + "namenda", + "namenda xr", + "namzaric (with donepezil" + ], + "aliasesStr": "both extended-release),ebixa,memaxa,namenda,namenda xr,namzaric (with donepezil", + "url": "https://psychonautwiki.org/wiki/Memantine", + "experiencesUrl": null, + "summary": "An NMDA-antagonist that if used recreationally can cause to a very prolonged \"hole\" lasting up to 16+ hours.", + "reagents": null, + "classes": { + "chemical": [ + "Adamantanes" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "unknown", + "tolerance": null, + "crossTolerances": [ + "dissociatives" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "30 - 70 mg" + }, + { + "name": "Common", + "value": "70 - 110 mg" + }, + { + "name": "Strong", + "value": "110 - 170 mg" + }, + { + "name": "Heavy", + "value": "170 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "~ 24 - 72 hours" + }, + { + "name": "Onset", + "value": "2 - 3 hours" + }, + { + "name": "Come up", + "value": "2 - 3 hours" + }, + { + "name": "Peak", + "value": "3 - 12 hours" + }, + { + "name": "Offset", + "value": "5 - 24 hours" + }, + { + "name": "After effects", + "value": "24 - 48 hours" + } + ], + "bioavailability": "41 - 63%" + } + ], + "interactions": null + }, + { + "id": 416, + "name": "Mephedrone", + "aliases": [ + "4-methylmethcathinone", + "4-mmc", + "4mmc", + "drone", + "m-cat", + "meow", + "meow meow" + ], + "aliasesStr": "4-methylmethcathinone,4-mmc,4mmc,drone,m-cat,meow,meow meow", + "url": "https://psychonautwiki.org/wiki/Mephedrone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4Methylmethcathinone.shtml", + "summary": "A shortlived euphoric stimulant, developed as an analogue of MDMA, which was extremely popular in the research chemical scene before being banned. Commonly seen on street markets but rarer online. Very strong urge to redose compulsively.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "15 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 45 mg" + }, + { + "name": "Common", + "value": "45 - 80 mg" + }, + { + "name": "Strong", + "value": "80 - 125 mg" + }, + { + "name": "Heavy", + "value": "125 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 417, + "name": "4-MPM", + "aliases": [ + "4-methylphenmetrazine" + ], + "aliasesStr": "4-methylphenmetrazine", + "url": "https://drugs.tripsit.me/mephenmetrazine", + "experiencesUrl": null, + "summary": "4-Methylphenmetrazine is an empathogen of the phenylmorpholine class that seems to have a very rapid tolerance build up.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-25mg" + }, + { + "name": "Strong", + "value": "25-40mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-25mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 418, + "name": "Mephtetramine", + "aliases": [ + "mtta" + ], + "aliasesStr": "mtta", + "url": "https://drugs.tripsit.me/mephtetramine", + "experiencesUrl": null, + "summary": "Has a Phenpropylamine backbone like Methylphenidate. Seems barely active past negative physical effects. Only reports that include activity past the prior were mixing it with another substance.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 419, + "name": "Mescaline", + "aliases": [ + "buttons", + "mesc", + "san", + "san-pedro" + ], + "aliasesStr": "buttons,mesc,san,san-pedro", + "url": "https://psychonautwiki.org/wiki/Mescaline", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Mescaline.shtml", + "summary": "A psychedelic of the phenethylamine family. Found in psychedelic cacti that have long been used by peoples native to the Southwestern US and Mexico, including Peyote and San Pedro cacti, among others. Can be found as cactus pulp, as an extract from cacti, or as a synthetic substance created in a lab.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 400 mg" + }, + { + "name": "Strong", + "value": "400 - 800 mg" + }, + { + "name": "Heavy", + "value": "800 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 14 hours" + }, + { + "name": "Onset", + "value": "45 - 90 minutes" + }, + { + "name": "Come up", + "value": "60 - 120 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 36 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Caution", + "name": "2C-T-x" + }, + { + "status": "Caution", + "name": "2C-x" + }, + { + "status": "Caution", + "note": "The 5-MeO class of tryptamines can be unpredictable in their interactions", + "name": "5-MeO-xxT" + }, + { + "status": "Low Risk & Decrease", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "note": "High doses of caffeine are uncomfortable and this will be magnified by psychedelics", + "name": "Caffeine" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "The focus and anxiety caused by stimulants is magnified by psychedelics and results in an increased risk of thought loops", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Caution", + "name": "DOx" + }, + { + "status": "Low Risk & Synergy", + "name": "DXM" + }, + { + "status": "Low Risk & Decrease", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Caution", + "name": "MAOIs" + }, + { + "status": "Low Risk & Synergy", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Caution", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & No Synergy", + "name": "Opioids" + }, + { + "status": "Low Risk & Synergy", + "name": "PCP" + }, + { + "status": "Low Risk & Decrease", + "name": "SSRIs" + }, + { + "status": "Unsafe", + "note": "This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.", + "name": "Tramadol" + }, + { + "status": "Dangerous", + "name": "aMT" + } + ] + }, + { + "id": 420, + "name": "MET", + "aliases": [ + "methylethyltryptamine" + ], + "aliasesStr": "methylethyltryptamine", + "url": "https://psychonautwiki.org/wiki/MET", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MET.shtml", + "summary": "A rare psychedelic tryptamine, related to DMT and DET. Little information exists about the effects or pharmacology of this drug.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": "60 - 90 mg" + }, + { + "name": "Heavy", + "value": "90 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 75 minutes" + }, + { + "name": "Onset", + "value": "30 - 60 seconds" + }, + { + "name": "Peak", + "value": "10 - 20 minutes" + }, + { + "name": "Offset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "20 - 60 minutes" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "40 mg" + }, + { + "name": "Light", + "value": "60 - 120 mg" + }, + { + "name": "Common", + "value": "120 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "1 - 2 hours" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 35 mg" + }, + { + "name": "Heavy", + "value": "35 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1 - 1.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2.5 hours" + }, + { + "name": "After effects", + "value": "4 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 421, + "name": "Metaclazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/metaclazepam", + "experiencesUrl": null, + "summary": "A benzodiazepine derivative. Which is mostly an anxiolytic substance, without strong hypnotic properties that most benzodiazepines have. Its active metabolite is N-desmethylmetaclazepam, which is the main metabolite. Slightly more effective as an anxiolytic than Bromazepam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "9.5mg-18.75mg" + }, + { + "name": "Common", + "value": "18.75mg" + }, + { + "name": "Strong", + "value": "35-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "duration hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 422, + "name": "Metaxalone", + "aliases": [ + "skelaxin" + ], + "aliasesStr": "skelaxin", + "url": "https://drugs.tripsit.me/metaxalone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Metaxalone.shtml", + "summary": "Muscle relaxant, that is used to relieve pain from general pain, and other musculoskeletal conditions.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "400-800mg." + }, + { + "name": "Common", + "value": "800-1600mg." + }, + { + "name": "Strong", + "value": "1600-2400mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 423, + "name": "Methadone", + "aliases": [ + "dolophine" + ], + "aliasesStr": "dolophine", + "url": "https://psychonautwiki.org/wiki/Methadone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methadone.shtml", + "summary": "A synthetic opioid drug used as an analgesic and is often used in detoxification off of other opioids. As it has a much longer half-life.", + "reagents": null, + "classes": { + "chemical": [ + "Diphenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20 - 90 minutes" + }, + { + "name": "Peak", + "value": "6 - 8 hours" + }, + { + "name": "After effects", + "value": "1 - 24 hours" + } + ], + "bioavailability": "40-99%" + } + ], + "interactions": null + }, + { + "id": 424, + "name": "Methallylescaline", + "aliases": [ + "mal" + ], + "aliasesStr": "mal", + "url": "https://psychonautwiki.org/wiki/Methallylescaline", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methallylescaline.shtml", + "summary": "Mescaline analogue first synthesised by Alexander Shulgin, derived from and less potent than allylescaline. A psychedelic phenethylamine which causes stimulation, euphoria and hallucinatory experiences.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "4 - 8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 425, + "name": "Methamnetamine", + "aliases": [ + "methylnaphetamine", + "mnt", + "n-methyl-pal-287" + ], + "aliasesStr": "methylnaphetamine,mnt,n-methyl-pal-287", + "url": "https://drugs.tripsit.me/methamnetamine", + "experiencesUrl": null, + "summary": "A selective serotonin releaser, which also shows some light psychedelic activity. Almost always taken with a stimulant, to cause euphoric effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "60-80mg" + }, + { + "name": "Common", + "value": "80-120mg" + }, + { + "name": "Strong", + "value": "120-150mg" + }, + { + "name": "Heavy", + "value": "150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 426, + "name": "Methamphetamine", + "aliases": [ + "crank", + "desoxyn", + "glass", + "ice", + "meth", + "shard", + "speed", + "tik", + "tina" + ], + "aliasesStr": "crank,desoxyn,glass,ice,meth,shard,speed,tik,tina", + "url": "https://psychonautwiki.org/wiki/Methamphetamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methamphetamine.shtml", + "summary": "A fairly common and very strong CNS stimulant. It is sometimes prescribed in the form of desoxyn for ADHD and severe obesity. In low doses, methamphetamine can elevate mood, increase alertness, concentration, energy and reduces appetite. At higher doses, it can induce mania, psychosis and muscle degeneration among other issues. Tolerant users may report much higher doses than new users.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "rapidly develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulants" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours", + "note": "Up to 12h for irregular users." + }, + { + "name": "Onset", + "value": "7 - 10 seconds" + }, + { + "name": "Come up", + "value": "5 - 10 seconds" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 24 hours" + } + ], + "bioavailability": ">90%" + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 - 150 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "7 - 12 hours", + "note": "Up to 24h for irregular users." + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "2.6 - 3.6 hours" + }, + { + "name": "Peak", + "value": "3 - 5 hours" + }, + { + "name": "Offset", + "value": "3 - 4 hours" + }, + { + "name": "After effects", + "value": "12 - 24 hours" + } + ], + "bioavailability": "~70%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7", + "note": "Up to 12h for irregular users." + }, + { + "name": "Onset", + "value": "3 - 5" + }, + { + "name": "Come up", + "value": "3 - 5" + }, + { + "name": "Peak", + "value": "1.5 - 3 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ], + "bioavailability": ">90%" + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg+" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours", + "note": "Up to 18h for irregular users." + }, + { + "name": "Onset", + "value": "5 - 15 minutes" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "-" + }, + { + "name": "After effects", + "value": "-" + } + ], + "bioavailability": "~99%" + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 - 80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours", + "note": "Up to 18h for irregular users." + }, + { + "name": "Onset", + "value": "15 - 30 seconds" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "-" + }, + { + "name": "After effects", + "value": "-" + } + ], + "bioavailability": "~100%" + } + ], + "interactions": null + }, + { + "id": 427, + "name": "Methaqualone", + "aliases": [ + "ludes", + "mandrax", + "quaaludes", + "qualudes", + "sopor" + ], + "aliasesStr": "ludes,mandrax,quaaludes,qualudes,sopor", + "url": "https://psychonautwiki.org/wiki/Methaqualone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methaqualone.shtml", + "summary": "A pharmaceutical depressant and sedative phased out due to the better safety profile of benzodiazepines, part of the Qualone group of substances. Now very rare, except in South Africa.", + "reagents": null, + "classes": { + "chemical": [ + "Quinazolinone" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "doses of over 300mg can be dangerous for first time users", + "safe at appropriate dosages" + ], + "addictionPotential": "extremely addictive", + "tolerance": { + "full": "within a couple of days of repeated administration", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "GABA|gabaergic", + "depressants" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 - 150 mg" + }, + { + "name": "Light", + "value": "150 - 300 mg" + }, + { + "name": "Common", + "value": "300 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 600 mg" + }, + { + "name": "Heavy", + "value": "600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 minutes" + }, + { + "name": "Come up", + "value": "30 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "6 - 8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 428, + "name": "Methedrone", + "aliases": [ + "bk-pmma" + ], + "aliasesStr": "bk-pmma", + "url": "https://drugs.tripsit.me/methedrone", + "experiencesUrl": null, + "summary": "BK-PMMA Closely related to PMMA and others. Stimulant.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 429, + "name": "MPA", + "aliases": [ + "methiopropamine" + ], + "aliasesStr": "methiopropamine", + "url": "https://psychonautwiki.org/wiki/Methiopropamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methiopropamine.shtml", + "summary": "An analogue of methamphetamine with effects close to amphetamine. Some users report negative side effects including stomach discomfort and sweating. Acts as a selective NDRI.", + "reagents": null, + "classes": { + "chemical": [ + "Thiophene" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "20 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 4 hours" + }, + { + "name": "Offset", + "value": "2 - 3 hours" + }, + { + "name": "After effects", + "value": "1 - 2 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "5 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 60 minutes" + }, + { + "name": "Offset", + "value": "30 - 120 minutes" + }, + { + "name": "After effects", + "value": "6 - 8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 430, + "name": "MXE", + "aliases": [ + "3-meo-2'oxo-pce", + "methoxetamine", + "mexxy" + ], + "aliasesStr": "3-meo-2'oxo-pce,methoxetamine,mexxy", + "url": "https://psychonautwiki.org/wiki/Methoxetamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methoxetamine_.shtml", + "summary": "A popular dissociative drug which is an analogue of ketamine, though less sedating and more potent by weight, with a subjectively more 'complicated' set of effects.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 45 mg" + }, + { + "name": "Strong", + "value": "45 - 70 mg" + }, + { + "name": "Heavy", + "value": "70 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "6 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "Come up", + "value": "30 - 75 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 1.5 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60-75mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "2-48 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Caution", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Low Risk & Synergy", + "note": "Little information exists about this combination.", + "name": "5-MeO-xxT" + }, + { + "status": "Dangerous", + "note": "There is a high risk of memory loss, vomiting and severe ataxia from this combination.", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "Risk of tachycardia, hypertension, and manic states", + "name": "Amphetamines" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess.", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "note": "No likely interactions", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "Stimulants taken with MXE can lead to hypermanic states much more easily, especially if sleep is avoided.", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Caution", + "note": "As an NMDA antagonist MXE potentiates DOx which can be unpleasantly intense", + "name": "DOx" + }, + { + "status": "Low Risk & No Synergy", + "name": "DXM" + }, + { + "status": "Dangerous", + "note": "Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the patient falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Unsafe", + "note": "MAO-B inhibitors appear to increase the potency of MXE. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available", + "name": "MAOIs" + }, + { + "status": "Caution", + "note": "There have been reports of risky serotonergic interactions when the two are taken at the same time, but MXE taken to the end of an MDMA experience does not appear to cause the same issues.", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Caution", + "note": "As an NMDA antagonist MXE potentiates NBOMes which can be unpleasantly intense", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Dangerous", + "note": "This combination can potentiate the effects of the opioid", + "name": "Opioids" + }, + { + "status": "Caution", + "note": "There are no reports available about this combination", + "name": "PCP" + }, + { + "status": "Caution", + "note": "Depending on the SSRI this combination can be unpredictable", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "name": "Tramadol" + }, + { + "status": "Dangerous", + "name": "aMT" + } + ] + }, + { + "id": 431, + "name": "Methoxphenidine", + "aliases": [ + "2-meo-diphenidine", + "2-mxp", + "methoxyphenidine", + "mxp" + ], + "aliasesStr": "2-meo-diphenidine,2-mxp,methoxyphenidine,mxp", + "url": "https://psychonautwiki.org/wiki/Methoxphenidine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methoxphenidine.shtml", + "summary": "A dissociative from the diarylethylamine class, a more potent analogue of diphenidine. Known to be unpredictable, and can cause blackouts.", + "reagents": null, + "classes": { + "chemical": [ + "Diarylethylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30 mg" + }, + { + "name": "Light", + "value": "50 - 75 mg" + }, + { + "name": "Common", + "value": "75 - 120 mg" + }, + { + "name": "Strong", + "value": "120 - 150 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 432, + "name": "METHOXYACETYL-FENTANYL", + "aliases": [ + "desfluoroocfentanil", + "maf" + ], + "aliasesStr": "desfluoroocfentanil,maf", + "url": "https://drugs.tripsit.me/methoxyacetyl-fentanyl", + "experiencesUrl": null, + "summary": "A quite potent fentanyl analogue.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.25-0.5mg" + }, + { + "name": "Common", + "value": "0.5-1.5mg" + }, + { + "name": "Strong", + "value": "1.5mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "10-20 minutes" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 433, + "name": "Methoxyketamine", + "aliases": [ + "2-meo-ketamine" + ], + "aliasesStr": "2-meo-ketamine", + "url": "https://drugs.tripsit.me/methoxyketamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methoxyketamine.shtml", + "summary": "An arylcyclohexylamine drug and analogue of ketamine, though slightly less potent. Produces similar dissociative and anaesthetic effects. Very rare.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5-15mg" + }, + { + "name": "Light", + "value": "15-60mg" + }, + { + "name": "Common", + "value": "60-130mg" + }, + { + "name": "Strong", + "value": "130-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 434, + "name": "Methoxypiperamide", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/methoxypiperamide", + "experiencesUrl": null, + "summary": "Drug of the Piperazine class. The 4-Methoxy-α-keto analogue of Methylbenzylpiperazine. Seemingly inactive on its own. Was sold in tandem with Mephtetramine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 435, + "name": "Methylmethaqualone", + "aliases": [ + "mmq" + ], + "aliasesStr": "mmq", + "url": "https://drugs.tripsit.me/methylmethaqualone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methylmethaqualone.shtml", + "summary": "A more potent analogue of methaqualone with a short duration. Thought to be potentially neurotoxic. Has pro-convulsive effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Vapourized/Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "2-3mg" + }, + { + "name": "Light", + "value": "3-5mg" + }, + { + "name": "Common", + "value": "5-10mg." + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Sublingual", + "duration": [ + { + "name": "Onset", + "value": "10 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Vapourized", + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 436, + "name": "Methylmorphenate", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/methylmorphenate", + "experiencesUrl": null, + "summary": "Stimulant of the phenylmorpholine class, an analogue of Methylphenidate where the piperidine ring has been replaced by a morpholine one, with ~1/10 potency.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 437, + "name": "Methylone", + "aliases": [ + "bk-mdma", + "m1", + "mdmc" + ], + "aliasesStr": "bk-mdma,m1,mdmc", + "url": "https://psychonautwiki.org/wiki/Methylone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Methylone.shtml", + "summary": "βk-MDMA is a cathinone stimulant and empathogen, similar in structure to MDMA, though more stimulating and less empathogenic in comparison. Was very commonly mis-sold as MDMA on the street until it was banned in 2013. The Marquis reagent can differentiate βk-MDMA from MDMA. Less potent than MDMA with a slightly shorter duration.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants", + "Entactogens" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "1 - 3 weeks", + "zero": "3 - 6 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "75 mg" + }, + { + "name": "Light", + "value": "75 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 225 mg" + }, + { + "name": "Strong", + "value": "225 - 325 mg" + }, + { + "name": "Heavy", + "value": "325 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2.5 - 4 hours" + }, + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Come up", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "60 - 90 minutes" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 438, + "name": "Methylphenidate", + "aliases": [ + "biphentin", + "concerta", + "equasym xl", + "methylin", + "mph", + "ritalin" + ], + "aliasesStr": "biphentin,concerta,equasym xl,methylin,mph,ritalin", + "url": "https://psychonautwiki.org/wiki/Methylphenidate", + "experiencesUrl": null, + "summary": "A psychostimulant commonly used in the treatment of ADHD, narcolepsy and obesity, particularly in the EU instead of Adderall. Methylphenidate is also a 5HT1A receptor agonist. Sometimes prescribed off-label to help the withdrawals from cocaine and other stimulants.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenidates" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 2.5 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ], + "bioavailability": "11-52%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 20 minutes" + }, + { + "name": "Come up", + "value": "15 - 40 minutes" + }, + { + "name": "Peak", + "value": "30 - 45 minutes" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 4 hours" + } + ] + }, + { + "name": "Oral-IR", + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Oral-XR", + "duration": [ + { + "name": "Onset", + "value": "30-120 minutes" + }, + { + "name": "Duration", + "value": "8-12 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Insufflated-XR", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Insufflated-IR", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 439, + "name": "Methyprylon", + "aliases": [ + "noludar" + ], + "aliasesStr": "noludar", + "url": "https://drugs.tripsit.me/methyprylon", + "experiencesUrl": null, + "summary": "Sedative of the pipeidinedone family. Was used for treating insomnia, yet is rarely used today due to substances with fewer side effects, such as benzodiazepines.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "150-200mg" + }, + { + "name": "Common", + "value": "200-300mg" + }, + { + "name": "Strong", + "value": "300mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 440, + "name": "Metizolam", + "aliases": [ + "desmethyletizolam", + "metiz" + ], + "aliasesStr": "desmethyletizolam,metiz", + "url": "https://psychonautwiki.org/wiki/Metizolam", + "experiencesUrl": null, + "summary": "Also known as desmethyletizolam, a thienodiazepine similar in effects and structure to etizolam, but around half as potent and with around a 60% longer half-life. A sedative, and hypnotic, it may cause amnesia and lowered inhibitions in excess.", + "reagents": null, + "classes": { + "chemical": [ + "Thienodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "large therapeutic index and margin of safety" + ], + "addictionPotential": "extremely addictive", + "tolerance": { + "full": "within a couple of days of repeated administration", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "thienzodiazepines", + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 1 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 4 mg" + }, + { + "name": "Strong", + "value": "4 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "10 - 30 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 441, + "name": "Mexamine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/mexamine", + "experiencesUrl": null, + "summary": "5-Methoxytryptamine, a tryptamine derivative that naturally occurs in the body at low levels. No evidence of recreational use. Apparently enhances dreams.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 442, + "name": "Mexazolam", + "aliases": [ + "melex", + "sedoxil" + ], + "aliasesStr": "melex,sedoxil", + "url": "https://drugs.tripsit.me/mexazolam", + "experiencesUrl": null, + "summary": "Benzodiazepine derivative that has been trialed for anxiety and was found to be effective for anxiety at one week week follow-ups yet after three weeks it had lost its therapeutic anxiolytic properties and becoming no more effective than placebo.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.25-0.5mg" + }, + { + "name": "Common", + "value": "0.5-1.5mg" + }, + { + "name": "Strong", + "value": "1.5-2mg" + }, + { + "name": "Heavy", + "value": "2-3mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-45 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 443, + "name": "Mexedrone", + "aliases": [ + "4-mmc-meo", + "4-mmeoc" + ], + "aliasesStr": "4-mmc-meo,4-mmeoc", + "url": "https://psychonautwiki.org/wiki/Mexedrone", + "experiencesUrl": null, + "summary": "Mexedrone is a stimulant drug of the cathinone class. It alters the reuptake of serotonin, dopamine, and norepinephrine to cause euphoria, and is similar in effects to mephedrone. It is considered a designer drug and is in a legally grey area globally.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 mg" + }, + { + "name": "Light", + "value": "100 - 150 mg" + }, + { + "name": "Common", + "value": "150 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 350 mg" + }, + { + "name": "Heavy", + "value": "350 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "50-80mg" + }, + { + "name": "Common", + "value": "80-120mg" + }, + { + "name": "Strong", + "value": "120-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "3-10 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 444, + "name": "Midazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/midazolam", + "experiencesUrl": null, + "summary": "A common hypnotic, sedative and anxiolytic benzodiazepine. High doses may cause amnesia and loss of inhibitions. Unusually, it is water soluble, and commonly used as a premedication for sedation as the solubility makes it better for IV use than other benzodiazepines.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15-30mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-40 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Common", + "value": "7-15mg" + }, + { + "name": "Strong", + "value": "15-25mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ], + "bioavailability": "55%" + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Common", + "value": "7-15mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-25 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Intramuscular", + "dosage": [ + { + "name": "Common", + "value": "5-12mg" + }, + { + "name": "Strong", + "value": "12-25mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ], + "bioavailability": "90%" + } + ], + "interactions": null + }, + { + "id": 445, + "name": "MiPLA", + "aliases": [ + "lamide" + ], + "aliasesStr": "lamide", + "url": "https://psychonautwiki.org/wiki/MiPLA", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "low potential for abuse and dependence", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "100 - 150 µg" + }, + { + "name": "Common", + "value": "150 - 200 µg" + }, + { + "name": "Strong", + "value": "200 - 250 µg" + }, + { + "name": "Heavy", + "value": "300 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Come up", + "value": "45 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 446, + "name": "MiPT", + "aliases": [ + "n-methyl-n-isopropyltryptamine" + ], + "aliasesStr": "n-methyl-n-isopropyltryptamine", + "url": "https://psychonautwiki.org/wiki/MiPT", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MIPT.shtml", + "summary": "N-Methyl-N-isopropyltryptamine, a tryptamine analogue of DMT, a very uncommon drug with very few reports of human use. Described as 'more psychedelic than hallucinogenic' users report only mild visuals with some stimulation and cognitive effects. One of the more stable tryptamines.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 75 mg" + }, + { + "name": "Heavy", + "value": "- mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 8 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "0-2 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "3-5mg" + }, + { + "name": "Common", + "value": "5-15mg" + }, + { + "name": "Strong", + "value": "15-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 447, + "name": "Mirtazapine", + "aliases": [ + "avanza", + "axit", + "mirtaz", + "mirtazon", + "remeron", + "zispin" + ], + "aliasesStr": "avanza,axit,mirtaz,mirtazon,remeron,zispin", + "url": "https://psychonautwiki.org/wiki/Mirtazapine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Piperazinoazepine" + ], + "psychoactive": [ + "Deliriant", + "Antidepressant", + "Depressant" + ] + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3.5 mg" + }, + { + "name": "Light", + "value": "70 - 130 mg" + }, + { + "name": "Common", + "value": "130 - 190 mg" + }, + { + "name": "Strong", + "value": "190 - 250 mg" + }, + { + "name": "Heavy", + "value": "250 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "14 - 24 hours" + }, + { + "name": "Onset", + "value": "15 - 30 min" + }, + { + "name": "Peak", + "value": "90 - 180 min" + }, + { + "name": "Offset", + "value": "2 - 6 hours" + }, + { + "name": "After effects", + "value": "up to 24 hours" + } + ], + "bioavailability": "50%" + } + ], + "interactions": null + }, + { + "id": 448, + "name": "MK-801", + "aliases": [ + "dizocilpine", + "mk801" + ], + "aliasesStr": "dizocilpine,mk801", + "url": "https://drugs.tripsit.me/mk-801", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Dizocilpine.shtml", + "summary": "Dissociative research chemical similar to PCP, and Ketamine. Dizocilpine, also known as MK-801, is a non-competitive antagonist of the NMDA receptor.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "50-100ug" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30mins" + }, + { + "name": "Duration", + "value": "20-36 hours" + }, + { + "name": "After effects", + "value": "1-72 hours" + } + ] + }, + { + "name": "IM", + "duration": [ + { + "name": "Onset", + "value": "45mins" + }, + { + "name": "Duration", + "value": "20-36 hours" + }, + { + "name": "After effects", + "value": "1-72 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 449, + "name": "Moclobemide", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/moclobemide", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Moclobemide.shtml", + "summary": "A reversible MAOI which is prescribed to treat depression and anxiety. Its reversibility and short-acting length of effects often means it is used in \"pharmahuasca\" preparations.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "150mg" + }, + { + "name": "Common", + "value": "300mg" + }, + { + "name": "Strong", + "value": "600mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "2-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 450, + "name": "Modafinil", + "aliases": [ + "alertec", + "modalert", + "modavigil", + "modiodal", + "provigil" + ], + "aliasesStr": "alertec,modalert,modavigil,modiodal,provigil", + "url": "https://psychonautwiki.org/wiki/Modafinil", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Modafinil.shtml", + "summary": "A wakefulness promoting, long acting stimulant which is typically only used functionally, because there is no real euphoric component to its effects. Also prescribed for daytime sleeping disorders.", + "reagents": null, + "classes": { + "chemical": [ + "Benzhydryl" + ], + "psychoactive": [ + "Eugeroic" + ] + }, + "toxicity": [ + "The median lethal dose at which 50% of participants die (LD50) from modafinil for human beings has never been reached" + ], + "addictionPotential": "not addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "benzhydryl", + "nootropic|nootropics" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "3.5 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 451, + "name": "Morpheridine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/morpheridine", + "experiencesUrl": null, + "summary": "Is a 4-Phenylpiperidine derivative that is related to Pehidine. It is roughly 4x as potent as the parent compound, does not cause convulsions such as Pethidine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg." + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-35mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Oral minutes" + }, + { + "name": "Duration", + "value": "Oral hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 452, + "name": "Morphine", + "aliases": [ + "mscontin", + "oramorph", + "sevredol", + "zomorph" + ], + "aliasesStr": "mscontin,oramorph,sevredol,zomorph", + "url": "https://psychonautwiki.org/wiki/Morphine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Morphine.shtml", + "summary": "The prototypical opioid drug, a powerful analgesic with euphoric qualities, found in the seeds and wax of the plant papaver somniferum (opium poppy). First isolated by Friedrich Sertürner in 1805, named for its sleep-inducing qualities. Do not combine with other depressants, may cause dangerous respiratory depression in overdose.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + } + ], + "bioavailability": "30%" + }, + { + "name": "Oral_IR", + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Oral_ER", + "duration": [ + { + "name": "Onset", + "value": "40-80 minutes" + }, + { + "name": "Duration", + "value": "4-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-5 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ], + "bioavailability": "15-20%" + }, + { + "name": "Plugged", + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "IV/IM", + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 453, + "name": "MPT", + "aliases": [ + "methylpropyltryptamine" + ], + "aliasesStr": "methylpropyltryptamine", + "url": "https://psychonautwiki.org/wiki/MPT", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "??? - ??? mg", + "note": "\"???\" is not a number." + } + ], + "duration": [ + { + "name": "Total", + "value": "??? - ???" + } + ] + } + ], + "interactions": null + }, + { + "id": 454, + "name": "MT-45", + "aliases": [ + "ic-6", + "mt45" + ], + "aliasesStr": "ic-6,mt45", + "url": "https://drugs.tripsit.me/mt-45", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_MT45.shtml", + "summary": "A synthetic opioid drug that was rumoured to be roughly 80% the potency of Morphine orally. Was created by Dainippon Pharmaceutical in the 1970's. It has been used as a lead compound for the design of related substances. It has been associated with hearing loss and hair loss. Structurally unrelated to most other opioid drugs. Treat with caution, especially long term use.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30mg" + }, + { + "name": "Light", + "value": "30-45mg" + }, + { + "name": "Common", + "value": "45-60mg" + }, + { + "name": "Strong", + "value": "60mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-45 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "2-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 455, + "name": "Mushrooms", + "aliases": [ + "mushroom", + "psilocybin", + "psylocybin", + "shrooms" + ], + "aliasesStr": "mushroom,psilocybin,psylocybin,shrooms", + "url": "https://drugs.tripsit.me/mushrooms", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Psilocybin.shtml", + "summary": "Fungi containing psilocybin, a prototypical psychedelic with similar effects to LSD, but with a shorter duration; also considered as being more confusing, introspective and entheogenic. Usually refers to psilocybe mushrooms rather than Amanitas, which have different effects. Are considered physically safe if properly identified, which should always be done by an expert.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1.5g" + }, + { + "name": "Common", + "value": "1.5-3.5g" + }, + { + "name": "Strong", + "value": "3.5g+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Varies" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Low Risk & Synergy", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Low Risk & Synergy", + "name": "5-MeO-xxT" + }, + { + "status": "Low Risk & Decrease", + "name": "Alcohol" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Caffeine" + }, + { + "status": "Caution", + "note": "Cannabis has an unexpectedly strong and somewhat unpredictable synergy with psychedelics.", + "name": "Cannabis" + }, + { + "status": "Caution", + "note": "Stimulants increase anxiety levels and the risk of thought loops which can lead to negative experiences", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Low Risk & Synergy", + "name": "DOx" + }, + { + "status": "Low Risk & Synergy", + "name": "DXM" + }, + { + "status": "Low Risk & Decrease", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Low Risk & Synergy", + "name": "MAOIs" + }, + { + "status": "Low Risk & Synergy", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Low Risk & No Synergy", + "name": "Opioids" + }, + { + "status": "Low Risk & Synergy", + "name": "PCP" + }, + { + "status": "Low Risk & Decrease", + "name": "SSRIs" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.", + "name": "Tramadol" + }, + { + "status": "Low Risk & Synergy", + "name": "aMT" + } + ] + }, + { + "id": 456, + "name": "MXiPr", + "aliases": [ + "mxip" + ], + "aliasesStr": "mxip", + "url": "https://psychonautwiki.org/wiki/MXiPr", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1.5 - 4 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 457, + "name": "MXM", + "aliases": [ + "methoxmetamine" + ], + "aliasesStr": "methoxmetamine", + "url": "https://drugs.tripsit.me/mxm", + "experiencesUrl": null, + "summary": "An arylcyclohexamine, dissociative and anaesthetic closely related to methoxetamine, ketamine and PCP. It has seen some popularity among RC users, being advertised as an MXE replacement after its illegalisation in many parts of the world - however, users report a more stimulating experience closer to those caused by PCP and its analogues.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10-20mg" + }, + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60-100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Varying hours" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 458, + "name": "Myristicin", + "aliases": [ + "nutmeg" + ], + "aliasesStr": "nutmeg", + "url": "https://psychonautwiki.org/wiki/Myristicin", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Phenylpropenes" + ], + "psychoactive": [ + "Deliriant" + ] + }, + "toxicity": [ + "is neurotoxic", + "can be fatal in extremely high doses" + ], + "addictionPotential": "is not known to be addictive", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50 - 200 mg" + }, + { + "name": "Common", + "value": "200 - 500 mg" + }, + { + "name": "Strong", + "value": "500 - 800 mg" + }, + { + "name": "Heavy", + "value": "800 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 72 hours" + }, + { + "name": "Onset", + "value": "3 - 8 hours" + }, + { + "name": "Come up", + "value": "1 - 4 hours" + }, + { + "name": "Peak", + "value": "9 - 12 hours" + }, + { + "name": "Offset", + "value": "12 - 48 hours" + }, + { + "name": "After effects", + "value": "24 - 72 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 459, + "name": "N-Acetylcysteine", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/N-Acetylcysteine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amino_acid", + "Cysteine" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": null, + "tolerance": { + "full": "develops quickly with repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100 mg" + }, + { + "name": "Light", + "value": "400 - 600 mg" + }, + { + "name": "Common", + "value": "600 - 1000 mg" + }, + { + "name": "Strong", + "value": "1000 - 1500 mg" + }, + { + "name": "Heavy", + "value": "1500 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + } + ], + "bioavailability": "4%" + } + ], + "interactions": null + }, + { + "id": 460, + "name": "Naloxone", + "aliases": [ + "evzio", + "narcan" + ], + "aliasesStr": "evzio,narcan", + "url": "https://psychonautwiki.org/wiki/Naloxone", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": null, + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Common", + "value": "1 - 4 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0 - 10 minutes" + } + ] + }, + { + "name": "Intramuscular", + "dosage": [ + { + "name": "Common", + "value": "0.4 - 2 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0.25 - 2 minutes" + } + ] + }, + { + "name": "Intravenous", + "dosage": [ + { + "name": "Common", + "value": "0.4 - 2 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "0.25 - 2 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 461, + "name": "Naphyrone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/naphyrone", + "experiencesUrl": null, + "summary": "A drug derived from pyrovalerone which acts as a TRI, producing stimulating effects. Had been sold in a blend called \"NRG-1\" Little information exists about the safety profile of this drug.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "(Tentative)", + "dosage": [ + { + "name": "Common", + "value": "20-35mg" + }, + { + "name": "Strong", + "value": "35-50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "Within minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 462, + "name": "Naproxen", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/naproxen", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Naproxen.shtml", + "summary": "A very common pain reliever/fever reducer also known as Aleve. Naproxen is in the same category as Ibuprofen, which is also a nonsteroidal anti-inflammatory. This drug is available in most places over the counter. Is sometimes used to reduce the body-load of certain drugs.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Common:", + "dosage": [ + { + "name": "Common", + "value": "250-500mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1" + }, + { + "name": "Duration", + "value": "4-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 463, + "name": "NEB", + "aliases": [ + "n-ethylbuphedrone" + ], + "aliasesStr": "n-ethylbuphedrone", + "url": "https://drugs.tripsit.me/neb", + "experiencesUrl": null, + "summary": "N-Ethylbuphedrone, an uncommon substituted cathinone. First appeared around 2011 but has not become popular. Effects should somewhat resemble other cathinones generally. Short-acting stimulating with more dopamine action than serotonin.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "30mg" + }, + { + "name": "Light", + "value": "30-50mg" + }, + { + "name": "Common", + "value": "50-80mg" + }, + { + "name": "Strong", + "value": "80-100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-30 minutes" + }, + { + "name": "Duration", + "value": "90-180 minutes" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-45mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "90-120 minutes" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 464, + "name": "Nefiracetam", + "aliases": [ + "nerfiracetam" + ], + "aliasesStr": "nerfiracetam", + "url": "https://drugs.tripsit.me/nefiracetam", + "experiencesUrl": null, + "summary": "Nootropic compound of the racetam family. Seems to enhance both GABAergic and cholinergic signalling. Long term use appears to be neuroprotective. Fat soluble.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Common:", + "dosage": [ + { + "name": "Common", + "value": "150-450mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 465, + "name": "Nicomorphine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/nicomorphine", + "experiencesUrl": null, + "summary": "Opioid agonist that is 2-3x the potency of Morphine. Is used in few countries. Rapid onset of effects, due to the increased lipid solubility.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Intravenously", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 466, + "name": "Nicotine", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Nicotine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Nicotine.shtml", + "summary": "A chemical found in tobacco, aubergines and tomatoes which is considered one of the most addictive drugs in existence. It is a mild stimulant, with stress relieving effects. It is widely used in the form of cigarettes, the use of which carries a high risk of causing cancer or heart issues over time. Increasingly, it is 'vaped' as a purportedly safer alternative to smoking.", + "reagents": null, + "classes": { + "chemical": [ + "Pyridine", + "Substituted_pyrrolidines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "rapidly develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "0.2 mg" + }, + { + "name": "Light", + "value": "0.3 - 0.8 mg" + }, + { + "name": "Common", + "value": "0.8 - 1.5 mg" + }, + { + "name": "Strong", + "value": "1.5 - 3.5 mg" + }, + { + "name": "Heavy", + "value": "3.5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 20 seconds" + }, + { + "name": "Come up", + "value": "5 - 10 seconds" + }, + { + "name": "Peak", + "value": "2 - 5 minutes" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Buccal", + "dosage": [ + { + "name": "Threshold", + "value": "" + }, + { + "name": "Light", + "value": "- mg" + }, + { + "name": "Common", + "value": "- mg" + }, + { + "name": "Strong", + "value": "- mg" + }, + { + "name": "Heavy", + "value": "mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "-" + }, + { + "name": "Onset", + "value": "-" + }, + { + "name": "Come up", + "value": "-" + }, + { + "name": "Peak", + "value": "-" + }, + { + "name": "Offset", + "value": "-" + }, + { + "name": "After effects", + "value": "-" + } + ] + } + ], + "interactions": null + }, + { + "id": 467, + "name": "Nifoxipam", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Nifoxipam", + "experiencesUrl": null, + "summary": "An uncommon and relatively new RC benzodiazepine, and metabolite of the hypnotic benzodiazepine flunitrazepam. Little information about the pharmacological properties of this drug exists. Likely to be a strong sedative and hypnotic.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.10 mg" + }, + { + "name": "Light", + "value": "0.25 - 0.5 mg" + }, + { + "name": "Common", + "value": "0.5 - 1 mg" + }, + { + "name": "Strong", + "value": "1 - 2 mg" + }, + { + "name": "Heavy", + "value": "2 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 75 hours" + }, + { + "name": "Onset", + "value": "45 - 120 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 468, + "name": "Nimetazepam", + "aliases": [ + "erimin" + ], + "aliasesStr": "erimin", + "url": "https://drugs.tripsit.me/nimetazepam", + "experiencesUrl": null, + "summary": "A pharmaceutical benzodiazepine with hypnotic and sedative effects. Rarely seen in the West but reportedly very frequently abused in Malaysia.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "12-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 469, + "name": "Nitemazepam", + "aliases": [ + "3-hydroxynimetazepam" + ], + "aliasesStr": "3-hydroxynimetazepam", + "url": "https://drugs.tripsit.me/nitemazepam", + "experiencesUrl": null, + "summary": "A new RC benzodiazepine based off the chemical structure of Nimetazepam. It is relatively new and not many experience reports exist on it. It is expected to feel similar to temazepam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "1-1.5mg" + }, + { + "name": "Common", + "value": "1.5-3mg" + }, + { + "name": "Strong", + "value": "3-5mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 470, + "name": "Nitracaine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/nitracaine", + "experiencesUrl": null, + "summary": "An analogue of dimethocaine with local anaesthetic and stimulant properties, marketed in the RC scene as a Cocaine replacement. Has not seen widespread popularity.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "100-150mg" + }, + { + "name": "Strong", + "value": "150-175mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "20-30mg" + }, + { + "name": "Common", + "value": "30-40mg" + }, + { + "name": "Strong", + "value": "50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 471, + "name": "Nitrazepam", + "aliases": [ + "baronite", + "dormin", + "dreem", + "enzed", + "gentravit", + "hypnonex", + "hypnoril", + "hypnotex", + "konit", + "mogadon", + "nicare", + "nigap", + "nipam", + "nirosun", + "nitavan", + "nithra" + ], + "aliasesStr": "baronite,dormin,dreem,enzed,gentravit,hypnonex,hypnoril,hypnotex,konit,mogadon,nicare,nigap,nipam,nirosun,nitavan,nithra", + "url": "https://drugs.tripsit.me/nitrazepam", + "experiencesUrl": null, + "summary": "Hypnotic Benzodiazepine, that is used for short term relief of anxiety and insomnia. It has a pronouced affect on respritory action.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-15mg" + }, + { + "name": "Strong", + "value": "15-20mg" + }, + { + "name": "Heavy", + "value": "20-30mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-40 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "6-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 472, + "name": "Nitrazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/nitrazolam", + "experiencesUrl": null, + "summary": "Hypnotic benzodiazepine that is the triazolo analogue of Nitrazepam and about 4x more potent compared to the parent compound. Also the dechlorinated derivative of Clonazolam with roughly 1/10 potency.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-3mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "2-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 473, + "name": "N2O", + "aliases": [ + "laughing_gas", + "n20", + "nos" + ], + "aliasesStr": "laughing_gas,n20,nos", + "url": "https://drugs.tripsit.me/nitrous", + "experiencesUrl": null, + "summary": "Nitrous oxide, also known as laughing gas, often inhaled through balloons filled with canisters of the gas.. A short-acting dissociative inhalant with strong visual, mental and auditory effects. Extremely popular especially in combination with other drugs.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": [ + { + "status": "Low Risk & Synergy", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Low Risk & Synergy", + "name": "5-MeO-xxT" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.", + "name": "Alcohol" + }, + { + "status": "Low Risk & Synergy", + "name": "Amphetamines" + }, + { + "status": "Low Risk & Decrease", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "name": "Cannabis" + }, + { + "status": "Low Risk & Synergy", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Low Risk & Synergy", + "name": "DOx" + }, + { + "status": "Low Risk & Synergy", + "name": "DXM" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Low Risk & No Synergy", + "name": "MAOIs" + }, + { + "status": "Low Risk & Synergy", + "name": "MDMA" + }, + { + "status": "Low Risk & Synergy", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Low Risk & Synergy", + "name": "NBOMes" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.", + "name": "Opioids" + }, + { + "status": "Low Risk & Synergy", + "name": "PCP" + }, + { + "status": "Low Risk & No Synergy", + "name": "SSRIs" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.", + "name": "Tramadol" + }, + { + "status": "Low Risk & Synergy", + "name": "aMT" + } + ] + }, + { + "id": 474, + "name": "NM-2-AI", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/NM-2-AI", + "experiencesUrl": null, + "summary": "Stimulant that is in the aminoindane class. Is it quite close to it's bigger brother 2-AI. Yet this has a lower potency, has a longer duration though.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Aminoindane" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 200 mg" + }, + { + "name": "Heavy", + "value": "200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 475, + "name": "Chloral hydrate", + "aliases": [ + "aquachloral", + "chloral-hydrate", + "somnos" + ], + "aliasesStr": "aquachloral,chloral-hydrate,somnos", + "url": "https://drugs.tripsit.me/noctec", + "experiencesUrl": null, + "summary": "Chloral Hydrate, a sedative drug discovered in 1832 with a history of recreational use going back to the 19th century. Sometimes prescribed for extreme insomnia. For such an old drug, relatively little is known about its long-term term effects on the body. Produces intoxication comparable to alcohol or benzodiazepines.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "200mg" + }, + { + "name": "Common", + "value": "200-500mg" + }, + { + "name": "Strong", + "value": "500-1000mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-60 minutes" + }, + { + "name": "Duration", + "value": "5-10 hours" + }, + { + "name": "After effects", + "value": "2-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 476, + "name": "Noopept", + "aliases": [ + "gvs-111", + "omberacetam", + "ноопепт" + ], + "aliasesStr": "gvs-111,omberacetam,ноопепт", + "url": "https://psychonautwiki.org/wiki/Omberacetam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Noopept_.shtml", + "summary": "A common nootropic often attributed with temporarily increasing intelligence, concentration, focus and memory recall. Daily use can lead to dependency with withdrawals which make the user feel 'stupid.' Often taken daily in a 'stack' with other nootropics.", + "reagents": null, + "classes": { + "chemical": [ + "Peptide" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "tolerance": { + "full": "develops over several weeks of prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "racetam", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 hours" + }, + { + "name": "Offset", + "value": "3 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "1 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 5 hours" + }, + { + "name": "Onset", + "value": "0 - 5 minutes" + }, + { + "name": "Peak", + "value": "2 hours" + }, + { + "name": "Offset", + "value": "3 hours" + } + ] + }, + { + "name": "Sublingual/Insufflated", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Sublingual", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Intranasal", + "duration": [ + { + "name": "Onset", + "value": "0-5 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 477, + "name": "Nordazepam", + "aliases": [ + "desmethyldiazepam", + "nordaz", + "nordiazepam" + ], + "aliasesStr": "desmethyldiazepam,nordaz,nordiazepam", + "url": "https://drugs.tripsit.me/nordazepam", + "experiencesUrl": null, + "summary": "Has all the normal benzodiazepine effects. Such as being an anti-convulsant, muscle relaxant, sedative effects, and anxiolytic. Active metabolite of Diazepam, Chlordiazepoxide, Clorazepate, among many others, which is where most of its effects come from. Has one of the longest lasting half-lifes in the class.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-15mg" + }, + { + "name": "Strong", + "value": "15-30mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-120 minutes" + }, + { + "name": "Duration", + "value": "10-20 hours" + }, + { + "name": "After effects", + "value": "1-120 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 478, + "name": "Norflurazepam", + "aliases": [ + "n-desalkylflurazepam" + ], + "aliasesStr": "n-desalkylflurazepam", + "url": "https://drugs.tripsit.me/norflurazepam", + "experiencesUrl": null, + "summary": "Benzodiazepine analogue that is an active metabolite to many other benzodiazepines, such as Flurazepam, Flutoprazepam, and Midazolam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-120 minutes" + }, + { + "name": "Duration", + "value": "10-16 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 479, + "name": "O-Desmethyltramadol", + "aliases": [ + "o-dsmt", + "o-smt", + "odt" + ], + "aliasesStr": "o-dsmt,o-smt,odt", + "url": "https://psychonautwiki.org/wiki/O-Desmethyltramadol", + "experiencesUrl": null, + "summary": "A opioid analgesic which is the main active metabolite of Tramadol. Alone, it is a few times more potent than Tramadol and has additional affinity for δ and κ-opioid receptors. Has proven popular when sold, but these occasions have been rare due to patent rights.", + "reagents": null, + "classes": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "moderate potential toxicity relative to its dose due to its potency", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Sublingual", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 50 mg" + }, + { + "name": "Strong", + "value": "50 - 80 mg" + }, + { + "name": "Heavy", + "value": "80 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 3 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "20 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 480, + "name": "O-PCE", + "aliases": [ + "2'-oxo-pce", + "2-oxo-pce", + "eticyclidone", + "opce" + ], + "aliasesStr": "2'-oxo-pce,2-oxo-pce,eticyclidone,opce", + "url": "https://psychonautwiki.org/wiki/O-PCE", + "experiencesUrl": null, + "summary": "Dissociative of the Arylcyclohexylamine class. Structurally related to Deschloroketamine.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "3 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 12 mg" + }, + { + "name": "Strong", + "value": "12 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 481, + "name": "Opium", + "aliases": [ + "o" + ], + "aliasesStr": "o", + "url": "https://drugs.tripsit.me/opium", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Opium.shtml", + "summary": "Opium is a naturally occurring analgesic harvested as a latex from ripe Papaver somniferum (opium poppy) pods. The sap of the poppy plant primarily contains codeine and morphine with the amounts varying by plant, which can be made into a tea and consumed raw, or further processed.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral_Tea", + "dosage": [ + { + "name": "Common", + "value": "333-500mg." + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Smoked", + "dosage": [ + { + "name": "Common", + "value": "100mg" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 482, + "name": "Oxazepam", + "aliases": [ + "serax" + ], + "aliasesStr": "serax", + "url": "https://drugs.tripsit.me/oxazepam", + "experiencesUrl": null, + "summary": "A prescription benzodiazepine with intermediate duration and half life. A sedative and hypnotic which may cause lowered inhibitions and amnesia in higher doses.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-30mg" + }, + { + "name": "Strong", + "value": "30-45mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-120 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 483, + "name": "Oxazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/oxazolam", + "experiencesUrl": null, + "summary": "A benzodiazepine derivative that is a prodrug for desmethyldiazepam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-15mg" + }, + { + "name": "Strong", + "value": "15-30mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-90 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "6-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 484, + "name": "Oxiracetam", + "aliases": [ + "hydroxypiracetam", + "neuractiv", + "neuromet" + ], + "aliasesStr": "hydroxypiracetam,neuractiv,neuromet", + "url": "https://psychonautwiki.org/wiki/Oxiracetam", + "experiencesUrl": null, + "summary": "Oxiracetam is a racetam nootropic, having a hydroxyl group being the only difference between this and Piracetam. It used as a nootropic, namely for increased cognitive function. It is usually used two to three times a day. This substance is normally taken with Choline, can cause headaches without the addition of Choline.", + "reagents": null, + "classes": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Stimulants", + "Nootropic" + ] + }, + "toxicity": [ + "safe even when high doses are consumed for a long period of time", + "exact toxic dosage is unknown" + ], + "addictionPotential": "non-addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "racetam", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "250 mg" + }, + { + "name": "Light", + "value": "500 - 1200 mg" + }, + { + "name": "Common", + "value": "1200 - 1800 mg" + }, + { + "name": "Strong", + "value": "1800 - 2400 mg" + }, + { + "name": "Heavy", + "value": "2400 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 485, + "name": "Oxycodone", + "aliases": [ + "codilek", + "endone", + "oxecta", + "oxy", + "oxycontin", + "oxydor", + "oxygesic", + "oxyir", + "oxynor", + "oxynorm", + "percocet", + "redocam", + "roxicodone" + ], + "aliasesStr": "codilek,endone,oxecta,oxy,oxycontin,oxydor,oxygesic,oxyir,oxynor,oxynorm,percocet,redocam,roxicodone", + "url": "https://psychonautwiki.org/wiki/Oxycodone", + "experiencesUrl": null, + "summary": "A semisynthetic opioid analgesic developed in 1917, prescribed primarily for pain management. It has become extremely popular as a recreational drug in some areas, and carries a high potential for addiction. Reported as being a little more 'stimulating' than other opioids.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2.5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + } + ], + "bioavailability": "60-87%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2.5 - 7.5 mg" + }, + { + "name": "Common", + "value": "7.5 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3 - 5 hours" + }, + { + "name": "Onset", + "value": "2 - 5 minutes" + } + ], + "bioavailability": "55-70%" + }, + { + "name": "Oral_IR", + "duration": [ + { + "name": "Onset", + "value": "20 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "Oral_ER", + "duration": [ + { + "name": "Onset", + "value": "40 minutes" + }, + { + "name": "Duration", + "value": "6-8 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + }, + { + "name": "IV", + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 486, + "name": "Oxymorphone", + "aliases": [ + "opana", + "stopsigns" + ], + "aliasesStr": "opana,stopsigns", + "url": "https://psychonautwiki.org/wiki/Oxymorphone", + "experiencesUrl": null, + "summary": "A powerful semisynthetic opioid analgesic also known as opana. A derivative of morphine it is approximately ten times as potent. Has a low oral bioavailability, and as such it is usually insufflated or taken rectally.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_morphinans" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2.5 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 30 mg" + }, + { + "name": "Heavy", + "value": "30 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + } + ], + "bioavailability": "10-20%" + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Common", + "value": "4-6mg" + }, + { + "name": "Heavy", + "value": "6-10mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Oral_IR", + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Oral_ER", + "duration": [ + { + "name": "Onset", + "value": "60-90 minutes" + }, + { + "name": "Duration", + "value": "6-14 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Plugged", + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-7 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "IV", + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 487, + "name": "Pagoclone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pagoclone", + "experiencesUrl": null, + "summary": "An anxiolytic drug related to zopiclone with no sedative or hypnotic qualities. Has been investigated as a possible alcohol replacement. Related in structure and effect to Zopiclone and Zolpidem.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 488, + "name": "Dextromoramide", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/palfium", + "experiencesUrl": null, + "summary": "Dextromoramide, a rare and powerful opioid analgesic approximately three times as potent as morphine with a shorter duration. Generally only seen in the Netherlands. Reported as having strange and rapid tolerance behaviour.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-7.5mg" + }, + { + "name": "Strong", + "value": "7.5-10mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Intravenously", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 489, + "name": "4-Fluorobutyrfentanyl", + "aliases": [ + "4-fbf", + "pfbf" + ], + "aliasesStr": "4-fbf,pfbf", + "url": "https://drugs.tripsit.me/parafluorobutyrfentanyl", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_4Fluorobutyrfentanyl.shtml", + "summary": "Rare, little known and extremely potent RC analogue of Fentanyl. This powerful opioid is generally only dispensed as a nasal spray. Handle with extreme caution and never mix with other depressants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "600-900ug" + }, + { + "name": "Strong", + "value": "900-1200ug." + } + ], + "duration": [ + { + "name": "Onset", + "value": "Insufflated minutes" + }, + { + "name": "Duration", + "value": "30-60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 490, + "name": "Parafluorofentanyl", + "aliases": [ + "4-fluorofentanyl", + "pff" + ], + "aliasesStr": "4-fluorofentanyl,pff", + "url": "https://drugs.tripsit.me/parafluorofentanyl", + "experiencesUrl": null, + "summary": "Rare, little known and extremely potent analogue of Fentanyl developed by Janssen Pharmaceutica in the 1960s. Use with extreme caution and never mix with other depressants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-25ug" + }, + { + "name": "Common", + "value": "25-40ug" + }, + { + "name": "Strong", + "value": "40-65ug+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + }, + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 491, + "name": "PARGY-LAD", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/PARGY-LAD", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "50 µg" + }, + { + "name": "Light", + "value": "125 - 275 µg" + }, + { + "name": "Common", + "value": "275 - 500 µg" + }, + { + "name": "Strong", + "value": "500 - 700 µg" + }, + { + "name": "Heavy", + "value": "700 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 492, + "name": "Paroxetine", + "aliases": [ + "paxil", + "seroxat" + ], + "aliasesStr": "paxil,seroxat", + "url": "https://drugs.tripsit.me/paroxetine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 493, + "name": "PCE", + "aliases": [ + "eticyclidine" + ], + "aliasesStr": "eticyclidine", + "url": "https://psychonautwiki.org/wiki/PCE", + "experiencesUrl": null, + "summary": "Eticyclidine (PCE) is a Dissociative anesthetic that has hallucinogenic effects. Slightly more potent than Phencyclidine.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": null, + "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "40 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "3 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 494, + "name": "PCP", + "aliases": [ + "angel", + "angel dust", + "angel_dust", + "angeldust", + "dust", + "phencyclidine", + "sernyl", + "sherman", + "wet" + ], + "aliasesStr": "angel,angel dust,angel_dust,angeldust,dust,phencyclidine,sernyl,sherman,wet", + "url": "https://psychonautwiki.org/wiki/PCP", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_PCP.shtml", + "summary": "A strong dissociative drug. PCP works primarily as an NMDA receptor antagonist. Also referred to as \"wet\" or \"angel dust\". Best known for stories of the strange and sometimes violent behaviour of those under its influence, though it is likely these are only in overdose cases.", + "reagents": null, + "classes": { + "chemical": [ + "Arylcyclohexylamines" + ], + "psychoactive": [ + "Dissociatives" + ] + }, + "toxicity": null, + "addictionPotential": "highly addictive with a high potential for adverse side effects such as psychosis", + "tolerance": { + "full": "with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dissociative|dissociatives" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 12 mg" + }, + { + "name": "Heavy", + "value": "12 mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "2 - 20 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "3 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "40 - 120 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 4 mg" + }, + { + "name": "Common", + "value": "4 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 15 mg" + }, + { + "name": "Heavy", + "value": "15mg+", + "note": "Heavy doses may result in psychosis and mania." + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "3 - 30 minutes" + }, + { + "name": "Come up", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 48 hours" + } + ] + } + ], + "interactions": [ + { + "status": "Dangerous", + "name": "2C-T-x" + }, + { + "status": "Low Risk & Synergy", + "name": "2C-x" + }, + { + "status": "Dangerous", + "name": "5-MeO-xxT" + }, + { + "status": "Unsafe", + "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.", + "name": "Alcohol" + }, + { + "status": "Unsafe", + "note": "This combination can easily lead to hypermanic states", + "name": "Amphetamines" + }, + { + "status": "Unsafe", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely", + "name": "Benzodiazepines" + }, + { + "status": "Caution", + "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "name": "Cannabis" + }, + { + "status": "Unsafe", + "note": "This combination can easily lead to hypermanic states", + "name": "Cocaine" + }, + { + "status": "Low Risk & Synergy", + "name": "DMT" + }, + { + "status": "Unsafe", + "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.", + "name": "DOx" + }, + { + "status": "Dangerous", + "name": "DXM" + }, + { + "status": "Dangerous", + "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.", + "name": "GHB/GBL" + }, + { + "status": "Low Risk & Synergy", + "name": "Ketamine" + }, + { + "status": "Low Risk & Synergy", + "name": "LSD" + }, + { + "status": "Dangerous", + "note": "This combination is very poorly explored", + "name": "MAOIs" + }, + { + "status": "Unsafe", + "note": "This combination can easily lead to hypermanic states", + "name": "MDMA" + }, + { + "status": "Caution", + "note": "There are no reports available about this combination", + "name": "MXE" + }, + { + "status": "Low Risk & Synergy", + "name": "Mescaline" + }, + { + "status": "Low Risk & Synergy", + "name": "Mushrooms" + }, + { + "status": "Low Risk & Synergy", + "name": "NBOMes" + }, + { + "status": "Low Risk & Synergy", + "name": "Nitrous" + }, + { + "status": "Caution", + "note": "PCP can reduce opioid tolerance, increasing the risk of overdose", + "name": "Opioids" + }, + { + "status": "Unsafe", + "note": "Details of this combination are not well understood but PCP generally interacts in an unpredictable manner.", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "name": "Tramadol" + }, + { + "status": "Dangerous", + "name": "aMT" + } + ] + }, + { + "id": 495, + "name": "Peganum harmala", + "aliases": [ + "esfand", + "espand", + "syrian rue" + ], + "aliasesStr": "esfand,espand,syrian rue", + "url": "https://psychonautwiki.org/wiki/Peganum_harmala", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 496, + "name": "Pemoline", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pemoline", + "experiencesUrl": null, + "summary": "A stimulant of the 4-oxazolidinone class. Was used as a medication for ADHD and Narcolepsy, yet was pulled from most markets due to liver failures among children.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Strong", + "value": "40-80mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 497, + "name": "Pentazocine", + "aliases": [ + "talwin" + ], + "aliasesStr": "talwin", + "url": "https://drugs.tripsit.me/pentazocine", + "experiencesUrl": null, + "summary": "A synthetic opioid used as an analgesic. It is only used IM and IV in the medical field and has respiratory depressant effects. It is pregnancy category C and schedule IV in the US.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "IM", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20mg-30mg" + }, + { + "name": "Strong", + "value": "30-60mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-20 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "IV", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "30mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "2-3 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 498, + "name": "Pentedrone", + "aliases": [ + "drone" + ], + "aliasesStr": "drone", + "url": "https://psychonautwiki.org/wiki/Pentedrone", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Pentedrone.shtml", + "summary": "A potent NDRI cathinone-type stimulant with more-ish effects but not thought to be especially enjoyable.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_cathinones" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 15 mg" + }, + { + "name": "Strong", + "value": "15 - 25 mg" + }, + { + "name": "Heavy", + "value": "25 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 10 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "2 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 10 mg" + }, + { + "name": "Strong", + "value": "10 - 20 mg" + }, + { + "name": "Heavy", + "value": "20 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 4 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 90 minutes" + }, + { + "name": "After effects", + "value": "1 - 8 hours" + } + ] + }, + { + "name": "Rectal", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 499, + "name": "Pentobarbital", + "aliases": [ + "nembutal", + "novopentobarb", + "pentobarbitone" + ], + "aliasesStr": "nembutal,novopentobarb,pentobarbitone", + "url": "https://psychonautwiki.org/wiki/Pentobarbital", + "experiencesUrl": null, + "summary": "A CNS depressant drug that is of the barbituate class. Typically not used often as it is easier to OD on than benzodiazepines, the new alternative to barbituates. Used often for insomnia, to cause sedation.", + "reagents": null, + "classes": { + "chemical": [ + "Barbiturates" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 200 mg" + }, + { + "name": "Strong", + "value": "200 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "1 - 36 hours" + } + ] + }, + { + "name": "IM", + "dosage": [ + { + "name": "Light", + "value": "100-150mg" + }, + { + "name": "Common", + "value": "150-200mg" + }, + { + "name": "Heavy", + "value": "200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-25 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-36 hours" + } + ] + }, + { + "name": "IV", + "dosage": [ + { + "name": "Light", + "value": "50-60mg" + }, + { + "name": "Common", + "value": "60-100mg" + }, + { + "name": "Heavy", + "value": "100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 minutes" + }, + { + "name": "Duration", + "value": "15-20 hours" + }, + { + "name": "After effects", + "value": "1-36 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 500, + "name": "Pentylone", + "aliases": [ + "4-meppp", + "bk-mbdp", + "bk-methyl-k" + ], + "aliasesStr": "4-meppp,bk-mbdp,bk-methyl-k", + "url": "https://drugs.tripsit.me/pentylone", + "experiencesUrl": null, + "summary": "A stimulant, empathogen and substituted cathinone. It was first synthesised in the 1960s, and re-appeared on the research chemical scene in 2010. Still, very little is known about the pharmacology or effects of this compound.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Strong", + "value": "40-80mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "10 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 501, + "name": "Peyote", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/peyote", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Peyote.shtml", + "summary": "Peyote is a small, spineless cactus that contains mescaline as its primary active chemical. It has a long history of use among the natives of northern Mexico and SW United States.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Fresh", + "dosage": [ + { + "name": "Light", + "value": "50-100g" + }, + { + "name": "Common", + "value": "100-150g" + }, + { + "name": "Heavy", + "value": "200g+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-120 minutes" + }, + { + "name": "Duration", + "value": "4-8" + }, + { + "name": "After effects", + "value": "6-8 hours" + } + ] + }, + { + "name": "Dried", + "dosage": [ + { + "name": "Light", + "value": "10-20g" + }, + { + "name": "Common", + "value": "20-30g" + }, + { + "name": "Strong", + "value": "30-40g" + }, + { + "name": "Heavy", + "value": "40g+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "60-120 minutes" + }, + { + "name": "Duration", + "value": "4-8" + }, + { + "name": "After effects", + "value": "6-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 502, + "name": "PFBT", + "aliases": [ + "4-fluorotropacocaine" + ], + "aliasesStr": "4-fluorotropacocaine", + "url": "https://drugs.tripsit.me/pfbt", + "experiencesUrl": null, + "summary": "Tropane derivative substance that supposedly has around ~30% the potency of Cocaine as a stimulant. While also having properties of a local anasthetic.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "10-20mg" + }, + { + "name": "Light", + "value": "20-50mg" + }, + { + "name": "Common", + "value": "50-70mg" + }, + { + "name": "Strong", + "value": "70-110mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-10 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 503, + "name": "Phenazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/phenazepam", + "experiencesUrl": null, + "summary": "A very long acting, potent and subtle benzodiazepine. Infamous for the calamitous experiences it tends to produce in people dosing unknown amounts. Prescribed in certain countries for epilepsy and alcohol withdrawal.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Heavy", + "value": "2-4mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-60 minutes" + }, + { + "name": "Duration", + "value": "18+ hours" + }, + { + "name": "After effects", + "value": "36+ hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 504, + "name": "Phenethylamine", + "aliases": [ + "pea" + ], + "aliasesStr": "pea", + "url": "https://drugs.tripsit.me/phenethylamine", + "experiencesUrl": null, + "summary": "Organic compound, which is a name of a class of chemicals that are quite well known for psychoactive and/or stimulant effects. Normally not used as a supplement as it is rapidly broken down into inactive compounds. Is found in many foods.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "300-500mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "1-4 hours" + }, + { + "name": "After effects", + "value": "10-60 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 505, + "name": "Phenetrazine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/phenetrazine", + "experiencesUrl": null, + "summary": "A rare phenethylamine stimulant related to 3-FPM. Virtually nothing is known about the pharmacology or effects of this compound but it is likely to have similar properties to other stimulants of its type. Not to be confused with phenmetrazine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5-10mg" + }, + { + "name": "Light", + "value": "10-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50-70mg." + }, + { + "name": "Heavy", + "value": "70mg+" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-35mg" + }, + { + "name": "Strong", + "value": "35-50mg" + }, + { + "name": "Heavy", + "value": "50mg+" + } + ] + } + ], + "interactions": null + }, + { + "id": 506, + "name": "Phenibut", + "aliases": [ + "fenibut", + "phenybut", + "phgaba" + ], + "aliasesStr": "fenibut,phenybut,phgaba", + "url": "https://psychonautwiki.org/wiki/Phenibut", + "experiencesUrl": null, + "summary": "A derivative of GABA with the addition of a phenyl ring which allows it to cross the Blood Brain Barrier. Is mostly used as an anti-anxiety and anti-insomnia medication. Tolerance and physical dependency builds very quickly.", + "reagents": null, + "classes": { + "chemical": [ + "Gabapentinoids" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol, benzodiazepines or opioids" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "GABA" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 g" + }, + { + "name": "Light", + "value": "0.5 - 1 g" + }, + { + "name": "Common", + "value": "1 - 2 g" + }, + { + "name": "Strong", + "value": "2 - 3.5 g" + }, + { + "name": "Heavy", + "value": "3.5 g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 16 hours" + }, + { + "name": "Onset", + "value": "1.5 - 3 hours" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + }, + { + "name": "Offset", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "6 - 24 hours" + } + ] + }, + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "300-600mg" + }, + { + "name": "Common", + "value": "600-1200mg" + }, + { + "name": "Strong", + "value": "1200-1800mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-120" + }, + { + "name": "Duration", + "value": "9-16 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 507, + "name": "Phenmetrazine", + "aliases": [ + "preludin" + ], + "aliasesStr": "preludin", + "url": "https://drugs.tripsit.me/phenmetrazine", + "experiencesUrl": null, + "summary": "Stimulant drug that was previously used as an appetite suppresant, has been withdrawn from the market, due to concerns of abuse and addiction. Usually produces less nervousness, euphoria, and insomnia than drugs of the amphetamine family. Also as a study concluded, it is slightly more effective than dextroamphetamine as a weight loss agent.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "25-50mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 508, + "name": "Phenobarbital", + "aliases": [ + "luminal", + "pheno", + "phenobarb", + "phenobarbitone" + ], + "aliasesStr": "luminal,pheno,phenobarb,phenobarbitone", + "url": "https://psychonautwiki.org/wiki/Phenobarbital", + "experiencesUrl": null, + "summary": "CNS depressant that is used mostly for insomnia (In older patients) and epliepsy (in younger patients) And it a very strong narcotic, that can be taken most ways. It's used less as \"safer\" alternatives have been made (Benzodiazepines).", + "reagents": null, + "classes": { + "chemical": [ + "Barbiturates" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "moderate toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "1 - 48 hours" + } + ] + }, + { + "name": "Intravenous", + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 509, + "name": "Phentermine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/phentermine", + "experiencesUrl": null, + "summary": "Psychostimulant of the substituted amphetamine class. Used in medicine as an appetite suppressant.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Strong", + "value": "40-70mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 510, + "name": "Picamilon", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/picamilon", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Picamilon.shtml", + "summary": "An analogue of GABA that does pass the brain blood barrier, which is then hydrolyzed into GABA and Niacin. In which the GABA could produce an anxiolytic effect. The Niacin as a vasodilator. And is usually used as part of a nootropic stack.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "40-80mg" + }, + { + "name": "Common", + "value": "80-140mg" + }, + { + "name": "Strong", + "value": "140-250mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 511, + "name": "Pinazepam", + "aliases": [ + "domar" + ], + "aliasesStr": "domar", + "url": "https://drugs.tripsit.me/pinazepam", + "experiencesUrl": null, + "summary": "Benzodiazepine that is solely an anxiolytic drug that lacks the hypnotic and motor impairment that most benzodiazepines do. The main metabolite of this is Nordazepam and to a lesser effect Oxazepam, which is where it gets most of its effects", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-90 minutes" + }, + { + "name": "Duration", + "value": "6-16 hours" + }, + { + "name": "After effects", + "value": "2-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 512, + "name": "Piper nigrum (botany)", + "aliases": [ + "black pepper", + "green pepper", + "peppercorn", + "white pepper" + ], + "aliasesStr": "black pepper,green pepper,peppercorn,white pepper", + "url": "https://psychonautwiki.org/wiki/Piper_nigrum_(botany)", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 513, + "name": "PiPT", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pipt", + "experiencesUrl": null, + "summary": "A rare psychedelic tryptamine related to DPT. Little is known about the effects or safety profile of this compound.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Vapourized", + "dosage": [ + { + "name": "Threshold", + "value": "10mg" + }, + { + "name": "Light", + "value": "15mg" + }, + { + "name": "Common", + "value": "15-20mg" + }, + { + "name": "Heavy", + "value": "20mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Vaped", + "duration": [ + { + "name": "Onset", + "value": "5 minutes" + }, + { + "name": "Duration", + "value": "2 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "1 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 514, + "name": "Piracetam", + "aliases": [ + "biotropil", + "breinox", + "geratam", + "lucetam", + "noostan", + "nootropil", + "oikamid" + ], + "aliasesStr": "biotropil,breinox,geratam,lucetam,noostan,nootropil,oikamid", + "url": "https://psychonautwiki.org/wiki/Piracetam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Piracetam.shtml", + "summary": "A racetam nootropic claimed by many to have cognitive benefits however this has never been strongly supported in healthy individuals. Prescribed in the UK as a treatment for myoclonus. Potentially an ampakine. One of the first popular 'nootropics.'", + "reagents": null, + "classes": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": null, + "addictionPotential": "not addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "racetam", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 - 0.5g" + }, + { + "name": "Light", + "value": "0.5 - 2g" + }, + { + "name": "Common", + "value": "2 - 3g" + }, + { + "name": "Strong", + "value": "3 - 5g" + }, + { + "name": "Heavy", + "value": "5g +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + }, + { + "name": "Common:", + "dosage": [ + { + "name": "Common", + "value": "1200-4800mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-35 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 515, + "name": "Ethchlorvynol", + "aliases": [ + "ethchlorvnol", + "placidyl" + ], + "aliasesStr": "ethchlorvnol,placidyl", + "url": "https://drugs.tripsit.me/placdyl", + "experiencesUrl": null, + "summary": "Sedative Hypnotic medication made in the 50's. It was used for short term help for insomnia (No longer than two weeks)", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "100-200mg" + }, + { + "name": "Common", + "value": "200-500mg" + }, + { + "name": "Strong", + "value": "500-750mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "6-9 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 516, + "name": "PMA", + "aliases": [ + "4-ma", + "death" + ], + "aliasesStr": "4-ma,death", + "url": "https://psychonautwiki.org/wiki/PMA", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_PMA.shtml", + "summary": "An empathogen with a slow onset and very strong serotonin release. This, combined with its lack of dopamine release, often leads users to dose more for the pleasurable effects which never come, leading to hospitalisations and deaths. Sometimes mis-sold as MDMA.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "toxicity": [ + "can be considered extremely toxic when compared to other substances such as Methamphetamine or MDMA", + "Ingestion of PMA has been associated with severe tachycardia (abnormally high heart rate), seizures, hyperthermia, and death" + ], + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "< 10 mg" + }, + { + "name": "Light", + "value": "20 - 40 mg" + }, + { + "name": "Common", + "value": "40 - 60 mg" + }, + { + "name": "Strong", + "value": null, + "note": "Higher dosages can result in serious hyperthermia and eventually death." + } + ], + "duration": [ + { + "name": "Total", + "value": "short" + } + ] + } + ], + "interactions": null + }, + { + "id": 517, + "name": "PMMA", + "aliases": [ + "4-mma", + "pma" + ], + "aliasesStr": "4-mma,pma", + "url": "https://psychonautwiki.org/wiki/PMMA", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Entactogens" + ] + }, + "toxicity": [ + "can be considered extremely toxic when compared to other substances such as Methamphetamine or MDMA", + "Ingestion of PMMA has been associated with severe tachycardia (abnormally high heart rate), seizures, hyperthermia, and death" + ], + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "100 - 120 mg" + }, + { + "name": "Strong", + "value": null, + "note": "Higher dosages can result in serious hyperthermia and eventually death." + } + ], + "duration": [ + { + "name": "Total", + "value": "short" + } + ] + } + ], + "interactions": null + }, + { + "id": 518, + "name": "Pramiracetam", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Pramiracetam", + "experiencesUrl": null, + "summary": "A CNS stimulant that is a nootropic, that belongs to the racetam family of compounds. Much more potent than Piracetam while appearing to work on similar mechanisms.", + "reagents": null, + "classes": { + "chemical": [ + "Racetams" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "not addictive with a low potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "racetam", + "nootropic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "100 mg" + }, + { + "name": "Light", + "value": "250 - 500 mg" + }, + { + "name": "Common", + "value": "500 - 800 mg" + }, + { + "name": "Strong", + "value": "800 - 1200 mg" + }, + { + "name": "Heavy", + "value": "1200 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 7 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + } + ] + }, + { + "name": "Common:", + "dosage": [ + { + "name": "Common", + "value": "400-1200mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 519, + "name": "Prazepam", + "aliases": [ + "centrac", + "centrax", + "demetrin", + "lysanxia", + "pozapam", + "prasepine", + "prazene", + "reapam", + "trepidan" + ], + "aliasesStr": "centrac,centrax,demetrin,lysanxia,pozapam,prasepine,prazene,reapam,trepidan", + "url": "https://drugs.tripsit.me/prazepam", + "experiencesUrl": null, + "summary": "Benzodiazepine dervative. Has all the normal benzodiazepine-like quality (Anxiolytic/anticonvulsant/sedative/Skeletal muscle relaxant) It is also a prodrug for Desmethyldiazepam which is responsible for most if not all of the effects of Prazepam.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-20mg" + }, + { + "name": "Strong", + "value": "20-40mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-120 minutes" + }, + { + "name": "Duration", + "value": "8-20 hours" + }, + { + "name": "After effects", + "value": "8-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 520, + "name": "PRE-084", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pre-084", + "experiencesUrl": null, + "summary": "A sigma-1 receptor agonist derived structurally from PCP. It has cognitive enhancing effects as well as antidepressant effects, and shows promise in treating many nervous system diseases such as ALS and parkinsons.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 521, + "name": "Pregabalin", + "aliases": [ + "lyrica", + "pregablin" + ], + "aliasesStr": "lyrica,pregablin", + "url": "https://drugs.tripsit.me/pregabalin", + "experiencesUrl": null, + "summary": "Pregabalin (Lyrica) is a GABA derivative that is used to treat neuropathic pain and seizures, as well as anxiety.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "150-300mg" + }, + { + "name": "Common", + "value": "300-600mg" + }, + { + "name": "Strong", + "value": "600-900mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "90-150 minutes" + }, + { + "name": "Duration", + "value": "6-14 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 522, + "name": "PRL-8-53", + "aliases": [ + "prl853" + ], + "aliasesStr": "prl853", + "url": "https://drugs.tripsit.me/prl-8-53", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_PRL853.shtml", + "summary": "A nootropic research chemical first synthesized in the 70s. One study shows a drastic improvement in mid-term memory among users, but otherwise it is severely lacking in information surrounding it. It has no recreational potential.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Threshold:", + "dosage": [ + { + "name": "Threshold", + "value": "2-3mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "Within minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Sublingual", + "duration": [ + { + "name": "Onset", + "value": "Within minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Intranasally", + "duration": [ + { + "name": "Onset", + "value": "Within minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 523, + "name": "PRO-LAD", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/PRO-LAD", + "experiencesUrl": null, + "summary": "A very rare lysergamide that is slightly less potent than LSD, yet with a shorter duration of action.", + "reagents": null, + "classes": { + "chemical": [ + "Lysergamides" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "5-7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 µg" + }, + { + "name": "Light", + "value": "50 - 100 µg" + }, + { + "name": "Common", + "value": "100 - 200 µg" + }, + { + "name": "Strong", + "value": "200 - 350 µg" + }, + { + "name": "Heavy", + "value": "350 µg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 524, + "name": "Prochlorperazine", + "aliases": [ + "buccastem", + "compazine", + "phenotil", + "stemetil", + "stemzine" + ], + "aliasesStr": "buccastem,compazine,phenotil,stemetil,stemzine", + "url": "https://psychonautwiki.org/wiki/Prochlorperazine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Phenothiazine" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "2.5 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 20 mg" + }, + { + "name": "Strong", + "value": "20 - 40 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "30 - 45 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 525, + "name": "Prolintane", + "aliases": [ + "catovit", + "promotil", + "villescon" + ], + "aliasesStr": "catovit,promotil,villescon", + "url": "https://psychonautwiki.org/wiki/Prolintane", + "experiencesUrl": null, + "summary": "A stimulant drug which is a dopamine reuptake inhibitor, related to MDPV and Pyrovalerone. It was first developed in the 1950s, and has seen some light usage in rave culture, though it remains relatively uncommon. Believed to have a relatively forgiving safety profile.", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_pyrrolidines", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "15 - 25 mg" + }, + { + "name": "Common", + "value": "25 - 45 mg" + }, + { + "name": "Strong", + "value": "45 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Come up", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 526, + "name": "Promethazine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/promethazine", + "experiencesUrl": null, + "summary": "A first generation antihistamine, which also possesses anticholinergic, strong sedative and antipsychotic properties. Once commonly used as a treatment for psychosis, it is now more commonly seen as a component of codeine cough syrups as an anti-nausea agent.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Common:", + "dosage": [ + { + "name": "Common", + "value": "25-75mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "0-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 527, + "name": "Propofol", + "aliases": [ + "diprivan", + "milk-of-amnesia" + ], + "aliasesStr": "diprivan,milk-of-amnesia", + "url": "https://drugs.tripsit.me/propofol", + "experiencesUrl": null, + "summary": "A very short acting sedative that is usually given at the start of general anesthesia, and for maintenance of the prior. It should never be used outside of a medical setting. With that in mind, if you do plan to use this drug recreational, please have a very experienced friend with you that has the skills to insert a cannula, and monitor you very closely.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Intravenously", + "dosage": [ + { + "name": "Light", + "value": "10-30mg" + }, + { + "name": "Common", + "value": "30-60mg" + }, + { + "name": "Strong", + "value": "60-100mg" + } + ] + }, + { + "name": "Intravenous", + "duration": [ + { + "name": "Onset", + "value": "0-2 minutes" + }, + { + "name": "Duration", + "value": "10-20 minutes" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 528, + "name": "Propoxyphene", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/propoxyphene", + "experiencesUrl": null, + "summary": "Is an analgesic in the opioid family. It is intended for mild pain and for its antitussive effects. Has been taken off the market in Europe and the US due to concerns of fatal overdoses and heart arrhythmias.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "30-65mg" + }, + { + "name": "Common", + "value": "65-100" + }, + { + "name": "Strong", + "value": "100-200mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-30 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "2-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 529, + "name": "Propranolol", + "aliases": [ + "hemangeol", + "inderal", + "innopran" + ], + "aliasesStr": "hemangeol,inderal,innopran", + "url": "https://drugs.tripsit.me/propranolol", + "experiencesUrl": null, + "summary": "Is a nonselective beta blocker. It is used in medication for high blood pressure, anxiety, and tremors. Also fun fact, it was the first successful beta-blocker developed.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-30mg" + }, + { + "name": "Common", + "value": "40-80mg" + }, + { + "name": "Strong", + "value": "80-140mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "3-7 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 530, + "name": "Propylhexedrine", + "aliases": [ + "benzedrex", + "hexahdromethamphetamine", + "propylhexadrine" + ], + "aliasesStr": "benzedrex,hexahdromethamphetamine,propylhexadrine", + "url": "https://psychonautwiki.org/wiki/Propylhexedrine", + "experiencesUrl": null, + "summary": "A relatively common CNS stimulant sold over the counter in benzedrex inhalers.", + "reagents": null, + "classes": { + "chemical": [ + "Cycloalkylamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": { + "full": "rapidly develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "dopamine", + "stimulant" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "31.25 - 62.5 mg" + }, + { + "name": "Common", + "value": "62.5 - 125 mg" + }, + { + "name": "Strong", + "value": "125 - 187.5 mg" + }, + { + "name": "Heavy", + "value": "187.5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 10 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Come up", + "value": "15 - 90 minutes" + }, + { + "name": "Peak", + "value": "2 - 5 hours" + }, + { + "name": "Offset", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "2 - 12 hours" + } + ] + }, + { + "name": "Oral(Pure)", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-50mg" + }, + { + "name": "Strong", + "value": "50mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + }, + { + "name": "Insufflated(Pure)", + "dosage": [ + { + "name": "Light", + "value": "5-15mg" + }, + { + "name": "Common", + "value": "15-30mg" + }, + { + "name": "Strong", + "value": "30-50mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + }, + { + "name": "Oral(Benzedrex)", + "dosage": [ + { + "name": "Light", + "value": "20-60mg" + }, + { + "name": "Common", + "value": "60-125mg" + }, + { + "name": "Strong", + "value": "125-250mg" + }, + { + "name": "Heavy", + "value": "250mg+" + } + ], + "duration": [ + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-30mg" + }, + { + "name": "Common", + "value": "30-75mg" + }, + { + "name": "Strong", + "value": "75-100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "4-8 hours" + }, + { + "name": "After effects", + "value": "1-16 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 531, + "name": "Propylphenidate", + "aliases": [ + "pph" + ], + "aliasesStr": "pph", + "url": "https://drugs.tripsit.me/propylphenidate", + "experiencesUrl": null, + "summary": "Propylphenidate is a short acting stimulant.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "15-25mg" + }, + { + "name": "Common", + "value": "25-60mg" + }, + { + "name": "Strong", + "value": "60-100mg" + }, + { + "name": "Heavy", + "value": "100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-25 minutes" + }, + { + "name": "Duration", + "value": "1.5-3 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 532, + "name": "Proscaline", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Proscaline", + "experiencesUrl": null, + "summary": "A very uncommon psychedelic stimulant and phenethylamine and analogue on mescaline with similar effects. Roughly 5-7 times more potent than mescaline by weight.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "no negative health effects attributed to trying this drug" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "15 - 30 mg" + }, + { + "name": "Common", + "value": "30 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "After effects", + "value": "3 - 5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 533, + "name": "Pseudoephrine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pseudoephedrine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Pseudoephedrine.shtml", + "summary": "Widely sold as a decongestant, and one isomer of Ephedrine. It is not generally considered to have any recreational value. Is also used in the synthesis of Methcathinone and Methamphetamine.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "30-60mg." + }, + { + "name": "Common", + "value": "60-90mg." + }, + { + "name": "Strong", + "value": "90-120mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-90 minutes" + }, + { + "name": "Duration", + "value": "2-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 534, + "name": "Psilocin", + "aliases": [ + "4-ho-dmt", + "4-oh-dmt", + "psilocine", + "psilocyn", + "psilotsin" + ], + "aliasesStr": "4-ho-dmt,4-oh-dmt,psilocine,psilocyn,psilotsin", + "url": "https://psychonautwiki.org/wiki/Psilocin", + "experiencesUrl": null, + "summary": "Psilocin is a substutued tryptamine alkaloid, that is present in most psychedelic mushrooms. It is relatively unstable in solution due to the -OH group.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_tryptamines" + ], + "psychoactive": [ + "Psychedelics" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 15 mg" + }, + { + "name": "Common", + "value": "15 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 6 hours" + }, + { + "name": "Onset", + "value": "20 - 45 minutes" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "2 - 3 hours" + }, + { + "name": "Offset", + "value": "1.5 - 2 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "3-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 535, + "name": "Psilocybe cubensis", + "aliases": [ + "magic mushroom", + "shrooms" + ], + "aliasesStr": "magic mushroom,shrooms", + "url": "https://psychonautwiki.org/wiki/Psilocybe_cubensis", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 536, + "name": "PST", + "aliases": [ + "poppy-seed-tea", + "poppy-tea" + ], + "aliasesStr": "poppy-seed-tea,poppy-tea", + "url": "https://drugs.tripsit.me/pst", + "experiencesUrl": null, + "summary": "Poppy Tea can be made from poppy pods, stalks and seeds, and contains various opium alkaloids including primarily Morphine, as well as Codeine and others. There is great variation in Poppy Tea potency and therefor doses are indicated for opioid naive users.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "duration": [ + { + "name": "Duration", + "value": "8-24 hours" + }, + { + "name": "After effects", + "value": "1-30 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 537, + "name": "PV-10", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pv-10", + "experiencesUrl": null, + "summary": "Inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 538, + "name": "PV-8", + "aliases": [ + "a-phpp" + ], + "aliasesStr": "a-phpp", + "url": "https://drugs.tripsit.me/pv-8", + "experiencesUrl": null, + "summary": "Stimulant of the pyrrolidinophenone class that is a higher homologue of α-PHP and generally less potent and less effective.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-20mg" + }, + { + "name": "Common", + "value": "20-40mg" + }, + { + "name": "Strong", + "value": "40-60mg" + }, + { + "name": "Heavy", + "value": "60+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "6-12 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "4-8 hours" + } + ] + }, + { + "name": "Vapourized", + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "0.5-1.5 hours" + }, + { + "name": "After effects", + "value": "2-5 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 539, + "name": "PV-9", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pv-9", + "experiencesUrl": null, + "summary": "Inactive.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 540, + "name": "Pyrazolam", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/Pyrazolam", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Pyrazolam.shtml", + "summary": "RC benzodiazepine discovered by Hoffman-LaRoche in the 1970s. Came to the RC market in the early 2010s. At lower doses it is mainly an anxiolytic compound, yet at higher doses can be quite sedating, hypnotic, amnesic, and can cause loss of inhibitions. Structurally similar to Alprazolam, Bromazepam, and Triazolam. Is 12x as potent as Diazepam.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.5 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "5 - 8 hours" + }, + { + "name": "Onset", + "value": "10 - 15 minutes" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 541, + "name": "Pyrophenidone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/pyrophenidone", + "experiencesUrl": null, + "summary": "An NDRI pyrovalerone derivative reported to have very similar subjective effects. Virtually no information exists about this drug's effects in humans.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Vaporized", + "dosage": [ + { + "name": "Light", + "value": "5-10mg" + }, + { + "name": "Common", + "value": "10-25mg" + }, + { + "name": "Strong", + "value": "25-50mg" + }, + { + "name": "Heavy", + "value": "50mg+." + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-30 minutes" + }, + { + "name": "Duration", + "value": "1-1.5 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "20-40mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60-90mg" + }, + { + "name": "Heavy", + "value": "90mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "1-3 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 542, + "name": "Quazepam", + "aliases": [ + "doral" + ], + "aliasesStr": "doral", + "url": "https://drugs.tripsit.me/quazepam", + "experiencesUrl": null, + "summary": "Benzodiazepine derivate drug, noral is prescribed for short term treatment of insomnia, and sleep maintenance. its MOA is very similar to Ambien and Sonata and substitutes for those in animal studies.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "7.5-10mg" + }, + { + "name": "Common", + "value": "10-15mg." + }, + { + "name": "Strong", + "value": "15-30mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ], + "bioavailability": "29-35%" + } + ], + "interactions": null + }, + { + "id": 543, + "name": "Quetiapine", + "aliases": [ + "seroquel" + ], + "aliasesStr": "seroquel", + "url": "https://psychonautwiki.org/wiki/Quetiapine", + "experiencesUrl": null, + "summary": "An atypical antipsychotic medication under the brand name Seroquel. Also used to treat insomnia and mood swings. This drug is very sedating and can stop/slow down psychedelic drug trips. Infrequently abused.", + "reagents": null, + "classes": { + "chemical": [ + "Dibenzothiazepine" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "toxicity": [ + "low toxicity" + ], + "addictionPotential": "moderately physically and psychologically addictive", + "tolerance": { + "full": "within a week of continuous use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "10 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "4 - 8 hours" + }, + { + "name": "Onset", + "value": "20 - 40 minutes" + }, + { + "name": "Peak", + "value": "1.5 - 6 hours" + }, + { + "name": "Offset", + "value": "6 - 7 hours" + }, + { + "name": "After effects", + "value": "24 - 48 hours" + } + ], + "bioavailability": "100% - 100%" + } + ], + "interactions": null + }, + { + "id": 544, + "name": "Rilmazafone", + "aliases": [ + "rhythmy" + ], + "aliasesStr": "rhythmy", + "url": "https://drugs.tripsit.me/rilmazafone", + "experiencesUrl": null, + "summary": "Unique to Japan, this drug, also known as Rhythmy, is a benzodiazepine pro-drug which while inactive itself, is metabolised into the active compound in-vivo. Soluble in water.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": ".5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "6-8 hours" + }, + { + "name": "After effects", + "value": "6-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 545, + "name": "Risperidone", + "aliases": [ + "risperdal" + ], + "aliasesStr": "risperdal", + "url": "https://psychonautwiki.org/wiki/Risperidone", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Benzisoxazole" + ], + "psychoactive": [ + "Antipsychotic" + ] + }, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "0.25 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 6 mg" + }, + { + "name": "Heavy", + "value": "6 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "12 - 20 hours" + }, + { + "name": "Onset", + "value": "20 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 8 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "12 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 546, + "name": "Rolicyclidine", + "aliases": [ + "pcpy" + ], + "aliasesStr": "pcpy", + "url": "https://drugs.tripsit.me/rolicyclidine", + "experiencesUrl": null, + "summary": "Rolicyclidine, also known as PCPy, is a dissociative with effects similar to PCP. While this dissociative anesthetic has hallucinogenic and sedative effects, it is said to be much less stimulating than PCP. In this sense it is more similar to opioids, or other central nervous system depressants.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2-4mg" + }, + { + "name": "Common", + "value": "4-8mg" + }, + { + "name": "Strong", + "value": "8mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "2-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + }, + { + "name": "Nasal", + "duration": [ + { + "name": "Onset", + "value": "30 minutes" + }, + { + "name": "Duration", + "value": "2-6 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 547, + "name": "Ronlax", + "aliases": [ + "ethyl-loflazepate", + "meilax", + "victan" + ], + "aliasesStr": "ethyl-loflazepate,meilax,victan", + "url": "https://drugs.tripsit.me/ronlax", + "experiencesUrl": null, + "summary": "A benzodiazepine derivative that posses the standard benzodiazepine effects. It has a very long half life (51-103 hours) it metabolizes into an active compound. (Descarboxyloflazepate) Is sold in Mexico.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.5-1mg" + }, + { + "name": "Common", + "value": "1-2mg" + }, + { + "name": "Strong", + "value": "2-4mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "45-90 minutes" + }, + { + "name": "Duration", + "value": "8-16 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 548, + "name": "Salvia", + "aliases": [ + "sage of the diviners", + "sally", + "salvia divinorum", + "seer's sage", + "ska maría pastora", + "yerba de la pastora" + ], + "aliasesStr": "sage of the diviners,sally,salvia divinorum,seer's sage,ska maría pastora,yerba de la pastora", + "url": "https://psychonautwiki.org/wiki/Salvia_divinorum", + "experiencesUrl": null, + "summary": "A plant which, when smoked, causes short but very intense psychedelic experiences. It is considered physically safe, though users of high dosages often experience bizarre other-worldly scenarios which may be confusing or terrifying.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Sublingual", + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "30-60 minutes" + }, + { + "name": "After effects", + "value": "15-20 minutes" + } + ] + }, + { + "name": "Smoked", + "duration": [ + { + "name": "Onset", + "value": "0-2 minutes" + }, + { + "name": "Duration", + "value": "5-30 minutes" + }, + { + "name": "After effects", + "value": "15-20 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 549, + "name": "Salvinorin A", + "aliases": [ + "diviner's sage", + "sally", + "salvia", + "salvia divinorum", + "seer's sage", + "ska maría pastora" + ], + "aliasesStr": "diviner's sage,sally,salvia,salvia divinorum,seer's sage,ska maría pastora", + "url": "https://psychonautwiki.org/wiki/Salvinorin_A", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Terpenoid", + "Salvinorin" + ], + "psychoactive": [ + "Hallucinogens" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": null, + "crossTolerances": [ + "hallucinogen" + ], + "roas": [ + { + "name": "Smoked", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "15 - 90 minutes" + }, + { + "name": "Onset", + "value": "15 - 60 seconds" + }, + { + "name": "After effects", + "value": "15 - 60 minutes" + } + ] + }, + { + "name": "Sublingual", + "dosage": null, + "duration": [ + { + "name": "Total", + "value": "30 - 90 minutes" + }, + { + "name": "Onset", + "value": "10 - 20 minutes" + }, + { + "name": "After effects", + "value": "30 - 120 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 550, + "name": "SAM-e", + "aliases": [ + "methylguanidoacetic acid", + "s-adenosyl methionine" + ], + "aliasesStr": "methylguanidoacetic acid,s-adenosyl methionine", + "url": "https://psychonautwiki.org/wiki/SAM-e", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Nitrogenous_organic_acid" + ], + "psychoactive": [ + "Nootropic" + ] + }, + "toxicity": null, + "addictionPotential": "not habit-forming with a low potential for abuse", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "200 mg" + }, + { + "name": "Light", + "value": "400 - 800 mg" + }, + { + "name": "Common", + "value": "800 - 1200 mg" + }, + { + "name": "Strong", + "value": "1200 - 1600 mg" + }, + { + "name": "Heavy", + "value": "1600 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "100 - 180 minutes" + } + ], + "bioavailability": "2-10%" + } + ], + "interactions": null + }, + { + "id": 551, + "name": "Scopolamine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/scopolamine", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Scopolamine.shtml", + "summary": "The main active compound in datura, medium and high doses have serious side effects and cause extremely unpleasant deleriant hallucinations. Avoid it.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 552, + "name": "Secobarbital", + "aliases": [ + "secobarbitone", + "seconal" + ], + "aliasesStr": "secobarbitone,seconal", + "url": "https://psychonautwiki.org/wiki/Secobarbital", + "experiencesUrl": null, + "summary": "A Barbiturate derivative that possesses all the classic effects of todays Benzodiazepines, and the old Barbiturates. It's used in the treatment of Epilepsy, short term treatment for insomnia, and a preoperative medication for anaesthesia and anxiolysis for short surgical/diagnostic/therapeutic procedures.", + "reagents": null, + "classes": { + "chemical": [ + "Barbiturates" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "moderate toxicity" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "20 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Peak", + "value": "4 - 8 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "1 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 553, + "name": "Sertraline", + "aliases": [ + "lustral", + "zoloft" + ], + "aliasesStr": "lustral,zoloft", + "url": "https://drugs.tripsit.me/sertraline", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 554, + "name": "Sinicuichi", + "aliases": [ + "heimia-salicifolia", + "shrubby-yellowcrest", + "sini", + "sun-opener", + "willow-leaf-heimia" + ], + "aliasesStr": "heimia-salicifolia,shrubby-yellowcrest,sini,sun-opener,willow-leaf-heimia", + "url": "https://drugs.tripsit.me/sinicuichi", + "experiencesUrl": null, + "summary": "A perennial shrub with small narrow leaves and yellow flowers growing up to ~1.5 meters. Known under many different names. Has been used for Shamanic purposes by natives in Central America and Mexico. Mostly auditory based.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 555, + "name": "Sonata", + "aliases": [ + "zaleplon" + ], + "aliasesStr": "zaleplon", + "url": "https://drugs.tripsit.me/sonata", + "experiencesUrl": null, + "summary": "Sedative-Hypnotic of the nonbenzodiazepine from the Pyrazolopyramide class. It is used mostly for short term insomnia.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 556, + "name": "STS-135", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/STS-135", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Adamantanes", + "Indolecarboxamide" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "cannabinoids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1.5 mg" + }, + { + "name": "Common", + "value": "1.5 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 4 mg" + }, + { + "name": "Heavy", + "value": "4 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "30 - 60 minutes" + }, + { + "name": "Onset", + "value": "10 - 45 seconds" + }, + { + "name": "Come up", + "value": "10 - 45 minutes" + }, + { + "name": "Peak", + "value": "10 - 30 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "15 - 45 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 557, + "name": "Sufentanil", + "aliases": [ + "chronogesic,", + "sufenta", + "sufentanyl" + ], + "aliasesStr": "chronogesic,,sufenta,sufentanyl", + "url": "https://psychonautwiki.org/wiki/Sufentanil", + "experiencesUrl": null, + "summary": "An synthetic analgesic drug that is roughly between 5-10x the potency of it's parent drug, (Fentanyl); It's use is very contained to surgery and post-operative pain.", + "reagents": null, + "classes": { + "chemical": [ + "Anilidopiperidine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "potentially fatal at heavy dosages", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines", + "unintentionally spilling a very small amount of sufentanil on one's skin could result in a fatal overdose." + ], + "addictionPotential": "extremely addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": null, + "zero": null + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Intravenous", + "dosage": [ + { + "name": "Threshold", + "value": "0.1 μg" + }, + { + "name": "Light", + "value": "1 - 5 μg" + }, + { + "name": "Common", + "value": "5 - 10 μg" + }, + { + "name": "Strong", + "value": "10 - 25 μg" + }, + { + "name": "Heavy", + "value": "25 μg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1 - 2 minutes" + }, + { + "name": "Peak", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "1 - 12 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "1-5ug" + }, + { + "name": "Common", + "value": "5-10ug" + }, + { + "name": "Strong", + "value": "10-25ug." + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "5-10 minutes" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 558, + "name": "Sulbutiamine", + "aliases": [ + "arcalion", + "bisibuthiamine", + "enerion", + "sulbut", + "youvitan" + ], + "aliasesStr": "arcalion,bisibuthiamine,enerion,sulbut,youvitan", + "url": "https://drugs.tripsit.me/sulbutiamine", + "experiencesUrl": null, + "summary": "A thiamine derivative nootropic and stimulant drug. Caution should be used as sulbutiamine reduces dopamine output over time with consistant usage.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "200-400mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 559, + "name": "Tabernanthe iboga (botany)", + "aliases": [ + "iboga" + ], + "aliasesStr": "iboga", + "url": "https://psychonautwiki.org/wiki/Tabernanthe_iboga_(botany)", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 560, + "name": "Tapentadol", + "aliases": [ + "nucynta", + "palexia", + "yantil", + "yantil sr" + ], + "aliasesStr": "nucynta,palexia,yantil,yantil sr", + "url": "https://psychonautwiki.org/wiki/Tapentadol", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_Tapentadol.shtml", + "summary": "An opioid analgesic drug with potency somewhere between tramadol and morphine, and with a similar action to Tramadol. Also an adrenergic reuptake inhibitor. High addiction potential. Potential for respiratory depression in overdose. Should not be combined with depressants or stimulants.", + "reagents": null, + "classes": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "12.5 mg" + }, + { + "name": "Light", + "value": "25 - 50 mg" + }, + { + "name": "Common", + "value": "50 - 75 mg" + }, + { + "name": "Strong", + "value": "75 - 150 mg" + }, + { + "name": "Heavy", + "value": "150 mg +" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15 - 45 minutes" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "After effects", + "value": "1 - 6 hours" + } + ] + }, + { + "name": "Oral_IR", + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + }, + { + "name": "Oral_ER", + "duration": [ + { + "name": "Onset", + "value": "60-120 minutes" + }, + { + "name": "Duration", + "value": "5-8 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 561, + "name": "Temazepam", + "aliases": [ + "normison", + "restoril" + ], + "aliasesStr": "normison,restoril", + "url": "https://psychonautwiki.org/wiki/Temazepam", + "experiencesUrl": null, + "summary": "Temazepam's brand name is Restoril. It is a hypnotic benzodiazepine with effects similar to clonazepam, frequently prescribed as a sleep aid. Some users report mild euphoria alongside the hypnotic effects.", + "reagents": null, + "classes": { + "chemical": [ + "Benzodiazepines" + ], + "psychoactive": [ + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of days of continuous use", + "half": null, + "zero": "7-14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "5 - 10 mg" + }, + { + "name": "Common", + "value": "10 - 25 mg" + }, + { + "name": "Strong", + "value": "25 - 40 mg" + }, + { + "name": "Heavy", + "value": "40 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "20 - 90 minutes" + }, + { + "name": "After effects", + "value": "6 - 12 hour" + } + ], + "bioavailability": "96%" + } + ], + "interactions": null + }, + { + "id": 562, + "name": "TETRAHYDROFURAN-FENTANYL", + "aliases": [ + "thf-f", + "thff" + ], + "aliasesStr": "thf-f,thff", + "url": "https://drugs.tripsit.me/tetrahydrofuran-fentanyl", + "experiencesUrl": null, + "summary": "An analogue of fentanyl that is unknown in literature. Is most likely less potent than most other analogues. Yet very few reports are around. Be careful.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 563, + "name": "Tetrazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/tetrazepam", + "experiencesUrl": null, + "summary": "A benzodiazepine that has most of the properties of more common benzodiazepines. Yet was taken off the market in 2013. Has been noted to be more euphoric than most others.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-200mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-35 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 564, + "name": "TH-PVP", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/th-pvp", + "experiencesUrl": null, + "summary": "A pyrovalerone stimulant related to a-PVP and naphyrone. Very little information about effects or safety profile, virtually no evidence of human use.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "20-30mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Strong", + "value": "50-70mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-30 minutes" + }, + { + "name": "Duration", + "value": "3-5 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "10-15mg" + }, + { + "name": "Common", + "value": "15-25mg" + }, + { + "name": "Strong", + "value": "25-35mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-15 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + } + ] + }, + { + "name": "Vapourized", + "dosage": [ + { + "name": "Light", + "value": "10-15mg" + }, + { + "name": "Common", + "value": "15-25mg" + }, + { + "name": "Strong", + "value": "25-35mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-2 minutes" + }, + { + "name": "Duration", + "value": "1 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 565, + "name": "Theacrine", + "aliases": [ + "temorine", + "temurin" + ], + "aliasesStr": "temorine,temurin", + "url": "https://psychonautwiki.org/wiki/Theacrine", + "experiencesUrl": null, + "summary": "Small alkaloid which can be seen as a structurally modified version of caffeine, with similar stimulating effects. It also shares anti-inflammatory and analgesic effects with caffeine.", + "reagents": null, + "classes": { + "chemical": [ + "Xanthines", + "Purine_alkaloid" + ], + "psychoactive": [ + "Stimulants", + "Nootropic" + ] + }, + "toxicity": null, + "addictionPotential": "produces dependence with chronic use and has a low abuse potential", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 150 mg" + }, + { + "name": "Strong", + "value": "150 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Common", + "value": "25 - 100 mg" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 566, + "name": "Thiopental", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/thiopental", + "experiencesUrl": null, + "summary": "Barbiturate that kicks in very quickly, that is used to Anesthesia, Medical induced comas among other things.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Intravenous", + "duration": [ + { + "name": "Onset", + "value": "0-2 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 567, + "name": "Thiopropamine", + "aliases": [ + "a-methyl-2-thipheneethanamine", + "normethiopropamine", + "tpa" + ], + "aliasesStr": "a-methyl-2-thipheneethanamine,normethiopropamine,tpa", + "url": "https://drugs.tripsit.me/thiopropamine", + "experiencesUrl": null, + "summary": "A substance that is closely related to Methiopopramine (MPA). Is roughly about 1/3rd the potency of amphetamine, differs from amphetmine from the phenyl ring is switched with a thiophene ring.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "20-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-125mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "1-4 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-15mg. minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 568, + "name": "THJ-018", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/THJ-018", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Naphthoylindazole" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "cannabinoids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 1 mg" + }, + { + "name": "Light", + "value": "1 - 2 mg" + }, + { + "name": "Common", + "value": "2 - 3 mg" + }, + { + "name": "Strong", + "value": "3 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "5 - 10 minutes" + }, + { + "name": "After effects", + "value": "60 - 90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 569, + "name": "THJ-2201", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/THJ-2201", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Naphthoylindazole" + ], + "psychoactive": [ + "Cannabinoid" + ] + }, + "toxicity": [ + "exact toxic dosage is unknown" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "cannabinoids" + ], + "roas": [ + { + "name": "Smoked", + "dosage": [ + { + "name": "Threshold", + "value": "< 0.5 mg" + }, + { + "name": "Light", + "value": "0.5 - 1 mg" + }, + { + "name": "Common", + "value": "1 - 2 mg" + }, + { + "name": "Strong", + "value": "2 - 5 mg" + }, + { + "name": "Heavy", + "value": "5 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "1 - 2 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Peak", + "value": "30 - 45 minutes" + }, + { + "name": "Offset", + "value": "0 - 0 minutes (Abrupt)" + }, + { + "name": "After effects", + "value": "60 - 90 minutes" + } + ] + } + ], + "interactions": null + }, + { + "id": 570, + "name": "Tianeptine", + "aliases": [ + "coaxil", + "stablon", + "tatinol" + ], + "aliasesStr": "coaxil,stablon,tatinol", + "url": "https://psychonautwiki.org/wiki/Tianeptine", + "experiencesUrl": null, + "summary": "A Tricyclic antidepressant, that has quite unique pharmacological properties than others in its class. Such as the possible indirect action on NMDA/AMPA and a full agonist at the μ-opioid receptor. While abuse of this substance is uncommon, it has been shown in a few countries.", + "reagents": null, + "classes": { + "chemical": [ + "Dibenzothiazepine", + "Tricyclic_antidepressant" + ], + "psychoactive": [ + "Nootropic", + "Opioids" + ] + }, + "toxicity": [ + "large therapeutic index and margin of safety" + ], + "addictionPotential": "mildly addictive", + "tolerance": { + "full": "with prolonged use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "trycyclic antidepressants", + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "3 mg" + }, + { + "name": "Light", + "value": "6 - 12 mg" + }, + { + "name": "Common", + "value": "12 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 100 mg" + }, + { + "name": "Heavy", + "value": "100 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "30 - 60 minutes" + }, + { + "name": "Come up", + "value": "15 - 30 minutes" + }, + { + "name": "Peak", + "value": "60 - 90 minutes" + }, + { + "name": "Offset", + "value": "30 - 60 minutes" + } + ], + "bioavailability": "99%" + } + ], + "interactions": null + }, + { + "id": 571, + "name": "Tiletamine", + "aliases": [ + "telazol" + ], + "aliasesStr": "telazol", + "url": "https://drugs.tripsit.me/tiletamine", + "experiencesUrl": null, + "summary": "A relatively rare dissociative anesthetic, pharmacologically classified as an NMDA receptor antagonist. It is related to other anesthetics in this family such as Ketamine and phencyclidine. Has been used to cut Ketamine, in which case it may cause additional nausea. In Veterinary practice it is mixed with Zolazolam, a potent anaesthetic at a 1:1 ratio.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50-100mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-45 minutes" + }, + { + "name": "Duration", + "value": "6-12 hours" + }, + { + "name": "After effects", + "value": "1-72 hours" + } + ] + }, + { + "name": "Intramuscular", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "1-4 hours" + }, + { + "name": "After effects", + "value": "1-72 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "2-10 minutes" + }, + { + "name": "Duration", + "value": "2-5 hours" + }, + { + "name": "After effects", + "value": "1-72 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 572, + "name": "Tilidine", + "aliases": [ + "tilidate", + "tilidin", + "valoron", + "valtran" + ], + "aliasesStr": "tilidate,tilidin,valoron,valtran", + "url": "https://drugs.tripsit.me/tilidine", + "experiencesUrl": null, + "summary": "Synthetic opioid, used mainly for treatment of moderate to severe pain. In some countries it's mixed with Naloxone to lower the abuse liability. Though in some only Tilidine. Roughly 0.2 - 1 on the potency scale to Morphine. (So 20mg's of Morphine to 100mg's Tilidine)", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Tilidine", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-200mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 573, + "name": "TMA-2", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/TMA-2", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_TMA2.shtml", + "summary": "Trimethoxyamphetamine-2, a psychedelic amphetamine and stimulant first synthesised by Alexander Shulgin. An uncommon compound of similar activity to other psychedelic amphetamines. Short history of human use.", + "reagents": null, + "classes": { + "chemical": [ + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 40 mg" + }, + { + "name": "Strong", + "value": "40 - 60 mg" + }, + { + "name": "Heavy", + "value": "60 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "8 - 12 hours" + }, + { + "name": "Onset", + "value": "20 - 120 minutes" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "4 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + }, + { + "name": "After effects", + "value": "4 - 24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 574, + "name": "TMA-6", + "aliases": [], + "aliasesStr": "", + "url": "https://psychonautwiki.org/wiki/TMA-6", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_TMA6.shtml", + "summary": "A rarely seen Psychedelic Amphetamine and Mescaline analogue. First synthesised by Alexander Shulgin, who descrived it as \"one of the most rewarding and pleasurable of the methoxylated amphetamines.\"", + "reagents": null, + "classes": { + "chemical": [ + "Amphetamine", + "Substituted_amphetamines" + ], + "psychoactive": [ + "Stimulants", + "Psychedelics" + ] + }, + "toxicity": [ + "toxic dose is unknown" + ], + "addictionPotential": "not habit-forming", + "tolerance": { + "full": "almost immediately after ingestion", + "half": "3 days", + "zero": "7 days" + }, + "crossTolerances": [ + "psychedelic" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 35 mg" + }, + { + "name": "Strong", + "value": "35 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "10 - 16 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Come up", + "value": "1.5 - 3 hours" + }, + { + "name": "Peak", + "value": "5 - 8 hours" + }, + { + "name": "Offset", + "value": "3 - 5 hours" + }, + { + "name": "After effects", + "value": "6 - 18 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 575, + "name": "Tolibut", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/tolibut", + "experiencesUrl": null, + "summary": "Analogue of GABA, and the 4-methyl analogue of Phenibut. Has similar effects, acts on GABA(B).", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 576, + "name": "Tramadol", + "aliases": [ + "tadol", + "tram", + "tramacur", + "tramal", + "tramundin" + ], + "aliasesStr": "tadol,tram,tramacur,tramal,tramundin", + "url": "https://psychonautwiki.org/wiki/Tramadol", + "experiencesUrl": null, + "summary": "A synthetic opioid analgesic, tramadol is used to treat moderate pain and can be considered a medium-strength opioid. Tramadol also has the unusual effect of being a serotonin releasing agent and a serotonin reuptake inhibitor, and as a consequence should not be taken in excess due to the risk of serotonin syndrome. Risk of seizures above 300mg doses.", + "reagents": null, + "classes": { + "chemical": [ + "Phenylpropylamine" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "25 mg" + }, + { + "name": "Light", + "value": "50 - 100 mg" + }, + { + "name": "Common", + "value": "100 - 250 mg" + }, + { + "name": "Strong", + "value": "250 - 300 mg" + }, + { + "name": "Heavy", + "value": "300 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "6 - 10 hours" + }, + { + "name": "Onset", + "value": "15 - 60 minutes" + }, + { + "name": "Come up", + "value": "30 - 60 minutes" + }, + { + "name": "Peak", + "value": "2 - 6 hours" + }, + { + "name": "Offset", + "value": "2 - 4 hours" + } + ], + "bioavailability": "70 - 90%" + } + ], + "interactions": [ + { + "status": "Unsafe", + "name": "2C-T-x" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics raise the risk of seizures.", + "name": "2C-x" + }, + { + "status": "Unsafe", + "name": "5-MeO-xxT" + }, + { + "status": "Dangerous", + "note": "Heavy CNS depressants, risk of seizures. Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place affected patients in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely.", + "name": "Alcohol" + }, + { + "status": "Dangerous", + "note": "Tramadol and stimulants both increase the risk of seizures.", + "name": "Amphetamines" + }, + { + "status": "Dangerous", + "note": "Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present. Vomit aspiration a risk when passed out, lay down in recovery position if ingested.", + "name": "Benzodiazepines" + }, + { + "status": "Low Risk & No Synergy", + "name": "Caffeine" + }, + { + "status": "Low Risk & Synergy", + "name": "Cannabis" + }, + { + "status": "Dangerous", + "note": "Tramadol and stimulants both increase the risk of seizures.", + "name": "Cocaine" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.", + "name": "DMT" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.", + "name": "DOx" + }, + { + "status": "Dangerous", + "name": "DXM" + }, + { + "status": "Dangerous", + "note": "The sedative effects of this combination can lead to dangerous respiratory depression.", + "name": "GHB/GBL" + }, + { + "status": "Dangerous", + "name": "Ketamine" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.", + "name": "LSD" + }, + { + "status": "Dangerous", + "name": "MAOIs" + }, + { + "status": "Dangerous", + "note": "Tramadol and stimulants both increase the risk of seizures.", + "name": "MDMA" + }, + { + "status": "Dangerous", + "name": "MXE" + }, + { + "status": "Unsafe", + "note": "This combination can cause seizures due to the lowering of the threshold by tramadol and the potential of mescaline to cause seziures.", + "name": "Mescaline" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and psychedelics also cause occasional seizures.", + "name": "Mushrooms" + }, + { + "status": "Unsafe", + "note": "Tramadol is well known to lower seizure threshold and NBOMes have also shown a tendency to cause severe seizures", + "name": "NBOMes" + }, + { + "status": "Caution", + "note": "Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.", + "name": "Nitrous" + }, + { + "status": "Dangerous", + "note": "Concomitant use of tramadol increases the seizure risk in patients taking other opioids. These agents are often individually epileptogenic and may have additive effects on seizure threshold during coadministration. Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present", + "name": "Opioids" + }, + { + "status": "Dangerous", + "name": "PCP" + }, + { + "status": "Dangerous", + "name": "SSRIs" + }, + { + "status": "Dangerous", + "name": "aMT" + } + ] + }, + { + "id": 577, + "name": "Trazodone", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/trazodone", + "experiencesUrl": null, + "summary": "A novel antidepressant of the SARI class, a serotonin antagonist and reuptake inhibitor. Often used to treat depression and anxiety. It has anxiolytic and hypnotic effects.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Light:", + "dosage": [ + { + "name": "Light", + "value": "25-50mg" + }, + { + "name": "Common", + "value": "50-100mg" + }, + { + "name": "Strong", + "value": "100-150" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-40 minutes" + }, + { + "name": "Duration", + "value": "6-10 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 578, + "name": "Triazolam", + "aliases": [ + "halcion" + ], + "aliasesStr": "halcion", + "url": "https://drugs.tripsit.me/triazolam", + "experiencesUrl": null, + "summary": "An uncommon and very short acting benzodiazepine. Sedating and hypnotic, and may induce amnesia and lowered inhibitions at high doses.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "0.125-0.25mg" + }, + { + "name": "Common", + "value": "0.25-0.5mg" + }, + { + "name": "Strong", + "value": "0.5-1.5mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-20 minutes" + }, + { + "name": "Duration", + "value": "4-7 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Duration", + "value": "3-5 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 579, + "name": "Troparil", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/troparil", + "experiencesUrl": null, + "summary": "A stimulant and dopamine reuptake inhibitor developed in the 1970s, it is frequently used in scientific research but has seen little usage outside of the lab. Similar effects to cocaine, though much longer and without any local anaesthetic action. Probably hard on the nose.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Common", + "value": "20-30mg" + }, + { + "name": "Strong", + "value": "30-60mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10 minutes" + }, + { + "name": "Duration", + "value": "45-70 minutes" + }, + { + "name": "After effects", + "value": "1-2 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 580, + "name": "Truffles", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/truffles", + "experiencesUrl": null, + "summary": "Truffles (magic truffles, sclerotium) are the thickened root sections of magic mushrooms. Like magic mushrooms, Truffles contain the psycho-active chemicals psilocybin and psilocin. See mushrooms for more information.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Wet", + "dosage": [ + { + "name": "Light", + "value": "5g" + }, + { + "name": "Common", + "value": "10g" + }, + { + "name": "Heavy", + "value": "15g+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + } + ] + }, + { + "name": "Dry", + "dosage": [ + { + "name": "Light", + "value": "0.5-1.5g" + }, + { + "name": "Common", + "value": "1.5-4g" + }, + { + "name": "Heavy", + "value": "4g+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-60 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 581, + "name": "Tuinal", + "aliases": [ + "beans", + "chirstmas-trees", + "jeebs", + "nawls", + "rainbows", + "tuinol" + ], + "aliasesStr": "beans,chirstmas-trees,jeebs,nawls,rainbows,tuinol", + "url": "https://drugs.tripsit.me/tuinal", + "experiencesUrl": null, + "summary": "Brand name of a combination drug of two barbiturate salts (Secobarbital/Amobarbital) in equal amounts. It was introduced in the late 1940's.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-75mg" + }, + { + "name": "Common", + "value": "75-150mg." + }, + { + "name": "Strong", + "value": "150-300mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-45 minutes" + }, + { + "name": "Duration", + "value": "5-12 hours" + }, + { + "name": "After effects", + "value": "1-8 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 582, + "name": "Tyrosine", + "aliases": [ + "l-tyrosine or 4-hydroxyphenylalanine" + ], + "aliasesStr": "l-tyrosine or 4-hydroxyphenylalanine", + "url": "https://psychonautwiki.org/wiki/Tyrosine", + "experiencesUrl": null, + "summary": null, + "reagents": null, + "classes": { + "chemical": [ + "Amino_acid", + "Substituted_phenethylamines" + ], + "psychoactive": [ + "Stimulants" + ] + }, + "toxicity": [ + "extremely low toxicity" + ], + "addictionPotential": "mildly habit forming", + "tolerance": { + "full": "after repeated and frequent usage", + "half": "7 days", + "zero": "14 days" + }, + "crossTolerances": [ + "dopamine" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "300 mg" + }, + { + "name": "Light", + "value": "500 - 1000 mg" + }, + { + "name": "Common", + "value": "1000 - 2000 mg" + }, + { + "name": "Strong", + "value": "2000 - 3000 mg" + }, + { + "name": "Heavy", + "value": "3000 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 4 hours" + }, + { + "name": "Onset", + "value": "30 - 90 minutes" + }, + { + "name": "Peak", + "value": "1 - 3 hours" + }, + { + "name": "After effects", + "value": "6 - 12 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 583, + "name": "U-47700", + "aliases": [ + "u47700" + ], + "aliasesStr": "u47700", + "url": "https://psychonautwiki.org/wiki/U-47700", + "experiencesUrl": "https://www.erowid.org/experiences/subs/exp_U47700.shtml", + "summary": "A µ-opioid receptor agonist that is related to AH-7921. Having a very short duration.", + "reagents": null, + "classes": { + "chemical": [ + "Benzamide" + ], + "psychoactive": [ + "Opioids" + ] + }, + "toxicity": [ + "high toxicity relative to its dose due to its extreme potency", + "potentially lethal when mixed with depressants like alcohol or benzodiazepines" + ], + "addictionPotential": "moderately addictive with a high potential for abuse", + "tolerance": { + "full": "develops with prolonged and repeated use", + "half": "3 - 7 days", + "zero": "1 - 2 weeks" + }, + "crossTolerances": [ + "opioids" + ], + "roas": [ + { + "name": "Insufflated", + "dosage": [ + { + "name": "Threshold", + "value": "1 mg" + }, + { + "name": "Light", + "value": "4 - 6 mg" + }, + { + "name": "Common", + "value": "6 - 8 mg" + }, + { + "name": "Strong", + "value": "8 - 10 mg" + }, + { + "name": "Heavy", + "value": "10 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "2 - 3 hours" + }, + { + "name": "Onset", + "value": "5 - 10 minutes" + }, + { + "name": "Come up", + "value": "15 - 20 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ] + }, + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "5-7.5mg" + }, + { + "name": "Common", + "value": "7.5-15mg" + }, + { + "name": "Strong", + "value": "15-25mg" + }, + { + "name": "Heavy", + "value": "25+mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "15 minutes" + }, + { + "name": "Duration", + "value": "5-7 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Insufflated/Plugged", + "duration": [ + { + "name": "Onset", + "value": "15 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Intravenous", + "duration": [ + { + "name": "Onset", + "value": "0-1 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 584, + "name": "U-49900", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/u-49900", + "experiencesUrl": null, + "summary": "A substance that is an analogue of U-47700, yet doesn't share much with it. If you are interested in trying it, I recommend reading this. https://www.reddit.com/r/researchchemicals/comments/5gbo3e/u49900_experiment_and_warning/", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 585, + "name": "U-51754", + "aliases": [ + "methene-u-47700", + "methene-u47700" + ], + "aliasesStr": "methene-u-47700,methene-u47700", + "url": "https://drugs.tripsit.me/u-51754", + "experiencesUrl": null, + "summary": "A very potent opioid, that seems to have a fair bit of κ-opioid action. So Dyshopria, Auditory hallucinations can be an effect. Is an analogue of U-47700.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Rectal", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-5mg" + }, + { + "name": "Strong", + "value": "5-10mg" + } + ], + "duration": [ + { + "name": "After effects", + "value": "3-6 hours" + } + ] + }, + { + "name": "Oral", + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "3-6 hours" + } + ] + }, + { + "name": "Insufflated", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "3-6 hours" + } + ] + }, + { + "name": "Plugged", + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "1-2 hours" + }, + { + "name": "After effects", + "value": "3-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 586, + "name": "Valerylfentanyl", + "aliases": [ + "vf" + ], + "aliasesStr": "vf", + "url": "https://drugs.tripsit.me/valerylfentanyl", + "experiencesUrl": null, + "summary": "Opioid that is a higher homologue of Butyrfentanyl with greatly reduced potency.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50+mg" + } + ] + } + ], + "interactions": null + }, + { + "id": 587, + "name": "Sildenafil", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/viagra", + "experiencesUrl": null, + "summary": "A medication originally developed to lower blood pressure, and now widely used to treat erectile dysfunction in men. Do not mix with anything that lowers blood pressure. Contact EMS if erection lasts longer than 4 hours.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-30mg" + }, + { + "name": "Common", + "value": "30-50mg" + }, + { + "name": "Strong", + "value": "50-100mg." + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-60 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 588, + "name": "Viloxazine", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/viloxazine", + "experiencesUrl": null, + "summary": "NRI that was used as an antidepressant in some European countries, and had a pronouced stimulant effect similar to amphetamines without any signs of dependence. Withdrawn in the early 2000s.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "50-75mg" + }, + { + "name": "Common", + "value": "75-150mg" + }, + { + "name": "Strong", + "value": "150mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-30 minutes" + }, + { + "name": "Duration", + "value": "3-6 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 589, + "name": "W-15", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/w-15", + "experiencesUrl": null, + "summary": "A potent opioid that is 5.4x more potent than Morphine. Has a distinct structure unrelated to nearly all other opioid compounds.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-15mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "15-40 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "2-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 590, + "name": "YERBA-MATE", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/yerba-mate", + "experiencesUrl": null, + "summary": "Is marketed for its ability to suppress appetite and burn fat. Yet only with high doses. It has a quite high ratio of caffeine. It has anti-inflammatory properties.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Common:", + "dosage": [ + { + "name": "Common", + "value": "1000-1500mg" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 591, + "name": "YOPO", + "aliases": [ + "\"anadenanthera", + "anadenanthera" + ], + "aliasesStr": "\"anadenanthera,anadenanthera", + "url": "https://drugs.tripsit.me/yopo", + "experiencesUrl": null, + "summary": "Anadenanthera peregrina, also known as yopo, is a perennial tree native to the Caribbean and South America. It is an entheogen containing 5-MeO-DMT and DMT, and is used in healing ceremonies and rituals. It is also a source of dietary calcium.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [], + "interactions": null + }, + { + "id": 592, + "name": "Zolazepam", + "aliases": [], + "aliasesStr": "", + "url": "https://drugs.tripsit.me/zolazepam", + "experiencesUrl": null, + "summary": "A substance that is structurally related to benzodiazepines. Is only used in Veterinary medicine. It is usually used in tandem with either the potent NMDA antagonist Tiletamine (at a 1:1 ratio) or with the α2 adrenergic receptor agonist Xylazine. Is roughly around four times the potency of Diazepam. Yet is water soluable.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "2.5-5mg" + }, + { + "name": "Common", + "value": "5-10mg" + }, + { + "name": "Strong", + "value": "10-20mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "10-30 minutes" + }, + { + "name": "Duration", + "value": "4-6 hours" + }, + { + "name": "After effects", + "value": "1-6 hours" + } + ] + }, + { + "name": "Insufflated", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-6mg" + }, + { + "name": "Strong", + "value": "6-12mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "5-10 minutes" + }, + { + "name": "Duration", + "value": "2-3 hours" + }, + { + "name": "After effects", + "value": "1-4 hours" + } + ] + }, + { + "name": "Intramuscular", + "dosage": [ + { + "name": "Light", + "value": "1-3mg" + }, + { + "name": "Common", + "value": "3-5mg" + }, + { + "name": "Strong", + "value": "5-10mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "1-5 minutes" + }, + { + "name": "Duration", + "value": "2-4 hours" + }, + { + "name": "After effects", + "value": "1-3 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 593, + "name": "Zolpidem", + "aliases": [ + "ambien", + "edluar", + "intermezzo", + "stilnox", + "zolpimist" + ], + "aliasesStr": "ambien,edluar,intermezzo,stilnox,zolpimist", + "url": "https://psychonautwiki.org/wiki/Zolpidem", + "experiencesUrl": null, + "summary": "Commonly prescribed for insomnia, Ambien (zolpidem) can cause realistic hallucinations similar to those of deliriants, and is very likely to cause amnesia at higher doses. Take care when using this drug, as it tends to lower inhibitions to a level which causes the user to do things they might not normally do when sober.", + "reagents": null, + "classes": { + "chemical": [ + "Imidazopyridine" + ], + "psychoactive": [ + "Hallucinogens", + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like alcohol or opioids" + ], + "addictionPotential": "moderately addictive", + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "5 mg" + }, + { + "name": "Light", + "value": "10 - 20 mg" + }, + { + "name": "Common", + "value": "20 - 30 mg" + }, + { + "name": "Strong", + "value": "30 - 50 mg" + }, + { + "name": "Heavy", + "value": "50 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "60 - 120 minutes" + }, + { + "name": "Onset", + "value": "5 - 30 minutes" + }, + { + "name": "Peak", + "value": "1 - 2 hours" + }, + { + "name": "Offset", + "value": "5 - 15 minutes" + }, + { + "name": "After effects", + "value": "2 - 4 hours" + } + ], + "bioavailability": "70%" + } + ], + "interactions": null + }, + { + "id": 594, + "name": "Zopiclone", + "aliases": [ + "imovane", + "zimovane" + ], + "aliasesStr": "imovane,zimovane", + "url": "https://psychonautwiki.org/wiki/Zopiclone", + "experiencesUrl": null, + "summary": "A nonbenzodiazepine sedative sleep aid (Z-drug), which can have hallucinogenic effects if taken while awake. Often causes users to have a metallic taste in the mouth for ~12h. Has been reported in some cases to cause certain users to black out, redose excessively and undertake dangerous activities such as driving.", + "reagents": null, + "classes": { + "chemical": [ + "Cyclopyrrolone" + ], + "psychoactive": [ + "Hallucinogens", + "Depressant" + ] + }, + "toxicity": [ + "low toxicity", + "potentially lethal when mixed with depressants like benzodiazepines, alcohol or opioids" + ], + "addictionPotential": "extremely physically and psychologically addictive", + "tolerance": { + "full": "within a couple of weeks of daily use", + "half": null, + "zero": "7 - 14 days" + }, + "crossTolerances": [ + "benzodiazepines" + ], + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Threshold", + "value": "2 mg" + }, + { + "name": "Light", + "value": "3.5 - 5 mg" + }, + { + "name": "Common", + "value": "5 - 7.5 mg" + }, + { + "name": "Strong", + "value": "7.5 - 15 mg" + }, + { + "name": "Heavy", + "value": "15 mg +" + } + ], + "duration": [ + { + "name": "Total", + "value": "3.5 - 9 hours" + }, + { + "name": "Onset", + "value": "10 - 30 minutes" + }, + { + "name": "Peak", + "value": "3 - 4 hours" + } + ], + "bioavailability": "52 - 59%" + } + ], + "interactions": null + }, + { + "id": 595, + "name": "α-PBP", + "aliases": [ + "a-pbp", + "alpha-pbp" + ], + "aliasesStr": "a-pbp,alpha-pbp", + "url": "https://drugs.tripsit.me/α-pbp", + "experiencesUrl": null, + "summary": "Stimulant that is the homologue between α-PPP and α-PVP.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "10-25mg" + }, + { + "name": "Common", + "value": "25-50mg" + }, + { + "name": "Strong", + "value": "50mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "20-35 minutes" + }, + { + "name": "Duration", + "value": "3-4 hours" + }, + { + "name": "After effects", + "value": "1-24 hours" + } + ] + } + ], + "interactions": null + }, + { + "id": 596, + "name": "βH-2C-B", + "aliases": [ + "beta-hydroxy-2c-b", + "bh-2c-b", + "bh-2cb", + "boh-2c-b", + "boh-2cb", + "bohb" + ], + "aliasesStr": "beta-hydroxy-2c-b,bh-2c-b,bh-2cb,boh-2c-b,boh-2cb,bohb", + "url": "https://drugs.tripsit.me/βh-2c-b", + "experiencesUrl": null, + "summary": "β-Hydroxy-2C-B is a novel analogue of 2C-B that is a bit less potent and has a longer duration. It's thought to be the active metabolite of βk-2C-B.", + "reagents": null, + "classes": null, + "toxicity": null, + "addictionPotential": null, + "tolerance": null, + "crossTolerances": null, + "roas": [ + { + "name": "Oral", + "dosage": [ + { + "name": "Light", + "value": "25-40mg" + }, + { + "name": "Common", + "value": "40-60mg" + }, + { + "name": "Strong", + "value": "60-75mg" + }, + { + "name": "Heavy", + "value": "75mg+" + } + ], + "duration": [ + { + "name": "Onset", + "value": "30-50 minutes" + }, + { + "name": "Duration", + "value": "7-10 hours" + }, + { + "name": "After effects", + "value": "1-12 hours" + } + ] + } + ], + "interactions": null + } +] \ No newline at end of file